No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersNone 0 out of 7 registries used, show all original rules. |
0 |
4. Check minimum number of eventsNone |
0 |
5. Include endpoints |
2826 |
6. Filter based on genotype QC (FinnGen only) |
2826 |
Control definitions (FinnGen only)
- Control exclude
- THYROID_DISORDER_IBD
Extra metadata
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Thyroiditis
based on the number of shared cases.
Similar with more cases:
- Disorders of thyroid, IBD co-morbidities
- Disorders of the thyroid gland
- Used for control exclusion in common control thyroid runs
- Endocrine, nutritional and metabolic diseases
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 19571 | 15459 | 3979 |
| Only index persons | 17896 | 14316 | 3580 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.37 | 0.44 | 0.11 |
| Only index persons | 0.45 | 0.53 | 0.14 |
| Median age at first event (years) | |||
| Whole population | 45.67 | 45.04 | 48.17 |
| Only index persons | 44.76 | 44.12 | 47.30 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2826 | 2329 | 497 |
| Unadjusted period prevalence (%) | 0.69 | 0.79 | 0.22 |
| Median age at first event (years) | 45.85 | 44.88 | 50.42 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 2521
- Matched controls
- 25208
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
E06.1
ICD-10 Finland
Subacute thyroiditis
+∞
323.0
989
*
H03AA01
ATC
levothyroxine sodium; systemic
6.0
323.0
1349
4051
E06.9
ICD-10 Finland
Thyroiditis, unspecified
925.1
323.0
392
5
H03BB01
ATC
carbimazole; oral
124.6
323.0
363
34
E06.3
ICD-10 Finland
Autoimmune thyroiditis
416.2
323.0
600
19
E05.9
ICD-10 Finland
Thyrotoxicosis, unspecified
415.3
266.5
263
7
E05.0
ICD-10 Finland
Thyrotoxicosis with diffuse goitre
885.8
249.4
241
*
104
Kela drug reimbursment
Thyroid insufficiency
6.5
178.3
512
948
E06.0
ICD-10 Finland
Acute thyroiditis
197.8
144.3
149
8
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
4.2
141.6
633
1869
E03.80
ICD-10 Finland
Hypothyroidism caused by autoimmune thyroiditis
13.8
140.0
250
200
2451A
ICD-9 Finland
Thyroiditis, Subacute thyroiditis
+∞
124.0
118
*
H02AB06
ATC
prednisolone; systemic
2.6
112.9
1429
8438
24509
ICD-8 Finland
Thyroiditis, Unspecified
+∞
107.0
102
*
E06.2
ICD-10 Finland
Chronic thyroiditis with transient thyrotoxicosis
+∞
74.3
71
*
24500
ICD-8 Finland
Thyroiditis, Subacuta de Quervain
+∞
74.3
71
*
E06.4
ICD-10 Finland
Drug-induced thyroiditis
+∞
73.3
70
*
EP1AE
NOMESCO Finland
Neck ultrasound examination
4.5
66.3
253
611
E05
ICD-10 Finland
Thyrotoxicosis [hyperthyroidism]
50.7
61.5
74
15
BA1AE
NOMESCO Finland
Thyroiid ultrasound examination
11.1
60.7
118
111
BAA60
NOMESCO Finland
Total thyroidectomy
8.0
60.1
141
185
H06.2*E05.9
ICD-10 Finland
Dysthyroid exophthalmos
+∞
57.5
55
*
2459X
ICD-9 Finland
Thyroiditis, unspecified
+∞
56.5
54
*
C07AA05
ATC
propranolol; systemic
2.3
55.6
628
3179
E03.89
ICD-10 Finland
Other specified hypothyroidism
4.8
52.7
187
417
24503
ICD-8 Finland
Thyroiditis, Chronica
+∞
50.2
48
*
2452A
ICD-9 Finland
Thyroiditis, Chronic lymphocytic thyroiditis
+∞
50.2
48
*
E89.01
ICD-10 Finland
Postsurgical hypothyroidism
8.8
47.5
104
122
24501
ICD-8 Finland
Thyroiditis, Subacuta alia
+∞
47.0
45
*
E03
ICD-10 Finland
Other hypothyroidism
3.3
45.2
249
816
H02AB07
ATC
prednisone; oral
2.4
44.6
450
2129
A02BC02
ATC
pantoprazole; systemic
1.8
39.3
1631
12849
E05.2
ICD-10 Finland
Thyrotoxicosis with toxic multinodular goitre
135.4
37.8
40
*
E05.80
ICD-10 Finland
Subacute thyrotoxicosis
187.6
35.8
37
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
35.7
972
6664
E05.89
ICD-10 Finland
Other thyrotoxicosis
+∞
34.4
33
*
E06
ICD-10 Finland
Thyroiditis
42.6
34.1
42
10
E89.00
ICD-10 Finland
Postirradiation hypothyroidism
32.0
33.5
44
14
H062, E050
ICD-10 Finland
NA
+∞
31.3
30
*
E04.2
ICD-10 Finland
Nontoxic multinodular goitre
3.5
30.9
151
450
C07AB07
ATC
bisoprolol; oral
1.7
30.4
1017
7300
R07.4
ICD-10 Finland
Chest pain, unspecified
1.8
30.1
643
4036
T86
ICPC
Hypothyroidism/myxoedema
3.2
27.4
149
482
C01BD01
ATC
amiodarone; systemic
5.3
26.8
83
160
BA3AT
NOMESCO Finland
Cytology of thyroid with ultrasound quidance
6.3
26.2
71
116
A02BC05
ATC
esomeprazole; systemic
1.6
25.0
993
7334
R53
ICD-10 Finland
Malaise and fatigue
1.8
24.6
526
3273
R07.0
ICD-10 Finland
Pain in throat
2.5
23.9
195
812
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
23.9
941
6917
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
5.0
23.2
76
157
R50.9
ICD-10 Finland
Fever, unspecified
2.0
23.1
345
1891
T85
ICPC
Hyperthyroidism/thyrotoxicosis
17.4
23.1
36
21
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.7
23.1
618
4098
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.6
22.1
790
5642
E03.82
ICD-10 Finland
Hypothyroidism caused by autoimmune thyroiditis
24.4
20.8
29
12
R51.80
ICD-10 Finland
Headache
1.8
20.8
407
2447
H06.2
ICD-10 Finland
Dysthyroid exophthalmos
211.6
20.6
21
*
E06.5
ICD-10 Finland
Other chronic thyroiditis
110.9
20.6
22
*
E04.9
ICD-10 Finland
Nontoxic goitre, unspecified
4.0
20.3
82
209
A02BC03
ATC
lansoprazole; oral
1.6
20.2
685
4806
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
20.2
663
4617
R03AC02
ATC
salbutamol; inhalant
1.5
20.0
1295
10500
E04.1
ICD-10 Finland
Nontoxic single thyroid nodule
4.5
19.9
71
161
BAA40
NOMESCO Finland
Unilateral lobectomy of thyroid gland
3.7
19.4
87
244
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.5
19.2
1084
8513
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
3.1
19.1
109
366
G44.2
ICD-10 Finland
Tension-type headache
1.8
18.8
365
2185
R00.2
ICD-10 Finland
Palpitations
2.2
17.8
198
960
R21
ICPC
Throat symptom/complaint
1.6
17.7
517
3476
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.6
17.7
571
3939
R06.0
ICD-10 Finland
Dyspnoea
1.6
17.5
550
3767
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.6
17.2
566
3918
M54.5
ICD-10 Finland
Low back pain
1.5
16.6
782
5865
N03AX16
ATC
pregabalin; oral
1.6
16.1
550
3831
E03.3
ICD-10 Finland
Postinfectious hypothyroidism
30.2
16.1
21
7
J01FA10
ATC
azithromycin; systemic
1.4
16.1
1442
12222
J01DB01
ATC
cefalexin; oral
1.5
16.0
1977
17840
J01AA02
ATC
doxycycline; systemic
1.5
15.6
1864
16638
24409
ICD-8 Finland
Myxoedema, (hypothyreosis) NUD
13.8
15.5
26
19
M79.6
ICD-10 Finland
Pain in limb
1.4
15.4
841
6476
E04.0
ICD-10 Finland
Nontoxic diffuse goitre
6.6
15.4
39
60
J01DA01
ATC
[U] cefalexin; systemic
1.4
15.2
1493
12803
J01FA06
ATC
roxithromycin; oral
1.4
15.1
957
7576
M79.1
ICD-10 Finland
Myalgia
1.7
14.5
323
2009
P01AB01
ATC
metronidazole; oral, rectal
1.4
14.5
978
7817
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.6
14.3
405
2683
E03.8
ICD-10 Finland
Other specified hypothyroidism
11.4
14.3
26
23
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.6
14.2
408
2716
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.7
14.0
291
1771
M54.4
ICD-10 Finland
Lumbago with sciatica
1.6
13.8
388
2566
R52.9
ICD-10 Finland
Pain, unspecified
1.9
13.8
198
1066
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.2
13.7
138
639
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.7
13.6
271
1630
UJF32
NOMESCO Finland
Coloscopy
1.5
13.5
545
3924
N02AX02
ATC
tramadol; systemic, rectal
1.4
13.4
910
7252
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.6
13.2
392
2630
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
3.8
13.2
55
147
N02BE01
ATC
paracetamol; systemic, rectal
1.5
13.1
2062
18977
K30
ICD-10 Finland
Functional dyspepsia
1.8
13.0
253
1508
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
13.0
492
3489
TFP46
NOMESCO Finland
Ablation treatment of atrial fibrillation
5.1
12.9
40
80
D44.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Thyroid gland
3.9
12.8
52
136
R01AD09
ATC
mometasone; nasal
1.4
12.8
1085
8961
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.6
12.5
373
2503
H04.10
ICD-10 Finland
Dry eye syndrome
1.7
12.3
239
1424
J01MA02
ATC
ciprofloxacin; systemic
1.4
12.1
813
6433
J02AC01
ATC
fluconazole; systemic
1.4
11.9
1069
8872
R51
ICD-10 Finland
Headache
2.1
11.7
131
640
A02BC01
ATC
omeprazole; systemic
1.4
11.7
604
4555
2448A
ICD-9 Finland
Acquired hypothyroidism, Other specified acquired hypothyroidism[HYPOTHYREOSIS POST THYREOIDITIDEM]
30.2
11.6
15
5
E03.2
ICD-10 Finland
Hypothyroidism due to medicaments and other exogenous substances
12.6
11.6
20
16
A03
ICPC
Fever
1.6
11.6
367
2492
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.6
11.4
314
2060
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
11.3
388
2685
M25.5
ICD-10 Finland
Pain in joint
1.4
11.3
665
5132
A06AC01
ATC
ispaghula (psylla seeds); oral
1.4
11.3
532
3938
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
2.8
11.2
70
252
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.5
11.2
354
2406
N01
ICPC
Headache
1.7
11.1
245
1516
207
Kela drug reimbursment
Chronic arrhythmias
1.7
11.0
229
1392
SPAT1263
SPAT
Sampling
1.3
10.8
962
7936
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.6
10.8
327
2197
TFP20
NOMESCO Finland
Cardiodefibrillation
2.1
10.7
117
565
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.3
10.5
911
7478
E05.1
ICD-10 Finland
Thyrotoxicosis with toxic single thyroid nodule
+∞
10.4
10
*
C07AB02
ATC
metoprolol; systemic
1.5
10.4
377
2640
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.6
10.3
301
2007
Z71.8
ICD-10 Finland
Other specified counselling
1.4
10.1
528
3975
BA1AE
SPAT
NA
4.8
10.1
32
67
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.5
10.0
358
2498
R06AX27
ATC
desloratadine; oral
1.4
10.0
652
5099
N03AX12
ATC
gabapentin; oral
1.5
10.0
342
2362
L02
ICPC
Back symptom/complaint
1.7
10.0
213
1306
R13
ICD-10 Finland
Dysphagia
1.9
10.0
136
721
R03DC03
ATC
montelukast; oral
1.5
10.0
382
2707
J03.9
ICD-10 Finland
Acute tonsillitis, unspecified
2.0
9.9
119
600
XX7CT
NOMESCO Finland
Radioiodine therapy of thydoid tissue
6.3
9.8
25
40
M03BX02
ATC
tizanidine; oral
1.3
9.7
1449
12812
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.4
9.7
469
3483
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.7
9.6
208
1279
M03BC01
ATC
orphenadrine (citrate); systemic
1.4
9.5
538
4103
XQ800
NOMESCO Finland
Prick test
1.7
9.5
187
1119
L01
ICPC
Neck symptom/complaint
1.5
9.4
318
2189
A04
ICPC
Weakness/tiredness general
1.6
9.4
276
1840
R74
ICPC
Upper respiratory infection acute
1.4
9.3
665
5276
A10AB04
ATC
insulin lispro; parenteral (insulins and analog. for injection, fast-acting)
2.4
9.3
76
321
N30.0
ICD-10 Finland
Acute cystitis
1.5
9.2
325
2258
R01BA52
ATC
pseudoephedrine, combinations; oral
1.3
9.2
712
5719
SPAT1097
SPAT
Recording of ECG
1.5
9.1
284
1919
J01CA04
ATC
amoxicillin; systemic
1.3
9.1
1930
17855
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
1.7
9.0
177
1059
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
1.4
9.0
479
3610
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
1.9
9.0
139
770
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
2.1
9.0
95
454
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.6
8.9
243
1589
L17
ICPC
Foot/toe symptom/complaint
1.4
8.9
535
4117
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
1.7
8.9
169
1002
TFC25
NOMESCO Finland
Transseptal catheterisation of left atrium or ventricle
4.8
8.8
28
59
XF404
NOMESCO Finland
Ambulatory ECG
1.7
8.8
179
1082
R06AE07
ATC
cetirizine; oral
1.3
8.8
1036
8820
H04AA01
ATC
glucagon; nasal, parenteral
2.7
8.8
58
220
J01
ICD-10 Finland
Acute sinusitis
1.9
8.7
115
604
M53.1
ICD-10 Finland
Cervicobrachial syndrome
1.6
8.7
258
1726
L80
ICD-10 Finland
Vitiligo
7.6
8.6
19
25
E89.09
ICD-10 Finland
Postprocedural hypothyroidism, other or several procedures
11.6
8.6
15
13
A02BA02
ATC
ranitidine; systemic
1.4
8.6
392
2874
M54.2
ICD-10 Finland
Cervicalgia
1.8
8.5
157
919
A03FA02
ATC
cisapride; oral, rectal
1.7
8.5
164
974
E07.9
ICD-10 Finland
Disorder of thyroid, unspecified
10.1
8.5
16
16
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
8.5
1103
9504
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
2.3
8.5
79
356
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.3
8.4
616
4889
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
8.4
1655
15038
TFP35
NOMESCO Finland
Electroanatomical mapping
3.8
8.4
34
91
UDH02
NOMESCO Finland
Rhinopharyngoscopy
1.8
8.4
136
764
I49.1
ICD-10 Finland
Atrial premature depolarization
2.3
8.4
74
327
SHA01
NOMESCO Finland
Correction of physiology of bite - simple therapy visit
1.5
8.4
252
1688
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
2.0
8.3
102
519
2458X
ICD-9 Finland
Thyroiditis, Other and unspecified chronic thyroiditis
+∞
8.3
8
*
XF400
NOMESCO Finland
ECG with 12 standard connections
1.5
8.3
294
2042
K80
ICPC
Cardiac arrhythmia NOS
1.7
8.3
155
914
H05.2
ICD-10 Finland
Exophthalmic conditions
10.8
8.3
15
14
R01AD08
ATC
fluticasone; nasal
1.3
8.3
663
5337
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.6
8.3
209
1344
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.3
8.3
646
5180
R05
ICD-10 Finland
Cough
1.4
8.2
402
2978
SPAT1283
SPAT
Restricted health certificate
1.4
8.2
407
3024
M53.0
ICD-10 Finland
Cervicocranial syndrome
1.6
8.2
197
1250
J01FA09
ATC
clarithromycin; systemic
1.3
8.2
718
5855
N05CF01
ATC
zopiclone; oral
1.3
8.2
674
5447
R42
ICD-10 Finland
Dizziness and giddiness
1.4
8.1
452
3430
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.0
8.1
96
482
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
3.0
8.1
43
143
N02AJ06
ATC
codeine and paracetamol; systemic
1.3
8.0
788
6524
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
8.0
992
8469
C01BC04
ATC
flecainide; systemic
2.4
8.0
65
276
M01AH05
ATC
etoricoxib; oral
1.3
8.0
1322
11711
D11
ICPC
Diarrhoea
1.5
8.0
243
1634
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
1.8
8.0
138
796
H02AB04
ATC
methylprednisolone; systemic
1.5
7.9
310
2203
SPAT1249
SPAT
Treatment-related counselling outside office
1.3
7.8
884
7456
A03FA01
ATC
metoclopramide; systemic, rectal
1.4
7.8
459
3516
J02.9
ICD-10 Finland
Acute pharyngitis, unspecified
1.9
7.8
102
535
R05
ICPC
Cough
1.4
7.7
482
3727
N06AX21
ATC
duloxetine; oral
1.5
7.7
246
1673
E03.0
ICD-10 Finland
Congenital hypothyroidism with diffuse goitre
4.6
7.7
25
55
R94.6
ICD-10 Finland
Abnormal results of thyroid function studies
7.4
7.7
17
23
A02BC04
ATC
rabeprazole; oral
1.6
7.7
193
1238
L16
ICPC
Ankle symptom/complaint
1.6
7.6
216
1428
E10
ICD-10 Finland
Type 1 diabetes mellitus
2.8
7.6
45
160
M03BC51
ATC
orphenadrine, combinations; systemic
1.3
7.6
619
4984
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
1.9
7.5
102
539
R49.01
ICD-10 Finland
Functional dysphonia
2.2
7.5
73
337
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.6
7.5
179
1130
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
2.1
7.5
81
394
UKC02
NOMESCO Finland
Cystoscopy
1.5
7.4
244
1668
H03BA02
ATC
propylthiouracil; oral
80.3
7.4
8
*
N06AX11
ATC
mirtazapine; oral
1.3
7.4
691
5667
XCW99
NOMESCO Finland
Other investigative procedure of eye
1.6
7.4
201
1314
AA1AD
NOMESCO Finland
CT of head and brain
1.4
7.3
429
3279
R03AC03
ATC
terbutaline; inhalant
1.4
7.3
305
2194
24502
ICD-8 Finland
Thyroiditis, Subchronica
+∞
7.3
7
*
2450A
ICD-9 Finland
Thyroiditis, Acute thyroiditis
+∞
7.3
7
*
TFP34
NOMESCO Finland
Electrophysiological investigation
2.4
7.3
58
245
XF402
NOMESCO Finland
ECG with work load test
1.6
7.3
197
1290
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.6
7.3
210
1393
2504
FHL
Unilateral resection or enucleation
4.5
7.3
24
54
R03BA01
ATC
beclometasone; inhalant
1.4
7.2
299
2148
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
1.7
7.2
136
808
D34
ICD-10 Finland
Benign neoplasm of thyroid gland
3.9
7.2
27
69
D10
ICPC
Vomiting
1.7
7.1
129
755
R01AD01
ATC
beclometasone; nasal
1.4
7.1
335
2467
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.5
7.0
255
1780
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.3
7.0
1300
11591
CA1BG
NOMESCO Finland
Eye and orbita MRI examination with high intensity magnet
10.0
7.0
13
13
6481B
ICD-9 Finland
Other current conditions in the mother classifiable elsewhere but complicating pregnancy, childbirth and the puerperium, Thyroid dysfunction[HYPOTHYREOSIS IN GRAVIDITATE]
10.0
7.0
13
13
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.5
7.0
213
1432
C73.91
ICD-10 Finland
Papillary carcinoma of the thyroid gland (thyroid gland)
3.0
7.0
37
124
C07AA07
ATC
sotalol; systemic
2.3
7.0
61
269
SPAT1301
SPAT
No procedures
1.3
7.0
652
5346
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
2.4
6.9
55
230
J45.9
ICD-10 Finland
Asthma, unspecified
1.4
6.9
380
2871
A07AA02
ATC
nystatin; oral
1.7
6.9
132
784
A10AA01
ATC
NA
2.3
6.9
61
271
WYA10
NOMESCO Finland
First aid or other corresponding healthcare contact
1.6
6.9
171
1095
M01AE03
ATC
ketoprofen; systemic, rectal
1.3
6.9
774
6498
A11
ICPC
Chest pain NOS
1.7
6.9
142
866
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.5
6.9
207
1389
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
1.7
6.8
140
852
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
1.8
6.8
104
576
Z01.9
ICD-10 Finland
Special examination, unspecified
1.8
6.8
115
658
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.3
6.8
704
5847
R52.2
ICD-10 Finland
Other chronic pain
2.1
6.8
75
369
XKD00
NOMESCO Finland
Uroflowmetry
1.6
6.8
179
1164
K08.80
ICD-10 Finland
Toothache NOS
1.6
6.7
174
1123
J01MA12
ATC
levofloxacin; systemic
1.4
6.7
346
2584
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.6
6.7
186
1224
M54.6
ICD-10 Finland
Pain in thoracic spine
1.6
6.7
147
912
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.2
6.7
1237
11001
R00.0
ICD-10 Finland
Tachycardia, unspecified
1.9
6.6
89
472
G50.1
ICD-10 Finland
Atypical facial pain
2.5
6.6
47
187
N76.0
ICD-10 Finland
Acute vaginitis
1.7
6.6
143
884
WX110
NOMESCO Finland
Local anesthesy
1.2
6.6
1579
14448
WX408
NOMESCO Finland
General anesthesy, balanced
1.3
6.6
540
4338
ZYC01
NOMESCO Finland
Remote contact by phone
1.9
6.6
95
519
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
1.8
6.6
115
667
K02.1
ICD-10 Finland
Caries of dentine
1.2
6.6
1270
11343
B34.9
ICD-10 Finland
Viral infection, unspecified
2.2
6.5
62
287
M01AB05
ATC
diclofenac; systemic, rectal
1.2
6.5
1505
13704
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.2
6.5
1115
9821
N89
ICPC
Migraine
2.0
6.5
77
389
A01
ICPC
Pain general/multiple sites
1.6
6.4
160
1026
H3600, E103
ICD-10 Finland
NA
3.4
6.4
29
87
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.3
6.4
562
4563
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
2.5
6.4
46
186
B01AA03
ATC
warfarin; systemic
1.4
6.4
282
2054
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
5.2
6.3
18
35
C09CA06
ATC
candesartan; oral
1.3
6.3
429
3357
Z00.0
ICD-10 Finland
General medical examination
1.4
6.3
359
2728
J35.0
ICD-10 Finland
Chronic tonsillitis
1.7
6.3
121
723
24200
ICD-8 Finland
Thyrotoxicosis with or without goitre, Cum struma diffusa et exophthalmo. Morbus Basedowi
+∞
6.3
6
*
24209
ICD-8 Finland
Thyrotoxicosis with or without goitre, Cum struma diffuse NUD
+∞
6.3
6
*
8260/3-C73.9
ICD-O-3
Papillary adenocarcinoma, NOS, of thyroid gland
2.9
6.2
34
117
M02AA07
ATC
piroxicam; topical
1.3
6.2
753
6362
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
1.7
6.2
134
826
M01AE02
ATC
naproxen; oral, rectal
1.2
6.2
1289
11571
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
1.5
6.2
179
1189
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
1.7
6.2
127
771
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.5
6.2
224
1566
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.4
6.1
330
2482
81
HP
Angiography of the heart and coronary arteries
1.9
6.1
79
414
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.5
6.1
175
1161
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.5
6.1
181
1212
ZXE00
NOMESCO Finland
One hour or less
1.2
6.0
850
7307
2506
FHL
Thyroidectomy
10.0
6.0
11
11
SXA20
NOMESCO Finland
Local application of medicine to mouth
1.7
6.0
125
763
M79.7
ICD-10 Finland
Fibromyalgia
1.9
6.0
86
469
Mortality – FinRegistry
↥Association
Association between endpoint THYROIDITIS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| THYROIDITIS | 1.008 [0.89, 1.14] | 0.906 |
| Birth year | 0.996 [0.99, 1.01] | 0.422 |
During the follow-up period (1.1.1998 — 31.12.2019), 612 out of 10163 females with THYROIDITIS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| THYROIDITIS | 0.815 [0.7, 0.94] | 0.007 |
| Birth year | 0.99 [0.98, 1.0] | 0.034 |
During the follow-up period (1.1.1998 — 31.12.2019), 242 out of 2542 males with THYROIDITIS died.
Mortality risk
Mortality risk for people of age
years, who have THYROIDITIS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.087% | 0.169% |
| 5 | 0.579% | 1.044% |
| 10 | 1.518% | 2.768% |
| 15 | 2.872% | 5.227% |
| 20 | 5.1% | 8.575% |
Relationships between endpoints
↥Index endpoint: THYROIDITIS – Thyroiditis
GWS hits: 3
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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