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Neurological diseases

G6_NEURO

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

200053

4. Check minimum number of events

None

200053

5. Include endpoints

204344

6. Filter based on genotype QC (FinnGen only)

204344

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
1
First used in FinnGen datafreeze
DF10

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 204344 112797 91547
Unadjusted period prevalence (%) 39.30 38.45 40.36
Median age at first event (years) 53.43 50.85 56.62

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1569
Matched controls
9551
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
+∞
254.6
287
*
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
16.8
154.4
290
127
G43.9
ICD-10 Finland
Migraine, unspecified
18.6
133.6
241
92
N03AF02
ATC
oxcarbazepine; oral
184.5
131.8
163
6
G47.3
ICD-10 Finland
Sleep apnoea
29.4
131.1
207
49
N03AG01
ATC
valproic acid; systemic, rectal
20.5
129.9
227
78
G40.9
ICD-10 Finland
Epilepsy, unspecified
342.6
127.4
153
*
R56.8
ICD-10 Finland
Other and unspecified convulsions
9.1
113.0
283
226
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
10.6
112.9
259
175
N03AX14
ATC
levetiracetam; systemic
123.1
101.9
130
7
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
782.8
100.9
119
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
8.5
99.1
256
213
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
6.5
91.7
287
319
R51.80
ICD-10 Finland
Headache
4.7
90.1
387
628
G44.2
ICD-10 Finland
Tension-type headache
7.9
86.0
232
205
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
6.5
79.7
248
270
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
10.5
75.2
171
110
N05CD08
ATC
midazolam; nasal, systemic
66.3
74.9
102
10
N05BA09
ATC
clobazam; oral
525.7
68.7
82
*
183
Kela drug reimbursment
Lamotrigin and topiramate
+∞
66.2
77
*
N03AX11
ATC
topiramate; oral
61.5
62.5
86
9
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
+∞
59.3
69
*
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
+∞
54.9
64
*
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
+∞
54.9
64
*
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
5.8
52.6
174
201
C09CA06
ATC
candesartan; oral
9.6
52.1
123
84
N02BE01
ATC
paracetamol; systemic, rectal
2.3
51.9
888
3442
R5140
NOMESCO Finland
Monitoring the use of the aid
25.6
51.8
84
21
AA1AD
NOMESCO Finland
CT of head and brain
4.9
49.4
190
262
G40.4
ICD-10 Finland
Other generalized epilepsy and epileptic syndromes
+∞
48.9
57
*
G40.39
ICD-10 Finland
Other or unspecified generalized epileptic syndromes with atonic, clonic, myoclonic or tonic-clonic seizures
+∞
48.0
56
*
XA800
NOMESCO Finland
Neuropsychological investigation
6.0
46.1
147
161
TAB00
NOMESCO Finland
Lumbar puncture
9.7
45.3
106
71
R4110
NOMESCO Finland
Physiotherapy
2.9
43.5
333
814
G43
ICD-10 Finland
Migraine
5.5
43.4
149
179
C07AB07
ATC
bisoprolol; oral
5.0
43.4
161
212
G43.3
ICD-10 Finland
Complicated migraine
115.5
42.8
55
*
N88
ICPC
Epilepsy
+∞
42.8
50
*
C07AA05
ATC
propranolol; systemic
3.2
40.4
259
558
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.6
40.1
384
1070
N03AX09
ATC
lamotrigine; oral
6.3
39.2
120
124
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
8.6
38.3
95
71
N05BA01
ATC
diazepam; systemic, rectal
4.6
37.2
148
210
G40.19
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
+∞
36.8
43
*
Z2445
NOMESCO Finland
Psychologist
3.2
34.5
217
458
G40.10
ICD-10 Finland
Simple partial seizures
261.6
34.4
42
*
N89
ICPC
Migraine
4.2
34.3
151
237
WX780
NOMESCO Finland
Remote monitoring CPAP
+∞
33.3
39
*
A02BC02
ATC
pantoprazole; systemic
2.4
33.2
367
1088
M03BX02
ATC
tizanidine; oral
2.6
33.1
291
762
N02CC04
ATC
rizatriptan; oral
11.3
33.1
71
40
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.6
32.4
289
762
Z2221
NOMESCO Finland
Medical doctor
2.4
31.9
335
967
ZXE10
NOMESCO Finland
More than one and less than three hours
2.3
31.7
385
1194
A03FA01
ATC
metoclopramide; systemic, rectal
4.4
31.5
130
191
Z3226
NOMESCO Finland
Physiotherapist
2.5
31.3
292
788
G43.8
ICD-10 Finland
Other migraine
36.0
30.9
46
8
N06AX11
ATC
mirtazapine; oral
2.7
30.3
253
641
N03AG04
ATC
vigabatrin; oral
+∞
29.9
35
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.2
29.5
385
1230
Z3231
NOMESCO Finland
Registered nurse
2.1
29.5
471
1643
N03AX12
ATC
gabapentin; oral
7.2
29.4
81
72
WX723
NOMESCO Finland
CPAP therapy
223.1
29.3
36
*
G40.89
ICD-10 Finland
Other epilepsy
+∞
29.1
34
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.9
28.5
199
449
R53
ICD-10 Finland
Malaise and fatigue
2.7
28.3
235
591
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
3.1
26.9
174
373
3007
Kela drug reimbursment
Erenumab and fremanezumab
203.9
26.7
33
*
N03AX18
ATC
lacosamide; systemic
203.9
26.7
33
*
G80.1
ICD-10 Finland
Spastic diplegic cerebral palsy
+∞
26.5
31
*
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
+∞
26.5
31
*
N05AH04
ATC
quetiapine; oral
2.3
26.0
284
827
G51.0
ICD-10 Finland
Bell palsy
197.6
25.9
32
*
R42
ICD-10 Finland
Dizziness and giddiness
3.3
25.9
151
300
R4120
NOMESCO Finland
Occupational therapy
4.2
25.8
110
167
G80.2
ICD-10 Finland
Spastic hemiplegic cerebral palsy
+∞
25.6
30
*
G97.0
ICD-10 Finland
Cerebrospinal fluid leak from spinal puncture
+∞
25.6
30
*
N02CC07
ATC
frovatriptan; oral
16.9
25.4
46
17
TPH04
NOMESCO Finland
Cathetrisation of vein
2.6
25.2
212
535
N03AX16
ATC
pregabalin; oral
4.2
25.2
108
165
XF400
NOMESCO Finland
ECG with 12 standard connections
2.6
24.6
217
563
G47.9
ICD-10 Finland
Sleep disorder, unspecified
11.8
24.5
51
27
Z2446
NOMESCO Finland
Social worker
2.5
24.0
223
595
G40
ICD-10 Finland
Epilepsy
+∞
23.9
28
*
181
Kela drug reimbursment
Retigabine and vigabatrin
+∞
23.9
28
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.2
23.8
289
882
ZXE00
NOMESCO Finland
One hour or less
1.9
23.4
501
1917
N06AB10
ATC
escitalopram; oral
2.2
23.4
283
862
ZY010
NOMESCO Finland
Hospital outpatient
2.6
23.4
204
525
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.3
23.4
267
792
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
4.5
23.2
92
130
G40.09
ICD-10 Finland
Other or unspecified partial (focal) idiopathic epilepsy or epileptic syndrome with local onset
+∞
23.0
27
*
G40.11
ICD-10 Finland
Simple partial epileptic seizure that develops into a complex partial seizure
+∞
23.0
27
*
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
9.5
23.0
53
35
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.5
22.8
211
561
WX408
NOMESCO Finland
General anesthesy, balanced
2.0
22.7
387
1360
Z01.8
ICD-10 Finland
Other specified special examinations
2.3
22.6
245
706
G41.9
ICD-10 Finland
Status epilepticus, unspecified
174.0
22.5
28
*
M01AE01
ATC
ibuprofen; systemic, rectal
1.7
22.3
1016
4909
N01
ICPC
Headache
1.8
22.3
557
2240
ZXD05
NOMESCO Finland
Urgent procedure
2.1
22.2
324
1070
N02CC06
ATC
eletriptan; oral
12.2
22.0
45
23
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
11.7
21.7
45
24
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.8
21.6
467
1783
ZXE20
NOMESCO Finland
More than three and less than five hours
2.7
21.1
170
418
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
37.2
20.4
30
5
N05BA04
ATC
oxazepam; oral
2.6
20.3
168
419
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.0
19.9
290
953
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.4
19.7
108
204
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
2.7
19.7
153
367
G91.1
ICD-10 Finland
Obstructive hydrocephalus
+∞
19.6
23
*
M79.6
ICD-10 Finland
Pain in limb
1.9
19.6
340
1196
R55
ICD-10 Finland
Syncope and collapse
3.2
19.1
114
229
G25.8
ICD-10 Finland
Other specified extrapyramidal and movement disorders
+∞
18.8
22
*
Z3229
NOMESCO Finland
Other healthcare associate professional
2.7
18.8
142
336
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
2.5
18.6
163
419
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.1
18.5
240
750
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
3.3
18.1
103
199
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
7.8
18.0
46
37
N02CC03
ATC
zolmitriptan; nasal, oral
6.8
17.9
50
46
N03AX22
ATC
perampanel; oral
+∞
17.9
21
*
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
+∞
17.9
21
*
N02CD01
ATC
erenumab; parenteral
135.7
17.5
22
*
N05AX08
ATC
risperidone; systemic
2.8
17.4
125
286
RT150
NOMESCO Finland
NA
18.6
17.3
30
10
N03AF01
ATC
carbamazepine; oral, rectal
32.2
17.3
26
5
R51
ICD-10 Finland
Headache
3.1
17.2
106
219
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.7
17.2
83
142
S06.0
ICD-10 Finland
Concussion
2.1
17.1
236
754
R06.5
ICD-10 Finland
Mouth breathing
3.0
17.0
110
234
ZXD10
NOMESCO Finland
Scheduled procedure
1.7
16.7
409
1602
A02BC05
ATC
esomeprazole; systemic
2.3
16.6
169
469
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.9
16.6
271
926
WX892
NOMESCO Finland
Monitored bed care
3.0
16.4
107
228
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
2.1
16.2
213
666
G40.00
ICD-10 Finland
Benign childhood epilepsy with centrotemporal EEG spikes
+∞
16.2
19
*
L01
ICPC
Neck symptom/complaint
2.2
16.1
194
585
F51.0
ICD-10 Finland
Nonorganic insomnia
2.4
15.8
148
394
N02CD03
ATC
fremanezumab; systemic
123.2
15.8
20
*
N06AB03
ATC
fluoxetine; oral
2.4
15.5
146
389
G56.0
ICD-10 Finland
Carpal tunnel syndrome
10.0
15.4
34
21
TAB22
NOMESCO Finland
Stoppin epidural fluid escape with coagulated blood
+∞
15.3
18
*
G80.9
ICD-10 Finland
Cerebral palsy, unspecified
+∞
15.3
18
*
G40.21
ICD-10 Finland
Partial epileptic seizure with cloudiness and automatism
+∞
15.3
18
*
N03AX15
ATC
zonisamide; oral
+∞
15.3
18
*
G47.4
ICD-10 Finland
Narcolepsy and cataplexy
+∞
15.3
18
*
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
1.9
15.3
256
879
G44.8
ICD-10 Finland
Other specified headache syndromes
12.0
15.3
31
16
ZXA05
NOMESCO Finland
Left side
2.3
15.3
157
439
AA7AA
NOMESCO Finland
Liquor cerebri shunt X-ray examinatin without contrast
117.0
15.0
19
*
AAF20
NOMESCO Finland
Revision of shunt of ventricle of brain
117.0
15.0
19
*
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
5.2
14.8
50
60
F90.0
ICD-10 Finland
Disturbance of activity and attention
2.1
14.7
180
546
N02AX02
ATC
tramadol; systemic, rectal
2.2
14.5
167
492
A02BC01
ATC
omeprazole; systemic
2.4
14.5
133
351
XF404
NOMESCO Finland
Ambulatory ECG
3.2
14.5
85
170
M25.5
ICD-10 Finland
Pain in joint
1.9
14.4
254
888
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.1
14.4
180
550
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.3
14.4
150
421
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
3.1
14.3
85
172
N06AX16
ATC
venlafaxine; oral
2.4
14.3
134
358
N03AE01
ATC
clonazepam; systemic
7.4
14.2
37
31
L28
ICPC
Limited function/disability (L)
2.9
14.2
98
218
M01AE03
ATC
ketoprofen; systemic, rectal
2.9
14.2
98
218
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
8.4
14.1
34
25
WX402
NOMESCO Finland
General anaesthesia
2.0
14.1
221
740
F93.89
ICD-10 Finland
Other childhood emotional disorders
3.0
14.1
88
184
M01AE02
ATC
naproxen; oral, rectal
1.5
14.1
877
4329
N06AX21
ATC
duloxetine; oral
3.7
13.9
67
115
R11
ICD-10 Finland
Nausea and vomiting
2.3
13.8
147
417
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
6.1
13.8
41
42
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
2.5
13.8
120
308
Z31.5
ICD-10 Finland
Genetic counselling
2.7
13.7
102
237
G35
ICD-10 Finland
Multiple sclerosis
+∞
13.6
16
*
G91.9
ICD-10 Finland
Hydrocephalus, unspecified
+∞
13.6
16
*
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
9.1
13.5
31
21
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.4
13.4
126
337
G54.0
ICD-10 Finland
Brachial plexus disorders
25.9
13.4
21
5
N02AJ06
ATC
codeine and paracetamol; systemic
1.8
13.4
297
1120
P06
ICPC
Sleep disturbance
2.2
13.4
157
467
M03BC01
ATC
orphenadrine (citrate); systemic
2.7
13.4
98
228
P85
ICPC
Mental retardation
8.3
13.2
32
24
Z71.8
ICD-10 Finland
Other specified counselling
1.7
13.2
357
1429
SPAT1240
SPAT
Therapeutic discussion
1.8
12.9
238
846
G47.2
ICD-10 Finland
Disorders of the sleep-wake schedule
+∞
12.8
15
*
N03AX23
ATC
brivaracetam; systemic
+∞
12.8
15
*
G25.0
ICD-10 Finland
Essential tremor
15.8
12.7
23
9
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
2.9
12.6
82
176
M54.5
ICD-10 Finland
Low back pain
1.8
12.5
243
875
X59
ICD-10 Finland
Exposure to unspecified factor
1.8
12.5
271
1013
R5599
NOMESCO Finland
Other rehabilitation service
3.8
12.5
56
91
WX704
NOMESCO Finland
Intubation
3.2
12.4
71
140
Z63.7
ICD-10 Finland
Other stressful life events affecting family and household
2.8
12.4
89
204
M41.4
ICD-10 Finland
Neuromuscular scoliosis
36.9
12.4
18
*
L11
ICPC
Wrist symptom/complaint
1.9
12.3
215
747
F83
ICD-10 Finland
Mixed specific developmental disorders
2.8
12.2
87
198
J01DB01
ATC
cefalexin; oral
1.5
12.2
1026
5324
R62.0
ICD-10 Finland
Delayed milestone
2.7
12.2
90
209
N06BA04
ATC
methylphenidate; oral
2.2
12.1
133
382
R07.4
ICD-10 Finland
Chest pain, unspecified
2.1
12.1
154
473
M01AB05
ATC
diclofenac; systemic, rectal
1.8
12.0
256
949
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.3
11.9
65
123
TJD20
NOMESCO Finland
Change of gastrostomy tube
8.7
11.9
28
20
G40.33
ICD-10 Finland
Juvenile absence epilepsy
+∞
11.9
14
*
G91.0
ICD-10 Finland
Communicating hydrocephalus
+∞
11.9
14
*
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.0
11.9
175
569
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.5
11.8
921
4687
XG466
NOMESCO Finland
Sleep oxymetry
34.8
11.6
17
*
WX110
NOMESCO Finland
Local anesthesy
1.5
11.6
1037
5422
N02CC05
ATC
almotriptan; oral
6.6
11.6
32
30
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
3.5
11.5
58
104
T36
ICD-10 Finland
Poisoning by systemic antibiotics
2.9
11.5
77
169
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
2.3
11.5
115
316
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
3.5
11.4
58
105
G44.0
ICD-10 Finland
Cluster headache syndrome
19.5
11.3
19
6
JDB10
NOMESCO Finland
Percutaneous gastrostomy
9.6
11.3
25
16
N06AB06
ATC
sertraline; oral
2.0
11.3
154
488
SPAT1229
SPAT
Assessment of need for aid
5.4
11.3
36
41
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
3.3
11.2
61
115
N06AX12
ATC
bupropion; oral
2.4
11.2
106
283
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
2.3
11.2
111
304
XF600
NOMESCO Finland
Bloodpressure measurement
2.2
11.2
129
381
XCK00
NOMESCO Finland
Perimetry
4.6
11.2
41
55
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.8
11.1
234
863
G04.9
ICD-10 Finland
Encephalitis, myelitis and encephalomyelitis, unspecified
+∞
11.1
13
*
N03AD01
ATC
ethosuximide; oral
+∞
11.1
13
*
ADB00
NOMESCO Finland
Implantation of vagus nerve stimulating device
+∞
11.1
13
*
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.5
10.9
89
221
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.4
10.9
100
265
RS222
NOMESCO Finland
NA
6.9
10.8
29
26
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.8
10.7
199
706
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
3.1
10.7
63
126
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
2.2
10.6
116
332
R20.2
ICD-10 Finland
Paraesthesia of skin
3.9
10.6
46
73
SPAT1283
SPAT
Restricted health certificate
1.5
10.6
448
1989
H53.4
ICD-10 Finland
Visual field defects
18.5
10.6
18
6
L03
ICPC
Low back symptom/complaint
1.7
10.6
277
1091
K30
ICD-10 Finland
Functional dyspepsia
2.9
10.4
67
144
E66.00
ICD-10 Finland
Metabolic syndrome
6.2
10.4
30
30
G40.30
ICD-10 Finland
Benign myoclonic eplilepsy in infancy
+∞
10.2
12
*
G80.0
ICD-10 Finland
Spastic quadriplegic cerebral palsy
+∞
10.2
12
*
G81.9
ICD-10 Finland
Hemiplegia, unspecified
+∞
10.2
12
*
M53.1
ICD-10 Finland
Cervicobrachial syndrome
3.0
10.2
62
129
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
10.8
10.1
21
12
IGY02
NOMESCO Finland
Psychiatric monitoring contact
2.4
10.0
87
224
N06BA07
ATC
modafinil; oral
43.0
10.0
14
*
J01AA02
ATC
doxycycline; systemic
1.6
10.0
344
1455
N05CF01
ATC
zopiclone; oral
2.8
9.9
67
148
SPAT1249
SPAT
Treatment-related counselling outside office
1.5
9.9
505
2328
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
3.9
9.8
43
69
ICZ03
NOMESCO Finland
Participation in compiling a psychiatric treatment plan
2.1
9.8
121
368
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.5
9.8
80
200
XF402
NOMESCO Finland
ECG with work load test
3.4
9.7
50
92
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
3.2
9.6
53
102
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.2
9.6
107
310
F81.8
ICD-10 Finland
Other developmental disorders of scholastic skills
4.6
9.6
35
47
F82
ICD-10 Finland
Specific developmental disorder of motor function
2.8
9.5
65
145
J01CE02
ATC
phenoxymethylpenicillin; oral
1.4
9.5
909
4715
M03BX01
ATC
baclofen; systemic
23.0
9.4
15
*
L09
ICPC
Arm symptom/complaint
2.4
9.4
87
230
E66.8
ICD-10 Finland
Other obesity
4.4
9.4
36
51
A04
ICPC
Weakness/tiredness general
1.6
9.4
248
977
G56.2
ICD-10 Finland
Lesion of ulnar nerve
14.9
9.4
17
7
G80.3
ICD-10 Finland
Dyskinetic cerebral palsy
+∞
9.4
11
*
G40.6
ICD-10 Finland
Grand mal seizures, unspecified (with or without petit mal)
+∞
9.4
11
*
282
Kela drug reimbursment
Sodium oxybat
+∞
9.4
11
*
G40.36
ICD-10 Finland
Juvenile myoclonic epilepsy [impulsive petit mal]
+∞
9.4
11
*
G93.0
ICD-10 Finland
Cerebral cysts
+∞
9.4
11
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.6
9.3
288
1184
ACC51
NOMESCO Finland
Release of median nerve
28.6
9.3
14
*
H02AB06
ATC
prednisolone; systemic
1.6
9.3
323
1365
R4190
NOMESCO Finland
Nutritional therapy
2.2
9.3
105
308
M03BC51
ATC
orphenadrine, combinations; systemic
2.5
9.2
74
183
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
2.1
9.2
105
309
R2110
NOMESCO Finland
Giving the first information
3.5
9.2
45
80
C03CA01
ATC
furosemide; systemic
3.3
9.2
50
95
N05AH03
ATC
olanzapine; systemic
2.1
9.2
109
327
G72.8
ICD-10 Finland
Other specified myopathies
73.6
9.2
12
*
J96.1
ICD-10 Finland
Chronic respiratory failure
73.6
9.2
12
*
AEA50
NOMESCO Finland
Adjustment of implanted neurostimulator
73.6
9.2
12
*
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
2.3
9.2
88
238
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.6
9.2
270
1095
C07AB02
ATC
metoprolol; systemic
3.6
9.1
43
74
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
13.1
8.9
17
8
P01
ICPC
Feeling anxious/nervous/tense
1.5
8.9
365
1600
R1210
NOMESCO Finland
Medical assessment of need and possibilities to rehabilitation
4.1
8.9
36
54
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.4
8.9
550
2623
R4150
NOMESCO Finland
Neuropsychological rehabilitation
18.4
8.9
15
5
R03AC02
ATC
salbutamol; inhalant
1.4
8.8
685
3403
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
5.1
8.8
29
35
H03AA01
ATC
levothyroxine sodium; systemic
2.4
8.8
79
208
XA400
NOMESCO Finland
EEG
8.8
8.8
20
14
RS211
NOMESCO Finland
NA
6.4
8.7
24
23
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
8.7
659
3256
ZXA10
NOMESCO Finland
Bilateral
1.7
8.7
186
690
G93.3
ICD-10 Finland
Postviral fatigue syndrome
21.5
8.7
14
*
M79.1
ICD-10 Finland
Myalgia
2.1
8.7
109
335
NE1AA
NOMESCO Finland
Pelvis X-ray examination
3.5
8.6
42
75
M01AG02
ATC
tolfenamic acid; oral, rectal
3.3
8.6
45
85
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
7.1
8.6
22
19
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.8
8.5
150
522
R1250
NOMESCO Finland
Evaluation of functional capability
4.6
8.5
31
42
G37.9
ICD-10 Finland
Demyelinating disease of central nervous system, unspecified
+∞
8.5
10
*
109
Kela drug reimbursment
Multiple sclerosis
+∞
8.5
10
*
N03AF03
ATC
rufinamide; oral
+∞
8.5
10
*
RT274
NOMESCO Finland
NA
+∞
8.5
10
*
G71.9
ICD-10 Finland
Primary disorder of muscle, unspecified
+∞
8.5
10
*
214
Kela drug reimbursment
Severe and chronic narcolepsy
+∞
8.5
10
*
AAJ20
NOMESCO Finland
Excision of epileptic focus
+∞
8.5
10
*
F81.3
ICD-10 Finland
Mixed disorder of scholastic skills
3.9
8.5
36
57
S93.4
ICD-10 Finland
Sprain and strain of ankle
1.6
8.5
246
994
D43.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, supratentorial
36.8
8.4
12
*
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
3.7
8.3
38
64
L02
ICPC
Back symptom/complaint
1.7
8.3
170
622
F43.8
ICD-10 Finland
Other reactions to severe stress
3.4
8.3
42
77
B01AA03
ATC
warfarin; systemic
4.3
8.3
32
46
SPAT1307
SPAT
Psychosocial counselling and guidance
1.6
8.2
256
1049
R1220
NOMESCO Finland
Psychological examination of need and possibilities to rehabilitation
3.0
8.2
50
104
P03
ICPC
Feeling depressed
1.6
8.2
259
1067
S18
ICPC
Laceration/cut
1.4
8.2
417
1908
N06AB04
ATC
citalopram; systemic
2.6
8.2
61
145
RL140
NOMESCO Finland
NA
10.4
8.2
17
10
NA1AD
NOMESCO Finland
Cervical spine CT examination
2.9
8.2
51
109
M01AH05
ATC
etoricoxib; oral
1.6
8.1
239
969
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
5.2
8.0
26
31
I10
ICD-10 Finland
Essential (primary) hypertension
3.1
8.0
45
89
ZYC01
NOMESCO Finland
Remote contact by phone
2.1
8.0
92
272
H66.0
ICD-10 Finland
Acute suppurative otitis media
1.5
8.0
379
1710
EMB10
NOMESCO Finland
Tonsillectomy
1.8
8.0
137
474
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.3
7.9
77
210
N05AA02
ATC
levomepromazine; systemic
4.5
7.9
29
40
RS310
NOMESCO Finland
NA
8.5
7.8
18
13
SPAT1389
SPAT
Visit based on need for special support
1.7
7.8
184
702
N06CA01
ATC
amitriptyline and psycholeptics; systemic
6.2
7.8
22
22
FM2CE
NOMESCO Finland
NA
2.2
7.8
82
234
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.2
7.8
81
228
XX4AW
NOMESCO Finland
NA
4.4
7.7
29
41
KMAK
NOMESCO Finland
NA
1.5
7.7
283
1207
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.4
7.7
537
2600
G81.1
ICD-10 Finland
Spastic hemiplegia
+∞
7.7
9
*
D33.05
ICD-10 Finland
Other lateral benign tumor in temporal lobe
+∞
7.7
9
*
199
Kela drug reimbursment
Rufinamide
+∞
7.7
9
*
G60.0
ICD-10 Finland
Hereditary motor and sensory neuropathy
+∞
7.7
9
*
G40.2
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
+∞
7.7
9
*
G40.35
ICD-10 Finland
Juvenile absence epilepsy
+∞
7.7
9
*
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
3.0
7.6
44
90
M54.4
ICD-10 Finland
Lumbago with sciatica
2.5
7.6
60
148
N18
ICPC
Paralysis/weakness
61.2
7.5
10
*
G03.9
ICD-10 Finland
Meningitis, unspecified
61.2
7.5
10
*
AAF25
NOMESCO Finland
Removal of shunt of ventricle of brain
61.2
7.5
10
*
R90.8
ICD-10 Finland
Other abnormal findings on diagnostic imaging of central nervous system
9.8
7.5
16
10
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
2.2
7.5
80
230
M03AX01
ATC
botulinum toxin; parenteral
15.9
7.4
13
5
M53.0
ICD-10 Finland
Cervicocranial syndrome
2.8
7.4
49
107
N06AX26
ATC
vortioxetine; oral
2.1
7.4
90
273
ZXE17
NOMESCO Finland
Procedure duration 150 to 179 minutes
2.9
7.4
46
98
IAB07
NOMESCO Finland
Consultation concerning a patient with self-harm intention
5.1
7.4
24
29
N29
ICPC
Neurological sympt/complt other
5.1
7.4
24
29
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.6
7.4
237
978
IGY99
NOMESCO Finland
Other psychiatric treatment contact
2.1
7.4
81
236
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.8
7.3
47
103
N17
ICPC
Vertigo/dizziness
1.8
7.3
131
458
ICB03
NOMESCO Finland
Psychiatric treatment plan, monitoring
2.7
7.3
50
114
H52.0
ICD-10 Finland
Hypermetropia
2.4
7.3
66
174
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
2.0
7.3
93
289
F51.9
ICD-10 Finland
Nonorganic sleep disorder, unspecified
3.6
7.3
33
56
P76
ICPC
Depressive disorder
1.9
7.3
115
386
SPAT1262
SPAT
Handing over of treatment supplies
2.2
7.2
78
225
R06.0
ICD-10 Finland
Dyspnoea
1.7
7.2
155
574
ICB02
NOMESCO Finland
Psychiatric treatment plan, extended/prolonged
3.4
7.2
35
63
S60.2
ICD-10 Finland
Contusion of other parts of wrist and hand
2.0
7.2
94
294
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
2.0
7.2
96
303
M54.2
ICD-10 Finland
Cervicalgia
2.9
7.2
45
97
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
2.3
7.2
70
192
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.4
7.1
582
2886
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
1.9
7.1
105
344
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.5
7.1
284
1234
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
1.9
7.1
103
337
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.7
7.1
49
113
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.9
7.0
106
349
T82
ICPC
Obesity
3.1
7.0
40
81
C08DA01
ATC
verapamil; systemic
13.3
7.0
13
6
G57.3
ICD-10 Finland
Lesion of lateral popliteal nerve
22.4
7.0
11
*
SPAT1050
SPAT
Extensive neurological examination
4.0
6.9
28
43
IBA04
NOMESCO Finland
Extensive initial psychiatric evaluation
2.2
6.9
69
193
R52.9
ICD-10 Finland
Pain, unspecified
2.1
6.9
80
239
N28
ICPC
Limited function/disability (N)
8.2
6.9
16
12
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
6.9
248
1053
R01AD12
ATC
fluticasone furoate; nasal
1.4
6.9
362
1662
R00.2
ICD-10 Finland
Palpitations
2.2
6.8
68
189
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
2.0
6.8
93
295
AAG50
NOMESCO Finland
Stereotactic intracranial radiotherapy
30.6
6.8
10
*
RT190
NOMESCO Finland
NA
+∞
6.8
8
*
N07XX04
ATC
sodium oxybate; oral
+∞
6.8
8
*
N03AX17
ATC
stiripentol; oral
+∞
6.8
8
*
3AX01
NOMESCO Finland
NA
+∞
6.8
8
*
AA10D
NOMESCO Finland
NA
+∞
6.8
8
*
G80.8
ICD-10 Finland
Other cerebral palsy
+∞
6.8
8
*
AAF99
NOMESCO Finland
Other shunt operation on ventricle of brain or intracerebral cyst
+∞
6.8
8
*
G40.1
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
+∞
6.8
8
*
Q04.3
ICD-10 Finland
Other reduction deformities of brain
+∞
6.8
8
*
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
4.2
6.8
26
38
W10
ICD-10 Finland
Fall on and from stairs and steps
2.8
6.8
43
94
RS140
NOMESCO Finland
NA
5.0
6.7
22
27
G55.1*M51.1
ICD-10 Finland
Compression of nerve roots and nerve plexus in disc diseases in the lumbar region and other regions
14.7
6.7
12
5
N05CF02
ATC
zolpidem; oral
2.7
6.7
46
105
H52.2
ICD-10 Finland
Astigmatism
2.5
6.7
54
134
ZXE30
NOMESCO Finland
More than five and less than seven hours
2.2
6.7
65
180
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
3.3
6.7
34
64
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
3.3
6.7
34
64
WX730
NOMESCO Finland
Conventional respirator
4.3
6.6
25
36
UDC00
NOMESCO Finland
Ear microscopy
1.7
6.6
132
480
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
11.4
6.6
13
7
J35.1
ICD-10 Finland
Hypertrophy of tonsils
1.9
6.6
97
318
R50.9
ICD-10 Finland
Fever, unspecified
1.5
6.5
252
1084
TLC00
NOMESCO Finland
Insertion of intrauterine device
3.6
6.5
30
52
H53.1
ICD-10 Finland
Subjective visual disturbances
2.7
6.5
45
104
N99
ICPC
Neurological disease other
16.8
6.5
11
*
H47.1
ICD-10 Finland
Papilloedema, unspecified
16.8
6.5
11
*
E66.01
ICD-10 Finland
Obesity due to excess calories
2.2
6.5
68
195
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.2
6.4
65
182
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.4
6.4
53
135
AA1BM
NOMESCO Finland
MRI examination of brain with 3 Tesla magnet
6.5
6.4
17
16
R1260
NOMESCO Finland
Evaluation of communicative skills
3.5
6.4
30
53
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
2.2
6.4
67
191
J02.9
ICD-10 Finland
Acute pharyngitis, unspecified
1.6
6.4
159
616
TPH07
NOMESCO Finland
Cathetrisation of artery
2.0
6.4
84
265
X44
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
3.3
6.3
32
60
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.7
6.3
131
482
SPAT1377
SPAT
Polysomnography
4.2
6.3
24
35
R52.2
ICD-10 Finland
Other chronic pain
4.2
6.3
24
35
PA6BG
NOMESCO Finland
MRI examination of neck vasculature with high intensity magnet
12.3
6.3
12
6
N05AX12
ATC
aripiprazole; systemic
2.0
6.3
87
278
R4130
NOMESCO Finland
Speech therapy
2.7
6.3
43
98
61
HP
Catheterization and pressure measurement of the left side of the heart
5.1
6.3
20
24
SPAT1153
SPAT
Removal of sutures
1.6
6.3
193
787
F70.1
ICD-10 Finland
Mild mental retardation, Significant impairment of behaviour requiring attention or treatment
7.7
6.3
15
12
R10.0
ICD-10 Finland
Acute abdomen
3.1
6.3
35
70
F41.0
ICD-10 Finland
Panic disorder [episodic paroxysmal anxiety]
2.5
6.3
49
121
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
10.0
6.2
13
8
J45.9
ICD-10 Finland
Asthma, unspecified
1.5
6.2
197
811
ICC04
NOMESCO Finland
Psychiatric treatment plan, permanent discontinuation
2.1
6.2
69
203
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
6.1
6.2
17
17
WX002
NOMESCO Finland
Sedation and analgesia
1.8
6.2
108
378
DFF00
NOMESCO Finland
Pure tone audiometry
2.3
6.1
57
155
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.2
6.1
65
186
SPAT1215
SPAT
Assessment of need for medical rehabilitation
2.5
6.1
48
119
IFA01
NOMESCO Finland
Psychiatric pharmacotherapy plan, not specified
2.4
6.1
51
131
U07
ICPC
Urine symptom/complaint other
2.9
6.1
38
82
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.0
6.0
76
236
AAF50
NOMESCO Finland
Third ventriculostomy
27.5
6.0
9
*
K04.08
ICD-10 Finland
Other specified pulpit
2.0
6.0
79
248

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: G6_NEURO – Neurological diseases

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).