Fibrosis and cirrhosis of liver

K11_FIBROCHIRLIV

cirrhosis of liver: A disorder characterized by replacement of the liver parenchyma with fibrous tissue and regenerative nodules. It is usually caused by alcoholism, hepatitis B, and hepatitis C. Complications include the development of ascites, esophageal varices, bleeding, and hepatic encephalopathy.

Suggest a new description

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 K74
  • Hospital discharge: ICD-9 571[5-6]
  • Hospital discharge: ICD-8 5719
  • Cause of death: ICD-10 K74
  • Cause of death: ICD-9 571[5-6]
  • Cause of death: ICD-8 5719

2 out of 7 registries used, show all original rules.

2738

4. Check minimum number of events

None

2738

5. Include endpoints

None

2738

6. Filter based on genotype QC (FinnGen only)

2738

Control definitions (FinnGen only)

Control exclude
K11_LIVER

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
K70-K77
Name in latin
Fibrosis et cirrhosis hepatis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 23725 11371 11894
Only index persons 16446 8181 8265
Unadjusted period prevalence (%)
Whole population 0.33 0.33 0.33
Only index persons 0.31 0.30 0.32
Median age at first event (years)
Whole population 63.88 64.27 63.53
Only index persons 63.60 63.15 64.04

-FinnGen-

Key figures

All Female Male
Number of individuals 2738 1407 1331
Unadjusted period prevalence (%) 0.53 0.48 0.59
Median age at first event (years) 62.66 60.36 65.09

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2417
Matched controls
24169
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
7.3
323.0
1538
4677
I85.9
ICD-10 Finland
Oesophageal varices without bleeding
536.0
323.0
478
11
A05AA02
ATC
ursodeoxycholic acid; oral
206.5
323.0
704
48
R18
ICD-10 Finland
Ascites
42.7
323.0
462
133
K74.3
ICD-10 Finland
Primary biliary cirrhosis
9896.7
323.0
717
*
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
61.8
323.0
591
126
K70.3
ICD-10 Finland
Alcoholic cirrhosis of liver
1887.4
323.0
454
*
C03DA01
ATC
spironolactone; oral
10.7
323.0
934
1348
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
12.5
323.0
802
921
K74.6
ICD-10 Finland
Other and unspecified cirrhosis of liver
+∞
323.0
1526
*
K76.9
ICD-10 Finland
Liver disease, unspecified
428.2
273.2
269
7
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
6.1
239.3
761
1686
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
6.4
236.9
716
1483
C03CA01
ATC
furosemide; systemic
4.3
233.0
1247
4804
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
59.3
232.7
274
52
K74.0
ICD-10 Finland
Hepatic fibrosis
+∞
207.3
196
*
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
27.5
193.5
270
110
JCA22
NOMESCO Finland
Endoscopic ligature of oesophageal varices
657.4
187.5
183
*
I85.0
ICD-10 Finland
Oesophageal varices with bleeding
1840.8
171.9
165
*
Z94.4
ICD-10 Finland
Liver transplant status
352.6
166.3
166
5
C22.0
ICD-10 Finland
Malignant neoplasm: Liver cell carcinoma
50.9
166.2
201
43
JJ1LE
NOMESCO Finland
Ultrasound elastography of liver
91.0
159.7
177
21
K75.9
ICD-10 Finland
Inflammatory liver disease, unspecified
1607.9
153.8
148
*
JJC00
NOMESCO Finland
Allogenic transplantation of liver
774.7
149.8
146
*
A06AD11
ATC
lactulose; oral
4.1
144.3
681
2130
K73.2
ICD-10 Finland
Chronic active hepatitis, not elsewhere classified
+∞
140.0
133
*
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
3.3
136.3
914
3769
103
Kela drug reimbursment
Diabetes, insulin-treated
3.1
131.4
1001
4492
A10AE04
ATC
insulin glargine; parenteral
4.6
121.6
477
1228
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
12.8
114.3
210
178
K72.9
ICD-10 Finland
Hepatic failure, unspecified
584.8
113.9
112
*
D64.9
ICD-10 Finland
Anaemia, unspecified
4.3
113.1
478
1316
K83.0
ICD-10 Finland
Cholangitis
18.1
109.6
174
103
127
Kela drug reimbursment
Transplant complication
15.2
101.8
173
122
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
4.8
100.7
371
883
K74.5
ICD-10 Finland
Biliary cirrhosis, unspecified
+∞
98.6
94
*
K73.9
ICD-10 Finland
Chronic hepatitis, unspecified
497.2
97.1
96
*
D97
ICPC
Liver disease NOS
51.9
94.8
114
23
A07AA11
ATC
rifaximin; oral
+∞
94.4
90
*
UJF32
NOMESCO Finland
Coloscopy
2.7
93.2
874
4243
215
Kela drug reimbursment
Diabetes, non-insulin-treated
2.7
92.7
843
4015
JJ9AE
NOMESCO Finland
Ultrasound examination of liver transplant
325.1
92.5
93
*
K92.0
ICD-10 Finland
Haematemesis
9.2
91.9
200
234
K72.1
ICD-10 Finland
Chronic hepatic failure
+∞
89.1
85
*
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
57.7
88.9
105
19
A10BA02
ATC
metformin; oral
2.5
84.2
910
4716
A07EA06
ATC
budesonide; oral, local oral
7.5
83.8
208
300
8170/3-C22.0
ICD-O-3
Hepatocellular carcinoma, NOS, of liver
38.2
83.0
106
29
K70.4
ICD-10 Finland
Alcoholic hepatic failure
836.2
83.0
81
*
K76.7
ICD-10 Finland
Hepatorenal syndrome
+∞
81.7
78
*
B18.2
ICD-10 Finland
Chronic viral hepatitis C
22.5
81.7
120
56
T90
ICPC
Diabetes non-insulin dependent
2.6
81.1
781
3781
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
3.6
81.1
408
1278
L04AX01
ATC
azathioprine; systemic
5.8
81.0
244
457
C07AA05
ATC
propranolol; systemic
2.8
80.7
613
2577
N02AX02
ATC
tramadol; systemic, rectal
2.3
80.0
1235
7595
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
11.9
79.8
151
135
L04AA06
ATC
mycophenolic acid; systemic
11.4
78.4
151
140
JA2AT
NOMESCO Finland
Abdominal puncture with ultrasound guidance
19.4
77.8
120
65
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
11.4
77.4
149
138
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.2
76.6
1253
7856
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
4.4
75.9
296
736
K92.1
ICD-10 Finland
Melaena
4.9
74.4
261
581
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
4.0
73.9
328
919
R74.0
ICD-10 Finland
Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]
13.2
73.6
132
105
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
4.0
72.9
322
898
A10BH01
ATC
sitagliptin; oral
3.4
71.5
391
1299
K72.0
ICD-10 Finland
Acute and subacute hepatic failure
687.1
68.3
67
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.2
67.1
974
5667
JJ5AT
NOMESCO Finland
NA
341.3
66.8
67
*
K70.1
ICD-10 Finland
Alcoholic hepatitis
655.3
65.2
64
*
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
17.5
65.2
104
62
TPH04
NOMESCO Finland
Cathetrisation of vein
2.4
63.7
655
3207
K75.4
ICD-10 Finland
Autoimmune hepatitis
+∞
62.8
60
*
D37.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Liver, gallbladder and bile ducts
11.1
62.8
122
115
TJJ00
NOMESCO Finland
Percutaneous needle biopsy of liver
88.8
62.2
69
8
K70.9
ICD-10 Finland
Alcoholic liver disease, unspecified
613.1
61.0
60
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.6
60.3
508
2220
L04AD01
ATC
ciclosporin; systemic
8.2
59.5
137
175
UJF30
NOMESCO Finland
Ileoscopy through colon
3.2
59.2
341
1167
A02BC02
ATC
pantoprazole; systemic
2.1
58.7
1676
12641
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
5.6
58.1
178
338
C07AG02
ATC
carvedilol; oral
3.8
58.0
265
754
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
4.2
58.0
239
620
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
7.4
57.7
142
201
TK800
NOMESCO Finland
Hemodialysis
7.1
57.3
145
214
WW500
NOMESCO Finland
Blood transfusion
5.0
54.5
186
399
A10BB12
ATC
glimepiride; oral
3.4
54.3
285
907
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
9.4
54.2
115
128
K70.0
ICD-10 Finland
Alcoholic fatty liver
58.7
53.7
63
11
A10AE05
ATC
insulin detemir; parenteral
4.0
53.5
230
619
N17.9
ICD-10 Finland
Acute renal failure, unspecified
4.9
52.7
183
400
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
4.8
51.7
182
403
R17
ICD-10 Finland
Hyperbilirubinaemia, with or without jaundice, not elsewhere classified
10.6
51.5
102
100
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.8
50.7
363
1429
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
3.5
50.6
253
773
JN3AD
NOMESCO Finland
Abdominal CT examination
3.3
50.6
285
954
I50.9
ICD-10 Finland
Heart failure, unspecified
2.5
48.0
428
1909
5716A
ICD-9 Finland
Chronic liver disease and cirrhosis, Biliary cirrhosis[CIRRHOSIS BILIARIS PRIMARIA]
+∞
47.0
45
*
A46
ICD-10 Finland
Erysipelas
2.4
46.3
440
2023
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
3.5
46.3
229
693
K73.80
ICD-10 Finland
Non-alcoholic fatty liver (NASH, Non Alcoholic Steatohepatitis)
86.9
46.0
51
6
J01MA02
ATC
ciprofloxacin; systemic
1.9
45.8
1029
6817
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.3
45.3
473
2282
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
8.1
44.4
102
130
ZX120
NOMESCO Finland
Intravenous
2.8
44.1
315
1232
UJK02
NOMESCO Finland
ERCP
5.7
43.5
130
239
R50.9
ICD-10 Finland
Fever, unspecified
2.4
43.2
411
1885
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
2.6
43.0
350
1478
K76.6
ICD-10 Finland
Portal hypertension
+∞
42.8
41
*
TPH07
NOMESCO Finland
Cathetrisation of artery
2.6
42.5
335
1387
JJA20
NOMESCO Finland
Open biopsy of liver
38.7
42.0
53
14
A41.9
ICD-10 Finland
Sepsis, unspecified
4.5
41.8
156
366
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
4.7
41.2
146
325
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.6
41.1
346
1484
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.5
40.7
350
1519
E11
ICD-10 Finland
Type 2 diabetes mellitus
2.2
40.3
470
2375
E66.00
ICD-10 Finland
Metabolic syndrome
3.5
40.1
200
607
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
12.8
40.0
72
58
H02AB06
ATC
prednisolone; systemic
1.8
39.5
1172
8373
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.9
39.2
849
5466
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
5.9
39.0
112
196
WX892
NOMESCO Finland
Monitored bed care
2.9
39.0
259
962
I81
ICD-10 Finland
Portal vein thrombosis
32.5
38.9
51
16
C10AC01
ATC
colestyramine; oral
5.2
38.2
122
243
K29.7
ICD-10 Finland
Gastritis, unspecified
4.2
38.1
153
386
WX408
NOMESCO Finland
General anesthesy, balanced
1.9
38.0
694
4194
K29.6
ICD-10 Finland
Other gastritis
9.8
38.0
78
82
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
3.2
37.8
214
714
K74.2
ICD-10 Finland
Hepatic fibrosis with hepatic sclerosis
+∞
36.5
35
*
JN4CD
NOMESCO Finland
Very extensive body CT
3.9
36.0
157
426
R94.5
ICD-10 Finland
Abnormal results of liver function studies
10.7
35.9
70
67
SPAT1262
SPAT
Handing over of treatment supplies
2.0
35.7
522
2887
57199
ICD-8 Finland
Cirrhosis of liver, Unspecified
+∞
35.5
34
*
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
3.4
35.4
180
554
8000/3-C22.0
ICD-O-3
Neoplasm, malignant of liver
96.5
34.8
38
*
160
Kela drug reimbursment
exenatide
5.6
34.7
104
192
N02AA05
ATC
oxycodone; systemic
2.1
33.5
428
2233
XW000
NOMESCO Finland
Bone marrow biopsy
3.5
33.4
165
497
JL5SB
NOMESCO Finland
Endoscopic retrograd cholangiopancreaticography
6.7
32.7
85
131
R4110
NOMESCO Finland
Physiotherapy
1.8
32.7
689
4338
JJA21
NOMESCO Finland
Laparoscopic biopsy of liver
31.2
32.6
43
14
ZXE40
NOMESCO Finland
More than seven and less than nine hours
4.9
32.5
109
229
E87.5
ICD-10 Finland
Hyperkalaemia
6.1
32.4
91
155
I50.0
ICD-10 Finland
Congestive heart failure
2.7
32.1
229
889
205
Kela drug reimbursment
Chronic hypertension
1.8
31.9
761
4977
UJD02
NOMESCO Finland
Gastroscopy
3.2
31.7
176
578
198
Kela drug reimbursment
Sorafenib
24.9
31.4
44
18
Z2446
NOMESCO Finland
Social worker
3.0
31.3
194
687
WX002
NOMESCO Finland
Sedation and analgesia
1.9
31.1
537
3141
K76.89
ICD-10 Finland
Other specified diseases of liver
316.8
30.9
31
*
M04AA01
ATC
allopurinol; systemic
2.1
30.6
372
1895
R06.0
ICD-10 Finland
Dyspnoea
1.8
30.4
626
3891
57198
ICD-8 Finland
Cirrhosis of liver, Alia definita, alcoholismo non indicato
+∞
30.3
29
*
Z2221
NOMESCO Finland
Medical doctor
1.8
30.1
673
4296
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
2.7
30.0
224
892
I86.4
ICD-10 Finland
Gastric varices
306.1
29.9
30
*
Z51.5
ICD-10 Finland
Palliative care
2.8
29.5
202
763
ZXD05
NOMESCO Finland
Urgent procedure
1.7
29.4
734
4840
JCA32
NOMESCO Finland
Endoscopic injection in oesophagus
50.7
29.4
35
7
XF400
NOMESCO Finland
ECG with 12 standard connections
2.0
29.0
454
2557
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
3.2
28.9
159
519
J01MA12
ATC
levofloxacin; systemic
1.9
28.7
505
2964
177
Kela drug reimbursment
Insulin glargine 300 U / ml
5.3
28.7
89
172
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
3.2
28.6
157
512
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.9
28.6
477
2748
K51.5
ICD-10 Finland
Left sided colitis
4.7
28.5
99
217
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
4.3
28.1
108
262
A10BH05
ATC
linagliptin; oral
3.1
28.0
160
536
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.4
28.0
256
1138
J01FF01
ATC
clindamycin; systemic
1.7
27.9
663
4296
H02AB04
ATC
methylprednisolone; systemic
2.0
27.9
390
2100
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
3.7
27.9
125
348
C22.9
ICD-10 Finland
Malignant neoplasm: Liver, unspecified
15.1
27.8
46
31
G93.4
ICD-10 Finland
Encephalopathy, unspecified
25.7
27.5
38
15
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.8
27.4
563
3480
WX872
NOMESCO Finland
Intensive care
3.0
27.4
164
568
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
3.8
27.4
121
333
57309
ICD-8 Finland
Other diseases of liver, Unspecified
+∞
27.1
26
*
PC2DT
NOMESCO Finland
Embolisation of lesion of liver
62.8
27.0
31
5
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.9
26.4
420
2372
EBA15
NOMESCO Finland
Extraction of large number of teeth
3.3
26.4
137
429
K29.3
ICD-10 Finland
Chronic superficial gastritis
3.7
26.3
120
339
K74.4
ICD-10 Finland
Secondary biliary cirrhosis
+∞
26.1
25
*
K73.0
ICD-10 Finland
Chronic persistent hepatitis, not elsewhere classified
+∞
26.1
25
*
ZXE00
NOMESCO Finland
One hour or less
1.6
25.7
912
6582
JN4BD
NOMESCO Finland
Extensive body CT
2.1
25.6
314
1598
C07AB07
ATC
bisoprolol; oral
1.6
25.5
1164
8953
K83.8
ICD-10 Finland
Other specified diseases of biliary tract
28.7
25.4
34
12
Z3226
NOMESCO Finland
Physiotherapist
1.8
25.1
466
2772
K70.2
ICD-10 Finland
Alcoholic fibrosis and sclerosis of liver
+∞
25.0
24
*
K83.9
ICD-10 Finland
Disease of biliary tract, unspecified
18.4
24.8
38
21
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
3.8
24.7
106
285
E66.01
ICD-10 Finland
Obesity due to excess calories
2.6
24.6
196
806
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.3
24.4
127
399
TJA10
NOMESCO Finland
Laparocentesis
18.8
24.3
37
20
E11.4
ICD-10 Finland
Type 2 diabetes mellitus, with neurological complications
4.2
24.3
94
230
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.7
24.2
587
3798
A10BG03
ATC
pioglitazone; oral
3.9
24.0
100
262
Z3231
NOMESCO Finland
Registered nurse
1.7
23.8
669
4514
PC2DE
NOMESCO Finland
Ultrasound examination of liver vasculature with Doppler method
242.3
23.7
24
*
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.8
23.4
159
598
E11.6
ICD-10 Finland
Type 2 diabetes mellitus, with other specified complications
4.4
22.9
84
195
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
2.9
22.8
142
505
A10AD05
ATC
insulin aspart; parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)
4.6
22.8
80
178
N19
ICD-10 Finland
Unspecified kidney failure
3.4
22.7
112
338
R04.0
ICD-10 Finland
Epistaxis
2.4
22.4
206
915
A28
ICPC
Limited function/disability NOS
1.9
22.3
386
2233
A10BJ02
ATC
liraglutide; parenteral
4.0
22.3
90
229
R60.0
ICD-10 Finland
Localized oedema
2.0
22.3
294
1537
JJ3AT
NOMESCO Finland
Cytology of liver with ultrasound guidance
35.4
22.1
28
8
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
3.0
21.9
131
453
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.9
21.9
358
2028
K74.1
ICD-10 Finland
Hepatic sclerosis
+∞
21.9
21
*
UJF92
NOMESCO Finland
Capsular endoscopy
4.7
21.9
75
163
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.9
21.8
140
507
K29.5
ICD-10 Finland
Chronic gastritis, unspecified
3.4
21.7
108
328
L01XE05
ATC
[U] sorafenib; oral
22.4
21.7
31
14
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
4.0
21.6
87
221
JCA20
NOMESCO Finland
Ligature of oesophageal varices
221.9
21.6
22
*
P15
ICPC
Chronic alcohol abuse
4.1
21.6
86
217
N17.8
ICD-10 Finland
Other acute renal failure
7.0
21.5
53
77
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.9
21.3
321
1764
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
3.1
21.1
117
385
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.8
20.8
372
2176
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
2.9
20.8
131
470
F10.25
ICD-10 Finland
Alcohol dependence continuous use
5.1
20.6
65
129
E66.9
ICD-10 Finland
Obesity, unspecified
3.6
20.6
95
272
A10BX07
ATC
[U] liraglutide; parenteral
5.4
20.6
62
117
JN1BG
NOMESCO Finland
MRI examination of upper part of abodmen with high intensity magnet
7.0
20.2
50
73
162
Kela drug reimbursment
liraglutide
6.1
20.1
55
92
A10BD07
ATC
metformin and sitagliptin; systemic
2.7
20.1
142
546
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
20.0
503
3265
A07EC02
ATC
mesalazine; oral, rectal
2.6
19.9
149
593
K83.1
ICD-10 Finland
Obstruction of bile duct
5.4
19.8
60
114
5761C
ICD-9 Finland
Other disorders of biliary tract, Cholangitis[CHOLANGITIS SCLEROSIVA]
+∞
19.8
19
*
I85
ICD-10 Finland
Oesophageal varices
+∞
19.8
19
*
K74
ICD-10 Finland
Fibrosis and cirrhosis of liver
+∞
19.8
19
*
JX1XE
NOMESCO Finland
Other ultrasound examinaton of alimentary organs
74.1
19.7
22
*
JL5CG
NOMESCO Finland
Extensive MRI examinaiton of bile and pancreas ducts with high intesity magnet
7.4
19.5
46
63
JN1CD
NOMESCO Finland
Very extensive CT examination of upper part of abdomen
8.2
19.4
43
53
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
3.8
19.4
83
224
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
3.1
19.1
109
365
A10BX04
ATC
[U] exenatide; parenteral
6.1
19.1
52
87
F10.20
ICD-10 Finland
Alcohol dependence currently independent
4.5
19.0
68
155
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.6
19.0
671
4753
B18.1
ICD-10 Finland
Chronic viral hepatitis B without delta-agent
34.6
18.9
24
7
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
3.3
18.9
95
292
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.0
18.9
244
1263
I35.0
ICD-10 Finland
Aortic (valve) stenosis
2.4
18.8
166
723
JJ6LT
NOMESCO Finland
Coagulation of focal hepatic lesion under ultrasound guidance
28.0
18.7
25
9
S97
ICPC
Chronic ulcer skin
2.5
18.6
150
621
WX882
NOMESCO Finland
High dependency care
3.5
18.6
88
258
AA1AD
NOMESCO Finland
CT of head and brain
1.6
18.4
558
3798
K42.9
ICD-10 Finland
Umbilical hernia without obstruction or gangrene
2.6
18.3
135
531
E0000UV
ATC
NA
1.5
18.2
846
6371
J01DB01
ATC
cefalexin; oral
1.5
18.2
1847
16384
JN4AD
NOMESCO Finland
Body CT examination
2.1
18.2
211
1042
I10
ICD-10 Finland
Essential (primary) hypertension
1.5
18.2
1380
11512
E66.8
ICD-10 Finland
Other obesity
2.7
18.2
125
475
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.9
18.1
277
1529
A10BK03
ATC
empagliflozin; oral
2.2
17.9
186
873
JKD20
NOMESCO Finland
Anastomosis of bile duct to jejunum
67.1
17.7
20
*
D73.1
ICD-10 Finland
Hypersplenism
67.1
17.7
20
*
UJK12
NOMESCO Finland
Peroral cholangioscopy
14.7
17.6
29
20
A12BA01
ATC
potassium chloride; oral
2.6
17.5
130
514
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
2.5
17.4
144
606
E000001
ATC
NA
1.7
17.4
435
2804
R41.0
ICD-10 Finland
Disorientation, unspecified
3.2
17.3
93
301
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.3
17.2
164
742
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.5
17.2
731
5386
XF600
NOMESCO Finland
Bloodpressure measurement
2.3
17.1
166
756
ZXD10
NOMESCO Finland
Scheduled procedure
1.5
17.1
866
6619
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.5
17.0
869
6653
N18.8
ICD-10 Finland
Other chronic renal failure
3.1
16.9
94
311
N05CD07
ATC
temazepam; oral
1.8
16.9
322
1912
N05CF01
ATC
zopiclone; oral
1.5
16.9
740
5479
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
2.4
16.8
145
622
L04AA01
ATC
[U] ciclosporin; systemic
4.3
16.8
63
151
TKC20
NOMESCO Finland
Catheterisation of bladder
2.1
16.8
190
930
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.6
16.7
589
4149
5719X
ICD-9 Finland
Chronic liver disease and cirrhosis, Unspecified chronic liver disease without mention of alcohol
+∞
16.7
16
*
E11.3
ICD-10 Finland
Type 2 diabetes mellitus, with ophthalmic complications
3.0
16.6
95
320
D69.3
ICD-10 Finland
Idiopathic thrombocytopenic purpura
7.7
16.6
38
50
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
3.2
16.6
87
277
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
3.7
16.5
73
203
V03AE01
ATC
polystyrene sulfonate; oral
5.2
16.5
51
100
A41.8
ICD-10 Finland
Other specified sepsis
4.2
16.5
63
154
A10BB01
ATC
glibenclamide; oral
2.6
16.5
124
494
RS120
NOMESCO Finland
NA
23.2
16.4
23
10
RS220
NOMESCO Finland
NA
5.2
16.2
50
98
M10.9
ICD-10 Finland
Gout, unspecified
2.2
16.2
168
792
R02
ICPC
Shortness of breath/dyspnoea
1.8
16.1
284
1645
R53
ICD-10 Finland
Malaise and fatigue
1.6
16.0
450
2992
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
3.2
15.9
85
274
K80.5
ICD-10 Finland
Calculus of bile duct without cholangitis or cholecystitis
3.3
15.9
80
247
E13.9
ICD-10 Finland
Other specified diabetes mellitus, without complications
6.1
15.9
43
72
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.8
15.8
290
1702
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.5
15.8
671
4924
6611
FHL
Needle biopsy in the operating room
60.4
15.8
18
*
R60.9
ICD-10 Finland
Oedema, unspecified
2.5
15.7
126
520
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.7
15.7
344
2132
E87.6
ICD-10 Finland
Hypokalaemia
3.1
15.7
87
288
ZXE20
NOMESCO Finland
More than three and less than five hours
1.7
15.7
337
2078
R56.8
ICD-10 Finland
Other and unspecified convulsions
2.6
15.6
119
478
5715A
ICD-9 Finland
Chronic liver disease and cirrhosis, Cirrhosis of liver without mention of alcohol
+∞
15.6
15
*
E88.0
ICD-10 Finland
Disorders of plasma-protein metabolism, not elsewhere classified
22.2
15.5
22
10
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
2.9
15.5
96
342
ZXE30
NOMESCO Finland
More than five and less than seven hours
2.3
15.5
140
619
A10AB04
ATC
insulin lispro; parenteral (insulins and analog. for injection, fast-acting)
3.0
15.4
91
315
T36
ICD-10 Finland
Poisoning by systemic antibiotics
2.8
15.4
101
374
R93.2
ICD-10 Finland
Abnormal findings on diagnostic imaging of liver and biliary tract
7.7
15.4
35
46
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
2.7
15.3
103
386
XCK10
NOMESCO Finland
Photography of fundus of eye
1.9
15.3
253
1434
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
3.6
15.2
68
192
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
4.3
15.2
56
133
I50
ICD-10 Finland
Heart failure
2.9
15.1
93
330
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.7
15.1
309
1873
A10AB06
ATC
insulin glulisine; parenteral
5.5
15.1
44
81
L28
ICPC
Limited function/disability (L)
1.7
15.1
373
2392
A08
ICPC
Swelling
2.6
15.0
113
454
K42.0
ICD-10 Finland
Umbilical hernia with obstruction, without gangrene
5.6
14.9
43
78
PC2ET
NOMESCO Finland
Extensive embolisation of lesion of liver
31.9
14.8
19
6
WVA20
NOMESCO Finland
Medicine administration
3.6
14.8
67
191
K25.9
ICD-10 Finland
Gastric ulcer, Unspecified as acute or chronic, without haemorrhage or perforation
4.0
14.8
59
151
ZX108
NOMESCO Finland
Inhalation
7.2
14.8
35
49
L04AA05
ATC
[U] tacrolimus; systemic
21.2
14.6
21
10
D07AC01
ATC
betamethasone; topical
1.5
14.6
741
5620
K76.1
ICD-10 Finland
Chronic passive congestion of liver
+∞
14.6
14
*
5714X
ICD-9 Finland
Chronic liver disease and cirrhosis, Chronic hepatitis[HEPATITIS CHRONICA ALIA SEU NUD]
+∞
14.6
14
*
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
3.2
14.5
77
248
N05BA04
ATC
oxazepam; oral
1.5
14.4
527
3725
JAH00
NOMESCO Finland
Laparotomy
3.0
14.4
82
276
L40.0
ICD-10 Finland
Psoriasis vulgaris
2.5
14.4
112
458
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
4.2
14.3
54
131
JKE32
NOMESCO Finland
Endoscopic dilatation of bile duct
11.4
14.3
26
23
3A422
NOMESCO Finland
NA
42.7
14.1
17
*
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
1.8
14.0
244
1405
F10.31
ICD-10 Finland
Withdrawal symptoms caused by alcohol with seizures
7.3
14.0
33
46
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.1
13.9
158
774
M34.1
ICD-10 Finland
CR(E)ST syndrome
7.8
13.8
31
40
B01AA03
ATC
warfarin; systemic
1.5
13.7
459
3175
D64.8
ICD-10 Finland
Other specified anaemias
4.0
13.7
54
137
JAH01
NOMESCO Finland
Laparoscopy
2.5
13.7
107
437
K50.8
ICD-10 Finland
Other Crohn disease
4.2
13.7
51
123
K80.3
ICD-10 Finland
Calculus of bile duct with cholangitis
6.4
13.7
35
55
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
5.3
13.6
41
79
JJC60
NOMESCO Finland
Total excision of transplanted liver
+∞
13.6
13
*
A10BJ06
ATC
semaglutide; parenteral
2.8
13.5
88
324
C09AA02
ATC
enalapril; systemic
1.5
13.5
466
3246
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
11.0
13.5
25
23
SPAT1255
SPAT
Intravenous administration of medicine
2.0
13.4
164
831
K51.1
ICD-10 Finland
Ulcerative (chronic) ileocolitis
6.0
13.3
36
61
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.5
13.3
517
3696
F10.24
ICD-10 Finland
Alcohol depence active use
4.3
13.2
48
113
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.2
13.2
135
634
3AC01
NOMESCO Finland
NA
4.8
13.1
43
91
323
Kela drug reimbursment
Sorafenib
40.3
13.1
16
*
M05BA04
ATC
alendronic acid; oral
1.9
13.1
205
1140
B80
ICPC
Iron deficiency anaemia
3.7
13.0
56
154
JKE02
NOMESCO Finland
Transduodenal endoscopic incision of common bile duct orifice
3.9
13.0
53
139
JFA98
NOMESCO Finland
Other transluminal endoscopic local operation on intestine
3.4
13.0
63
191
K65.0
ICD-10 Finland
Acute peritonitis
4.7
12.9
43
93
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
2.8
12.9
84
310
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.5
12.8
446
3105
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
1.8
12.8
226
1306
C01AA05
ATC
digoxin; systemic
1.9
12.8
195
1074
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
4.6
12.7
43
95
F11.25
ICD-10 Finland
Relationship caused by opiates continuously used
15.5
12.6
20
13
S42.2
ICD-10 Finland
Fracture of upper end of humerus
2.4
12.6
110
480
E14.9
ICD-10 Finland
Unspecified diabetes mellitus, without complications
3.6
12.5
56
159
R4190
NOMESCO Finland
Nutritional therapy
2.7
12.5
87
335
K75.3
ICD-10 Finland
Granulomatous hepatitis, not elsewhere classified
+∞
12.5
12
*
A02BC01
ATC
omeprazole; systemic
1.4
12.5
611
4577
B01AB05
ATC
enoxaparin; parenteral
1.4
12.4
678
5190
A10BK01
ATC
dapagliflozin; oral
2.3
12.3
111
491
SPAT1265
SPAT
Breathalyser
6.0
12.2
33
56
B82
ICPC
Anaemia other/unspecified
2.9
12.2
72
251
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
3.0
12.2
71
245
D62
ICD-10 Finland
Acute posthaemorrhagic anaemia
5.0
12.2
38
77
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.0
12.1
154
790
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
3.8
12.1
51
138
K26.9
ICD-10 Finland
Duodenal ulcer, unspecified as acute or chronic, without haemorrhage or perforation
5.1
12.1
37
73
A10BJ05
ATC
dulaglutide; parenteral
6.1
12.1
32
53
K51.0
ICD-10 Finland
Ulcerative (chronic) pancolitis
6.1
12.1
32
53
JN1BD
NOMESCO Finland
Extensive CT examination of upper part of abdomen
5.4
12.1
35
65
ZXE10
NOMESCO Finland
More than one and less than three hours
1.4
12.0
785
6194
F19.1
ICD-10 Finland
Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances, harmful use
11.1
12.0
22
20
TJA40
NOMESCO Finland
Percutaneous local drainage of peritoneal cavity
46.9
11.9
14
*
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.3
11.8
107
473
T89
ICPC
Diabetes insulin dependent
2.6
11.8
86
340
F11.22
ICD-10 Finland
Addiction-induced dependence is currently independent but uses substitute intermittent medication
11.8
11.8
21
18
E66.0
ICD-10 Finland
Obesity due to excess calories
4.6
11.7
40
89
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.0
11.7
157
823
K51.8
ICD-10 Finland
Other ulcerative colitis
4.3
11.6
42
99
N06AX11
ATC
mirtazapine; oral
1.4
11.6
657
5045
J94.8
ICD-10 Finland
Other specified pleural conditions
3.5
11.6
53
154
3A064
NOMESCO Finland
NA
11.1
11.5
21
19
C08CA01
ATC
amlodipine; oral
1.4
11.5
818
6539
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.2
11.5
115
534
K76.4
ICD-10 Finland
Peliosis hepatis
+∞
11.5
11
*
K71.9
ICD-10 Finland
Toxic liver disease, unspecified
+∞
11.5
11
*
K73.89
ICD-10 Finland
Other long-term hepatitis, not classified differently
+∞
11.5
11
*
K75.8
ICD-10 Finland
Other specified inflammatory liver diseases
+∞
11.5
11
*
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
11.4
372
2546
JJA44
NOMESCO Finland
Laparoscopic destruction of lesion of liver
120.6
11.4
12
*
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.7
11.4
244
1499
F19.29
ICD-10 Finland
Addiction caused by several drugs in combination and by other psychoactive substances UNS
15.1
11.3
18
12
N30.0
ICD-10 Finland
Acute cystitis
1.6
11.3
287
1847
F15.1
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, harmful use
35.2
11.3
14
*
JDA52
NOMESCO Finland
Other endoscopic procedure using diathermy or heat in stomach or pylorus
10.6
11.3
21
20
D69.5
ICD-10 Finland
Secondary thrombocytopenia
10.6
11.3
21
20
JDA32
NOMESCO Finland
Endoscopic injection in stomach or pylorus
9.6
11.2
22
23
UJF02
NOMESCO Finland
Peroral enteroscopy
6.2
11.2
29
47
K29.0
ICD-10 Finland
Acute haemorrhagic gastritis
5.7
11.2
31
55
K86.00
ICD-10 Finland
Acute pancreatitis caused by alcohol
3.9
11.2
44
113
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
2.1
11.1
127
628
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.2
11.0
110
511
201
Kela drug reimbursment
Chronic cardiac insufficiency
2.1
11.0
119
570
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.7
11.0
237
1458
N05BA01
ATC
diazepam; systemic, rectal
1.6
11.0
287
1860
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
2.2
11.0
109
503
2500A
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE,TYYPPI II]
3.0
11.0
63
215
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
3.1
11.0
60
200
K31.8
ICD-10 Finland
Other specified diseases of stomach and duodenum
6.9
10.8
26
38
A10BH02
ATC
vildagliptin; oral
3.0
10.8
62
211
C09AA05
ATC
ramipril; oral
1.4
10.8
558
4206
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
1.9
10.8
164
903
K86.1
ICD-10 Finland
Other chronic pancreatitis
4.9
10.8
34
70
K65.9
ICD-10 Finland
Peritonitis, unspecified
10.6
10.8
20
19
JDA42
NOMESCO Finland
Other endoscopic haemostatic procedure in stomach or pylorus
8.9
10.8
22
25
K25.7
ICD-10 Finland
Gastric ulcer, Chronic without haemorrhage or perforation
4.2
10.7
39
93
E78.0
ICD-10 Finland
Pure hypercholesterolaemia
0.6
10.7
187
2934
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
4.7
10.7
35
75
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
2.7
10.7
72
273
N06AX16
ATC
venlafaxine; oral
1.6
10.7
255
1615
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
1.9
10.7
151
810
K85.9
ICD-10 Finland
Acute pancreatitis, unspecified
3.3
10.7
53
165
E83.1
ICD-10 Finland
Disorders of iron metabolism
6.7
10.7
26
39
K55.2
ICD-10 Finland
Angiodysplasia of colon
6.7
10.7
26
39
K07
ICPC
Swollen ankles/oedema
2.2
10.6
107
499
SPAT1254
SPAT
Administration of medicine
1.6
10.6
320
2150
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.6
10.6
260
1657
A41.1
ICD-10 Finland
Sepsis due to other specified staphylococcus
6.0
10.6
28
47
JN3KE
NOMESCO Finland
Abdominal ultrasound with added contrast
6.0
10.6
28
47
R60.1
ICD-10 Finland
Generalized oedema
7.0
10.6
25
36
TGC00
NOMESCO Finland
Bronchial lavation
2.7
10.5
71
270
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
1.9
10.5
159
875
TK810
NOMESCO Finland
Hemofiltration
6.2
10.4
27
44
H02AB09
ATC
hydrocortisone; systemic
3.1
10.4
55
179
K75.0
ICD-10 Finland
Abscess of liver
+∞
10.4
10
*
I98.2
ICD-10 Finland
Oesophageal varices without bleeding in diseases classified elsewhere
+∞
10.4
10
*
5714B
ICD-9 Finland
Chronic liver disease and cirrhosis, Chronic hepatitis[HEPATITIS CHRONICA ACTIVA (HBSAG-)]
+∞
10.4
10
*
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.7
10.4
228
1408
D13.1
ICD-10 Finland
Benign neoplasm: Stomach
2.9
10.4
61
213
R16.1
ICD-10 Finland
Splenomegaly, not elsewhere classified
12.1
10.3
18
15
JJ7LT
NOMESCO Finland
Coagulation of focal hepatic lesion under CT guidance
32.7
10.3
13
*
C02EA02
ATC
NA
2.1
10.3
114
554
Z72.1
ICD-10 Finland
Alcohol use
4.4
10.3
36
83
XX1AT
NOMESCO Finland
Other puncture with ultrasound guidance
4.3
10.3
37
88
Z94.9
ICD-10 Finland
Transplanted organ and tissue status, unspecified
18.9
10.3
15
8
1300
FHL
Esophagogastroduodenoscopy (also includes staining)
4.8
10.2
33
70
D25
ICPC
Abdominal distension
3.3
10.2
50
154
F10.41
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol with seizures
23.5
10.2
14
6
N07BB01
ATC
disulfiram; oral
2.3
10.2
94
421
J45.9
ICD-10 Finland
Asthma, unspecified
1.5
10.2
368
2576
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
1.7
10.2
226
1398
B03XA02
ATC
darbepoetin alfa; parenteral
3.1
10.2
55
182
K50.9
ICD-10 Finland
Crohn disease, unspecified
3.6
10.2
44
123
JKE22
NOMESCO Finland
Endoscopic extraction of foreign body from bile duct
7.5
10.2
23
31
A40.8
ICD-10 Finland
Other streptococcal sepsis
4.7
10.1
33
71
Z94.0
ICD-10 Finland
Kidney transplant status
3.9
10.1
40
104
H3600, E113
ICD-10 Finland
NA
3.7
10.1
42
114
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.0
10.1
134
702
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.8
10.0
181
1056
JAF10
NOMESCO Finland
Repair of umbilical hernia
2.8
10.0
61
219
RD210
NOMESCO Finland
NA
3.2
10.0
50
157
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
2.1
10.0
112
549
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
1.7
10.0
206
1252
L04AA10
ATC
sirolimus; oral
40.2
10.0
12
*
B99
ICD-10 Finland
Other and unspecified infectious diseases
3.1
10.0
53
174
E000006
ATC
NA
1.9
9.9
149
816
F19.25
ICD-10 Finland
Addiction caused by several drugs in combination and by other psychoactive substances continuously used
16.8
9.9
15
9
G62.1
ICD-10 Finland
Alcoholic polyneuropathy
12.2
9.8
17
14
D50.8
ICD-10 Finland
Other iron deficiency anaemias
3.6
9.8
43
122
5739X
ICD-9 Finland
Other disorders of liver, Unspecified disorder of liver
20.1
9.8
14
7
D05AX52
ATC
calcipotriol, combinations; topical
2.0
9.8
126
653
JF1CG
NOMESCO Finland
Extensive MRI of small bowel
7.0
9.8
23
33
K05.31
ICD-10 Finland
Periodontitis pronounced
1.7
9.8
217
1344
R03AC02
ATC
salbutamol; inhalant
1.3
9.8
1079
9171
WX402
NOMESCO Finland
General anaesthesia
1.5
9.7
340
2360
WX419
NOMESCO Finland
Other general anesthesy
4.0
9.7
37
93
A07AA09
ATC
vancomycin; oral
3.9
9.7
38
98
I36.1
ICD-10 Finland
Nonrheumatic tricuspid (valve) insufficiency
3.8
9.7
39
103
D12.3
ICD-10 Finland
Benign neoplasm: Transverse colon
2.7
9.7
63
236
N06AB04
ATC
citalopram; systemic
1.4
9.7
432
3159
JKE18
NOMESCO Finland
Endoscopic internal drainage of bile duct
4.2
9.7
35
84
EBA10
NOMESCO Finland
Surgical removal of tooth
1.7
9.6
189
1129
K02.2
ICD-10 Finland
Caries of cementum
2.1
9.6
105
510
N05AH04
ATC
quetiapine; oral
1.5
9.6
297
2006
A10AD01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)
3.1
9.6
51
168
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.4
9.4
656
5192
K75.2
ICD-10 Finland
Nonspecific reactive hepatitis
100.4
9.4
10
*
2BB01
NOMESCO Finland
NA
100.4
9.4
10
*
5718X
ICD-9 Finland
Chronic liver disease and cirrhosis, Other chronic nonalcoholic liver disease
+∞
9.4
9
*
57300
ICD-8 Finland
Other diseases of liver, Hepatitis NUD
+∞
9.4
9
*
C22
ICD-10 Finland
Malignant neoplasm of liver and intrahepatic bile ducts
+∞
9.4
9
*
K73.8
ICD-10 Finland
Other chronic hepatitis, not elsewhere classified
+∞
9.4
9
*
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.8
9.4
168
977
K65.8
ICD-10 Finland
Other peritonitis
12.4
9.4
16
13
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
2.5
9.3
68
272
F10.09
ICD-10 Finland
Alcohol intoxication UNS
3.1
9.3
50
166
R11
ICD-10 Finland
Nausea and vomiting
1.8
9.3
162
934
F10.39
ICD-10 Finland
Withdrawal symptoms caused by alcohol UNS
4.3
9.3
33
78
I83.0
ICD-10 Finland
Varicose veins of lower extremities with ulcer
2.7
9.3
60
224
Z72.2
ICD-10 Finland
Drug use
9.5
9.3
18
19
K08.3
ICD-10 Finland
Retained dental root
1.8
9.2
149
838
K50.1
ICD-10 Finland
Crohn disease of large intestine
4.1
9.2
34
83
A11CC03
ATC
alfacalcidol; systemic
2.6
9.2
66
259
E11.1
ICD-10 Finland
Type 2 diabetes mellitus, with ketoacidosis
6.0
9.2
24
40
JKA20
NOMESCO Finland
Cholecystectomy
2.5
9.2
70
286
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.9
9.2
137
749
G03FA14
ATC
dydrogesterone and estrogen; systemic (progestogens and estrogens, fixed comb.)
0.3
9.1
23
690
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
3.1
9.1
47
152
F05.9
ICD-10 Finland
Delirium, unspecified
3.0
9.1
52
178
JN3CG
NOMESCO Finland
Extensive MRI examination of abdomen with high intensity magnet
6.3
9.1
23
37
D12.2
ICD-10 Finland
Benign neoplasm: Ascending colon
2.4
9.0
76
328
A10BX02
ATC
repaglinide; oral
3.5
9.0
40
115
H02AB07
ATC
prednisone; oral
1.5
9.0
311
2154
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.7
9.0
197
1217
K26.0
ICD-10 Finland
Duodenal ulcer, acute with haemorrhage
4.9
9.0
28
58
K80.8
ICD-10 Finland
Other cholelithiasis
3.1
9.0
46
148
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
1.7
9.0
203
1267
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
3.4
9.0
41
121
TPX10
NOMESCO Finland
Implantation of vascular injection port
2.4
8.9
72
304
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.5
8.9
363
2602
N03AX16
ATC
pregabalin; oral
1.4
8.9
499
3805
F13.20
ICD-10 Finland
Addiction relationship caused by sedatives and hypnotics currently independent
12.6
8.9
15
12
C03AA03
ATC
hydrochlorothiazide; oral
1.6
8.8
214
1360
C07AB02
ATC
metoprolol; systemic
1.4
8.8
454
3406
F10.2
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Dependence syndrome
4.3
8.8
31
73
O99.6
ICD-10 Finland
Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
10.7
8.8
16
15
L03.1
ICD-10 Finland
Cellulitis of other parts of limb
2.6
8.8
60
231
E87.2
ICD-10 Finland
Acidosis
6.3
8.8
22
35
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
5.6
8.7
24
43
K55.8
ICD-10 Finland
Other vascular disorders of intestine
5.6
8.7
24
43
G63.2*E11.4
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic polyneuropathy
3.6
8.7
37
103
M01AB01
ATC
indometacin; systemic, rectal
1.7
8.7
184
1124
A10BD03
ATC
metformin and rosiglitazone; systemic
3.0
8.7
47
157
R73.9
ICD-10 Finland
Hyperglycaemia, unspecified
2.6
8.7
60
233
E86
ICD-10 Finland
Volume depletion
2.6
8.7
60
233
JKE25
NOMESCO Finland
Endoscopic external drainage of bile duct
14.1
8.7
14
10
A02BD07
ATC
lansoprazole, amoxicillin and clarithromycin; systemic
2.0
8.7
109
561
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
1.7
8.7
172
1033
D07AD01
ATC
clobetasol; topical
1.5
8.6
316
2216
P01AB01
ATC
metronidazole; oral, rectal
1.3
8.6
804
6633
3018X
ICD-9 Finland
Personality disorders, Other personality disorders[MUU TAI SEKAMUOTOINEN PERSOONALLISUUSHÄIRIÖ]
5.0
8.6
26
52
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.4
8.6
379
2758
F11.29
ICD-10 Finland
Addiction caused by opiates UNS
16.3
8.5
13
8
JAF30
NOMESCO Finland
Repair of umbilical hernia using prosthetic material
2.8
8.5
54
198
XF612
NOMESCO Finland
Measurement of central venous pressure
9.0
8.5
17
19
F19.20
ICD-10 Finland
Addiction relationship caused by several drugs in combination and by other psychoactive substances currently independent
10.1
8.5
16
16
K02.9
ICD-10 Finland
Dental caries, unspecified
3.3
8.5
40
121
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.5
8.5
343
2452
L02.2
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of trunk
2.2
8.5
82
376
B17.1
ICD-10 Finland
Acute hepatitis C
20.1
8.5
12
6
R03BB04
ATC
tiotropium bromide; inhalant
1.6
8.4
224
1456
A98
ICPC
Health maint/preventive medicine
0.7
8.4
1996
21027
SPAT1088
SPAT
Blood transfusion
5.7
8.4
23
41
F10.40
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without seizures
3.8
8.4
34
91
K70
ICD-10 Finland
Alcoholic liver disease
90.4
8.4
9
*
B01AB10
ATC
tinzaparin; parenteral
1.8
8.4
147
848
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.5
8.4
324
2294
ZZA00
NOMESCO Finland
Split skin graft
2.3
8.4
74
327
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
3.0
8.4
45
150
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
3.4
8.4
38
112
D02AE01
ATC
carbamide; topical
1.8
8.4
136
768
RS122
NOMESCO Finland
NA
12.8
8.4
14
11
319
Kela drug reimbursment
Adalimumab, brodalumab, certolizumab pegol, etanercept, guselkumab, infliximab, ixekizumab, risankizumab, sekukinumab and ustekinumab (skin psoriasis)
6.7
8.4
20
30
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.4
8.4
464
3524
A07AA02
ATC
nystatin; oral
1.8
8.3
145
838
JCA35
NOMESCO Finland
Endoscopic contact coagulation in oesophagus
+∞
8.3
8
*
R16.2
ICD-10 Finland
Hepatomegaly with splenomegaly, not elsewhere classified
+∞
8.3
8
*
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
2.3
8.3
76
342
M10.0
ICD-10 Finland
Idiopathic gout
2.3
8.3
74
330
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
2.4
8.3
68
291
Z94.1
ICD-10 Finland
Heart transplant status
10.8
8.3
15
14
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
9.5
8.3
16
17
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
1.7
8.2
175
1074
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.4
8.2
465
3543
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
2.7
8.2
53
198
A10BJ01
ATC
exenatide; parenteral
4.2
8.2
29
69
SPAT1309
SPAT
Guidance related to psychoactive substances / risk behaviour
2.7
8.2
54
206
J01DA01
ATC
[U] cefalexin; systemic
1.3
8.1
1329
11795
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
2.1
8.1
87
419
S18
ICPC
Laceration/cut
1.3
8.1
905
7637
Z49.1
ICD-10 Finland
Extracorporeal dialysis
3.0
8.1
44
148
M81.9
ICD-10 Finland
Osteoporosis, unspecified
2.1
8.1
89
432
D23
ICPC
Hepatomegaly
33.5
8.1
10
*
JN1CM
NOMESCO Finland
Upper part of abdomen extensive MRI examination with 3 Tesla magnet
17.2
8.1
12
7
F15.2
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, dependence syndrome
11.7
8.1
14
12
A40.1
ICD-10 Finland
Sepsis due to streptococcus, group B
11.7
8.1
14
12
S76
ICPC
Skin infection other
1.9
8.1
108
568
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
1.8
8.0
133
754
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
2.1
8.0
93
462
A10AE06
ATC
insulin degludec; parenteral
2.5
8.0
62
255
C08CA02
ATC
felodipine; oral
1.6
8.0
206
1329
K81.9
ICD-10 Finland
Cholecystitis, unspecified
3.8
8.0
32
85
F41.09
ICD-10 Finland
UNS Panic Syndrome
2.8
8.0
48
172
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
1.6
8.0
212
1379
UJD10
SPAT
NA
3.4
8.0
37
111
3039X
ICD-9 Finland
Alcohol dependence syndrome, Other and unspecified alcohol dependence
3.1
8.0
41
133
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
1.8
8.0
127
713
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
3.1
8.0
42
139
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
1.8
7.9
134
768
A10BB07
ATC
glipizide; oral
3.1
7.9
41
134
EBA00
NOMESCO Finland
Extraction of tooth
1.3
7.9
638
5143
JDA22
NOMESCO Finland
Endoscopic ligature of varices of stomach
13.1
7.9
13
10
Z71.4
ICD-10 Finland
Alcohol abuse counselling and surveillance
7.8
7.9
17
22
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.3
7.9
1014
8714
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.3
7.8
610
4890
SPAT1263
SPAT
Sampling
1.3
7.8
869
7320
A04
ICPC
Weakness/tiredness general
1.5
7.8
241
1625
Z3229
NOMESCO Finland
Other healthcare associate professional
1.6
7.8
188
1191
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.4
7.8
351
2563
4019X
ICD-9 Finland
Essential hypertension, Unspecified
2.3
7.8
67
294
A63.0
ICD-10 Finland
Anogenital (venereal) warts
2.7
7.8
50
187
K86.2
ICD-10 Finland
Cyst of pancreas
4.0
7.8
29
73
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
1.8
7.7
127
722
R77.0
ICD-10 Finland
Abnormality of albumin
15.1
7.7
12
8
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.4
7.7
338
2457
ZXE60
NOMESCO Finland
More than 12 and less than 15 hours
4.6
7.7
25
55
JDA05
NOMESCO Finland
Endoscopic polypectomy in stomach or pylorus
5.6
7.7
21
38
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
3.8
7.6
30
79
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.4
7.6
375
2786
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
1.7
7.6
154
933
L29.9
ICD-10 Finland
Pruritus, unspecified
2.5
7.6
57
233
A10BX01
ATC
guar gum; systemic
2.1
7.6
84
413
K76.80
ICD-10 Finland
Hepatic cyst
18.4
7.6
11
6
D12.4
ICD-10 Finland
Benign neoplasm: Descending colon
2.9
7.6
42
144
3049X
ICD-9 Finland
Drug dependence, Unspecified drug dependence
25.1
7.6
10
*
474
NOMESCO Finland
NA
25.1
7.6
10
*
WX110
NOMESCO Finland
Local anesthesy
1.3
7.6
1409
12660
Z02.7
ICD-10 Finland
Issue of medical certificate
1.8
7.5
125
712
N17.0
ICD-10 Finland
Acute renal failure with tubular necrosis
5.8
7.5
20
35
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.3
7.5
503
3940
H3601, E113
ICD-10 Finland
NA
2.9
7.5
43
149
A10BG02
ATC
rosiglitazone; oral
3.0
7.5
41
140
A02BC03
ATC
lansoprazole; oral
1.3
7.5
613
4947
JL5AM
NOMESCO Finland
Bile and pancreas ducts simple MRI examination with 3 Tesla magnet
80.3
7.4
8
*
4560A
ICD-9 Finland
Varicose veins of other sites, Oesophageal varices with bleeding
80.3
7.4
8
*
H26.3
ICD-10 Finland
Drug-induced cataract
5.0
7.4
22
44
Y57
ICD-10 Finland
Adverse effects in the therapeutic use of other and unspecified drugs and medicaments
2.8
7.4
45
164
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
1.9
7.4
107
583
F11.24
ICD-10 Finland
Addiction-induced dependence caused by opiates active addiction
13.4
7.4
12
9
176
Kela drug reimbursment
Regorafenib
13.4
7.4
12
9
K80.0
ICD-10 Finland
Calculus of gallbladder with acute cholecystitis
2.0
7.4
93
482
DKW00
NOMESCO Finland
Cauterisation of mucosa of nose
3.6
7.4
31
87
K25.3
ICD-10 Finland
Gastric ulcer, Acute without haemorrhage or perforation
3.9
7.4
28
72
S29
ICPC
Skin symptom/complaint other
1.4
7.3
336
2461
B03BA03
ATC
hydroxocobalamin; parenteral
1.8
7.3
127
733
XG410
NOMESCO Finland
Flow-volume spirometry
2.0
7.3
90
460
E000003
ATC
NA
2.0
7.3
90
460
L01BB02
ATC
mercaptopurine; oral
4.3
7.3
25
58
NEA10
NOMESCO Finland
Exploration of soft tissue of pelvis, percutaneous
8.4
7.3
15
18
UGC12
NOMESCO Finland
Flexible bronchoscopy
1.6
7.3
169
1063
57308
ICD-8 Finland
Other diseases of liver, Alii definiti
+∞
7.3
7
*
K71.2
ICD-10 Finland
Toxic liver disease with acute hepatitis
+∞
7.3
7
*
6615
FHL
Liver transplant
+∞
7.3
7
*
K76.5
ICD-10 Finland
Hepatic veno-occlusive disease
+∞
7.3
7
*
ZXE90
NOMESCO Finland
More than 22 hours
4.2
7.3
26
63
A02BC05
ATC
esomeprazole; systemic
1.3
7.3
848
7175
XQ841
NOMESCO Finland
Examination of dermatosis with microscope
9.4
7.3
14
15
F13.22
ICD-10 Finland
Addiction relationship caused by sedatives and hypnotics currently independent but uses substitute intermittent medication
9.4
7.3
14
15
K22.6
ICD-10 Finland
Gastro-oesophageal laceration-haemorrhage syndrome
4.9
7.3
22
45
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
1.9
7.3
100
535
WVA40
NOMESCO Finland
Initiation and monitoring of intravenous hydration
3.2
7.2
36
115
I50.1
ICD-10 Finland
Left ventricular failure
1.9
7.2
102
551
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.5
7.2
282
2000
602
Kela drug reimbursment
Children's severe malnutrition
15.8
7.2
11
7
A09AA02
ATC
multienzymes (lipase, protease etc.)
2.6
7.2
48
185
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
1.8
7.2
122
699
E16.2
ICD-10 Finland
Hypoglycaemia, unspecified
3.4
7.2
32
94
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
1.6
7.2
203
1341
Z13.1
ICD-10 Finland
Special screening examination for diabetes mellitus
3.3
7.2
34
105
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
3.1
7.2
36
116
F60.9
ICD-10 Finland
Personality disorder, unspecified
3.9
7.2
27
69
XPX08
NOMESCO Finland
Intraoperative flow measurement
3.7
7.2
29
79
RS321
NOMESCO Finland
NA
20.1
7.1
10
5
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
2.2
7.1
71
335
N40
ICD-10 Finland
Hyperplasia of prostate
0.7
7.1
253
3462
E13.8
ICD-10 Finland
Other specified diabetes mellitus, with unspecified complications
12.1
7.1
12
10
J01AA02
ATC
doxycycline; systemic
1.3
7.1
1722
15922
JKE12
NOMESCO Finland
Endoscopic extraction of calculus from bile duct
3.6
7.1
30
85
K86.08
ICD-10 Finland
Alcohol-induced chronic pancreatitis
6.0
7.1
18
30
R79.9
ICD-10 Finland
Abnormal finding of blood chemistry, unspecified
6.0
7.1
18
30
K85
ICD-10 Finland
Acute pancreatitis
2.6
7.1
47
181
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
1.9
7.1
106
584
I33.0
ICD-10 Finland
Acute and subacute infective endocarditis
4.7
7.0
22
47
C03EB01
ATC
furosemide and potassium-sparing agents; systemic
1.9
7.0
94
499
XF622
NOMESCO Finland
Measurement of minute volume of heart
7.0
7.0
16
23
F10.26
ICD-10 Finland
Alcohol dependence periodic alcoholism
3.0
7.0
37
124
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.5
7.0
244
1695
A03
ICPC
Fever
1.5
6.9
255
1787
2BD01
NOMESCO Finland
NA
7.5
6.9
15
20
D61.9
ICD-10 Finland
Aplastic anaemia, unspecified
13.8
6.9
11
8
D07AC13
ATC
mometasone; topical
1.3
6.9
580
4690
L76
ICPC
Fracture: other
2.3
6.9
61
273
SBB00
NOMESCO Finland
Fotograf of mouth and teeth
2.1
6.8
73
353
DKW30
NOMESCO Finland
Cauterisation of artery of internal nose
4.8
6.8
21
44
M34.9
ICD-10 Finland
Systemic sclerosis, unspecified
6.7
6.8
16
24
S91.3
ICD-10 Finland
Open wound of other parts of foot
2.5
6.8
51
208
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
1.9
6.8
88
460
R06AE07
ATC
cetirizine; oral
1.3
6.8
834
7088
M81.4
ICD-10 Finland
Drug-induced osteoporosis
6.1
6.8
17
28
3044A
ICD-9 Finland
Drug dependence, Amphetamine and other psychostimulant dependence
40.2
6.8
8
*
3019
Kela drug reimbursment
Lenvatinib
40.2
6.8
8
*
L01EX02
ATC
sorafenib; oral
40.2
6.8
8
*
L17
ICPC
Foot/toe symptom/complaint
1.3
6.7
501
3978
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
1.8
6.7
113
648
QDG20
NOMESCO Finland
Operation for chronic ulcer or fistula of skin of lower limb
3.4
6.7
30
89
N05AA02
ATC
levomepromazine; systemic
2.0
6.7
83
429
S32.0
ICD-10 Finland
Fracture of lumbar vertebra
2.2
6.6
65
305
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
3.1
6.6
34
112
D12.0
ICD-10 Finland
Benign neoplasm: Caecum
2.4
6.6
53
224
ZY010
NOMESCO Finland
Hospital outpatient
2.0
6.6
78
393
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
2.2
6.6
65
306
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.6
6.6
160
1017
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
6.6
718
6002
N05CF02
ATC
zolpidem; oral
1.4
6.6
335
2501
K25.4
ICD-10 Finland
Gastric ulcer, Chronic or unspecified with haemorrhage
3.9
6.6
25
65
130
Kela drug reimbursment
Malignant tumour
1.6
6.6
172
1116
F60.2
ICD-10 Finland
Dissocial personality disorder
8.7
6.5
13
15
SPAT1225
SPAT
Implementation of podiatry rehabilitation plan
2.1
6.5
66
312
B81
ICPC
Anaemia vit B12/folate deficiency
1.9
6.5
86
453
K86.01
ICD-10 Finland
Late effects of pancreatitis caused by alcohol
10.0
6.5
12
12
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.4
6.5
322
2391
E11.5
ICD-10 Finland
Type 2 diabetes mellitus, with peripheral circulatory complications
2.5
6.5
49
200
K80
ICD-10 Finland
Cholelithiasis
3.2
6.5
31
97
SPAT1216
SPAT
Assessment of functional ability
1.4
6.5
324
2411
K31.7
ICD-10 Finland
Polyp of stomach and duodenum
5.7
6.4
17
30
H36.00
ICD-10 Finland
Diabetic background retinopathy
2.9
6.4
35
120
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.6
6.4
163
1048
5761A
ICD-9 Finland
Other disorders of biliary tract, Cholangitis[CHOLANGITIS SUPPURATIVA]
70.0
6.4
7
*
0705A
ICD-9 Finland
Viral hepatitis, Other specified viral hepatitis without mention of hepatic coma
70.0
6.4
7
*
SPAT1281
SPAT
Other administrative function
1.6
6.4
155
986
A40.9
ICD-10 Finland
Streptococcal sepsis, unspecified
7.4
6.4
14
19
XX4BW
NOMESCO Finland
NA
7.4
6.4
14
19
S20
ICPC
Corn/callosity
2.4
6.4
49
204
ZJX00
NOMESCO Finland
Double balloon technique in gastroenterological endoscopy
14.3
6.4
10
7
F10.9
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Unspecified mental and behavioural disorder
3.6
6.4
26
72
K02.1
ICD-10 Finland
Caries of dentine
1.2
6.4
1087
9585
N02AC04
ATC
dextropropoxyphene; oral
1.9
6.3
85
453
N05AB01
ATC
dixyrazine; systemic
3.0
6.3
34
116
C07AB03
ATC
atenolol; systemic
1.7
6.3
128
776
5BA08
NOMESCO Finland
NA
5.2
6.3
18
35
G31.2
ICD-10 Finland
Degeneration of nervous system due to alcohol
4.2
6.3
22
53
D63.8
ICD-10 Finland
Anaemia in other chronic diseases classified elsewhere
6.0
6.3
16
27
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
1.7
6.3
116
686
GD1AD
NOMESCO Finland
Thorax CT examination
1.8
6.3
96
536
WXQ27
NOMESCO Finland
UVB narrow spectrum light therapy
3.3
6.3
29
89
5710A
ICD-9 Finland
Chronic liver disease and cirrhosis, Alcoholic fatty liver
+∞
6.3
6
*
57100
ICD-8 Finland
Cirrhosis of liver, Cirrhosis cum alcoholismo
+∞
6.3
6
*
TJA00
NOMESCO Finland
Puncture of peritoneum
26.7
6.2
8
*
I78.8
ICD-10 Finland
Other diseases of capillaries
7.0
6.2
14
20
H03AA01
ATC
levothyroxine sodium; systemic
1.3
6.2
457
3620
RS221
NOMESCO Finland
NA
2.7
6.2
38
141
F10.21
ICD-10 Finland
Alcohol dependence currently abstinent, but staying in restrictive environment
3.5
6.2
26
74
I73.0
ICD-10 Finland
Raynaud syndrome
2.8
6.2
36
128
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
2.8
6.2
36
128
318
Kela drug reimbursment
Teriparatide
5.0
6.2
18
36
P01BA02
ATC
hydroxychloroquine; oral
1.6
6.2
165
1079
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
1.9
6.2
91
500
SPC35
NOMESCO Finland
Production and attachment of single tooth bridge
2.8
6.2
37
135
N06AX03
ATC
mianserin; oral
1.8
6.2
97
547
9694A
ICD-9 Finland
Poisoning by psychotropic agents, Benzodiazepine-based tranquillisers
4.5
6.2
20
45
H05AA02
ATC
teriparatide; parenteral
5.3
6.1
17
32
X59
ICD-10 Finland
Exposure to unspecified factor
1.4
6.1
345
2620
H36.01
ICD-10 Finland
Diabetic maculopathy
2.9
6.1
33
113
310
Kela drug reimbursment
Orlistat, sibutramine and other major and expensive medicines used to treat obesity
2.9
6.1
33
113
TQW11
NOMESCO Finland
Vacuum treatment of wound
2.5
6.1
45
185
N05BA12
ATC
alprazolam; oral
1.5
6.1
198
1352
A03FA01
ATC
metoclopramide; systemic, rectal
1.3
6.1
408
3187
J01CF05
ATC
flucloxacillin; systemic
1.9
6.1
79
417
K51
ICD-10 Finland
Ulcerative colitis
4.0
6.1
22
55
1280
FHL
Endoscopic retrograde cholangiography and pancreaticography
12.5
6.1
10
8
K77
ICPC
Heart failure
2.4
6.0
47
198
P19
ICPC
Drug abuse
4.9
6.0
18
37
K29.2
ICD-10 Finland
Alcoholic gastritis
6.7
6.0
14
21
D07XC01
ATC
betamethasone, combinations; topical
1.5
6.0
231
1634
R19.8
ICD-10 Finland
Other specified symptoms and signs involving the digestive system and abdomen
3.0
6.0
32
109

Mortality – FinRegistry

Association

Association between endpoint K11_FIBROCHIRLIV and mortality.

Females

Parameter HR [95% CI] p-value
K11_FIBROCHIRLIV 4.932 [4.37, 5.57] < 0.001
Birth year 0.991 [0.98, 1.0] 0.028

During the follow-up period (1.1.1998 — 31.12.2019), 2888 out of 6837 females with K11_FIBROCHIRLIV died.

Males

Parameter HR [95% CI] p-value
K11_FIBROCHIRLIV 7.217 [6.12, 8.51] < 0.001
Birth year 0.985 [0.98, 0.99] 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 3915 out of 6725 males with K11_FIBROCHIRLIV died.

Mortality risk

Mortality risk for people of age

years, who have K11_FIBROCHIRLIV.

N-year risk Females Males
1 0.42% 1.153%
5 2.374% 6.99%
10 6.022% 16.152%
15 11.499% 29.88%
20 19.055% 47.457%

Relationships between endpoints

Index endpoint: K11_FIBROCHIRLIV – Fibrosis and cirrhosis of liver

GWS hits: 3

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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