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Thyrotoxicosis, other and/or unspecified

E4_THYTOXNAS

Thyrotoxicosis: A hypermetabolic syndrome caused by the elevation of thyroid hormone levels in the serum. Signs and symptoms include tachycardia, palpitations, tremor, weight loss, warm weather intolerance, and moist skin. Causes include Graves disease, toxic nodular goiter, toxic thyroid nodule, and lymphocytic thyroiditis.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 E05[4-9]
  • Hospital discharge: ICD-9 2423
  • Hospital discharge: ICD-8 2422
  • Cause of death: ICD-10 E05[4-9]
  • Cause of death: ICD-9 2423
  • Cause of death: ICD-8 2422
  • Medicine purchases: ATC H03B

3 out of 7 registries used, show all original rules.

8986

4. Check minimum number of events

Min. number of events 3
8986

5. Include endpoints

None

8986

6. Filter based on genotype QC (FinnGen only)

8986

Control definitions (FinnGen only)

Control exclude
E4_THYROID

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 8986 7039 1947
Unadjusted period prevalence (%) 2.07 2.40 0.86
Median age at first event (years) 53.33 51.46 60.09

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
7934
Matched controls
79340
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
E05
ICD-10 Finland
Thyrotoxicosis [hyperthyroidism]
377.6
323.0
954
29
T86
ICPC
Hypothyroidism/myxoedema
66.7
323.0
501
80
H03BB01
ATC
carbimazole; oral
3756.6
323.0
6207
71
T85
ICPC
Hyperthyroidism/thyrotoxicosis
197.8
323.0
341
18
C07AA05
ATC
propranolol; systemic
4.4
323.0
2945
9326
E05.9
ICD-10 Finland
Thyrotoxicosis, unspecified
4099.2
323.0
4400
24
C07AB07
ATC
bisoprolol; oral
2.7
323.0
4149
23148
BAA60
NOMESCO Finland
Total thyroidectomy
1148.4
323.0
1259
13
E05.80
ICD-10 Finland
Subacute thyrotoxicosis
560.4
323.0
855
17
E03.89
ICD-10 Finland
Other specified hypothyroidism
139.0
323.0
471
36
H06.2*E05.9
ICD-10 Finland
Dysthyroid exophthalmos
+∞
323.0
677
*
E89.01
ICD-10 Finland
Postsurgical hypothyroidism
2002.8
323.0
855
5
E89.00
ICD-10 Finland
Postirradiation hypothyroidism
+∞
323.0
829
*
E05.89
ICD-10 Finland
Other thyrotoxicosis
2006.1
323.0
402
*
E05.2
ICD-10 Finland
Thyrotoxicosis with toxic multinodular goitre
1724.6
323.0
1035
7
H03AA01
ATC
levothyroxine sodium; systemic
123.7
323.0
4741
939
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
123.5
323.0
1404
138
104
Kela drug reimbursment
Thyroid insufficiency
917.0
323.0
1672
23
E03
ICD-10 Finland
Other hypothyroidism
70.1
323.0
639
99
BA1AE
NOMESCO Finland
Thyroiid ultrasound examination
33.9
323.0
568
180
E05.0
ICD-10 Finland
Thyrotoxicosis with diffuse goitre
11811.3
323.0
4198
7
E04.2
ICD-10 Finland
Nontoxic multinodular goitre
39.0
323.0
415
112
XX7CT
NOMESCO Finland
Radioiodine therapy of thydoid tissue
1517.3
323.0
559
*
EP1AE
NOMESCO Finland
Neck ultrasound examination
6.2
277.2
805
1424
E03.2
ICD-10 Finland
Hypothyroidism due to medicaments and other exogenous substances
2295.4
241.6
233
*
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
28.6
239.2
330
120
H06.2
ICD-10 Finland
Dysthyroid exophthalmos
2242.8
236.4
228
*
E03.80
ICD-10 Finland
Hypothyroidism caused by autoimmune thyroiditis
109.6
214.4
234
22
C01BD01
ATC
amiodarone; systemic
8.8
209.5
470
563
H062, E050
ICD-10 Finland
NA
+∞
196.6
188
*
E05.1
ICD-10 Finland
Thyrotoxicosis with toxic single thyroid nodule
+∞
189.3
181
*
E04.9
ICD-10 Finland
Nontoxic goitre, unspecified
22.4
173.0
256
118
BA3AT
NOMESCO Finland
Cytology of thyroid with ultrasound quidance
15.9
152.1
254
165
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.9
144.9
2780
17240
H03BA02
ATC
propylthiouracil; oral
+∞
136.8
131
*
24220
ICD-8 Finland
Thyrotoxicosis with or without goitre, Thyrotoxicosis without mention of goitre
+∞
129.5
124
*
E89.09
ICD-10 Finland
Postprocedural hypothyroidism, other or several procedures
633.1
126.7
125
*
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
5.1
124.3
419
865
E05.4
ICD-10 Finland
Thyrotoxicosis factitia
+∞
121.1
116
*
I48
ICD-10 Finland
Atrial fibrillation and flutter
2.1
117.1
1517
7919
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.8
116.9
3319
23029
CA1BG
NOMESCO Finland
Eye and orbita MRI examination with high intensity magnet
30.5
111.1
150
50
TFP20
NOMESCO Finland
Cardiodefibrillation
3.3
110.3
617
2005
E89.2
ICD-10 Finland
Postprocedural hypoparathyroidism
97.3
104.2
115
12
E06.1
ICD-10 Finland
Subacute thyroiditis
+∞
103.3
99
*
C73.91
ICD-10 Finland
Papillary carcinoma of the thyroid gland (thyroid gland)
48.0
100.6
123
26
E06.3
ICD-10 Finland
Autoimmune thyroiditis
44.6
99.2
123
28
E04.0
ICD-10 Finland
Nontoxic diffuse goitre
67.0
91.7
106
16
207
Kela drug reimbursment
Chronic arrhythmias
2.2
91.1
1012
4880
8260/3-C73.9
ICD-O-3
Papillary adenocarcinoma, NOS, of thyroid gland
111.4
91.1
99
9
BAA40
NOMESCO Finland
Unilateral lobectomy of thyroid gland
15.8
89.6
149
96
H05.2
ICD-10 Finland
Exophthalmic conditions
36.5
83.7
108
30
E05.5
ICD-10 Finland
Thyroid crisis or storm
+∞
83.5
80
*
E04.1
ICD-10 Finland
Nontoxic single thyroid nodule
26.5
82.3
115
44
H02AB06
ATC
prednisolone; systemic
1.6
79.9
3455
25995
E03.0
ICD-10 Finland
Congenital hypothyroidism with diffuse goitre
+∞
78.2
75
*
C07AB02
ATC
metoprolol; systemic
1.8
76.6
1448
8571
E06.9
ICD-10 Finland
Thyroiditis, unspecified
56.9
76.0
90
16
C07AA07
ATC
sotalol; systemic
3.7
72.0
338
953
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
70.3
2938
21697
E89.0
ICD-10 Finland
Postprocedural hypothyroidism
+∞
65.7
63
*
24199
ICD-8 Finland
Non-toxic nodular goitre, Unspecified
+∞
62.6
60
*
B01AA03
ATC
warfarin; systemic
1.8
61.0
1205
7178
BAA25
NOMESCO Finland
Bilateral partial excision of thyroid gland
+∞
60.5
58
*
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
2.0
59.6
895
4840
ZXE10
NOMESCO Finland
More than one and less than three hours
1.5
57.5
2611
19403
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.6
57.0
1587
10452
C03CA01
ATC
furosemide; systemic
1.6
56.1
1715
11571
E06.2
ICD-10 Finland
Chronic thyroiditis with transient thyrotoxicosis
+∞
55.3
53
*
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
5.5
54.5
168
313
TFP46
NOMESCO Finland
Ablation treatment of atrial fibrillation
5.4
54.3
169
319
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
9.0
54.0
117
132
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.7
54.0
1342
8548
E06.4
ICD-10 Finland
Drug-induced thyroiditis
+∞
51.1
49
*
A11CC03
ATC
alfacalcidol; systemic
4.3
50.9
195
459
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.9
50.8
771
4174
A02BC02
ATC
pantoprazole; systemic
1.4
50.6
4647
39433
R00.2
ICD-10 Finland
Palpitations
2.1
50.2
586
2852
TFP34
NOMESCO Finland
Electrophysiological investigation
3.4
49.9
256
775
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.7
49.8
1110
6831
2420A
ICD-9 Finland
Thyrotoxicosis with or without goitre, Toxic diffuse goitre
+∞
49.0
47
*
C01AA05
ATC
digoxin; systemic
2.3
48.7
496
2267
CA1AD
NOMESCO Finland
Orbita CT
27.0
48.5
67
25
CAC30
NOMESCO Finland
Decompression of orbit to sinuses
480.7
48.4
48
*
I50.9
ICD-10 Finland
Heart failure, unspecified
1.9
48.3
750
4090
XF400
NOMESCO Finland
ECG with 12 standard connections
1.7
47.9
1060
6504
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
2.4
45.9
417
1803
R53
ICD-10 Finland
Malaise and fatigue
1.6
45.6
1408
9458
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.8
45.4
831
4793
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
44.4
1842
13254
106
Kela drug reimbursment
Hypoparathyroidism
28.8
44.3
60
21
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
2.4
44.1
395
1694
N02BE01
ATC
paracetamol; systemic, rectal
1.5
43.5
6445
58936
H53.2
ICD-10 Finland
Diplopia
3.0
43.2
256
860
R94.6
ICD-10 Finland
Abnormal results of thyroid function studies
13.2
43.0
76
58
H04.10
ICD-10 Finland
Dry eye syndrome
1.8
42.5
745
4232
TPH04
NOMESCO Finland
Cathetrisation of vein
1.6
42.5
1391
9459
2505
FHL
Bilateral resection (also used if total removal has been performed on the other side)
38.1
41.8
53
14
C01BC04
ATC
flecainide; systemic
2.9
41.7
269
957
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.6
41.1
1106
7149
TFP35
NOMESCO Finland
Electroanatomical mapping
4.8
40.9
140
295
R00.0
ICD-10 Finland
Tachycardia, unspecified
2.5
39.9
326
1331
TFC25
NOMESCO Finland
Transseptal catheterisation of left atrium or ventricle
5.0
39.7
130
261
H50.2
ICD-10 Finland
Vertical strabismus
6.9
39.7
101
148
I47.2
ICD-10 Finland
Ventricular tachycardia
3.8
39.3
171
454
ZXD10
NOMESCO Finland
Scheduled procedure
1.4
39.2
2709
21449
E83.51
ICD-10 Finland
Hypocalcemia
11.0
38.9
75
69
ZXE00
NOMESCO Finland
One hour or less
1.4
38.8
2822
22530
H03BB02
ATC
thiamazole; oral
137.3
38.7
41
*
XF404
NOMESCO Finland
Ambulatory ECG
1.9
38.1
611
3359
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
37.7
1866
13849
ZXA10
NOMESCO Finland
Bilateral
1.5
36.6
1246
8523
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
2.4
36.0
308
1291
Z3231
NOMESCO Finland
Registered nurse
1.4
35.6
1818
13554
BAA50
NOMESCO Finland
Lobectomy and resection of contralateral lobe of thyroid gland
180.7
34.8
36
*
SPAT1249
SPAT
Treatment-related counselling outside office
1.4
34.7
2744
22107
CAC44
NOMESCO Finland
Combined decompression of orbit
+∞
34.4
33
*
H02AB07
ATC
prednisone; oral
1.6
33.8
975
6392
C03DA01
ATC
spironolactone; oral
1.8
33.8
631
3651
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.5
32.5
1131
7751
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
2.4
32.2
280
1184
R06.0
ICD-10 Finland
Dyspnoea
1.4
32.0
1547
11371
K80
ICPC
Cardiac arrhythmia NOS
1.9
31.5
500
2736
XCW99
NOMESCO Finland
Other investigative procedure of eye
1.7
30.8
692
4232
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
2.1
30.8
375
1855
H02AB09
ATC
hydrocortisone; systemic
3.4
30.6
151
446
B01AF02
ATC
apixaban; oral
1.8
30.6
555
3179
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
2.5
29.7
249
1033
K04
ICPC
Palpitations/awareness of heart
2.1
29.6
366
1820
K78
ICPC
Atrial fibrillation/flutter
1.9
29.6
427
2258
ZX120
NOMESCO Finland
Intravenous
1.7
29.3
622
3741
XCK00
NOMESCO Finland
Perimetry
1.9
29.2
444
2391
2423X
ICD-9 Finland
Thyrotoxicosis with or without goitre, Toxic nodular goitre, unspecified
+∞
29.2
28
*
WX402
NOMESCO Finland
General anaesthesia
1.5
29.2
1096
7631
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
29.1
1347
9795
SPAT1262
SPAT
Handing over of treatment supplies
1.5
29.0
1055
7292
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
2.8
28.2
186
673
E07.9
ICD-10 Finland
Disorder of thyroid, unspecified
18.8
28.2
43
23
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
1.9
27.8
425
2294
R07.4
ICD-10 Finland
Chest pain, unspecified
1.4
27.2
1618
12315
R03AC02
ATC
salbutamol; inhalant
1.3
26.8
3651
31488
J01DB01
ATC
cefalexin; oral
1.3
26.7
5947
54867
H04AA01
ATC
glucagon; nasal, parenteral
2.9
26.5
165
577
D44.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Thyroid gland
5.7
26.4
77
137
T89
ICPC
Diabetes insulin dependent
2.4
26.1
234
1005
E05.3
ICD-10 Finland
Thyrotoxicosis from ectopic thyroid tissue
+∞
26.0
25
*
XCK10
NOMESCO Finland
Photography of fundus of eye
1.7
25.6
598
3694
XCD10
NOMESCO Finland
Electrophysiological examination of eye
2.7
25.3
177
665
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.4
25.1
1531
11674
JN5PN
NOMESCO Finland
Isotope imaging of secondary neoplasms of thyroid origin
+∞
25.0
24
*
M14.5*E03.9
ICD-10 Finland
Arthropathy in hypothyroidism (E00-E03+)
+∞
25.0
24
*
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.3
24.9
1992
15879
WX110
NOMESCO Finland
Local anesthesy
1.3
24.8
4881
43980
CAC20
NOMESCO Finland
Lateral decompression of orbit
250.9
24.7
25
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.3
24.4
2396
19674
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
2.1
24.3
293
1444
I42.0
ICD-10 Finland
Dilated cardiomyopathy
2.8
24.2
160
579
B01AB05
ATC
enoxaparin; parenteral
1.3
24.1
1934
15412
AA1AD
NOMESCO Finland
CT of head and brain
1.4
23.8
1365
10293
201
Kela drug reimbursment
Chronic cardiac insufficiency
2.2
23.7
250
1163
CBK00
NOMESCO Finland
Myotomy or resection of tarsal muscle or levator muscle of eyelid for correction of retraction
87.0
23.6
26
*
A04
ICPC
Weakness/tiredness general
1.5
23.6
811
5515
C09AA05
ATC
ramipril; oral
1.4
23.4
1328
9991
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.5
23.1
784
5319
M14.5*E05.9
ICD-10 Finland
Arthropathy in thyrotoxicosis [hyperthyroidism]
+∞
22.9
22
*
24209
ICD-8 Finland
Thyrotoxicosis with or without goitre, Cum struma diffuse NUD
+∞
22.9
22
*
SPAT1263
SPAT
Sampling
1.3
22.8
2822
23859
I50.1
ICD-10 Finland
Left ventricular failure
2.2
22.8
236
1089
O90.5
ICD-10 Finland
Postpartum thyroiditis
83.7
22.7
25
*
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.3
22.6
3765
33026
A10AE04
ATC
insulin glargine; parenteral
1.7
22.1
489
2971
G73.0*E05.9
ICD-10 Finland
Myasthenic syndromes in thyrotoxicosis [hyperthyroidism]
+∞
21.9
21
*
E05.8
ICD-10 Finland
Other thyrotoxicosis
+∞
21.9
21
*
A11CC02
ATC
dihydrotachysterol; oral
15.3
21.4
35
23
XW1AT
NOMESCO Finland
Biopsy from other organ close to skin with ultrasound quidance
5.5
21.3
63
115
J01AA02
ATC
doxycycline; systemic
1.3
21.3
5578
51525
H50.8
ICD-10 Finland
Other specified strabismus
17.4
21.3
33
19
XF402
NOMESCO Finland
ECG with work load test
1.6
21.2
605
3936
N05BA04
ATC
oxazepam; oral
1.3
21.2
1614
12718
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.3
21.0
1797
14408
H50.6
ICD-10 Finland
Mechanical strabismus
24.2
20.8
29
12
BAA20
NOMESCO Finland
Unilateral partial excision of thyroid gland
24.2
20.8
29
12
A02BC01
ATC
omeprazole; systemic
1.3
20.7
1725
13771
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
2.7
20.6
144
543
E34.9
ICD-10 Finland
Endocrine disorder, unspecified
9.0
20.5
43
48
A02BC05
ATC
esomeprazole; systemic
1.3
20.4
2658
22520
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
1.7
20.4
421
2508
AR6
HP
Catheter ablation of arrhythmia, target: atrial fibrillation
7.1
20.2
49
69
I50.0
ICD-10 Finland
Congestive heart failure
1.8
20.2
336
1870
T81
ICPC
Goitre
10.9
20.1
38
35
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.4
20.0
1072
7962
A10AE05
ATC
insulin detemir; parenteral
1.9
20.0
309
1674
N05CF01
ATC
zopiclone; oral
1.3
20.0
2014
16499
I10
ICD-10 Finland
Essential (primary) hypertension
1.2
19.8
3442
30154
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.4
19.8
1284
9852
GB1AA
NOMESCO Finland
Tracheal X-ray examination
73.6
19.7
22
*
E06.0
ICD-10 Finland
Acute thyroiditis
24.6
19.5
27
11
I48.1
ICD-10 Finland
Persistent atrial fibrillation
2.5
19.4
151
605
WX892
NOMESCO Finland
Monitored bed care
1.7
19.2
428
2604
AQ2
HP
Electrophysiological electroanatomical examination
6.8
19.2
48
71
I42.9
ICD-10 Finland
Cardiomyopathy, unspecified
3.1
19.1
107
351
BBA70
NOMESCO Finland
Implantation or transplantation of parathyroid gland
20.1
19.0
28
14
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
2.1
18.8
215
1039
E03.82
ICD-10 Finland
Hypothyroidism caused by autoimmune thyroiditis
+∞
18.8
18
*
2429X
ICD-9 Finland
Thyrotoxicosis with or without goitre, Thyrotoxicosis without mention of goitre or other cause
70.0
18.7
21
*
FPG30
NOMESCO Finland
Implantation of cardioverter-defibrillator with ventricular electrode
6.0
18.7
51
85
342
Kela drug reimbursment
Dronedarone
4.4
18.6
68
157
K90.0
ICD-10 Finland
Coeliac disease
2.2
18.6
192
888
A10AB04
ATC
insulin lispro; parenteral (insulins and analog. for injection, fast-acting)
2.2
18.6
195
909
E05.81
ICD-10 Finland
Overproduction of thyroid-stimulating hormone
190.4
18.5
19
*
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
1.7
18.5
401
2423
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.4
18.5
960
7083
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.4
18.4
1015
7572
N02AX02
ATC
tramadol; systemic, rectal
1.3
18.3
2621
22387
FPG32
NOMESCO Finland
Implantation of cardioverter-defibrillator with atrial and ventricular electrodes
4.9
18.3
59
120
Z2221
NOMESCO Finland
Medical doctor
1.3
18.1
1872
15347
J45.9
ICD-10 Finland
Asthma, unspecified
1.4
18.0
1077
8143
E10
ICD-10 Finland
Type 1 diabetes mellitus
2.8
17.9
114
406
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.3
17.9
1503
11977
2504
FHL
Unilateral resection or enucleation
10.7
17.9
34
32
ZXE20
NOMESCO Finland
More than three and less than five hours
1.4
17.8
788
5643
R11
ICD-10 Finland
Nausea and vomiting
1.6
17.7
483
3105
CEC00
NOMESCO Finland
Recession of extraocular muscle
6.0
17.6
48
80
A10AA01
ATC
NA
2.3
17.6
166
734
K02.1
ICD-10 Finland
Caries of dentine
1.2
17.5
3809
34035
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.2
17.4
3222
28287
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
1.6
17.4
437
2751
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.4
17.3
1008
7586
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.4
17.2
916
6782
ZXD05
NOMESCO Finland
Urgent procedure
1.3
17.1
2004
16675
I47.1
ICD-10 Finland
Supraventricular tachycardia
1.9
17.0
259
1401
SPAT1097
SPAT
Recording of ECG
1.4
16.9
828
6040
E07.89
ICD-10 Finland
Other specified disorders of thyroid
25.6
16.9
23
9
SPAT1301
SPAT
No procedures
1.3
16.9
1943
16132
Z01.7
ICD-10 Finland
Laboratory examination
1.5
16.8
663
4638
R50.9
ICD-10 Finland
Fever, unspecified
1.4
16.8
783
5660
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.2
16.7
3408
30181
24200
ICD-8 Finland
Thyrotoxicosis with or without goitre, Cum struma diffusa et exophthalmo. Morbus Basedowi
+∞
16.7
16
*
XF600
NOMESCO Finland
Bloodpressure measurement
1.7
16.6
349
2092
B03BA03
ATC
hydroxocobalamin; parenteral
1.8
16.6
279
1561
TFP47
NOMESCO Finland
Ablation or modification of the AV-node
5.1
16.6
52
103
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.5
16.6
679
4786
E03.8
ICD-10 Finland
Other specified hypothyroidism
90.2
16.5
18
*
B01AF01
ATC
rivaroxaban; oral
1.5
16.5
612
4228
SAA01
NOMESCO Finland
Simple examination of mouth
1.2
16.4
4916
45278
I49.3
ICD-10 Finland
Ventricular premature depolarization
1.6
16.3
392
2439
Z3226
NOMESCO Finland
Physiotherapist
1.3
16.2
1131
8760
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
2.5
16.1
128
522
E20.8
ICD-10 Finland
Other hypoparathyroidism
30.1
16.1
21
7
C01BD07
ATC
dronedarone; oral
4.6
16.1
55
120
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.3
16.0
2093
17623
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.4
16.0
765
5554
H3600, E103
ICD-10 Finland
NA
3.3
16.0
80
244
N06AX11
ATC
mirtazapine; oral
1.3
15.8
1976
16546
8341/3-C73.9
ICD-O-3
Papillary microcarcinoma of thyroid gland
60.1
15.7
18
*
N05AN01
ATC
lithium; oral
2.4
15.7
131
547
R13
ICD-10 Finland
Dysphagia
1.7
15.7
338
2039
BA1AN
NOMESCO Finland
Thyroid gland isotope imaging
+∞
15.6
15
*
E89.9
ICD-10 Finland
Postprocedural endocrine and metabolic disorder, unspecified
+∞
15.6
15
*
2419X
ICD-9 Finland
Non-toxic nodular goitre, Unspecified non-toxic nodular goitre
+∞
15.6
15
*
J01CA04
ATC
amoxicillin; systemic
1.2
15.6
5848
54983
R60.0
ICD-10 Finland
Localized oedema
1.5
15.6
609
4248
I49.5
ICD-10 Finland
Sick sinus syndrome
2.0
15.5
187
926
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
2.8
15.5
98
351
G47.3
ICD-10 Finland
Sleep apnoea
1.3
15.5
1060
8175
CEC90
NOMESCO Finland
Total transposition of extraocular muscle or muscles
160.3
15.5
16
*
177
Kela drug reimbursment
Insulin glargine 300 U / ml
2.6
15.5
109
416
E04.8
ICD-10 Finland
Other specified nontoxic goitre
13.7
15.5
26
19
AQ1
HP
Conventional electrophysiological examination
3.2
15.4
81
256
103
Kela drug reimbursment
Diabetes, insulin-treated
1.3
15.4
1357
10859
A10AA02
ATC
NA
2.0
15.4
190
950
Z71.8
ICD-10 Finland
Other specified counselling
1.3
15.3
1510
12268
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.4
15.3
747
5444
O24.0
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, insulin-dependent
2.7
15.2
104
390
E21.09
ICD-10 Finland
Other primary hyperparathyroidism
2.5
15.1
117
470
CA1BM
NOMESCO Finland
Eye and orbita MRI examination with 3 Tesla magnet
45.1
15.0
18
*
R06AE07
ATC
cetirizine; oral
1.2
14.9
2995
26380
UDQ12
NOMESCO Finland
Flexible laryngoscopy
1.7
14.9
296
1745
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.3
14.8
1436
11631
R63.4
ICD-10 Finland
Abnormal weight loss
2.0
14.7
189
960
R02
ICPC
Shortness of breath/dyspnoea
1.4
14.7
672
4839
R51.80
ICD-10 Finland
Headache
1.4
14.6
899
6817
JN5AQ
NOMESCO Finland
SPECT of thyroid metastasis with low-dose CT
+∞
14.6
14
*
I49.8
ICD-10 Finland
Other specified cardiac arrhythmias
2.1
14.5
167
811
L28
ICPC
Limited function/disability (L)
1.4
14.4
845
6353
R01AD08
ATC
fluticasone; nasal
1.3
14.4
1831
15333
C08CA01
ATC
amlodipine; oral
1.2
14.4
1921
16179
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.2
14.3
2966
26175
R42
ICD-10 Finland
Dizziness and giddiness
1.3
14.3
1274
10205
WX002
NOMESCO Finland
Sedation and analgesia
1.3
14.2
1162
9196
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.3
14.2
1137
8970
M25.5
ICD-10 Finland
Pain in joint
1.3
14.1
1788
14957
J01FA10
ATC
azithromycin; systemic
1.2
14.1
4044
36798
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.2
14.1
1830
15351
M79.6
ICD-10 Finland
Pain in limb
1.2
14.0
2255
19377
J01DA01
ATC
[U] cefalexin; systemic
1.2
14.0
4331
39689
289
Kela drug reimbursment
Combination product containing sacubitril and valsartan
4.1
14.0
53
129
R07.0
ICD-10 Finland
Pain in throat
1.6
13.9
353
2230
UJF32
NOMESCO Finland
Coloscopy
1.3
13.9
1482
12140
SPAT1255
SPAT
Intravenous administration of medicine
1.6
13.9
343
2154
AN1
HP
Coronary angiography
1.5
13.8
529
3676
R00.1
ICD-10 Finland
Bradycardia, unspecified
2.1
13.7
152
726
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.2
13.7
2571
22437
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.3
13.7
946
7304
C09DX04
ATC
valsartan and sacubitril; oral
4.3
13.6
49
114
2411A
ICD-9 Finland
Non-toxic nodular goitre, Non-toxic multinodular goitre
+∞
13.5
13
*
K29.4
ICD-10 Finland
Chronic atrophic gastritis
2.4
13.5
108
445
2AB04
NOMESCO Finland
NA
7.1
13.5
32
45
WF099
NOMESCO Finland
Other radiotherapy
4.7
13.4
45
97
FJA10
NOMESCO Finland
Transvenous biopsy of right ventricle
4.5
13.4
47
106
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
1.5
13.4
402
2649
R03BB04
ATC
tiotropium bromide; inhalant
1.5
13.4
477
3264
E89.1
ICD-10 Finland
Postprocedural hypoinsulinaemia
25.8
13.3
18
7
R01AD09
ATC
mometasone; nasal
1.2
13.3
3011
26736
CA1BD
NOMESCO Finland
Extensive orbita CT
13.8
13.2
22
16
I49.0
ICD-10 Finland
Ventricular fibrillation and flutter
3.9
12.9
52
134
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.3
12.9
918
7115
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.2
12.8
1594
13287
E50.0
ICD-10 Finland
Vitamin A deficiency with conjunctival xerosis
50.1
12.8
15
*
SGA01
NOMESCO Finland
Tooth opening as first aid
1.3
12.7
930
7235
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.3
12.7
1418
11675
N03AX16
ATC
pregabalin; oral
1.3
12.7
1379
11313
GD1LA
NOMESCO Finland
GD
2.7
12.7
85
318
1CX08
NOMESCO Finland
NA
6.0
12.7
34
57
Z01.9
ICD-10 Finland
Special examination, unspecified
1.6
12.6
309
1933
C08DA01
ATC
verapamil; systemic
1.8
12.6
230
1324
WX290
NOMESCO Finland
Other blockade of nerve
1.2
12.6
2841
25190
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.5
12.5
419
2830
B81
ICPC
Anaemia vit B12/folate deficiency
1.9
12.5
178
941
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
1.5
12.5
456
3137
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
1.5
12.4
504
3543
BWD00
NOMESCO Finland
Reoperation for deep haemorrhage in endocrine surgery
130.2
12.4
13
*
SPAT1312
SPAT
General health counselling
1.2
12.4
2013
17272
H3601, E103
ICD-10 Finland
NA
3.3
12.4
60
181
M54.5
ICD-10 Finland
Low back pain
1.2
12.2
2048
17619
TFP44
NOMESCO Finland
Ablation treatment of typical atrial flutter
3.5
12.2
56
162
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
1.5
12.1
439
3017
A10AE06
ATC
insulin degludec; parenteral
2.0
12.0
147
737
H50.0
ICD-10 Finland
Convergent concomitant strabismus
3.6
12.0
52
144
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.4
11.9
602
4413
TFP30
NOMESCO Finland
Cathetric examination for cardiac arrythmia
3.1
11.9
65
214
M03BC51
ATC
orphenadrine, combinations; systemic
1.2
11.9
1798
15298
E06
ICD-10 Finland
Thyroiditis
46.7
11.9
14
*
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
1.5
11.9
399
2700
CEW99
NOMESCO Finland
Other operation on extraocular muscle
10.5
11.7
22
21
H57.1
ICD-10 Finland
Ocular pain
1.8
11.7
185
1017
AR5
HP
Catheter ablation of arrhythmia, target: atrial flutter
6.6
11.7
29
44
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.2
11.7
2871
25602
N02AJ06
ATC
codeine and paracetamol; systemic
1.2
11.6
2285
19952
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.3
11.6
846
6580
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.4
11.5
697
5267
24110
ICD-8 Finland
Non-toxic nodular goitre, Sporadic
+∞
11.5
11
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.3
11.4
1171
9525
A06AC01
ATC
ispaghula (psylla seeds); oral
1.2
11.4
1432
11930
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.2
11.4
3807
34825
D64.9
ICD-10 Finland
Anaemia, unspecified
1.4
11.4
475
3356
R03BA02
ATC
budesonide; inhalant
1.3
11.3
1071
8622
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.3
11.3
1116
9033
FM1DG
NOMESCO Finland
Very extensive MRI examination of heart with high intesity magnet
2.7
11.3
73
268
H02.5
ICD-10 Finland
Other disorders affecting eyelid function
6.0
11.3
30
50
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.5
11.3
392
2671
E23.05
ICD-10 Finland
Lack of TSH
15.0
11.3
18
12
L01
ICPC
Neck symptom/complaint
1.3
11.3
806
6247
A12BA01
ATC
potassium chloride; oral
1.7
11.3
222
1312
R21
ICPC
Throat symptom/complaint
1.3
11.2
1220
9996
381
Kela drug reimbursment
Combination product containing sacubitril and valsartan
4.0
11.2
43
107
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
1.7
11.2
235
1412
N06AB10
ATC
escitalopram; oral
1.3
11.2
1210
9907
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.2
11.2
3467
31505
FPE00
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with ventricular electrode
2.4
11.1
95
405
N05BA12
ATC
alprazolam; oral
1.4
11.1
583
4297
N06AX21
ATC
duloxetine; oral
1.4
11.1
618
4604
R25.1
ICD-10 Finland
Tremor, unspecified
1.9
11.1
148
767
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
1.6
11.0
317
2071
J01FF01
ATC
clindamycin; systemic
1.2
11.0
1611
13654
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.3
10.9
786
6096
G44.2
ICD-10 Finland
Tension-type headache
1.3
10.9
813
6341
R49.08
ICD-10 Finland
Other specified dysphonia
2.1
10.9
125
613
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.3
10.8
1084
8786
SPAT1254
SPAT
Administration of medicine
1.3
10.8
777
6024
ARB
HP
Catheter ablation of arrhythmia: Cutiing or modification of the AV node
11.9
10.8
19
16
I50
ICD-10 Finland
Heart failure
2.0
10.8
142
734
L03
ICPC
Low back symptom/complaint
1.2
10.8
1461
12270
J01FA06
ATC
roxithromycin; oral
1.2
10.7
2617
23267
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.2
10.7
2512
22255
C73.99
ICD-10 Finland
Malignant tumor of the thyroid gland (thyroid gland), other or unspecified histology
28.0
10.7
14
5
E21.3
ICD-10 Finland
Hyperparathyroidism, unspecified
2.8
10.7
67
241
A02BA02
ATC
ranitidine; systemic
1.3
10.7
1101
8960
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
1.7
10.6
203
1187
N06AB04
ATC
citalopram; systemic
1.2
10.6
1293
10735
E83.50
ICD-10 Finland
Hypercalcemia
2.6
10.6
73
280
I49.4
ICD-10 Finland
Other and unspecified premature depolarization
1.7
10.6
194
1123
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.3
10.6
1039
8404
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.2
10.6
1416
11876
M03BX02
ATC
tizanidine; oral
1.2
10.5
4227
39146
K05
ICPC
Irregular heartbeat other
1.9
10.5
158
857
N03AX12
ATC
gabapentin; oral
1.3
10.5
860
6794
SPAT1260
SPAT
Consultation of another employee
1.3
10.5
1018
8224
A29
ICPC
General symptom/complaint other
1.4
10.5
594
4442
E06.5
ICD-10 Finland
Other chronic thyroiditis
110.1
10.4
11
*
WZC30
NOMESCO Finland
Teaching
1.3
10.4
701
5385
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
1.6
10.4
232
1423
R4110
NOMESCO Finland
Physiotherapy
1.2
10.3
1586
13491
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
1.4
10.3
476
3436
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.3
10.3
807
6336
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
3.2
10.2
52
164
7AX01
NOMESCO Finland
NA
23.4
10.2
14
6
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
1.4
10.2
439
3126
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
1.5
10.2
378
2613
E27.1
ICD-10 Finland
Primary adrenocortical insufficiency
7.4
10.1
23
31
N06AB03
ATC
fluoxetine; oral
1.3
10.1
722
5594
FPH10
NOMESCO Finland
Open removal of transvenous cardiac pacemaker or cardioverter-defibrillator
7.9
10.1
22
28
J01FA09
ATC
clarithromycin; systemic
1.2
10.1
2019
17618
A98
ICPC
Health maint/preventive medicine
1.3
10.0
7371
72004
107
Kela drug reimbursment
Pernicious anaemia
2.3
10.0
93
414
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.4
10.0
505
3700
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
1.4
10.0
445
3186
A02BC03
ATC
lansoprazole; oral
1.2
10.0
1720
14792
I48.2
ICD-10 Finland
Chronic atrial fibrillation
2.1
10.0
111
538
WX320
NOMESCO Finland
Spinalanesthesy
1.2
9.9
1324
11093
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.3
9.9
738
5754
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
1.4
9.8
388
2718
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
1.9
9.8
138
733
Z01.2
ICD-10 Finland
Dental examination
1.2
9.8
2621
23444
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
1.4
9.8
457
3302
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.3
9.8
985
7990
C09CA01
ATC
losartan; oral
1.2
9.7
1268
10592
N05AH04
ATC
quetiapine; oral
1.3
9.7
875
6997
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.3
9.7
752
5896
4CJ01
NOMESCO Finland
NA
55.0
9.6
11
*
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.3
9.6
684
5296
H02AB04
ATC
methylprednisolone; systemic
1.3
9.6
850
6785
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.2
9.5
2474
22060
SPAT1310
SPAT
Counselling related to known health issue
1.2
9.4
1922
16779
R96
ICPC
Asthma
1.4
9.4
470
3439
A99
ICPC
Disease/condition unspecnature/site
1.4
9.4
414
2961
W84
ICPC
Pregnancy high risk
1.7
9.4
171
987
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.5
9.4
333
2282
I47.9
ICD-10 Finland
Paroxysmal tachycardia, unspecified
2.1
9.4
100
476
E03.3
ICD-10 Finland
Postinfectious hypothyroidism
100.1
9.4
10
*
BA1AE
SPAT
NA
3.1
9.4
48
153
BA1NN
NOMESCO Finland
I-131 dose capsel measurement
+∞
9.4
9
*
TBA20
NOMESCO Finland
Aspiration cytology of thyroid gland
+∞
9.4
9
*
E03.1
ICD-10 Finland
Congenital hypothyroidism without goitre
+∞
9.4
9
*
J01MA12
ATC
levofloxacin; systemic
1.3
9.4
963
7829
TKC20
NOMESCO Finland
Catheterisation of bladder
1.5
9.2
329
2257
SGA02
NOMESCO Finland
Opening and dilatation of root canal of tooth
1.3
9.2
698
5449
UKC02
NOMESCO Finland
Cystoscopy
1.3
9.2
699
5463
CA1CM
NOMESCO Finland
Eye and orbita extensive MRI examination with 3 Tesla magnet
5.0
9.2
28
56
N05CF02
ATC
zolpidem; oral
1.2
9.2
1040
8548
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.4
9.2
466
3419
FPE20
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with atrial and ventricular electrodes
1.7
9.2
174
1019
R03BA05
ATC
fluticasone; inhalant
1.2
9.2
1071
8839
I34.00
ICD-10 Finland
Mitral (valve) incompetence NOS or of specified cause, except rheumatic
2.1
9.2
98
469
C08DB01
ATC
diltiazem; oral
1.6
9.1
245
1579
TPH07
NOMESCO Finland
Cathetrisation of artery
1.4
9.1
505
3761
CEC10
NOMESCO Finland
Recession and resection of extraocular muscle
3.1
9.1
47
151
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.4
9.1
405
2904
I49.1
ICD-10 Finland
Atrial premature depolarization
1.7
9.1
177
1046
L17
ICPC
Foot/toe symptom/complaint
1.2
9.1
1450
12367
24210
ICD-8 Finland
Thyrotoxicosis with or without goitre, Toxic nodular goitre
8.3
9.0
19
23
A08
ICPC
Swelling
1.6
9.0
216
1350
Z32.1
ICD-10 Finland
Pregnancy confirmed
1.4
9.0
515
3859
C73
ICD-10 Finland
Malignant neoplasm of thyroid gland
18.6
8.9
13
7
N02AA05
ATC
oxycodone; systemic
1.3
8.9
706
5548
H36.00
ICD-10 Finland
Diabetic background retinopathy
2.4
8.9
71
294
R52.9
ICD-10 Finland
Pain, unspecified
1.4
8.9
449
3295
XF640
NOMESCO Finland
NA
1.8
8.8
141
782
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
1.6
8.8
206
1281
D01
ICPC
Abdominal pain/cramps general
1.3
8.8
607
4681
I34.09
ICD-10 Finland
Mitral (valve) insufficiency
1.6
8.8
194
1189
C01DA14
ATC
isosorbide mononitrate; oral
1.3
8.7
626
4853
SAA02
NOMESCO Finland
Basic examination of mouth
1.2
8.7
4347
40655
TFP52
NOMESCO Finland
Ablation treatment of ventricular tachycardia due to structural heart defect
14.0
8.7
14
10
M03BC01
ATC
orphenadrine (citrate); systemic
1.2
8.6
1426
12198
CEC60
NOMESCO Finland
Transposition of extraocular muscle with adjustable suture
7.6
8.6
19
25
R01AD12
ATC
fluticasone furoate; nasal
1.2
8.6
1868
16376
C07AB03
ATC
atenolol; systemic
1.5
8.6
283
1910
ZX114
NOMESCO Finland
Intramuscular
2.3
8.6
75
325
-34
ICPC
Blood test
1.8
8.6
151
867
J03.9
ICD-10 Finland
Acute tonsillitis, unspecified
1.5
8.6
259
1716
R07.3
ICD-10 Finland
Other chest pain
1.4
8.6
489
3660
WZA90
NOMESCO Finland
Other doctors statement
1.2
8.6
1332
11319
L15
ICPC
Knee symptom/complaint
1.2
8.6
1191
10010
R05
ICPC
Cough
1.2
8.5
1326
11272
Z3229
NOMESCO Finland
Other healthcare associate professional
1.4
8.5
444
3274
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
2.6
8.5
58
220
FPE96
NOMESCO Finland
Other implantation or replacement of transvenous cardiac pacemaker
3.8
8.5
34
90
H03AA02
ATC
liothyronine sodium; systemic
20.0
8.5
12
6
P01AB01
ATC
metronidazole; oral, rectal
1.2
8.4
2613
23582
-60
ICPC
Result test/procedure
1.5
8.4
314
2179
2410A
ICD-9 Finland
Non-toxic nodular goitre, Non-toxic uninodular goitre
+∞
8.3
8
*
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.3
8.3
521
3959
N17
ICPC
Vertigo/dizziness
1.3
8.3
591
4576
M79.0
ICD-10 Finland
Rheumatism, unspecified
1.6
8.3
199
1246
M02AA07
ATC
piroxicam; topical
1.2
8.3
2224
19838
FPE30
NOMESCO Finland
Replacement of transvenous cardiac pacemaker pulse generator
2.4
8.3
65
270
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.3
8.3
661
5201
E04
ICD-10 Finland
Other nontoxic goitre
5.2
8.3
24
46
I42.2
ICD-10 Finland
Other hypertrophic cardiomyopathy
3.0
8.3
45
151
WX722
NOMESCO Finland
PEEP
1.6
8.3
202
1271
R55
ICD-10 Finland
Syncope and collapse
1.3
8.3
511
3876
J20
ICD-10 Finland
Acute bronchitis
1.3
8.2
521
3968
PH1AC
NOMESCO Finland
Flebography of over extremity with X-ray
2.4
8.2
64
264
FPG40
NOMESCO Finland
Replacement of pulse generator in transvenous cardioverter-defibrillator
6.5
8.2
20
31
AS7
HP
Arrhythmia pacemaker insertion VVI (R) S
6.5
8.2
20
31
SPAT1283
SPAT
Restricted health certificate
1.2
8.2
1069
8925
C03AA03
ATC
hydrochlorothiazide; oral
1.3
8.1
483
3638
T90
ICPC
Diabetes non-insulin dependent
1.2
8.1
1086
9088
205
Kela drug reimbursment
Chronic hypertension
1.2
8.1
1365
11688
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
1.8
8.1
130
726
S18
ICPC
Laceration/cut
1.2
8.1
2425
21804
XF602
NOMESCO Finland
Bloodpressure monitoring
2.6
8.1
56
216
J01CE02
ATC
phenoxymethylpenicillin; oral
1.1
8.1
4702
44339
WX902
NOMESCO Finland
External defibrillation of heart
4.7
8.1
26
56
F29
ICPC
Eye symptom/complaint other
1.4
8.1
436
3238
O24.4
ICD-10 Finland
Diabetes mellitus arising in pregnancy
1.4
8.1
441
3280
GD6BD
NOMESCO Finland
Extensive CT of chest and neck
6.8
8.0
19
28
G04BE03
ATC
sildenafil; oral
2.7
8.0
52
194
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
1.9
8.0
117
631
FXE00
NOMESCO Finland
Use of ECLA
22.0
8.0
11
5
E66.8
ICD-10 Finland
Other obesity
1.5
8.0
270
1836
SPAT1153
SPAT
Removal of sutures
1.2
8.0
1806
15881
D11
ICPC
Diarrhoea
1.3
8.0
609
4767
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.2
7.9
952
7871
-50
ICPC
Medication/prescr/renewal
1.6
7.9
208
1333
SPAT1104
SPAT
Monitoring of emergency patient
1.4
7.9
329
2329
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.3
7.9
495
3763
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.2
7.9
1934
17121
M79.1
ICD-10 Finland
Myalgia
1.3
7.8
735
5906
FM1CD
NOMESCO Finland
Very extensive CT of heart
4.5
7.8
26
58
I42.1
ICD-10 Finland
Obstructive hypertrophic cardiomyopathy
4.0
7.8
29
72
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
1.8
7.8
121
667
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.3
7.8
636
5018
I63.4
ICD-10 Finland
Cerebral infarction due to embolism of cerebral arteries
1.8
7.8
121
669
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
1.4
7.8
382
2793
J02AC01
ATC
fluconazole; systemic
1.1
7.8
2874
26235
UDH02
NOMESCO Finland
Rhinopharyngoscopy
1.4
7.7
331
2360
C10AA05
ATC
atorvastatin; oral
1.2
7.7
1934
17133
M01AB05
ATC
diclofenac; systemic, rectal
1.1
7.7
4472
42088
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
2.8
7.7
47
171
M01AE03
ATC
ketoprofen; systemic, rectal
1.2
7.7
2277
20445
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
1.5
7.7
230
1526
R35
ICD-10 Finland
Polyuria
1.5
7.6
267
1830
WX882
NOMESCO Finland
High dependency care
1.8
7.6
124
697
UJF30
NOMESCO Finland
Ileoscopy through colon
1.3
7.6
497
3803
A60
ICPC
General and Unspecified, Result test/procedure
1.5
7.6
228
1510
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.3
7.6
615
4851
C73.92
ICD-10 Finland
Follicular carcinoma of the thyroid gland
25.0
7.6
10
*
FPJ21
NOMESCO Finland
Revision of cardioverter-defibrillator with ventricular electrode
8.8
7.5
15
17
105
Kela drug reimbursment
Adrenal cortical hypofunction
5.7
7.5
20
35
SPAT1216
SPAT
Assessment of functional ability
1.3
7.5
774
6294
EN1AD
NOMESCO Finland
CT examination of mouth and soft tissues of neck
2.8
7.5
45
162
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
1.4
7.5
368
2689
N07BA03
ATC
varenicline; oral
1.5
7.4
260
1781
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.3
7.4
481
3675
H50.52
ICD-10 Finland
Exophoria
2.3
7.4
62
266
SPAT1229
SPAT
Assessment of need for aid
1.4
7.4
381
2803
C10AA07
ATC
rosuvastatin; oral
1.2
7.4
1214
10358
N05BA01
ATC
diazepam; systemic, rectal
1.3
7.4
704
5666
M81.0
ICD-10 Finland
Postmenopausal osteoporosis
1.7
7.4
138
806
I46.0
ICD-10 Finland
Cardiac arrest with successful resuscitation
2.4
7.4
60
255
E03.4
ICD-10 Finland
Atrophy of thyroid (acquired)
80.2
7.4
8
*
8330/3-C73.9
ICD-O-3
Follicular carcinoma, NOS, of thyroid gland
80.2
7.4
8
*
8340/3-C73.9
ICD-O-3
Papillary carcinoma, follicular variant of thyroid gland
80.2
7.4
8
*
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
1.4
7.4
294
2069
Z2446
NOMESCO Finland
Social worker
1.4
7.4
323
2313
R03DC03
ATC
montelukast; oral
1.2
7.4
943
7852
CE2W4
NOMESCO Finland
Eye movement mapping
5.3
7.4
21
40
R52.2
ICD-10 Finland
Other chronic pain
1.6
7.3
168
1043
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
1.2
7.3
1961
17461
SPAT1379
SPAT
Health check-up of pregnant person
1.3
7.3
537
4178
2449X
ICD-9 Finland
Acquired hypothyroidism, Unspecified hypothyroidism
+∞
7.3
7
*
2448A
ICD-9 Finland
Acquired hypothyroidism, Other specified acquired hypothyroidism[HYPOTHYREOSIS POST THYREOIDITIDEM]
+∞
7.3
7
*
C10AX09
ATC
ezetimibe; oral
1.3
7.3
477
3654
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
1.7
7.3
135
792
EBA15
NOMESCO Finland
Extraction of large number of teeth
1.7
7.3
154
938
ZYC01
NOMESCO Finland
Remote contact by phone
1.5
7.2
222
1479
J01MA02
ATC
ciprofloxacin; systemic
1.2
7.2
2223
19998
CL2S4
NOMESCO Finland
Ocular fundus photography for diabetic retinopathy screening
2.1
7.2
77
372
T71
ICPC
Malignant neoplasm thyroid
30.0
7.1
9
*
TFP32
NOMESCO Finland
Cathetric treatmen of cardiac arrythmia
2.8
7.1
42
149
I44.2
ICD-10 Finland
Atrioventricular block, complete
1.9
7.1
104
565
F31.0
ICD-10 Finland
Bipolar affective disorder, current episode hypomanic
2.3
7.1
65
290
R60.9
ICD-10 Finland
Oedema, unspecified
1.5
7.1
231
1562
RD210
NOMESCO Finland
NA
1.9
7.1
91
470
TFP45
NOMESCO Finland
Ablation treatment of non-typical atrial flutter
7.9
7.1
15
19
C09AA02
ATC
enalapril; systemic
1.2
7.1
949
7942
CKC12
NOMESCO Finland
Photocoagulation of retina
1.5
7.1
194
1263
A10BA02
ATC
metformin; oral
1.2
7.0
1336
11556
WX872
NOMESCO Finland
Intensive care
1.5
7.0
206
1361
M79.7
ICD-10 Finland
Fibromyalgia
1.6
7.0
181
1159
JN4AD
NOMESCO Finland
Body CT examination
1.4
7.0
348
2547
BEF00
NOMESCO Finland
Continuous subcutaneous glucose monitoring
2.8
7.0
42
151
SGB10
NOMESCO Finland
Fiiling of rooth of tooth with one root channel
1.3
7.0
634
5079
FPB22
NOMESCO Finland
Transvenous radiofrequency ablation of aberrant pathway or focus of heart
4.9
6.9
21
43
D09
ICPC
Nausea
1.5
6.9
211
1406
E21.0
ICD-10 Finland
Primary hyperparathyroidism
2.0
6.9
77
378
A12AA04
ATC
calcium carbonate; oral
2.1
6.9
69
323
XFE00
NOMESCO Finland
Epicardial ultrasonography
1.8
6.9
115
653
SPAT1240
SPAT
Therapeutic discussion
1.3
6.9
584
4635
R5140
NOMESCO Finland
Monitoring the use of the aid
1.3
6.9
461
3543
M04AA01
ATC
allopurinol; systemic
1.3
6.9
494
3834
JC2KB
NOMESCO Finland
Functional X-ray examination of swallowing
2.3
6.9
58
251
I41.8*D86.8
ICD-10 Finland
Sarcoid myocarditis
4.0
6.9
25
62
B01AE07
ATC
dabigatran etexilate; oral
1.6
6.8
168
1065
L02
ICPC
Back symptom/complaint
1.3
6.8
486
3769
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.3
6.8
469
3620
M75.0
ICD-10 Finland
Adhesive capsulitis of shoulder
1.4
6.8
276
1954
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
2.2
6.8
61
274
XKD00
NOMESCO Finland
Uroflowmetry
1.3
6.8
520
4075
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.2
6.8
1650
14573
BAA99
NOMESCO Finland
Other operation on thyroid gland
40.0
6.8
8
*
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.3
6.7
427
3255
WVA40
NOMESCO Finland
Initiation and monitoring of intravenous hydration
2.3
6.7
60
266
F31.7
ICD-10 Finland
Bipolar affective disorder, currently in remission
1.9
6.7
86
445
J45.1
ICD-10 Finland
Nonallergic asthma
1.4
6.7
353
2613
UGC12
NOMESCO Finland
Flexible bronchoscopy
1.4
6.7
330
2415
R4130
NOMESCO Finland
Speech therapy
1.8
6.7
100
548
2506
FHL
Thyroidectomy
22.5
6.7
9
*
A09
ICPC
Sweating problem
2.2
6.7
60
269
K04.0
ICD-10 Finland
Pulpitis
1.3
6.7
502
3923
A13
ICPC
Concern/fear medical treatment
2.0
6.7
81
410
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
2.1
6.6
70
337
R03AK08
ATC
formoterol and beclometasone; inhalant
1.5
6.6
189
1242
FQA10
NOMESCO Finland
Orthotopic transplantation of heart with bicaval anastomosis
7.8
6.6
14
18
Z03.8
ICD-10 Finland
Observation for other suspected diseases and conditions
1.5
6.6
213
1440
FXF00
NOMESCO Finland
Decannulation after ECHLA or ECLA
12.2
6.6
11
9
A03
ICPC
Fever
1.2
6.5
875
7320
SPAT1281
SPAT
Other administrative function
1.3
6.5
402
3052
CS494
NOMESCO Finland
Other visual field testing
1.8
6.5
106
600
R49.01
ICD-10 Finland
Functional dysphonia
1.6
6.5
146
906
M01AE02
ATC
naproxen; oral, rectal
1.1
6.5
3739
35009
ZXE40
NOMESCO Finland
More than seven and less than nine hours
1.7
6.5
113
651
L08
ICPC
Shoulder symptom/complaint
1.2
6.4
1009
8574
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
2.1
6.4
69
336
C73.90
ICD-10 Finland
Malignant tumor of the thyroid gland (thyroid gland) without histology
69.9
6.4
7
*
2441A
ICD-9 Finland
Acquired hypothyroidism, Other postablative hypothyroidism
69.9
6.4
7
*
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.2
6.4
843
7037
A28
ICPC
Limited function/disability NOS
1.2
6.4
688
5618
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
1.3
6.4
595
4779
D34
ICD-10 Finland
Benign neoplasm of thyroid gland
3.3
6.4
29
87
E66.01
ICD-10 Finland
Obesity due to excess calories
1.3
6.4
407
3104
J37.0
ICD-10 Finland
Chronic laryngitis
1.6
6.4
155
978
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.3
6.4
501
3938
I25.2
ICD-10 Finland
Old myocardial infarction
1.5
6.4
235
1629
EP2AT
NOMESCO Finland
Neck soft tissue cytology with ultrasound guidance
4.7
6.4
20
43
I20.99
ICD-10 Finland
Angina pectoris, unspecified
1.4
6.4
259
1833
ZXA05
NOMESCO Finland
Left side
1.2
6.4
1404
12294
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
1.5
6.4
177
1159
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.4
6.4
346
2577
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
1.5
6.3
186
1232
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.3
6.3
636
5152
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
2.5
6.3
46
186
R31
ICD-10 Finland
Unspecified haematuria
1.3
6.3
376
2839
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
1.4
6.3
247
1738
BBA30
NOMESCO Finland
Excision of lesion of parathyroid gland
2.2
6.3
60
277
FPD00
NOMESCO Finland
Maze procedure for atrial fibrillation
9.2
6.3
12
13
E50.9
ICD-10 Finland
Vitamin A deficiency, unspecified
9.2
6.3
12
13
A91
ICPC
Abnormal result investigation NOS
1.5
6.3
200
1348
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.3
6.3
542
4315
E8901, E050
ICD-10 Finland
NA
+∞
6.2
6
*
BA1MN
NOMESCO Finland
Thyroid gland isotope imaging with calculation
+∞
6.2
6
*
I43.8*E05.9
ICD-10 Finland
Thyrotoxic heart disease
+∞
6.2
6
*
O992, E050
ICD-10 Finland
NA
+∞
6.2
6
*
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
1.3
6.2
355
2664
TDM10
NOMESCO Finland
Puncture of maxillary antrum
1.5
6.2
195
1309
2422A
ICD-9 Finland
Thyrotoxicosis with or without goitre, Toxic multinodular goitre
26.7
6.2
8
*
P74
ICPC
Anxiety disorder/anxiety state
1.5
6.2
180
1190
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.2
6.2
1446
12713
F31.20
ICD-10 Finland
Bipolar disorder, manic episode with mood-congruent psychotic symptoms
2.5
6.2
45
182
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.2
6.2
1103
9482
ZXA00
NOMESCO Finland
Right side
1.2
6.2
1505
13276
F31.1
ICD-10 Finland
Bipolar affective disorder, current episode manic without psychotic symptoms
2.5
6.2
44
174
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
1.2
6.2
676
5535
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
1.4
6.2
299
2183
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
1.4
6.2
318
2350
FM1JR
NOMESCO Finland
Heart, extensive metabolic PET with CT
5.0
6.2
18
36
WX100
NOMESCO Finland
Conjunctival surface anesthesia
1.3
6.2
509
4028
3A064
NOMESCO Finland
NA
3.8
6.1
24
64
SFA40
NOMESCO Finland
Replacement of krone of tooth
1.2
6.1
1123
9674
I11.0
ICD-10 Finland
Hypertensive heart disease with (congestive) heart failure
1.8
6.1
99
557
T72
ICPC
Benign neoplasm thyroid
5.7
6.1
16
28
L84
ICD-10 Finland
Corns and callosities
1.6
6.1
154
985
K60
ICPC
Cardiovascular, Result test/procedure
2.6
6.1
41
159
K30
ICD-10 Finland
Functional dyspepsia
1.3
6.1
572
4597
O99.89
ICD-10 Finland
Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
1.8
6.1
97
543
E23.00
ICD-10 Finland
Panhypopituitarism
7.7
6.1
13
17
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
1.5
6.1
168
1098
A50
ICPC
General and Unspecified, Medication/prescr/renewal
1.6
6.1
152
968
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
1.5
6.1
204
1391
P03
ICPC
Feeling depressed
1.3
6.1
473
3715
D05.0
ICD-10 Finland
Lobular carcinoma in situ
4.2
6.1
21
50
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.2
6.1
674
5524
F31.30
ICD-10 Finland
Bipolar disorder Depressive episode without somatic syndrome
1.9
6.1
83
441
M01AB55
ATC
diclofenac, combinations; oral
1.3
6.1
351
2640
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
2.5
6.1
44
178
R22.1
ICD-10 Finland
Localized swelling, mass and lump, neck
1.5
6.1
172
1132
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
1.4
6.0
226
1576
I25.0
ICD-10 Finland
Atherosclerotic cardiovascular disease, so described
1.5
6.0
210
1443
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
1.4
6.0
233
1636

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: E4_THYTOXNAS – Thyrotoxicosis, other and/or unspecified

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).