No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1004 |
4. Check minimum number of eventsNone |
1004 |
5. Include endpointsNone |
1004 |
6. Filter based on genotype QC (FinnGen only) |
1004 |
Control definitions (FinnGen only)
- Control exclude
- G6_NEUINFL
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Other encephalitis
based on the number of shared cases.
Similar with more cases:
- Encephalitis
- Inflammatory diseases of the central nervous system
- Neurological diseases
- Neurological diseases, wide definition
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 8321 | 4179 | 4069 |
| Only index persons | 7092 | 3622 | 3470 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.12 | 0.12 | 0.11 |
| Only index persons | 0.13 | 0.13 | 0.13 |
| Median age at first event (years) | |||
| Whole population | 44.69 | 46.74 | 42.37 |
| Only index persons | 42.17 | 44.29 | 39.97 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1004 | 555 | 449 |
| Unadjusted period prevalence (%) | 0.19 | 0.19 | 0.20 |
| Median age at first event (years) | 48.41 | 44.27 | 53.52 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 892
- Matched controls
- 8918
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G04.9
ICD-10 Finland
Encephalitis, myelitis and encephalomyelitis, unspecified
6853.6
323.0
406
*
TAB00
NOMESCO Finland
Lumbar puncture
18.9
153.9
247
177
G05.1*B00.4
ICD-10 Finland
Herpesviral meningoencephalitis
+∞
110.8
104
*
32309
ICD-8 Finland
Encephalitis, myelitis and encephalomyelitis, Unspecified
+∞
105.3
99
*
A86
ICD-10 Finland
Unspecified viral encephalitis
297.0
105.3
105
*
G04.8
ICD-10 Finland
Other encephalitis, myelitis and encephalomyelitis
+∞
90.1
85
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
7.7
87.5
225
376
AA1AD
NOMESCO Finland
CT of head and brain
4.2
70.2
337
1128
XA800
NOMESCO Finland
Neuropsychological investigation
10.0
64.4
135
156
G40.9
ICD-10 Finland
Epilepsy, unspecified
13.6
62.3
111
92
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
8.3
60.6
142
198
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
13.4
59.1
106
89
N03AX14
ATC
levetiracetam; systemic
14.9
54.6
93
69
5AB01
NOMESCO Finland
NA
504.1
48.8
48
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
4.0
45.6
212
651
G05.1
ICD-10 Finland
Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere
+∞
45.2
43
*
G05.8*M32.1
ICD-10 Finland
Encephalitis in systemic lupus erythematosus
+∞
44.1
42
*
G05.1*J09
ICD-10 Finland
Encephalitis, myelitis and encephalomyelitis in influenza caused by certain identified influenza viruses
+∞
43.1
41
*
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
12.7
40.3
73
62
ZX120
NOMESCO Finland
Intravenous
4.6
39.5
148
366
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
4.5
37.2
144
367
N03AF02
ATC
oxcarbazepine; oral
8.1
36.7
85
114
R56.8
ICD-10 Finland
Other and unspecified convulsions
5.7
35.8
108
209
G05.1*B01.1
ICD-10 Finland
Varicella encephalitis
+∞
34.6
33
*
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
19.5
33.0
50
27
A87.9
ICD-10 Finland
Viral meningitis, unspecified
26.2
32.6
45
18
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.2
32.0
191
697
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
10.2
31.8
64
67
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.3
30.8
412
2397
G05.1*B02.0
ICD-10 Finland
Zoster encephalitis
+∞
30.4
29
*
G03.9
ICD-10 Finland
Meningitis, unspecified
+∞
30.4
29
*
B00.4
ICD-10 Finland
Herpesviral encephalitis
+∞
30.4
29
*
R4120
NOMESCO Finland
Occupational therapy
4.6
29.8
109
260
TPH04
NOMESCO Finland
Cathetrisation of vein
2.8
29.8
235
1021
R50.9
ICD-10 Finland
Fever, unspecified
3.1
29.3
184
690
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
13.6
27.7
48
37
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
10.4
27.3
54
55
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
22.6
27.1
39
18
XF400
NOMESCO Finland
ECG with 12 standard connections
2.9
26.6
184
733
N03AG01
ATC
valproic acid; systemic, rectal
4.6
26.4
97
232
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.8
26.4
121
356
3238B
ICD-9 Finland
Encephalitis, myelitis and encephalomyelitis, Other causes of encephalitis[ENCEPHALITIS (MYELITIS,ENCEPHALOMYELITIS) VIROSA]
+∞
26.2
25
*
A28
ICPC
Limited function/disability NOS
3.0
25.7
162
606
R4110
NOMESCO Finland
Physiotherapy
2.4
25.5
271
1375
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
16.0
24.8
40
26
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.4
23.9
124
402
M32.1
ICD-10 Finland
Systemic lupus erythematosus with organ or system involvement
48.1
23.4
28
6
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.7
23.2
177
743
R4150
NOMESCO Finland
Neuropsychological rehabilitation
19.1
23.2
35
19
N03AX12
ATC
gabapentin; oral
2.7
22.9
175
734
WX892
NOMESCO Finland
Monitored bed care
3.8
22.0
97
275
R20.2
ICD-10 Finland
Paraesthesia of skin
4.1
21.5
88
233
R41.0
ICD-10 Finland
Disorientation, unspecified
7.1
21.4
53
79
G35
ICD-10 Finland
Multiple sclerosis
7.7
20.9
49
67
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.3
20.7
223
1121
N03AX16
ATC
pregabalin; oral
2.3
20.5
236
1223
2AB04
NOMESCO Finland
NA
49.2
20.2
24
5
N03AX18
ATC
lacosamide; systemic
17.8
20.1
31
18
M32.0
ICD-10 Finland
Drug-induced systemic lupus erythematosus
58.9
20.0
23
*
G05.1*J10.8
ICD-10 Finland
Encephalitis, myelitis and encephalomyelitis in influenza caused by other identified influenza virus
+∞
19.9
19
*
B94.1
ICD-10 Finland
Sequelae of viral encephalitis
+∞
19.9
19
*
R51.80
ICD-10 Finland
Headache
2.5
19.8
169
751
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.1
19.2
277
1580
183
Kela drug reimbursment
Lamotrigin and topiramate
14.4
19.2
32
23
6BA02
NOMESCO Finland
NA
35.2
19.0
24
7
N03AB02
ATC
phenytoin; systemic
13.2
18.5
32
25
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
3.1
18.4
106
369
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.7
18.2
138
572
TKC20
NOMESCO Finland
Catheterisation of bladder
3.6
18.1
86
259
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.9
17.8
75
204
N05BA09
ATC
clobazam; oral
16.0
17.6
28
18
G37.9
ICD-10 Finland
Demyelinating disease of central nervous system, unspecified
12.9
17.2
30
24
G05.1*A85.0
ICD-10 Finland
Encephalitis, myelitis or encephalomyelitis (in) enteroviral
+∞
16.7
16
*
R33
ICD-10 Finland
Retention of urine
3.3
16.5
87
284
XA400
NOMESCO Finland
EEG
18.3
16.5
25
14
H02AB06
ATC
prednisolone; systemic
1.8
16.5
412
2846
N99
ICPC
Neurological disease other
9.7
16.0
32
34
J01MA12
ATC
levofloxacin; systemic
2.3
16.0
167
818
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
6.1
15.7
43
74
H02AB07
ATC
prednisone; oral
2.4
15.6
144
662
F05.9
ICD-10 Finland
Delirium, unspecified
6.9
15.4
38
57
WW400
NOMESCO Finland
Plasmaferesis
45.8
15.1
18
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.4
15.1
142
658
NA7BG
NOMESCO Finland
Spine and spinal cord MRI examination with high intensity magnet
16.8
14.8
23
14
N71
ICPC
Meningitis/encephalitis
+∞
14.6
14
*
L28
ICPC
Limited function/disability (L)
2.3
14.6
146
697
L04AX01
ATC
azathioprine; systemic
3.8
14.3
60
164
C03CA01
ATC
furosemide; systemic
2.0
14.2
223
1291
M05BA04
ATC
alendronic acid; oral
2.9
14.2
90
333
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
3.5
14.2
67
202
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.8
13.9
90
338
L04AA06
ATC
mycophenolic acid; systemic
6.4
13.9
36
58
G40.21
ICD-10 Finland
Partial epileptic seizure with cloudiness and automatism
24.2
13.8
19
8
R4130
NOMESCO Finland
Speech therapy
6.3
13.8
36
59
7100A
ICD-9 Finland
Diffuse diseases of connective tissue, Systemic lupus erythematosus
76.3
13.6
15
*
32308
ICD-8 Finland
Encephalitis, myelitis and encephalomyelitis, Alia definita
+∞
13.6
13
*
G04.0
ICD-10 Finland
Acute disseminated encephalitis
+∞
13.6
13
*
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
3.1
13.4
75
253
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.9
13.4
82
298
NA2CG
NOMESCO Finland
Thoracal spine extensive MRI examination with high intensity magnet
12.4
13.1
23
19
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
5.9
13.1
36
63
G37.3
ICD-10 Finland
Acute transverse myelitis in demyelinating disease of central nervous system
50.8
12.9
15
*
N08.5*M32.1
ICD-10 Finland
Glomerular disorders in systemic lupus erythematosus
50.8
12.9
15
*
J01DB01
ATC
cefalexin; oral
1.8
12.8
709
6050
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
5.5
12.8
37
69
R42
ICD-10 Finland
Dizziness and giddiness
2.0
12.8
189
1065
109
Kela drug reimbursment
Multiple sclerosis
7.2
12.7
30
43
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
5.2
12.4
38
76
J05AB11
ATC
valaciclovir; oral
2.3
12.2
124
595
R11
ICD-10 Finland
Nausea and vomiting
2.7
12.1
86
341
N05BA01
ATC
diazepam; systemic, rectal
2.2
11.9
125
610
H02AB09
ATC
hydrocortisone; systemic
4.3
11.9
43
103
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.0
11.8
70
249
N03AF01
ATC
carbamazepine; oral, rectal
3.3
11.8
60
192
N03AX09
ATC
lamotrigine; oral
3.3
11.6
58
184
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.0
11.6
160
876
JN4BD
NOMESCO Finland
Extensive body CT
2.4
11.5
98
431
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.0
11.5
149
795
G41.9
ICD-10 Finland
Status epilepticus, unspecified
13.8
11.5
19
14
G73.7*M32.1
ICD-10 Finland
Myopathy in systemic lupus erythematosus
+∞
11.5
11
*
G02.0*B00.3
ICD-10 Finland
Herpesviral meningitis
+∞
11.5
11
*
5CM18
NOMESCO Finland
NA
35.5
11.3
14
*
M32.8
ICD-10 Finland
Other forms of systemic lupus erythematosus
25.4
11.2
15
6
N28
ICPC
Limited function/disability (N)
8.4
10.8
23
28
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
2.6
10.8
78
313
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
2.5
10.7
84
353
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.5
10.6
83
347
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
7.1
10.6
25
36
N05CF01
ATC
zopiclone; oral
1.7
10.6
257
1698
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
8.6
10.6
22
26
A02BC02
ATC
pantoprazole; systemic
1.6
10.5
521
4168
G09
ICD-10 Finland
Sequelae of inflammatory diseases of central nervous system
+∞
10.4
10
*
R53
ICD-10 Finland
Malaise and fatigue
1.9
10.4
174
1017
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
6.5
10.4
26
41
G40.89
ICD-10 Finland
Other epilepsy
16.3
10.4
16
10
73410
ICD-8 Finland
Diffuse diseases of connective tissue, Systemic lupus erythematosus
32.9
10.3
13
*
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
2.9
10.3
63
228
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
6.7
10.2
25
38
J01AA02
ATC
doxycycline; systemic
1.6
10.2
639
5408
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.7
10.0
42
116
D64.9
ICD-10 Finland
Anaemia, unspecified
2.4
9.9
87
387
G61.0
ICD-10 Finland
Guillain-Barré syndrome
20.3
9.8
14
7
N05AH04
ATC
quetiapine; oral
1.9
9.8
152
866
WX730
NOMESCO Finland
Conventional respirator
6.2
9.7
25
41
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
5.4
9.7
28
53
G97.0
ICD-10 Finland
Cerebrospinal fluid leak from spinal puncture
6.5
9.6
24
38
N03AX11
ATC
topiramate; oral
4.3
9.6
34
81
G01*A69.2
ICD-10 Finland
Meningitis (in) Lyme disease
+∞
9.4
9
*
WX704
NOMESCO Finland
Intubation
2.5
9.1
71
297
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
7.1
9.1
21
30
F05.8
ICD-10 Finland
Other delirium
15.8
9.0
14
9
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
4.0
8.9
34
87
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.0
8.9
114
604
J01MA02
ATC
ciprofloxacin; systemic
1.6
8.9
300
2152
157
Kela drug reimbursment
Dimethyl fumarate, glatiramer acetate, interferon beta and teriflunomid (Multiple sclerosis)
6.4
8.8
22
35
RS221
NOMESCO Finland
NA
5.4
8.8
25
47
SPAT1254
SPAT
Administration of medicine
1.9
8.8
132
743
A41.9
ICD-10 Finland
Sepsis, unspecified
3.6
8.6
37
105
A02BC01
ATC
omeprazole; systemic
1.7
8.6
212
1396
A69.2
ICD-10 Finland
Lyme disease
3.1
8.5
46
156
R90.8
ICD-10 Finland
Other abnormal findings on diagnostic imaging of central nervous system
8.0
8.4
18
23
TPH07
NOMESCO Finland
Cathetrisation of artery
2.2
8.4
85
408
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
5.3
8.3
24
46
G05.1*J11.8
ICD-10 Finland
Encephalitis, myelitis or encephalomyelitis in suspected influenza
+∞
8.3
8
*
N02AA05
ATC
oxycodone; systemic
2.0
8.3
112
605
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
3.9
8.3
33
88
N06AX11
ATC
mirtazapine; oral
1.6
8.3
258
1806
J96.0
ICD-10 Finland
Acute respiratory failure
6.6
8.2
20
31
XF600
NOMESCO Finland
Bloodpressure measurement
2.5
8.1
60
246
G41.0
ICD-10 Finland
Grand mal status epilepticus
33.7
8.1
10
*
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
8.1
221
1496
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.0
8.0
108
583
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.8
8.0
32
86
SPAT1216
SPAT
Assessment of functional ability
1.9
8.0
120
673
N02BE01
ATC
paracetamol; systemic, rectal
1.6
8.0
707
6278
B01AC04
ATC
clopidogrel; oral
2.0
7.9
109
594
H53.2
ICD-10 Finland
Diplopia
3.5
7.9
35
103
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.5
7.9
422
3345
303
Kela drug reimbursment
Dimethyl fumarate, interferon beta, glatiramer acetate and teriflunomid (Multiple sclerosis)
5.5
7.9
22
41
A06AD11
ATC
lactulose; oral
1.9
7.8
111
610
B02.8
ICD-10 Finland
Zoster with other complications
15.2
7.7
12
8
TKC10
NOMESCO Finland
Percutaneous puncture of bladder
7.5
7.7
17
23
D86.8
ICD-10 Finland
Sarcoidosis of other and combined sites
7.5
7.7
17
23
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
2.7
7.6
50
192
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
7.5
213
1447
M03BX01
ATC
baclofen; systemic
4.0
7.5
28
71
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.4
7.5
64
283
P01BA02
ATC
hydroxychloroquine; oral
2.2
7.5
77
373
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
7.4
172
1111
J01FF01
ATC
clindamycin; systemic
1.6
7.3
218
1503
XKD06
NOMESCO Finland
Physiologic investigation of micturition
3.4
7.3
34
104
R47.0
ICD-10 Finland
Dysphasia and aphasia
6.9
7.3
17
25
TDM10
NOMESCO Finland
Puncture of maxillary antrum
3.0
7.3
40
138
F07.1
ICD-10 Finland
Postencephalitic syndrome
+∞
7.3
7
*
B02.0
ICD-10 Finland
Zoster encephalitis
+∞
7.3
7
*
32099
ICD-8 Finland
Meningitis, With no organism specified as cause
+∞
7.3
7
*
J05AB01
ATC
aciclovir; systemic
1.7
7.3
166
1065
H53.1
ICD-10 Finland
Subjective visual disturbances
2.4
7.3
57
242
R1260
NOMESCO Finland
Evaluation of communicative skills
4.9
7.2
22
46
J06BA01
ATC
immunoglobulins, normal human, for extravascular adm.; systemic
30.3
7.2
9
*
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.1
7.1
83
423
D80.1
ICD-10 Finland
Nonfamilial hypogammaglobulinaemia
20.2
7.1
10
5
Z71.8
ICD-10 Finland
Other specified counselling
1.6
7.1
194
1307
A29
ICPC
General symptom/complaint other
2.0
7.1
87
453
N02AX02
ATC
tramadol; systemic, rectal
1.5
7.1
321
2438
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
2.1
7.1
76
375
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.9
7.1
98
534
L04AX07
ATC
dimethyl fumarate; oral
10.1
7.0
13
13
N06AA09
ATC
amitriptyline; systemic
2.1
7.0
80
404
G40.19
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
7.1
7.0
16
23
N03AE01
ATC
clonazepam; systemic
2.4
7.0
56
241
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
3.0
7.0
37
125
G81.9
ICD-10 Finland
Hemiplegia, unspecified
5.9
6.9
18
31
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.9
6.9
95
515
SPAT1255
SPAT
Intravenous administration of medicine
2.3
6.9
60
268
N30.0
ICD-10 Finland
Acute cystitis
1.9
6.9
106
602
A04
ICPC
Weakness/tiredness general
1.9
6.9
106
602
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.0
6.9
89
474
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
2.4
6.9
57
249
N05BA04
ATC
oxazepam; oral
1.6
6.8
195
1325
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
2.8
6.8
41
150
TAB22
NOMESCO Finland
Stoppin epidural fluid escape with coagulated blood
5.4
6.8
19
36
G40
ICD-10 Finland
Epilepsy
6.2
6.8
17
28
M32
ICD-10 Finland
Systemic lupus erythematosus
40.4
6.8
8
*
WX872
NOMESCO Finland
Intensive care
2.7
6.8
44
169
N03AX23
ATC
brivaracetam; systemic
16.8
6.8
10
6
XCD10
NOMESCO Finland
Electrophysiological examination of eye
3.8
6.7
26
69
B24
ICD-10 Finland
Unspecified human immunodeficiency virus [HIV] disease
22.7
6.7
9
*
G95.9
ICD-10 Finland
Disease of spinal cord, unspecified
22.7
6.7
9
*
ADB00
NOMESCO Finland
Implantation of vagus nerve stimulating device
22.7
6.7
9
*
N03AX22
ATC
perampanel; oral
22.7
6.7
9
*
N06AX16
ATC
venlafaxine; oral
1.8
6.6
109
630
N05CD08
ATC
midazolam; nasal, systemic
3.9
6.6
25
65
C07AB07
ATC
bisoprolol; oral
1.5
6.5
325
2506
WX110
NOMESCO Finland
Local anesthesy
1.4
6.5
567
4880
C01CA24
ATC
epinephrine; parenteral
2.3
6.4
58
266
NF1AA
NOMESCO Finland
Hip X-ray examination
2.1
6.4
67
327
J45.9
ICD-10 Finland
Asthma, unspecified
1.7
6.4
137
862
R55
ICD-10 Finland
Syncope and collapse
2.0
6.4
82
436
B01AB05
ATC
enoxaparin; parenteral
1.5
6.4
221
1573
UGC12
NOMESCO Finland
Flexible bronchoscopy
2.2
6.3
59
273
N29
ICPC
Neurological sympt/complt other
4.2
6.3
22
53
B02.1
ICD-10 Finland
Zoster meningitis
+∞
6.3
6
*
G00.9
ICD-10 Finland
Bacterial meningitis, unspecified
+∞
6.3
6
*
3238X
ICD-9 Finland
Encephalitis, myelitis and encephalomyelitis, Other causes of encephalitis[ENCEPHALITIS (MYELITIS, ENCEPHALOMYELITIS) ALIA DEF]
+∞
6.3
6
*
R51
ICD-10 Finland
Headache
2.4
6.3
48
203
L89
ICD-10 Finland
Decubitus ulcer and pressure area
4.8
6.2
19
40
M31.1
ICD-10 Finland
Thrombotic microangiopathy
26.9
6.2
8
*
UKC02
NOMESCO Finland
Cystoscopy
1.8
6.2
116
700
AA1BM
NOMESCO Finland
MRI examination of brain with 3 Tesla magnet
5.1
6.2
18
36
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
5.8
6.2
16
28
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
3.3
6.1
28
86
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
2.2
6.1
58
273
N06AX21
ATC
duloxetine; oral
1.9
6.1
87
482
G44.8
ICD-10 Finland
Other specified headache syndromes
6.1
6.0
15
25
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.6
6.0
40
157
Mortality – FinRegistry
↥Association
Association between endpoint G6_ENCEPHOTH and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_ENCEPHOTH | 2.45 [2.02, 2.98] | < 0.001 |
| Birth year | 0.991 [0.98, 1.0] | 0.037 |
During the follow-up period (1.1.1998 — 31.12.2019), 661 out of 2876 females with G6_ENCEPHOTH died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_ENCEPHOTH | 2.573 [2.12, 3.12] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.009 |
During the follow-up period (1.1.1998 — 31.12.2019), 676 out of 2598 males with G6_ENCEPHOTH died.
Mortality risk
Mortality risk for people of age
years, who have G6_ENCEPHOTH.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.27% | 0.56% |
| 5 | 1.504% | 3.404% |
| 10 | 3.471% | 7.97% |
| 15 | 6.499% | 14.497% |
| 20 | 10.676% | 23.104% |
Relationships between endpoints
↥Index endpoint: G6_ENCEPHOTH – Other encephalitis
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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