Cerebral cysts

G6_CERCYST

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 G93
  • Hospital discharge: ICD-9 3480
  • Cause of death: ICD-10 G93
  • Cause of death: ICD-9 3480

2 out of 7 registries used, show all original rules.

2240

4. Check minimum number of events

None

2240

5. Include endpoints

None

2240

6. Filter based on genotype QC (FinnGen only)

2240

Control definitions (FinnGen only)

Control exclude
G6_OTHNEU

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
G90-G99
Name in latin
Aliae morbositates cerebri

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 20739 9226 11265
Only index persons 15721 7529 8192
Unadjusted period prevalence (%)
Whole population 0.29 0.26 0.31
Only index persons 0.30 0.28 0.31
Median age at first event (years)
Whole population 52.04 47.69 55.28
Only index persons 49.56 44.95 53.80

-FinnGen-

Key figures

All Female Male
Number of individuals 2240 1249 991
Unadjusted period prevalence (%) 0.43 0.43 0.44
Median age at first event (years) 49.33 41.94 58.65

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2036
Matched controls
20361
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G93.0
ICD-10 Finland
Cerebral cysts
7074.3
323.0
539
*
G93.1
ICD-10 Finland
Anoxic brain damage, not elsewhere classified
+∞
323.0
436
*
G93.2
ICD-10 Finland
Benign intracranial hypertension
+∞
323.0
318
*
G93.4
ICD-10 Finland
Encephalopathy, unspecified
+∞
299.6
280
*
G93.3
ICD-10 Finland
Postviral fatigue syndrome
329.2
259.5
258
9
I46.0
ICD-10 Finland
Cardiac arrest with successful resuscitation
33.7
202.7
268
91
S01EC01
ATC
acetazolamide; systemic
17.6
149.1
241
154
H47.1
ICD-10 Finland
Papilloedema, unspecified
84.4
145.8
163
21
AA1AD
NOMESCO Finland
CT of head and brain
4.1
137.9
661
2137
TAB00
NOMESCO Finland
Lumbar puncture
10.7
132.3
269
286
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
6.0
120.1
365
716
R51.80
ICD-10 Finland
Headache
3.9
105.7
515
1632
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
5.3
96.5
325
709
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
4.7
78.5
294
710
G93.99
ICD-10 Finland
Disorder of brain, unspecified
+∞
69.1
66
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.0
67.4
449
1734
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.2
65.4
399
1445
G97.0
ICD-10 Finland
Cerebrospinal fluid leak from spinal puncture
658.6
65.3
64
*
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
30.2
64.7
87
30
G93.8
ICD-10 Finland
Other specified disorders of brain
+∞
63.9
61
*
G93.6
ICD-10 Finland
Cerebral oedema
+∞
61.8
59
*
XA800
NOMESCO Finland
Neuropsychological investigation
5.9
59.7
175
317
R53
ICD-10 Finland
Malaise and fatigue
2.6
56.5
512
2359
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
7.0
53.7
138
209
I49.0
ICD-10 Finland
Ventricular fibrillation and flutter
18.5
51.4
80
45
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
4.5
51.2
195
471
N03AX14
ATC
levetiracetam; systemic
7.2
48.2
121
177
N06AX16
ATC
venlafaxine; oral
2.7
44.8
357
1506
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.7
44.1
209
614
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
117.6
42.9
46
*
XCK00
NOMESCO Finland
Perimetry
3.9
42.8
189
523
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.9
42.7
287
1088
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.9
42.6
188
519
G93.90
ICD-10 Finland
Brain death
+∞
41.8
40
*
N03AX11
ATC
topiramate; oral
5.9
39.8
116
208
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
3.3
38.8
207
666
G91.9
ICD-10 Finland
Hydrocephalus, unspecified
+∞
38.7
37
*
R56.8
ICD-10 Finland
Other and unspecified convulsions
4.0
38.6
165
443
N03AX16
ATC
pregabalin; oral
2.2
38.5
467
2425
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
6.9
37.9
97
146
Z01.8
ICD-10 Finland
Other specified special examinations
2.2
37.4
463
2421
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.6
37.1
297
1245
3480A
ICD-9 Finland
Other conditions of brain, Cerebral cysts
+∞
36.6
35
*
N03AX12
ATC
gabapentin; oral
2.5
36.5
329
1469
N03AF02
ATC
oxcarbazepine; oral
5.0
36.5
121
252
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
8.2
36.4
83
105
TAB22
NOMESCO Finland
Stoppin epidural fluid escape with coagulated blood
15.0
35.9
60
41
WX730
NOMESCO Finland
Conventional respirator
7.8
35.7
84
112
G93.5
ICD-10 Finland
Compression of brain
+∞
35.5
34
*
R42
ICD-10 Finland
Dizziness and giddiness
2.2
35.2
421
2161
N03AG01
ATC
valproic acid; systemic, rectal
3.3
35.1
191
623
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.0
34.2
553
3216
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
7.0
33.6
85
126
N05AH04
ATC
quetiapine; oral
2.2
33.5
395
2008
G40.9
ICD-10 Finland
Epilepsy, unspecified
4.8
33.2
114
247
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
11.6
33.1
62
55
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
3.5
32.1
161
493
G44.2
ICD-10 Finland
Tension-type headache
2.4
31.8
303
1389
C03CA01
ATC
furosemide; systemic
2.0
31.8
497
2839
G45.1
ICD-10 Finland
Carotid artery syndrome (hemispheric)
+∞
31.3
30
*
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.3
30.9
305
1422
AAF20
NOMESCO Finland
Revision of shunt of ventricle of brain
162.5
30.7
32
*
G91.1
ICD-10 Finland
Obstructive hydrocephalus
+∞
30.3
29
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.8
29.6
773
5252
R41.0
ICD-10 Finland
Disorientation, unspecified
5.7
28.7
84
152
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
6.1
28.6
79
133
N05BA04
ATC
oxazepam; oral
1.9
28.4
493
2913
Z2445
NOMESCO Finland
Psychologist
3.6
28.3
134
392
C07AB07
ATC
bisoprolol; oral
1.7
28.1
795
5508
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
4.8
28.0
96
208
N06AB04
ATC
citalopram; systemic
2.0
27.8
444
2538
N06AX11
ATC
mirtazapine; oral
1.8
27.8
617
3958
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
5.8
27.3
79
141
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
3.0
27.3
170
605
N05CF01
ATC
zopiclone; oral
1.8
27.0
584
3707
N06AX21
ATC
duloxetine; oral
2.5
26.4
227
981
WX872
NOMESCO Finland
Intensive care
3.5
26.3
129
388
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
4.0
26.2
110
290
N03AX09
ATC
lamotrigine; oral
3.2
25.9
142
465
G91.0
ICD-10 Finland
Communicating hydrocephalus
263.8
25.7
26
*
AAF99
NOMESCO Finland
Other shunt operation on ventricle of brain or intracerebral cyst
136.7
25.7
27
*
CS494
NOMESCO Finland
Other visual field testing
5.9
25.5
72
125
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.1
25.2
318
1647
TPH04
NOMESCO Finland
Cathetrisation of vein
1.9
25.0
400
2280
F48.0
ICD-10 Finland
Neurasthenia
26.6
24.9
34
13
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.7
24.7
179
701
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.1
24.6
306
1574
L28
ICPC
Limited function/disability (L)
2.2
24.5
278
1373
N03AE01
ATC
clonazepam; systemic
3.1
24.4
138
461
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.5
24.2
200
846
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
3.2
24.1
134
443
WX930
NOMESCO Finland
Thepapeutic hypothermia
29.5
24.1
32
11
G91.2
ICD-10 Finland
Normal-pressure hydrocephalus
+∞
24.0
23
*
R50.9
ICD-10 Finland
Fever, unspecified
2.1
24.0
306
1592
R06.0
ICD-10 Finland
Dyspnoea
1.8
23.8
448
2698
A07AA11
ATC
rifaximin; oral
27.1
23.6
32
12
A06AD11
ATC
lactulose; oral
2.2
23.4
271
1351
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.6
23.1
173
690
C07AA05
ATC
propranolol; systemic
1.9
22.7
399
2341
K70.3
ICD-10 Finland
Alcoholic cirrhosis of liver
7.2
22.6
55
78
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
2.6
22.6
168
670
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
2.6
22.5
171
689
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
7.1
22.4
55
79
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
5.8
22.4
64
113
R55
ICD-10 Finland
Syncope and collapse
2.4
22.2
209
943
K74.6
ICD-10 Finland
Other and unspecified cirrhosis of liver
8.4
21.9
48
58
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.1
21.8
280
1457
C03DA01
ATC
spironolactone; oral
2.4
21.7
203
914
G45.0
ICD-10 Finland
Vertebro-basilar artery syndrome
116.3
21.6
23
*
N05BA01
ATC
diazepam; systemic, rectal
2.1
21.6
272
1401
A28
ICPC
Limited function/disability NOS
2.2
21.3
245
1214
H53.1
ICD-10 Finland
Subjective visual disturbances
3.0
21.3
126
433
N29
ICPC
Neurological sympt/complt other
6.0
20.9
58
99
YKA02
NOMESCO Finland
Excision of kidneys from cadaver donor
+∞
20.9
20
*
A02BC02
ATC
pantoprazole; systemic
1.6
20.8
1145
9194
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.2
20.4
217
1039
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.9
20.0
303
1680
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
2.9
20.0
122
431
G43.9
ICD-10 Finland
Migraine, unspecified
2.6
19.9
149
597
SPAT1301
SPAT
No procedures
1.6
19.8
597
4113
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
2.7
19.6
143
562
M03BX01
ATC
baclofen; systemic
6.3
19.6
52
84
AAF00
NOMESCO Finland
Ventriculostomy
21.8
19.5
28
13
R68.88
ICD-10 Finland
Other specified general symptoms and signs, not elsewhere classified.
11.4
19.5
36
32
H53.4
ICD-10 Finland
Visual field defects
5.3
19.4
60
117
N03AX18
ATC
lacosamide; systemic
10.7
19.4
37
35
R4150
NOMESCO Finland
Neuropsychological rehabilitation
9.2
19.4
40
44
N05AX08
ATC
risperidone; systemic
2.4
19.2
168
728
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.2
19.2
101
322
G91.8
ICD-10 Finland
Other hydrocephalus
+∞
18.8
18
*
AAF40
NOMESCO Finland
Shunt of cyst of brain to peritoneum
+∞
18.8
18
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.7
18.8
421
2659
N06AB10
ATC
escitalopram; oral
1.8
18.7
407
2543
GBB00
NOMESCO Finland
Tracheostomy
7.0
18.7
46
67
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.8
18.6
121
442
AAF25
NOMESCO Finland
Removal of shunt of ventricle of brain
191.7
18.6
19
*
R11
ICD-10 Finland
Nausea and vomiting
2.4
18.5
164
719
N02AX02
ATC
tramadol; systemic, rectal
1.6
18.5
725
5320
N03AF01
ATC
carbamazepine; oral, rectal
2.9
18.5
114
406
TPH07
NOMESCO Finland
Cathetrisation of artery
2.2
18.3
188
884
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.2
18.3
197
946
Z2446
NOMESCO Finland
Social worker
2.4
18.2
157
678
G41.9
ICD-10 Finland
Status epilepticus, unspecified
11.1
18.2
34
31
H02AB06
ATC
prednisolone; systemic
1.5
18.0
830
6314
R90.8
ICD-10 Finland
Other abnormal findings on diagnostic imaging of central nervous system
7.7
17.9
41
54
N28
ICPC
Limited function/disability (N)
6.8
17.6
44
66
H53.2
ICD-10 Finland
Diplopia
4.1
17.5
68
169
K90
ICPC
Stroke/cerebrovascular accident
4.5
17.1
60
135
WX704
NOMESCO Finland
Intubation
2.4
16.9
148
642
G43.3
ICD-10 Finland
Complicated migraine
4.6
16.7
58
129
FPG30
NOMESCO Finland
Implantation of cardioverter-defibrillator with ventricular electrode
11.2
16.7
31
28
G95.0
ICD-10 Finland
Syringomyelia and syringobulbia
+∞
16.7
16
*
N06AX12
ATC
bupropion; oral
2.3
16.5
151
671
Q79.6
ICD-10 Finland
Ehlers-Danlos syndrome
13.5
16.5
28
21
N05BA09
ATC
clobazam; oral
9.6
16.4
33
35
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.8
16.3
105
384
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
5.0
16.3
52
106
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
16.2
662
4868
ZXD05
NOMESCO Finland
Urgent procedure
1.6
16.1
593
4253
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
4.6
16.1
55
121
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.7
16.0
339
2094
183
Kela drug reimbursment
Lamotrigin and topiramate
6.3
15.9
42
68
AA1AA
NOMESCO Finland
Head X-ray examination
12.3
15.8
28
23
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
5.2
15.8
49
97
G45.3
ICD-10 Finland
Amaurosis fugax
33.6
15.7
20
6
N18
ICPC
Paralysis/weakness
5.8
15.7
44
77
R4120
NOMESCO Finland
Occupational therapy
2.5
15.7
124
512
R51
ICD-10 Finland
Headache
2.5
15.6
122
500
A03FA01
ATC
metoclopramide; systemic, rectal
1.7
15.6
354
2231
H47.3
ICD-10 Finland
Other disorders of optic disc
22.2
15.5
22
10
M35.7
ICD-10 Finland
Hypermobility syndrome
5.0
15.5
49
99
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.1
15.5
187
945
N06AB06
ATC
sertraline; oral
1.9
15.4
228
1244
A04
ICPC
Weakness/tiredness general
1.9
15.4
254
1444
C09AA05
ATC
ramipril; oral
1.7
15.3
365
2333
I85.9
ICD-10 Finland
Oesophageal varices without bleeding
7.6
15.2
35
47
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
7.6
15.2
35
47
N05AH03
ATC
olanzapine; systemic
2.3
15.1
137
609
R07.4
ICD-10 Finland
Chest pain, unspecified
1.6
14.8
417
2786
WX882
NOMESCO Finland
High dependency care
3.3
14.8
74
229
A02BC05
ATC
esomeprazole; systemic
1.5
14.7
675
5065
AAF10
NOMESCO Finland
Lumboperitoneal shunt
+∞
14.6
14
*
G97.1
ICD-10 Finland
Other reaction to spinal and lumbar puncture
+∞
14.6
14
*
A41.9
ICD-10 Finland
Sepsis, unspecified
3.2
14.6
76
242
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
3.8
14.6
61
163
SPAT1229
SPAT
Assessment of need for aid
2.3
14.6
136
612
E66.8
ICD-10 Finland
Other obesity
2.6
14.5
110
445
R1250
NOMESCO Finland
Evaluation of functional capability
4.2
14.5
54
130
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
3.1
14.4
79
261
H02AB09
ATC
hydrocortisone; systemic
3.5
14.4
66
191
G44.8
ICD-10 Finland
Other specified headache syndromes
5.8
14.4
40
70
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.2
14.3
142
658
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.8
14.3
250
1449
K72.1
ICD-10 Finland
Chronic hepatic failure
42.8
14.1
17
*
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.1
14.0
163
809
G47.3
ICD-10 Finland
Sleep apnoea
1.7
13.9
344
2215
N01
ICPC
Headache
1.9
13.8
230
1308
XF404
NOMESCO Finland
Ambulatory ECG
2.1
13.6
160
799
WX892
NOMESCO Finland
Monitored bed care
2.2
13.6
140
661
AAF15
NOMESCO Finland
Ventriculoatrial shunt
75.6
13.6
15
*
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
2.0
13.6
187
995
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
2.1
13.6
164
827
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
2.6
13.5
100
399
SPAT1255
SPAT
Intravenous administration of medicine
2.3
13.5
123
546
E66.01
ICD-10 Finland
Obesity due to excess calories
2.1
13.5
163
822
N99
ICPC
Neurological disease other
6.8
13.4
33
49
F33.11
ICD-10 Finland
Recurrent depression, moderate episode of somatic syndrome
3.5
13.4
62
181
K70.4
ICD-10 Finland
Alcoholic hepatic failure
11.5
13.3
24
21
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.5
13.3
462
3245
N04BC09
ATC
rotigotine; transdermal
10.5
13.2
25
24
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
5.5
13.1
38
70
A98
ICPC
Health maint/preventive medicine
0.6
13.1
1673
17952
I47.2
ICD-10 Finland
Ventricular tachycardia
3.9
13.1
53
138
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
2.6
13.1
98
394
G41.0
ICD-10 Finland
Grand mal status epilepticus
28.5
13.0
17
6
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.7
12.9
273
1677
B03BA03
ATC
hydroxocobalamin; parenteral
2.5
12.9
102
420
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
2.9
12.9
77
270
H03AA01
ATC
levothyroxine sodium; systemic
1.6
12.9
385
2599
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.4
12.8
113
495
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
2.4
12.8
107
456
S06.0
ICD-10 Finland
Concussion
1.9
12.7
192
1056
C07AB02
ATC
metoprolol; systemic
1.7
12.7
313
2007
YJA10
NOMESCO Finland
Excision of liver from cadaver donor
+∞
12.5
12
*
M79.7
ICD-10 Finland
Fibromyalgia
3.1
12.5
68
225
R4110
NOMESCO Finland
Physiotherapy
1.5
12.5
434
3042
ZX120
NOMESCO Finland
Intravenous
2.0
12.5
172
914
G41.2
ICD-10 Finland
Complex partial status epilepticus
20.2
12.5
18
9
TK800
NOMESCO Finland
Hemodialysis
3.9
12.4
50
130
AA7AA
NOMESCO Finland
Liquor cerebri shunt X-ray examinatin without contrast
130.8
12.4
13
*
Q04.6
ICD-10 Finland
Congenital cerebral cysts
130.8
12.4
13
*
Z3231
NOMESCO Finland
Registered nurse
1.5
12.4
478
3428
M54.2
ICD-10 Finland
Cervicalgia
2.2
12.4
128
603
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
3.4
12.3
59
178
SPAT1215
SPAT
Assessment of need for medical rehabilitation
2.6
12.2
89
354
A02BC01
ATC
omeprazole; systemic
1.5
12.1
463
3316
N06AX22
ATC
agomelatine; oral
3.6
12.1
54
154
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.2
12.0
128
614
R51.81
ICD-10 Finland
Facial pain NOS
3.8
11.9
50
135
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
1.9
11.9
168
904
T36
ICD-10 Finland
Poisoning by systemic antibiotics
2.4
11.9
101
433
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.8
11.8
215
1261
SHA02
NOMESCO Finland
Correction of physiology of bite - basic therapy visit
2.0
11.8
145
739
N04BC05
ATC
pramipexole; oral
2.2
11.8
117
543
I46.9
ICD-10 Finland
Cardiac arrest, unspecified
9.0
11.7
24
27
XA400
NOMESCO Finland
EEG
9.7
11.7
23
24
Z3226
NOMESCO Finland
Physiotherapist
1.6
11.7
319
2101
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.9
11.7
185
1036
F06.9
ICD-10 Finland
Unspecified mental disorder due to brain damage and dysfunction and to physical disease
16.5
11.7
18
11
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.0
11.5
155
820
AAA20
NOMESCO Finland
Insertion of intraventricular pressure monitoring device
+∞
11.5
11
*
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.5
11.4
401
2811
SPAT1240
SPAT
Therapeutic discussion
1.8
11.4
213
1257
N06AB05
ATC
paroxetine; oral
2.2
11.4
113
525
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.6
11.4
301
1968
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.6
11.4
353
2403
R13
ICD-10 Finland
Dysphagia
2.2
11.3
111
514
R20.2
ICD-10 Finland
Paraesthesia of skin
2.2
11.3
119
570
XF400
NOMESCO Finland
ECG with 12 standard connections
1.7
11.2
266
1688
F41.1
ICD-10 Finland
Generalized anxiety disorder
2.3
11.2
105
473
R18
ICD-10 Finland
Ascites
4.0
11.2
43
108
N06AX26
ATC
vortioxetine; oral
2.2
11.2
120
576
N06BA07
ATC
modafinil; oral
12.8
11.1
19
15
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.1
11.1
127
629
J01FF01
ATC
clindamycin; systemic
1.5
11.0
454
3295
G40.21
ICD-10 Finland
Partial epileptic seizure with cloudiness and automatism
9.3
11.0
22
24
Z02.7
ICD-10 Finland
Issue of medical certificate
2.2
11.0
112
528
FPJ21
NOMESCO Finland
Revision of cardioverter-defibrillator with ventricular electrode
43.5
10.9
13
*
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
6.0
10.9
29
49
N02AA05
ATC
oxycodone; systemic
1.7
10.9
215
1294
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
10.8
439
3170
SPAT1216
SPAT
Assessment of functional ability
1.7
10.8
226
1383
3007
Kela drug reimbursment
Erenumab and fremanezumab
4.6
10.8
36
79
N17.9
ICD-10 Finland
Acute renal failure, unspecified
2.7
10.8
71
265
CK2A4
NOMESCO Finland
Autofluorescence imaging of ocular fundus
9.6
10.7
21
22
H47.2
ICD-10 Finland
Optic atrophy
9.6
10.7
21
22
E66.9
ICD-10 Finland
Obesity, unspecified
2.7
10.7
71
266
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
3.7
10.7
46
128
SPAT1249
SPAT
Treatment-related counselling outside office
1.4
10.7
715
5692
M79.6
ICD-10 Finland
Pain in limb
1.4
10.7
581
4454
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.9
10.6
148
789
G40.10
ICD-10 Finland
Simple partial seizures
6.3
10.6
27
43
P01
ICPC
Feeling anxious/nervous/tense
1.7
10.6
216
1313
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.6
10.6
315
2120
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.8
10.6
169
950
ZY010
NOMESCO Finland
Hospital outpatient
2.2
10.6
107
503
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
10.6
759
6111
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
2.9
10.5
61
212
ZXE20
NOMESCO Finland
More than three and less than five hours
1.7
10.5
221
1356
G93.9
ICD-10 Finland
Disorder of brain, unspecified
+∞
10.4
10
*
A02BA02
ATC
ranitidine; systemic
1.6
10.4
304
2035
N05AB03
ATC
perphenazine; systemic, rectal
2.6
10.4
73
284
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.7
10.4
228
1414
N05BA06
ATC
lorazepam; systemic, sublingual
2.3
10.3
92
407
K72.9
ICD-10 Finland
Hepatic failure, unspecified
8.2
10.3
22
27
N06AB03
ATC
fluoxetine; oral
1.7
10.3
215
1316
F05.9
ICD-10 Finland
Delirium, unspecified
3.9
10.3
41
107
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.6
10.3
300
2007
T82
ICPC
Obesity
2.7
10.3
70
269
P76
ICPC
Depressive disorder
2.0
10.2
124
628
AN1
HP
Coronary angiography
1.8
10.2
169
962
N05CD07
ATC
temazepam; oral
1.8
10.1
188
1111
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
2.5
10.1
78
320
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.6
10.1
298
2003
N06AA09
ATC
amitriptyline; systemic
1.9
10.0
147
799
SPAT1221
SPAT
Guidance concerning rehabilitation services and livelihood
3.9
10.0
40
105
N06AA10
ATC
nortriptyline; systemic
3.5
9.9
45
131
F32.1
ICD-10 Finland
Moderate depressive episode
2.1
9.9
109
530
R26.8
ICD-10 Finland
Other and unspecified abnormalities of gait and mobility
3.7
9.9
42
116
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
4.9
9.9
31
64
R03AC02
ATC
salbutamol; inhalant
1.4
9.9
929
7792
E23.06
ICD-10 Finland
Empty sella
26.1
9.8
13
5
W19
ICD-10 Finland
Unspecified fall
1.8
9.7
160
909
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
2.8
9.7
62
229
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.9
9.7
141
767
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
1.8
9.7
170
987
T85.0
ICD-10 Finland
Mechanical complication of ventricular intracranial (communicating) shunt
55.3
9.6
11
*
Q04.8
ICD-10 Finland
Other specified congenital malformations of brain
55.3
9.6
11
*
H53.9
ICD-10 Finland
Visual disturbance, unspecified
3.0
9.6
55
188
L01AX03
ATC
temozolomide; systemic
7.8
9.6
21
27
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
2.2
9.5
94
436
M53.1
ICD-10 Finland
Cervicobrachial syndrome
1.8
9.5
179
1062
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.4
9.5
448
3331
C09CA06
ATC
candesartan; oral
1.5
9.5
318
2198
B01AA03
ATC
warfarin; systemic
1.6
9.4
278
1865
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.2
9.4
98
466
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.6
9.4
270
1797
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
9.4
591
4630
G95.8
ICD-10 Finland
Other specified diseases of spinal cord
+∞
9.4
9
*
H04.10
ICD-10 Finland
Dry eye syndrome
1.8
9.4
148
830
PA2BD
NOMESCO Finland
Extensive CT angiography of brain
3.6
9.3
40
112
F43.1
ICD-10 Finland
Post-traumatic stress disorder
2.7
9.3
60
224
I25.2
ICD-10 Finland
Old myocardial infarction
2.0
9.3
111
560
A01
ICPC
Pain general/multiple sites
1.9
9.2
125
661
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
3.0
9.2
51
173
TKC20
NOMESCO Finland
Catheterisation of bladder
2.0
9.2
113
578
R4190
NOMESCO Finland
Nutritional therapy
2.4
9.2
76
325
M54.5
ICD-10 Finland
Low back pain
1.4
9.2
538
4159
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.9
9.1
138
759
A04AA01
ATC
ondansetron; systemic, rectal
2.1
9.1
104
516
J45.9
ICD-10 Finland
Asthma, unspecified
1.5
9.1
286
1947
SPAT1252
SPAT
Overall medication plan or its review
2.1
9.1
105
524
AS7
HP
Arrhythmia pacemaker insertion VVI (R) S
15.6
9.0
14
9
Z56.7
ICD-10 Finland
Other and unspecified problems related to employment
9.1
9.0
18
20
ZXY02
NOMESCO Finland
Neuropsychologist
7.1
9.0
21
30
L89
ICD-10 Finland
Decubitus ulcer and pressure area
3.8
9.0
36
95
ZXE10
NOMESCO Finland
More than one and less than three hours
1.4
9.0
582
4571
R52.2
ICD-10 Finland
Other chronic pain
2.5
9.0
68
277
I50.9
ICD-10 Finland
Heart failure, unspecified
1.7
8.9
184
1121
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.4
8.9
538
4175
SPAT1153
SPAT
Removal of sutures
1.4
8.9
489
3730
AAA27
NOMESCO Finland
Insertion of intracerebral pressure monitoring device
24.1
8.9
12
5
N05AA02
ATC
levomepromazine; systemic
2.3
8.9
79
348
H57.1
ICD-10 Finland
Ocular pain
2.7
8.9
60
229
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
4.5
8.8
30
68
F29
ICD-10 Finland
Unspecified nonorganic psychosis
2.2
8.8
84
383
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
3.7
8.8
37
102
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.9
8.8
126
683
R52.9
ICD-10 Finland
Pain, unspecified
1.8
8.8
143
811
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.2
8.8
84
386
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.5
8.8
292
2015
G40
ICD-10 Finland
Epilepsy
5.4
8.7
25
47
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
3.9
8.7
34
88
WX900
NOMESCO Finland
Resuscitation
7.2
8.7
20
28
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
2.2
8.7
84
388
M54.6
ICD-10 Finland
Pain in thoracic spine
2.0
8.7
113
591
PA7BD
NOMESCO Finland
CT angiography of neck and brain
4.5
8.7
29
65
G43.8
ICD-10 Finland
Other migraine
3.6
8.6
37
104
K91
ICPC
Cerebrovascular disease
5.1
8.6
26
52
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
2.1
8.6
93
451
AA1BM
NOMESCO Finland
MRI examination of brain with 3 Tesla magnet
4.3
8.6
30
70
A05
ICPC
Feeling ill
1.9
8.6
118
628
PA2CC
NOMESCO Finland
Cerebral very extensive angiography with X-ray
5.5
8.6
24
44
K07.60
ICD-10 Finland
Snapping jaw
2.1
8.6
97
480
Z3229
NOMESCO Finland
Other healthcare associate professional
1.8
8.5
142
811
G31.2
ICD-10 Finland
Degeneration of nervous system due to alcohol
6.4
8.5
21
33
W79
ICD-10 Finland
Inhalation and ingestion of food causing obstruction of respiratory tract
20.1
8.5
12
6
R40.2
ICD-10 Finland
Coma, unspecified
5.2
8.5
25
49
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
2.0
8.5
99
498
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.7
8.5
186
1156
F10.09
ICD-10 Finland
Alcohol intoxication UNS
2.9
8.4
49
171
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
2.7
8.4
54
201
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.4
8.4
567
4479
SPAT1263
SPAT
Sampling
1.3
8.4
744
6134
N92.6
ICD-10 Finland
Irregular menstruation, unspecified
2.0
8.3
104
535
F60.9
ICD-10 Finland
Personality disorder, unspecified
3.7
8.3
35
97
G91.3
ICD-10 Finland
Post-traumatic hydrocephalus, unspecified
+∞
8.3
8
*
AAF45
NOMESCO Finland
Fenestration of intracranial cyst
+∞
8.3
8
*
WX725
NOMESCO Finland
Noninvasive ventilation
2.2
8.3
79
364
P29
ICPC
Psychological sympt/compl other
1.9
8.3
112
595
N30.0
ICD-10 Finland
Acute cystitis
1.6
8.3
221
1444
M79.1
ICD-10 Finland
Myalgia
1.6
8.2
209
1350
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
4.4
8.2
28
64
G44.0
ICD-10 Finland
Cluster headache syndrome
4.4
8.2
28
64
J01DA01
ATC
[U] cefalexin; systemic
1.3
8.2
1099
9611
F43.29
ICD-10 Finland
Adaptation disorder UNS
3.0
8.2
47
161
M03BC01
ATC
orphenadrine (citrate); systemic
1.4
8.2
382
2823
I61.0
ICD-10 Finland
Intracerebral haemorrhage in hemisphere, subcortical
4.2
8.2
29
69
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
2.4
8.1
64
269
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.0
8.1
100
513
J01MA02
ATC
ciprofloxacin; systemic
1.3
8.1
609
4892
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.7
8.1
171
1052
N02BE01
ATC
paracetamol; systemic, rectal
1.4
8.0
1541
14181
I10
ICD-10 Finland
Essential (primary) hypertension
1.3
8.0
789
6597
AAK00
NOMESCO Finland
Cranioplasty
22.1
8.0
11
5
D33.9
ICD-10 Finland
Benign neoplasm: Central nervous system, unspecified
22.1
8.0
11
5
Z00.0
ICD-10 Finland
General medical examination
1.5
8.0
301
2131
N02CD01
ATC
erenumab; parenteral
4.6
8.0
26
57
ZXE40
NOMESCO Finland
More than seven and less than nine hours
3.1
8.0
42
139
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
3.6
8.0
34
96
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.7
7.9
161
976
UJF32
NOMESCO Finland
Coloscopy
1.4
7.9
363
2675
R69
ICD-10 Finland
Unknown and unspecified causes of morbidity
3.0
7.9
43
146
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
2.2
7.9
75
344
J45.8
ICD-10 Finland
Mixed asthma
2.7
7.9
52
199
P03
ICPC
Feeling depressed
1.7
7.8
170
1051
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
1.9
7.8
116
637
K92.1
ICD-10 Finland
Melaena
2.1
7.8
85
415
P20
ICPC
Memory disturbance
1.8
7.8
138
804
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
2.0
7.8
100
521
I67.6
ICD-10 Finland
Nonpyogenic thrombosis of intracranial venous system
10.8
7.8
14
13
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
1.7
7.8
176
1103
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
4.8
7.8
24
50
K76.7
ICD-10 Finland
Hepatorenal syndrome
15.1
7.7
12
8
127
Kela drug reimbursment
Transplant complication
3.4
7.7
35
104
N05AX12
ATC
aripiprazole; systemic
2.2
7.7
79
375
FPG32
NOMESCO Finland
Implantation of cardioverter-defibrillator with atrial and ventricular electrodes
5.3
7.7
22
42
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.6
7.7
215
1423
R1220
NOMESCO Finland
Psychological examination of need and possibilities to rehabilitation
4.1
7.7
28
69
N31.9
ICD-10 Finland
Neuromuscular dysfunction of bladder, unspecified
5.6
7.7
21
38
E87.6
ICD-10 Finland
Hypokalaemia
2.8
7.7
47
172
E23.00
ICD-10 Finland
Panhypopituitarism
7.4
7.7
17
23
N17
ICPC
Vertigo/dizziness
1.7
7.6
165
1019
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
4.7
7.6
24
51
D35.4
ICD-10 Finland
Benign neoplasm: Pineal gland
25.1
7.6
10
*
ZXC95
NOMESCO Finland
Use of surgical navigator
4.0
7.6
28
70
NA2CG
NOMESCO Finland
Thoracal spine extensive MRI examination with high intensity magnet
5.2
7.5
22
43
H01AC01
ATC
somatropin; parenteral
8.9
7.5
15
17
XX1ZW
NOMESCO Finland
Very extensive written report from radiologist
10.1
7.5
14
14
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
2.6
7.5
53
210
R2120
NOMESCO Finland
Counselling and guidance concerning rehabilitation services and social security
5.4
7.5
21
39
XCK10
NOMESCO Finland
Photography of fundus of eye
1.7
7.5
157
960
XF402
NOMESCO Finland
ECG with work load test
1.7
7.5
149
900
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.5
7.5
256
1772
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
3.6
7.5
32
91
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
3.6
7.5
31
86
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
1.8
7.4
122
692
N03AB02
ATC
phenytoin; systemic
4.4
7.4
25
57
G92
ICD-10 Finland
Toxic encephalopathy
80.4
7.4
8
*
ABB20
NOMESCO Finland
Drainage of intra- or extramedullary cyst of spinal canal
80.4
7.4
8
*
N05BA12
ATC
alprazolam; oral
1.7
7.4
158
976
I50.0
ICD-10 Finland
Congestive heart failure
1.9
7.4
99
526
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
2.7
7.4
47
174
H02AB04
ATC
methylprednisolone; systemic
1.6
7.4
213
1420
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.4
7.3
313
2271
N06AG02
ATC
moclobemide; oral
2.2
7.3
71
328
G90.0
ICD-10 Finland
Idiopathic peripheral autonomic neuropathy
+∞
7.3
7
*
G90.2
ICD-10 Finland
Horner syndrome
+∞
7.3
7
*
Z98.2
ICD-10 Finland
Presence of cerebrospinal fluid drainage device
+∞
7.3
7
*
FPG40
NOMESCO Finland
Replacement of pulse generator in transvenous cardioverter-defibrillator
10.9
7.3
13
12
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.8
7.3
115
644
N07AA02
ATC
pyridostigmine; systemic
9.4
7.3
14
15
G81.9
ICD-10 Finland
Hemiplegia, unspecified
4.9
7.3
22
45
X59
ICD-10 Finland
Exposure to unspecified factor
1.5
7.3
292
2093
J01DB01
ATC
cefalexin; oral
1.3
7.3
1501
13826
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.6
7.3
174
1107
205
Kela drug reimbursment
Chronic hypertension
1.4
7.2
366
2740
J01EA01
ATC
trimethoprim; systemic
1.4
7.2
395
3001
D80.3
ICD-10 Finland
Selective deficiency of immunoglobulin G [IgG] subclasses
15.8
7.2
11
7
N06AX05
ATC
trazodone; oral
2.7
7.2
46
171
G54.0
ICD-10 Finland
Brachial plexus disorders
2.7
7.2
46
171
UGC12
NOMESCO Finland
Flexible bronchoscopy
1.8
7.2
118
671
JDB10
NOMESCO Finland
Percutaneous gastrostomy
4.1
7.2
26
64
T90.5
ICD-10 Finland
Sequelae of intracranial injury
4.1
7.2
26
64
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
2.6
7.2
50
196
N05BE01
ATC
buspirone; oral
2.5
7.2
51
204
D33.07
ICD-10 Finland
Colloid coast in cerebral ventricle
30.1
7.1
9
*
D33.02
ICD-10 Finland
Another benign medial tumor of the cerebrum
30.1
7.1
9
*
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.8
7.1
112
626
NA1AD
NOMESCO Finland
Cervical spine CT examination
2.3
7.1
62
272
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
2.1
7.1
75
361
UJD02
NOMESCO Finland
Gastroscopy
2.1
7.1
75
361
A46
ICD-10 Finland
Erysipelas
1.6
7.1
195
1283
A06AC01
ATC
ispaghula (psylla seeds); oral
1.4
7.1
342
2539
N39.4
ICD-10 Finland
Other specified urinary incontinence
1.9
7.0
104
572
H47.0
ICD-10 Finland
Disorders of optic nerve, not elsewhere classified
7.0
7.0
16
23
RD210
NOMESCO Finland
NA
2.7
7.0
46
176
I21.00
ICD-10 Finland
Acute transmural myocardial infarction of anterior wall
4.1
7.0
25
61
ZXE17
NOMESCO Finland
Procedure duration 150 to 179 minutes
3.6
7.0
29
81
R21
ICPC
Throat symptom/complaint
1.4
7.0
381
2892
M54.1
ICD-10 Finland
Radiculopathy
2.3
6.9
59
259
JN3AD
NOMESCO Finland
Abdominal CT examination
1.8
6.9
109
613
R06AE07
ATC
cetirizine; oral
1.3
6.9
741
6229
M53.0
ICD-10 Finland
Cervicocranial syndrome
1.7
6.9
135
811
G04.9
ICD-10 Finland
Encephalitis, myelitis and encephalomyelitis, unspecified
7.5
6.9
15
20
Z08
ICPC
Social welfare problem
3.9
6.9
26
67
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.6
6.8
159
1004
R5110
SPAT
NA
2.9
6.8
40
142
A02BC03
ATC
lansoprazole; oral
1.4
6.8
425
3297
SPAT1310
SPAT
Counselling related to known health issue
1.3
6.8
525
4215
N06BA04
ATC
methylphenidate; oral
2.3
6.8
57
247
AAK80
NOMESCO Finland
Partial excision of skull cap
40.2
6.8
8
*
S09
ICPC
Infected finger/toe
2.5
6.8
49
199
SPAT1260
SPAT
Consultation of another employee
1.4
6.8
284
2053
E16.2
ICD-10 Finland
Hypoglycaemia, unspecified
3.3
6.7
31
94
P74
ICPC
Anxiety disorder/anxiety state
2.1
6.7
70
336
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
2.3
6.7
60
269
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
3.2
6.7
33
105
101
Kela drug reimbursment
Anterior pituitary hypofunction
4.7
6.7
21
45
R4130
NOMESCO Finland
Speech therapy
2.9
6.7
39
138
P01AB01
ATC
metronidazole; oral, rectal
1.3
6.7
621
5114
R1260
NOMESCO Finland
Evaluation of communicative skills
3.6
6.7
28
79
H93.1
ICD-10 Finland
Tinnitus
1.8
6.7
101
561
N18.8
ICD-10 Finland
Other chronic renal failure
2.6
6.6
44
170
F45.8
ICD-10 Finland
Other somatoform disorders
1.7
6.6
129
776
SPAT1254
SPAT
Administration of medicine
1.5
6.6
229
1591
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
1.7
6.6
132
800
AA4CG
NOMESCO Finland
Extensive MRI examination of sella turcica with high intensity magnet
4.0
6.6
24
60
CS3P4
NOMESCO Finland
Optic nerve head stereophotography
4.0
6.6
24
60
I60.9
ICD-10 Finland
Subarachnoid haemorrhage, unspecified
4.0
6.6
24
60
N05AB04
ATC
prochlorperazine; systemic, rectal
2.9
6.6
36
124
S13.4
ICD-10 Finland
Sprain and strain of cervical spine
2.1
6.6
73
359
N05CF02
ATC
zolpidem; oral
1.5
6.6
263
1885
J96.0
ICD-10 Finland
Acute respiratory failure
3.7
6.6
26
70
ZYC01
NOMESCO Finland
Remote contact by phone
2.0
6.6
84
439
NJ3BG
NOMESCO Finland
MRI examination of extremities with high intensity magnet
8.7
6.5
13
15
A08
ICPC
Swelling
2.3
6.5
56
247
G50.1
ICD-10 Finland
Atypical facial pain
3.2
6.5
32
102
E66.0
ICD-10 Finland
Obesity due to excess calories
4.3
6.5
22
51
N32.83
ICD-10 Finland
Nozzle synergy in the bladder neck
10.0
6.5
12
12
L29
ICPC
Musculoskeletal sympt/complt other
1.8
6.5
107
610
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
1.9
6.5
96
529
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
1.8
6.5
107
611
B01AC04
ATC
clopidogrel; oral
1.6
6.5
183
1212
SPAT1231
SPAT
Assessment of adjustments needed in living environment
3.2
6.5
31
97
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
2.3
6.5
58
260
F33.00
ICD-10 Finland
Recurrent depression, mild episode without somatic syndrome
2.5
6.5
47
191
XCD10
NOMESCO Finland
Electrophysiological examination of eye
2.5
6.5
47
191
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.1
6.5
68
328
B81
ICPC
Anaemia vit B12/folate deficiency
2.3
6.5
55
240
AA5BD
NOMESCO Finland
CT of cerebral ischaemia
3.3
6.5
30
92
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.3
6.4
478
3811
D44.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Pineal gland
70.1
6.4
7
*
G96.9
ICD-10 Finland
Disorder of central nervous system, unspecified
70.1
6.4
7
*
G90.9
ICD-10 Finland
Disorder of autonomic nervous system, unspecified
70.1
6.4
7
*
G40.19
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
4.3
6.4
22
52
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.6
6.4
153
974
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
1.8
6.4
104
590
A29
ICPC
General symptom/complaint other
1.6
6.4
162
1045
H52.2
ICD-10 Finland
Astigmatism
3.1
6.4
32
104
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
2.4
6.4
52
224
C09AA02
ATC
enalapril; systemic
1.4
6.4
267
1932
N02CD03
ATC
fremanezumab; systemic
4.9
6.4
19
39
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.0
6.3
76
387
NXL00
NOMESCO Finland
Biopsy of muscle
8.2
6.3
13
16
R27.0
ICD-10 Finland
Ataxia, unspecified
8.2
6.3
13
16
JCA22
NOMESCO Finland
Endoscopic ligature of oesophageal varices
8.2
6.3
13
16
81
HP
Angiography of the heart and coronary arteries
1.9
6.3
86
459
N05AD01
ATC
haloperidol; systemic
2.3
6.3
55
246
A86
ICD-10 Finland
Unspecified viral encephalitis
6.0
6.3
16
27
C71.10
ICD-10 Finland
Malignant tumor in frontal lobe without histology
11.1
6.3
11
10
F41.00
ICD-10 Finland
Moderate panic disorder
2.8
6.3
37
133
AAD10
NOMESCO Finland
Evacuation of chronic subdural haematoma
3.7
6.3
25
68
R33
ICD-10 Finland
Retention of urine
1.7
6.3
112
657
I42.0
ICD-10 Finland
Dilated cardiomyopathy
2.5
6.3
45
182
G46.4*I67.9
ICD-10 Finland
Cerebellar stroke syndrome
+∞
6.3
6
*
YFA50
NOMESCO Finland
Excision of heart for preparation of homograft
+∞
6.3
6
*
G96.0
ICD-10 Finland
Cerebrospinal fluid leak
+∞
6.3
6
*
F34.1
ICD-10 Finland
Dysthymia
2.1
6.2
64
306
S97
ICPC
Chronic ulcer skin
2.0
6.2
75
383
N31.1
ICD-10 Finland
Reflex neuropathic bladder, not elsewhere classified
7.0
6.2
14
20
UKC02
NOMESCO Finland
Cystoscopy
1.5
6.2
224
1569
I67.1
ICD-10 Finland
Cerebral aneurysm, nonruptured
2.9
6.2
34
118
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
2.9
6.2
34
118
Z31.5
ICD-10 Finland
Genetic counselling
1.9
6.2
89
486
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
2.3
6.2
51
222
G04BD07
ATC
tolterodine; oral
2.1
6.2
68
335
G03.9
ICD-10 Finland
Meningitis, unspecified
6.3
6.2
15
24
N93.9
ICD-10 Finland
Abnormal uterine and vaginal bleeding, unspecified
2.8
6.1
36
129
R06.4
ICD-10 Finland
Hyperventilation
3.0
6.1
33
113
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
2.3
6.1
53
235
Z94.4
ICD-10 Finland
Liver transplant status
7.7
6.1
13
17
N30.9
ICD-10 Finland
Cystitis, unspecified
1.9
6.1
85
460
XF602
NOMESCO Finland
Bloodpressure monitoring
4.2
6.1
21
50
F33.30
ICD-10 Finland
Recurrent depression, severe episode without somatic syndrome
3.6
6.1
25
70
F06.8
ICD-10 Finland
Other specified mental disorders due to brain damage and dysfunction and to physical disease
12.6
6.1
10
8
Q07.0
ICD-10 Finland
Arnold-Chiari syndrome
8.6
6.1
12
14
J01CA08
ATC
pivmecillinam; oral
1.3
6.1
612
5086
D32.02
ICD-10 Finland
Benign tumor of the meninges at the base of the brain
4.9
6.0
18
37
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.5
6.0
185
1252
G04BD04
ATC
oxybutynin; oral, transdermal
2.0
6.0
74
383
L17
ICPC
Foot/toe symptom/complaint
1.4
6.0
371
2870
JA2AT
NOMESCO Finland
Abdominal puncture with ultrasound guidance
4.1
6.0
21
51

Mortality – FinRegistry

Association

Association between endpoint G6_CERCYST and mortality.

Females

Parameter HR [95% CI] p-value
G6_CERCYST 3.663 [3.19, 4.21] < 0.001
Birth year 0.992 [0.98, 1.0] 0.072

During the follow-up period (1.1.1998 — 31.12.2019), 1185 out of 5799 females with G6_CERCYST died.

Males

Parameter HR [95% CI] p-value
G6_CERCYST 3.775 [3.36, 4.24] < 0.001
Birth year 0.989 [0.98, 1.0] 0.013

During the follow-up period (1.1.1998 — 31.12.2019), 2063 out of 6201 males with G6_CERCYST died.

Mortality risk

Mortality risk for people of age

years, who have G6_CERCYST.

N-year risk Females Males
1 0.347% 0.85%
5 2.303% 4.934%
10 5.1% 11.518%
15 9.267% 21.045%
20 15.851% 33.472%

Relationships between endpoints

Index endpoint: G6_CERCYST – Cerebral cysts

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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