Hydrocephalus

G6_HYDROCEPH

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 G91
  • Cause of death: ICD-10 G91

2 out of 7 registries used, show all original rules.

2694

4. Check minimum number of events

None

2694

5. Include endpoints

2967

6. Filter based on genotype QC (FinnGen only)

2967

Control definitions (FinnGen only)

Control exclude
G6_OTHNEU

Extra metadata

Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
G90-G99
Name in latin
Hydrocephalia

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 22296 10875 11155
Only index persons 16604 8404 8200
Unadjusted period prevalence (%)
Whole population 0.31 0.31 0.31
Only index persons 0.31 0.31 0.31
Median age at first event (years)
Whole population 62.99 64.83 61.03
Only index persons 62.42 64.39 60.41

-FinnGen-

Key figures

All Female Male
Number of individuals 2967 1504 1463
Unadjusted period prevalence (%) 0.58 0.51 0.64
Median age at first event (years) 68.12 67.21 69.06

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2719
Matched controls
27190
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G91.9
ICD-10 Finland
Hydrocephalus, unspecified
+∞
323.0
515
*
G91.0
ICD-10 Finland
Communicating hydrocephalus
7937.5
323.0
628
*
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
6340.4
323.0
1391
*
AAF20
NOMESCO Finland
Revision of shunt of ventricle of brain
+∞
323.0
479
*
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
17.7
323.0
743
564
AA1AD
NOMESCO Finland
CT of head and brain
8.5
323.0
1620
4004
G91.2
ICD-10 Finland
Normal-pressure hydrocephalus
16384.0
323.0
1601
*
AAF00
NOMESCO Finland
Ventriculostomy
360.8
323.0
450
15
G91.1
ICD-10 Finland
Obstructive hydrocephalus
+∞
323.0
484
*
AA7AA
NOMESCO Finland
Liquor cerebri shunt X-ray examinatin without contrast
3444.4
323.0
317
*
AA1AA
NOMESCO Finland
Head X-ray examination
73.9
316.6
360
56
AAF15
NOMESCO Finland
Ventriculoatrial shunt
2610.9
261.5
249
*
AAF25
NOMESCO Finland
Removal of shunt of ventricle of brain
2118.7
216.4
207
*
T85.0
ICD-10 Finland
Mechanical complication of ventricular intracranial (communicating) shunt
1981.1
203.6
195
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
7.7
197.9
502
781
AAA20
NOMESCO Finland
Insertion of intraventricular pressure monitoring device
990.1
191.0
185
*
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
7.0
188.0
506
854
I69.0
ICD-10 Finland
Sequelae of subarachnoid haemorrhage
31.2
178.1
240
84
R26.8
ICD-10 Finland
Other and unspecified abnormalities of gait and mobility
14.3
158.1
278
215
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
27.0
155.0
217
87
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
5.8
150.9
471
947
I60.9
ICD-10 Finland
Subarachnoid haemorrhage, unspecified
20.2
143.1
219
117
AAF99
NOMESCO Finland
Other shunt operation on ventricle of brain or intracerebral cyst
477.9
138.5
137
*
G91.8
ICD-10 Finland
Other hydrocephalus
+∞
132.4
126
*
TAA40
NOMESCO Finland
Cathetrisation of cerebrospinal fluid through skin
313.1
118.1
119
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.1
110.7
751
2986
P20
ICPC
Memory disturbance
3.2
109.8
680
2533
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
7.1
107.1
278
429
ZXD05
NOMESCO Finland
Urgent procedure
2.5
100.8
1087
5670
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
5.6
98.1
308
607
3313A
ICD-9 Finland
Other cerebral degenerations, Communicating hydrocephalus
+∞
96.4
92
*
R42
ICD-10 Finland
Dizziness and giddiness
2.7
96.1
851
3945
G91.3
ICD-10 Finland
Post-traumatic hydrocephalus, unspecified
+∞
92.2
88
*
G45.1
ICD-10 Finland
Carotid artery syndrome (hemispheric)
+∞
89.0
85
*
SPAT1229
SPAT
Assessment of need for aid
3.7
88.6
428
1292
AAF50
NOMESCO Finland
Third ventriculostomy
+∞
88.0
84
*
L28
ICPC
Limited function/disability (L)
2.8
86.3
694
3006
SPAT1216
SPAT
Assessment of functional ability
2.7
86.0
700
3054
R51.80
ICD-10 Finland
Headache
3.2
81.7
492
1753
PA2BC
NOMESCO Finland
Cerebral extensive angiography with X-ray
19.8
80.3
123
65
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
3.4
79.4
434
1436
N03AX14
ATC
levetiracetam; systemic
8.0
78.5
186
248
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
3.4
76.1
411
1346
2132
FHL
Ventricular operators sunt
748.0
74.6
73
*
TAB00
NOMESCO Finland
Lumbar puncture
6.1
73.8
212
371
A28
ICPC
Limited function/disability NOS
2.5
73.0
683
3184
XA800
NOMESCO Finland
Neuropsychological investigation
6.3
70.9
199
338
R53
ICD-10 Finland
Malaise and fatigue
2.4
69.7
726
3569
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.5
69.4
655
3055
N03AG01
ATC
valproic acid; systemic, rectal
4.5
69.1
263
632
SPAT1053
SPAT
Memory test
2.4
67.4
691
3360
I60.2
ICD-10 Finland
Subarachnoid haemorrhage from anterior communicating artery
26.0
66.3
93
37
Z98.2
ICD-10 Finland
Presence of cerebrospinal fluid drainage device
+∞
65.9
63
*
K90
ICPC
Stroke/cerebrovascular accident
5.9
64.9
192
348
G45.0
ICD-10 Finland
Vertebro-basilar artery syndrome
329.6
64.7
65
*
AAC00
NOMESCO Finland
Ligature of intracranial aneurysm
13.6
64.6
114
87
PA2CC
NOMESCO Finland
Cerebral very extensive angiography with X-ray
22.6
64.3
94
43
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.1
63.4
1012
6004
I69.1
ICD-10 Finland
Sequelae of intracerebral haemorrhage
11.4
61.5
118
108
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
6.8
61.2
161
250
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
8.5
60.8
137
168
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.4
60.2
608
2908
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
3.3
59.6
332
1101
F03
ICD-10 Finland
Unspecified dementia
3.8
57.4
261
736
G40.9
ICD-10 Finland
Epilepsy, unspecified
5.4
56.9
179
349
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.7
56.7
264
759
ZXE10
NOMESCO Finland
More than one and less than three hours
2.0
56.7
1097
6944
PA2BD
NOMESCO Finland
Extensive CT angiography of brain
9.0
56.4
123
143
I62.0
ICD-10 Finland
Nontraumatic subdural haemorrhage
16.1
56.0
92
59
PA2LT
NOMESCO Finland
Endovascular closure of extensive brain aneurysm
39.9
55.6
70
18
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
8.7
55.5
123
147
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.3
54.0
565
2730
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.8
53.4
379
1475
I60.7
ICD-10 Finland
Subarachnoid haemorrhage from intracranial artery, unspecified
32.6
53.1
70
22
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
9.4
53.0
112
123
3314A
ICD-9 Finland
Other cerebral degenerations, Obstructive hydrocephalus
+∞
52.2
50
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.3
52.0
563
2763
N28
ICPC
Limited function/disability (N)
8.5
51.8
116
141
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
13.2
51.6
92
72
I60.1
ICD-10 Finland
Subarachnoid haemorrhage from middle cerebral artery
18.7
51.6
80
44
N18
ICPC
Paralysis/weakness
7.1
51.2
130
192
U04
ICPC
Incontinence urine
3.7
50.8
235
671
N04BA02
ATC
levodopa and decarboxylase inhibitor; oral
4.2
50.7
204
514
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
7.2
49.8
124
178
S06.0
ICD-10 Finland
Concussion
2.8
49.7
362
1427
N99
ICPC
Neurological disease other
9.7
49.6
103
110
I60.0
ICD-10 Finland
Subarachnoid haemorrhage from carotid siphon and bifurcation
43.7
48.6
60
14
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
3.0
48.2
300
1070
2133
FHL
Suntin revisio
+∞
47.0
45
*
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
2.7
47.0
357
1444
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.9
46.8
880
5411
R56.8
ICD-10 Finland
Other and unspecified convulsions
4.0
46.7
199
528
N05AX08
ATC
risperidone; systemic
2.8
46.6
326
1251
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
2.5
45.7
393
1701
SPAT1245
SPAT
Provision of support and information to patient’s family members
3.4
45.3
239
756
AAD10
NOMESCO Finland
Evacuation of chronic subdural haematoma
7.6
44.5
107
146
I61.9
ICD-10 Finland
Intracerebral haemorrhage, unspecified
7.2
44.5
111
160
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.3
43.4
473
2307
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
3.5
42.9
218
669
N03AF02
ATC
oxcarbazepine; oral
5.3
42.9
135
263
G94.2
ICD-10 Finland
Hydrocephalus in other diseases classified elsewhere
+∞
42.8
41
*
N29
ICPC
Neurological sympt/complt other
6.8
42.5
110
167
307
Kela drug reimbursment
Tacrine, donepezil, rivastigmine, galantamine and other major and expensive drugs used to treat Alzheimer's disease
3.1
42.3
246
835
N06AB04
ATC
citalopram; systemic
2.0
42.0
604
3324
N05AH04
ATC
quetiapine; oral
2.3
41.5
443
2134
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
2.8
40.4
280
1066
SPAT1234
SPAT
Support of social functional capacity
3.1
39.8
234
800
AAL00
NOMESCO Finland
Endovascular occlusion of intracranial aneurysm
36.3
39.1
50
14
G93.0
ICD-10 Finland
Cerebral cysts
+∞
38.6
37
*
N02BE01
ATC
paracetamol; systemic, rectal
1.9
38.5
2262
19562
Z2445
NOMESCO Finland
Psychologist
4.5
38.0
141
328
I67.1
ICD-10 Finland
Cerebral aneurysm, nonruptured
6.8
37.6
97
147
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
4.2
36.8
144
353
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.1
36.7
468
2434
Q03.9
ICD-10 Finland
Congenital hydrocephalus, unspecified
+∞
36.5
35
*
N06DX01
ATC
memantine; oral
2.5
35.7
299
1269
N06DA02
ATC
donepezil; oral
2.6
35.4
272
1097
G04BD07
ATC
tolterodine; oral
2.9
35.4
231
843
N03AB02
ATC
phenytoin; systemic
7.1
35.3
88
127
N39.4
ICD-10 Finland
Other specified urinary incontinence
2.5
35.3
304
1307
SPAT1254
SPAT
Administration of medicine
2.0
35.0
503
2743
R41.0
ICD-10 Finland
Disorientation, unspecified
4.0
35.0
147
385
ZSA00
NOMESCO Finland
Procedure related to previous procedure classified in chapter A
21.6
34.8
51
24
N03AF01
ATC
carbamazepine; oral, rectal
3.2
34.7
197
655
G97.2
ICD-10 Finland
Intracranial hypotension following ventricular shunting
+∞
34.4
33
*
G04BD12
ATC
mirabegron; oral
2.2
34.3
370
1781
I60.6
ICD-10 Finland
Subarachnoid haemorrhage from other intracranial arteries
42.6
34.1
42
10
A06AD11
ATC
lactulose; oral
2.0
33.5
517
2892
R1250
NOMESCO Finland
Evaluation of functional capability
5.2
33.3
106
210
N30.0
ICD-10 Finland
Acute cystitis
2.1
32.8
427
2230
H47.2
ICD-10 Finland
Optic atrophy
17.9
32.7
51
29
R90.8
ICD-10 Finland
Other abnormal findings on diagnostic imaging of central nervous system
13.5
32.7
57
43
SPAT1231
SPAT
Assessment of adjustments needed in living environment
4.6
32.7
117
263
PA2KT
NOMESCO Finland
Endovascular closure of brain aneurysm
31.2
32.6
43
14
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
3.6
32.4
155
453
P70
ICPC
Dementia
4.4
31.7
118
276
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.8
31.5
217
819
ZXC86
NOMESCO Finland
Use of endoscopic device
17.0
31.5
50
30
N06AB10
ATC
escitalopram; oral
2.0
31.4
457
2493
7423A
ICD-9 Finland
Other congenital anomalies of nervous system, Congenital hydrocephalus
+∞
31.3
30
*
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
3.9
31.2
133
353
K91
ICPC
Cerebrovascular disease
6.3
30.9
84
137
G30.1
ICD-10 Finland
Alzheimer disease with late onset
2.4
30.7
270
1171
74200
ICD-8 Finland
Congenital hydrocephalus, Communicans
+∞
30.3
29
*
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
29.9
717
4642
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.0
29.7
461
2571
T90.5
ICD-10 Finland
Sequelae of intracranial injury
8.8
29.7
64
74
SPAT1301
SPAT
No procedures
1.7
29.4
915
6379
G04BD08
ATC
solifenacin; oral
2.4
29.4
262
1143
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
8.9
29.4
63
72
N06DA03
ATC
rivastigmine; oral, transdermal
2.9
29.4
188
676
A04
ICPC
Weakness/tiredness general
2.0
29.2
403
2150
PA2MT
NOMESCO Finland
Endovascular closure of very extensive brain aneurysm
57.3
29.1
34
6
I60.3
ICD-10 Finland
Subarachnoid haemorrhage from posterior communicating artery
40.5
29.0
36
9
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
8.3
28.5
64
79
PA3AC
NOMESCO Finland
Carotis angiography with X-ray
19.0
28.3
43
23
G30.9
ICD-10 Finland
Alzheimer disease, unspecified
3.0
28.2
167
572
Q03.0
ICD-10 Finland
Malformations of aqueduct of Sylvius
+∞
28.2
27
*
34793
ICD-8 Finland
Other disease of brain, Hydrocephalus acquisitus NUD
+∞
28.2
27
*
183
Kela drug reimbursment
Lamotrigin and topiramate
10.4
27.9
55
54
F06.7
ICD-10 Finland
Mild cognitive disorder
3.6
27.6
130
376
AA1BM
NOMESCO Finland
MRI examination of brain with 3 Tesla magnet
8.2
27.1
61
76
Y83.1
ICD-10 Finland
Surgical operation with implant of artificial internal device as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
5.7
27.0
79
142
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.2
26.7
280
1324
G20
ICD-10 Finland
Parkinson disease
3.2
26.5
142
454
H53.4
ICD-10 Finland
Visual field defects
5.0
26.2
86
177
N06AX11
ATC
mirtazapine; oral
1.6
26.1
774
5285
XCK00
NOMESCO Finland
Perimetry
2.4
26.0
235
1031
G04BD04
ATC
oxybutynin; oral, transdermal
2.5
26.0
210
870
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
5.6
26.0
77
141
I61.0
ICD-10 Finland
Intracerebral haemorrhage in hemisphere, subcortical
4.8
26.0
89
192
ZXA00
NOMESCO Finland
Right side
1.6
25.7
770
5269
SPAT1252
SPAT
Overall medication plan or its review
2.3
25.6
251
1148
D33.30
ICD-10 Finland
Acoustic neuroma
10.8
25.5
49
46
AA1BD
NOMESCO Finland
Extensive CT of head and brain
3.8
25.3
109
293
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
9.4
25.2
52
56
G41.9
ICD-10 Finland
Status epilepticus, unspecified
12.0
25.2
46
39
74209
ICD-8 Finland
Congenital hydrocephalus, Unspecified
+∞
25.0
24
*
G91
ICD-10 Finland
Hydrocephalus
+∞
25.0
24
*
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.3
25.0
239
1079
I61.5
ICD-10 Finland
Intracerebral haemorrhage, intraventricular
27.8
24.5
33
12
WYA20
NOMESCO Finland
Home visit
4.5
24.0
87
199
R55
ICD-10 Finland
Syncope and collapse
2.0
24.0
337
1799
G93.2
ICD-10 Finland
Benign intracranial hypertension
+∞
24.0
23
*
2130
FHL
Ventricular atrial shunt
+∞
24.0
23
*
F00.10*G30.1
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
3.0
23.7
143
496
G81.1
ICD-10 Finland
Spastic hemiplegia
241.9
23.7
24
*
AA5PD
NOMESCO Finland
CT examination of brain pefusion
8.9
23.5
50
57
S06.3
ICD-10 Finland
Focal brain injury
5.9
23.4
66
114
PA2AD
NOMESCO Finland
CT angiography of brain
13.0
23.4
41
32
N03AX18
ATC
lacosamide; systemic
13.0
23.4
41
32
W19
ICD-10 Finland
Unspecified fall
2.1
23.2
283
1429
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
4.0
23.0
94
241
N05BA09
ATC
clobazam; oral
11.8
23.0
42
36
AAF10
NOMESCO Finland
Lumboperitoneal shunt
+∞
22.9
22
*
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.3
22.8
222
1009
M48.0
ICD-10 Finland
Spinal stenosis
1.9
22.8
371
2092
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
2.9
22.8
146
526
N05BA04
ATC
oxazepam; oral
1.6
22.3
626
4184
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.6
22.3
723
5017
PA4AC
NOMESCO Finland
Vertebralis angiography with X-ray
27.5
22.2
30
11
N05BA01
ATC
diazepam; systemic, rectal
1.9
22.0
363
2057
H47.1
ICD-10 Finland
Papilloedema, unspecified
11.9
22.0
40
34
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
4.8
21.9
74
158
G99.2*M47.1
ICD-10 Finland
Spondylogenic compression of spinal cord
+∞
21.9
21
*
NA7BG
NOMESCO Finland
Spine and spinal cord MRI examination with high intensity magnet
10.6
21.8
42
40
G46.4*I67.9
ICD-10 Finland
Cerebellar stroke syndrome
221.6
21.6
22
*
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.8
21.6
386
2248
G25.9
ICD-10 Finland
Extrapyramidal and movement disorder, unspecified
5.9
21.6
61
106
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
3.9
21.6
89
231
ZXD35
NOMESCO Finland
Usual procedure
3.0
21.3
128
443
R4150
NOMESCO Finland
Neuropsychological rehabilitation
14.0
21.3
36
26
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
5.6
21.3
62
112
D43.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, infratentorial
34.0
21.1
27
8
N03AX09
ATC
lamotrigine; oral
3.3
21.1
109
340
AAD05
NOMESCO Finland
Evacuation of acute subdural haematoma
10.7
20.8
40
38
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
2.3
20.8
196
878
F00.20*G30.8
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type without additional symptoms
3.8
20.8
89
239
N05AH03
ATC
olanzapine; systemic
2.6
20.6
150
586
SPAT1101
SPAT
Orthostatic test
2.4
20.6
182
791
Z03
ICPC
Housing/neighbourhood problem
8.7
20.6
44
51
AAK80
NOMESCO Finland
Partial excision of skull cap
110.8
20.6
22
*
R26.2
ICD-10 Finland
Difficulty in walking, not elsewhere classified
5.5
20.2
60
111
J01CA08
ATC
pivmecillinam; oral
1.5
20.1
923
6921
SPAT1215
SPAT
Assessment of need for medical rehabilitation
2.7
20.1
146
569
XXA00
NOMESCO Finland
Clinical examination requiring general anaesthesia
9.4
20.1
41
44
I60.4
ICD-10 Finland
Subarachnoid haemorrhage from basilar artery
36.0
19.8
25
7
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.8
19.5
396
2397
AWB00
NOMESCO Finland
Reoperation for superficial infection in surgery of the nervous system
24.8
19.5
27
11
AA5BD
NOMESCO Finland
CT of cerebral ischaemia
4.2
19.5
75
183
PA2YT
NOMESCO Finland
Cerebral artery PTA with stent
19.5
19.5
29
15
R32
ICD-10 Finland
Unspecified urinary incontinence
3.1
19.4
110
366
AAA27
NOMESCO Finland
Insertion of intracerebral pressure monitoring device
46.3
19.2
23
5
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
8.3
19.2
42
51
N06AX16
ATC
venlafaxine; oral
1.9
19.1
281
1524
T85.7
ICD-10 Finland
Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
26.2
19.1
26
10
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
6.8
19.1
48
72
G44.2
ICD-10 Finland
Tension-type headache
1.9
19.0
289
1586
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
4.2
18.9
72
174
R11
ICD-10 Finland
Nausea and vomiting
2.1
18.9
228
1140
R26.0
ICD-10 Finland
Ataxic gait
15.9
18.8
30
19
G942, I602
ICD-10 Finland
NA
+∞
18.8
18
*
2139
FHL
Other measure in this category
+∞
18.8
18
*
Z00.0
ICD-10 Finland
General medical examination
1.7
18.8
455
2903
I60.5
ICD-10 Finland
Subarachnoid haemorrhage from vertebral artery
191.2
18.5
19
*
F05.9
ICD-10 Finland
Delirium, unspecified
3.7
18.4
82
228
WX320
NOMESCO Finland
Spinalanesthesy
0.6
18.4
246
4094
AAA10
NOMESCO Finland
Biopsy through craniotomy
30.2
18.3
24
8
Z75.5
ICD-10 Finland
Holiday relief care
5.3
18.3
56
108
Z02.4
ICD-10 Finland
Examination for driving licence
0.6
18.2
300
4739
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.9
18.2
272
1483
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.8
18.2
327
1901
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
3.9
17.9
75
198
4300A
ICD-9 Finland
Subarachnoid haemorrhage[HAEMORRHAGIA SUBARACHNOID. POST ANEURYSMA SACCULARE]
10.1
17.9
35
35
SPAT1042
SPAT
Guidance concerning balance maintenance
9.6
17.9
36
38
SPAT1167
SPAT
Insertion of urinary catheter
2.7
17.8
123
467
G00.9
ICD-10 Finland
Bacterial meningitis, unspecified
22.9
17.7
25
11
G97.0
ICD-10 Finland
Cerebrospinal fluid leak from spinal puncture
+∞
17.7
17
*
A29
ICPC
General symptom/complaint other
1.8
17.5
314
1824
WX730
NOMESCO Finland
Conventional respirator
4.2
17.4
66
160
G30.8
ICD-10 Finland
Other Alzheimer disease
3.1
17.3
97
322
SPAT1251
SPAT
Organisation of medication
2.5
16.9
134
549
-
ICD-10 Finland
NA
3.3
16.9
85
261
G40.2
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
6.6
16.9
43
66
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
5.6
16.6
48
87
2161
FHL
Neck ligation, big brain
9.5
16.4
33
35
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.7
16.1
113
434
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
4.8
16.0
53
112
J01EA01
ATC
trimethoprim; systemic
1.5
16.0
651
4703
C71.60
ICD-10 Finland
Malignant tumor of cerebellum without histology
47.8
16.0
19
*
N05AB03
ATC
perphenazine; systemic, rectal
2.9
15.9
99
353
R50.9
ICD-10 Finland
Fever, unspecified
1.7
15.8
343
2108
G40.10
ICD-10 Finland
Simple partial seizures
7.1
15.8
38
54
M03BX01
ATC
baclofen; systemic
4.5
15.7
55
124
2127
FHL
Ventriculostomy
+∞
15.6
15
*
PA2AC
NOMESCO Finland
Cerebral angiography with X-ray
13.8
15.5
26
19
D33.07
ICD-10 Finland
Colloid coast in cerebral ventricle
38.3
15.4
19
5
G04CA02
ATC
tamsulosin; oral
1.5
15.3
644
4682
H49.2
ICD-10 Finland
Sixth [abducent] nerve palsy
5.4
15.2
45
84
AAK00
NOMESCO Finland
Cranioplasty
28.7
15.2
20
7
H53.2
ICD-10 Finland
Diplopia
2.9
15.1
93
329
D33.00
ICD-10 Finland
Medial pilosytic astrocytoma of the cerebrum
23.5
15.1
21
9
G03.9
ICD-10 Finland
Meningitis, unspecified
20.1
15.1
22
11
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.6
15.1
483
3301
110
Kela drug reimbursment
Parkinson's disease and comparable movement disrorders
2.6
14.9
106
411
S72.0
ICD-10 Finland
Fracture of neck of femur
2.2
14.6
149
693
G95.0
ICD-10 Finland
Syringomyelia and syringobulbia
+∞
14.6
14
*
AXX01
SPAT
NA
4.3
14.6
53
124
2124
FHL
Intracranial pressure measurement, intraventricular
80.5
14.6
16
*
D32.02
ICD-10 Finland
Benign tumor of the meninges at the base of the brain
5.5
14.5
42
77
SPAT1262
SPAT
Handing over of treatment supplies
1.5
14.4
479
3297
N06AB06
ATC
sertraline; oral
1.9
14.4
216
1179
N02AA05
ATC
oxycodone; systemic
1.6
14.3
409
2714
SPAT1221
SPAT
Guidance concerning rehabilitation services and livelihood
3.9
14.3
58
151
N80
ICPC
Head injury other
3.6
14.2
64
182
G40.89
ICD-10 Finland
Other epilepsy
12.0
14.1
25
21
N06AB03
ATC
fluoxetine; oral
1.8
14.0
277
1654
GBB00
NOMESCO Finland
Tracheostomy
4.3
14.0
51
120
SPAT1295
SPAT
Other function in accordance with physical therapy nomenclature
2.1
14.0
153
738
R26
ICD-10 Finland
Abnormalities of gait and mobility
12.7
13.9
24
19
G40.19
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
7.1
13.8
33
47
X59
ICD-10 Finland
Exposure to unspecified factor
1.6
13.7
413
2775
G90.2
ICD-10 Finland
Horner syndrome
75.5
13.6
15
*
SPAT1305
SPAT
Counselling and guidance related to physical exercise
1.8
13.6
253
1486
N03AE01
ATC
clonazepam; systemic
2.1
13.6
147
705
Q05.2
ICD-10 Finland
Lumbar spina bifida with hydrocephalus
+∞
13.5
13
*
G93.1
ICD-10 Finland
Anoxic brain damage, not elsewhere classified
140.6
13.5
14
*
Z02.7
ICD-10 Finland
Issue of medical certificate
2.1
13.4
155
762
R4120
NOMESCO Finland
Occupational therapy
2.1
13.3
154
758
9530/0-C70.0
ICD-O-3
Meningioma, NOS, of cerebral meninges
5.6
13.3
38
69
S06.6
ICD-10 Finland
Traumatic subarachnoid haemorrhage
4.8
13.3
43
90
JDB10
NOMESCO Finland
Percutaneous gastrostomy
3.9
13.2
53
137
G04BD09
ATC
trospium; oral
2.6
13.1
94
367
R47.0
ICD-10 Finland
Dysphasia and aphasia
5.0
13.0
41
83
G41.2
ICD-10 Finland
Complex partial status epilepticus
16.8
13.0
20
12
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
0.6
12.9
299
4409
XX4AW
NOMESCO Finland
NA
13.0
12.9
22
17
AAB30
NOMESCO Finland
Evacuation of spontaneous intracranial haematoma
14.1
12.7
21
15
R1260
NOMESCO Finland
Evaluation of communicative skills
3.5
12.7
59
173
PA7CD
NOMESCO Finland
CT angiography of neck and brain, extensive
4.8
12.7
41
86
L99
ICPC
Musculoskeletal disease other
3.3
12.5
63
196
G95.8
ICD-10 Finland
Other specified diseases of spinal cord
130.5
12.4
13
*
I60.8
ICD-10 Finland
Other subarachnoid haemorrhage
13.2
12.4
21
16
R27.0
ICD-10 Finland
Ataxia, unspecified
7.6
12.4
28
37
N87
ICPC
Parkinsonism
3.6
12.3
55
156
Q07.0
ICD-10 Finland
Arnold-Chiari syndrome
37.7
12.2
15
*
L29
ICPC
Musculoskeletal sympt/complt other
1.9
12.1
188
1036
Z08
ICPC
Social welfare problem
4.5
12.1
42
95
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
1.9
12.0
191
1061
I62.9
ICD-10 Finland
Intracranial haemorrhage (nontraumatic), unspecified
21.4
12.0
17
8
D43.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, supratentorial
7.2
12.0
28
39
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.8
12.0
216
1254
XCW99
NOMESCO Finland
Other investigative procedure of eye
1.6
12.0
295
1880
SPAT1304
SPAT
Counselling and guidance related to ageing
1.7
11.8
230
1370
N31.9
ICD-10 Finland
Neuromuscular dysfunction of bladder, unspecified
5.6
11.8
33
59
J01MA02
ATC
ciprofloxacin; systemic
1.4
11.6
940
7632
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.4
11.6
752
5885
SAD01
NOMESCO Finland
Assessment of need for oral health care, standard
1.7
11.6
247
1511
S01.0
ICD-10 Finland
Open wound of scalp
1.8
11.6
200
1145
C71.90
ICD-10 Finland
Malignant tumor in unspecified localization in the brain without histology
10.1
11.5
22
22
7410D
ICD-9 Finland
Spina bifida, With hydrocephalus[SPINA BIFIDA APERTA CUM HYDROCEPHALO REG LUMBALIS]
+∞
11.5
11
*
G942, I615
ICD-10 Finland
NA
+∞
11.5
11
*
ABE50
NOMESCO Finland
Occipitocervical decompression
+∞
11.5
11
*
C71.69
ICD-10 Finland
Malignant tumor of the cerebellum other or unspecified histology
120.4
11.4
12
*
101
Kela drug reimbursment
Anterior pituitary hypofunction
6.7
11.4
28
42
ZXE20
NOMESCO Finland
More than three and less than five hours
1.6
11.4
349
2347
F00.10
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
3.0
11.3
65
221
XKC03
NOMESCO Finland
Water cystometry
2.5
11.3
90
374
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.4
11.3
720
5616
G45.8
ICD-10 Finland
Other transient cerebral ischaemic attacks and related syndromes
35.1
11.3
14
*
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
3.4
11.2
53
158
I61.1
ICD-10 Finland
Intracerebral haemorrhage in hemisphere, cortical
5.1
11.2
34
67
SPAT1100
SPAT
Long-term monitoring of blood pressure
1.8
11.1
207
1216
G40.21
ICD-10 Finland
Partial epileptic seizure with cloudiness and automatism
10.1
11.0
21
21
N30.9
ICD-10 Finland
Cystitis, unspecified
2.0
10.9
145
756
I67.9
ICD-10 Finland
Cerebrovascular disease, unspecified
5.7
10.9
30
53
I69.2
ICD-10 Finland
Sequelae of other nontraumatic intracranial haemorrhage
11.9
10.8
19
16
I10
ICD-10 Finland
Essential (primary) hypertension
1.3
10.8
1535
13500
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
2.0
10.8
132
669
SPAT1249
SPAT
Treatment-related counselling outside office
1.3
10.8
914
7455
G21.9
ICD-10 Finland
Secondary parkinsonism, unspecified
7.2
10.7
25
35
G40.1
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
9.6
10.7
21
22
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
5.8
10.7
29
50
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
4.4
10.7
37
84
F31.0
ICD-10 Finland
Bipolar affective disorder, current episode hypomanic
4.4
10.7
37
84
G40
ICD-10 Finland
Epilepsy
5.6
10.7
30
54
WX704
NOMESCO Finland
Intubation
1.9
10.7
161
880
G31.9
ICD-10 Finland
Degenerative disease of nervous system, unspecified
8.0
10.6
23
29
E23.00
ICD-10 Finland
Panhypopituitarism
8.5
10.5
22
26
I69.8
ICD-10 Finland
Sequelae of other and unspecified cerebrovascular diseases
6.5
10.5
26
40
WX882
NOMESCO Finland
High dependency care
2.4
10.4
88
378
P52.2
ICD-10 Finland
Intraventricular (nontraumatic) haemorrhage, grade 3, and grade 4 of fetus and newborn
+∞
10.4
10
*
G46.3*I67.9
ICD-10 Finland
Brain stem stroke syndrome (I60-I67+)
+∞
10.4
10
*
G942, I601
ICD-10 Finland
NA
+∞
10.4
10
*
74201
ICD-8 Finland
Congenital hydrocephalus, Non communicans
+∞
10.4
10
*
G94.1
ICD-10 Finland
Hydrocephalus in neoplastic disease
+∞
10.4
10
*
74210
ICD-8 Finland
NA
+∞
10.4
10
*
Q03.1
ICD-10 Finland
Atresia of foramina of Magendie and Luschka
+∞
10.4
10
*
G81.9
ICD-10 Finland
Hemiplegia, unspecified
4.7
10.4
34
73
XKD06
NOMESCO Finland
Physiologic investigation of micturition
2.4
10.4
89
383
N17
ICPC
Vertigo/dizziness
1.6
10.4
286
1876
N05AD01
ATC
haloperidol; systemic
2.3
10.3
90
393
G80.1
ICD-10 Finland
Spastic diplegic cerebral palsy
32.6
10.3
13
*
H01BA02
ATC
desmopressin; nasal, systemic, sublingual
3.2
10.2
53
170
G80.2
ICD-10 Finland
Spastic hemiplegic cerebral palsy
23.4
10.2
14
6
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
4.1
10.2
38
93
SPAT1050
SPAT
Extensive neurological examination
2.7
10.2
69
263
RS221
NOMESCO Finland
NA
3.8
10.2
42
113
S12
ICPC
Insect bite/sting
0.4
10.1
53
1181
Z11
ICPC
Compliance/being ill problem
5.2
10.1
30
58
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
3.0
10.1
55
183
TJD20
NOMESCO Finland
Change of gastrostomy tube
5.9
10.1
27
46
PA7BD
NOMESCO Finland
CT angiography of neck and brain
3.7
10.1
42
114
Z3229
NOMESCO Finland
Other healthcare associate professional
1.7
10.0
225
1395
C03CA01
ATC
furosemide; systemic
1.3
10.0
864
7047
S06.2
ICD-10 Finland
Diffuse brain injury
4.5
9.9
34
77
PA2BG
NOMESCO Finland
MRI examination of vessels in the head with high intensity magnet
7.6
9.9
22
29
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
2.3
9.9
92
415
R33
ICD-10 Finland
Retention of urine
1.7
9.8
215
1322
WX402
NOMESCO Finland
General anaesthesia
1.5
9.8
328
2249
I62.1
ICD-10 Finland
Nontraumatic extradural haemorrhage
20.1
9.8
14
7
SPAT1139
SPAT
Nutrition survey
2.2
9.8
97
451
N04AA02
ATC
biperiden; systemic
3.1
9.8
51
165
SPAT1276
SPAT
Outlining of treatment with patient or their family members
2.5
9.8
73
293
WX110
NOMESCO Finland
Local anesthesy
1.3
9.8
1493
13174
ZXD10
NOMESCO Finland
Scheduled procedure
1.3
9.7
912
7521
N03AX16
ATC
pregabalin; oral
1.4
9.7
508
3812
N05AA02
ATC
levomepromazine; systemic
2.2
9.7
96
446
G23.9
ICD-10 Finland
Degenerative disease of basal ganglia, unspecified
13.4
9.7
16
12
XKD00
NOMESCO Finland
Uroflowmetry
1.5
9.6
411
2967
RS313
NOMESCO Finland
NA
7.8
9.6
21
27
B01AC04
ATC
clopidogrel; oral
1.5
9.6
378
2689
G41.0
ICD-10 Finland
Grand mal status epilepticus
15.1
9.5
15
10
L89
ICD-10 Finland
Decubitus ulcer and pressure area
2.8
9.5
58
209
D33.12
ICD-10 Finland
Cerebellum
100.3
9.4
10
*
AAK85
NOMESCO Finland
Replantation of previously excised part of skull cap
100.3
9.4
10
*
SPAT1153
SPAT
Removal of sutures
1.3
9.4
759
6117
AAF45
NOMESCO Finland
Fenestration of intracranial cyst
+∞
9.4
9
*
AAA50
NOMESCO Finland
Intracranial endoscopy
+∞
9.4
9
*
43599
ICD-8 Finland
Transient cerebral ischaemia, Without mention of hypertension
+∞
9.4
9
*
AAW99
NOMESCO Finland
Other intracranial operation
+∞
9.4
9
*
S70.0
ICD-10 Finland
Contusion of hip
2.1
9.4
101
487
C79.31
ICD-10 Finland
Secondary malignant tumor of the cerebellum
12.4
9.3
16
13
G45
ICD-10 Finland
Transient cerebral ischaemic attacks and related syndromes
8.0
9.3
20
25
H55
ICD-10 Finland
Nystagmus and other irregular eye movements
8.0
9.3
20
25
H02AB09
ATC
hydrocortisone; systemic
2.9
9.3
55
194
SAB01
NOMESCO Finland
Restricted oral and dental health check by dental hygienist or dental assistant
1.7
9.2
188
1137
NFB20
NOMESCO Finland
Primary partial prosthetic replacement of hip joint using cement, other or unspecified
2.2
9.2
87
394
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
2.3
9.2
84
374
L01AX03
ATC
temozolomide; systemic
5.5
9.2
26
48
I63.0
ICD-10 Finland
Cerebral infarction due to thrombosis of precerebral arteries
3.1
9.2
47
151
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.6
9.1
232
1490
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.5
9.1
357
2532
G04BD11
ATC
fesoterodine; oral
2.2
9.0
89
414
R74
ICPC
Upper respiratory infection acute
0.7
9.0
255
3635
N06AX03
ATC
mianserin; oral
2.0
9.0
118
616
N05AX12
ATC
aripiprazole; systemic
2.6
8.9
62
241
D33.39
ICD-10 Finland
Benign tumor of the cranial nerves UNS
18.6
8.9
13
7
GBB03
NOMESCO Finland
Percutaneous tracheostomy
18.6
8.9
13
7
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.0
8.9
107
541
9161/1-C71.6
ICD-O-3
Hemangioblastoma of cerebellum, NOS
24.1
8.9
12
5
D33.9
ICD-10 Finland
Benign neoplasm: Central nervous system, unspecified
24.1
8.9
12
5
R40.2
ICD-10 Finland
Coma, unspecified
4.3
8.9
31
72
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
2.7
8.9
60
227
I63.8
ICD-10 Finland
Other cerebral infarction
4.1
8.8
33
82
A86
ICD-10 Finland
Unspecified viral encephalitis
6.8
8.8
21
31
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
2.5
8.8
65
262
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
2.4
8.8
74
319
N05CF01
ATC
zopiclone; oral
1.3
8.8
793
6485
G72.8
ICD-10 Finland
Other specified myopathies
2.9
8.8
52
184
N05BA06
ATC
lorazepam; systemic, sublingual
1.8
8.7
134
741
-2
ICPC
NA
4.7
8.7
28
60
CBK11
NOMESCO Finland
Operation for lagophtalmus with implant
14.1
8.7
14
10
N01
ICPC
Headache
1.7
8.7
186
1143
T36
ICD-10 Finland
Poisoning by systemic antibiotics
2.3
8.7
76
335
H81.4
ICD-10 Finland
Vertigo of central origin
4.5
8.6
29
65
R51
ICD-10 Finland
Headache
2.0
8.6
100
497
H01AC01
ATC
somatropin; parenteral
7.6
8.6
19
25
N05AC02
ATC
thioridazine; oral
2.9
8.6
50
174
S06.9
ICD-10 Finland
Intracranial injury, unspecified
5.5
8.6
24
44
E23.01
ICD-10 Finland
Isolated deficiency of growth hormone
11.6
8.6
15
13
XX7FW
NOMESCO Finland
NA
11.6
8.6
15
13
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
10.0
8.5
16
16
F54
ICD-10 Finland
Psychological and behavioural factors associated with disorders or diseases classified elsewhere
10.0
8.5
16
16
R60.0
ICD-10 Finland
Localized oedema
1.5
8.5
270
1829
C71.99
ICD-10 Finland
Malignant tumor in unspecified localization in the brain other or unspecified histology
20.1
8.5
12
6
N03AG04
ATC
vigabatrin; oral
20.1
8.5
12
6
N06AX21
ATC
duloxetine; oral
1.6
8.4
203
1285
N31.0
ICD-10 Finland
Uninhibited neuropathic bladder, not elsewhere classified
7.3
8.4
19
26
C91.2
ICD-10 Finland
Subacute lymphocytic leukemia
90.3
8.4
9
*
SPAT1296
SPAT
Other function in accordance with occupational therapy nomenclature
3.4
8.4
39
117
N32.82
ICD-10 Finland
Instability of the detrusor vesicae muscle
3.0
8.4
45
150
2152
FHL
Extraction, big brain
12.8
8.4
14
11
P29
ICPC
Psychological sympt/compl other
2.1
8.4
91
441
188
Kela drug reimbursment
Psychosis requiring demanding treatment
4.5
8.3
28
63
SPAT1263
SPAT
Sampling
1.3
8.3
988
8369
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
3.1
8.3
44
145
G96.0
ICD-10 Finland
Cerebrospinal fluid leak
+∞
8.3
8
*
G93.4
ICD-10 Finland
Encephalopathy, unspecified
+∞
8.3
8
*
G80.9
ICD-10 Finland
Cerebral palsy, unspecified
+∞
8.3
8
*
Q03.88
ICD-10 Finland
Other congenital hydrocephalus
+∞
8.3
8
*
G00.3
ICD-10 Finland
Staphylococcal meningitis
+∞
8.3
8
*
G93.6
ICD-10 Finland
Cerebral oedema
+∞
8.3
8
*
C71.6
ICD-10 Finland
Malignant neoplasm: Cerebellum
+∞
8.3
8
*
G90.0
ICD-10 Finland
Idiopathic peripheral autonomic neuropathy
+∞
8.3
8
*
C71.89
ICD-10 Finland
Overall malignant tumor of the brain other or unspecified histology
+∞
8.3
8
*
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
2.2
8.3
84
395
E86
ICD-10 Finland
Volume depletion
2.3
8.3
74
329
F00.20
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type without additional symptoms
3.3
8.3
39
118
3454A
ICD-9 Finland
Epilepsy, Partial epilepsy, with impairment of consciousness[EPILEPSIA GENERALISATA SECUNDARIA]
10.8
8.3
15
14
G45.3
ICD-10 Finland
Amaurosis fugax
14.5
8.2
13
9
102
Kela drug reimbursment
Diabetes insipidus
14.5
8.2
13
9
S22.0
ICD-10 Finland
Fracture of thoracic vertebra
2.6
8.2
56
215
359
Kela drug reimbursment
Mirabegroni
4.1
8.1
30
74
N39.9
ICD-10 Finland
Disorder of urinary system, unspecified
2.9
8.1
48
170
F83
ICD-10 Finland
Mixed specific developmental disorders
5.7
8.1
22
39
F22.0
ICD-10 Finland
Delusional disorder
3.0
8.1
44
148
R41.3
ICD-10 Finland
Other amnesia
2.2
8.1
82
385
F82
ICD-10 Finland
Specific developmental disorder of motor function
8.1
8.1
17
21
N76
ICPC
Neoplasm nervous system unspecified
17.2
8.1
12
7
AAG00
NOMESCO Finland
Stereotactic intracranial biopsy
11.7
8.1
14
12
9560/0-C72.4
ICD-O-3
Schwannoma, NOS, of acoustic nerve
11.7
8.1
14
12
A27
ICPC
Fear of other disease NOS
2.0
8.1
104
539
G40.6
ICD-10 Finland
Grand mal seizures, unspecified (with or without petit mal)
6.8
8.1
19
28
4380A
ICD-9 Finland
Late effects of cerebrovascular disease[SEQUELAE MORBI CEREBROVASCULARIS]
4.8
8.1
25
52
G04BD10
ATC
darifenacin; oral
3.9
8.0
31
80
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
8.9
8.0
16
18
SPAT1138
SPAT
Guidance concerning bowel function
2.9
8.0
46
158
N05CD07
ATC
temazepam; oral
1.4
8.0
332
2383
602
Kela drug reimbursment
Children's severe malnutrition
7.2
7.9
18
25
N06AG02
ATC
moclobemide; oral
2.0
7.9
97
495
R4130
NOMESCO Finland
Speech therapy
2.6
7.9
54
207
ZXC95
NOMESCO Finland
Use of surgical navigator
3.5
7.9
35
102
N06DA04
ATC
galantamine; oral
2.3
7.9
67
290
N05AF03
ATC
chlorprothixene; systemic
2.5
7.9
56
223
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
3.1
7.8
41
135
N12
ICD-10 Finland
Tubulo-interstitial nephritis, not specified as acute or chronic
2.6
7.8
52
200
F01.9
ICD-10 Finland
Vascular dementia, unspecified
2.7
7.8
50
187
D33.10
ICD-10 Finland
Benign pilosytic astrocytoma of brain stem
45.1
7.7
9
*
AAD15
NOMESCO Finland
Evacuation of traumatic intracerebral haematoma
15.0
7.7
12
8
F0019, G301
ICD-10 Finland
NA
3.5
7.7
34
99
N88
ICPC
Epilepsy
5.6
7.7
21
38
G31.0
ICD-10 Finland
Circumscribed brain atrophy
5.6
7.7
21
38
G40.00
ICD-10 Finland
Benign childhood epilepsy with centrotemporal EEG spikes
7.4
7.7
17
23
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
2.3
7.7
69
309
SPAT1279
SPAT
Preparation of immediate hospitalisation
3.1
7.6
40
132
TKC10
NOMESCO Finland
Percutaneous puncture of bladder
2.8
7.6
45
160
I60
ICD-10 Finland
Subarachnoid haemorrhage
18.4
7.6
11
6
D33.3
ICD-10 Finland
Benign neoplasm: Cranial nerves
18.4
7.6
11
6
G40.11
ICD-10 Finland
Simple partial epileptic seizure that develops into a complex partial seizure
8.0
7.6
16
20
I61.8
ICD-10 Finland
Other intracerebral haemorrhage
8.9
7.5
15
17
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.3
7.5
501
3901
RS340
NOMESCO Finland
NA
10.0
7.5
14
14
XKD03
NOMESCO Finland
Urethral pressure profilometry
2.3
7.5
66
293
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.4
7.5
343
2508
N03AX12
ATC
gabapentin; oral
1.4
7.4
313
2249
WX100
NOMESCO Finland
Conjunctival surface anesthesia
0.6
7.4
143
2204
H49.1
ICD-10 Finland
Fourth [trochlear] nerve palsy
4.8
7.4
23
48
N05AL01
ATC
sulpiride; systemic
3.1
7.4
39
129
32400
ICD-8 Finland
Late effects of intracranial abscess or pyogenic infection, Hydrocephalus acquisitus
80.3
7.4
8
*
Q04.6
ICD-10 Finland
Congenital cerebral cysts
80.3
7.4
8
*
PA7RT
NOMESCO Finland
Medical infusion to cerebral artery
80.3
7.4
8
*
H25.8
ICD-10 Finland
Other senile cataract
0.6
7.4
155
2346
AWE00
NOMESCO Finland
Reoperation for deep heamorrhage in surgery of the nervous system
13.4
7.4
12
9
C71.10
ICD-10 Finland
Malignant tumor in frontal lobe without histology
7.7
7.4
16
21
G82.2
ICD-10 Finland
Paraplegia, unspecified
7.7
7.4
16
21
Z63.7
ICD-10 Finland
Other stressful life events affecting family and household
3.6
7.3
31
87
Z29
ICPC
Social problem NOS
2.7
7.3
48
182
N03AX11
ATC
topiramate; oral
2.8
7.3
44
159
J01DB01
ATC
cefalexin; oral
1.3
7.3
1915
17734
G942, I600
ICD-10 Finland
NA
+∞
7.3
7
*
G942, I690
ICD-10 Finland
NA
+∞
7.3
7
*
AAF40
NOMESCO Finland
Shunt of cyst of brain to peritoneum
+∞
7.3
7
*
G90.1
ICD-10 Finland
Familial dysautonomia [Riley-Day]
+∞
7.3
7
*
G941, D431
ICD-10 Finland
NA
+∞
7.3
7
*
3431A
ICD-9 Finland
Infantile cerebral palsy, Hemiplegic
+∞
7.3
7
*
G942, I609
ICD-10 Finland
NA
+∞
7.3
7
*
9560/0-C72.5
ICD-O-3
Schwannoma, NOS, of cranial nerve, NOS
+∞
7.3
7
*
I67.6
ICD-10 Finland
Nonpyogenic thrombosis of intracranial venous system
10.9
7.3
13
12
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.3
7.3
817
6846
N81
ICPC
Injury nervous system other
9.4
7.3
14
15
N19
ICPC
Speech disorder
2.9
7.2
42
147
E22.80
ICD-10 Finland
Central precocious puberty
30.1
7.1
9
*
D33.7
ICD-10 Finland
Benign neoplasm: Other specified parts of central nervous system
30.1
7.1
9
*
D33.14
ICD-10 Finland
Hemangioblastoma and cerebellum
20.1
7.1
10
5
AWW99
NOMESCO Finland
Other reoperation in surgery of the nervous system
20.1
7.1
10
5
S82
ICPC
Naevus/mole
0.6
7.1
106
1730
SPAT1244
SPAT
Occupational therapy
3.2
7.1
34
106
D32.9
ICD-10 Finland
Benign neoplasm: Meninges, unspecified
5.3
7.1
20
38
P85
ICPC
Mental retardation
10.0
7.0
13
13
RL140
NOMESCO Finland
NA
10.0
7.0
13
13
SPAT1307
SPAT
Psychosocial counselling and guidance
1.9
7.0
90
471
N06AA09
ATC
amitriptyline; systemic
1.5
6.9
217
1467
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.4
6.9
342
2535
Z3231
NOMESCO Finland
Registered nurse
1.3
6.9
629
5121
2252A
ICD-9 Finland
Benign neoplasm of brain and other parts of nervous system, Cerebral meninges
13.8
6.9
11
8
L57.0
ICD-10 Finland
Actinic keratosis
0.6
6.9
123
1927
SPAT1224
SPAT
Implementation of speech therapy rehabilitation plan
2.7
6.8
44
164
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
1.8
6.8
108
605
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
1.5
6.8
207
1390
Z60.8
ICD-10 Finland
Other problems related to social environment
6.7
6.8
16
24
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
1.6
6.8
167
1063
G81.0
ICD-10 Finland
Flaccid hemiplegia
10.9
6.8
12
11
XF402
NOMESCO Finland
ECG with work load test
0.6
6.8
113
1799
EBA00
NOMESCO Finland
Extraction of tooth
1.3
6.8
658
5400
C79.39
ICD-10 Finland
Secondary malignant tumor of the meninges, ventricle or other part of the brain
9.3
6.8
13
14
D32.06
ICD-10 Finland
Benign tumor of the meninges os petrosum or clivus area
9.3
6.8
13
14
N06AX26
ATC
vortioxetine; oral
1.9
6.8
92
489
S00.9
ICD-10 Finland
Superficial injury of head, part unspecified
3.1
6.8
34
110
KCV12
NOMESCO Finland
Urinary bladder endoscopic botulin therapy
3.6
6.8
28
78
D33.0
ICD-10 Finland
Benign neoplasm: Brain, supratentorial
40.1
6.8
8
*
F79.9
ICD-10 Finland
Unspecified mental retardation, without mention of impairment of behaviour
40.1
6.8
8
*
Q85.01
ICD-10 Finland
Neurofibromatosis, type 2
40.1
6.8
8
*
RS142
NOMESCO Finland
NA
16.7
6.7
10
6
M41.4
ICD-10 Finland
Neuromuscular scoliosis
22.6
6.7
9
*
2251A
ICD-9 Finland
Benign neoplasm of brain and other parts of nervous system, Cranial nerves
22.6
6.7
9
*
G99.2
ICD-10 Finland
Myelopathy in diseases classified elsewhere
22.6
6.7
9
*
H49.0
ICD-10 Finland
Third [oculomotor] nerve palsy
4.9
6.7
20
41
XA400
NOMESCO Finland
EEG
4.9
6.7
20
41
A10AE04
ATC
insulin glargine; parenteral
1.5
6.6
205
1382
F25.9
ICD-10 Finland
Schizoaffective disorder, unspecified
4.4
6.6
22
50
N31.1
ICD-10 Finland
Reflex neuropathic bladder, not elsewhere classified
4.4
6.6
22
50
R5599
NOMESCO Finland
Other rehabilitation service
2.3
6.6
59
263
G30.0
ICD-10 Finland
Alzheimer disease with early onset
3.1
6.6
34
112
D32.0
ICD-10 Finland
Benign neoplasm: Cerebral meninges
5.5
6.6
18
33
H02.2
ICD-10 Finland
Lagophthalmos
5.5
6.6
18
33
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.5
6.6
254
1794
N03AX15
ATC
zonisamide; oral
12.3
6.6
11
9
E23.2
ICD-10 Finland
Diabetes insipidus
12.3
6.6
11
9
H43.1
ICD-10 Finland
Vitreous haemorrhage
2.3
6.6
56
245
4309X
ICD-9 Finland
Subarachnoid haemorrhage[HAEMORRHAGIA SUBARACHNOIDALIS NUD]
8.7
6.5
13
15
RF420
NOMESCO Finland
NA
3.1
6.5
33
108
RF120
NOMESCO Finland
NA
3.2
6.5
31
97
P99
ICPC
Psychological disorders other
2.7
6.5
42
158
I61.4
ICD-10 Finland
Intracerebral haemorrhage in cerebellum
5.0
6.5
19
38
XX1XW
NOMESCO Finland
Extensive written report from radiologist
2.5
6.5
49
201
N06AB05
ATC
paroxetine; oral
1.8
6.4
101
565
A01
ICPC
Pain general/multiple sites
1.6
6.4
171
1113
D35.30
ICD-10 Finland
Craniopharyngoma
70.0
6.4
7
*
E89.30
ICD-10 Finland
Postprocedural hypopituitarism
70.0
6.4
7
*
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
1.7
6.4
139
857
Z43.5
ICD-10 Finland
Attention to cystostomy
3.9
6.4
24
62
SPAT1240
SPAT
Therapeutic discussion
1.6
6.3
167
1083
I95.1
ICD-10 Finland
Orthostatic hypotension
1.8
6.3
93
511
XX1ZW
NOMESCO Finland
Very extensive written report from radiologist
6.5
6.3
15
23
SPAT1293
SPAT
Other function in accordance with rehabilitation guidance nomenclature
4.6
6.3
20
44
A10BH01
ATC
sitagliptin; oral
1.5
6.3
222
1542
CBH25
NOMESCO Finland
Tarsorrhaphy
18.0
6.3
9
5
N74
ICPC
Malignant neoplasm nervous system
18.0
6.3
9
5
N03AA02
ATC
phenobarbital; systemic
18.0
6.3
9
5
RP120
NOMESCO Finland
NA
18.0
6.3
9
5
G942, I606
ICD-10 Finland
NA
+∞
6.2
6
*
AAB99
NOMESCO Finland
Other excision or destruction of intracranial lesion
+∞
6.2
6
*
D33.15
ICD-10 Finland
Another benign tumor of the cerebellum
+∞
6.2
6
*
Q05.9
ICD-10 Finland
Spina bifida, unspecified
+∞
6.2
6
*
F72.0
ICD-10 Finland
Severe mental retardation, with the statement of no, or minimal, impairment of behaviour
+∞
6.2
6
*
G95.9
ICD-10 Finland
Disease of spinal cord, unspecified
+∞
6.2
6
*
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
0.5
6.2
43
868
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
1.6
6.2
155
993
C71.70
ICD-10 Finland
Malignant tumor of the brainstem without histology
26.7
6.2
8
*
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
1.5
6.2
230
1615
SPAT1260
SPAT
Consultation of another employee
1.3
6.2
396
3061
K59.09
ICD-10 Finland
Constipation, unspecified
1.6
6.2
145
917
B01AC07
ATC
dipyridamole; systemic
1.7
6.2
122
737
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
2.7
6.2
40
151
A41.9
ICD-10 Finland
Sepsis, unspecified
1.8
6.1
95
531
WW200
SPAT
NA
1.5
6.1
177
1175
WX872
NOMESCO Finland
Intensive care
1.7
6.1
113
668
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
1.8
6.1
106
615
S72.1
ICD-10 Finland
Pertrochanteric fracture
2.1
6.1
66
323
F00.9
ICD-10 Finland
Dementia in Alzheimer disease, unspecified
3.4
6.1
27
80
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
1.7
6.1
118
707
XFP96
NOMESCO Finland
Other intraoperative electrophysiological investigation in arhythmia or disturbance of impulse propagation
2.2
6.1
58
267
C71.00
ICD-10 Finland
Malignant tumor of the cerebrum except lobes and ventricles without histology
12.5
6.1
10
8
H50.1
ICD-10 Finland
Divergent concomitant strabismus
3.7
6.1
24
65
I67.3
ICD-10 Finland
Progressive vascular leukoencephalopathy
2.7
6.1
38
143
SPAT1172
SPAT
Guidance concerning hydration
2.0
6.0
72
368
SPAT1014
SPAT
Treatment of eyes
2.2
6.0
55
250

Mortality – FinRegistry

Association

Association between endpoint G6_HYDROCEPH and mortality.

Females

Parameter HR [95% CI] p-value
G6_HYDROCEPH 2.789 [2.54, 3.07] < 0.001
Birth year 0.998 [0.99, 1.01] 0.613

During the follow-up period (1.1.1998 — 31.12.2019), 2969 out of 7243 females with G6_HYDROCEPH died.

Males

Parameter HR [95% CI] p-value
G6_HYDROCEPH 2.805 [2.5, 3.15] < 0.001
Birth year 0.988 [0.98, 1.0] 0.008

During the follow-up period (1.1.1998 — 31.12.2019), 3085 out of 7216 males with G6_HYDROCEPH died.

Mortality risk

Mortality risk for people of age

years, who have G6_HYDROCEPH.

N-year risk Females Males
1 0.225% 0.549%
5 1.497% 3.18%
10 4.065% 7.872%
15 8.242% 15.241%
20 14.097% 25.051%

Relationships between endpoints

Index endpoint: G6_HYDROCEPH – Hydrocephalus

GWS hits: 8

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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