allergic rhinitis: Inflammation of the nasal mucous membranes caused by an IgE-mediated response to external allergens. The inflammation may also involve the mucous membranes of the sinuses, eyes, middle ear, and pharynx. Symptoms include sneezing, nasal congestion, rhinorrhea, and itching. It may lead to fatigue, drowsiness, and malaise thus causing impairment of the quality of life.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditions
|
12344 |
3. Check pre-conditions, main-only, mode, registry filtersNone 0 out of 7 registries used, show all original rules. |
0 |
4. Check minimum number of eventsNone |
0 |
5. Include endpoints |
6259 |
6. Filter based on genotype QC (FinnGen only) |
6014 |
Control definitions (FinnGen only)
Control exclude
J10_ASTHMA, ASTHMA_EXCL, ST19_ADVER_EFFEC_NOT_ELSEW_CLASSIFIED
Control conditions
not ALLERG_ASTHMA
Extra metadata
First used in FinnGen datafreeze
DF2
Similar endpoints
↥List of similar endpoints to
Asthma and allergy
based on the number of shared cases.
Broader endpoints:
- Asthma and allergy
- Allergic asthma (mode)
- Allergic asthma (mode)
- Asthma (diagnoses ohter than nonallergic)
- Asthma
Narrower endpoints:
Case counts by codes
↥FinnGen case counts by registry codes:
No data for upset plot.
No data for upset table.
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 6014 | 4264 | 1750 |
| Unadjusted period prevalence (%) | 1.44 | 1.67 | 0.88 |
| Median age at first event (years) | 24.66 | 26.25 | 20.79 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: ASTHMA_ALLERG – Asthma and allergy
GWS hits: 15
This endpoint is excluded (different definition than used in FinnGen).