Allergic urticaria

L12_URTICA_ALLERG

allergic urticaria: commonly referred to as hives, is a kind of skin rash notable for pale red, raised, itchy bumps. Hives may cause a burning or stinging sensation. Histamine and other proinflammatory substances are released from mast cells in the skin and tissues in response to the binding of allergen-bound IgE antibodies to high-affinity cell surface receptors. Basophils and other inflammatory cells are also seen to release histamine and other mediators, and are thought to play an important role, especially in chronic urticarial diseases.

Suggest a new description

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 L50.0
  • Hospital discharge: ICD-9 7080
  • Cause of death: ICD-10 L50.0
  • Cause of death: ICD-9 7080

2 out of 7 registries used, show all original rules.

3461

4. Check minimum number of events

None

3461

5. Include endpoints

None

3461

6. Filter based on genotype QC (FinnGen only)

3461

Control definitions (FinnGen only)

Control exclude
L12_URTICARIAERYTHEMA

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
L50
Name in latin
Urticaria allergica

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 34186 19774 14249
Only index persons 28832 17219 11613
Unadjusted period prevalence (%)
Whole population 0.49 0.57 0.40
Only index persons 0.56 0.63 0.44
Median age at first event (years)
Whole population 25.34 32.25 15.58
Only index persons 28.78 34.54 20.24

-FinnGen-

Key figures

All Female Male
Number of individuals 3461 2451 1010
Unadjusted period prevalence (%) 0.72 0.84 0.45
Median age at first event (years) 42.45 41.04 45.87

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
3085
Matched controls
30851
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L50.0
ICD-10 Finland
Allergic urticaria
2014.2
323.0
2756
128
L50.9
ICD-10 Finland
Urticaria, unspecified
31.0
323.0
470
178
7080A
ICD-9 Finland
Urticaria, Allergic urticaria
+∞
323.0
340
*
C01CA24
ATC
epinephrine; parenteral
10.2
323.0
747
936
H02AB06
ATC
prednisolone; systemic
3.8
267.6
1919
9254
L50.8
ICD-10 Finland
Other urticaria
102.5
232.2
254
27
R06AE07
ATC
cetirizine; oral
3.4
226.8
1925
10039
XQ800
NOMESCO Finland
Prick test
6.0
197.5
609
1221
T78.4
ICD-10 Finland
Allergy, unspecified
7.5
178.2
453
692
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
5.0
176.3
638
1524
L50.3
ICD-10 Finland
Dermatographic urticaria
74.7
125.7
143
20
H02AB07
ATC
prednisone; oral
3.2
96.4
588
2120
J01FF01
ATC
clindamycin; systemic
2.4
92.6
980
4927
T78.2
ICD-10 Finland
Anaphylactic shock, unspecified
14.8
90.5
155
110
R06AX27
ATC
desloratadine; oral
2.3
87.3
1115
6119
R06AE09
ATC
levocetirizine; oral
2.7
81.4
647
2741
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
5.5
70.4
220
425
R03DC03
ATC
montelukast; oral
2.5
69.1
638
2913
L50.1
ICD-10 Finland
Idiopathic urticaria
59.3
69.0
81
14
R03AC02
ATC
salbutamol; inhalant
1.9
67.6
1742
12357
J45.0
ICD-10 Finland
Predominantly allergic asthma
3.0
62.7
404
1479
R06AX22
ATC
ebastine; oral
2.3
61.7
658
3213
H02AB04
ATC
methylprednisolone; systemic
2.5
59.6
515
2249
N05BB01
ATC
hydroxyzine; systemic
3.5
59.0
297
907
J45.9
ICD-10 Finland
Asthma, unspecified
2.3
57.5
621
3036
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.9
57.0
1205
7778
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.9
56.3
1178
7566
A02BC02
ATC
pantoprazole; systemic
1.8
53.3
1834
13832
M79.6
ICD-10 Finland
Pain in limb
1.9
50.9
1097
7055
E0000UV
ATC
NA
1.8
50.4
1279
8682
A92
ICPC
Allergy/allergic reaction NOS
4.4
47.3
178
419
T78.3
ICD-10 Finland
Angioneurotic oedema
8.6
46.2
103
124
J01DB01
ATC
cefalexin; oral
1.9
45.8
2503
21357
N02AX02
ATC
tramadol; systemic, rectal
1.8
45.7
1148
7695
L27.0
ICD-10 Finland
Generalized skin eruption due to drugs and medicaments
8.3
45.3
103
128
R01AD09
ATC
mometasone; nasal
1.7
44.0
1446
10482
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.7
43.9
1536
11338
D07AA02
ATC
hydrocortisone; topical
2.2
43.1
529
2706
L20.0
ICD-10 Finland
Besnier prurigo
2.7
42.8
328
1322
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
2.0
42.8
617
3375
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.1
42.2
570
3035
Z3231
NOMESCO Finland
Registered nurse
1.8
41.7
832
5133
J01FA10
ATC
azithromycin; systemic
1.7
41.3
1895
15003
R06AX13
ATC
loratadine; oral
2.0
40.9
574
3099
XQ802
NOMESCO Finland
Epicutan test
3.6
40.1
189
544
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.9
39.8
779
4757
D07AB02
ATC
hydrocortisone butyrate; topical
1.8
39.2
859
5446
Y57
ICD-10 Finland
Adverse effects in the therapeutic use of other and unspecified drugs and medicaments
5.5
38.7
119
225
N02BE01
ATC
paracetamol; systemic, rectal
1.8
38.5
2514
21822
J01AA02
ATC
doxycycline; systemic
1.7
38.0
2206
18421
R03BA05
ATC
fluticasone; inhalant
1.9
38.0
618
3526
R06.0
ICD-10 Finland
Dyspnoea
1.9
37.9
689
4091
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.0
37.1
587
3311
N03AX16
ATC
pregabalin; oral
1.9
36.4
661
3918
D07AC01
ATC
betamethasone; topical
1.7
35.7
958
6429
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.0
35.6
542
3005
M54.5
ICD-10 Finland
Low back pain
1.7
35.6
997
6772
J01FA06
ATC
roxithromycin; oral
1.7
35.5
1161
8239
Z01.8
ICD-10 Finland
Other specified special examinations
1.9
35.5
645
3818
D07AB08
ATC
desonide; topical
2.3
35.4
361
1684
M25.5
ICD-10 Finland
Pain in joint
1.7
35.3
859
5591
R50.9
ICD-10 Finland
Fever, unspecified
2.1
35.1
455
2366
J01DA01
ATC
[U] cefalexin; systemic
1.6
34.9
1841
14783
J01MA02
ATC
ciprofloxacin; systemic
1.7
34.6
1013
6957
J30.10
ICD-10 Finland
Allergic rhinitis due to pollen
2.7
34.5
254
996
X59
ICD-10 Finland
Exposure to unspecified factor
1.9
34.4
578
3320
L27.2
ICD-10 Finland
Dermatitis due to ingested food
6.6
33.0
87
136
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.6
32.5
1276
9436
J01MA12
ATC
levofloxacin; systemic
2.0
32.4
483
2650
T78.0
ICD-10 Finland
Anaphylactic shock due to adverse food reaction
29.0
32.0
43
15
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
31.9
748
4790
A02BC05
ATC
esomeprazole; systemic
1.6
31.8
1114
7988
D07AC13
ATC
mometasone; topical
1.7
31.4
818
5400
T88.7
ICD-10 Finland
Unspecified adverse effect of drug or medicament
5.8
31.4
91
161
R03BA02
ATC
budesonide; inhalant
1.9
30.9
557
3267
X49
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances
9.2
30.8
65
72
J01FA09
ATC
clarithromycin; systemic
1.6
30.2
965
6729
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.7
29.8
739
4793
R51.80
ICD-10 Finland
Headache
1.9
29.7
517
2994
N02AJ06
ATC
codeine and paracetamol; systemic
1.6
29.3
1046
7492
R03AK06
ATC
salmeterol and fluticasone; inhalant
2.0
28.7
390
2054
N03AX12
ATC
gabapentin; oral
2.0
28.1
426
2341
S01GX01
ATC
cromoglicic acid; ophthalmic
1.7
27.7
655
4181
XF400
NOMESCO Finland
ECG with 12 standard connections
1.9
27.6
422
2327
E000001
ATC
NA
1.7
27.4
643
4090
Z51.6
ICD-10 Finland
Desensitization to allergens
5.3
27.1
84
162
TPH04
NOMESCO Finland
Cathetrisation of vein
1.8
27.0
548
3332
R01AD08
ATC
fluticasone; nasal
1.6
26.8
849
5866
L20.9
ICD-10 Finland
Atopic dermatitis, unspecified
3.1
26.6
154
519
P01AB01
ATC
metronidazole; oral, rectal
1.5
26.3
1134
8446
L50
ICD-10 Finland
Urticaria
5.7
26.1
76
136
M03BX02
ATC
tizanidine; oral
1.5
26.0
1745
14329
L50.2
ICD-10 Finland
Urticaria due to cold and heat
60.5
26.0
30
5
XQ820
NOMESCO Finland
Exposure to medicinal substance
12.2
26.0
47
39
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.8
25.9
484
2860
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.6
25.7
770
5237
X58
ICD-10 Finland
Exposure to other specified factors
1.9
25.6
414
2327
R11
ICD-10 Finland
Nausea and vomiting
2.2
25.5
266
1247
A02BA02
ATC
ranitidine; systemic
1.8
25.5
492
2937
R07.4
ICD-10 Finland
Chest pain, unspecified
1.7
25.2
654
4268
R42
ICD-10 Finland
Dizziness and giddiness
1.7
25.2
548
3399
R03AK07
ATC
formoterol and budesonide; inhalant
1.7
25.0
562
3518
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.7
24.8
539
3339
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.1
24.8
308
1559
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.3
24.8
249
1149
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.8
24.6
518
3175
A46
ICD-10 Finland
Erysipelas
2.0
24.4
320
1660
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
1.6
24.3
670
4444
X57
ICD-10 Finland
Unspecified privation
4.3
24.0
90
213
D07BA04
ATC
hydrocortisone and antiseptics; topical
2.0
23.9
340
1818
M54.4
ICD-10 Finland
Lumbago with sciatica
1.8
23.8
462
2759
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.2
23.6
243
1133
M03BC01
ATC
orphenadrine (citrate); systemic
1.6
23.4
675
4521
A03FA01
ATC
metoclopramide; systemic, rectal
1.7
23.4
553
3508
317
Kela drug reimbursment
Topical pimecrolimus and tacrolimus
4.5
23.1
83
188
T88.6
ICD-10 Finland
Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
17.3
23.1
36
21
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.8
23.0
156
580
J01MA14
ATC
moxifloxacin; systemic
2.2
23.0
244
1155
L50.5
ICD-10 Finland
Cholinergic urticaria
120.9
22.6
24
*
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
22.5
721
4959
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.8
22.4
391
2251
R01AD12
ATC
fluticasone furoate; nasal
1.5
22.2
924
6757
R4110
NOMESCO Finland
Physiotherapy
1.6
22.1
681
4638
R03AC03
ATC
terbutaline; inhalant
1.8
21.9
419
2486
Z3226
NOMESCO Finland
Physiotherapist
1.7
21.8
512
3235
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.8
21.6
386
2240
ZXD10
NOMESCO Finland
Scheduled procedure
1.5
21.4
1029
7758
UJF32
NOMESCO Finland
Coloscopy
1.6
21.3
617
4128
N05CF01
ATC
zopiclone; oral
1.5
21.0
780
5543
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
2.8
20.9
140
518
J45.1
ICD-10 Finland
Nonallergic asthma
2.2
20.8
222
1052
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.1
20.7
246
1221
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.5
20.6
855
6230
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.0
20.4
284
1503
ZXE00
NOMESCO Finland
One hour or less
1.5
20.4
1099
8464
J01FA01
ATC
erythromycin; systemic
1.7
20.1
469
2949
E000002
ATC
NA
1.8
20.1
364
2116
L17
ICPC
Foot/toe symptom/complaint
1.6
20.1
664
4585
N30.0
ICD-10 Finland
Acute cystitis
1.8
20.0
407
2456
M70.6
ICD-10 Finland
Trochanteric bursitis
1.9
19.8
312
1730
AA1AD
NOMESCO Finland
CT of head and brain
1.6
19.7
525
3426
J46
ICD-10 Finland
Status asthmaticus
3.3
19.7
99
303
J02AC01
ATC
fluconazole; systemic
1.4
19.4
1193
9406
R01BA52
ATC
pseudoephedrine, combinations; oral
1.5
19.4
818
5968
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
2.0
19.3
247
1264
XG474
NOMESCO Finland
Exhalation nntrogen oxide
3.0
19.3
112
379
A06AC01
ATC
ispaghula (psylla seeds); oral
1.6
19.3
590
3992
WX110
NOMESCO Finland
Local anesthesy
1.4
19.2
2031
17700
G44.2
ICD-10 Finland
Tension-type headache
1.7
19.2
403
2457
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.0
19.1
268
1424
R03BB04
ATC
tiotropium bromide; inhalant
2.1
19.1
215
1045
ZXE10
NOMESCO Finland
More than one and less than three hours
1.5
19.1
929
6984
A02BC01
ATC
omeprazole; systemic
1.5
19.0
689
4854
L03
ICPC
Low back symptom/complaint
1.5
18.9
667
4671
N06AX11
ATC
mirtazapine; oral
1.5
18.9
842
6211
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.8
18.7
321
1830
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.9
18.7
275
1486
Z2221
NOMESCO Finland
Medical doctor
1.5
18.7
781
5673
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.8
18.6
368
2198
J45.8
ICD-10 Finland
Mixed asthma
3.1
18.6
106
354
ZXD05
NOMESCO Finland
Urgent procedure
1.5
18.5
857
6365
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.5
18.5
751
5421
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.9
18.5
303
1704
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
1.8
18.5
362
2159
J20
ICD-10 Finland
Acute bronchitis
1.9
18.4
279
1524
J01FA15
ATC
telithromycin; oral
1.9
18.0
282
1557
R06AX26
ATC
fexofenadine; oral
2.1
17.9
217
1084
XG410
NOMESCO Finland
Flow-volume spirometry
2.7
17.9
126
482
XQ801
NOMESCO Finland
Intracutantest
8.7
17.9
38
44
N06AX21
ATC
duloxetine; oral
1.8
17.8
306
1744
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
2.2
17.8
191
906
7089X
ICD-9 Finland
Urticaria, unspecified
+∞
17.7
17
*
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.3
17.7
173
788
S98
ICPC
Urticaria
7.5
17.6
41
55
C03CA01
ATC
furosemide; systemic
1.6
17.5
531
3575
Z71.8
ICD-10 Finland
Other specified counselling
1.5
17.5
698
5011
R02
ICPC
Shortness of breath/dyspnoea
1.8
17.5
314
1819
E000007
ATC
NA
2.2
17.3
181
851
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.9
17.2
109
390
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.9
17.1
275
1536
R03BA01
ATC
beclometasone; inhalant
1.7
17.1
372
2287
M01AH05
ATC
etoricoxib; oral
1.4
16.9
1537
12889
E000003
ATC
NA
2.4
16.8
148
639
R96
ICPC
Asthma
1.9
16.7
243
1305
R03AC12
ATC
salmeterol; inhalant
2.6
16.7
122
476
R53
ICD-10 Finland
Malaise and fatigue
1.6
16.6
540
3695
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
16.5
915
7014
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
16.5
1143
9128
344
Kela drug reimbursment
Omalizumab
170.8
16.5
17
*
J05AB01
ATC
aciclovir; systemic
1.5
16.5
568
3938
C07AB07
ATC
bisoprolol; oral
1.4
16.4
966
7488
J45
ICD-10 Finland
Asthma
1.8
16.4
278
1580
UKC02
NOMESCO Finland
Cystoscopy
1.8
16.3
313
1852
M01AE02
ATC
naproxen; oral, rectal
1.4
16.3
1622
13772
E000006
ATC
NA
2.0
16.2
201
1018
R60.0
ICD-10 Finland
Localized oedema
1.9
16.2
253
1398
S29
ICPC
Skin symptom/complaint other
1.6
16.2
435
2835
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.9
16.2
229
1221
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.4
16.1
821
6191
R03AK08
ATC
formoterol and beclometasone; inhalant
2.7
16.0
114
439
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.0
15.9
207
1068
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.7
15.9
343
2102
H04.10
ICD-10 Finland
Dry eye syndrome
1.9
15.9
255
1421
B01AB05
ATC
enoxaparin; parenteral
1.5
15.6
687
5017
N02AA05
ATC
oxycodone; systemic
1.8
15.4
301
1791
R52.9
ICD-10 Finland
Pain, unspecified
1.9
15.3
230
1251
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.9
15.3
226
1222
WQ000
NOMESCO Finland
Hyposensibilisation
6.1
15.3
41
68
A02BC03
ATC
lansoprazole; oral
1.5
15.2
686
5036
R03BA08
ATC
ciclesonide; inhalant
1.9
15.1
231
1266
M79.1
ICD-10 Finland
Myalgia
1.7
15.1
360
2270
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.0
15.1
188
954
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
1.9
15.1
245
1372
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.8
15.0
277
1616
H02AB09
ATC
hydrocortisone; systemic
3.0
15.0
86
289
D11AH01
ATC
tacrolimus; topical
4.5
15.0
52
116
D02AX
ATC
Other emollients and protectives
2.5
14.9
116
472
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
14.9
2069
18423
TDM10
NOMESCO Finland
Puncture of maxillary antrum
2.4
14.9
127
540
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.7
14.8
309
1871
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.6
14.7
104
401
S06.0
ICD-10 Finland
Concussion
1.8
14.7
286
1700
Z2446
NOMESCO Finland
Social worker
2.0
14.6
203
1073
S88
ICPC
Dermatitis contact/allergic
3.2
14.6
75
235
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.7
14.5
345
2171
WX002
NOMESCO Finland
Sedation and analgesia
1.6
14.4
463
3148
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.5
14.3
619
4495
M01AB05
ATC
diclofenac; systemic, rectal
1.3
14.2
1735
15072
R60.9
ICD-10 Finland
Oedema, unspecified
2.4
14.2
123
529
M03BC51
ATC
orphenadrine, combinations; systemic
1.4
14.2
731
5496
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.6
14.2
446
3017
J01DC02
ATC
cefuroxime; systemic
2.1
14.2
172
863
G47.3
ICD-10 Finland
Sleep apnoea
1.5
14.1
458
3122
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.3
14.1
1523
12980
R74
ICPC
Upper respiratory infection acute
1.4
14.1
905
7085
XQ899
NOMESCO Finland
Other assessment of skin
8.9
13.9
29
33
ZY010
NOMESCO Finland
Hospital outpatient
2.1
13.9
168
840
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
1.9
13.8
195
1038
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.7
13.8
327
2055
R00.2
ICD-10 Finland
Palpitations
1.9
13.8
203
1098
R55
ICD-10 Finland
Syncope and collapse
1.8
13.8
238
1358
W00
ICD-10 Finland
Fall on same level involving ice and snow
1.7
13.8
271
1616
G43.9
ICD-10 Finland
Migraine, unspecified
1.9
13.7
200
1078
JN3AD
NOMESCO Finland
Abdominal CT examination
2.0
13.7
179
923
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.9
13.6
218
1214
R07.3
ICD-10 Finland
Other chest pain
1.8
13.6
227
1281
D07AD01
ATC
clobetasol; topical
1.6
13.6
374
2448
134
Kela drug reimbursment
General erythroderma
+∞
13.5
13
*
70890
ICD-8 Finland
Urticaria, Acuta
+∞
13.5
13
*
7088A
ICD-9 Finland
Urticaria, Other specified urticaria[URTICARIA CHRONICA NUD]
+∞
13.5
13
*
A01
ICPC
Pain general/multiple sites
1.9
13.5
198
1067
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.4
13.5
820
6346
R03DX05
ATC
omalizumab; parenteral
140.6
13.5
14
*
K02.1
ICD-10 Finland
Caries of dentine
1.3
13.4
1655
14338
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.6
13.4
346
2229
R06.2
ICD-10 Finland
Wheezing
2.2
13.3
134
622
M54
ICD-10 Finland
Dorsalgia
1.7
13.2
307
1920
R05
ICPC
Cough
1.4
13.1
608
4466
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.5
13.1
517
3676
J30.3
ICD-10 Finland
Other allergic rhinitis
2.3
13.1
116
506
L23.3
ICD-10 Finland
Allergic contact dermatitis due to drugs in contact with skin
6.5
13.1
33
51
M01AH01
ATC
celecoxib; oral (coxibs)
1.6
12.8
401
2708
K30
ICD-10 Finland
Functional dyspepsia
1.7
12.7
274
1678
ZX120
NOMESCO Finland
Intravenous
1.8
12.7
235
1373
M04AA01
ATC
allopurinol; systemic
1.8
12.7
217
1236
J01EA01
ATC
trimethoprim; systemic
1.4
12.6
660
4961
D07CC01
ATC
betamethasone and antibiotics; topical
1.6
12.6
315
2010
J01DA06
ATC
[U] cefuroxime; systemic
1.6
12.6
385
2583
L04AD01
ATC
ciclosporin; systemic
3.2
12.5
64
201
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.5
12.5
548
3981
N06AB10
ATC
escitalopram; oral
1.4
12.5
588
4333
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.3
12.4
1429
12198
L04AA01
ATC
[U] ciclosporin; systemic
3.9
12.3
50
131
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
1.9
12.3
190
1046
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
1.9
12.2
192
1064
A07AA02
ATC
nystatin; oral
2.0
12.2
151
763
A01AB09
ATC
miconazole; local oral
1.8
12.2
224
1303
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
2.0
12.2
153
778
ZXA05
NOMESCO Finland
Left side
1.4
12.2
557
4080
R20.2
ICD-10 Finland
Paraesthesia of skin
1.9
12.1
179
968
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.8
12.1
198
1111
501
Kela drug reimbursment
Cow's milk and / or soy protein allergy in young children
3.9
12.1
48
123
R52.2
ICD-10 Finland
Other chronic pain
2.5
11.9
90
362
R03AK04
ATC
salbutamol and sodium cromoglicate; inhalant
6.8
11.9
29
43
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.5
11.8
415
2874
XF600
NOMESCO Finland
Bloodpressure measurement
1.9
11.8
165
878
R01AD11
ATC
triamcinolone; nasal
1.7
11.7
235
1405
E66.01
ICD-10 Finland
Obesity due to excess calories
1.8
11.7
223
1312
M79.7
ICD-10 Finland
Fibromyalgia
2.4
11.7
99
424
N05AH04
ATC
quetiapine; oral
1.5
11.7
455
3223
WX290
NOMESCO Finland
Other blockade of nerve
1.3
11.7
1306
11065
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.6
11.7
334
2207
S18
ICPC
Laceration/cut
1.3
11.6
990
8058
H01
ICPC
Ear pain/earache
1.6
11.6
318
2077
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
2.1
11.6
131
642
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.6
11.5
304
1966
N03AE01
ATC
clonazepam; systemic
2.0
11.5
139
696
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.4
11.5
673
5150
R5140
NOMESCO Finland
Monitoring the use of the aid
1.8
11.5
214
1251
A03
ICPC
Fever
1.5
11.5
486
3499
70891
ICD-8 Finland
Urticaria, Recidivans, Chronica
+∞
11.5
11
*
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
1.8
11.4
187
1051
P01BA02
ATC
hydroxychloroquine; oral
1.8
11.4
205
1189
N05BA01
ATC
diazepam; systemic, rectal
1.6
11.4
313
2043
SPAT1263
SPAT
Sampling
1.3
11.4
1147
9563
R05
ICD-10 Finland
Cough
1.5
11.4
470
3370
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.6
11.4
276
1747
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.5
11.4
383
2627
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.2
11.4
112
514
ZXA10
NOMESCO Finland
Bilateral
1.5
11.3
427
3001
W84
ICD-10 Finland
Unspecified threat to breathing
8.9
11.2
23
26
R05FB02
ATC
cough suppressants and expectorants
1.3
11.2
878
7044
C08CA05
ATC
nifedipine; systemic
2.0
11.2
139
706
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
11.2
1341
11450
R35
ICD-10 Finland
Polyuria
2.1
11.2
126
617
Z2445
NOMESCO Finland
Psychologist
2.0
11.1
134
671
WZC30
NOMESCO Finland
Teaching
1.6
11.1
295
1911
T78.1
ICD-10 Finland
Other adverse food reactions, not elsewhere classified
20.1
11.1
16
8
UJF30
NOMESCO Finland
Ileoscopy through colon
1.7
11.1
226
1359
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.4
11.1
706
5477
R31
ICD-10 Finland
Unspecified haematuria
1.8
11.1
176
979
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
1.8
11.1
178
995
J31.0
ICD-10 Finland
Chronic rhinitis
1.7
11.0
215
1275
R03AL02
ATC
salbutamol and ipratropium bromide; inhalant
5.2
11.0
33
64
J01MA06
ATC
norfloxacin; oral
1.6
11.0
325
2159
J05AB11
ATC
valaciclovir; oral
1.6
10.9
327
2182
ZXD20
NOMESCO Finland
Day surgery
1.6
10.9
321
2131
N05BA04
ATC
oxazepam; oral
1.4
10.9
623
4749
R01AD05
ATC
budesonide; nasal
1.7
10.8
206
1214
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.6
10.7
268
1709
XQ818
NOMESCO Finland
Conjunctival allergen provocation test
17.9
10.7
16
9
S93.4
ICD-10 Finland
Sprain and strain of ankle
1.6
10.7
310
2054
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.8
10.7
178
1005
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.8
10.6
169
942
D02AE01
ATC
carbamide; topical
1.8
10.6
176
994
D11AH02
ATC
pimecrolimus; topical
7.0
10.5
25
36
H53.1
ICD-10 Finland
Subjective visual disturbances
1.9
10.5
151
812
M22.4
ICD-10 Finland
Chondromalacia patellae
2.2
10.5
99
448
NA1AD
NOMESCO Finland
Cervical spine CT examination
2.3
10.4
98
441
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.4
10.4
667
5174
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.6
10.4
286
1867
I10
ICD-10 Finland
Essential (primary) hypertension
1.3
10.4
1101
9217
D07BC01
ATC
betamethasone and antiseptics; topical
1.6
10.4
276
1787
N06AA09
ATC
amitriptyline; systemic
1.7
10.3
219
1335
D07CA01
ATC
hydrocortisone and antibiotics; topical
1.5
10.3
338
2299
H03AA01
ATC
levothyroxine sodium; systemic
1.4
10.3
579
4391
R03AK10
ATC
vilanterol and fluticasone furoate; inhalant
2.2
10.3
105
492
SPAT1254
SPAT
Administration of medicine
1.5
10.3
373
2598
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.3
10.2
1593
14023
SGA01
NOMESCO Finland
Tooth opening as first aid
1.5
10.2
420
3006
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.7
10.2
227
1405
C10AC01
ATC
colestyramine; oral
2.6
10.1
70
270
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
1.6
10.1
241
1516
N03AG01
ATC
valproic acid; systemic, rectal
1.8
10.1
161
899
H60.9
ICD-10 Finland
Otitis externa, unspecified
1.8
10.1
172
982
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.7
10.1
210
1274
Z00.0
ICD-10 Finland
General medical examination
1.4
10.1
465
3404
M54.2
ICD-10 Finland
Cervicalgia
1.8
10.0
180
1043
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
1.9
10.0
152
835
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.6
9.9
230
1438
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
1.9
9.9
134
706
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.7
9.9
220
1360
N03AX09
ATC
lamotrigine; oral
1.9
9.9
147
798
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.7
9.9
203
1227
L26
ICD-10 Finland
Exfoliative dermatitis
16.7
9.9
15
9
A02BC04
ATC
rabeprazole; oral
1.7
9.8
204
1236
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.6
9.8
269
1756
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.4
9.8
530
3989
R03DA04
ATC
theophylline; systemic, rectal
2.1
9.8
106
508
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.5
9.8
363
2541
M89.0
ICD-10 Finland
Algoneurodystrophy
4.7
9.8
32
69
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
1.8
9.8
158
886
N06AX16
ATC
venlafaxine; oral
1.5
9.8
364
2547
WX320
NOMESCO Finland
Spinalanesthesy
1.4
9.8
506
3779
R03CC02
ATC
salbutamol; systemic
1.7
9.7
218
1350
7806A
ICD-9 Finland
General symptoms, Pyrexia of unknown origin
4.5
9.7
33
74
L16
ICPC
Ankle symptom/complaint
1.6
9.7
259
1680
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.4
9.7
461
3390
Z03.8
ICD-10 Finland
Observation for other suspected diseases and conditions
2.0
9.7
119
604
R09
ICPC
Sinus symptom/complaint
1.6
9.6
222
1387
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
1.9
9.6
147
808
L12
ICPC
Hand/finger symptom/complaint
1.5
9.6
372
2627
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
1.7
9.6
197
1189
4930A
ICD-9 Finland
Asthma, Extrinsic asthma[EXTRINSIC ASTHMA SINE EXACERBATIONE]
3.6
9.6
41
114
R06.4
ICD-10 Finland
Hyperventilation
2.9
9.6
56
195
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.3
9.5
867
7084
ZX112
NOMESCO Finland
Subcutaneous
2.9
9.5
55
190
T63.4
ICD-10 Finland
Toxic effect: Venom of other arthropods
3.7
9.5
39
105
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
1.8
9.5
155
872
K10.3
ICD-10 Finland
Alveolitis of jaws
1.9
9.5
130
689
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.5
9.5
393
2817
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
2.2
9.5
94
436
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.5
9.4
346
2417
R00.0
ICD-10 Finland
Tachycardia, unspecified
2.1
9.4
108
534
R06AE08
ATC
NA
3.9
9.4
37
96
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
1.8
9.4
145
801
WXQ27
NOMESCO Finland
UVB narrow spectrum light therapy
3.8
9.4
38
101
7088B
ICD-9 Finland
Urticaria, Other specified urticaria[URTICARIA RECURRENS NUD]
+∞
9.4
9
*
D11AX15
ATC
[U] pimecrolimus; topical
8.0
9.3
20
25
R03DC01
ATC
zafirlukast; oral
3.5
9.3
42
122
ZXA00
NOMESCO Finland
Right side
1.4
9.3
583
4498
W19
ICD-10 Finland
Unspecified fall
1.7
9.3
212
1317
R01AC01
ATC
cromoglicic acid; nasal
2.0
9.3
120
620
G97.0
ICD-10 Finland
Cerebrospinal fluid leak from spinal puncture
3.1
9.3
48
155
L29.9
ICD-10 Finland
Pruritus, unspecified
2.6
9.3
64
248
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
2.1
9.2
98
469
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
2.1
9.2
96
456
J30.4
ICD-10 Finland
Allergic rhinitis, unspecified
2.1
9.2
103
504
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
1.8
9.2
144
799
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.4
9.2
457
3384
T36
ICD-10 Finland
Poisoning by systemic antibiotics
1.9
9.2
126
668
6918B
ICD-9 Finland
Atopic dermatitis and related conditions, Other atopic dermatitis and related conditions[ECZEMA ATOPICUM]
3.8
9.2
37
98
T90
ICPC
Diabetes non-insulin dependent
1.4
9.2
407
2953
D07AC14
ATC
methylprednisolone aceponate; topical
2.0
9.2
117
601
XQ830
NOMESCO Finland
Exposure to foodstuff
13.7
9.2
15
11
XF402
NOMESCO Finland
ECG with work load test
1.6
9.1
209
1303
R01AD01
ATC
beclometasone; nasal
1.5
9.1
374
2673
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.3
9.1
916
7576
SPAT1260
SPAT
Consultation of another employee
1.4
9.1
435
3198
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
1.7
9.1
207
1288
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
1.8
9.1
157
899
WX892
NOMESCO Finland
Monitored bed care
1.8
9.1
161
932
D11AX14
ATC
[U] tacrolimus; topical
5.1
9.1
27
53
J01
ICD-10 Finland
Acute sinusitis
1.9
9.0
138
758
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
1.9
9.0
122
642
N30.9
ICD-10 Finland
Cystitis, unspecified
1.9
9.0
136
746
M02AA07
ATC
piroxicam; topical
1.3
9.0
803
6535
E66.9
ICD-10 Finland
Obesity, unspecified
2.1
9.0
96
461
UDH02
NOMESCO Finland
Rhinopharyngoscopy
1.8
9.0
158
911
K04.1
ICD-10 Finland
Necrosis of pulp
1.6
9.0
260
1723
N03AF01
ATC
carbamazepine; oral, rectal
2.0
9.0
107
537
L23.9
ICD-10 Finland
Allergic contact dermatitis, unspecified cause
4.1
8.9
33
81
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.7
8.9
200
1240
P06
ICPC
Sleep disturbance
1.6
8.9
238
1546
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.1
8.9
100
491
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
1.5
8.9
266
1775
S40.0
ICD-10 Finland
Contusion of shoulder and upper arm
2.1
8.8
100
493
C09CA06
ATC
candesartan; oral
1.4
8.8
460
3438
A10BK03
ATC
empagliflozin; oral
1.9
8.8
131
716
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
2.0
8.8
104
522
R03AC13
ATC
formoterol; inhalant
2.0
8.8
114
591
R06AX18
ATC
acrivastine; oral
2.4
8.7
70
293
NG1BA
NOMESCO Finland
Knee extensive X-ray examination
2.8
8.7
53
191
SHA01
NOMESCO Finland
Correction of physiology of bite - simple therapy visit
1.5
8.7
299
2057
R4120
NOMESCO Finland
Occupational therapy
1.8
8.7
150
858
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.4
8.7
384
2782
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.3
8.7
642
5081
N03AX11
ATC
topiramate; oral
2.3
8.6
79
355
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
1.7
8.6
182
1109
C08CA01
ATC
amlodipine; oral
1.3
8.6
630
4978
SXA20
NOMESCO Finland
Local application of medicine to mouth
1.7
8.5
166
988
103
Kela drug reimbursment
Diabetes, insulin-treated
1.4
8.5
485
3682
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
1.8
8.5
150
869
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.6
8.4
242
1601
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
2.2
8.4
79
357
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
1.5
8.4
277
1888
D11
ICPC
Diarrhoea
1.5
8.4
312
2182
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
1.9
8.4
119
640
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
2.1
8.4
87
415
R21
ICPC
Throat symptom/complaint
1.3
8.3
620
4903
XF404
NOMESCO Finland
Ambulatory ECG
1.7
8.3
180
1106
R05FA02
ATC
opium derivatives and expectorants; systemic
1.3
8.3
994
8389
NK4AT
NOMESCO Finland
Puncture of joint with ultrasound guidance not elsewher classified
5.0
8.3
25
50
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
1.8
8.3
127
702
D09AB01
ATC
zinc bandage without supplements; topical
2.9
8.3
49
173
M53.1
ICD-10 Finland
Cervicobrachial syndrome
1.5
8.3
267
1812
NGA30
NOMESCO Finland
Exploration of knee joint, arthroscopic
1.9
8.3
124
677
C09AA05
ATC
ramipril; oral
1.4
8.3
413
3059
A06AD11
ATC
lactulose; oral
1.5
8.3
268
1822
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
2.1
8.2
90
436
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
1.9
8.2
120
652
NF1AA
NOMESCO Finland
Hip X-ray examination
1.7
8.1
163
981
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
1.8
8.1
140
806
A77
ICPC
Viral disease other/NOS
2.0
8.1
101
519
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
1.7
8.1
162
973
D06AX01
ATC
fusidic acid; topical (antibiotics for topical use)
1.5
8.1
244
1634
W57
ICD-10 Finland
Bitten or stung by nonvenomous insect and other nonvenomous arthropods
2.2
8.1
80
374
UJD02
NOMESCO Finland
Gastroscopy
1.9
8.1
105
549
A02BA04
ATC
nizatidine; systemic
1.7
8.0
153
905
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
1.8
8.0
126
705
L04AX01
ATC
azathioprine; systemic
1.9
8.0
114
615
TNG10
NOMESCO Finland
Puncture of knee
3.5
8.0
35
101
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
1.8
7.9
131
742
K07.60
ICD-10 Finland
Snapping jaw
1.7
7.9
145
846
C03DA01
ATC
spironolactone; oral
1.6
7.9
195
1242
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
1.9
7.9
113
608
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
2.1
7.9
88
432
M01AH02
ATC
rofecoxib; oral
1.5
7.9
252
1708
V700A
ICD-9 Finland
General medical examination, Routine general medical examination at a health care facility
2.3
7.9
67
289
N05CF02
ATC
zolpidem; oral
1.4
7.9
419
3140
M23.8
ICD-10 Finland
Other internal derangements of knee
2.0
7.9
95
483
TKC20
NOMESCO Finland
Catheterisation of bladder
1.8
7.8
128
722
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.7
7.8
163
990
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
1.8
7.8
126
710
R03BB01
ATC
ipratropium bromide; inhalant
2.3
7.8
70
313
J30.0
ICD-10 Finland
Vasomotor rhinitis
2.4
7.8
62
262
EBA00
NOMESCO Finland
Extraction of tooth
1.3
7.8
846
7045
M19.0
ICD-10 Finland
Primary arthrosis of other joints
1.6
7.8
187
1184
L03.9
ICD-10 Finland
Cellulitis, unspecified
2.7
7.7
51
194
L53.9
ICD-10 Finland
Erythematous condition, unspecified
4.4
7.7
26
59
M77.1
ICD-10 Finland
Lateral epicondylitis
1.6
7.7
180
1127
TLC00
NOMESCO Finland
Insertion of intrauterine device
1.6
7.7
185
1170
L04AB04
ATC
adalimumab; parenteral
2.5
7.7
55
219
395
Kela drug reimbursment
Dupilumab
45.1
7.7
9
*
C07AA05
ATC
propranolol; systemic
1.3
7.7
496
3835
SAA02
NOMESCO Finland
Basic examination of mouth
1.2
7.7
1880
17180
A04
ICPC
Weakness/tiredness general
1.4
7.7
318
2276
R52.0
ICD-10 Finland
Acute pain
2.1
7.7
86
423
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
1.7
7.6
160
976
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
2.6
7.6
53
206
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.3
7.6
494
3822
C10AA07
ATC
rosuvastatin; oral
1.4
7.6
436
3304
L28
ICPC
Limited function/disability (L)
1.5
7.6
304
2157
N06AB04
ATC
citalopram; systemic
1.3
7.6
523
4084
N03AF02
ATC
oxcarbazepine; oral
2.1
7.6
81
390
XQ810
NOMESCO Finland
Physical test for urticaria
25.1
7.6
10
*
X44
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
2.8
7.6
45
161
JN4BD
NOMESCO Finland
Extensive body CT
1.6
7.6
199
1290
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
2.7
7.5
49
185
H57.1
ICD-10 Finland
Ocular pain
2.0
7.5
87
432
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.4
7.5
388
2893
J04BA02
ATC
dapsone; oral
5.7
7.5
20
35
ZXE20
NOMESCO Finland
More than three and less than five hours
1.5
7.5
290
2045
WVA20
NOMESCO Finland
Medicine administration
2.5
7.5
57
235
M01AX17
ATC
nimesulide; oral
1.3
7.5
483
3732
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
2.7
7.5
48
178
Z00.8
ICD-10 Finland
Other general examinations
1.6
7.5
173
1084
KMAK
NOMESCO Finland
NA
1.2
7.5
1421
12612
TQW80
NOMESCO Finland
Local dermatologic skincare
2.4
7.5
60
255
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
2.1
7.5
78
374
K04.0
ICD-10 Finland
Pulpitis
1.5
7.4
257
1773
L20.8
ICD-10 Finland
Other atopic dermatitis
3.3
7.4
35
107
ND1AA
NOMESCO Finland
Wrist X-ray examination
1.7
7.4
141
837
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.4
7.4
311
2230
ZYC01
NOMESCO Finland
Remote contact by phone
1.8
7.4
117
653
E931A
ICD-9 Finland
Other anti-infectives[SULFONAMIDIT]
80.3
7.4
8
*
M01AC06
ATC
meloxicam; systemic, rectal
1.3
7.4
810
6741
KCV04
NOMESCO Finland
Distension of bladder with fluid
4.2
7.4
26
62
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
1.5
7.4
294
2086
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.2
7.4
1467
13077
L40.0
ICD-10 Finland
Psoriasis vulgaris
1.9
7.4
95
495
G40.9
ICD-10 Finland
Epilepsy, unspecified
2.1
7.3
77
369
78559
ICD-8 Finland
Symptoms referable to abdomen and lower gastro-intestinal tract, Colica abdominalis NUD
2.1
7.3
77
370
N02AC04
ATC
dextropropoxyphene; oral
2.2
7.3
74
348
S83.6
ICD-10 Finland
Sprain and strain of other and unspecified parts of knee
1.8
7.3
120
680
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
2.0
7.3
90
459
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
2.0
7.3
82
406
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.5
7.3
290
2056
M54.8
ICD-10 Finland
Other dorsalgia
1.9
7.3
96
502
N89
ICPC
Migraine
1.9
7.3
108
590
K08.80
ICD-10 Finland
Toothache NOS
1.6
7.3
199
1303
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
2.6
7.3
51
201
F51.0
ICD-10 Finland
Nonorganic insomnia
1.4
7.2
333
2431
N03AX14
ATC
levetiracetam; systemic
2.3
7.2
61
265
H66.0
ICD-10 Finland
Acute suppurative otitis media
1.5
7.2
218
1456
S13.4
ICD-10 Finland
Sprain and strain of cervical spine
1.8
7.2
112
623
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
1.9
7.2
106
578
L02
ICPC
Back symptom/complaint
1.5
7.2
234
1590
R03AA01
ATC
epinephrine; inhalant
15.8
7.2
11
7
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.3
7.2
541
4275
B02.9
ICD-10 Finland
Zoster without complication
1.8
7.2
111
615
F01
ICPC
Eye pain
2.2
7.2
69
320
SPAT1283
SPAT
Restricted health certificate
1.3
7.2
569
4536
D64.9
ICD-10 Finland
Anaemia, unspecified
1.6
7.2
173
1098
E86
ICD-10 Finland
Volume depletion
2.8
7.2
42
149
A10BA02
ATC
metformin; oral
1.3
7.1
487
3797
C08CA13
ATC
lercanidipine; oral
1.5
7.1
218
1462
E66.8
ICD-10 Finland
Other obesity
1.7
7.1
132
777
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
1.8
7.1
110
611
M75.9
ICD-10 Finland
Shoulder lesion, unspecified
1.8
7.0
106
582
4939X
ICD-9 Finland
Asthma, unspecified[ASTHMA BRONCHIALE NUD]
2.6
7.0
49
191
M19.1
ICD-10 Finland
Post-traumatic arthrosis of other joints
2.4
7.0
54
225
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
1.4
7.0
281
1998
U01
ICPC
Dysuria/painful urination
1.6
7.0
190
1242
Y96.9
ICD-10 Finland
Unspecified type of accident
2.6
7.0
47
182
S60.2
ICD-10 Finland
Contusion of other parts of wrist and hand
1.8
7.0
117
667
F45.8
ICD-10 Finland
Other somatoform disorders
1.5
7.0
199
1316
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
2.2
7.0
64
288
L23.5
ICD-10 Finland
Allergic contact dermatitis due to other chemical products
3.5
7.0
30
86
N80.9
ICD-10 Finland
Endometriosis, unspecified
2.3
7.0
61
268
L03.1
ICD-10 Finland
Cellulitis of other parts of limb
2.3
7.0
61
268
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
2.0
6.9
85
433
D07XC01
ATC
betamethasone, combinations; topical
1.5
6.9
248
1725
A27
ICPC
Fear of other disease NOS
1.9
6.9
98
530
XX1XW
NOMESCO Finland
Extensive written report from radiologist
2.5
6.9
52
213
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
1.8
6.9
109
612
R32
ICD-10 Finland
Unspecified urinary incontinence
2.3
6.9
61
272
M54.3
ICD-10 Finland
Sciatica
1.7
6.9
125
732
A03FA02
ATC
cisapride; oral, rectal
1.6
6.9
157
981
M01AB55
ATC
diclofenac, combinations; oral
1.7
6.9
132
786
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
2.5
6.9
49
196
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.4
6.8
287
2058
G04CA02
ATC
tamsulosin; oral
1.5
6.8
269
1904
L01
ICPC
Neck symptom/complaint
1.4
6.8
331
2441
L30.0
ICD-10 Finland
Nummular dermatitis
2.2
6.8
68
319
R51
ICD-10 Finland
Headache
1.7
6.8
138
834
R51.81
ICD-10 Finland
Facial pain NOS
2.4
6.8
55
235
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.5
6.8
236
1628
A08
ICPC
Swelling
2.0
6.8
84
431
S80.0
ICD-10 Finland
Contusion of knee
1.6
6.8
158
995
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.5
6.8
257
1806
NE1AA
NOMESCO Finland
Pelvis X-ray examination
1.7
6.8
126
744
J02AC02
ATC
itraconazole; systemic
1.4
6.8
409
3128
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.4
6.8
282
2021
KH1AD
NOMESCO Finland
CT of urinary organs
2.1
6.8
68
321
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.4
6.8
326
2400
S02.20
ICD-10 Finland
Fracture of nasal bones, closed
2.6
6.7
45
174
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.6
6.7
176
1139
S04
ICPC
Lump/swelling localized
1.5
6.7
225
1540
SGC00
NOMESCO Finland
Local medication of root channels of tooth
1.4
6.7
262
1856
XW000
NOMESCO Finland
Bone marrow biopsy
2.0
6.7
79
398
L29
ICPC
Musculoskeletal sympt/complt other
1.6
6.7
165
1054
183
Kela drug reimbursment
Lamotrigin and topiramate
3.5
6.7
29
84
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
1.6
6.7
157
991
N07BA03
ATC
varenicline; oral
1.7
6.7
118
686
J04.0
ICD-10 Finland
Acute laryngitis
1.8
6.7
105
587
C09CA01
ATC
losartan; oral
1.3
6.7
431
3332
S71
ICPC
Herpes simplex
3.8
6.7
26
69
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.4
6.7
330
2443
K29.1
ICD-10 Finland
Other acute gastritis
3.0
6.7
35
117
L60.0
ICD-10 Finland
Ingrowing nail
1.8
6.6
105
589
R06.5
ICD-10 Finland
Mouth breathing
1.6
6.6
186
1224
K59.1
ICD-10 Finland
Functional diarrhoea
1.7
6.6
118
688
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
1.7
6.6
128
762
SPAT1312
SPAT
General health counselling
1.2
6.6
871
7394
Z01.7
ICD-10 Finland
Laboratory examination
1.5
6.6
241
1682
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
3.1
6.6
34
112
M13.9
ICD-10 Finland
Arthritis, unspecified
1.6
6.6
156
985
L08.8
ICD-10 Finland
Other specified local infections of skin and subcutaneous tissue
2.3
6.6
57
253
N05BA12
ATC
alprazolam; oral
1.5
6.5
229
1587
E87.5
ICD-10 Finland
Hyperkalaemia
3.3
6.5
30
91
UDQ12
NOMESCO Finland
Flexible laryngoscopy
1.7
6.5
115
669
K29
ICPC
Cardiovascular sympt/complt other
2.0
6.5
78
397
S70.0
ICD-10 Finland
Contusion of hip
2.1
6.5
66
313
H92.0
ICD-10 Finland
Otalgia
1.7
6.5
132
801
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
2.4
6.5
50
209
R69
ICD-10 Finland
Unknown and unspecified causes of morbidity
2.5
6.5
46
183
N71.0
ICD-10 Finland
Acute inflammatory disease of uterus
1.9
6.5
84
441
W10
ICD-10 Finland
Fall on and from stairs and steps
1.8
6.5
109
625
M54.6
ICD-10 Finland
Pain in thoracic spine
1.6
6.5
156
989
ACC51
NOMESCO Finland
Release of median nerve
1.6
6.4
161
1033
L51.8
ICD-10 Finland
Other erythema multiforme
70.0
6.4
7
*
D11AH05
ATC
dupilumab; topical
70.0
6.4
7
*
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
1.6
6.4
138
852
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
1.7
6.4
119
703
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
1.6
6.4
171
1113
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
2.0
6.4
81
420
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
2.9
6.4
37
130
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
1.6
6.3
142
885
N92.6
ICD-10 Finland
Irregular menstruation, unspecified
1.6
6.3
164
1059
N06AA10
ATC
nortriptyline; systemic
2.3
6.3
54
235
W79
ICD-10 Finland
Inhalation and ingestion of food causing obstruction of respiratory tract
8.2
6.3
13
16
A02BD02
ATC
lansoprazole, tetracycline and metronidazole; systemic
2.3
6.3
52
225
D01
ICPC
Abdominal pain/cramps general
1.4
6.3
288
2102
M10.9
ICD-10 Finland
Gout, unspecified
1.8
6.3
98
549
SPAT1310
SPAT
Counselling related to known health issue
1.2
6.3
804
6800
N73.9
ICD-10 Finland
Female pelvic inflammatory disease, unspecified
2.4
6.2
51
219
Z53.2
ICD-10 Finland
Procedure not carried out because of patient's decision for other and unspecified reasons
2.7
6.2
38
140
M48.0
ICD-10 Finland
Spinal stenosis
1.5
6.2
202
1376
H10.1
ICD-10 Finland
Acute atopic conjunctivitis
2.1
6.2
67
329
JAH01
NOMESCO Finland
Laparoscopy
1.7
6.2
117
696
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.2
6.2
946
8156
XG466
NOMESCO Finland
Sleep oxymetry
2.1
6.2
62
295
R30.0
ICD-10 Finland
Dysuria
1.9
6.1
87
471
G04BD12
ATC
mirabegron; oral
1.6
6.1
162
1054
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
1.6
6.1
133
820
A41.9
ICD-10 Finland
Sepsis, unspecified
2.1
6.1
64
310
R04.2
ICD-10 Finland
Haemoptysis
2.2
6.1
58
266
L08
ICPC
Shoulder symptom/complaint
1.3
6.1
396
3061
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.2
6.1
1053
9193
SBB20
NOMESCO Finland
Tooth X-ray examination in conjunction with visit to dentist
3.1
6.1
31
102
S01AA01
ATC
chloramphenicol; ophthalmic (antibiotics)
1.7
6.1
121
728
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
2.2
6.1
58
268
NGE10
NOMESCO Finland
Incision or suture of capsule of knee joint
3.6
6.1
25
70
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
1.5
6.1
190
1287
N80.3
ICD-10 Finland
Endometriosis of pelvic peritoneum
1.9
6.0
85
461
L02.9
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle, unspecified
2.0
6.0
68
339
M81.4
ICD-10 Finland
Drug-induced osteoporosis
6.7
6.0
14
21
X27
ICD-10 Finland
Contact with other specified venomous animals
10.0
6.0
11
11
R15
ICD-10 Finland
Faecal incontinence
2.2
6.0
55
249
SPAT1212
SPAT
Extensive examination of musculoskeletal system
1.5
6.0
185
1247
Z50.1
ICD-10 Finland
Other physical therapy
1.7
6.0
117
700

Mortality – FinRegistry

Association

Association between endpoint L12_URTICA_ALLERG and mortality.

Females

Parameter HR [95% CI] p-value
L12_URTICA_ALLERG 1.201 [1.06, 1.36] 0.004
Birth year 0.998 [0.99, 1.01] 0.694

During the follow-up period (1.1.1998 — 31.12.2019), 1258 out of 15742 females with L12_URTICA_ALLERG died.

Males

Parameter HR [95% CI] p-value
L12_URTICA_ALLERG 1.402 [1.22, 1.61] < 0.001
Birth year 0.988 [0.98, 1.0] 0.01

During the follow-up period (1.1.1998 — 31.12.2019), 791 out of 11004 males with L12_URTICA_ALLERG died.

Mortality risk

Mortality risk for people of age

years, who have L12_URTICA_ALLERG.

N-year risk Females Males
1 0.141% 0.233%
5 0.869% 1.554%
10 2.144% 4.065%
15 3.882% 7.337%
20 6.668% 12.586%

Relationships between endpoints

Index endpoint: L12_URTICA_ALLERG – Allergic urticaria

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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