Other diseases of spinal cord

G6_SPINOTH

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 G95
  • Hospital discharge: ICD-9 336
  • Hospital discharge: ICD-8 349
  • Cause of death: ICD-10 G95
  • Cause of death: ICD-9 336
  • Cause of death: ICD-8 349

2 out of 7 registries used, show all original rules.

1122

4. Check minimum number of events

None

1122

5. Include endpoints

None

1122

6. Filter based on genotype QC (FinnGen only)

1122

Control definitions (FinnGen only)

Control exclude
G6_OTHNEU

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
G90-G99

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 9073 4166 4815
Only index persons 7450 3565 3885
Unadjusted period prevalence (%)
Whole population 0.13 0.12 0.13
Only index persons 0.14 0.13 0.15
Median age at first event (years)
Whole population 53.28 52.68 53.64
Only index persons 51.72 51.16 52.23

-FinnGen-

Key figures

All Female Male
Number of individuals 1122 570 552
Unadjusted period prevalence (%) 0.22 0.19 0.24
Median age at first event (years) 52.44 48.84 56.16

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1009
Matched controls
10088
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G95.8
ICD-10 Finland
Other specified diseases of spinal cord
+∞
323.0
371
*
G95.0
ICD-10 Finland
Syringomyelia and syringobulbia
3334.3
287.6
264
*
XKC03
NOMESCO Finland
Water cystometry
32.4
200.4
269
112
G95.9
ICD-10 Finland
Disease of spinal cord, unspecified
+∞
181.9
169
*
M03BX01
ATC
baclofen; systemic
50.2
156.6
189
46
T91.3
ICD-10 Finland
Sequelae of injury of spinal cord
573.6
153.0
148
*
XKD06
NOMESCO Finland
Physiologic investigation of micturition
23.2
150.8
223
122
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
12.3
133.3
258
273
G82.2
ICD-10 Finland
Paraplegia, unspecified
174.2
105.5
109
7
N03AX16
ATC
pregabalin; oral
4.9
103.0
430
1321
N03AX12
ATC
gabapentin; oral
5.8
101.4
337
797
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
11.8
96.2
187
191
XKD03
NOMESCO Finland
Urethral pressure profilometry
21.5
93.3
140
75
G95.2
ICD-10 Finland
Cord compression, unspecified
+∞
92.1
87
*
UKC02
NOMESCO Finland
Cystoscopy
5.2
91.0
341
909
N31.9
ICD-10 Finland
Neuromuscular dysfunction of bladder, unspecified
71.5
90.5
103
16
N18
ICPC
Paralysis/weakness
29.3
89.5
122
47
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
43.9
88.9
110
28
L89
ICD-10 Finland
Decubitus ulcer and pressure area
30.2
87.3
118
44
G95.1
ICD-10 Finland
Vascular myelopathies
+∞
86.7
82
*
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
38.5
79.4
101
29
TKC20
NOMESCO Finland
Catheterisation of bladder
7.5
77.6
199
321
N31.2
ICD-10 Finland
Flaccid neuropathic bladder, not elsewhere classified
37.7
77.5
99
29
J01EA01
ATC
trimethoprim; systemic
3.9
75.8
402
1455
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
7.4
74.6
192
310
R1250
NOMESCO Finland
Evaluation of functional capability
20.4
74.3
113
62
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
17.0
70.2
114
75
G35
ICD-10 Finland
Multiple sclerosis
22.8
67.7
99
48
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
4.8
67.4
260
685
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
19.6
67.0
103
58
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
11.4
66.8
130
129
N31.1
ICD-10 Finland
Reflex neuropathic bladder, not elsewhere classified
64.0
66.6
77
13
SPAT1229
SPAT
Assessment of need for aid
6.7
65.7
182
323
KCV12
NOMESCO Finland
Urinary bladder endoscopic botulin therapy
39.5
61.0
77
21
SPAT1262
SPAT
Handing over of treatment supplies
3.7
57.6
307
1069
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
4.3
57.6
243
688
R33
ICD-10 Finland
Retention of urine
5.7
57.4
179
366
N31.8
ICD-10 Finland
Other neuromuscular dysfunction of bladder
73.2
54.8
62
9
S14.0
ICD-10 Finland
Concussion and oedema of cervical spinal cord
189.9
52.4
54
*
N03AE01
ATC
clonazepam; systemic
6.6
51.9
143
248
109
Kela drug reimbursment
Multiple sclerosis
24.1
51.8
74
33
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.9
50.5
236
725
G82.1
ICD-10 Finland
Spastic paraplegia
+∞
50.4
48
*
J01MA02
ATC
ciprofloxacin; systemic
2.8
50.1
498
2622
NA2CG
NOMESCO Finland
Thoracal spine extensive MRI examination with high intensity magnet
25.8
50.0
70
29
G04BD12
ATC
mirabegron; oral
4.8
50.0
184
449
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
4.3
49.8
205
560
L28
ICPC
Limited function/disability (L)
3.8
48.9
244
790
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
29.9
46.2
62
22
303
Kela drug reimbursment
Dimethyl fumarate, interferon beta, glatiramer acetate and teriflunomid (Multiple sclerosis)
27.9
46.1
63
24
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
5.3
45.9
151
324
WX408
NOMESCO Finland
General anesthesy, balanced
2.9
45.8
372
1704
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
4.5
45.8
179
462
G04BD08
ATC
solifenacin; oral
5.6
45.4
141
283
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
3.5
45.3
245
842
34999
ICD-8 Finland
Other diseases of spinal cord, Other and unspecified
+∞
45.1
43
*
AA1AD
NOMESCO Finland
CT of head and brain
3.2
44.7
292
1151
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
3.4
44.1
249
882
A28
ICPC
Limited function/disability NOS
3.7
44.1
218
695
R4120
NOMESCO Finland
Occupational therapy
5.8
43.4
131
253
N31.0
ICD-10 Finland
Uninhibited neuropathic bladder, not elsewhere classified
156.8
43.1
45
*
N30.0
ICD-10 Finland
Acute cystitis
3.7
42.8
212
675
N06AX21
ATC
duloxetine; oral
4.2
42.7
179
492
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
9.7
42.2
88
98
XKD00
NOMESCO Finland
Uroflowmetry
3.2
41.6
256
961
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
5.5
40.8
128
259
KA1AE
NOMESCO Finland
Kidney ultrasound examination
9.7
39.9
83
92
S24.0
ICD-10 Finland
Concussion and oedema of thoracic spinal cord
+∞
39.8
38
*
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
11.3
39.2
75
71
G82.5
ICD-10 Finland
Tetraplegia, unspecified
89.8
39.1
43
5
Q07.0
ICD-10 Finland
Arnold-Chiari syndrome
109.4
39.0
42
*
SPAT1148
SPAT
Treatment of chronic ulcer or burn
3.5
39.0
209
702
M48.0
ICD-10 Finland
Spinal stenosis
3.7
38.4
185
571
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
4.2
37.8
157
425
ABC60
NOMESCO Finland
Decompression of cervical spinal cord
35.9
37.5
48
14
G99.2*M47.1
ICD-10 Finland
Spondylogenic compression of spinal cord
380.7
37.3
37
*
T91.1
ICD-10 Finland
Sequelae of fracture of spine
104.0
37.0
40
*
S97
ICPC
Chronic ulcer skin
5.6
37.0
114
225
N86
ICPC
Multiple sclerosis
31.4
36.4
48
16
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
4.6
36.2
133
319
N32.83
ICD-10 Finland
Nozzle synergy in the bladder neck
101.3
36.0
39
*
NA7BG
NOMESCO Finland
Spine and spinal cord MRI examination with high intensity magnet
39.2
35.9
45
12
N32.82
ICD-10 Finland
Instability of the detrusor vesicae muscle
13.7
35.5
62
48
ZXE20
NOMESCO Finland
More than three and less than five hours
3.3
35.5
209
750
A06AD11
ATC
lactulose; oral
3.3
35.5
203
712
ZXD05
NOMESCO Finland
Urgent procedure
2.5
35.2
386
2031
157
Kela drug reimbursment
Dimethyl fumarate, glatiramer acetate, interferon beta and teriflunomid (Multiple sclerosis)
21.0
35.1
52
26
N28
ICPC
Limited function/disability (N)
16.4
34.6
56
36
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
7.2
34.6
87
131
N81
ICPC
Injury nervous system other
59.4
34.4
40
7
G99.2
ICD-10 Finland
Myelopathy in diseases classified elsewhere
+∞
33.5
32
*
G04BD07
ATC
tolterodine; oral
5.9
33.5
98
181
S22.0
ICD-10 Finland
Fracture of thoracic vertebra
12.7
33.3
60
50
N99
ICPC
Neurological disease other
18.1
32.2
50
29
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
3.3
31.9
182
636
M03BX02
ATC
tizanidine; oral
2.2
31.9
656
4584
L03AB07
ATC
interferon beta-1a; parenteral
28.0
31.7
43
16
N02AA05
ATC
oxycodone; systemic
3.1
31.5
197
734
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
4.2
30.7
126
335
M49.4*G95.0
ICD-10 Finland
Neuropathic spondylopathy in syringomyelia and syringobulbia
+∞
30.4
29
*
S12.2
ICD-10 Finland
Fracture of other specified cervical vertebra
18.2
30.3
47
27
SPAT1167
SPAT
Insertion of urinary catheter
7.1
30.3
76
114
G04BD04
ATC
oxybutynin; oral, transdermal
5.0
30.0
102
224
SPAT1215
SPAT
Assessment of need for medical rehabilitation
6.0
30.0
86
155
G82.0
ICD-10 Finland
Flaccid paraplegia
311.2
30.0
30
*
U05
ICPC
Urination problems other
5.6
29.9
91
176
NAJ22
NOMESCO Finland
Posterior reduction of fractrue of thoracic spine
85.3
29.9
33
*
N02AX02
ATC
tramadol; systemic, rectal
2.2
29.4
470
2893
J01CA08
ATC
pivmecillinam; oral
2.2
29.0
415
2425
TKC10
NOMESCO Finland
Percutaneous puncture of bladder
11.1
28.8
55
52
TKC22
NOMESCO Finland
Catheterisation instruction
8.5
28.7
64
80
SPAT1231
SPAT
Assessment of adjustments needed in living environment
10.5
28.5
56
56
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.3
28.4
340
1821
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
5.9
28.2
82
150
J01MA12
ATC
levofloxacin; systemic
2.6
27.9
247
1129
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
2.9
27.9
195
775
TPH04
NOMESCO Finland
Cathetrisation of vein
2.5
27.5
259
1228
SPAT1301
SPAT
No procedures
2.2
27.5
361
2015
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.8
27.2
202
836
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
5.6
27.0
81
154
U07
ICPC
Urine symptom/complaint other
4.4
26.6
101
248
G97.0
ICD-10 Finland
Cerebrospinal fluid leak from spinal puncture
+∞
26.2
25
*
L03AX13
ATC
glatiramer acetate; parenteral
31.9
26.0
34
11
TAB00
NOMESCO Finland
Lumbar puncture
5.4
26.0
81
161
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.5
26.0
129
402
R4110
NOMESCO Finland
Physiotherapy
2.3
25.9
301
1578
QBG10
NOMESCO Finland
Excision and repair of bedsore of trunk
95.9
25.8
28
*
M47.1
ICD-10 Finland
Other spondylosis with myelopathy
13.9
25.7
44
33
R20.2
ICD-10 Finland
Paraesthesia of skin
4.0
25.4
106
285
3369X
ICD-9 Finland
Other diseases of spinal cord, Unspecified disease of spinal cord
+∞
25.1
24
*
J01XE01
ATC
nitrofurantoin; oral
8.8
24.6
53
63
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.2
24.3
326
1818
SPAT1263
SPAT
Sampling
2.0
24.2
451
2884
S32.0
ICD-10 Finland
Fracture of lumbar vertebra
6.4
24.0
64
105
U13
ICPC
Bladder symptom/complaint other
6.1
23.9
67
117
TPH07
NOMESCO Finland
Cathetrisation of artery
3.1
23.9
144
517
ABE50
NOMESCO Finland
Occipitocervical decompression
128.0
23.7
25
*
N30.9
ICD-10 Finland
Cystitis, unspecified
4.4
23.2
87
211
NA1AD
NOMESCO Finland
Cervical spine CT examination
5.3
23.2
72
143
X59
ICD-10 Finland
Exposure to unspecified factor
2.4
23.1
223
1057
ABB20
NOMESCO Finland
Drainage of intra- or extramedullary cyst of spinal canal
+∞
23.0
22
*
9072A
ICD-9 Finland
Late effects of injuries to the nervous system, Late effect of spinal cord injury
+∞
23.0
22
*
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
4.0
22.9
97
264
K59.09
ICD-10 Finland
Constipation, unspecified
4.0
22.8
96
260
G99.2*M47.9
ICD-10 Finland
Myelopathy in spondylosis
235.0
22.7
23
*
ABD40
NOMESCO Finland
Implantation of spinal injection device
235.0
22.7
23
*
WX402
NOMESCO Finland
General anaesthesia
2.5
22.5
203
926
ABB00
NOMESCO Finland
Excision of lesion of spinal canal
46.1
22.4
27
6
K59.0
ICD-10 Finland
Constipation
4.0
22.2
92
246
W17
ICD-10 Finland
Other fall from one level to another
4.6
22.1
79
183
J01XX05
ATC
methenamine; oral
16.4
22.0
35
22
WX704
NOMESCO Finland
Intubation
3.5
22.0
110
344
G99.2*M50.0
ICD-10 Finland
Cervical disc disorder with myelopathy
+∞
21.9
21
*
J01MA06
ATC
norfloxacin; oral
2.7
21.8
170
714
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
9.7
21.7
44
47
W19
ICD-10 Finland
Unspecified fall
3.1
21.6
128
453
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
5.5
21.5
65
125
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
7.5
21.5
51
71
QBB05
NOMESCO Finland
Revision of wound of skin of trunk
12.3
21.2
38
32
U04
ICPC
Incontinence urine
4.6
21.1
76
177
G04AC01
ATC
NA
6.0
21.1
59
103
204
Kela drug reimbursment
Leukemia lymphatica
5.4
21.1
65
128
R15
ICD-10 Finland
Faecal incontinence
6.4
21.0
56
92
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.9
20.9
139
530
N06AX16
ATC
venlafaxine; oral
2.6
20.6
166
708
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
14.0
20.1
34
25
SPAT1216
SPAT
Assessment of functional ability
2.5
19.7
170
755
U29
ICPC
Urinary symptom/complaint other
5.6
19.6
58
109
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.5
19.6
169
751
N06AA09
ATC
amitriptyline; systemic
2.9
19.5
128
483
N03AX09
ATC
lamotrigine; oral
4.3
19.3
74
184
N02BE01
ATC
paracetamol; systemic, rectal
2.2
19.2
853
7238
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.2
19.1
104
346
ABD30
NOMESCO Finland
Implantation of spinal stimulation device
20.5
19.1
28
14
G83.4
ICD-10 Finland
Cauda equina syndrome
20.5
19.1
28
14
KCW98
NOMESCO Finland
Other transluminal endoscopic operation on bladder
56.1
19.0
22
*
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.7
19.0
145
600
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
+∞
18.8
18
*
G04BE03
ATC
sildenafil; oral
8.8
18.8
40
47
G45.1
ICD-10 Finland
Carotid artery syndrome (hemispheric)
193.4
18.6
19
*
G04CA02
ATC
tamsulosin; oral
2.1
18.5
249
1360
M47.9
ICD-10 Finland
Spondylosis, unspecified
5.6
18.5
54
100
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
4.1
18.4
73
187
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.5
18.4
160
712
H01BA02
ATC
desmopressin; nasal, systemic, sublingual
8.5
18.3
40
49
ABD32
NOMESCO Finland
Implantation of temporary spinal stimulation device
25.6
18.3
25
10
K59.00
ICD-10 Finland
Constipation caused by slow bowel passage (SCT)
6.6
18.3
47
74
R39.1
ICD-10 Finland
Other difficulties with micturition
5.1
18.2
58
119
QBG00
NOMESCO Finland
Debridement of bedsore of trunk
53.5
18.0
21
*
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.7
18.0
134
547
R51.80
ICD-10 Finland
Headache
2.5
17.9
156
695
308
Kela drug reimbursment
Alprostadil, sildenafil and combination product containing aviptadil and phentolamine
6.8
17.8
45
69
S14.1
ICD-10 Finland
Other and unspecified injuries of cervical spinal cord
+∞
17.8
17
*
34998
ICD-8 Finland
Other diseases of spinal cord, Alii definiti
+∞
17.8
17
*
3360A
ICD-9 Finland
Other diseases of spinal cord, Syringomyelia and syringobulbia
+∞
17.8
17
*
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.7
17.8
132
537
Z01.8
ICD-10 Finland
Other specified special examinations
2.1
17.6
232
1253
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
6.3
17.6
47
78
H46
ICD-10 Finland
Optic neuritis
14.2
17.3
29
21
NAJ32
NOMESCO Finland
Posterior reduction of fractrue of lumbar spine
42.8
17.3
21
5
Z3226
NOMESCO Finland
Physiotherapist
2.2
17.3
206
1067
N05BA01
ATC
diazepam; systemic, rectal
2.4
17.3
153
687
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
2.4
17.3
162
748
WX725
NOMESCO Finland
Noninvasive ventilation
4.0
17.2
71
189
NA1CM
NOMESCO Finland
Cervical spine extensive MRI examination with 3 Tesla magnet
50.9
17.0
20
*
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
3.7
17.0
75
212
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.1
17.0
96
328
ZXE10
NOMESCO Finland
More than one and less than three hours
1.8
16.9
370
2414
G04BD09
ATC
trospium; oral
6.0
16.8
46
79
Z3229
NOMESCO Finland
Other healthcare associate professional
2.9
16.7
108
403
R26.8
ICD-10 Finland
Other and unspecified abnormalities of gait and mobility
7.0
16.6
41
61
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
4.0
16.6
68
180
N04BB01
ATC
amantadine; oral
7.7
16.5
38
51
N39.4
ICD-10 Finland
Other specified urinary incontinence
3.1
16.5
95
329
L86
ICPC
Back syndrome with radiating pain
3.5
16.4
78
234
TQW11
NOMESCO Finland
Vacuum treatment of wound
7.0
16.3
40
59
JN5BD
NOMESCO Finland
Head and body CT examination for trauma
15.7
16.2
26
17
R52.2
ICD-10 Finland
Other chronic pain
4.9
15.9
52
110
Z3231
NOMESCO Finland
Registered nurse
1.9
15.9
285
1729
NAJ10
NOMESCO Finland
Anterior reduction of fracture of cervical spine
61.0
15.8
18
*
NAG53
NOMESCO Finland
Posterior or lateral fusion of thoracic spine with fixation, more than 3 vertebraea
61.0
15.8
18
*
NA1DG
NOMESCO Finland
Cervical spine very extensive MRI examination with high intensity magnet
34.0
15.8
20
6
A06AC01
ATC
ispaghula (psylla seeds); oral
2.0
15.7
246
1419
G45.0
ICD-10 Finland
Vertebro-basilar artery syndrome
+∞
15.7
15
*
Z43.5
ICD-10 Finland
Attention to cystostomy
19.6
15.6
23
12
G37.9
ICD-10 Finland
Demyelinating disease of central nervous system, unspecified
14.0
15.6
26
19
G82.4
ICD-10 Finland
Spastic tetraplegia
162.4
15.5
16
*
SPAT1260
SPAT
Consultation of another employee
2.1
15.5
199
1059
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
3.6
15.5
70
202
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.0
15.4
217
1200
L03AB08
ATC
interferon beta-1b; parenteral
38.7
15.4
19
5
R31
ICD-10 Finland
Unspecified haematuria
2.6
15.4
115
469
N12
ICD-10 Finland
Tubulo-interstitial nephritis, not specified as acute or chronic
7.7
15.3
35
47
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.8
15.2
348
2289
V49.9
ICD-10 Finland
Car occupant [any] injured in unspecified traffic accident
4.2
15.1
58
145
M54.1
ICD-10 Finland
Radiculopathy
4.2
14.9
57
142
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
8.1
14.9
33
42
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.8
14.9
98
370
AWB00
NOMESCO Finland
Reoperation for superficial infection in surgery of the nervous system
57.5
14.8
17
*
ABB10
NOMESCO Finland
Resection of lesion of spinal canal
57.5
14.8
17
*
N05CF01
ATC
zopiclone; oral
1.8
14.7
318
2046
J01FF01
ATC
clindamycin; systemic
1.9
14.7
275
1687
L17
ICPC
Foot/toe symptom/complaint
1.9
14.7
261
1573
M54.4
ICD-10 Finland
Lumbago with sciatica
2.1
14.6
173
887
C03CA01
ATC
furosemide; systemic
1.9
14.6
268
1632
NAG40
NOMESCO Finland
Anterior fusion of cervical spine without fixation
5.8
14.3
40
71
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.8
14.3
98
379
D32.1
ICD-10 Finland
Benign neoplasm: Spinal meninges
43.1
14.1
17
*
G04AA01
ATC
NA
12.2
14.1
25
21
U71
ICPC
Cystitis/urinary infection other
3.2
14.1
75
246
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
4.5
14.1
50
116
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.9
14.1
86
310
M54.5
ICD-10 Finland
Low back pain
1.8
14.1
318
2069
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.8
14.1
298
1900
WX110
NOMESCO Finland
Local anesthesy
1.7
14.0
664
5360
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
3.2
14.0
74
242
U02
ICPC
Urinary frequency/urgency
2.3
14.0
137
645
A02BC02
ATC
pantoprazole; systemic
1.7
13.9
613
4844
SPAT1295
SPAT
Other function in accordance with physical therapy nomenclature
3.4
13.9
69
215
ABD99
NOMESCO Finland
Other operation on spinal cord or nerve for pain or impaired function
30.5
13.9
18
6
A46
ICD-10 Finland
Erysipelas
2.2
13.9
154
768
N29
ICPC
Neurological sympt/complt other
6.2
13.9
37
62
A41.9
ICD-10 Finland
Sepsis, unspecified
4.0
13.8
55
143
ABC56
NOMESCO Finland
Decompression of lumbar spinal canal and nerve roots
5.4
13.7
41
79
N03AF02
ATC
oxcarbazepine; oral
4.5
13.7
48
110
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
13.6
414
2942
ABB40
NOMESCO Finland
Evacuation of spontaneous haematoma of spinal canal
+∞
13.6
13
*
S18
ICPC
Laceration/cut
1.7
13.6
399
2808
M54.2
ICD-10 Finland
Cervicalgia
2.9
13.5
83
300
J01DB01
ATC
cefalexin; oral
1.8
13.5
794
6792
Q05.2
ICD-10 Finland
Lumbar spina bifida with hydrocephalus
141.8
13.5
14
*
A01
ICPC
Pain general/multiple sites
2.8
13.5
91
350
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.9
13.3
242
1462
XA800
NOMESCO Finland
Neuropsychological investigation
3.6
13.2
59
169
N45.9
ICD-10 Finland
Orchitis, epididymitis and epididymo-orchitis without abscess
6.4
13.1
34
55
3400A
ICD-9 Finland
Multiple sclerosis[SCLEROSIS MULTIPLEX (DISSEMINATA)]
28.8
13.0
17
6
NAU20
NOMESCO Finland
Removal of internal fixation device from spine or neck
28.8
13.0
17
6
S22.1
ICD-10 Finland
Multiple fractures of thoracic spine
22.9
12.9
18
8
S12.7
ICD-10 Finland
Multiple fractures of cervical spine
22.9
12.9
18
8
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
3.6
12.7
57
165
D43.4
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Spinal cord
+∞
12.5
12
*
G91.9
ICD-10 Finland
Hydrocephalus, unspecified
+∞
12.5
12
*
G91.2
ICD-10 Finland
Normal-pressure hydrocephalus
+∞
12.5
12
*
G93.0
ICD-10 Finland
Cerebral cysts
+∞
12.5
12
*
ABE40
NOMESCO Finland
Operation for hydromyelia
+∞
12.5
12
*
NA2DG
NOMESCO Finland
Thoracal spine very extensive MRI examination with high intensity magnet
24.6
12.5
17
7
G04BD11
ATC
fesoterodine; oral
4.3
12.4
46
112
J01DA01
ATC
[U] cefalexin; systemic
1.6
12.3
596
4753
N06AA10
ATC
nortriptyline; systemic
5.2
12.2
37
73
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
3.1
12.1
66
221
R5140
NOMESCO Finland
Monitoring the use of the aid
2.3
12.1
119
557
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.9
12.1
75
274
Y83.9
ICD-10 Finland
Surgical procedure, unspecified as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
4.3
12.0
44
106
SPAT1310
SPAT
Counselling related to known health issue
1.7
12.0
303
2022
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.1
11.9
140
713
T90.5
ICD-10 Finland
Sequelae of intracranial injury
8.5
11.8
25
30
X58
ICD-10 Finland
Exposure to other specified factors
2.1
11.8
140
717
NE1AA
NOMESCO Finland
Pelvis X-ray examination
2.8
11.8
77
290
KCE02
NOMESCO Finland
Transluminal endoscopic extraction of calculus from bladder
10.7
11.8
22
21
Z50.1
ICD-10 Finland
Other physical therapy
3.1
11.7
63
209
N21.0
ICD-10 Finland
Calculus in bladder
7.8
11.7
26
34
Z73.3
ICD-10 Finland
Stress, not elsewhere classified
7.8
11.7
26
34
L04AA31
ATC
teriflunomide; oral
23.2
11.6
16
7
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.2
11.6
125
614
Z2446
NOMESCO Finland
Social worker
2.8
11.6
76
288
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.9
11.5
71
258
AA7AA
NOMESCO Finland
Liquor cerebri shunt X-ray examinatin without contrast
+∞
11.5
11
*
S34.0
ICD-10 Finland
Concussion and oedema of lumbar spinal cord
+∞
11.5
11
*
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.7
11.3
263
1706
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
11.3
270
1769
AEA24
NOMESCO Finland
Removal of spinal stimulation elecrode
35.4
11.3
14
*
AEA00
NOMESCO Finland
Replacement of impulse generator of stimulation device in the nervous system
35.4
11.3
14
*
A02BC03
ATC
lansoprazole; oral
1.7
11.2
273
1798
164
Kela drug reimbursment
Fingolimod
20.3
11.1
16
8
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.6
11.1
389
2832
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.7
11.0
291
1960
L99
ICPC
Musculoskeletal disease other
5.2
11.0
33
65
NAJ12
NOMESCO Finland
Posterior reduction of fracture of cervical spine
43.8
10.9
13
*
UJF32
NOMESCO Finland
Coloscopy
1.7
10.9
251
1622
NG4AA
NOMESCO Finland
Lower leg X-ray examination
4.4
10.9
38
88
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.8
10.8
68
251
XA402
NOMESCO Finland
ENMG
4.8
10.8
35
75
WX702
NOMESCO Finland
Supraglottic ventilation device
2.9
10.8
67
245
L04AA27
ATC
fingolimod; oral
28.3
10.7
14
5
L04AX07
ATC
dimethyl fumarate; oral
28.3
10.7
14
5
M01AH01
ATC
celecoxib; oral (coxibs)
1.9
10.7
176
1018
L29
ICPC
Musculoskeletal sympt/complt other
2.6
10.7
78
314
N30.1
ICD-10 Finland
Interstitial cystitis (chronic)
7.7
10.7
24
32
G04BD
ATC
Drugs for urinary frequency and incontinence
60.6
10.6
12
*
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.8
10.6
70
265
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
2.5
10.6
84
354
ZZA00
NOMESCO Finland
Split skin graft
4.1
10.6
40
100
WX002
NOMESCO Finland
Sedation and analgesia
1.8
10.6
188
1117
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.1
10.5
116
575
R50.9
ICD-10 Finland
Fever, unspecified
2.0
10.5
144
779
ZXD35
NOMESCO Finland
Usual procedure
3.5
10.5
48
142
G82
ICD-10 Finland
Paraplegia and tetraplegia
111.1
10.4
11
*
7410D
ICD-9 Finland
Spina bifida, With hydrocephalus[SPINA BIFIDA APERTA CUM HYDROCEPHALO REG LUMBALIS]
111.1
10.4
11
*
QDG10
NOMESCO Finland
Excision and repair of bedsore of lower limb
+∞
10.4
10
*
T09.3
ICD-10 Finland
Injury of spinal cord, level unspecified
+∞
10.4
10
*
3499X
ICD-9 Finland
Other and unspecified disorders of the nervous system, Unspecified disorders of nervous system
+∞
10.4
10
*
AAF20
NOMESCO Finland
Revision of shunt of ventricle of brain
+∞
10.4
10
*
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
3.4
10.4
49
148
R53
ICD-10 Finland
Malaise and fatigue
1.8
10.4
182
1076
B01AB05
ATC
enoxaparin; parenteral
1.7
10.4
284
1925
A29
ICPC
General symptom/complaint other
2.2
10.4
113
557
ABC50
NOMESCO Finland
Decopression of cervical spinal canal and nerve roots
32.9
10.3
13
*
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
5.4
10.3
30
57
A02BC01
ATC
omeprazole; systemic
1.7
10.2
267
1785
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.9
10.2
165
951
R60.0
ICD-10 Finland
Localized oedema
2.2
10.1
108
525
SPAT1149
SPAT
Suture or treatment of traumatic wound
2.0
10.1
131
692
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
2.8
10.1
64
238
ZXE30
NOMESCO Finland
More than five and less than seven hours
2.8
10.1
66
248
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.6
10.0
389
2884
ABC63
NOMESCO Finland
Decompression of thoracic spinal cord
40.5
10.0
12
*
N06BA07
ATC
modafinil; oral
16.9
9.9
15
9
G04CA01
ATC
alfuzosin; oral
2.1
9.9
118
606
M41.9
ICD-10 Finland
Scoliosis, unspecified
8.2
9.9
21
26
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
4.3
9.8
35
83
D17
ICPC
Incontinence of bowel
8.8
9.8
20
23
G55.2*M47.9
ICD-10 Finland
Nerve root and plexus compressions in spondylosis
6.2
9.7
25
41
U70
ICPC
Pyelonephritis/pyelitis
6.2
9.7
25
41
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
3.7
9.7
41
114
L02
ICPC
Back symptom/complaint
2.3
9.7
91
417
N07XX09
ATC
[U] dimethyl fumarate; oral
55.5
9.7
11
*
D12
ICPC
Constipation
3.5
9.6
43
125
S72.4
ICD-10 Finland
Fracture of lower end of femur
7.9
9.6
21
27
G47.3
ICD-10 Finland
Sleep apnoea
1.7
9.6
208
1316
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
4.7
9.6
31
67
GBB00
NOMESCO Finland
Tracheostomy
7.2
9.5
22
31
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.9
9.5
158
917
ZXE40
NOMESCO Finland
More than seven and less than nine hours
4.4
9.5
33
77
U28
ICPC
Limited function/disability (U)
7.6
9.4
21
28
AEA30
NOMESCO Finland
Replacement of implanted pump of injection device in the nervous system
100.9
9.4
10
*
SPAT1254
SPAT
Administration of medicine
1.9
9.4
139
771
KH1AT
NOMESCO Finland
Urinary tract cathetrisation with ultrasound guidance
30.3
9.4
12
*
QXB99
NOMESCO Finland
Other procedure to treat skin wound, unspecified location
5.4
9.4
27
51
G91.1
ICD-10 Finland
Obstructive hydrocephalus
+∞
9.4
9
*
V89
ICD-10 Finland
Motor- or nonmotor-vehicle accident, type of vehicle unspecified
21.9
9.4
13
6
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.4
9.3
78
338
Y96.9
ICD-10 Finland
Unspecified type of accident
5.3
9.3
27
52
M79.6
ICD-10 Finland
Pain in limb
1.6
9.2
315
2253
XJH00
NOMESCO Finland
Transanal ultrasonography
2.5
9.1
72
305
SPAT1255
SPAT
Intravenous administration of medicine
2.4
9.0
74
318
JN3AD
NOMESCO Finland
Abdominal CT examination
2.4
9.0
79
350
34099
ICD-8 Finland
Multiple sclerosis
37.0
9.0
11
*
G83.1
ICD-10 Finland
Monoplegia of lower limb
37.0
9.0
11
*
N39.9
ICD-10 Finland
Disorder of urinary system, unspecified
5.1
9.0
27
54
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
2.7
9.0
61
237
SPAT1249
SPAT
Treatment-related counselling outside office
1.5
9.0
372
2779
N07BC02
ATC
methadone; systemic
18.8
8.9
13
7
XX1ZW
NOMESCO Finland
Very extensive written report from radiologist
18.8
8.9
13
7
Y86
ICD-10 Finland
Sequelae of other accidents
12.7
8.9
15
12
A02BA02
ATC
ranitidine; systemic
1.7
8.9
182
1131
WX720
NOMESCO Finland
Own respiration
3.1
8.8
46
151
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
8.8
422
3251
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.4
8.8
72
308
N30
ICD-10 Finland
Cystitis
2.3
8.8
78
350
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
6.0
8.8
23
39
R35
ICD-10 Finland
Polyuria
2.4
8.8
70
298
S13.1
ICD-10 Finland
Dislocation of cervical vertebra
50.4
8.7
10
*
R51
NOMESCO Finland
Aids services
50.4
8.7
10
*
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
3.3
8.7
42
131
R11
ICD-10 Finland
Nausea and vomiting
2.3
8.7
80
366
N05BA04
ATC
oxazepam; oral
1.7
8.7
217
1426
Z73.6
ICD-10 Finland
Limitation of activities due to disability
8.3
8.6
18
22
XX6XT
NOMESCO Finland
Other intravascular therapy with radiological guidance
11.7
8.6
15
13
S29
ICPC
Skin symptom/complaint other
1.8
8.5
155
926
L03
ICPC
Low back symptom/complaint
1.7
8.5
213
1398
TAW99
NOMESCO Finland
Other minor neurosurgical procedure
12.9
8.4
14
11
M53.1
ICD-10 Finland
Cervicobrachial syndrome
2.1
8.4
100
511
G95
ICD-10 Finland
Other diseases of spinal cord
+∞
8.3
8
*
34900
ICD-8 Finland
Other diseases of spinal cord, Syringomyelia
+∞
8.3
8
*
Q05.9
ICD-10 Finland
Spina bifida, unspecified
+∞
8.3
8
*
ABC33
NOMESCO Finland
Decompression of thoracic nerve roots
+∞
8.3
8
*
3361A
ICD-9 Finland
Other diseases of spinal cord, Vascular myelopathies
+∞
8.3
8
*
3368X
ICD-9 Finland
Other diseases of spinal cord, Other myelopathy
+∞
8.3
8
*
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
4.7
8.3
27
59
WX882
NOMESCO Finland
High dependency care
3.4
8.3
39
119
SPAT1285
SPAT
Provision of consultation response
2.6
8.3
60
242
N30.2
ICD-10 Finland
Other chronic cystitis
7.1
8.3
19
27
G54.0
ICD-10 Finland
Brachial plexus disorders
4.3
8.2
29
69
ZXE00
NOMESCO Finland
One hour or less
1.5
8.2
364
2748
A41.8
ICD-10 Finland
Other specified sepsis
5.4
8.2
23
43
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.7
8.1
55
212
SPAT1293
SPAT
Other function in accordance with rehabilitation guidance nomenclature
8.2
8.1
17
21
SPAT1125
SPAT
Stoma care and guidance
4.9
8.1
25
52
R32
ICD-10 Finland
Unspecified urinary incontinence
4.0
8.1
31
80
KDV20
NOMESCO Finland
Submucous urethral injection
33.6
8.1
10
*
TAB22
NOMESCO Finland
Stoppin epidural fluid escape with coagulated blood
11.8
8.1
14
12
S12.0
ICD-10 Finland
Fracture of first cervical vertebra
17.3
8.1
12
7
A04
ICPC
Weakness/tiredness general
1.9
8.1
114
623
M41.5
ICD-10 Finland
Other secondary scoliosis
22.2
8.0
11
5
A03FA02
ATC
cisapride; oral, rectal
2.2
8.0
76
354
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.2
8.0
82
392
SAA01
NOMESCO Finland
Simple examination of mouth
1.5
8.0
639
5445
C08CA05
ATC
nifedipine; systemic
2.4
8.0
65
281
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.5
7.9
61
254
R13
ICD-10 Finland
Dysphagia
2.3
7.9
69
306
359
Kela drug reimbursment
Mirabegroni
13.1
7.9
13
10
K07
ICPC
Swollen ankles/oedema
2.8
7.9
47
170
J01MA01
ATC
ofloxacin; systemic
2.1
7.8
88
439
R1410
NOMESCO Finland
Drawing up a rehabilitation plan
8.5
7.8
16
19
S01
ICPC
Pain/tenderness of skin
2.9
7.8
45
158
N03AF01
ATC
carbamazepine; oral, rectal
2.5
7.8
58
239
NAG63
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, more than 3 vertebraea
9.5
7.8
15
16
SPAT1234
SPAT
Support of social functional capacity
2.8
7.8
49
181
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
3.4
7.8
35
104
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.2
7.8
76
357
N02AC04
ATC
dextropropoxyphene; oral
3.0
7.7
44
152
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.8
7.7
49
183
K90
ICPC
Stroke/cerebrovascular accident
4.0
7.7
29
74
H04.10
ICD-10 Finland
Dry eye syndrome
2.1
7.7
89
451
E0000UV
ATC
NA
1.5
7.6
345
2605
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
2.9
7.6
45
162
G99.2*M51.0
ICD-10 Finland
Lumbar and other intervertebral disc disorders with myelopathy
25.2
7.6
10
*
Y88.3
ICD-10 Finland
Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.4
7.6
34
101
M96.1
ICD-10 Finland
Postlaminectomy syndrome, not elsewhere classified
10.1
7.5
14
14
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.5
7.5
301
2216
JHB30
NOMESCO Finland
Rubber band ligature of haemorrhoids or prolapse of mucosa
2.5
7.5
58
243
UJH02
NOMESCO Finland
Anoscopy
2.9
7.5
44
158
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
3.3
7.5
36
113
S82.3
ICD-10 Finland
Fracture of lower end of tibia
4.3
7.4
26
62
R42
ICD-10 Finland
Dizziness and giddiness
1.7
7.4
176
1135
G37.3
ICD-10 Finland
Acute transverse myelitis in demyelinating disease of central nervous system
80.6
7.4
8
*
NA7DM
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with 3 Tesla magnet
80.6
7.4
8
*
G06.1
ICD-10 Finland
Intraspinal abscess and granuloma
80.6
7.4
8
*
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
3.4
7.4
34
103
N06AX11
ATC
mirtazapine; oral
1.5
7.4
277
2007
M01AE03
ATC
ketoprofen; systemic, rectal
1.5
7.4
336
2542
H53.2
ICD-10 Finland
Diplopia
3.5
7.3
32
93
NH1BA
NOMESCO Finland
Ankle extensive X-ray examination
3.6
7.3
31
88
M05BA04
ATC
alendronic acid; oral
2.2
7.3
71
334
80691
ICD-8 Finland
Fracture and fracture dislocation of vertebral column with spinal cord lesion, Thoracica, Sequelae
+∞
7.3
7
*
G91.0
ICD-10 Finland
Communicating hydrocephalus
+∞
7.3
7
*
C72.09
ICD-10 Finland
Malignant tumor of the spinal cord other histology
+∞
7.3
7
*
AAF99
NOMESCO Finland
Other shunt operation on ventricle of brain or intracerebral cyst
+∞
7.3
7
*
G99.2*M47.0
ICD-10 Finland
Anterior spinal and vertebral artery compression syndromes
+∞
7.3
7
*
G96.0
ICD-10 Finland
Cerebrospinal fluid leak
+∞
7.3
7
*
C72.1
ICD-10 Finland
Malignant neoplasm: Cauda equina
+∞
7.3
7
*
M41.4
ICD-10 Finland
Neuromuscular scoliosis
+∞
7.3
7
*
T85.7
ICD-10 Finland
Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
+∞
7.3
7
*
G93.1
ICD-10 Finland
Anoxic brain damage, not elsewhere classified
+∞
7.3
7
*
Y85.0
ICD-10 Finland
Sequelae of motor-vehicle accident
+∞
7.3
7
*
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.3
7.3
63
280
A08
ICPC
Swelling
2.8
7.3
44
161
SAA03
NOMESCO Finland
Extended examination of mouth
1.5
7.3
341
2587
M54.6
ICD-10 Finland
Pain in thoracic spine
2.3
7.3
63
281
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
2.2
7.2
70
327
Z93.5
ICD-10 Finland
Cystostomy status
15.9
7.2
11
7
F43.1
ICD-10 Finland
Post-traumatic stress disorder
4.1
7.2
26
64
H53.1
ICD-10 Finland
Subjective visual disturbances
2.4
7.2
57
243
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.1
7.2
81
405
G81.1
ICD-10 Finland
Spastic hemiplegia
30.2
7.2
9
*
SPAT1153
SPAT
Removal of sutures
1.5
7.1
283
2074
N03AX11
ATC
topiramate; oral
3.6
7.1
30
85
N06AB04
ATC
citalopram; systemic
1.6
7.1
189
1256
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
2.4
7.1
56
238
L03.0
ICD-10 Finland
Cellulitis of finger and toe
2.2
7.1
72
346
N04BC05
ATC
pramipexole; oral
2.2
7.1
70
333
G04.9
ICD-10 Finland
Encephalitis, myelitis and encephalomyelitis, unspecified
12.1
7.1
12
10
PA7BD
NOMESCO Finland
CT angiography of neck and brain
5.7
7.1
19
34
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
3.1
7.1
36
118
S06.0
ICD-10 Finland
Concussion
2.0
7.0
93
499
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
2.3
7.0
59
260
F43.29
ICD-10 Finland
Adaptation disorder UNS
4.0
7.0
26
66
SPAT1211
SPAT
Application of soft bandage
2.0
7.0
86
445
R60.9
ICD-10 Finland
Oedema, unspecified
2.5
7.0
50
203
N06AB10
ATC
escitalopram; oral
1.6
7.0
170
1104
QDG20
NOMESCO Finland
Operation for chronic ulcer or fistula of skin of lower limb
6.4
7.0
17
27
V29.9
ICD-10 Finland
Motorcycle rider [any] injured in unspecified traffic accident
6.4
7.0
17
27
XF400
NOMESCO Finland
ECG with 12 standard connections
1.7
6.9
141
872
XX3DW
NOMESCO Finland
Time consuming IT work
1.9
6.9
94
509
ZXM20
NOMESCO Finland
Intraoperative use of computerised tomography
7.6
6.9
15
20
353
Kela drug reimbursment
Cladribine and fingolimod
13.9
6.9
11
8
F43.20
ICD-10 Finland
Adaptation disorder with short-term depression
4.9
6.9
21
44
XG466
NOMESCO Finland
Sleep oxymetry
3.0
6.8
36
121
M79.0
ICD-10 Finland
Rheumatism, unspecified
3.0
6.8
36
121
Z71.8
ICD-10 Finland
Other specified counselling
1.6
6.8
206
1413
N30.8
ICD-10 Finland
Other cystitis
6.8
6.8
16
24
NFQ20
NOMESCO Finland
Amputation of femur
6.8
6.8
16
24
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
4.0
6.8
25
63
G04BE01
ATC
alprostadil; parenteral, urethral
3.9
6.8
26
68
S14
ICPC
Burn/scald
2.9
6.8
39
137
NAG41
NOMESCO Finland
Anterior fusion of cervical spine with fixation
9.4
6.8
13
14
R06.0
ICD-10 Finland
Dyspnoea
1.6
6.8
215
1492
K02.1
ICD-10 Finland
Caries of dentine
1.4
6.8
503
4161
D33.40
ICD-10 Finland
Benign glioma of the spinal cord (grade I)
40.3
6.8
8
*
L16
ICPC
Ankle symptom/complaint
2.0
6.8
87
462
N32.9
ICD-10 Finland
Bladder disorder, unspecified
16.8
6.7
10
6
U72
ICPC
Urethritis
3.6
6.7
28
79
SPAT1221
SPAT
Guidance concerning rehabilitation services and livelihood
3.6
6.7
28
79
NA1BA
NOMESCO Finland
Cervical spine extensive X-ray examination without contrast
7.2
6.7
15
21
M79.2
ICD-10 Finland
Neuralgia and neuritis, unspecified
4.0
6.7
25
64
N17
ICPC
Vertigo/dizziness
1.9
6.7
92
499
J01CF05
ATC
flucloxacillin; systemic
2.8
6.7
40
146
NAG42
NOMESCO Finland
Posterior fusion of cervical spine with or without fixation
22.7
6.7
9
*
ABW99
NOMESCO Finland
Other operation on spinal cord or nerve root
22.7
6.7
9
*
TAA40
NOMESCO Finland
Cathetrisation of cerebrospinal fluid through skin
22.7
6.7
9
*
AEA20
NOMESCO Finland
Removal of impulse generator of stimulation device in the nervous system
22.7
6.7
9
*
R2120
NOMESCO Finland
Counselling and guidance concerning rehabilitation services and social security
5.9
6.6
17
29
M54.3
ICD-10 Finland
Sciatica
2.3
6.6
58
261
NA2AD
NOMESCO Finland
Thoracic spine CT examination
8.8
6.6
13
15
J01CA04
ATC
amoxicillin; systemic
1.5
6.5
747
6676
WX892
NOMESCO Finland
Monitored bed care
2.1
6.5
70
344
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
3.1
6.5
34
114
NAG62
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, 2-3 vertebraea
3.6
6.5
27
76
B01AA03
ATC
warfarin; systemic
1.6
6.5
160
1043
R1210
NOMESCO Finland
Medical assessment of need and possibilities to rehabilitation
5.1
6.5
19
38
JC2KB
NOMESCO Finland
Functional X-ray examination of swallowing
5.1
6.5
19
38
Y83.8
ICD-10 Finland
Other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.3
6.5
30
92
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
2.9
6.5
37
129
SPAT1296
SPAT
Other function in accordance with occupational therapy nomenclature
6.2
6.5
16
26
M81.9
ICD-10 Finland
Osteoporosis, unspecified
2.8
6.5
38
137
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.1
6.5
67
323
S34.1
ICD-10 Finland
Other injury of lumbar spinal cord
70.3
6.4
7
*
NA7CM
NOMESCO Finland
Spine and spinal cord extensive MRI examination with 3 Tesla magnet
70.3
6.4
7
*
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
2.2
6.4
60
278
J96.1
ICD-10 Finland
Chronic respiratory failure
3.6
6.4
27
77
U99
ICPC
Urinary disease other
7.5
6.4
14
19
TAC99
NOMESCO Finland
Other blockade for chronic pain
7.5
6.4
14
19
AB5BT
NOMESCO Finland
Blockage of nerv root with X-ray guidance
7.5
6.4
14
19
ZZH21
NOMESCO Finland
Graft of patients own bone, small pieces
3.7
6.4
26
72
B01AC07
ATC
dipyridamole; systemic
2.9
6.4
37
132
N04BD01
ATC
selegiline; oral
4.4
6.4
21
48
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.5
6.4
246
1785
G55.1*M51.1
ICD-10 Finland
Compression of nerve roots and nerve plexus in disc diseases in the lumbar region and other regions
3.4
6.4
28
83
M86.9
ICD-10 Finland
Osteomyelitis, unspecified
6.6
6.3
15
23
R90.8
ICD-10 Finland
Other abnormal findings on diagnostic imaging of central nervous system
6.6
6.3
15
23
PA7CD
NOMESCO Finland
CT angiography of neck and brain, extensive
8.2
6.3
13
16
7819X
ICD-9 Finland
Symptoms involving nervous and musculoskeletal systems, Other symptoms involving nervous and musculoskeletal systems[SYMPTOMATA ALIA SYSTEMATIS NERVORUM ET MUSCULOSCEL]
5.2
6.3
18
35
WX199
NOMESCO Finland
Other local analgesia
3.5
6.3
27
78
NE1AD
NOMESCO Finland
Pelvis and hip bones CT examination
4.2
6.3
22
53
M05BX04
ATC
denosumab; parenteral
2.5
6.3
46
189
NF3AA
NOMESCO Finland
Femur X-ray examination
4.0
6.3
23
58
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
3.2
6.3
31
100
J01XX08
ATC
linezolid; systemic
9.3
6.3
12
13
S28
ICPC
Limited function/disability (S)
9.3
6.3
12
13
KH1EE
NOMESCO Finland
Urologic ultrasound examination
9.3
6.3
12
13
G36.9
ICD-10 Finland
Acute disseminated demyelination, unspecified
18.1
6.3
9
5
L14
ICPC
Leg/thigh symptom/complaint
2.1
6.3
66
323
80690
ICD-8 Finland
Fracture and fracture dislocation of vertebral column with spinal cord lesion, Cervicalis, Sequelae
+∞
6.3
6
*
5965X
ICD-9 Finland
Other disorders of bladder, Other functional disorders of bladder[ALIA FUNCTIO LAESA VESICAE URINARIAE]
+∞
6.3
6
*
AAF25
NOMESCO Finland
Removal of shunt of ventricle of brain
+∞
6.3
6
*
A123_
NOMESCO Finland
NA
+∞
6.3
6
*
1601
FHL
Cystometry
+∞
6.3
6
*
2133
FHL
Suntin revisio
+∞
6.3
6
*
M49.4
ICD-10 Finland
Neuropathic spondylopathy
+∞
6.3
6
*
T85.0
ICD-10 Finland
Mechanical complication of ventricular intracranial (communicating) shunt
+∞
6.3
6
*
G992, M480
ICD-10 Finland
NA
+∞
6.3
6
*
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.6
6.2
173
1163
SAA04
NOMESCO Finland
Special inverstigation of mouth
2.3
6.2
53
235
XF600
NOMESCO Finland
Bloodpressure measurement
2.3
6.2
56
256
WZA90
NOMESCO Finland
Other doctors statement
1.6
6.2
195
1349
R30.0
ICD-10 Finland
Dysuria
2.9
6.2
36
129
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.7
6.2
116
698
WX872
NOMESCO Finland
Intensive care
2.3
6.2
51
224
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
2.2
6.2
56
257
ZXE17
NOMESCO Finland
Procedure duration 150 to 179 minutes
5.8
6.2
16
28
KF8AE
NOMESCO Finland
Ultrasound examination of scrotum
3.3
6.1
29
91
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
4.3
6.1
21
50
G44.2
ICD-10 Finland
Tension-type headache
1.8
6.1
109
646
R52.1
ICD-10 Finland
Chronic intractable pain
7.7
6.1
13
17
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
4.1
6.1
22
55
1530
FHL
Urethrocystoscopy
3.8
6.1
24
65
A02BC05
ATC
esomeprazole; systemic
1.4
6.1
351
2754
V28.2
ICD-10 Finland
Motorcycle rider injured in noncollision transport accident, unspecified motorcycle rider injured in nontraffic accident
12.6
6.1
10
8
NA3CM
NOMESCO Finland
Lumbar spine extensive MRI examination with 3 Tesla magnet
12.6
6.1
10
8
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.0
6.0
75
392
A02BA04
ATC
nizatidine; systemic
2.0
6.0
71
365
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
2.7
6.0
39
149
SAA02
NOMESCO Finland
Basic examination of mouth
1.4
6.0
572
4899

Mortality – FinRegistry

Association

Association between endpoint G6_SPINOTH and mortality.

Females

Parameter HR [95% CI] p-value
G6_SPINOTH 2.357 [2.03, 2.73] < 0.001
Birth year 0.994 [0.99, 1.0] 0.146

During the follow-up period (1.1.1998 — 31.12.2019), 600 out of 2883 females with G6_SPINOTH died.

Males

Parameter HR [95% CI] p-value
G6_SPINOTH 2.303 [2.02, 2.62] < 0.001
Birth year 0.988 [0.98, 1.0] 0.014

During the follow-up period (1.1.1998 — 31.12.2019), 902 out of 3328 males with G6_SPINOTH died.

Mortality risk

Mortality risk for people of age

years, who have G6_SPINOTH.

N-year risk Females Males
1 0.185% 0.515%
5 1.342% 2.816%
10 3.579% 7.176%
15 6.771% 13.09%
20 11.097% 21.615%

Relationships between endpoints

Index endpoint: G6_SPINOTH – Other diseases of spinal cord

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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