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Injury of nerves and spinal cord at thorax level

ST19_INJURY_NERVES_SPINAL_CORD_THORAX_LEVEL

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 S24
  • Cause of death: ICD-10 S24

2 out of 7 registries used, show all original rules.

182

4. Check minimum number of events

None

182

5. Include endpoints

None

182

6. Filter based on genotype QC (FinnGen only)

182

Control definitions (FinnGen only)

Control exclude
ST19_INJURI_THORAX

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
S2
Name in latin
Laesiones nervorum regionis thoracis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 182 71 111
Unadjusted period prevalence (%) 0.04 0.02 0.05
Median age at first event (years) 50.03 47.14 51.88

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
166
Matched controls
1661
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
S24.0
ICD-10 Finland
Concussion and oedema of thoracic spinal cord
+∞
77.2
68
*
T91.3
ICD-10 Finland
Sequelae of injury of spinal cord
396.1
57.0
54
*
S22.0
ICD-10 Finland
Fracture of thoracic vertebra
742.4
56.0
52
*
NAJ22
NOMESCO Finland
Posterior reduction of fractrue of thoracic spine
+∞
47.1
43
*
XKD06
NOMESCO Finland
Physiologic investigation of micturition
39.1
39.8
50
18
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
107.8
38.9
41
5
G95.8
ICD-10 Finland
Other specified diseases of spinal cord
+∞
38.0
35
*
G82.2
ICD-10 Finland
Paraplegia, unspecified
+∞
35.7
33
*
S24.1
ICD-10 Finland
Other and unspecified injuries of thoracic spinal cord
+∞
32.3
30
*
S24.3
ICD-10 Finland
Injury of peripheral nerves of thorax
+∞
31.2
29
*
M03BX01
ATC
baclofen; systemic
81.6
30.2
33
5
L89
ICD-10 Finland
Decubitus ulcer and pressure area
65.4
28.3
32
6
S22.1
ICD-10 Finland
Multiple fractures of thoracic spine
+∞
26.8
25
*
XKC03
NOMESCO Finland
Water cystometry
26.6
26.1
36
17
X59
ICD-10 Finland
Exposure to unspecified factor
6.9
24.8
74
173
N03AX16
ATC
pregabalin; oral
6.2
23.5
79
213
N31.9
ICD-10 Finland
Neuromuscular dysfunction of bladder, unspecified
132.5
22.2
23
*
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
13.4
21.9
39
37
S22.4
ICD-10 Finland
Multiple fractures of ribs
238.6
21.1
21
*
S24.2
ICD-10 Finland
Injury of nerve root of thoracic spine
+∞
20.2
19
*
T91.1
ICD-10 Finland
Sequelae of fracture of spine
225.7
20.0
20
*
JN5BD
NOMESCO Finland
Head and body CT examination for trauma
53.0
19.8
23
5
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
6.7
19.4
55
114
ZXE20
NOMESCO Finland
More than three and less than five hours
7.2
18.7
49
91
R4110
NOMESCO Finland
Physiotherapy
4.9
17.9
73
230
XKD03
NOMESCO Finland
Urethral pressure profilometry
26.4
17.0
23
10
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
6.7
16.5
45
87
ZXD05
NOMESCO Finland
Urgent procedure
4.3
16.4
83
315
N31.2
ICD-10 Finland
Flaccid neuropathic bladder, not elsewhere classified
37.5
16.1
20
6
S32.0
ICD-10 Finland
Fracture of lumbar vertebra
25.1
16.0
22
10
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
8.5
16.0
36
52
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
5.7
16.0
51
120
W17
ICD-10 Finland
Other fall from one level to another
12.3
16.0
29
28
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
4.4
15.8
72
248
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
6.1
15.3
45
95
G82.1
ICD-10 Finland
Spastic paraplegia
+∞
14.8
14
*
N81
ICPC
Injury nervous system other
163.7
14.7
15
*
Z3226
NOMESCO Finland
Physiotherapist
4.8
14.4
55
156
A28
ICPC
Limited function/disability NOS
6.6
14.4
39
74
N18
ICPC
Paralysis/weakness
22.5
14.2
20
10
J01EA01
ATC
trimethoprim; systemic
4.5
14.1
57
171
S24.6
ICD-10 Finland
Injury of unspecified nerve of thorax
+∞
13.7
13
*
T90.5
ICD-10 Finland
Sequelae of intracranial injury
23.6
13.7
19
9
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
5.9
13.5
40
85
KCV12
NOMESCO Finland
Urinary bladder endoscopic botulin therapy
44.0
13.4
16
*
V49.9
ICD-10 Finland
Car occupant [any] injured in unspecified traffic accident
11.1
13.3
25
26
X58
ICD-10 Finland
Exposure to other specified factors
4.6
13.0
50
142
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
7.2
12.9
32
53
SPAT1262
SPAT
Handing over of treatment supplies
4.5
12.9
52
154
TKC20
NOMESCO Finland
Catheterisation of bladder
7.7
12.8
30
46
QBG10
NOMESCO Finland
Excision and repair of bedsore of trunk
+∞
12.7
12
*
S22.3
ICD-10 Finland
Fracture of rib
13.2
12.2
21
18
N02AX02
ATC
tramadol; systemic, rectal
3.3
12.1
89
429
WX408
NOMESCO Finland
General anesthesy, balanced
3.6
11.9
65
249
QBB05
NOMESCO Finland
Revision of wound of skin of trunk
70.0
11.8
13
*
N31.8
ICD-10 Finland
Other neuromuscular dysfunction of bladder
70.0
11.8
13
*
G82.0
ICD-10 Finland
Flaccid paraplegia
128.5
11.6
12
*
SPAT1148
SPAT
Treatment of chronic ulcer or burn
5.0
11.5
39
96
Z3231
NOMESCO Finland
Registered nurse
3.5
11.4
64
250
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
12.5
11.4
20
18
W19
ICD-10 Finland
Unspecified fall
5.6
11.0
33
70
N30.0
ICD-10 Finland
Acute cystitis
5.1
11.0
36
85
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
4.7
10.9
39
101
ZXE10
NOMESCO Finland
More than one and less than three hours
3.2
10.8
78
364
L28
ICPC
Limited function/disability (L)
4.9
10.8
37
92
R1250
NOMESCO Finland
Evaluation of functional capability
15.6
10.7
17
12
Z3229
NOMESCO Finland
Other healthcare associate professional
6.6
10.5
27
47
NAG53
NOMESCO Finland
Posterior or lateral fusion of thoracic spine with fixation, more than 3 vertebraea
+∞
10.5
10
*
S27.0
ICD-10 Finland
Traumatic pneumothorax
+∞
10.5
10
*
N31.1
ICD-10 Finland
Reflex neuropathic bladder, not elsewhere classified
35.0
10.5
13
*
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
11.7
10.1
18
17
AA1AD
NOMESCO Finland
CT of head and brain
3.7
10.0
49
169
R4120
NOMESCO Finland
Occupational therapy
6.8
10.0
25
42
ZZH40
NOMESCO Finland
Substitute of bone
28.0
10.0
13
5
J01MA02
ATC
ciprofloxacin; systemic
3.0
9.9
83
419
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
4.7
9.7
34
86
R33
ICD-10 Finland
Retention of urine
5.4
9.6
29
62
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
8.6
9.5
20
26
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
5.1
9.3
30
69
Z2446
NOMESCO Finland
Social worker
7.3
9.3
22
34
N02BE01
ATC
paracetamol; systemic, rectal
4.3
9.2
151
1162
V29.9
ICD-10 Finland
Motorcycle rider [any] injured in unspecified traffic accident
20.0
9.1
13
7
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
13.6
9.1
15
12
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
4.1
9.0
37
109
S97
ICPC
Chronic ulcer skin
6.9
9.0
22
36
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
5.1
8.9
28
63
WX402
NOMESCO Finland
General anaesthesia
3.4
8.8
47
171
TPH04
NOMESCO Finland
Cathetrisation of vein
3.5
8.8
46
164
NA2AD
NOMESCO Finland
Thoracic spine CT examination
52.8
8.8
10
*
N02AA05
ATC
oxycodone; systemic
4.2
8.7
34
96
S12.2
ICD-10 Finland
Fracture of other specified cervical vertebra
21.4
8.6
12
6
Y94.8
ICD-10 Finland
Other leisure activity accident
13.8
8.5
14
11
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
6.0
8.5
23
43
S14.0
ICD-10 Finland
Concussion and oedema of cervical spinal cord
94.6
8.5
9
*
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
15.5
8.3
13
9
KA1AE
NOMESCO Finland
Kidney ultrasound examination
12.6
8.2
14
12
N06AX21
ATC
duloxetine; oral
4.1
8.2
33
95
JN4BD
NOMESCO Finland
Extensive body CT
4.5
8.0
28
71
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.7
8.0
70
352
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.8
7.9
60
276
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
4.5
7.9
28
72
T88.8
ICD-10 Finland
Other specified complications of surgical and medical care, not elsewhere classified
47.2
7.8
9
*
UKC02
NOMESCO Finland
Cystoscopy
3.4
7.7
41
146
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
5.0
7.6
24
54
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
8.3
7.6
16
21
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.6
7.5
76
410
NAJ32
NOMESCO Finland
Posterior reduction of fractrue of lumbar spine
83.6
7.5
8
*
QBG00
NOMESCO Finland
Debridement of bedsore of trunk
83.6
7.5
8
*
C03CA01
ATC
furosemide; systemic
3.1
7.4
44
171
SPAT1254
SPAT
Administration of medicine
3.8
7.4
32
99
S24.5
ICD-10 Finland
Injury of other nerves of thorax
+∞
7.3
7
*
ABD40
NOMESCO Finland
Implantation of spinal injection device
+∞
7.3
7
*
G82.5
ICD-10 Finland
Tetraplegia, unspecified
+∞
7.3
7
*
S27.1
ICD-10 Finland
Traumatic haemothorax
+∞
7.3
7
*
S22.2
ICD-10 Finland
Fracture of sternum
+∞
7.3
7
*
N32.82
ICD-10 Finland
Instability of the detrusor vesicae muscle
16.7
7.3
11
7
W11
ICD-10 Finland
Fall on and from ladder
16.7
7.3
11
7
U05
ICPC
Urination problems other
6.2
7.3
19
34
NE1AA
NOMESCO Finland
Pelvis X-ray examination
6.6
7.3
18
30
WX404
NOMESCO Finland
Intravenous generell anesthesy
3.0
7.2
46
187
S06.2
ICD-10 Finland
Diffuse brain injury
31.5
7.2
9
*
ZXD35
NOMESCO Finland
Usual procedure
9.4
7.2
14
16
U07
ICPC
Urine symptom/complaint other
6.2
7.0
18
32
N06AX16
ATC
venlafaxine; oral
3.2
7.0
38
139
U29
ICPC
Urinary symptom/complaint other
8.9
7.0
14
17
N03AX12
ATC
gabapentin; oral
3.1
6.9
41
157
SPAT1229
SPAT
Assessment of need for aid
4.8
6.9
22
51
ZXE30
NOMESCO Finland
More than five and less than seven hours
6.0
6.8
18
33
V48.9
ICD-10 Finland
Car occupant injured in noncollision transport accident, unspecified car occupant injured in traffic accident
41.8
6.8
8
*
TPH07
NOMESCO Finland
Cathetrisation of artery
4.5
6.7
23
57
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
4.3
6.6
24
63
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.5
6.6
31
102
G95.0
ICD-10 Finland
Syringomyelia and syringobulbia
72.5
6.5
7
*
V89
ICD-10 Finland
Motor- or nonmotor-vehicle accident, type of vehicle unspecified
72.5
6.5
7
*
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
18.9
6.3
9
5
WX725
NOMESCO Finland
Noninvasive ventilation
6.2
6.3
16
28
RS221
NOMESCO Finland
NA
27.8
6.3
8
*
A82
ICPC
Secondary effect of trauma
+∞
6.3
6
*
S24.4
ICD-10 Finland
Injury of thoracic sympathetic nerves
+∞
6.3
6
*
S27.3
ICD-10 Finland
Other injuries of lung
+∞
6.3
6
*
Z2445
NOMESCO Finland
Psychologist
8.2
6.3
13
17
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
5.0
6.2
19
42
WX882
NOMESCO Finland
High dependency care
9.1
6.2
12
14
ZZH21
NOMESCO Finland
Graft of patients own bone, small pieces
13.2
6.2
10
8
K59.00
ICD-10 Finland
Constipation caused by slow bowel passage (SCT)
13.2
6.2
10
8
S82.1
ICD-10 Finland
Fracture of upper end of tibia
10.6
6.1
11
11
Z71.8
ICD-10 Finland
Other specified counselling
2.6
6.1
51
245
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
7.7
6.0
13
18
SPAT1222
SPAT
Counselling/guidance promoting independent living
3.3
6.0
30
104

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: ST19_INJURY_NERVES_SPINAL_CORD_THORAX_LEVEL – Injury of nerves and spinal cord at thorax level

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).