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Bitten or stung by nonvenomous insect and other nonvenomous arthropods

VWXY20_BITTEN_STUNG_NONVENO_INSECT_OTHER_NONVENO_ARTHROPODS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 W57
  • Cause of death: ICD-10 W57

2 out of 7 registries used, show all original rules.

1210

4. Check minimum number of events

None

1210

5. Include endpoints

None

1210

6. Filter based on genotype QC (FinnGen only)

1210

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
5
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
W50-W64

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 1210 752 458
Unadjusted period prevalence (%) 0.24 0.26 0.20
Median age at first event (years) 53.88 51.61 57.61

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1106
Matched controls
11058
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
W57
ICD-10 Finland
Bitten or stung by nonvenomous insect and other nonvenomous arthropods
4503599627370496.0
323.0
1105
103
T63.4
ICD-10 Finland
Toxic effect: Venom of other arthropods
75.2
198.0
223
37
C01CA24
ATC
epinephrine; parenteral
12.7
169.9
328
355
T78.4
ICD-10 Finland
Allergy, unspecified
14.4
158.9
286
262
T78.2
ICD-10 Finland
Anaphylactic shock, unspecified
55.7
133.3
158
33
T14.0
ICD-10 Finland
Superficial injury of unspecified body region
31.4
94.1
126
45
H02AB06
ATC
prednisolone; systemic
2.8
56.1
624
3533
R06AE07
ATC
cetirizine; oral
2.0
25.2
537
3587
Z51.6
ICD-10 Finland
Desensitization to allergens
9.8
24.2
49
52
XQ800
NOMESCO Finland
Prick test
2.9
20.3
133
500
X59
ICD-10 Finland
Exposure to unspecified factor
2.2
20.1
239
1236
S12
ICPC
Insect bite/sting
3.0
18.7
111
391
M79.6
ICD-10 Finland
Pain in limb
1.8
18.5
406
2651
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.8
17.7
418
2788
X27
ICD-10 Finland
Contact with other specified venomous animals
29.3
17.5
23
8
WQ000
NOMESCO Finland
Hyposensibilisation
12.8
17.2
30
24
R07.4
ICD-10 Finland
Chest pain, unspecified
1.9
16.9
279
1638
L50.0
ICD-10 Finland
Allergic urticaria
4.6
16.2
57
130
A02BC02
ATC
pantoprazole; systemic
1.7
15.8
650
5058
X58
ICD-10 Finland
Exposure to other specified factors
2.2
15.6
179
902
J01DB01
ATC
cefalexin; oral
1.9
15.6
898
7725
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.7
15.5
522
3833
R06AX27
ATC
desloratadine; oral
1.8
14.5
329
2136
R51.80
ICD-10 Finland
Headache
2.1
14.3
188
1004
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.0
13.3
192
1061
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.9
13.0
202
1147
M03BX02
ATC
tizanidine; oral
1.6
13.0
651
5213
N02AX02
ATC
tramadol; systemic, rectal
1.6
12.6
418
2996
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.3
12.3
118
545
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
12.2
427
3102
M54.5
ICD-10 Finland
Low back pain
1.6
11.8
353
2452
T78.3
ICD-10 Finland
Angioneurotic oedema
6.3
11.6
30
49
N02BE01
ATC
paracetamol; systemic, rectal
1.7
11.4
889
7828
J45.9
ICD-10 Finland
Asthma, unspecified
1.9
11.4
189
1093
J01FA10
ATC
azithromycin; systemic
1.6
11.4
638
5167
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.4
11.0
95
419
S06.0
ICD-10 Finland
Concussion
2.1
10.9
125
625
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.0
10.8
152
828
H02AB07
ATC
prednisone; oral
2.0
10.8
146
783
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.7
10.5
283
1900
S93.4
ICD-10 Finland
Sprain and strain of ankle
2.0
10.5
131
682
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.7
10.5
243
1566
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
10.1
459
3507
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.2
9.9
105
511
J01FF01
ATC
clindamycin; systemic
1.6
9.9
271
1827
R06AE09
ATC
levocetirizine; oral
1.8
9.8
169
988
J01MA02
ATC
ciprofloxacin; systemic
1.6
9.7
359
2608
R03AC02
ATC
salbutamol; inhalant
1.5
9.7
552
4418
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.0
9.6
122
637
S18
ICPC
Laceration/cut
1.5
9.6
397
2959
H02AB04
ATC
methylprednisolone; systemic
1.9
9.6
152
864
R03DC03
ATC
montelukast; oral
1.8
9.6
179
1074
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.7
9.5
239
1573
A92
ICPC
Allergy/allergic reaction NOS
3.2
9.4
47
149
T63.9
ICD-10 Finland
Toxic effect: Toxic effect of contact with unspecified venomous animal
+∞
9.4
9
*
M79.1
ICD-10 Finland
Myalgia
1.9
9.3
141
790
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.8
9.1
182
1117
M25.5
ICD-10 Finland
Pain in joint
1.6
8.9
291
2042
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.8
8.8
167
1009
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.7
8.7
186
1163
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.9
8.6
132
743
S01GX01
ATC
cromoglicic acid; ophthalmic
1.6
8.5
217
1427
J01AA02
ATC
doxycycline; systemic
1.5
8.4
769
6700
N03AX16
ATC
pregabalin; oral
1.6
8.4
224
1490
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
8.3
268
1870
A69.2
ICD-10 Finland
Lyme disease
2.5
8.3
63
259
L03
ICPC
Low back symptom/complaint
1.6
8.2
250
1723
A02BC05
ATC
esomeprazole; systemic
1.5
8.1
380
2882
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
2.7
8.1
55
212
U01
ICPC
Dysuria/painful urination
2.2
8.1
83
398
G43.9
ICD-10 Finland
Migraine, unspecified
2.3
8.0
75
343
R52.9
ICD-10 Finland
Pain, unspecified
2.0
8.0
96
492
Z00.0
ICD-10 Finland
General medical examination
1.6
7.7
194
1271
M01AB05
ATC
diclofenac; systemic, rectal
1.4
7.5
650
5536
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.6
7.5
215
1456
K10.3
ICD-10 Finland
Alveolitis of jaws
2.5
7.5
55
224
J01FA09
ATC
clarithromycin; systemic
1.5
7.5
316
2339
R06.0
ICD-10 Finland
Dyspnoea
1.6
7.4
220
1502
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
7.4
525
4302
R74
ICPC
Upper respiratory infection acute
1.5
7.3
318
2367
J01DA01
ATC
[U] cefalexin; systemic
1.4
7.2
608
5136
J01MA12
ATC
levofloxacin; systemic
1.7
7.1
160
1014
S60.2
ICD-10 Finland
Contusion of other parts of wrist and hand
2.4
7.1
56
238
R03BA05
ATC
fluticasone; inhalant
1.6
7.0
189
1259
Z71.8
ICD-10 Finland
Other specified counselling
1.5
7.0
244
1728
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.4
7.0
499
4079
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.8
7.0
125
742
X49
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances
5.2
7.0
20
39
R06AX22
ATC
ebastine; oral
1.6
6.9
170
1107
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
6.8
357
2751
M01AH05
ATC
etoricoxib; oral
1.4
6.8
570
4782
M03BC01
ATC
orphenadrine (citrate); systemic
1.5
6.8
231
1627
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.8
6.7
123
733
S22.3
ICD-10 Finland
Fracture of rib
2.2
6.7
64
296
SAA02
NOMESCO Finland
Basic examination of mouth
1.4
6.6
691
6014
L50.8
ICD-10 Finland
Other urticaria
3.7
6.6
27
75
ZXA05
NOMESCO Finland
Left side
1.5
6.6
215
1499
R42
ICD-10 Finland
Dizziness and giddiness
1.6
6.5
190
1288
P01AB01
ATC
metronidazole; oral, rectal
1.4
6.5
378
2964
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.6
6.5
184
1238
R20.2
ICD-10 Finland
Paraesthesia of skin
2.1
6.5
72
357
N92.0
ICD-10 Finland
Excessive and frequent menstruation with regular cycle
1.9
6.5
96
535
W84
ICD-10 Finland
Unspecified threat to breathing
70.2
6.4
7
*
R03BA02
ATC
budesonide; inhalant
1.6
6.4
180
1207
SPAT1267
SPAT
Desensitisation
14.4
6.4
10
7
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.7
6.4
141
890
R02
ICPC
Shortness of breath/dyspnoea
1.8
6.3
116
690
L12
ICPC
Hand/finger symptom/complaint
1.7
6.3
145
922
R03AK08
ATC
formoterol and beclometasone; inhalant
2.6
6.3
42
164
R60.0
ICD-10 Finland
Localized oedema
1.8
6.3
98
554
M67.4
ICD-10 Finland
Ganglion
2.1
6.2
70
349
AA1AD
NOMESCO Finland
CT of head and brain
1.5
6.2
196
1357
R07.3
ICD-10 Finland
Other chest pain
1.9
6.2
90
498
U02
ICPC
Urinary frequency/urgency
1.7
6.2
126
775
S80.0
ICD-10 Finland
Contusion of knee
2.0
6.1
70
355
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.6
6.1
144
924
L01
ICPC
Neck symptom/complaint
1.7
6.1
135
855
P06
ICPC
Sleep disturbance
1.8
6.0
98
562
A02BC03
ATC
lansoprazole; oral
1.5
6.0
255
1875

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: VWXY20_BITTEN_STUNG_NONVENO_INSECT_OTHER_NONVENO_ARTHROPODS – Bitten or stung by nonvenomous insect and other nonvenomous arthropods

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).