Polyarteritis Nodosa: ['A necrotizing vasculitis that affects medium-sized arteries, it is usually idiopathic, and may be triggered by viral infections (Hepatitis B, also others). A multisystem disease, it most commonly affects skin (nodules, livedo reticularis) and peripheral nerves; higher morbidity is associated with gastrointestinal, central nervous system, cardiac, and/or other organ involvement. Anti-neutrophil cytoplasmic antibodies (ANCA) are typically negative. [ NCI ]']
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
418 |
4. Check minimum number of eventsNone |
418 |
5. Include endpoints |
456 |
6. Filter based on genotype QC (FinnGen only) |
439 |
Control definitions (FinnGen only)
- Control exclude
- M13_SYSTCONNECT
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- M30-M36
- Name in latin
- Polyarteritis nodosa et condiciones cognatae
Similar endpoints
↥List of similar endpoints to
Polyarteritis nodosa and related conditions
based on the number of shared cases.
Similar with more cases:
- Systemic connective tissue disorders
- Autoimmune diseases related-to ILD
- Diseases of the musculoskeletal system and connective tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 5194 | 2773 | 2381 |
| Only index persons | 3827 | 2036 | 1791 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.07 | 0.08 | 0.07 |
| Only index persons | 0.07 | 0.07 | 0.07 |
| Median age at first event (years) | |||
| Whole population | 43.91 | 57.85 | 27.24 |
| Only index persons | 38.04 | 54.00 | 19.89 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 439 | 257 | 182 |
| Unadjusted period prevalence (%) | 0.10 | 0.10 | 0.09 |
| Median age at first event (years) | 53.52 | 52.24 | 55.33 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 456
- Matched controls
- 4561
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M30.0
ICD-10 Finland
Polyarteritis nodosa
+∞
194.0
172
*
M30.1
ICD-10 Finland
Polyarteritis with lung involvement [Churg-Strauss]
+∞
135.3
123
*
M30.8
ICD-10 Finland
Other conditions related to polyarteritis nodosa
+∞
86.2
80
*
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
10.8
72.8
154
205
H02AB06
ATC
prednisolone; systemic
5.8
65.8
329
1401
L04AX01
ATC
azathioprine; systemic
16.5
63.6
106
82
M30.3
ICD-10 Finland
Mucocutaneous lymph node syndrome [Kawasaki]
+∞
53.2
50
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
4.3
45.2
238
922
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
8.9
38.6
87
118
N08.5*M30.0
ICD-10 Finland
Glomerular disorders in polyarteritis nodosa
+∞
35.9
34
*
M31.3
ICD-10 Finland
Wegener granulomatosis
+∞
35.9
34
*
D72.1
ICD-10 Finland
Eosinophilia
68.9
33.6
38
6
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
6.4
32.7
92
172
L04AA06
ATC
mycophenolic acid; systemic
22.1
31.6
46
23
4461A
ICD-9 Finland
Polyarteritis nodosa and allied conditions, Acute febrile mucocutaneous lymph node syndrome [MCLS]
+∞
29.5
28
*
M05BA04
ATC
alendronic acid; oral
5.8
29.1
88
179
J45.9
ICD-10 Finland
Asthma, unspecified
3.9
28.8
138
452
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
3.8
28.8
148
514
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.0
27.7
246
1270
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
7.5
25.8
63
95
M31.9
ICD-10 Finland
Necrotizing vasculopathy, unspecified
+∞
25.2
24
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
4.7
24.9
93
237
R50.9
ICD-10 Finland
Fever, unspecified
3.9
24.3
114
360
L01AA01
ATC
cyclophosphamide; systemic
59.5
24.3
28
5
N08.5
ICD-10 Finland
Glomerular disorders in systemic connective tissue disorders
+∞
24.2
23
*
M31.8
ICD-10 Finland
Other specified necrotizing vasculopathies
+∞
24.2
23
*
H02AB07
ATC
prednisone; oral
4.1
24.0
106
317
J45.1
ICD-10 Finland
Nonallergic asthma
5.6
23.6
73
151
L95.9
ICD-10 Finland
Vasculitis limited to skin, unspecified
38.6
23.3
29
8
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
10.0
23.2
47
52
J18.9
ICD-10 Finland
Pneumonia, unspecified
3.0
22.4
160
690
M31.7
ICD-10 Finland
Microscopic polyangiitis
+∞
22.1
21
*
J01MA12
ATC
levofloxacin; systemic
3.5
22.0
121
430
N08.5*M31.3
ICD-10 Finland
Glomerular disorders in Wegener's granulomatosis
+∞
21.0
20
*
TGC00
NOMESCO Finland
Bronchial lavation
12.5
20.6
37
32
UDH02
NOMESCO Finland
Rhinopharyngoscopy
5.5
20.3
63
130
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
7.0
19.8
50
79
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
5.5
19.8
61
125
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
7.1
19.3
48
74
C03CA01
ATC
furosemide; systemic
2.7
19.3
169
813
ZX120
NOMESCO Finland
Intravenous
4.2
19.2
79
219
P01BA02
ATC
hydroxychloroquine; oral
5.2
19.0
61
131
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
4.2
18.8
77
212
H02AB04
ATC
methylprednisolone; systemic
3.4
18.0
98
342
J32.4
ICD-10 Finland
Chronic pansinusitis
15.6
17.4
28
19
A02BC02
ATC
pantoprazole; systemic
2.4
17.3
305
2086
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
+∞
16.8
16
*
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
5.4
16.7
51
103
I77.6
ICD-10 Finland
Arteritis, unspecified
+∞
15.7
15
*
M31.5
ICD-10 Finland
Giant cell arteritis with polymyalgia rheumatica
88.2
15.7
17
*
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
88.2
15.7
17
*
R03DC03
ATC
montelukast; oral
3.0
15.6
100
389
R03AC12
ATC
salmeterol; inhalant
6.2
15.5
42
73
J01FF01
ATC
clindamycin; systemic
2.5
15.3
151
759
J45.0
ICD-10 Finland
Predominantly allergic asthma
3.8
14.9
67
199
UGC12
NOMESCO Finland
Flexible bronchoscopy
4.1
14.9
60
162
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
7.7
14.8
34
47
N02AX02
ATC
tramadol; systemic, rectal
2.3
14.7
205
1213
N08.5*M31.7
ICD-10 Finland
Glomerular disease states in microscopic polyangiitis
+∞
14.7
14
*
4460A
ICD-9 Finland
Polyarteritis nodosa and allied conditions, Polyarteritis nodosa[POLYARTERITIS NODOSA (CLASSICA)]
+∞
14.7
14
*
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
154.8
14.5
15
*
R03AK06
ATC
salmeterol and fluticasone; inhalant
3.1
14.5
88
326
N03AX16
ATC
pregabalin; oral
2.6
14.4
127
596
D69.0
ICD-10 Finland
Allergic purpura
19.9
14.4
21
11
TDM10
NOMESCO Finland
Puncture of maxillary antrum
6.2
14.1
38
66
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
9.8
13.7
27
29
M31.1
ICD-10 Finland
Thrombotic microangiopathy
+∞
13.6
13
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.8
13.6
95
389
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
4.0
13.4
55
151
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.4
13.4
142
732
R01AD08
ATC
fluticasone; nasal
2.3
13.4
147
769
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
3.6
13.3
63
196
PAW37
NOMESCO Finland
Biopsy of temporal artery
41.4
13.2
16
*
TPH04
NOMESCO Finland
Cathetrisation of vein
2.5
13.2
116
540
Z01.8
ICD-10 Finland
Other specified special examinations
2.6
13.2
113
518
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
8.5
13.0
28
35
R03AK08
ATC
formoterol and beclometasone; inhalant
6.6
13.0
33
53
R03AC02
ATC
salbutamol; inhalant
2.1
12.9
253
1707
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.6
12.7
103
457
N085, M318
ICD-10 Finland
NA
+∞
12.6
12
*
M35.3
ICD-10 Finland
Polymyalgia rheumatica
13.7
12.5
21
16
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
6.3
12.5
33
56
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.7
12.5
92
387
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
4.1
12.4
49
130
J01MA14
ATC
moxifloxacin; systemic
3.5
12.1
59
187
J82
ICD-10 Finland
Pulmonary eosinophilia, not elsewhere classified
27.5
12.1
16
6
J45.8
ICD-10 Finland
Mixed asthma
6.4
12.0
31
51
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
4.9
12.0
39
85
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
3.6
11.9
54
162
A02BC01
ATC
omeprazole; systemic
2.2
11.9
143
773
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.4
11.9
115
562
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
3.4
11.8
59
191
R03BB04
ATC
tiotropium bromide; inhalant
3.3
11.6
60
200
F02.89*M30.0
ICD-10 Finland
Dementia in polyarteritis nodosa
+∞
11.5
11
*
M31.0
ICD-10 Finland
Hypersensitivity angiitis
+∞
11.5
11
*
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
10.9
11.4
21
20
XG474
NOMESCO Finland
Exhalation nntrogen oxide
6.4
11.2
29
48
XG410
NOMESCO Finland
Flow-volume spirometry
4.7
11.2
38
87
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
4.1
11.1
44
117
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.3
11.1
56
183
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
7.2
11.0
26
38
J01MA02
ATC
ciprofloxacin; systemic
2.0
11.0
184
1140
N30.1
ICD-10 Finland
Interstitial cystitis (chronic)
12.3
10.9
19
16
DHA10
NOMESCO Finland
Biopsy of cavity of nose
16.0
10.9
17
11
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
7.3
10.7
25
36
DPA30
NOMESCO Finland
Sphenotomy
61.5
10.7
12
*
L04AA01
ATC
[U] ciclosporin; systemic
10.4
10.6
20
20
M32.1
ICD-10 Finland
Systemic lupus erythematosus with organ or system involvement
+∞
10.5
10
*
N08.5*M32.1
ICD-10 Finland
Glomerular disorders in systemic lupus erythematosus
+∞
10.5
10
*
J47
ICD-10 Finland
Bronchiectasis
11.7
10.1
18
16
R03BA05
ATC
fluticasone; inhalant
2.3
10.1
100
489
J33.0
ICD-10 Finland
Polyp of nasal cavity
6.0
10.1
27
47
H26.3
ICD-10 Finland
Drug-induced cataract
41.0
10.0
12
*
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
3.3
9.9
50
163
Z49.1
ICD-10 Finland
Extracorporeal dialysis
9.0
9.9
20
23
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.8
9.9
67
265
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
26.7
9.9
13
5
A12AA04
ATC
calcium carbonate; oral
9.9
9.9
19
20
A11CC03
ATC
alfacalcidol; systemic
5.8
9.8
27
49
R03BA02
ATC
budesonide; inhalant
2.3
9.7
97
475
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
3.6
9.7
43
127
R03DA04
ATC
theophylline; systemic, rectal
4.0
9.7
38
101
N02AA05
ATC
oxycodone; systemic
2.6
9.6
75
324
R03AC13
ATC
formoterol; inhalant
4.3
9.5
34
83
G58.7
ICD-10 Finland
Mononeuritis multiplex
102.1
9.4
10
*
44600
ICD-8 Finland
Polyarteritis nodosa and allied conditions, Polyarteritis nodosa
+∞
9.4
9
*
H02AB09
ATC
hydrocortisone; systemic
5.3
9.2
27
53
A12BA01
ATC
potassium chloride; oral
4.2
9.2
34
86
M05BA01
ATC
etidronic acid; systemic
37.5
9.1
11
*
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
3.3
9.0
45
147
A46
ICD-10 Finland
Erysipelas
2.5
8.9
72
317
XW000
NOMESCO Finland
Bone marrow biopsy
4.6
8.9
30
69
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.3
8.9
45
148
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.3
8.9
92
459
C08CA01
ATC
amlodipine; oral
1.9
8.7
152
937
L95.8
ICD-10 Finland
Other vasculitis limited to skin
16.7
8.6
13
8
D64.9
ICD-10 Finland
Anaemia, unspecified
2.8
8.6
57
224
J33.8
ICD-10 Finland
Other polyp of sinus
6.2
8.6
22
37
JN6DR
NOMESCO Finland
PET-CT of whole body metabolism
20.5
8.5
12
6
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
6.9
8.5
20
30
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.3
8.4
85
418
J01DB01
ATC
cefalexin; oral
2.0
8.4
361
3010
Z94.0
ICD-10 Finland
Kidney transplant status
8.8
8.4
17
20
N08.5*M31.0
ICD-10 Finland
Glomerular disorders in Goodpasture's syndrome
+∞
8.4
8
*
297
Kela drug reimbursment
NA
+∞
8.4
8
*
3028
Kela drug reimbursment
Mepolizumab
+∞
8.4
8
*
R03DX09
ATC
mepolizumab; parenteral
+∞
8.4
8
*
L95.0
ICD-10 Finland
Livedoid vasculitis
+∞
8.4
8
*
R03AK07
ATC
formoterol and budesonide; inhalant
2.2
8.3
90
457
R01AD01
ATC
beclometasone; nasal
2.3
8.2
77
365
R07.4
ICD-10 Finland
Chest pain, unspecified
2.0
8.2
127
749
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.5
8.2
37
112
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
4.5
8.2
28
66
WX408
NOMESCO Finland
General anesthesy, balanced
2.0
8.2
128
755
S97
ICPC
Chronic ulcer skin
3.8
8.1
33
91
DHB20
NOMESCO Finland
Polypectomy of internal nose
9.2
8.1
16
18
GX1L5
NOMESCO Finland
Exhaled nitric oxide analysis
22.5
8.0
11
5
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.2
8.0
85
428
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.8
8.0
53
206
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.2
7.9
86
438
R03BA01
ATC
beclometasone; inhalant
2.4
7.9
72
336
M13.9
ICD-10 Finland
Arthritis, unspecified
3.1
7.8
41
139
N06AA09
ATC
amitriptyline; systemic
2.7
7.8
52
204
A12AA12
ATC
[U] calcium acetate anhydrous; systemic
45.8
7.7
9
*
N03AX12
ATC
gabapentin; oral
2.3
7.7
74
357
KCV04
NOMESCO Finland
Distension of bladder with fluid
12.1
7.6
13
11
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
12.1
7.6
13
11
A01AB09
ATC
miconazole; local oral
2.8
7.6
49
190
127
Kela drug reimbursment
Transplant complication
7.3
7.5
17
24
C07AB07
ATC
bisoprolol; oral
1.8
7.5
202
1422
4939X
ICD-9 Finland
Asthma, unspecified[ASTHMA BRONCHIALE NUD]
6.1
7.5
19
32
GD1AD
NOMESCO Finland
Thorax CT examination
4.3
7.4
26
63
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
3.5
7.4
33
99
R03BA08
ATC
ciclesonide; inhalant
2.9
7.3
43
157
M35.1
ICD-10 Finland
Other overlap syndromes
+∞
7.3
7
*
M31.6
ICD-10 Finland
Other giant cell arteritis
+∞
7.3
7
*
4476A
ICD-9 Finland
Other disorders of arteries and arterioles, Arteritis, unspecified
+∞
7.3
7
*
UDM02
NOMESCO Finland
Sinoscopy
6.0
7.3
19
33
TK800
NOMESCO Finland
Hemodialysis
5.2
7.2
21
42
L04AD01
ATC
ciclosporin; systemic
5.8
7.1
19
34
J46
ICD-10 Finland
Status asthmaticus
4.5
7.1
24
56
A02BC05
ATC
esomeprazole; systemic
1.8
7.1
171
1159
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
4.2
7.0
25
62
J01FA06
ATC
roxithromycin; oral
1.7
7.0
179
1237
A07AA02
ATC
nystatin; oral
3.1
7.0
37
127
R03AK04
ATC
salbutamol and sodium cromoglicate; inhalant
14.0
6.9
11
8
N30.0
ICD-10 Finland
Acute cystitis
2.2
6.9
75
380
TQW80
NOMESCO Finland
Local dermatologic skincare
5.2
6.9
20
40
N18.0
ICD-10 Finland
End-stage renal disease
8.5
6.9
14
17
WZC30
NOMESCO Finland
Teaching
2.3
6.9
64
303
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
5.5
6.8
19
36
FJA10
NOMESCO Finland
Transvenous biopsy of right ventricle
40.7
6.8
8
*
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.8
6.8
43
165
B03XA02
ATC
darbepoetin alfa; parenteral
6.6
6.7
16
25
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
2.0
6.7
96
546
TPH07
NOMESCO Finland
Cathetrisation of artery
2.5
6.7
53
232
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.9
6.6
99
572
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.5
6.6
49
206
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.8
6.6
42
161
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
8.9
6.6
13
15
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.1
6.5
73
376
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
3.7
6.5
27
77
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.7
6.5
198
1429
A02BC03
ATC
lansoprazole; oral
1.8
6.5
129
820
Z2446
NOMESCO Finland
Social worker
2.6
6.5
45
182
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
4.5
6.4
21
48
B01AA03
ATC
warfarin; systemic
2.0
6.4
92
519
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
5.0
6.4
19
39
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.7
6.4
224
1679
R06AE07
ATC
cetirizine; oral
1.7
6.4
190
1361
ZX100
NOMESCO Finland
Oral
6.7
6.4
15
23
R03AK11
ATC
formoterol and fluticasone; inhalant
5.7
6.4
17
31
R03DC01
ATC
zafirlukast; oral
6.1
6.4
16
27
J99.1*M31.3
ICD-10 Finland
Respiratory disorders in Wegener's granulomatosis
+∞
6.3
6
*
N08.5*M31.1
ICD-10 Finland
Glomerular disorders in thrombotic thrombocytopenic purpura
+∞
6.3
6
*
M32.8
ICD-10 Finland
Other forms of systemic lupus erythematosus
+∞
6.3
6
*
N085, M319
ICD-10 Finland
NA
+∞
6.3
6
*
M81.4
ICD-10 Finland
Drug-induced osteoporosis
27.1
6.2
8
*
WX892
NOMESCO Finland
Monitored bed care
2.5
6.2
46
193
J01FA10
ATC
azithromycin; systemic
1.6
6.2
249
1933
AA1AD
NOMESCO Finland
CT of head and brain
1.8
6.1
105
636
1XC02
NOMESCO Finland
NA
12.7
6.1
10
8
JN4AD
NOMESCO Finland
Body CT examination
2.7
6.1
39
150
R19.8
ICD-10 Finland
Other specified symptoms and signs involving the digestive system and abdomen
10.2
6.1
11
11
ZXD05
NOMESCO Finland
Urgent procedure
1.7
6.0
142
946
Mortality – FinRegistry
↥Association
Association between endpoint M13_POLYARTERETAL and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_POLYARTERETAL | 2.265 [1.92, 2.68] | < 0.001 |
| Birth year | 0.993 [0.98, 1.0] | 0.11 |
During the follow-up period (1.1.1998 — 31.12.2019), 770 out of 2094 females with M13_POLYARTERETAL died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_POLYARTERETAL | 2.27 [1.8, 2.86] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.006 |
During the follow-up period (1.1.1998 — 31.12.2019), 372 out of 1721 males with M13_POLYARTERETAL died.
Mortality risk
Mortality risk for people of age
years, who have M13_POLYARTERETAL.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.176% | 0.466% |
| 5 | 1.242% | 2.493% |
| 10 | 3.117% | 6.549% |
| 15 | 6.191% | 12.498% |
| 20 | 10.063% | 20.251% |
Relationships between endpoints
↥Index endpoint: M13_POLYARTERETAL – Polyarteritis nodosa and related conditions
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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