No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersNone 0 out of 7 registries used, show all original rules. |
0 |
4. Check minimum number of eventsNone |
0 |
5. Include endpoints |
11384 |
6. Filter based on genotype QC (FinnGen only) |
11384 |
Control definitions (FinnGen only)
- Control exclude
- THYROID_DISORDER_IBD
Extra metadata
- First used in FinnGen datafreeze
- DF2
Thyrotoxicosis
based on the number of shared cases.
Similar with more cases:
Similar with less cases:
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 77269 | 61676 | 14979 |
| Only index persons | 67659 | 54737 | 12922 |
| Unadjusted period prevalence (%) | |||
| Whole population | 1.50 | 1.77 | 0.42 |
| Only index persons | 1.72 | 2.01 | 0.49 |
| Median age at first event (years) | |||
| Whole population | 54.48 | 53.92 | 57.07 |
| Only index persons | 52.97 | 52.26 | 55.95 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 11384 | 9028 | 2356 |
| Unadjusted period prevalence (%) | 2.66 | 3.08 | 1.04 |
| Median age at first event (years) | 52.46 | 50.64 | 59.41 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 10169
- Matched controls
- 101701
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
E05.89
ICD-10 Finland
Other thyrotoxicosis
699.3
323.0
404
6
C07AB07
ATC
bisoprolol; oral
2.3
323.0
5152
31812
E05.9
ICD-10 Finland
Thyrotoxicosis, unspecified
1697.2
323.0
4487
47
104
Kela drug reimbursment
Thyroid insufficiency
7.6
323.0
2376
3910
E89.00
ICD-10 Finland
Postirradiation hypothyroidism
222.4
323.0
1039
52
XX7CT
NOMESCO Finland
Radioiodine therapy of thydoid tissue
39.5
323.0
670
181
BA1AE
NOMESCO Finland
Thyroiid ultrasound examination
15.2
323.0
664
465
T85
ICPC
Hyperthyroidism/thyrotoxicosis
45.9
323.0
402
91
E89.01
ICD-10 Finland
Postsurgical hypothyroidism
24.9
323.0
1042
464
E05.0
ICD-10 Finland
Thyrotoxicosis with diffuse goitre
6332.4
323.0
5205
15
E05
ICD-10 Finland
Thyrotoxicosis [hyperthyroidism]
182.2
323.0
1076
66
H03AA01
ATC
levothyroxine sodium; systemic
7.9
323.0
6144
16450
H03BB01
ATC
carbimazole; oral
1441.7
323.0
6979
154
E05.80
ICD-10 Finland
Subacute thyrotoxicosis
292.2
323.0
880
33
BAA60
NOMESCO Finland
Total thyroidectomy
21.9
323.0
1467
775
H06.2*E05.9
ICD-10 Finland
Dysthyroid exophthalmos
+∞
323.0
678
*
E05.2
ICD-10 Finland
Thyrotoxicosis with toxic multinodular goitre
1021.1
323.0
1633
19
C07AA05
ATC
propranolol; systemic
3.6
323.0
3461
12615
24210
ICD-8 Finland
Thyrotoxicosis with or without goitre, Toxic nodular goitre
+∞
308.9
295
*
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
2.9
275.3
1945
7623
E05.1
ICD-10 Finland
Thyrotoxicosis with toxic single thyroid nodule
+∞
273.1
261
*
H06.2
ICD-10 Finland
Dysthyroid exophthalmos
2417.7
255.0
246
*
E03.2
ICD-10 Finland
Hypothyroidism due to medicaments and other exogenous substances
42.2
237.3
299
73
EP1AE
NOMESCO Finland
Neck ultrasound examination
3.9
214.0
969
2685
H062, E050
ICD-10 Finland
NA
+∞
203.8
195
*
C01BD01
ATC
amiodarone; systemic
6.4
184.6
512
834
24209
ICD-8 Finland
Thyrotoxicosis with or without goitre, Cum struma diffuse NUD
+∞
183.9
176
*
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
8.4
170.2
391
482
2420A
ICD-9 Finland
Thyrotoxicosis with or without goitre, Toxic diffuse goitre
+∞
168.2
161
*
E03.89
ICD-10 Finland
Other specified hypothyroidism
4.3
163.5
645
1563
T86
ICPC
Hypothyroidism/myxoedema
3.8
146.4
670
1854
24200
ICD-8 Finland
Thyrotoxicosis with or without goitre, Cum struma diffusa et exophthalmo. Morbus Basedowi
+∞
145.1
139
*
H03BA02
ATC
propylthiouracil; oral
+∞
142.0
136
*
E04.2
ICD-10 Finland
Nontoxic multinodular goitre
3.7
137.8
651
1849
24220
ICD-8 Finland
Thyrotoxicosis with or without goitre, Thyrotoxicosis without mention of goitre
+∞
129.4
124
*
E03
ICD-10 Finland
Other hypothyroidism
2.9
125.9
861
3193
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.7
123.3
3566
24436
E89.09
ICD-10 Finland
Postprocedural hypothyroidism, other or several procedures
33.2
120.9
160
49
E06.1
ICD-10 Finland
Subacute thyroiditis
+∞
120.0
115
*
BA3AT
NOMESCO Finland
Cytology of thyroid with ultrasound quidance
6.1
113.4
324
546
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
3.8
113.1
513
1403
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.9
108.0
1916
11129
E05.4
ICD-10 Finland
Thyrotoxicosis factitia
107.6
107.2
117
11
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.6
106.0
4257
31519
CA1BG
NOMESCO Finland
Eye and orbita MRI examination with high intensity magnet
21.6
102.7
153
72
TFP20
NOMESCO Finland
Cardiodefibrillation
2.7
100.1
728
2790
E06.3
ICD-10 Finland
Autoimmune thyroiditis
17.4
99.1
159
93
E04.9
ICD-10 Finland
Nontoxic goitre, unspecified
4.3
95.5
376
904
E89.2
ICD-10 Finland
Postprocedural hypoparathyroidism
14.9
86.0
146
99
E05.5
ICD-10 Finland
Thyroid crisis or storm
+∞
84.5
81
*
E06.9
ICD-10 Finland
Thyroiditis, unspecified
36.0
82.7
107
30
H05.2
ICD-10 Finland
Exophthalmic conditions
21.9
81.8
121
56
207
Kela drug reimbursment
Chronic arrhythmias
1.9
81.4
1260
6893
C07AA07
ATC
sotalol; systemic
3.3
77.6
422
1330
2505
FHL
Bilateral resection (also used if total removal has been performed on the other side)
7.8
72.2
171
222
H02AB06
ATC
prednisolone; systemic
1.5
69.4
4381
34749
E03.80
ICD-10 Finland
Hypothyroidism caused by autoimmune thyroiditis
3.8
68.9
306
820
C07AB02
ATC
metoprolol; systemic
1.6
66.3
1865
12262
E89.0
ICD-10 Finland
Postprocedural hypothyroidism
26.9
63.4
88
33
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.4
61.2
3758
29404
B01AA03
ATC
warfarin; systemic
1.7
59.7
1563
10044
E06.2
ICD-10 Finland
Chronic thyroiditis with transient thyrotoxicosis
293.6
57.3
58
*
A11CC03
ATC
alfacalcidol; systemic
3.7
56.8
260
716
BAA25
NOMESCO Finland
Bilateral partial excision of thyroid gland
16.5
55.5
90
55
2422A
ICD-9 Finland
Thyrotoxicosis with or without goitre, Toxic multinodular goitre
+∞
55.2
53
*
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.7
53.7
1403
8986
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.7
52.0
1134
6890
C01AA05
ATC
digoxin; systemic
2.1
51.8
644
3207
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
7.3
51.3
126
174
E06.4
ICD-10 Finland
Drug-induced thyroiditis
500.4
50.4
50
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.5
49.1
1981
14081
TFP46
NOMESCO Finland
Ablation treatment of atrial fibrillation
4.4
49.0
186
433
C03CA01
ATC
furosemide; systemic
1.5
48.1
2282
16776
R00.0
ICD-10 Finland
Tachycardia, unspecified
2.4
47.6
412
1731
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
3.7
47.3
218
605
CAC30
NOMESCO Finland
Decompression of orbit to sinuses
241.1
47.0
48
*
I50.9
ICD-10 Finland
Heart failure, unspecified
1.7
47.0
1001
6028
TPH04
NOMESCO Finland
Cathetrisation of vein
1.5
46.8
1777
12442
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.7
45.9
981
5912
TFP34
NOMESCO Finland
Electrophysiological investigation
2.9
45.4
293
1039
R00.2
ICD-10 Finland
Palpitations
1.9
44.7
701
3813
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.5
44.4
1689
11819
H03BB02
ATC
thiamazole; oral
115.5
42.7
46
*
CA1AD
NOMESCO Finland
Orbita CT
15.6
42.5
70
45
WX408
NOMESCO Finland
General anesthesy, balanced
1.4
42.0
2327
17557
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.7
41.5
1043
6577
H04.10
ICD-10 Finland
Dry eye syndrome
1.7
40.6
935
5752
XF400
NOMESCO Finland
ECG with 12 standard connections
1.6
40.5
1310
8810
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
2.1
40.4
504
2509
E04.0
ICD-10 Finland
Nontoxic diffuse goitre
4.8
40.2
138
291
H53.2
ICD-10 Finland
Diplopia
2.6
39.2
292
1131
XF404
NOMESCO Finland
Ambulatory ECG
1.8
38.5
768
4524
TFC25
NOMESCO Finland
Transseptal catheterisation of left atrium or ventricle
4.4
38.4
144
333
N02BE01
ATC
paracetamol; systemic, rectal
1.4
38.1
8282
77088
106
Kela drug reimbursment
Hypoparathyroidism
8.0
37.9
87
109
A02BC02
ATC
pantoprazole; systemic
1.3
37.9
5961
52760
I47.2
ICD-10 Finland
Ventricular tachycardia
3.3
37.6
193
585
TFP35
NOMESCO Finland
Electroanatomical mapping
3.9
37.1
156
402
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.5
37.0
1397
9720
BAA40
NOMESCO Finland
Unilateral lobectomy of thyroid gland
2.7
36.5
260
980
R94.6
ICD-10 Finland
Abnormal results of thyroid function studies
7.0
36.2
91
131
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
2.0
36.2
476
2421
C01BC04
ATC
flecainide; systemic
2.4
35.6
312
1319
H50.2
ICD-10 Finland
Vertical strabismus
5.3
34.6
108
206
ZXA10
NOMESCO Finland
Bilateral
1.4
34.4
1607
11673
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.4
33.9
2416
18924
CAC44
NOMESCO Finland
Combined decompression of orbit
328.2
32.9
33
*
E83.51
ICD-10 Finland
Hypocalcemia
6.0
32.4
91
153
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
2.1
32.3
367
1757
R53
ICD-10 Finland
Malaise and fatigue
1.4
31.8
1772
13285
E05.3
ICD-10 Finland
Thyrotoxicosis from ectopic thyroid tissue
+∞
30.2
29
*
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
2.1
30.2
365
1794
ZX120
NOMESCO Finland
Intravenous
1.6
29.9
770
4870
B01AF02
ATC
apixaban; oral
1.7
29.9
725
4510
K78
ICPC
Atrial fibrillation/flutter
1.8
29.8
554
3188
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
1.9
29.7
444
2373
K80
ICPC
Cardiac arrhythmia NOS
1.7
29.3
628
3773
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
2.2
29.3
308
1426
C73.91
ICD-10 Finland
Papillary carcinoma of the thyroid gland (thyroid gland)
3.1
29.2
162
522
2423X
ICD-9 Finland
Thyrotoxicosis with or without goitre, Toxic nodular goitre, unspecified
+∞
29.2
28
*
K04
ICPC
Palpitations/awareness of heart
1.9
29.2
457
2481
R06.0
ICD-10 Finland
Dyspnoea
1.4
29.0
2047
15943
H04AA01
ATC
glucagon; nasal, parenteral
2.6
28.9
210
804
H02AB07
ATC
prednisone; oral
1.5
28.8
1227
8722
C03DA01
ATC
spironolactone; oral
1.6
28.2
811
5277
WX402
NOMESCO Finland
General anaesthesia
1.4
28.2
1367
9968
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
2.4
28.0
242
1019
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.4
27.6
1448
10709
E07.9
ICD-10 Finland
Disorder of thyroid, unspecified
10.2
27.3
54
53
E03.0
ICD-10 Finland
Congenital hypothyroidism with diffuse goitre
4.2
27.3
105
251
R07.4
ICD-10 Finland
Chest pain, unspecified
1.3
26.7
2139
16958
SPAT1249
SPAT
Treatment-related counselling outside office
1.3
26.4
3508
29798
A11CC02
ATC
dihydrotachysterol; oral
7.9
26.3
60
76
CBK00
NOMESCO Finland
Myotomy or resection of tarsal muscle or levator muscle of eyelid for correction of retraction
135.3
25.6
27
*
XCW99
NOMESCO Finland
Other investigative procedure of eye
1.5
25.6
881
5979
T89
ICPC
Diabetes insulin dependent
2.1
25.2
307
1513
R03AC02
ATC
salbutamol; inhalant
1.2
24.5
4681
41374
BAA50
NOMESCO Finland
Lobectomy and resection of contralateral lobe of thyroid gland
9.8
24.4
49
50
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
1.9
23.8
364
1961
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
1.7
23.8
546
3345
CAC20
NOMESCO Finland
Lateral decompression of orbit
125.3
23.6
25
*
XCK10
NOMESCO Finland
Photography of fundus of eye
1.5
23.2
759
5088
H02AB09
ATC
hydrocortisone; systemic
2.4
23.2
201
850
XCK00
NOMESCO Finland
Perimetry
1.7
22.8
540
3335
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
2.4
22.8
192
800
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.4
22.7
1008
7205
H50.6
ICD-10 Finland
Mechanical strabismus
25.9
22.6
31
12
C09AA05
ATC
ramipril; oral
1.3
22.5
1720
13491
I42.0
ICD-10 Finland
Dilated cardiomyopathy
2.5
22.4
184
756
E04.1
ICD-10 Finland
Nontoxic single thyroid nodule
2.5
22.1
175
705
E06.0
ICD-10 Finland
Acute thyroiditis
23.9
22.1
31
13
XCD10
NOMESCO Finland
Electrophysiological examination of eye
2.2
22.0
218
982
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
2.0
21.9
287
1461
A10AE04
ATC
insulin glargine; parenteral
1.6
21.9
653
4278
G73.0*E05.9
ICD-10 Finland
Myasthenic syndromes in thyrotoxicosis [hyperthyroidism]
+∞
21.9
21
*
E05.8
ICD-10 Finland
Other thyrotoxicosis
+∞
21.9
21
*
M14.5*E05.9
ICD-10 Finland
Arthropathy in thyrotoxicosis [hyperthyroidism]
220.4
21.6
22
*
8260/3-C73.9
ICD-O-3
Papillary adenocarcinoma, NOS, of thyroid gland
2.8
21.5
137
487
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.3
21.5
2567
21381
201
Kela drug reimbursment
Chronic cardiac insufficiency
1.9
21.4
314
1665
SPAT1262
SPAT
Handing over of treatment supplies
1.4
21.3
1341
10196
I42.9
ICD-10 Finland
Cardiomyopathy, unspecified
3.0
21.1
124
419
E05.81
ICD-10 Finland
Overproduction of thyroid-stimulating hormone
+∞
20.8
20
*
J01DB01
ATC
cefalexin; oral
1.3
20.8
7587
71325
A10AB04
ATC
insulin lispro; parenteral (insulins and analog. for injection, fast-acting)
2.0
20.6
261
1308
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.2
20.6
3051
26040
I50.1
ICD-10 Finland
Left ventricular failure
2.0
20.6
285
1481
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
1.6
20.6
555
3549
A04
ICPC
Weakness/tiredness general
1.4
20.5
1043
7641
Z01.8
ICD-10 Finland
Other specified special examinations
1.3
20.4
1728
13739
A10AA01
ATC
NA
2.1
20.4
221
1041
A10AE05
ATC
insulin detemir; parenteral
1.7
20.4
399
2331
WX892
NOMESCO Finland
Monitored bed care
1.6
20.3
532
3375
O90.5
ICD-10 Finland
Postpartum thyroiditis
22.4
20.3
29
13
I10
ICD-10 Finland
Essential (primary) hypertension
1.2
20.2
4580
40893
E89.9
ICD-10 Finland
Postprocedural endocrine and metabolic disorder, unspecified
32.6
20.1
26
8
J01AA02
ATC
doxycycline; systemic
1.2
20.1
7216
67539
XW1AT
NOMESCO Finland
Biopsy from other organ close to skin with ultrasound quidance
4.1
20.0
79
196
WX110
NOMESCO Finland
Local anesthesy
1.2
19.9
6127
56389
2421A
ICD-9 Finland
Thyrotoxicosis with or without goitre, Toxic uninodular goitre
+∞
19.8
19
*
BA1AN
NOMESCO Finland
Thyroid gland isotope imaging
+∞
19.8
19
*
I50.0
ICD-10 Finland
Congestive heart failure
1.7
19.1
440
2698
B01AB05
ATC
enoxaparin; parenteral
1.3
18.9
2490
20927
T81
ICPC
Goitre
4.9
18.9
61
124
J01DA01
ATC
[U] cefalexin; systemic
1.2
18.9
5651
51718
24199
ICD-8 Finland
Non-toxic nodular goitre, Unspecified
3.1
18.6
103
335
342
Kela drug reimbursment
Dronedarone
3.8
18.6
80
214
A10AA02
ATC
NA
1.9
18.5
260
1362
AA1AD
NOMESCO Finland
CT of head and brain
1.3
18.5
1755
14155
TFP47
NOMESCO Finland
Ablation or modification of the AV-node
4.7
18.4
62
132
BBA70
NOMESCO Finland
Implantation or transplantation of parathyroid gland
12.8
18.3
32
25
H3600, E103
ICD-10 Finland
NA
3.0
18.3
108
368
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.3
18.2
1335
10385
I48.1
ICD-10 Finland
Persistent atrial fibrillation
2.2
18.2
184
842
H50.8
ICD-10 Finland
Other specified strabismus
10.3
18.1
35
34
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.3
18.1
1696
13655
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
2.3
18.0
170
754
SPAT1263
SPAT
Sampling
1.2
18.0
3636
31968
XF600
NOMESCO Finland
Bloodpressure measurement
1.6
17.9
452
2842
J01CA04
ATC
amoxicillin; systemic
1.2
17.7
7468
70454
AR6
HP
Catheter ablation of arrhythmia, target: atrial fibrillation
5.0
17.6
56
112
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.3
17.5
1355
10615
I47.1
ICD-10 Finland
Supraventricular tachycardia
1.8
17.5
319
1827
R03BB04
ATC
tiotropium bromide; inhalant
1.5
17.2
639
4401
K90.0
ICD-10 Finland
Coeliac disease
1.9
17.2
241
1264
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.3
17.1
1922
15824
B03BA03
ATC
hydroxocobalamin; parenteral
1.6
16.9
400
2474
J45.9
ICD-10 Finland
Asthma, unspecified
1.3
16.9
1402
11091
FPG30
NOMESCO Finland
Implantation of cardioverter-defibrillator with ventricular electrode
4.8
16.7
55
115
E10
ICD-10 Finland
Type 1 diabetes mellitus
2.4
16.5
145
619
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
1.5
16.4
560
3784
I49.3
ICD-10 Finland
Ventricular premature depolarization
1.5
16.4
500
3294
Z71.8
ICD-10 Finland
Other specified counselling
1.3
16.4
1916
15834
N02AX02
ATC
tramadol; systemic, rectal
1.2
16.3
3400
29892
C01BD07
ATC
dronedarone; oral
3.9
16.3
66
169
GB1AA
NOMESCO Finland
Tracheal X-ray examination
12.1
16.3
29
24
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.2
16.3
4730
42897
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.4
16.2
1013
7677
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
1.5
16.2
533
3575
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.3
16.0
1157
8966
24400
ICD-8 Finland
Myxoedema, (hypothyreosis) post therapiam
13.5
15.9
27
20
R50.9
ICD-10 Finland
Fever, unspecified
1.4
15.8
998
7576
Z01.7
ICD-10 Finland
Laboratory examination
1.4
15.8
856
6338
XF402
NOMESCO Finland
ECG with work load test
1.4
15.7
768
5581
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.2
15.7
2002
16712
A02BC01
ATC
omeprazole; systemic
1.2
15.4
2247
19035
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.4
15.3
923
6952
FPG32
NOMESCO Finland
Implantation of cardioverter-defibrillator with atrial and ventricular electrodes
3.8
15.3
64
169
A02BC05
ATC
esomeprazole; systemic
1.2
15.3
3436
30381
2429X
ICD-9 Finland
Thyrotoxicosis with or without goitre, Thyrotoxicosis without mention of goitre or other cause
13.9
15.0
25
18
FJA10
NOMESCO Finland
Transvenous biopsy of right ventricle
4.5
14.9
52
116
E34.9
ICD-10 Finland
Endocrine disorder, unspecified
4.2
14.8
56
135
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
2.5
14.7
112
446
R11
ICD-10 Finland
Nausea and vomiting
1.4
14.7
619
4372
SPAT1097
SPAT
Recording of ECG
1.3
14.6
1086
8445
103
Kela drug reimbursment
Diabetes, insulin-treated
1.2
14.6
1820
15135
R63.4
ICD-10 Finland
Abnormal weight loss
1.8
14.4
238
1322
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.2
14.4
3815
34186
J01FA10
ATC
azithromycin; systemic
1.2
14.3
5177
47619
AQ2
HP
Electrophysiological electroanatomical examination
4.2
14.3
53
126
107
Kela drug reimbursment
Pernicious anaemia
2.2
14.2
147
683
O24.0
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, insulin-dependent
2.3
14.2
130
570
AQ1
HP
Conventional electrophysiological examination
2.7
14.2
94
347
N05BA04
ATC
oxazepam; oral
1.2
14.1
2069
17512
E21.09
ICD-10 Finland
Other primary hyperparathyroidism
2.1
14.0
155
742
L28
ICPC
Limited function/disability (L)
1.3
14.0
1141
8990
E20.8
ICD-10 Finland
Other hypoparathyroidism
10.9
14.0
26
24
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.2
13.9
4297
38971
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.3
13.9
956
7348
CEC00
NOMESCO Finland
Recession of extraocular muscle
4.2
13.8
51
121
E50.0
ICD-10 Finland
Vitamin A deficiency with conjunctival xerosis
53.4
13.8
16
*
CEC90
NOMESCO Finland
Total transposition of extraocular muscle or muscles
53.4
13.8
16
*
E89.1
ICD-10 Finland
Postprocedural hypoinsulinaemia
20.0
13.7
20
10
R60.0
ICD-10 Finland
Localized oedema
1.4
13.6
785
5870
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.3
13.5
1267
10167
2441A
ICD-9 Finland
Acquired hypothyroidism, Other postablative hypothyroidism
34.0
13.5
17
5
R13
ICD-10 Finland
Dysphagia
1.5
13.4
444
2986
TFP44
NOMESCO Finland
Ablation treatment of typical atrial flutter
3.4
13.3
64
191
R02
ICPC
Shortness of breath/dyspnoea
1.3
13.1
876
6707
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.3
13.1
1528
12599
R4110
NOMESCO Finland
Physiotherapy
1.2
13.1
2043
17389
N05CF01
ATC
zopiclone; oral
1.2
13.0
2603
22692
177
Kela drug reimbursment
Insulin glargine 300 U / ml
2.1
12.8
141
673
WX002
NOMESCO Finland
Sedation and analgesia
1.3
12.8
1492
12294
CA1BD
NOMESCO Finland
Extensive orbita CT
11.5
12.8
23
20
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.2
12.5
2642
23122
I49.8
ICD-10 Finland
Other specified cardiac arrhythmias
1.8
12.5
206
1147
CA1BM
NOMESCO Finland
Eye and orbita MRI examination with 3 Tesla magnet
17.3
12.5
19
11
GD1LA
NOMESCO Finland
GD
2.5
12.5
97
392
I49.5
ICD-10 Finland
Sick sinus syndrome
1.7
12.3
243
1432
A10AE06
ATC
insulin degludec; parenteral
1.8
12.3
196
1080
A29
ICPC
General symptom/complaint other
1.3
12.3
786
5976
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.4
12.2
545
3895
E07.89
ICD-10 Finland
Other specified disorders of thyroid
8.9
12.2
25
28
C08CA01
ATC
amlodipine; oral
1.2
12.2
2566
22450
B81
ICPC
Anaemia vit B12/folate deficiency
1.7
12.1
251
1498
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.2
12.1
2303
19956
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.4
12.0
524
3726
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.3
12.0
1072
8542
289
Kela drug reimbursment
Combination product containing sacubitril and valsartan
3.3
12.0
59
180
K02.1
ICD-10 Finland
Caries of dentine
1.2
12.0
4762
43868
2AB04
NOMESCO Finland
NA
5.3
11.9
35
66
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
1.6
11.9
327
2107
Z01.9
ICD-10 Finland
Special examination, unspecified
1.5
11.9
397
2676
AN1
HP
Coronary angiography
1.4
11.9
690
5167
R51.80
ICD-10 Finland
Headache
1.3
11.8
1138
9154
H3601, E103
ICD-10 Finland
NA
2.7
11.8
79
295
ARB
HP
Catheter ablation of arrhythmia: Cutiing or modification of the AV node
11.7
11.8
21
18
A12AA04
ATC
calcium carbonate; oral
2.3
11.7
107
472
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.2
11.6
1814
15414
E83.50
ICD-10 Finland
Hypercalcemia
2.3
11.6
101
435
N02AJ06
ATC
codeine and paracetamol; systemic
1.2
11.6
2945
26168
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.3
11.6
1248
10183
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
1.4
11.5
588
4308
C09DX04
ATC
valsartan and sacubitril; oral
3.4
11.4
54
160
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.2
11.4
2298
20002
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
1.4
11.4
605
4463
SPAT1301
SPAT
No procedures
1.2
11.3
2513
22062
8341/3-C73.9
ICD-O-3
Papillary microcarcinoma of thyroid gland
9.6
11.2
22
23
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.2
11.2
4026
36739
R01AD08
ATC
fluticasone; nasal
1.2
11.1
2326
20303
UDQ12
NOMESCO Finland
Flexible laryngoscopy
1.5
11.1
385
2619
R42
ICD-10 Finland
Dizziness and giddiness
1.2
11.1
1662
14062
UJF32
NOMESCO Finland
Coloscopy
1.2
11.1
1936
16628
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.3
11.0
1222
10000
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.2
10.9
1814
15505
1CX08
NOMESCO Finland
NA
4.4
10.8
38
87
R21
ICPC
Throat symptom/complaint
1.2
10.8
1514
12716
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.2
10.8
1275
10512
7AX01
NOMESCO Finland
NA
17.8
10.7
16
9
A12BA01
ATC
potassium chloride; oral
1.6
10.7
300
1943
BAA20
NOMESCO Finland
Unilateral partial excision of thyroid gland
3.8
10.7
44
117
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.2
10.7
1432
11966
K29.4
ICD-10 Finland
Chronic atrophic gastritis
1.9
10.7
153
814
FM1DG
NOMESCO Finland
Very extensive MRI examination of heart with high intesity magnet
2.4
10.6
86
358
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.2
10.6
3593
32592
CEC10
NOMESCO Finland
Recession and resection of extraocular muscle
3.1
10.6
56
181
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.2
10.6
3273
29491
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
1.5
10.5
402
2791
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
1.4
10.5
497
3593
H36.00
ICD-10 Finland
Diabetic background retinopathy
2.3
10.5
97
433
I50
ICD-10 Finland
Heart failure
1.8
10.5
188
1081
N03AX12
ATC
gabapentin; oral
1.3
10.4
1147
9378
24599
ICD-8 Finland
Thyroiditis, Unspecified
+∞
10.4
10
*
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.3
10.4
767
5957
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
2.7
10.3
70
265
2440A
ICD-9 Finland
Acquired hypothyroidism, Postsurgical hypothyroidism
12.0
10.3
18
15
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.2
10.3
1443
12112
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.2
10.3
1801
15453
H57.1
ICD-10 Finland
Ocular pain
1.6
10.2
228
1396
SPAT1255
SPAT
Intravenous administration of medicine
1.4
10.2
437
3105
A60
ICPC
General and Unspecified, Result test/procedure
1.5
10.1
306
2020
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.2
10.1
1538
13020
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
1.8
10.1
164
914
AR5
HP
Catheter ablation of arrhythmia, target: atrial flutter
4.7
10.1
33
71
M03BX02
ATC
tizanidine; oral
1.1
10.0
5425
50815
D44.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Thyroid gland
2.1
10.0
113
549
J01FA06
ATC
roxithromycin; oral
1.2
10.0
3388
30703
H02.5
ICD-10 Finland
Other disorders affecting eyelid function
4.9
10.0
31
63
TPH07
NOMESCO Finland
Cathetrisation of artery
1.3
10.0
657
5016
381
Kela drug reimbursment
Combination product containing sacubitril and valsartan
3.3
10.0
49
151
J01FF01
ATC
clindamycin; systemic
1.2
10.0
2090
18228
R03BA02
ATC
budesonide; inhalant
1.2
9.9
1356
11350
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
1.4
9.9
499
3650
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
1.3
9.9
592
4455
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
2.6
9.9
67
254
E04.8
ICD-10 Finland
Other specified nontoxic goitre
3.6
9.8
43
121
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.2
9.8
1996
17360
C08DA01
ATC
verapamil; systemic
1.6
9.8
276
1793
CA1CM
NOMESCO Finland
Eye and orbita extensive MRI examination with 3 Tesla magnet
4.6
9.8
32
69
FPG40
NOMESCO Finland
Replacement of pulse generator in transvenous cardioverter-defibrillator
7.0
9.8
23
33
C08DB01
ATC
diltiazem; oral
1.5
9.7
333
2263
SAA01
NOMESCO Finland
Simple examination of mouth
1.1
9.7
6163
58310
I49.0
ICD-10 Finland
Ventricular fibrillation and flutter
2.7
9.6
62
229
I47.9
ICD-10 Finland
Paroxysmal tachycardia, unspecified
2.0
9.6
119
600
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
1.7
9.6
176
1019
BA1AE
SPAT
NA
2.7
9.6
63
236
SGA01
NOMESCO Finland
Tooth opening as first aid
1.2
9.6
1132
9331
N02AA05
ATC
oxycodone; systemic
1.3
9.5
950
7672
FPH10
NOMESCO Finland
Open removal of transvenous cardiac pacemaker or cardioverter-defibrillator
6.3
9.5
24
38
C07AB03
ATC
atenolol; systemic
1.4
9.4
384
2701
2504
FHL
Unilateral resection or enucleation
2.5
9.4
69
274
R49.08
ICD-10 Finland
Other specified dysphonia
1.8
9.4
162
920
E89
ICD-10 Finland
Postprocedural endocrine and metabolic disorders, not elsewhere classified
100.1
9.4
10
*
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.3
9.4
890
7143
J01FA09
ATC
clarithromycin; systemic
1.2
9.4
2585
23042
N03AX16
ATC
pregabalin; oral
1.2
9.3
1801
15582
BEF00
NOMESCO Finland
Continuous subcutaneous glucose monitoring
2.9
9.3
54
186
R05
ICPC
Cough
1.2
9.3
1717
14793
WF099
NOMESCO Finland
Other radiotherapy
3.1
9.3
49
160
CEW99
NOMESCO Finland
Other operation on extraocular muscle
6.4
9.2
23
36
A98
ICPC
Health maint/preventive medicine
1.3
9.2
9384
91959
ZXA05
NOMESCO Finland
Left side
1.2
9.2
1896
16502
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.3
9.2
614
4702
H50.0
ICD-10 Finland
Convergent concomitant strabismus
2.9
9.2
54
189
E21.3
ICD-10 Finland
Hyperparathyroidism, unspecified
2.2
9.1
87
393
D01
ICPC
Abdominal pain/cramps general
1.3
9.1
768
6074
R06AE07
ATC
cetirizine; oral
1.1
9.1
3772
34608
ZXA00
NOMESCO Finland
Right side
1.2
9.1
2021
17697
WZC30
NOMESCO Finland
Teaching
1.3
9.1
908
7338
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.2
9.0
1062
8746
M14.5*E03.9
ICD-10 Finland
Arthropathy in hypothyroidism (E00-E03+)
4.4
9.0
31
71
H02AB04
ATC
methylprednisolone; systemic
1.2
9.0
1098
9081
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.2
8.9
1344
11357
A08
ICPC
Swelling
1.5
8.9
283
1893
CEC60
NOMESCO Finland
Transposition of extraocular muscle with adjustable suture
7.4
8.9
20
27
-60
ICPC
Result test/procedure
1.4
8.9
425
3085
G47.3
ICD-10 Finland
Sleep apnoea
1.2
8.9
1338
11305
I42.2
ICD-10 Finland
Other hypertrophic cardiomyopathy
2.8
8.9
54
194
N07BA03
ATC
varenicline; oral
1.5
8.8
327
2264
B01AF01
ATC
rivaroxaban; oral
1.3
8.8
763
6061
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
2.2
8.8
87
401
R00.1
ICD-10 Finland
Bradycardia, unspecified
1.7
8.7
185
1119
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.2
8.7
1063
8790
F29
ICPC
Eye symptom/complaint other
1.3
8.6
563
4297
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.3
8.6
875
7084
D64.9
ICD-10 Finland
Anaemia, unspecified
1.3
8.6
610
4709
TFP30
NOMESCO Finland
Cathetric examination for cardiac arrythmia
2.3
8.6
73
315
M79.6
ICD-10 Finland
Pain in limb
1.1
8.6
2883
26043
J01MA12
ATC
levofloxacin; systemic
1.2
8.6
1257
10593
R01AD09
ATC
mometasone; nasal
1.1
8.6
3821
35188
M03BC51
ATC
orphenadrine, combinations; systemic
1.2
8.4
2277
20235
W84
ICPC
Pregnancy high risk
1.6
8.4
196
1215
G04BE03
ATC
sildenafil; oral
2.5
8.4
65
265
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
1.3
8.4
492
3692
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
1.5
8.4
239
1560
AS7
HP
Arrhythmia pacemaker insertion VVI (R) S
5.6
8.4
23
41
A02BA02
ATC
ranitidine; systemic
1.2
8.4
1453
12437
L15
ICPC
Knee symptom/complaint
1.2
8.4
1572
13556
24509
ICD-8 Finland
Thyroiditis, Unspecified
+∞
8.3
8
*
O992, E050
ICD-10 Finland
NA
+∞
8.3
8
*
R07.3
ICD-10 Finland
Other chest pain
1.3
8.3
624
4860
R25.1
ICD-10 Finland
Tremor, unspecified
1.6
8.3
180
1099
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
2.3
8.3
73
320
SPAT1254
SPAT
Administration of medicine
1.2
8.3
1009
8343
J01CE02
ATC
phenoxymethylpenicillin; oral
1.1
8.2
5973
56664
4273A
ICD-9 Finland
Cardiac dysrhythmias, Atrial fibrillation and flutter
2.0
8.2
95
468
K05
ICPC
Irregular heartbeat other
1.6
8.2
192
1195
M54.5
ICD-10 Finland
Low back pain
1.1
8.2
2627
23640
-50
ICPC
Medication/prescr/renewal
1.5
8.2
284
1938
FPG96
NOMESCO Finland
Other implantation of permanent cardioverter-defibrillator
4.2
8.2
29
69
SPAT1312
SPAT
General health counselling
1.2
8.1
2530
22709
205
Kela drug reimbursment
Chronic hypertension
1.2
8.1
1857
16281
M81.0
ICD-10 Finland
Postmenopausal osteoporosis
1.6
8.1
183
1127
FPE96
NOMESCO Finland
Other implantation or replacement of transvenous cardiac pacemaker
3.5
8.1
36
104
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
1.5
8.1
295
2036
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.3
8.1
648
5095
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.1
8.0
3274
29935
G44.2
ICD-10 Finland
Tension-type headache
1.2
8.0
1028
8541
A99
ICPC
Disease/condition unspecnature/site
1.3
8.0
540
4141
M01AE03
ATC
ketoprofen; systemic, rectal
1.1
8.0
2966
26943
FM1CD
NOMESCO Finland
Very extensive CT of heart
4.0
8.0
30
75
BWD00
NOMESCO Finland
Reoperation for deep haemorrhage in endocrine surgery
8.9
8.0
16
18
E06
ICD-10 Finland
Thyroiditis
10.0
8.0
15
15
TFP52
NOMESCO Finland
Ablation treatment of ventricular tachycardia due to structural heart defect
10.0
8.0
15
15
A09
ICPC
Sweating problem
2.2
8.0
79
366
C09CA01
ATC
losartan; oral
1.2
7.9
1679
14625
R60.9
ICD-10 Finland
Oedema, unspecified
1.4
7.9
311
2178
A27
ICPC
Fear of other disease NOS
1.5
7.9
285
1965
E06.5
ICD-10 Finland
Other chronic thyroiditis
13.0
7.9
13
10
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.2
7.9
1282
10913
CE2W4
NOMESCO Finland
Eye movement mapping
5.1
7.8
23
45
A91
ICPC
Abnormal result investigation NOS
1.5
7.8
268
1826
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
1.3
7.8
561
4344
I34.00
ICD-10 Finland
Mitral (valve) incompetence NOS or of specified cause, except rheumatic
1.8
7.8
117
638
A10AB06
ATC
insulin glulisine; parenteral
2.3
7.8
65
280
UDH02
NOMESCO Finland
Rhinopharyngoscopy
1.4
7.7
418
3100
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.1
7.7
2464
22153
B01AB04
ATC
dalteparin; parenteral
1.4
7.7
317
2243
L17
ICPC
Foot/toe symptom/complaint
1.2
7.7
1891
16670
WX290
NOMESCO Finland
Other blockade of nerve
1.1
7.7
3494
32155
M25.5
ICD-10 Finland
Pain in joint
1.2
7.6
2284
20434
TKC20
NOMESCO Finland
Catheterisation of bladder
1.4
7.6
409
3030
FPE00
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with ventricular electrode
1.8
7.6
116
638
J02AC01
ATC
fluconazole; systemic
1.1
7.6
3738
34563
SPAT1260
SPAT
Consultation of another employee
1.2
7.6
1324
11337
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
1.3
7.6
542
4197
D06
ICPC
Abdominal pain localized other
1.3
7.5
562
4374
R01AD12
ATC
fluticasone furoate; nasal
1.1
7.5
2364
21219
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
2.0
7.5
84
412
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
1.3
7.5
545
4228
L03
ICPC
Low back symptom/complaint
1.2
7.5
1868
16485
C09AA02
ATC
enalapril; systemic
1.2
7.5
1289
11030
WX320
NOMESCO Finland
Spinalanesthesy
1.2
7.5
1692
14820
WX902
NOMESCO Finland
External defibrillation of heart
3.8
7.4
29
76
BA1MN
NOMESCO Finland
Thyroid gland isotope imaging with calculation
80.1
7.4
8
*
C03AA03
ATC
hydrochlorothiazide; oral
1.3
7.4
654
5208
R07.0
ICD-10 Finland
Pain in throat
1.4
7.4
412
3071
I11.0
ICD-10 Finland
Hypertensive heart disease with (congestive) heart failure
1.7
7.4
134
777
E20.9
ICD-10 Finland
Hypoparathyroidism, unspecified
5.3
7.4
21
40
MAA00
NOMESCO Finland
Amniocentesis
1.7
7.4
148
884
GD6BD
NOMESCO Finland
Extensive CT of chest and neck
4.5
7.4
24
53
A02BC03
ATC
lansoprazole; oral
1.1
7.3
2270
20348
E04
ICD-10 Finland
Other nontoxic goitre
3.3
7.3
34
103
SPAT1216
SPAT
Assessment of functional ability
1.2
7.3
1042
8756
2451A
ICD-9 Finland
Thyroiditis, Subacute thyroiditis
+∞
7.3
7
*
3762A
ICD-9 Finland
Disorders of the orbit, Endocrine exophthalmos
+∞
7.3
7
*
E50.9
ICD-10 Finland
Vitamin A deficiency, unspecified
10.8
7.3
13
12
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
1.6
7.3
164
1012
-34
ICPC
Blood test
1.6
7.3
198
1285
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.1
7.2
4375
40919
UGC12
NOMESCO Finland
Flexible bronchoscopy
1.3
7.2
425
3198
SPAT1283
SPAT
Restricted health certificate
1.2
7.2
1289
11059
I34.09
ICD-10 Finland
Mitral (valve) insufficiency
1.5
7.2
237
1604
I48.2
ICD-10 Finland
Chronic atrial fibrillation
1.7
7.2
138
815
E27.1
ICD-10 Finland
Primary adrenocortical insufficiency
3.3
7.2
33
99
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
1.6
7.2
170
1065
J03.9
ICD-10 Finland
Acute tonsillitis, unspecified
1.4
7.2
304
2161
FPJ21
NOMESCO Finland
Revision of cardioverter-defibrillator with ventricular electrode
7.3
7.2
16
22
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.1
7.2
4763
44785
N06AX11
ATC
mirtazapine; oral
1.1
7.1
2517
22761
T90
ICPC
Diabetes non-insulin dependent
1.2
7.1
1464
12715
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.2
7.1
1501
13069
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
1.3
7.1
586
4630
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.2
7.1
962
8046
R03BA05
ATC
fluticasone; inhalant
1.2
7.1
1371
11850
M79.0
ICD-10 Finland
Rheumatism, unspecified
1.4
7.0
267
1862
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
2.6
7.0
49
190
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
1.5
7.0
203
1336
A12AA06
ATC
calcium lactate gluconate; oral
4.7
7.0
22
47
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.2
7.0
974
8165
UKC02
NOMESCO Finland
Cystoscopy
1.2
6.9
917
7646
ZX108
NOMESCO Finland
Inhalation
2.5
6.9
49
193
A03
ICPC
Fever
1.2
6.9
1096
9305
XF602
NOMESCO Finland
Bloodpressure monitoring
2.1
6.9
69
323
FQA10
NOMESCO Finland
Orthotopic transplantation of heart with bicaval anastomosis
7.5
6.9
15
20
ZYC06
NOMESCO Finland
Real-time text-based remote transaction
4.6
6.9
22
48
FPE20
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with atrial and ventricular electrodes
1.5
6.9
221
1490
R03AK03
ATC
[D] fenoterol & other drugs for obstructive airway dis; inhalant
1.4
6.9
297
2122
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.2
6.9
1265
10885
UJF30
NOMESCO Finland
Ileoscopy through colon
1.3
6.8
643
5161
FPE30
NOMESCO Finland
Replacement of transvenous cardiac pacemaker pulse generator
2.0
6.8
76
373
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.3
6.8
612
4884
Z32.1
ICD-10 Finland
Pregnancy confirmed
1.3
6.8
581
4606
42792
ICD-8 Finland
Symptomatic heart disease, Fibrillatio auricularis
2.7
6.8
44
164
O24.4
ICD-10 Finland
Diabetes mellitus arising in pregnancy
1.3
6.8
514
4014
TFP45
NOMESCO Finland
Ablation treatment of non-typical atrial flutter
6.1
6.8
17
28
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
1.4
6.7
301
2166
L14
ICPC
Leg/thigh symptom/complaint
1.3
6.7
479
3705
P01AB01
ATC
metronidazole; oral, rectal
1.1
6.6
3358
31032
I41.8*D86.8
ICD-10 Finland
Sarcoid myocarditis
3.7
6.6
27
74
N17
ICPC
Vertigo/dizziness
1.2
6.6
761
6252
R52.9
ICD-10 Finland
Pain, unspecified
1.3
6.6
575
4572
A28
ICPC
Limited function/disability NOS
1.2
6.6
935
7850
N05CF02
ATC
zolpidem; oral
1.2
6.6
1344
11657
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
1.3
6.6
385
2895
PH1AC
NOMESCO Finland
Flebography of over extremity with X-ray
2.0
6.6
76
378
105
Kela drug reimbursment
Adrenal cortical hypofunction
3.5
6.6
28
80
Z02.7
ICD-10 Finland
Issue of medical certificate
1.4
6.6
367
2740
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
1.5
6.6
193
1276
K77
ICPC
Heart failure
1.8
6.5
107
605
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
1.4
6.5
287
2058
E21.2
ICD-10 Finland
Other hyperparathyroidism
2.9
6.5
36
124
RD210
NOMESCO Finland
NA
1.8
6.5
112
641
H3603, E103
ICD-10 Finland
NA
2.2
6.5
64
298
S06.0
ICD-10 Finland
Concussion
1.2
6.5
675
5483
C10AA05
ATC
atorvastatin; oral
1.1
6.5
2581
23504
M79.1
ICD-10 Finland
Myalgia
1.2
6.5
921
7734
SGA02
NOMESCO Finland
Opening and dilatation of root canal of tooth
1.2
6.5
840
6992
J45.1
ICD-10 Finland
Nonallergic asthma
1.3
6.5
455
3518
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
1.2
6.5
931
7833
AS8
HP
Physiological arrhythmia pacemaker insertionDDD (R) S
5.3
6.4
18
34
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
1.3
6.4
504
3954
SPAT1229
SPAT
Assessment of need for aid
1.3
6.4
514
4044
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
1.3
6.4
565
4500
A50
ICPC
General and Unspecified, Medication/prescr/renewal
1.5
6.4
205
1378
6481A
ICD-9 Finland
Other current conditions in the mother classifiable elsewhere but complicating pregnancy, childbirth and the puerperium, Thyroid dysfunction[HYPERTHYREOSIS IN GRAVIDITATE]
14.3
6.4
10
7
XF640
NOMESCO Finland
NA
1.6
6.4
166
1066
M75.0
ICD-10 Finland
Adhesive capsulitis of shoulder
1.3
6.4
363
2723
N30.0
ICD-10 Finland
Acute cystitis
1.2
6.4
1089
9309
TCC40
NOMESCO Finland
Closure of lacrimal canaliculus with plug
3.1
6.3
31
99
3AC01
NOMESCO Finland
NA
2.0
6.3
70
345
SPAT1310
SPAT
Counselling related to known health issue
1.1
6.3
2472
22484
I48.4
ICD-10 Finland
Atypical atrial flutter
3.4
6.3
28
83
TBA20
NOMESCO Finland
Aspiration cytology of thyroid gland
5.5
6.3
17
31
M01AB55
ATC
diclofenac, combinations; oral
1.3
6.3
476
3721
C08CA02
ATC
felodipine; oral
1.3
6.3
568
4540
J01MA02
ATC
ciprofloxacin; systemic
1.1
6.3
2908
26720
A13
ICPC
Concern/fear medical treatment
1.8
6.3
106
606
CKC12
NOMESCO Finland
Photocoagulation of retina
1.4
6.3
251
1772
TK810
NOMESCO Finland
Hemofiltration
2.9
6.3
36
125
2452A
ICD-9 Finland
Thyroiditis, Chronic lymphocytic thyroiditis
+∞
6.2
6
*
E8901, E050
ICD-10 Finland
NA
+∞
6.2
6
*
I43.8*E05.9
ICD-10 Finland
Thyrotoxic heart disease
+∞
6.2
6
*
R05FB02
ATC
cough suppressants and expectorants
1.1
6.2
3041
28021
I25.2
ICD-10 Finland
Old myocardial infarction
1.4
6.2
304
2225
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
1.4
6.2
268
1921
Z01.2
ICD-10 Finland
Dental examination
1.1
6.2
3289
30463
WZA90
NOMESCO Finland
Other doctors statement
1.2
6.2
1682
14927
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
1.4
6.1
273
1962
WX872
NOMESCO Finland
Intensive care
1.4
6.1
255
1812
R05FA02
ATC
opium derivatives and expectorants; systemic
1.1
6.1
3310
30669
L95
ICPC
Osteoporosis
1.5
6.1
215
1479
O99.5
ICD-10 Finland
Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium
2.3
6.1
53
232
J44
ICD-10 Finland
Other chronic obstructive pulmonary disease
1.7
6.1
112
655
PA6CG
NOMESCO Finland
Extensive MRI examination of neck vasculature with high intensity magnet
3.1
6.1
30
96
M02AA07
ATC
piroxicam; topical
1.1
6.1
2925
26917
L12
ICPC
Hand/finger symptom/complaint
1.2
6.1
979
8320
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.1
6.1
3136
28977
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
1.4
6.1
278
2011
D09
ICPC
Nausea
1.4
6.1
268
1923
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.2
6.1
839
7025
3A149
NOMESCO Finland
NA
12.5
6.1
10
8
I49.1
ICD-10 Finland
Atrial premature depolarization
1.5
6.1
211
1446
P06
ICPC
Sleep disturbance
1.2
6.0
639
5201
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
1.4
6.0
251
1786
M04AA01
ATC
allopurinol; systemic
1.2
6.0
665
5439
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
1.4
6.0
300
2200
Mortality – FinRegistry
↥Association
Association between endpoint THYROTOXICOSIS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| THYROTOXICOSIS | 1.218 [1.12, 1.33] | < 0.001 |
| Birth year | 0.993 [0.99, 1.0] | 0.103 |
During the follow-up period (1.1.1998 — 31.12.2019), 6988 out of 42750 females with THYROTOXICOSIS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| THYROTOXICOSIS | 1.423 [1.28, 1.58] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.017 |
During the follow-up period (1.1.1998 — 31.12.2019), 2308 out of 10455 males with THYROTOXICOSIS died.
Mortality risk
Mortality risk for people of age
years, who have THYROTOXICOSIS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.107% | 0.312% |
| 5 | 0.702% | 1.743% |
| 10 | 1.649% | 4.371% |
| 15 | 3.151% | 8.243% |
| 20 | 5.552% | 13.497% |
Relationships between endpoints
↥Index endpoint: THYROTOXICOSIS – Thyrotoxicosis
GWS hits: 37
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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