Allergic contact dermatitis

L12_ALLERGICCONTACT

allergic contact dermatitis: An inflammatory skin condition caused by an immune response to direct contact between the skin and an allergen. It consists of a delayed type of allergic reaction at the affected site with resulting red, swollen, and blistered skin that may itch or leak.

Suggest a new description

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 L23
  • Hospital discharge: ICD-9 6920B|6921B|6922B|6924B|6924D|6924H|6924L|6925B|6925D|6926B|6926D
  • Cause of death: ICD-10 L23
  • Cause of death: ICD-9 6920B|6921B|6922B|6924B|6924D|6924H|6924L|6925B|6925D|6926B|6926D

2 out of 7 registries used, show all original rules.

6109

4. Check minimum number of events

None

6109

5. Include endpoints

None

6109

6. Filter based on genotype QC (FinnGen only)

6109

Control definitions (FinnGen only)

Control exclude
L12_DERMATITISECZEMA

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
L20-L30
Name in latin
Eczema (allergicum) ex contactu

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 43120 31110 11862
Only index persons 41106 30055 11051
Unadjusted period prevalence (%)
Whole population 0.73 0.89 0.33
Only index persons 0.92 1.10 0.42
Median age at first event (years)
Whole population 44.15 44.70 42.75
Only index persons 44.01 44.48 42.72

-FinnGen-

Key figures

All Female Male
Number of individuals 6109 4783 1326
Unadjusted period prevalence (%) 1.40 1.63 0.58
Median age at first event (years) 47.82 46.67 51.97

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
5511
Matched controls
55109
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L23.9
ICD-10 Finland
Allergic contact dermatitis, unspecified cause
304.9
323.0
979
39
L30.3
ICD-10 Finland
Infective dermatitis
34.0
323.0
544
177
L30.9
ICD-10 Finland
Dermatitis, unspecified
16.0
323.0
2595
2900
E0000UV
ATC
NA
6.1
323.0
3620
13186
317
Kela drug reimbursment
Topical pimecrolimus and tacrolimus
+∞
323.0
325
*
D07AC13
ATC
mometasone; topical
5.7
323.0
2804
8516
XQ800
NOMESCO Finland
Prick test
20.5
323.0
2037
1530
D07AB02
ATC
hydrocortisone butyrate; topical
3.8
323.0
2272
8556
L20.0
ICD-10 Finland
Besnier prurigo
+∞
323.0
1377
*
XQ802
NOMESCO Finland
Epicutan test
257.5
323.0
2742
211
L23.2
ICD-10 Finland
Allergic contact dermatitis due to cosmetics
1185.4
323.0
1348
15
L23.8
ICD-10 Finland
Allergic contact dermatitis due to other agents
749.3
323.0
831
13
D07AD01
ATC
clobetasol; topical
4.9
323.0
1470
3811
L23.5
ICD-10 Finland
Allergic contact dermatitis due to other chemical products
1141.9
323.0
1100
12
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
32.0
323.0
2929
1887
L23.1
ICD-10 Finland
Allergic contact dermatitis due to adhesives
932.4
323.0
509
6
L23.3
ICD-10 Finland
Allergic contact dermatitis due to drugs in contact with skin
521.1
323.0
729
16
D07AB08
ATC
desonide; topical
6.7
323.0
1171
2128
E000001
ATC
NA
5.5
323.0
2087
5508
L20.9
ICD-10 Finland
Atopic dermatitis, unspecified
+∞
323.0
950
*
L23.0
ICD-10 Finland
Allergic contact dermatitis due to metals
5083.8
323.0
1541
*
D07AC01
ATC
betamethasone; topical
5.2
323.0
2958
10089
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
4.9
320.2
1187
2905
E000002
ATC
NA
5.1
319.2
1135
2654
D07BC01
ATC
betamethasone and antiseptics; topical
5.1
312.1
1118
2630
L20
ICD-10 Finland
Atopic dermatitis
+∞
283.8
270
*
R06AE07
ATC
cetirizine; oral
2.6
252.8
3056
17638
D07AA02
ATC
hydrocortisone; topical
4.0
249.8
1150
3396
D07CC01
ATC
betamethasone and antibiotics; topical
4.0
241.8
1128
3360
H02AB06
ATC
prednisolone; systemic
2.6
237.1
2901
16619
D02AE01
ATC
carbamide; topical
5.9
225.4
683
1289
D11AH01
ATC
tacrolimus; topical
1063.0
210.7
205
*
E000006
ATC
NA
5.1
203.3
699
1521
R06AX27
ATC
desloratadine; oral
2.5
189.9
2028
10392
D07BA04
ATC
hydrocortisone and antiseptics; topical
4.0
183.9
812
2257
L24.0
ICD-10 Finland
Irritant contact dermatitis due to detergents
468.0
183.2
182
*
E000003
ATC
NA
6.9
182.8
484
756
L30.8
ICD-10 Finland
Other specified dermatitis
15.1
173.3
296
206
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
4.5
167.2
644
1564
D02AX
ATC
Other emollients and protectives
8.3
166.4
388
499
TQW80
NOMESCO Finland
Local dermatologic skincare
12.9
156.3
286
233
E000007
ATC
NA
5.2
154.4
519
1087
L30.0
ICD-10 Finland
Nummular dermatitis
11.0
152.3
301
288
R06AE09
ATC
levocetirizine; oral
2.8
145.8
1115
4599
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
2.5
142.1
1406
6704
D07XC01
ATC
betamethasone, combinations; topical
3.3
141.1
796
2666
D09AB01
ATC
zinc bandage without supplements; topical
16.3
140.9
233
149
L23
ICD-10 Finland
Allergic contact dermatitis
30.1
133.4
181
62
E000004
ATC
NA
10.0
133.2
277
291
L23.4
ICD-10 Finland
Allergic contact dermatitis due to dyes
430.7
127.4
127
*
L25.9
ICD-10 Finland
Unspecified contact dermatitis, unspecified cause
38.7
123.6
158
42
L20.8
ICD-10 Finland
Other atopic dermatitis
+∞
119.2
114
*
L24.8
ICD-10 Finland
Irritant contact dermatitis due to other agents
402.7
119.1
119
*
R06AX22
ATC
ebastine; oral
2.4
114.8
1214
5895
L30.1
ICD-10 Finland
Dyshidrosis [pompholyx]
92.1
113.5
126
14
WXQ27
NOMESCO Finland
UVB narrow spectrum light therapy
22.3
111.9
165
76
D07AC14
ATC
methylprednisolone aceponate; topical
4.7
111.1
403
908
T78.4
ICD-10 Finland
Allergy, unspecified
4.3
111.0
438
1073
69100
ICD-8 Finland
Infantile eczema and related conditions, Eczema atopicum. Prurigo Besnier. Eczema pruriginosum allergicum
+∞
107.6
103
*
S87
ICPC
Dermatitis/atopic eczema
9.3
106.5
229
255
J30.10
ICD-10 Finland
Allergic rhinitis due to pollen
3.9
103.0
463
1276
C01CA24
ATC
epinephrine; parenteral
3.4
101.7
530
1649
J01DB01
ATC
cefalexin; oral
2.1
100.7
4542
38146
R03AC02
ATC
salbutamol; inhalant
1.8
94.9
2991
21879
L50.3
ICD-10 Finland
Dermatographic urticaria
8.9
94.8
209
243
6918B
ICD-9 Finland
Atopic dermatitis and related conditions, Other atopic dermatitis and related conditions[ECZEMA ATOPICUM]
+∞
91.9
88
*
L23.6
ICD-10 Finland
Allergic contact dermatitis due to food in contact with skin
141.0
91.3
97
7
D11AX14
ATC
[U] tacrolimus; topical
+∞
90.9
87
*
N05BB01
ATC
hydroxyzine; systemic
3.4
89.3
467
1452
L24.9
ICD-10 Finland
Irritant contact dermatitis, unspecified cause
51.9
88.9
107
21
S01GX01
ATC
cromoglicic acid; ophthalmic
2.1
88.8
1291
7122
L23.7
ICD-10 Finland
Allergic contact dermatitis due to plants, except food
292.9
84.9
86
*
R06AX13
ATC
loratadine; oral
2.1
77.3
1011
5294
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.7
76.4
574
2272
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.9
74.1
505
1881
D07CA01
ATC
hydrocortisone and antibiotics; topical
2.3
73.0
798
3846
J01DA01
ATC
[U] cefalexin; systemic
1.7
73.0
3435
27310
D11AH02
ATC
pimecrolimus; topical
+∞
71.0
68
*
J01FF01
ATC
clindamycin; systemic
1.8
70.8
1464
9082
H02AB07
ATC
prednisone; oral
2.2
70.6
798
3903
D05BB02
ATC
acitretin; oral
7.3
68.5
171
242
WIX00
NOMESCO Finland
Allergy cleanup guidance
145.8
68.1
72
5
XQ899
NOMESCO Finland
Other assessment of skin
22.9
68.0
99
44
H02AB04
ATC
methylprednisolone; systemic
2.1
62.7
810
4182
R03DC03
ATC
montelukast; oral
2.0
62.4
953
5266
L27.2
ICD-10 Finland
Dermatitis due to ingested food
113.0
61.9
67
6
L40.0
ICD-10 Finland
Psoriasis vulgaris
3.9
61.2
266
707
D07AB01
ATC
clobetasone; topical
4.2
60.4
241
592
XQ848
NOMESCO Finland
Dermatological photography
5.8
60.0
177
314
J45.9
ICD-10 Finland
Asthma, unspecified
2.0
60.0
926
5131
S88
ICPC
Dermatitis contact/allergic
5.3
55.9
177
342
WXQ12
NOMESCO Finland
Psoralen - Ultraviolet A therapy with local sensitivisation
34.7
55.4
72
21
L21.8
ICD-10 Finland
Other seborrhoeic dermatitis
13.1
54.4
97
75
R03BA05
ATC
fluticasone; inhalant
1.8
53.6
1010
5985
J30.3
ICD-10 Finland
Other allergic rhinitis
3.4
51.0
265
815
SPAT1263
SPAT
Sampling
1.6
50.3
2199
16472
L50.8
ICD-10 Finland
Other urticaria
5.2
50.3
163
324
L29.9
ICD-10 Finland
Pruritus, unspecified
6.3
50.1
138
225
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.8
49.8
950
5637
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
3.3
49.1
266
844
L50.9
ICD-10 Finland
Urticaria, unspecified
3.4
48.5
248
753
L28.0
ICD-10 Finland
Lichen simplex chronicus
26.1
48.1
67
26
L27.0
ICD-10 Finland
Generalized skin eruption due to drugs and medicaments
13.1
47.7
85
66
S29
ICPC
Skin symptom/complaint other
1.9
47.0
818
4695
6924B
ICD-9 Finland
Contact dermatitis and other eczema, Due to other chemical products[DERMATITIS ARTEFACTA E METALLIS ALLERGICA]
+∞
46.9
45
*
L50.0
ICD-10 Finland
Allergic urticaria
3.9
45.3
196
519
D07XB05
ATC
dexamethasone, combinations; topical
4.1
44.9
182
455
R01AD09
ATC
mometasone; nasal
1.5
43.3
2455
19282
A46
ICD-10 Finland
Erysipelas
2.1
43.2
566
2913
WQ007
NOMESCO Finland
NA
80.8
42.9
48
6
J01AA04
ATC
lymecycline; systemic
1.8
42.1
765
4444
D11AX15
ATC
[U] pimecrolimus; topical
+∞
41.7
40
*
N02BE01
ATC
paracetamol; systemic, rectal
1.6
41.5
4483
40306
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
41.2
1292
8810
L28.1
ICD-10 Finland
Prurigo nodularis
60.5
41.2
48
8
J01AA02
ATC
doxycycline; systemic
1.5
40.0
4022
35338
R01AD08
ATC
fluticasone; nasal
1.5
39.6
1541
11064
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.9
39.3
630
3495
A02BC02
ATC
pantoprazole; systemic
1.5
39.3
3167
26511
R06.0
ICD-10 Finland
Dyspnoea
1.6
39.2
1098
7254
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
39.0
1051
6869
D06AX01
ATC
fusidic acid; topical (antibiotics for topical use)
2.0
38.7
520
2698
D07CB01
ATC
triamcinolone and antibiotics; topical
4.3
38.5
149
357
J01AA07
ATC
tetracycline; systemic
1.7
38.5
860
5324
J02AC01
ATC
fluconazole; systemic
1.5
38.4
2351
18591
A92
ICPC
Allergy/allergic reaction NOS
3.4
37.9
191
574
D05AX52
ATC
calcipotriol, combinations; topical
2.6
37.3
282
1111
H10.1
ICD-10 Finland
Acute atopic conjunctivitis
3.7
37.1
169
469
L21.0
ICD-10 Finland
Seborrhoea capitis
9.8
34.9
71
73
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.5
34.6
1408
10151
M25.5
ICD-10 Finland
Pain in joint
1.5
34.6
1456
10577
L98.9
ICD-10 Finland
Disorder of skin and subcutaneous tissue, unspecified
5.4
34.3
106
201
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.8
34.1
617
3560
L40.3
ICD-10 Finland
Pustulosis palmaris et plantaris
5.0
34.0
111
224
D11AH04
ATC
alitretinoin; oral
176.0
33.7
35
*
L71.8
ICD-10 Finland
Other rosacea
4.9
33.7
113
235
XQ801
NOMESCO Finland
Intracutantest
11.1
33.6
64
58
D06BX01
ATC
metronidazole; topical
1.9
33.5
571
3230
Z09.8
ICD-10 Finland
Follow-up examination after other treatment for other conditions
2.7
33.0
233
879
J02AC02
ATC
itraconazole; systemic
1.6
32.6
923
6077
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.4
32.3
1789
13722
J45
ICD-10 Finland
Asthma
1.9
32.1
487
2638
R03BA02
ATC
budesonide; inhalant
1.6
31.9
872
5687
L29.8
ICD-10 Finland
Other pruritus
8.0
31.4
72
91
A02BC05
ATC
esomeprazole; systemic
1.4
31.4
1940
15177
XQ820
NOMESCO Finland
Exposure to medicinal substance
13.2
31.3
55
42
M79.6
ICD-10 Finland
Pain in limb
1.4
31.2
1718
13144
G47.3
ICD-10 Finland
Sleep apnoea
1.6
30.7
880
5804
J30.4
ICD-10 Finland
Allergic rhinitis, unspecified
2.8
30.6
208
769
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.4
30.6
1875
14626
6925B
ICD-9 Finland
Contact dermatitis and other eczema, Due to food in contact with skin[DERMATITIS ARTEFACTA EX ALIMENTIS ALLERGICA,VÄLITÖN]
+∞
30.2
29
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
30.2
1797
13930
L26
ICD-10 Finland
Exfoliative dermatitis
304.0
29.8
30
*
D07AC03
ATC
desoximetasone; topical
4.5
29.7
108
245
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
1.5
29.7
1412
10465
M54.5
ICD-10 Finland
Low back pain
1.4
28.8
1622
12419
S21
ICPC
Skin texture symptom/complaint
1.8
28.5
551
3241
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
28.4
2348
19251
E0001A1
ATC
NA
3.2
27.9
149
470
WZC30
NOMESCO Finland
Teaching
1.7
27.9
589
3560
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.6
27.4
815
5411
R03BA08
ATC
ciclesonide; inhalant
1.9
27.4
416
2252
H01.0
ICD-10 Finland
Blepharitis
2.2
27.3
290
1358
L43.8
ICD-10 Finland
Other lichen planus
4.1
27.3
108
266
S01GX02
ATC
levocabastine; ophthalmic
2.0
26.8
338
1704
M03BX02
ATC
tizanidine; oral
1.4
26.7
3215
27929
L24.5
ICD-10 Finland
Irritant contact dermatitis due to other chemical products
97.2
26.7
29
*
XG474
NOMESCO Finland
Exhalation nntrogen oxide
2.9
26.5
170
607
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
1.5
26.2
1123
8111
R51.80
ICD-10 Finland
Headache
1.6
25.6
762
5056
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.8
25.6
454
2595
J01FA10
ATC
azithromycin; systemic
1.4
25.6
3112
26986
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.8
25.6
480
2795
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.7
25.5
556
3391
J01MA12
ATC
levofloxacin; systemic
1.6
25.4
745
4922
SPAT1283
SPAT
Restricted health certificate
1.5
25.4
1027
7320
R06AX18
ATC
acrivastine; oral
2.8
25.3
163
584
6929X
ICD-9 Finland
Contact dermatitis and other eczema, Unspecified cause[DERMATITITIS ARTEFACTA NUD]
+∞
25.0
24
*
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
1.8
24.8
442
2530
A07AA02
ATC
nystatin; oral
2.1
24.7
276
1322
L71.9
ICD-10 Finland
Rosacea, unspecified
3.2
24.7
132
418
S02
ICPC
Pruritus
2.7
24.7
171
640
H04.10
ICD-10 Finland
Dry eye syndrome
1.8
24.4
475
2793
T78.2
ICD-10 Finland
Anaphylactic shock, unspecified
4.6
24.3
85
186
L56.4
ICD-10 Finland
Polymorphous light eruption
11.0
24.3
46
42
69282
ICD-8 Finland
Other eczema and dermatitis, E microbis
+∞
24.0
23
*
J01FA06
ATC
roxithromycin; oral
1.4
23.7
1955
15866
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.4
23.5
1156
8562
6929B
ICD-9 Finland
Contact dermatitis and other eczema, Unspecified cause[ECZEMA INFECTIOSUM]
+∞
22.9
22
*
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.7
22.9
487
2945
R01AD12
ATC
fluticasone furoate; nasal
1.4
22.9
1556
12211
Z50.1
ICD-10 Finland
Other physical therapy
2.1
22.8
263
1278
J05AB01
ATC
aciclovir; systemic
1.5
22.7
1026
7461
J01MA02
ATC
ciprofloxacin; systemic
1.4
22.5
1638
12995
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.5
22.5
774
5307
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
22.4
1963
16044
L21.9
ICD-10 Finland
Seborrhoeic dermatitis, unspecified
4.7
22.3
77
167
S18
ICPC
Laceration/cut
1.4
22.1
1771
14263
SPAT1153
SPAT
Removal of sutures
1.4
21.9
1352
10418
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.6
21.6
591
3831
R03AC03
ATC
terbutaline; inhalant
1.6
21.5
662
4415
G44.2
ICD-10 Finland
Tension-type headache
1.6
21.5
671
4493
SPAT1301
SPAT
No procedures
1.4
21.5
1384
10736
A06AC01
ATC
ispaghula (psylla seeds); oral
1.4
21.4
1041
7676
J01FA09
ATC
clarithromycin; systemic
1.4
21.3
1583
12577
I83.1
ICD-10 Finland
Varicose veins of lower extremities with inflammation
3.5
21.3
102
298
R96
ICPC
Asthma
1.8
21.3
389
2243
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.4
20.9
1144
8617
J31.0
ICD-10 Finland
Chronic rhinitis
1.8
20.9
373
2135
J01CF05
ATC
flucloxacillin; systemic
2.4
20.8
178
750
L71.0
ICD-10 Finland
Perioral dermatitis
3.4
20.7
100
294
D05AX03
ATC
calcitriol; topical
4.1
20.5
81
201
R06AX26
ATC
fexofenadine; oral
1.8
20.5
355
2009
M01AH05
ATC
etoricoxib; oral
1.3
20.5
2912
25432
A02BC01
ATC
omeprazole; systemic
1.4
20.5
1173
8905
Z01.2
ICD-10 Finland
Dental examination
1.3
20.1
2058
17142
X59
ICD-10 Finland
Exposure to unspecified factor
1.5
20.0
789
5560
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
19.8
3665
33132
J01FA01
ATC
erythromycin; systemic
1.5
19.8
734
5105
R42
ICD-10 Finland
Dizziness and giddiness
1.5
19.8
882
6377
69299
ICD-8 Finland
Other eczema and dermatitis, Due to other and unspecified cause
+∞
19.8
19
*
UJF32
NOMESCO Finland
Coloscopy
1.4
19.6
1030
7687
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.5
19.3
680
4674
S06
ICPC
Rash localized
2.0
19.2
236
1178
P01AB01
ATC
metronidazole; oral, rectal
1.3
19.2
1980
16472
SAA02
NOMESCO Finland
Basic examination of mouth
1.3
19.2
3344
29903
SPAT1310
SPAT
Counselling related to known health issue
1.4
19.1
1445
11472
R03AK07
ATC
formoterol and budesonide; inhalant
1.4
19.1
889
6481
SPAT1260
SPAT
Consultation of another employee
1.5
19.1
771
5461
I83.0
ICD-10 Finland
Varicose veins of lower extremities with ulcer
3.4
18.9
92
273
N02AX02
ATC
tramadol; systemic, rectal
1.3
18.7
1804
14849
L17
ICPC
Foot/toe symptom/complaint
1.4
18.6
1092
8303
R05
ICPC
Cough
1.4
18.6
1015
7622
M01AE02
ATC
naproxen; oral, rectal
1.3
18.5
2846
24963
L43.9
ICD-10 Finland
Lichen planus, unspecified
3.5
18.5
87
252
N03AX16
ATC
pregabalin; oral
1.4
18.4
1006
7550
R02
ICPC
Shortness of breath/dyspnoea
1.6
18.4
475
3028
SPAT1059
SPAT
Spirometry at the office
2.0
18.4
225
1122
L04AD01
ATC
ciclosporin; systemic
3.2
18.3
97
307
X58
ICD-10 Finland
Exposure to other specified factors
1.5
18.3
592
3993
M79.1
ICD-10 Finland
Myalgia
1.5
17.9
599
4070
Z03.8
ICD-10 Finland
Observation for other suspected diseases and conditions
2.1
17.8
195
928
N03AX12
ATC
gabapentin; oral
1.5
17.8
666
4640
L30.4
ICD-10 Finland
Erythema intertrigo
5.3
17.8
54
103
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.0
17.8
244
1274
J20
ICD-10 Finland
Acute bronchitis
1.7
17.7
419
2609
69240
ICD-8 Finland
Other eczema and dermatitis, Due to other chemicals
+∞
17.7
17
*
SPAT1312
SPAT
General health counselling
1.3
17.7
1493
12030
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
17.6
1888
15739
D05AX02
ATC
calcipotriol; topical
2.3
17.5
165
734
SPAT1249
SPAT
Treatment-related counselling outside office
1.3
17.4
1872
15608
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
1.6
17.3
531
3534
XG410
NOMESCO Finland
Flow-volume spirometry
2.2
17.1
169
769
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.7
17.0
397
2459
M53.1
ICD-10 Finland
Cervicobrachial syndrome
1.5
17.0
535
3584
J01DB05
ATC
cefadroxil; oral
2.1
16.9
200
983
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.3
16.8
1212
9519
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.5
16.8
733
5268
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.3
16.8
2740
24089
S01BA01
ATC
dexamethasone; ophthalmic (corticosteroids, plain)
2.3
16.7
161
725
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.3
16.7
1522
12379
L24.3
ICD-10 Finland
Irritant contact dermatitis due to cosmetics
+∞
16.7
16
*
SHA02
NOMESCO Finland
Correction of physiology of bite - basic therapy visit
1.7
16.6
362
2204
395
Kela drug reimbursment
Dupilumab
90.3
16.6
18
*
L30
ICD-10 Finland
Other dermatitis
2.9
16.5
98
337
Z51.6
ICD-10 Finland
Desensitization to allergens
3.7
16.5
72
197
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.3
16.4
1785
14874
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.3
16.4
2625
22990
SHA03
NOMESCO Finland
Correction of physiology of bite - demanding therapy visit
2.2
16.4
169
785
SPAT1058
SPAT
PEF monitoring instruction
1.7
16.3
354
2151
L08.0
ICD-10 Finland
Pyoderma
5.1
16.3
51
101
M01AB05
ATC
diclofenac; systemic, rectal
1.3
16.3
3270
29448
D11
ICPC
Diarrhoea
1.5
16.2
533
3606
SPAT1211
SPAT
Application of soft bandage
1.7
16.2
372
2296
XQ817
NOMESCO Finland
NA
30.1
16.1
21
7
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
16.1
2380
20625
A02BC03
ATC
lansoprazole; oral
1.3
15.9
1241
9853
R03AK10
ATC
vilanterol and fluticasone furoate; inhalant
2.1
15.9
179
862
L03
ICPC
Low back symptom/complaint
1.4
15.9
1082
8410
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.7
15.8
367
2270
L01.1
ICD-10 Finland
Impetiginization of other dermatoses
7.7
15.8
36
47
H60.9
ICD-10 Finland
Otitis externa, unspecified
1.8
15.8
290
1675
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
15.6
2115
18102
M54.4
ICD-10 Finland
Lumbago with sciatica
1.4
15.6
731
5321
R05
ICD-10 Finland
Cough
1.4
15.6
825
6140
J01XC01
ATC
fusidic acid; systemic
3.4
15.5
75
224
H10.5
ICD-10 Finland
Blepharoconjunctivitis
2.9
15.4
92
318
SBB10
NOMESCO Finland
Teeth copy
1.8
15.4
285
1649
R21
ICPC
Throat symptom/complaint
1.4
15.3
1007
7780
M01AE03
ATC
ketoprofen; systemic, rectal
1.3
15.2
1636
13584
R74
ICPC
Upper respiratory infection acute
1.3
15.1
1460
11942
WQ021
NOMESCO Finland
NA
20.1
15.1
22
11
WQ020
NOMESCO Finland
NA
45.1
15.0
18
*
L40.8
ICD-10 Finland
Other psoriasis
5.5
15.0
44
81
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
1.7
15.0
303
1802
UJF30
NOMESCO Finland
Ileoscopy through colon
1.6
15.0
402
2582
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.4
15.0
962
7396
134
Kela drug reimbursment
General erythroderma
12.4
14.8
26
21
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
1.6
14.8
395
2536
R01BA52
ATC
pseudoephedrine, combinations; oral
1.3
14.8
1479
12148
A02BA02
ATC
ranitidine; systemic
1.4
14.6
761
5644
501
Kela drug reimbursment
Cow's milk and / or soy protein allergy in young children
5.7
14.6
41
72
H01
ICPC
Ear pain/earache
1.5
14.6
486
3295
S01GX05
ATC
lodoxamide; ophthalmic
3.1
14.6
80
262
C03CA01
ATC
furosemide; systemic
1.4
14.6
822
6185
SPAT1254
SPAT
Administration of medicine
1.5
14.5
549
3823
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.3
14.4
1382
11284
UDH02
NOMESCO Finland
Rhinopharyngoscopy
1.8
14.4
272
1586
A02BC04
ATC
rabeprazole; oral
1.6
14.3
379
2429
WQ000
NOMESCO Finland
Hyposensibilisation
5.7
14.3
40
70
L01
ICPC
Neck symptom/complaint
1.4
14.2
613
4386
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
1.8
14.1
263
1526
L25.8
ICD-10 Finland
Unspecified contact dermatitis due to other agents
42.6
14.1
17
*
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.4
14.1
722
5337
H01.1
ICD-10 Finland
Noninfectious dermatoses of eyelid
5.6
14.0
40
72
R53
ICD-10 Finland
Malaise and fatigue
1.4
13.9
831
6308
T78.3
ICD-10 Finland
Angioneurotic oedema
3.2
13.8
72
228
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
1.7
13.8
274
1621
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.5
13.8
456
3085
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
1.6
13.7
330
2063
D11AH05
ATC
dupilumab; topical
75.3
13.6
15
*
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
1.8
13.6
249
1440
6924D
ICD-9 Finland
Contact dermatitis and other eczema, Due to other chemical products[DERMATITIS ARTEFACTA E CHEMICALIBUS GUMMI ALLERGICA]
+∞
13.5
13
*
R01AD01
ATC
beclometasone; nasal
1.4
13.5
690
5098
A03
ICPC
Fever
1.4
13.5
751
5633
F29
ICPC
Eye symptom/complaint other
1.6
13.4
341
2165
K30
ICD-10 Finland
Functional dyspepsia
1.5
13.4
448
3037
R01AD11
ATC
triamcinolone; nasal
1.5
13.3
411
2736
R01AD05
ATC
budesonide; nasal
1.6
13.2
352
2259
R03BB04
ATC
tiotropium bromide; inhalant
1.7
13.1
298
1837
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.4
13.1
575
4125
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.3
13.0
1177
9506
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.6
13.0
380
2496
D01BA02
ATC
terbinafine; oral; topical
1.3
12.9
963
7570
L08
ICPC
Shoulder symptom/complaint
1.4
12.8
760
5758
S76
ICPC
Skin infection other
1.9
12.8
184
981
L08.8
ICD-10 Finland
Other specified local infections of skin and subcutaneous tissue
2.4
12.8
105
437
M03BC01
ATC
orphenadrine (citrate); systemic
1.3
12.8
1115
8959
H03AA01
ATC
levothyroxine sodium; systemic
1.3
12.7
1089
8725
N06AX21
ATC
duloxetine; oral
1.5
12.7
483
3368
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
2.0
12.7
158
799
J02AB02
ATC
ketoconazole; oral
2.1
12.6
139
666
XQ818
NOMESCO Finland
Conjunctival allergen provocation test
15.4
12.6
20
13
4930A
ICD-9 Finland
Asthma, Extrinsic asthma[EXTRINSIC ASTHMA SINE EXACERBATIONE]
3.5
12.5
58
169
I83.2
ICD-10 Finland
Varicose veins of lower extremities with both ulcer and inflammation
5.5
12.5
36
66
A05
ICPC
Feeling ill
1.7
12.5
260
1564
L12
ICPC
Hand/finger symptom/complaint
1.4
12.4
596
4349
M02AA07
ATC
piroxicam; topical
1.3
12.4
1514
12699
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.2
12.4
2848
25649
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
2.9
12.3
72
247
R03AC13
ATC
formoterol; inhalant
1.8
12.3
205
1149
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.3
12.3
1346
11140
L93.0
ICD-10 Finland
Discoid lupus erythematosus
7.1
12.2
29
41
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.2
12.2
2473
21959
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.3
12.2
1453
12144
T88.7
ICD-10 Finland
Unspecified adverse effect of drug or medicament
2.8
12.2
77
278
WX290
NOMESCO Finland
Other blockade of nerve
1.2
12.2
2213
19423
R03BA01
ATC
beclometasone; inhalant
1.4
12.1
584
4263
E66.01
ICD-10 Finland
Obesity due to excess calories
1.5
12.1
378
2521
K07.60
ICD-10 Finland
Snapping jaw
1.7
12.1
248
1485
S01AD03
ATC
aciclovir; ophthalmic
2.0
12.0
157
809
J30.0
ICD-10 Finland
Vasomotor rhinitis
2.3
11.9
112
502
L28
ICPC
Limited function/disability (L)
1.4
11.9
513
3667
SPAT1212
SPAT
Extensive examination of musculoskeletal system
1.6
11.9
345
2264
X57
ICD-10 Finland
Unspecified privation
2.5
11.9
90
361
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.3
11.8
934
7392
SPAT1262
SPAT
Handing over of treatment supplies
1.4
11.7
644
4810
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
2.3
11.7
107
473
L28.2
ICD-10 Finland
Other prurigo
16.4
11.6
18
11
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.0
11.6
152
783
QX_2
NOMESCO Finland
Other diagnostic procedures of skin
65.1
11.6
13
*
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
1.9
11.6
164
872
D01AC02
ATC
miconazole; topical
1.6
11.5
270
1679
WXQ24
NOMESCO Finland
UVB/UVA light therapy
+∞
11.5
11
*
XG405
NOMESCO Finland
Education on PEF monitoring
2.8
11.4
71
253
R52.9
ICD-10 Finland
Pain, unspecified
1.6
11.4
335
2207
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.6
11.4
280
1764
J05AB11
ATC
valaciclovir; oral
1.4
11.3
558
4086
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.5
11.3
402
2761
G01AF05
ATC
econazole; vaginal
1.5
11.3
416
2881
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.4
11.3
533
3877
L27.1
ICD-10 Finland
Localized skin eruption due to drugs and medicaments
8.3
11.3
24
29
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
2.7
11.2
74
273
H60.8
ICD-10 Finland
Other otitis externa
2.1
11.2
119
563
R60.0
ICD-10 Finland
Localized oedema
1.5
11.2
374
2538
B35.3
ICD-10 Finland
Tinea pedis
2.0
11.1
143
733
S61.0
ICD-10 Finland
Open wound of finger(s) without damage to nail
1.5
11.0
331
2193
R20.2
ICD-10 Finland
Paraesthesia of skin
1.6
11.0
292
1877
R06AX11
ATC
astemizole; oral
2.0
11.0
138
700
A10AE05
ATC
insulin detemir; parenteral
1.7
10.9
207
1210
Z00.0
ICD-10 Finland
General medical examination
1.3
10.8
732
5655
R06AE08
ATC
NA
3.2
10.7
55
174
C05AA08
ATC
fluocortolone; rectal, topical
1.4
10.7
569
4226
H29
ICPC
Ear symptom/complaint other
1.5
10.7
370
2528
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
1.8
10.7
172
954
V700A
ICD-9 Finland
General medical examination, Routine general medical examination at a health care facility
2.3
10.7
100
448
K02.1
ICD-10 Finland
Caries of dentine
1.2
10.7
2789
25278
L40.9
ICD-10 Finland
Psoriasis, unspecified
2.9
10.6
62
215
R05FA02
ATC
opium derivatives and expectorants; systemic
1.2
10.5
1845
16060
WX110
NOMESCO Finland
Local anesthesy
1.2
10.4
3421
31670
6918C
ICD-9 Finland
Atopic dermatitis and related conditions, Other atopic dermatitis and related conditions[DIATHESIS (CONSTITUTIO) ATOPICA]
+∞
10.4
10
*
6924L
ICD-9 Finland
Contact dermatitis and other eczema, Due to other chemical products[DERMATITIS ARTEFACTA E ODORIFERIS ALLERGICA]
+∞
10.4
10
*
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
2.5
10.4
78
314
R06.2
ICD-10 Finland
Wheezing
1.8
10.4
171
957
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.4
10.3
504
3685
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
2.3
10.3
96
430
L16
ICPC
Ankle symptom/complaint
1.5
10.3
411
2893
L01.0
ICD-10 Finland
Impetigo [any organism] [any site]
2.9
10.3
61
213
N02AJ06
ATC
codeine and paracetamol; systemic
1.2
10.3
1641
14133
G43.9
ICD-10 Finland
Migraine, unspecified
1.6
10.3
289
1887
C07AB07
ATC
bisoprolol; oral
1.2
10.2
1651
14238
I10
ICD-10 Finland
Essential (primary) hypertension
1.2
10.2
2058
18155
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
1.7
10.2
226
1386
XG480
NOMESCO Finland
Histamine provocation of respiratroy tract
2.6
10.2
73
286
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.3
10.2
1000
8138
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.4
10.1
458
3301
L56.8
ICD-10 Finland
Other specified acute skin changes due to ultraviolet radiation
13.1
10.1
17
13
L43.0
ICD-10 Finland
Hypertrophic lichen planus
5.0
10.1
31
62
Y57
ICD-10 Finland
Adverse effects in the therapeutic use of other and unspecified drugs and medicaments
2.4
10.1
83
350
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
1.5
10.1
325
2187
Z96.1
ICD-10 Finland
Presence of intraocular lens
1.5
10.1
341
2321
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.4
10.1
605
4584
M79.0
ICD-10 Finland
Rheumatism, unspecified
1.8
10.0
157
864
S99
ICPC
Skin disease other
2.5
10.0
75
301
F45.8
ICD-10 Finland
Other somatoform disorders
1.5
9.9
333
2260
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.2
9.9
1257
10546
D07XB01
ATC
flumetasone, combinations; topical
4.4
9.9
34
77
H10.0
ICD-10 Finland
Mucopurulent conjunctivitis
1.6
9.9
244
1540
K13.79
ICD-10 Finland
Change in the oral mucosa UNS
2.2
9.9
100
466
A01AB09
ATC
miconazole; local oral
1.5
9.9
341
2333
L21
ICD-10 Finland
Seborrhoeic dermatitis
3.0
9.8
53
175
49300
ICD-8 Finland
Asthma, bronchiale
2.3
9.8
87
382
4779A
ICD-9 Finland
Allergic rhinitis, Cause unspecified
3.4
9.8
45
132
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.6
9.8
270
1755
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
1.9
9.8
149
813
SPAT1104
SPAT
Monitoring of emergency patient
1.6
9.8
235
1474
S01GX04
ATC
nedocromil; ophthalmic
2.4
9.7
80
339
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.4
9.7
485
3565
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.2
9.7
1813
15856
S01GX09
ATC
olopatadine; ophthalmic
2.0
9.6
112
552
A77
ICPC
Viral disease other/NOS
1.8
9.6
159
896
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.3
9.5
811
6471
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
1.6
9.5
224
1396
J45.8
ICD-10 Finland
Mixed asthma
2.0
9.5
118
598
L29.0
ICD-10 Finland
Pruritus ani
4.0
9.5
36
90
SAA04
NOMESCO Finland
Special inverstigation of mouth
1.6
9.5
222
1383
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.3
9.5
714
5602
XCK10
NOMESCO Finland
Photography of fundus of eye
1.5
9.4
330
2261
L15
ICPC
Knee symptom/complaint
1.3
9.4
826
6615
H10.4
ICD-10 Finland
Chronic conjunctivitis
3.2
9.4
47
147
WX722
NOMESCO Finland
PEEP
1.8
9.4
158
894
S01GX08
ATC
ketotifen; ophthalmic
1.8
9.4
161
913
J01MA14
ATC
moxifloxacin; systemic
1.5
9.4
318
2164
J01CA04
ATC
amoxicillin; systemic
1.2
9.4
4157
39390
R01AC01
ATC
cromoglicic acid; nasal
1.7
9.4
174
1016
J45.1
ICD-10 Finland
Nonallergic asthma
1.6
9.4
256
1661
M03BC51
ATC
orphenadrine, combinations; systemic
1.2
9.3
1293
10945
L13.9
ICD-10 Finland
Bullous disorder, unspecified
5.3
9.3
27
51
R07.0
ICD-10 Finland
Pain in throat
1.6
9.3
263
1718
S01AA01
ATC
chloramphenicol; ophthalmic (antibiotics)
1.6
9.3
214
1328
SDA02
NOMESCO Finland
Parodonthologic therapy
1.2
9.3
1494
12848
L04AX01
ATC
azathioprine; systemic
1.8
9.3
166
958
F43.1
ICD-10 Finland
Post-traumatic stress disorder
2.0
9.3
121
627
K11.2
ICD-10 Finland
Sialoadenitis
1.9
9.2
129
685
S02CA02
ATC
flumetasone and antiinfectives; otic
1.6
9.2
211
1309
N06AB04
ATC
citalopram; systemic
1.3
9.2
910
7407
W22
ICD-10 Finland
Striking against or struck by other object(s)
1.6
9.1
225
1421
N01
ICPC
Headache
1.4
9.1
465
3426
D07AB09
ATC
triamcinolone; topical
4.3
9.1
32
75
XQ811
NOMESCO Finland
Exposure to latex
36.7
9.0
11
*
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.3
9.0
690
5426
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.4
9.0
526
3969
S01GX06
ATC
emedastine; ophthalmic
2.6
9.0
63
246
M79.7
ICD-10 Finland
Fibromyalgia
1.7
9.0
163
946
L57.8
ICD-10 Finland
Other skin changes due to chronic exposure to nonionizing radiation
7.4
8.9
20
27
J37.0
ICD-10 Finland
Chronic laryngitis
1.9
8.9
128
687
R03AK08
ATC
formoterol and beclometasone; inhalant
1.8
8.9
147
828
R03AC12
ATC
salmeterol; inhalant
1.8
8.8
147
829
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
1.8
8.8
143
799
UDM02
NOMESCO Finland
Sinoscopy
2.2
8.8
90
422
SXC05
NOMESCO Finland
Other oral or dental procedure
1.6
8.8
240
1559
R07.4
ICD-10 Finland
Chest pain, unspecified
1.3
8.7
970
7999
L70.0
ICD-10 Finland
Acne vulgaris
2.0
8.7
110
562
S60.2
ICD-10 Finland
Contusion of other parts of wrist and hand
1.7
8.7
188
1147
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
1.3
8.7
856
6956
L73.8
ICD-10 Finland
Other specified follicular disorders
3.7
8.7
36
98
TPH04
NOMESCO Finland
Cathetrisation of vein
1.3
8.6
757
6061
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
1.5
8.6
269
1802
K52.2
ICD-10 Finland
Allergic and dietetic gastroenteritis and colitis
5.0
8.6
26
52
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
1.6
8.6
203
1270
R29
ICPC
Respiratory symptom/complaint other
1.6
8.5
242
1582
RJ411
NOMESCO Finland
NA
4.4
8.5
29
66
SPAT1216
SPAT
Assessment of functional ability
1.4
8.5
481
3612
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
2.2
8.5
83
383
R07.3
ICD-10 Finland
Other chest pain
1.5
8.5
318
2213
H60
ICD-10 Finland
Otitis externa
1.7
8.5
187
1147
L50
ICD-10 Finland
Urticaria
2.3
8.4
74
324
L24.1
ICD-10 Finland
Irritant contact dermatitis due to oils and greases
90.2
8.4
9
*
M72.2
ICD-10 Finland
Plantar fascial fibromatosis
1.5
8.4
318
2218
L04AA01
ATC
[U] ciclosporin; systemic
2.6
8.3
57
217
PD4DE
NOMESCO Finland
Lower extremity artery ultrasound examination with Doppler method
2.9
8.3
48
165
6924N
ICD-9 Finland
Contact dermatitis and other eczema, Due to other chemical products[DERMATITIS ARTEFACTA E CHEMICALIBUS ALIIS ALLERGICA]
+∞
8.3
8
*
6928B
ICD-9 Finland
Contact dermatitis and other eczema, Due to other specified agents[DERMATITIS ARTEFACTA E COSMETICA ALLERGICA]
+∞
8.3
8
*
S01
ICPC
Pain/tenderness of skin
1.7
8.3
150
870
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.2
8.3
1136
9585
H66.9
ICD-10 Finland
Otitis media, unspecified
1.5
8.3
238
1560
Z71.9
ICD-10 Finland
Counselling, unspecified
1.6
8.3
224
1448
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.3
8.3
551
4241
R00.2
ICD-10 Finland
Palpitations
1.5
8.3
297
2046
S80.0
ICD-10 Finland
Contusion of knee
1.5
8.3
268
1810
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.2
8.3
2003
17873
L50.5
ICD-10 Finland
Cholinergic urticaria
10.7
8.3
15
14
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.4
8.3
378
2735
R01AC02
ATC
levocabastine; nasal
1.9
8.3
123
670
K07.63
ICD-10 Finland
Pain in the jaw joint UNS
2.1
8.3
84
395
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
1.6
8.2
220
1419
L50.1
ICD-10 Finland
Idiopathic urticaria
3.5
8.2
36
103
J34.2
ICD-10 Finland
Deviated nasal septum
1.6
8.2
183
1129
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.2
8.2
1082
9097
M77.0
ICD-10 Finland
Medial epicondylitis
1.9
8.2
106
549
R05FB02
ATC
cough suppressants and expectorants
1.2
8.2
1603
14025
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.4
8.1
403
2960
R03AK11
ATC
formoterol and fluticasone; inhalant
2.0
8.1
99
501
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
1.4
8.1
392
2863
R09
ICPC
Sinus symptom/complaint
1.4
8.1
347
2480
L08.9
ICD-10 Finland
Local infection of skin and subcutaneous tissue, unspecified
2.0
8.1
97
488
103
Kela drug reimbursment
Diabetes, insulin-treated
1.3
8.1
842
6884
D73
ICPC
Gastroenteritis presumed infection
1.8
8.1
129
721
R51
ICD-10 Finland
Headache
1.6
8.0
223
1454
WX408
NOMESCO Finland
General anesthesy, balanced
1.2
8.0
1082
9112
R13
ICD-10 Finland
Dysphagia
1.6
8.0
204
1302
M19.0
ICD-10 Finland
Primary arthrosis of other joints
1.4
8.0
336
2390
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
1.6
8.0
181
1118
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
1.5
8.0
239
1585
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.4
8.0
364
2631
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
1.8
8.0
139
797
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
1.7
7.9
172
1051
A04
ICPC
Weakness/tiredness general
1.3
7.9
472
3575
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.3
7.9
567
4412
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
1.5
7.9
266
1810
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.2
7.9
1201
10244
C08CA01
ATC
amlodipine; oral
1.2
7.9
1132
9595
I84.9
ICD-10 Finland
Unspecified hemorrhoids without complication
1.6
7.9
178
1103
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
1.9
7.9
108
574
SHA01
NOMESCO Finland
Correction of physiology of bite - simple therapy visit
1.3
7.8
485
3694
M54
ICD-10 Finland
Dorsalgia
1.4
7.8
451
3397
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.3
7.8
469
3553
M53.2
ICD-10 Finland
Spinal instabilities
3.1
7.8
41
135
R51.81
ICD-10 Finland
Facial pain NOS
2.0
7.8
97
497
M01AE01
ATC
ibuprofen; systemic, rectal
1.2
7.8
4699
45340
M70.6
ICD-10 Finland
Trochanteric bursitis
1.3
7.8
471
3574
K90.0
ICD-10 Finland
Coeliac disease
1.8
7.8
119
656
ACC51
NOMESCO Finland
Release of median nerve
1.5
7.8
296
2067
SBA00
NOMESCO Finland
Microbiological examinations
2.0
7.7
90
449
C09CA06
ATC
candesartan; oral
1.3
7.7
835
6855
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
1.5
7.7
254
1721
J32.2
ICD-10 Finland
Chronic ethmoidal sinusitis
3.0
7.7
41
136
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
1.6
7.7
213
1386
DHB50
NOMESCO Finland
Turbinoplasty
1.9
7.7
106
561
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
1.6
7.7
178
1110
N05CF01
ATC
zopiclone; oral
1.2
7.7
1222
10465
C07AA05
ATC
propranolol; systemic
1.3
7.7
855
7045
J01CE08
ATC
benzathine benzylpenicillin; parenteral
3.4
7.7
35
104
S06.0
ICD-10 Finland
Concussion
1.4
7.7
388
2857
TQX05
NOMESCO Finland
Skin puncture, unspecified location
5.9
7.7
20
34
NH1BA
NOMESCO Finland
Ankle extensive X-ray examination
1.9
7.7
106
564
S97
ICPC
Chronic ulcer skin
1.7
7.6
142
833
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.2
7.6
2502
22864
B01AC04
ATC
clopidogrel; oral
1.4
7.6
383
2820
SPAT1257
SPAT
Teaching of medicine inhalation technique
1.8
7.6
119
661
R4120
NOMESCO Finland
Occupational therapy
1.5
7.6
231
1539
L25.3
ICD-10 Finland
Unspecified contact dermatitis due to other chemical products
25.0
7.6
10
*
H04AA01
ATC
glucagon; nasal, parenteral
1.9
7.6
101
530
UKC02
NOMESCO Finland
Cystoscopy
1.4
7.6
443
3346
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
1.9
7.5
101
531
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
1.4
7.5
414
3091
Z03
ICD-10 Finland
Medical observation and evaluation for suspected diseases and conditions, ruled out
1.4
7.5
299
2108
B35.1
ICD-10 Finland
Tinea unguium
1.6
7.5
184
1162
K59.0
ICD-10 Finland
Constipation
1.6
7.5
173
1078
J01EA01
ATC
trimethoprim; systemic
1.2
7.5
1101
9351
N06AX11
ATC
mirtazapine; oral
1.2
7.5
1330
11518
L03.1
ICD-10 Finland
Cellulitis of other parts of limb
2.0
7.4
87
433
D01AE15
ATC
terbinafine; topical
1.5
7.4
225
1499
L25.0
ICD-10 Finland
Unspecified contact dermatitis due to cosmetics
80.2
7.4
8
*
WXQ26
NOMESCO Finland
UVB broad spectrum light therapy
80.2
7.4
8
*
R52.2
ICD-10 Finland
Other chronic pain
1.8
7.4
123
694
B86
ICD-10 Finland
Scabies
2.3
7.4
65
287
M75.9
ICD-10 Finland
Shoulder lesion, unspecified
1.6
7.4
170
1058
C07AB02
ATC
metoprolol; systemic
1.3
7.4
633
5050
S93.4
ICD-10 Finland
Sprain and strain of ankle
1.3
7.4
444
3366
R5140
NOMESCO Finland
Monitoring the use of the aid
1.4
7.4
338
2446
E66.00
ICD-10 Finland
Metabolic syndrome
1.6
7.4
189
1211
L25
ICD-10 Finland
Unspecified contact dermatitis
5.3
7.4
21
40
H60.3
ICD-10 Finland
Other infective otitis externa
2.0
7.4
84
414
K12.18
ICD-10 Finland
Other forms of stomatitis
3.6
7.3
31
87
L28
ICD-10 Finland
Lichen simplex chronicus and prurigo
3.6
7.3
31
87
L24.2
ICD-10 Finland
Irritant contact dermatitis due to solvents
+∞
7.3
7
*
6923B
ICD-9 Finland
Contact dermatitis and other eczema, Due to drugs and medicines in contact with skin[DERMATITIS ARTEFACTA E PHARMACIS ALLERGICA]
+∞
7.3
7
*
6925D
ICD-9 Finland
Contact dermatitis and other eczema, Due to food in contact with skin[DERMATITIS ARTEFAC.EX ALIMENTIS ALLERG,VIIVÄSTYNYT]
+∞
7.3
7
*
XQ805
NOMESCO Finland
Photopatchtest of photoallergen
+∞
7.3
7
*
M07.3*L40.5
ICD-10 Finland
Other psoriatic arthropathies
2.0
7.3
86
431
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
1.5
7.3
241
1636
K59.1
ICD-10 Finland
Functional diarrhoea
1.6
7.3
183
1168
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
2.3
7.2
66
295
L13
ICPC
Hip symptom/complaint
1.3
7.2
548
4298
NG1BA
NOMESCO Finland
Knee extensive X-ray examination
2.1
7.2
74
350
S74
ICPC
Dermatophytosis
2.2
7.2
66
296
A01
ICPC
Pain general/multiple sites
1.5
7.2
268
1867
PH2DE
NOMESCO Finland
Ultrasound examination of bloodflow in veins of lower extremity with Doppler method
1.9
7.2
106
575
S01AA02
ATC
chlortetracycline; ophthalmic
3.3
7.2
33
99
L53.9
ICD-10 Finland
Erythematous condition, unspecified
2.7
7.2
44
161
R03DA04
ATC
theophylline; systemic, rectal
1.7
7.2
141
843
Z57.3
ICD-10 Finland
Occupational exposure to other air contaminants
4.1
7.2
26
64
R31
ICD-10 Finland
Unspecified haematuria
1.5
7.1
238
1619
M01AH01
ATC
celecoxib; oral (coxibs)
1.3
7.1
695
5636
K12.00
ICD-10 Finland
Recurrent oral aphthae
2.4
7.1
57
241
EMB10
NOMESCO Finland
Tonsillectomy
1.5
7.1
262
1820
H57.1
ICD-10 Finland
Ocular pain
1.7
7.1
128
746
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.4
7.1
319
2307
A06AD11
ATC
lactulose; oral
1.3
7.1
417
3152
A07EC02
ATC
mesalazine; oral, rectal
1.5
7.0
207
1370
M94.0
ICD-10 Finland
Chondrocostal junction syndrome [Tietze]
1.9
7.0
97
517
SPAT1097
SPAT
Recording of ECG
1.3
7.0
488
3782
H25.8
ICD-10 Finland
Other senile cataract
1.5
7.0
264
1844
D01
ICPC
Abdominal pain/cramps general
1.3
7.0
428
3255
D10AX03
ATC
azelaic acid; topical
1.4
7.0
345
2530
H66.0
ICD-10 Finland
Acute suppurative otitis media
1.5
7.0
258
1794
H70
ICPC
Otitis externa
2.1
7.0
77
376
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
1.4
7.0
370
2747
N76.0
ICD-10 Finland
Acute vaginitis
1.4
7.0
273
1920
Z04.3
ICD-10 Finland
Examination and observation following other accident
2.0
7.0
81
403
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.3
6.9
508
3963
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.3
6.9
668
5407
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.4
6.9
364
2703
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
1.4
6.9
340
2496
LCA13
NOMESCO Finland
Curettage of cervix and body of uterus
1.5
6.9
238
1630
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
1.6
6.9
160
1000
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
1.5
6.9
229
1557
D06BB03
ATC
aciclovir; topical
1.5
6.9
199
1310
L03.0
ICD-10 Finland
Cellulitis of finger and toe
1.5
6.9
255
1773
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
1.7
6.9
145
884
EKA10
NOMESCO Finland
Biopsy of cheek
2.0
6.9
78
385
M01AC06
ATC
meloxicam; systemic, rectal
1.2
6.9
1573
13919
J01DA08
ATC
[U] cefaclor; oral
1.3
6.8
511
4001
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.4
6.8
310
2241
A10BA02
ATC
metformin; oral
1.2
6.8
868
7257
SPAT1238
SPAT
Brief therapy
1.9
6.8
89
467
OAA65
SPAT
NA
1.3
6.8
442
3396
XQ806
NOMESCO Finland
Minimal Erythema Dose (MED) test
40.1
6.8
8
*
RS340
NOMESCO Finland
NA
5.3
6.8
19
36
J01.9
ICD-10 Finland
Acute sinusitis, unspecified
1.6
6.7
152
944
J01CE02
ATC
phenoxymethylpenicillin; oral
1.2
6.7
3420
32206
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prothetic work
1.7
6.7
143
875
SDA03
NOMESCO Finland
Demanding parodonthologic therapy
1.2
6.7
1662
14797
H01.9
ICD-10 Finland
Inflammation of eyelid, unspecified
2.4
6.7
52
218
H10
ICD-10 Finland
Conjunctivitis
1.5
6.7
245
1701
XQ845
NOMESCO Finland
Dermatoscopy
2.7
6.6
43
161
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
2.0
6.6
77
386
DFF00
NOMESCO Finland
Pure tone audiometry
1.4
6.6
295
2130
L43.3
ICD-10 Finland
Subacute (active) lichen planus
5.9
6.6
17
29
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
1.5
6.6
247
1724
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.3
6.6
667
5434
M54.2
ICD-10 Finland
Cervicalgia
1.4
6.6
275
1963
Z02.7
ICD-10 Finland
Issue of medical certificate
1.5
6.6
209
1411
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
1.8
6.6
99
546
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.3
6.5
702
5754
L02
ICPC
Back symptom/complaint
1.4
6.5
358
2676
J01DA06
ATC
[U] cefuroxime; systemic
1.3
6.5
601
4837
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.4
6.5
307
2236
R60.9
ICD-10 Finland
Oedema, unspecified
1.6
6.5
154
967
R03CC02
ATC
salbutamol; systemic
1.5
6.5
234
1623
D07XB02
ATC
triamcinolone, combinations; topical
2.3
6.5
58
259
D82
ICPC
Teeth/gum disease
1.2
6.4
1580
14043
H43.8
ICD-10 Finland
Other disorders of vitreous body
1.4
6.4
302
2201
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.4
6.4
319
2344
SPAT1014
SPAT
Treatment of eyes
2.3
6.4
56
249
K13.74
ICD-10 Finland
Lichen rubs planus in the mouth
2.3
6.4
55
241
D01AC03
ATC
econazole; topical
1.5
6.4
201
1352
A07EA06
ATC
budesonide; oral, local oral
1.7
6.4
125
748
EBA10
NOMESCO Finland
Surgical removal of tooth
1.3
6.4
508
4015
XCK00
NOMESCO Finland
Perimetry
1.5
6.4
211
1436
G50.1
ICD-10 Finland
Atypical facial pain
2.0
6.4
75
379
G03DA02
ATC
medroxyprogesterone; systemic (pregnen (4) derivatives)
1.4
6.4
358
2689
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.2
6.4
758
6292
W19
ICD-10 Finland
Unspecified fall
1.4
6.3
314
2306
NF1AA
NOMESCO Finland
Hip X-ray examination
1.4
6.3
248
1744
F17.29
ICD-10 Finland
Addiction caused by tobacco UNS
2.1
6.3
63
297
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
1.5
6.3
194
1298
D06
ICPC
Abdominal pain localized other
1.4
6.3
315
2319
F03
ICPC
Eye discharge
1.4
6.3
242
1698
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
1.5
6.3
229
1588
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
1.4
6.3
256
1816
L29.2
ICD-10 Finland
Pruritus vulvae
2.6
6.3
43
169
T78.0
ICD-10 Finland
Anaphylactic shock due to adverse food reaction
5.9
6.3
16
27
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
1.6
6.3
160
1027
J01
ICD-10 Finland
Acute sinusitis
1.5
6.3
207
1409
M67.4
ICD-10 Finland
Ganglion
1.4
6.3
254
1799
M54.8
ICD-10 Finland
Other dorsalgia
1.6
6.3
158
1009
L13.0
ICD-10 Finland
Dermatitis herpetiformis
4.6
6.3
20
44
XQ812
NOMESCO Finland
Contact urticaria assay
18.0
6.3
9
5
6931A
ICD-9 Finland
Dermatitis due to substances taken internally, Due to food
+∞
6.2
6
*
I20.90
ICD-10 Finland
Angina pectoris, unspecified
1.9
6.2
82
430
E03
ICD-10 Finland
Other hypothyroidism
1.5
6.2
221
1528
N30.0
ICD-10 Finland
Acute cystitis
1.3
6.2
548
4387
H60.5
ICD-10 Finland
Acute otitis externa, noninfective
2.6
6.2
42
164
L10
ICPC
Elbow symptom/complaint
1.6
6.2
167
1086
L04.0
ICD-10 Finland
Acute lymphadenitis of face, head and neck
2.5
6.2
44
174
UDQ12
NOMESCO Finland
Flexible laryngoscopy
1.5
6.2
191
1281
C10AA07
ATC
rosuvastatin; oral
1.2
6.2
791
6614
B00.10
ICD-10 Finland
Herpes simplex facialis
2.8
6.2
36
128
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
1.4
6.1
269
1933
C05AA01
ATC
hydrocortisone; rectal, topical
1.5
6.1
180
1193
SDA01
NOMESCO Finland
Simple parodonthologic therapy
1.2
6.1
1127
9767
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
1.6
6.1
147
928
Z11.3
ICD-10 Finland
Special screening examination for infections with a predominantly sexual mode of transmission
1.4
6.1
251
1786
B00.19
ICD-10 Finland
Other vesicular dermatitis caused by the herper simplex virus
3.3
6.1
28
85
Y83.9
ICD-10 Finland
Surgical procedure, unspecified as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.8
6.1
99
559
Z00.8
ICD-10 Finland
Other general examinations
1.4
6.1
255
1820
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
1.8
6.1
93
514
H02AB09
ATC
hydrocortisone; systemic
1.9
6.1
85
455
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
1.5
6.1
175
1155
SPAT1255
SPAT
Intravenous administration of medicine
1.5
6.1
205
1403
K13.29
ICD-10 Finland
Indefinite leukoplakia
2.6
6.1
41
160
H04.5
ICD-10 Finland
Stenosis and insufficiency of lacrimal passages
2.0
6.1
73
373
NGA30
NOMESCO Finland
Exploration of knee joint, arthroscopic
1.5
6.1
185
1236
R32
ICD-10 Finland
Unspecified urinary incontinence
1.8
6.1
95
533
C10AC01
ATC
colestyramine; oral
1.8
6.0
94
523
WZA90
NOMESCO Finland
Other doctors statement
1.2
6.0
959
8199

Mortality – FinRegistry

Association

Association between endpoint L12_ALLERGICCONTACT and mortality.

Females

Parameter HR [95% CI] p-value
L12_ALLERGICCONTACT 0.967 [0.87, 1.07] 0.537
Birth year 0.991 [0.98, 1.0] 0.041

During the follow-up period (1.1.1998 — 31.12.2019), 1885 out of 27327 females with L12_ALLERGICCONTACT died.

Males

Parameter HR [95% CI] p-value
L12_ALLERGICCONTACT 1.022 [0.92, 1.14] 0.698
Birth year 0.987 [0.98, 1.0] 0.011

During the follow-up period (1.1.1998 — 31.12.2019), 1054 out of 10081 males with L12_ALLERGICCONTACT died.

Mortality risk

Mortality risk for people of age

years, who have L12_ALLERGICCONTACT.

N-year risk Females Males
1 0.078% 0.198%
5 0.533% 1.186%
10 1.338% 2.921%
15 2.52% 5.536%
20 4.343% 9.566%

Relationships between endpoints

Index endpoint: L12_ALLERGICCONTACT – Allergic contact dermatitis

GWS hits: 6

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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