No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
121 |
4. Check minimum number of eventsNone |
121 |
5. Include endpointsNone |
121 |
6. Filter based on genotype QC (FinnGen only) |
121 |
Control definitions (FinnGen only)
- Control exclude
- G6_AUTONOM
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- G90
- Name in latin
- Neuropathia autonomica peripherica idiopathica
Similar endpoints
↥List of similar endpoints to
Idiopathic peripheral autonomic neuropathy
based on the number of shared cases.
Similar with more cases:
- Autonomic disorders
- Other neurological diseases
- Neurological diseases
- Neurological diseases, wide definition
- Any operation in hilmo
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 941 | 432 | 497 |
| Only index persons | 774 | 372 | 402 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.01 | 0.01 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 57.97 | 60.25 | 55.86 |
| Only index persons | 55.19 | 57.82 | 52.76 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 121 | 61 | 60 |
| Unadjusted period prevalence (%) | 0.02 | 0.02 | 0.03 |
| Median age at first event (years) | 62.44 | 59.91 | 65.02 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 109
- Matched controls
- 1087
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G90.0
ICD-10 Finland
Idiopathic peripheral autonomic neuropathy
+∞
154.2
108
*
R55
ICD-10 Finland
Syncope and collapse
11.2
21.3
44
62
I49.5
ICD-10 Finland
Sick sinus syndrome
19.3
12.2
18
11
AA1AD
NOMESCO Finland
CT of head and brain
3.8
8.6
44
165
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
6.7
7.7
19
33
FPE20
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with atrial and ventricular electrodes
8.7
6.9
14
18
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
5.6
6.1
17
35
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
78
477
2.79
6.77
5.9
6.7
mmol/l
1.2
1.2
0.35
68
393
(3018418) pH of Serum or Plasma
56
292
2.71
6.65
3.3
4.0
ph
7.4
7.4
0.13
12
57
(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma
71
435
2.53
5.83
5.7
5.3
mmol/l
1.2
1.2
0.45
65
376
(3032080) INR in Blood by Coagulation assay
64
382
2.43
5.45
7.1
8.2
inr
1.2
1.2
0.17
17
119
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
57
343
2.25
4.55
3.8
3.5
—
—
—
0
0
(3023368) Bacteria identified in Blood by Culture
46
253
2.32
4.54
3.5
4.3
—
—
—
0
0
(3014765) Yersinia sp identified in Stool by Organism specific culture
11
26
4.55
4.46
1.4
1.3
—
—
—
0
0
(42529406) Shigella sp [Presence] in Stool by Culture
11
26
4.55
4.46
1.4
1.3
—
—
—
0
0
(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma
9
13
7.38
4.24
1.9
1.6
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
24
101
2.72
4.14
1.8
1.7
—
—
—
0
0
(3004588) Protein electrophoresis panel - Serum or Plasma
17
62
3.03
3.77
2.7
2.5
—
—
—
0
0
(3019309) Folate [Moles/volume] in Red Blood Cells
35
186
2.24
3.65
1.8
1.8
nmol/l
1168.5
1201.7
0.07
28
139
(3022948) Iron [Moles/volume] in Serum or Plasma
30
151
2.31
3.55
2.5
2.7
umol/l
14.9
13.0
0.44
30
139
(40758558) Short blood count panel - Blood
42
243
2.12
3.54
8.9
6.3
—
—
—
0
0
(3004789) Transferrin [Mass/volume] in Serum or Plasma
28
137
2.36
3.53
2.3
2.8
g/l
2.4
2.3
0.51
28
124
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
30
152
2.29
3.49
2.3
2.9
e6/l
1.1
1.3
0.16
20
89
(3037522) Nuclear Ab [Titer] in Serum
25
118
2.41
3.40
1.4
1.3
titre
413.3
487.5
—
6
32
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
36
202
2.11
3.25
2.6
2.0
—
—
—
0
0
(3013742) Prealbumin [Mass/volume] in Serum or Plasma
20
88
2.52
3.14
2.4
2.4
g/l
0.2
0.2
0.05
20
83
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
33
184
2.09
3.01
3.4
3.3
ng/l
42.2
121.4
0.84
26
145
(36304419) Bacteria [Presence] in Urine
43
267
1.95
2.91
3.2
3.1
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
15
60
2.71
2.83
1.7
1.8
—
—
—
0
0
(3042111) Morphology [Interpretation] in Bone marrow Narrative
7
14
5.23
2.77
2.9
1.4
—
—
—
0
0
(3014702) Chromogranin A [Moles/volume] in Serum or Plasma
6
10
6.24
2.73
3.2
3.6
nmol/l
2.8
3.1
—
6
10
(3004716) Salmonella sp identified in Stool by Organism specific culture
13
49
2.85
2.72
1.3
1.4
—
—
—
0
0
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
55
378
1.83
2.68
4.3
3.8
ng/l
20.9
37.1
1.57
38
274
(3045142) Bone marrow Pathology biopsy report
5
7
7.39
2.57
2.6
1.3
—
—
—
0
0
(3035637) Corticotropin [Mass/volume] in Plasma
5
7
7.39
2.57
1.8
2.0
—
—
—
0
0
(3018677) aPTT in Platelet poor plasma by Coagulation assay
27
148
2.06
2.55
2.6
1.8
s
28.6
29.5
0.49
27
141
(3006418) Campylobacter sp identified in Tissue by Organism specific culture
9
26
3.65
2.54
1.2
1.3
—
—
—
0
0
(42870588) Differential panel, method unspecified - Blood
47
314
1.81
2.48
8.5
4.5
—
—
—
0
0
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
54
379
1.77
2.40
2.7
2.0
pmol/l
94.9
93.2
0.10
38
184
(3024561) Albumin [Mass/volume] in Serum or Plasma
59
428
1.74
2.31
3.8
4.3
g/l
35.3
35.4
0.04
54
403
(4035726)
18
87
2.26
2.31
1.2
1.3
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
43
285
1.79
2.30
3.6
2.2
—
—
—
0
0
(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection
6
13
4.79
2.30
1.0
1.5
—
—
—
0
0
(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection
6
13
4.79
2.30
1.0
1.5
—
—
—
0
0
(40760888) Immunoglobulin light chains.free panel - Serum
6
15
4.15
2.06
6.2
3.5
—
—
—
0
0
(3018095) Leukocytes [#/volume] in Urine
49
348
1.69
2.01
3.6
4.1
e6/l
38.5
82.0
0.74
33
259
(3037467) Urinalysis macro (dipstick) panel - Urine
78
627
1.69
1.98
5.4
4.2
—
—
—
0
0
(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay
8
27
3.10
1.97
2.4
1.9
—
—
—
0
0
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
25
146
1.90
1.97
2.3
3.3
e6/l
10.1
2.7
0.71
15
83
(3044290) Cell count panel - Cerebral spinal fluid
6
16
3.89
1.96
1.2
1.1
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
23
131
1.93
1.95
1.5
2.0
—
—
—
0
0
(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum
9
34
2.78
1.91
1.1
1.0
—
—
—
0
0
(40761535) Cells panel - Urine sediment
15
73
2.20
1.90
8.7
4.0
—
—
—
0
0
(3027945) Reticulocytes/100 erythrocytes in Blood
21
117
1.96
1.89
6.0
2.5
%
1.7
1.7
0.07
21
104
(3028707) Methadone [Presence] in Urine by Screen method
6
17
3.66
1.86
2.0
1.6
—
—
—
0
0
(3020044) Glucose [Moles/volume] in Cerebral spinal fluid
6
18
3.45
1.77
1.2
1.2
mmol/l
3.5
3.5
—
6
18
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
24
144
1.83
1.74
1.9
1.8
—
—
—
0
0
(3019225) pH of Specimen
16
83
2.07
1.74
4.1
4.6
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
14
69
2.16
1.72
1.2
1.1
—
—
—
0
0
(3007164) IgA [Mass/volume] in Serum or Plasma
31
202
1.72
1.71
2.0
1.3
g/l
1.6
2.4
2.88
17
113
(3021589) Normoblasts [#/volume] in Blood
56
426
1.59
1.69
11.7
9.6
e9/l
0.0
0.0
0.38
50
345
(3030467) Casts [#/volume] in Urine by Automated count
39
272
1.64
1.67
3.4
3.3
e6/l
0.4
0.4
0.09
27
211
(3013139) Helicobacter pylori Ag [Presence] in Stool
12
56
2.27
1.67
1.1
1.3
—
—
—
0
0
(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence
5
14
3.68
1.63
1.2
1.1
—
—
—
0
0
(3022621) pH of Urine by Test strip
12
57
2.23
1.61
1.9
2.3
—
—
—
0
0
(3011288) Drugs identified in Urine by Screen method
7
26
2.79
1.60
3.6
1.9
—
—
—
0
0
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
7
26
2.79
1.60
1.4
1.3
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
21
329
0.56
1.59
2.5
3.0
—
—
—
0
0
(3043109) Cytology report of Tissue fine needle aspirate Cyto stain
5
15
3.43
1.54
1.0
1.4
—
—
—
0
0
(3004616) Nuclear Ab [Presence] in Serum
5
15
3.43
1.54
1.8
1.1
—
—
—
0
0
(3000991) Gas panel - Venous blood
15
80
2.00
1.52
6.9
6.4
—
—
—
0
0
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
17
95
1.92
1.52
4.4
3.6
—
—
—
0
0
(3015377) Calcium [Moles/volume] in Serum or Plasma
44
323
1.57
1.51
2.8
3.3
mmol/l
2.3
2.4
1.27
37
280
(3005322) IgE [Units/volume] in Serum or Plasma
10
45
2.33
1.51
1.4
1.3
u/ml
62.9
165.7
—
10
40
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
55
426
1.53
1.49
3.5
4.0
—
—
—
0
0
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
23
144
1.74
1.45
1.6
1.3
u/ml
1.1
6.9
1.15
12
60
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
104
934
1.81
1.45
20.8
14.4
mg/l
21.6
24.6
0.51
92
726
(3000850) Epithelial cells [#/volume] in Urine
32
220
1.62
1.44
3.0
2.8
e6/l
4.0
5.0
0.29
27
196
(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma
24
153
1.71
1.43
1.7
1.2
iu/ml
20.2
35.7
—
9
45
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
9
41
2.29
1.40
3.8
2.0
—
—
—
0
0
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
30
206
1.61
1.35
1.9
1.7
mg/l
1.3
0.9
0.50
20
168
(3026782) Osmolality of Urine
29
198
1.61
1.34
2.8
3.0
mosm/kgh2o
522.9
538.5
0.13
21
173
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
10
48
2.18
1.32
2.0
1.5
—
—
—
0
0
(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
5
18
2.85
1.30
1.0
1.6
—
—
—
0
0
(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing
5
18
2.85
1.30
1.2
1.3
—
—
—
0
0
(3003458) Phosphate [Moles/volume] in Serum or Plasma
20
126
1.70
1.24
5.2
6.6
mmol/l
1.1
1.1
0.64
20
116
(3013512) EKG study
37
272
1.52
1.24
3.4
4.1
—
—
—
0
0
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
8
37
2.24
1.24
1.5
1.6
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
19
118
1.72
1.24
1.2
1.3
—
—
—
0
0
(4010399)
12
64
1.97
1.23
1.2
1.3
—
—
—
0
0
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
6
26
2.37
1.20
1.0
1.7
—
—
—
0
0
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
6
26
2.37
1.20
1.0
1.7
—
—
—
0
0
(3015736) pH of Urine
45
348
1.47
1.18
5.5
3.7
—
—
—
0
0
(3002582) Erythrocytes [#/volume] in Urine
40
304
1.47
1.14
3.4
3.5
e6/l
11.7
284.3
0.73
29
243
(3037756) Immunofixation for Serum or Plasma
5
21
2.44
1.10
2.2
1.3
—
—
—
0
0
(3019550) Sodium [Moles/volume] in Serum or Plasma
104
956
1.63
1.04
22.4
16.6
mmol/l
139.4
139.7
0.45
104
928
(3011397) Hemoglobin [Presence] in Urine by Test strip
29
210
1.50
1.03
6.7
3.5
—
—
—
0
0
(3035350) Ketones [Presence] in Urine by Test strip
56
462
1.39
1.00
5.1
3.8
estimate
0.0
0.0
—
7
92
(3023103) Potassium [Moles/volume] in Serum or Plasma
104
959
1.60
0.99
22.9
16.8
mmol/l
4.0
4.0
0.22
104
931
(3023421) Hepatitis B virus surface Ab [Units/volume] in Serum
0
28
0.00
0.99
0.0
1.5
—
221.2
—
0
15
(1761482) Bacteria [#/volume] in Urine by Culture
0
30
0.00
0.99
0.0
4.2
—
—
—
0
0
(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells
6
27
2.28
0.95
1.5
1.7
—
—
—
0
0
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
6
27
2.28
0.95
1.3
1.7
—
—
—
0
0
(3003327) Ova and parasites identified in Stool by Light microscopy
6
27
2.28
0.95
1.2
1.2
—
—
—
0
0
(1001926) Buprenorphine [Presence] in Urine by Screen method
6
27
2.28
0.95
2.2
1.3
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
16
103
1.64
0.93
1.9
1.8
—
—
—
0
0
(3012544) pH of Venous blood
15
96
1.64
0.89
3.0
3.8
—
—
—
0
0
(3012336) Haptoglobin [Mass/volume] in Serum or Plasma
8
43
1.92
0.89
2.4
1.7
g/l
1.5
1.6
—
8
38
(40761511) CBC panel - Blood by Automated count
105
976
1.57
0.89
18.1
14.1
—
—
—
0
0
(3030366) Cystatin C [Mass/volume] in Serum or Plasma
6
30
2.05
0.88
1.7
2.9
mg/l
1.0
1.8
—
6
23
(3016879) Cocaine [Presence] in Urine
6
30
2.05
0.88
2.2
1.4
—
—
—
0
0
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
10
57
1.82
0.86
1.8
1.4
—
—
—
0
0
(3027008) Opiates [Presence] in Urine
6
31
1.98
0.85
2.2
1.4
—
—
—
0
0
(3000764) Benzodiazepines [Presence] in Urine
6
31
1.98
0.85
2.2
1.4
—
—
—
0
0
(3028300) Cannabinoids [Presence] in Urine
6
31
1.98
0.85
2.2
1.5
—
—
—
0
0
(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood
13
81
1.68
0.85
2.6
4.2
mmol/l
1.2
1.2
0.02
13
67
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
12
73
1.71
0.85
1.3
1.6
—
—
—
0
0
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
30
228
1.42
0.84
1.6
1.3
u/ml
9.1
0.8
0.45
11
57
(3020564) Creatinine [Moles/volume] in Serum or Plasma
106
991
1.56
0.83
23.3
16.6
umol/l
75.9
79.3
1.13
106
991
(3027944) Amphetamines [Presence] in Urine
6
32
1.92
0.83
2.2
1.4
—
—
—
0
0
(3023520) Reticulocytes [#/volume] in Blood
13
82
1.66
0.82
4.6
2.5
e9/l
82.2
65.7
0.83
13
64
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
18
124
1.53
0.81
1.4
1.5
—
—
—
0
0
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
6
34
1.80
0.77
1.8
1.9
—
—
—
0
0
(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection
5
23
2.22
0.77
1.6
1.4
—
—
—
0
0
(3029937) Albumin [Presence] in Urine by Test strip
32
251
1.37
0.75
7.4
4.1
estimate
0.0
0.0
—
8
87
(40768804) Tissue Pathology biopsy report
42
345
1.33
0.73
2.3
2.1
—
—
—
0
0
(3021601) Nitrite [Presence] in Urine by Test strip
54
460
1.31
0.73
5.9
5.2
estimate
0.0
0.0
—
8
90
(3052851) Hemolysis interference index of Serum or Plasma
5
25
2.04
0.73
3.4
3.1
—
—
—
0
0
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
17
119
1.50
0.71
14.1
8.3
—
—
—
0
0
(3010156) C reactive protein [Mass/volume] in Serum or Plasma by High sensitivity method
5
26
1.96
0.71
1.6
1.8
mg/l
0.9
3.0
—
5
20
(21494755) Public health laboratory ask at order entry panel
5
92
0.52
0.70
1.0
1.5
—
—
—
0
0
(3017143) Hepatitis C virus Ab [Presence] in Serum
16
111
1.51
0.70
1.4
1.5
—
—
—
0
0
(3022313) Gas panel - Capillary blood
7
42
1.71
0.69
5.1
4.5
—
—
—
0
0
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
5
27
1.89
0.69
1.2
1.2
—
—
—
0
0
(40768443) Skin Pathology biopsy report
5
27
1.89
0.69
1.2
1.2
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
37
303
1.32
0.65
4.4
2.9
—
—
—
0
0
(3009261) Glucose [Presence] in Urine by Test strip
54
466
1.29
0.65
5.3
3.8
estimate
0.0
0.0
—
9
83
(3021879) Hepatitis B virus core Ab [Presence] in Serum
10
63
1.64
0.64
1.5
1.5
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
15
105
1.49
0.63
1.9
1.7
—
—
—
0
0
(3002385) Erythrocyte distribution width [Ratio]
86
790
1.31
0.62
25.7
17.5
%
13.9
13.6
0.97
86
773
(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay
5
30
1.69
0.62
1.0
2.5
—
—
—
0
0
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
85
914
0.76
0.62
5.0
4.5
mmol/l
5.9
5.9
0.04
78
822
(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma
24
187
1.35
0.59
3.0
2.8
mmol/l
2.5
2.5
0.21
19
167
(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma
70
630
1.26
0.58
3.8
2.9
u/l
60.3
45.3
0.67
64
590
(3014111) Lactate [Moles/volume] in Serum or Plasma
13
90
1.50
0.58
6.6
4.8
mmol/l
1.2
1.3
0.14
13
85
(3027946) Carbon dioxide [Partial pressure] in Arterial blood
16
116
1.44
0.58
5.5
6.2
kpa
5.3
5.1
0.32
16
110
(3027801) Oxygen [Partial pressure] in Arterial blood
16
116
1.44
0.58
5.5
6.2
kpa
13.0
11.9
0.41
16
110
(3023024) Carbon dioxide [Partial pressure] in Capillary blood
9
63
1.46
0.54
4.1
4.3
kpa
5.0
5.1
—
9
57
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
93
871
1.29
0.52
18.4
13.6
ml/min/173m2
83.0
78.9
0.97
79
715
(3020891) Body temperature
6
40
1.53
0.52
5.3
3.9
—
—
—
0
0
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
87
926
0.78
0.52
5.7
5.1
mmol/l
2.7
2.7
0.31
81
843
(3012516) Albumin [Mass/volume] in Urine
32
269
1.26
0.46
2.8
2.9
mg/l
38.2
288.1
0.53
23
172
(3025941) Bacteria identified in Stool by Culture
8
56
1.46
0.43
1.5
1.2
—
—
—
0
0
(3016502) Oxygen saturation in Arterial blood
14
105
1.38
0.43
5.9
6.4
%
95.7
95.6
0.02
14
100
(3045414) Leukocytes [Presence] in Urine
5
33
1.54
0.42
1.4
2.1
—
—
—
0
0
(3035285) Chloride [Moles/volume] in Venous blood
0
15
0.00
0.41
0.0
2.8
—
107.3
—
0
15
(3041354) Potassium [Moles/volume] in Venous blood
0
15
0.00
0.41
0.0
2.8
—
4.1
—
0
15
(40768806) Pleura Pathology biopsy report
0
15
0.00
0.41
0.0
2.0
—
—
—
0
0
(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay
0
16
0.00
0.41
0.0
1.4
—
—
—
0
0
(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma
0
16
0.00
0.41
0.0
3.6
—
59.4
—
0
16
(3044889) 12 lead EKG panel
71
655
1.20
0.41
4.1
4.0
—
—
—
0
0
(3008401) Mugwort IgE Ab [Units/volume] in Serum
0
17
0.00
0.41
0.0
1.1
—
0.4
—
0
8
(3003888) Timothy IgE Ab [Units/volume] in Serum
0
17
0.00
0.41
0.0
1.1
—
4.0
—
0
10
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
42
369
1.21
0.41
6.0
3.9
—
—
—
0
0
(3026389) Candida sp identified in Specimen by Organism specific culture
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma
105
1009
1.31
0.39
13.3
9.9
u/l
25.7
25.5
0.05
105
970
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
5
80
0.61
0.36
1.0
1.5
—
—
—
0
0
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
6
46
1.32
0.33
3.3
2.6
%
2.1
1.0
—
6
46
(3017181) Myelocytes/100 leukocytes in Blood
11
84
1.34
0.31
2.7
3.4
%
1.7
1.0
—
6
28
(3002256) Pathology report gross observation
13
103
1.29
0.29
1.4
1.3
—
—
—
0
0
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
11
86
1.31
0.27
1.5
2.1
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
26
227
1.19
0.26
7.5
4.3
—
—
—
0
0
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
5
75
0.65
0.26
1.4
1.9
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
9
76
1.20
0.25
4.0
3.7
—
—
—
0
0
(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma
16
189
0.82
0.24
3.6
3.0
ug/l
0.8
0.9
0.24
11
113
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
29
258
1.16
0.24
5.1
4.3
%
20.4
22.3
0.26
16
112
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
84
874
0.87
0.23
4.3
4.1
mmol/l
1.3
1.3
0.17
77
793
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
87
902
0.87
0.22
4.8
4.6
mmol/l
4.5
4.6
0.32
81
831
(3049717) Cytology report of Urine Cyto stain
5
41
1.23
0.22
4.0
2.9
—
—
—
0
0
(3036428) Adenosine deaminase [Enzymatic activity/volume] in Pleural fluid
0
11
0.00
0.21
0.0
1.3
—
10.1
—
0
11
(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma
0
11
0.00
0.21
0.0
1.7
—
—
—
0
0
(3011648) Oxygen content in Venous blood
0
11
0.00
0.21
0.0
2.1
—
11.2
—
0
11
(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
(3011363) Streptococcus pneumoniae Ag [Presence] in Urine
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
(3042631) Mycobacterium sp identified in Specimen
0
10
0.00
0.21
0.0
5.6
—
—
—
0
0
(3053028) Streptococcus sp identified in Specimen by Organism specific culture
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
(4146454)
0
12
0.00
0.21
0.0
3.3
—
—
—
0
0
(40763082) Lactate dehydrogenase [Enzymatic activity/volume] in Pleural fluid by Lactate to pyruvate reaction
0
12
0.00
0.21
0.0
1.3
—
147.5
—
0
12
(3003740) Influenza virus B Ag [Presence] in Specimen
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
(3002523) Influenza virus A Ag [Presence] in Specimen
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay
0
13
0.00
0.21
0.0
4.5
—
137.3
—
0
13
(3033705) Calcium.ionized [Moles/volume] in Venous blood
0
14
0.00
0.20
0.0
2.9
—
—
—
0
0
(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
(3018387) Mycoplasma pneumoniae IgG Ab [Units/volume] in Serum
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
(3000492) Spirometry study
9
81
1.12
0.15
1.8
1.5
—
—
—
0
0
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
87
894
0.90
0.15
4.6
4.6
mmol/l
1.4
1.5
0.78
79
813
(3007461) Platelets [#/volume] in Blood
106
1041
1.15
0.13
32.3
20.7
e9/l
238.3
242.7
0.28
106
1013
(46235355) HIV 1 and 2 tests - Meaningful Use set
17
152
1.14
0.13
1.9
1.8
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
25
271
0.90
0.13
3.0
3.6
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
25
230
1.11
0.13
1.3
1.3
—
—
—
0
0
(3024731) MCV [Entitic volume]
106
1042
1.14
0.12
32.2
20.6
fl
90.6
90.9
0.23
106
1023
(3026361) Erythrocytes [#/volume] in Blood
106
1042
1.14
0.12
32.4
20.6
e12/l
4.4
4.5
1.32
106
1010
(3035941) MCH [Entitic mass]
106
1042
1.14
0.12
32.1
20.6
pg
30.1
30.3
0.29
106
1023
(3000963) Hemoglobin [Mass/volume] in Blood
106
1042
1.14
0.12
32.4
20.7
g/l
129.9
134.7
2.68
106
1022
(3010813) Leukocytes [#/volume] in Blood
106
1042
1.14
0.12
32.4
20.8
e9/l
6.8
6.5
0.62
106
1008
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
11
124
0.88
0.09
1.2
1.3
—
—
—
0
0
(3000330) Specific gravity of Urine by Test strip
5
48
1.04
0.09
1.4
3.9
—
—
—
0
0
(3020682) Albumin/Creatinine [Ratio] in Urine
30
283
1.08
0.09
3.3
3.7
mg/mmol
5.8
6.7
0.11
22
174
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
6
53
1.14
0.09
9.5
6.5
—
—
—
0
0
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
6
55
1.10
0.09
1.0
1.1
—
—
—
0
0
(3000067) Parathyrin.intact [Mass/volume] in Serum or Plasma
7
81
0.86
0.07
1.9
4.4
ng/l
63.3
87.2
—
7
69
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
85
863
0.95
0.05
6.3
5.7
mmol/mol
39.4
40.3
0.36
80
800
(3009542) Hematocrit [Volume Fraction] of Blood
86
853
1.03
0.01
24.2
14.3
%
38.7
40.1
0.86
57
613
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
58
587
0.98
0.01
3.0
3.0
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
15
146
1.03
0.00
2.5
1.5
—
—
—
0
0
(3035880) pH of Pleural fluid
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
(40762485) Glomerular basement membrane Ab [Units/volume] in Serum by Immunoassay
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
(40768441) Liver Pathology biopsy report
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3028369) Herpes simplex virus 1+2 DNA [Presence] in Specimen by NAA with probe detection
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3009306) Alpha-1-Fetoprotein [Mass/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
3.2
—
—
—
0
0
(3025018) Bordetella pertussis Ab [Titer] in Serum
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3020485) Acetaminophen [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3035933) Granulocytes/100 leukocytes in Blood
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3007847) Interleukin 2 Receptor Soluble [Units/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
2.0
—
1023.6
—
0
5
(3017446) Testosterone [Moles/volume] in Serum or Plasma
7
72
0.97
0.00
2.0
2.1
nmol/l
37.3
14.4
—
7
66
(3003245) Complement C1 esterase inhibitor [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.2
—
0.3
—
0
5
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
8
81
0.99
0.00
1.6
1.9
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
6
65
0.92
0.00
1.7
1.6
—
—
—
0
0
(3026470) Cobalt [Mass/volume] in Blood
0
5
0.00
0.00
0.0
2.0
—
1.6
—
0
5
(40766800) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells [Units/volume] corrected for background in Blood
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3019897) Erythrocyte distribution width [Ratio] by Automated count
0
5
0.00
0.00
0.0
3.0
—
13.9
—
0
5
(3012741) Chlamydophila pneumoniae IgA Ab [Titer] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3012447) Hantavirus puumala IgG Ab [Titer] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3036071) Salmonella sp Ab [Titer] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum
0
7
0.00
0.00
0.0
2.3
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
11
110
1.00
0.00
1.0
1.4
—
—
—
0
0
(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(3016436) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
5.7
—
241.2
—
0
6
(3047352) Trisomy 18 risk [Likelihood] in Fetus
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3051651) Icteric interference index of Serum or Plasma
0
5
0.00
0.00
0.0
3.2
—
—
—
0
0
(3011544) Albumin [Mass/volume] in Pleural fluid
0
5
0.00
0.00
0.0
1.0
—
18.6
—
0
5
(36306090) Helicobacter pylori [Presence] in Tissue by Organism specific culture
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
(3005033) Fetal Nuchal fold Thickness US
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(3043238) Trisomy 21 risk [Likelihood] in Fetus
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
(3019060) Gas panel - Arterial blood
7
71
0.99
0.00
3.0
4.1
—
—
—
0
0
(44816844) Macroprolactin [Units/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.9
—
—
—
0
0
(3022145) Colonoscopy Study observation
11
110
1.00
0.00
1.8
1.3
—
—
—
0
0
(40764127) Haemophilus influenzae DNA [Presence] in Specimen by NAA with probe detection
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
(3027529) Toxoplasma gondii IgM Ab [Units/volume] in Serum
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint G6_IDIOAUT and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_IDIOAUT | 2.777 [2.01, 3.83] | < 0.001 |
| Birth year | 0.994 [0.98, 1.01] | 0.307 |
During the follow-up period (1.1.1998 — 31.12.2019), 116 out of 349 females with G6_IDIOAUT died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_IDIOAUT | 1.888 [1.43, 2.49] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.003 |
During the follow-up period (1.1.1998 — 31.12.2019), 150 out of 429 males with G6_IDIOAUT died.
Mortality risk
Mortality risk for people of age
years, who have G6_IDIOAUT.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.284% | 0.399% |
| 5 | 1.651% | 2.298% |
| 10 | 4.088% | 5.4% |
| 15 | 7.869% | 10.144% |
| 20 | 13.603% | 17.063% |
Relationships between endpoints
↥Index endpoint: G6_IDIOAUT – Idiopathic peripheral autonomic neuropathy
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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