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Procedures for purposes other than remedying health state

Z21_PROCED_PURPO_OTH_REMED_HEALTH_STATE

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 Z41
  • Cause of death: ICD-10 Z41

2 out of 7 registries used, show all original rules.

958

4. Check minimum number of events

None

958

5. Include endpoints

None

958

6. Filter based on genotype QC (FinnGen only)

958

Control definitions (FinnGen only)

Control exclude
Z21_PERSONS_ENCOUNTERI_HEALTH_SERVI_SPECIFIC_PROCED_HEALTH_CARE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
Z4|Z5[0-4]

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 958 823 135
Unadjusted period prevalence (%) 0.25 0.28 0.06
Median age at first event (years) 49.03 49.23 47.80

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
848
Matched controls
8480
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Z41.1
ICD-10 Finland
Other plastic surgery for unacceptable cosmetic appearance
16384.0
323.0
651
*
QAJ30
NOMESCO Finland
Other facelift
295.3
126.8
126
5
HAD10
NOMESCO Finland
Augmentation of breast using prosthesis
146.0
109.1
114
9
Z41.8
ICD-10 Finland
Other procedures for purposes other than remedying health state
+∞
84.8
80
*
QAJ99
NOMESCO Finland
Other aesthetic operations on skin of head or neck
+∞
81.6
77
*
QBJ00
NOMESCO Finland
Liposuction in trunk
73.5
81.3
92
14
Z41.9
ICD-10 Finland
Procedure for purposes other than remedying health state, unspecified
+∞
74.0
70
*
CBB20
NOMESCO Finland
Correction of lax skin of eyelid and resection of herniated fat
28.7
64.5
88
34
Z41
ICD-10 Finland
Procedures for purposes other than remedying health state
+∞
31.4
30
*
QAJ00
NOMESCO Finland
Liposuction in head or neck
+∞
30.4
29
*
QBJ30
NOMESCO Finland
Correction of abdominal apron
19.3
29.0
44
24
H02.3
ICD-10 Finland
Blepharochalasis
3.9
22.1
97
274
N05CF02
ATC
zolpidem; oral
2.5
21.9
209
995
V500A
ICD-9 Finland
Elective surgery for purposes other than remedying health states, Hair transplant
39.8
21.8
27
7
N05CF01
ATC
zopiclone; oral
2.2
21.5
297
1689
CBD00
NOMESCO Finland
Plastic reconstruction of eyelid using suture
61.6
21.0
24
*
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
13.5
20.3
35
27
J01MA02
ATC
ciprofloxacin; systemic
2.0
19.5
329
2015
N06AX11
ATC
mirtazapine; oral
2.1
19.3
302
1792
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.0
19.0
390
2568
Z41.2
ICD-10 Finland
Routine and ritual circumcision
+∞
18.8
18
*
DLD20
NOMESCO Finland
Rhinoplasty
45.0
18.3
22
5
N05BA12
ATC
alprazolam; oral
2.8
18.1
126
495
HAD40
NOMESCO Finland
Mastopexy
17.0
17.9
28
17
Z41.0
ICD-10 Finland
Hair transplant
+∞
17.8
17
*
Z2221
NOMESCO Finland
Medical doctor
2.0
17.3
270
1583
Z46.1
ICD-10 Finland
Fitting and adjustment of hearing aid
+∞
16.7
16
*
J02AC01
ATC
fluconazole; systemic
1.8
16.2
436
3097
HAD50
NOMESCO Finland
Removal of prosthetic implant from breast
21.4
16.0
23
11
N06AB04
ATC
citalopram; systemic
2.1
16.0
216
1190
J05AB11
ATC
valaciclovir; oral
2.4
15.9
149
691
Z42.1
ICD-10 Finland
Follow-up care involving plastic surgery of breast
86.7
15.6
17
*
Z50.1
ICD-10 Finland
Other physical therapy
11.6
14.8
27
24
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
1.9
14.8
289
1821
N06AB10
ATC
escitalopram; oral
2.1
14.8
201
1105
QDJ00
NOMESCO Finland
Liposuction in lower extremity
81.5
14.6
16
*
ZXD10
NOMESCO Finland
Scheduled procedure
1.8
14.4
344
2319
9862
FHL
Facial skin shaping surgery (Faclift)
43.2
14.1
17
*
ZZF00
NOMESCO Finland
Graft of adipose tissue
11.7
13.8
25
22
J01AA07
ATC
tetracycline; systemic
2.2
13.7
165
856
N06AX16
ATC
venlafaxine; oral
2.2
13.7
147
727
D10BA01
ATC
isotretinoin; oral
3.1
13.6
78
272
L90.5
ICD-10 Finland
Scar conditions and fibrosis of skin
9.6
13.5
27
29
R4110
NOMESCO Finland
Physiotherapy
1.9
13.4
219
1289
N05AH04
ATC
quetiapine; oral
2.2
13.3
151
766
HAD30
NOMESCO Finland
Reduction mammoplasty with transposition of areola
3.6
13.2
60
176
N05BA04
ATC
oxazepam; oral
1.9
13.1
222
1322
QAJ15
NOMESCO Finland
Browlift using video-endoscope
70.9
12.6
14
*
N06AB03
ATC
fluoxetine; oral
2.2
12.5
134
659
J01DB01
ATC
cefalexin; oral
1.9
12.4
690
5924
HAD99
NOMESCO Finland
Other plastic operation on breast
16.1
12.2
19
12
C07AA05
ATC
propranolol; systemic
2.0
12.1
186
1063
N62
ICD-10 Finland
Hypertrophy of breast
3.2
11.8
61
198
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
16.7
11.7
18
11
T85.4
ICD-10 Finland
Mechanical complication of breast prosthesis and implant
23.2
11.6
16
7
Z3226
NOMESCO Finland
Physiotherapist
2.0
11.3
154
841
Z22.3
ICD-10 Finland
Carrier of other specified bacterial diseases
25.4
11.2
15
6
DAD30
NOMESCO Finland
Plastic repair of auricle
43.9
10.9
13
*
N02AX02
ATC
tramadol; systemic, rectal
1.7
10.7
324
2291
CBD99
NOMESCO Finland
Other plastic reconstruction of eyelid
60.8
10.6
12
*
QBJ05
NOMESCO Finland
Other correction of loose or redundant skin of trunk
+∞
10.4
10
*
QAJ10
NOMESCO Finland
Browlift
23.7
10.3
14
6
N06AB06
ATC
sertraline; oral
2.2
10.3
109
535
HAD00
NOMESCO Finland
Augmentation mammoplasty
40.5
10.0
12
*
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.6
9.6
373
2794
J01MA06
ATC
norfloxacin; oral
2.0
9.6
136
751
N05BA01
ATC
diazepam; systemic, rectal
2.1
9.6
119
625
Z3231
NOMESCO Finland
Registered nurse
1.8
9.5
199
1253
E0000UV
ATC
NA
1.6
9.2
319
2314
O04.9
ICD-10 Finland
Medical abortion, complete or unspecified, without complication
2.3
9.2
85
390
ZXE10
NOMESCO Finland
More than one and less than three hours
1.6
9.1
291
2066
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
9.0
216
1417
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.1
8.9
106
545
Z2445
NOMESCO Finland
Psychologist
3.5
8.6
39
116
L57.4
ICD-10 Finland
Cutis laxa senilis
27.8
8.5
11
*
Z53.2
ICD-10 Finland
Procedure not carried out because of patient's decision for other and unspecified reasons
20.2
8.5
12
6
N06AB05
ATC
paroxetine; oral
2.4
8.5
68
292
EBA00
NOMESCO Finland
Extraction of tooth
0.6
8.4
114
1845
QXJ05
NOMESCO Finland
Excision of lax skin for cosmetic reasons, unspecified location
90.9
8.4
9
*
QAF00
NOMESCO Finland
Hair bearing graft of skin to scalp
90.9
8.4
9
*
J01DA01
ATC
[U] cefalexin; systemic
1.5
8.4
519
4288
M03AX01
ATC
botulinum toxin; parenteral
6.3
8.3
21
34
Z49.1
ICD-10 Finland
Extracorporeal dialysis
+∞
8.3
8
*
XX9AW
NOMESCO Finland
Production of copy from X-ray picture
3.4
8.3
38
114
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.7
8.2
176
1113
ZXA10
NOMESCO Finland
Bilateral
1.8
8.2
146
871
Z76
ICD-10 Finland
Persons encountering health services in other circumstances
5.2
8.2
24
47
QAE20
NOMESCO Finland
Excision and repair of scar or web of skin of head or neck
11.8
8.1
14
12
H04.10
ICD-10 Finland
Dry eye syndrome
2.1
8.0
96
496
ZXE00
NOMESCO Finland
One hour or less
1.5
7.9
318
2373
S01GX01
ATC
cromoglicic acid; ophthalmic
1.7
7.9
186
1209
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.6
7.8
54
213
M01AE01
ATC
ibuprofen; systemic, rectal
1.9
7.8
766
7049
Z51.5
ICD-10 Finland
Palliative care
9.5
7.8
15
16
QAJ20
NOMESCO Finland
Subperiosteal facelift
80.7
7.4
8
*
QBJ99
NOMESCO Finland
Other aesthetic correction of skin of trunk
80.7
7.4
8
*
T90
ICPC
Diabetes non-insulin dependent
0.5
7.4
49
980
A06AC01
ATC
ispaghula (psylla seeds); oral
1.6
7.4
201
1355
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.5
7.3
447
3638
J01AA04
ATC
lymecycline; systemic
1.8
7.3
121
703
J01FF01
ATC
clindamycin; systemic
1.6
7.2
208
1424
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.5
7.2
264
1914
G03DC05
ATC
[U] tibolone; oral
2.5
7.2
56
234
N95.1
ICD-10 Finland
Menopausal and female climacteric states
1.9
7.2
112
635
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
2.1
7.2
79
393
J05AB01
ATC
aciclovir; systemic
1.6
7.2
188
1252
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.6
7.2
191
1282
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
30.3
7.2
9
*
J01FA10
ATC
azithromycin; systemic
1.5
7.1
499
4164
QBE20
NOMESCO Finland
Excision and repair of scar or web of skin of trunk
8.9
7.1
14
16
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.0
7.0
88
462
UJF30
NOMESCO Finland
Ileoscopy through colon
2.1
6.9
74
364
N06AA12
ATC
doxepin; systemic
2.6
6.9
48
192
C01CA24
ATC
epinephrine; parenteral
2.4
6.8
57
250
N03AX16
ATC
pregabalin; oral
1.6
6.8
183
1226
TK800
NOMESCO Finland
Hemodialysis
11.0
6.8
12
11
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
6.8
285
2129
G03FA12
ATC
medroxyprogesterone and estrogen; systemic (progestogens and estrogens, fixed comb.)
2.2
6.8
67
320
D10AX03
ATC
azelaic acid; topical
2.1
6.7
76
384
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
6.7
288
2162
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
6.7
196
1346
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.5
6.7
417
3381
X59
ICD-10 Finland
Exposure to unspecified factor
1.7
6.6
132
815
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.9
6.6
91
498
M01AH05
ATC
etoricoxib; oral
1.4
6.5
482
4035
J01MA12
ATC
levofloxacin; systemic
1.7
6.5
125
764
R06AE07
ATC
cetirizine; oral
1.5
6.5
368
2924
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.1
6.5
72
363
QAJ35
NOMESCO Finland
Other correction of loose or redundant skin of head or neck
70.3
6.4
7
*
P01AB01
ATC
metronidazole; oral, rectal
1.5
6.4
346
2720
QDJ05
NOMESCO Finland
Correction of loose or redundant skin of lower extremity
+∞
6.3
6
*
D06BX01
ATC
metronidazole; topical
1.8
6.2
104
605
QAE40
NOMESCO Finland
Repair of anomaly or lesion after disease of skin of head or neck
26.9
6.2
8
*
Y5099
ICD-8 Finland
Plastic surgery for cosmetic reasons
26.9
6.2
8
*
HAE99
NOMESCO Finland
Other reconstruction of breast
6.3
6.2
15
24
ZXE20
NOMESCO Finland
More than three and less than five hours
1.9
6.2
86
473
J02AB02
ATC
ketoconazole; oral
3.1
6.2
31
102
Z3229
NOMESCO Finland
Other healthcare associate professional
2.3
6.1
53
240
HAE20
NOMESCO Finland
Reconstruction of areola and mamilla using graft or flap
4.4
6.1
20
46
G03FB05
ATC
norethisterone and estrogen; systemic (progestogens and estrogens, sequential prep.)
1.7
6.0
119
731
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
4.2
6.0
21
51

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: Z21_PROCED_PURPO_OTH_REMED_HEALTH_STATE – Procedures for purposes other than remedying health state

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).