This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

G6_AUTONOM

Autonomic dysreflexia

EFO Endpoint Browser

G6_AUTODYS

No definition available.

Suggest a new description

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — G90.4 Cause of death: ICD-10 — G90.4 2 out of 7 registries used, show all original rules.	14
4. Check minimum number of events None	14
5. Include endpoints None	14
6. Filter based on genotype QC (FinnGen only)	14

Control definitions (FinnGen only)

Control exclude: G6_AUTONOM

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: G90

NAME	G6_AUTODYS
CONTROL_EXCLUDE	G6_AUTONOM
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	G904
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	G904
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Autonomic dysreflexia based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	53	28	25
Only index persons	53	28	25
Unadjusted period prevalence (%)
Whole population	0.00	0.00	0.00
Only index persons	0.00	0.00	0.00
Median age at first event (years)
Whole population	-	48.59	54.84
Only index persons	51.54	48.59	54.84

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	14	11	-
Unadjusted period prevalence (%)	0.00	0.00	-
Median age at first event (years)	52.36	48.55	-

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

No data available

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

unit

cases

controls

-log₁₀(p)

N cases

N controls

(3017766) Complement C4 [Mass/volume] in Serum or Plasma

16.06

3.91

1.3

1.0

g/l

0.2

—

(3000620) Complement C3 [Mass/volume] in Serum or Plasma

16.06

3.91

1.3

1.0

g/l

1.3

—

(42870588) Differential panel, method unspecified - Blood

7.40

3.15

6.1

6.3

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

9.48

3.05

4.8

4.2

—

(3033658) Prothrombin time (PT) actual/Normal

6.66

2.84

4.1

4.0

95.9

99.6

—

(3022948) Iron [Moles/volume] in Serum or Plasma

6.65

2.68

2.6

2.9

umol/l

14.1

12.0

—

(3026782) Osmolality of Urine

5.76

2.53

14.8

2.0

mosm/kgh2o

462.1

523.3

—

(3042936) Bacteria identified in Isolate by Culture

6.61

2.46

2.0

1.4

—

(40758558) Short blood count panel - Blood

5.57

2.35

9.7

4.9

—

(3030467) Casts [#/volume] in Urine by Automated count

5.26

2.35

13.2

2.3

e6/l

0.3

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

7.06

2.28

22.4

2.4

e6/l

5.4

0.7

—

(36304419) Bacteria [Presence] in Urine

5.03

2.26

13.0

2.2

—

(3026008) Bacteria identified in Urine by Culture

4.63

2.10

17.1

2.2

—

(3002582) Erythrocytes [#/volume] in Urine

4.45

2.02

20.9

2.4

e6/l

13.9

121.2

—

(40768797) Stomach Pathology biopsy report

4.25

1.59

2.0

1.4

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

3.67

1.56

21.1

2.8

—

(3018095) Leukocytes [#/volume] in Urine

3.67

1.56

32.1

3.1

e6/l

53.6

42.9

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

2.97

1.08

1.7

—

(3023368) Bacteria identified in Blood by Culture

2.85

1.05

11.7

4.0

—

(40760892) CBC W Ordered Manual Differential panel - Blood

2.85

1.05

3.7

8.1

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

113

+∞

0.88

5.6

4.2

mu/l

1.3

1.9

1.50

103

(3015736) pH of Urine

2.31

0.81

4.5

2.6

—

(3041096) Erythrocytes [Presence] in Urine by Automated

2.24

0.69

16.5

2.9

—

(40768804) Tissue Pathology biopsy report

1.93

0.58

1.5

1.8

—

(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma

0.00

0.44

0.0

4.4

—

1.2

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

1.85

0.42

14.4

2.6

—

(3044640) Blood type and Crossmatch panel - Blood

1.54

0.28

2.8

2.4

—

(3019225) pH of Specimen

0.00

0.22

0.0

12.7

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

0.00

0.22

0.0

4.8

—

(21494755) Public health laboratory ask at order entry panel

0.00

0.21

0.0

1.3

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

0.00

0.0

1.3

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

1.09

0.00

5.5

3.9

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.1

—

(1761868) Lipid panel - Serum or Plasma

0.97

0.00

1.8

2.4

—

(3050129) First trimester maternal screen panel - Serum or Plasma

0.00

0.0

1.4

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

0.00

0.0

4.1

—

(3027008) Opiates [Presence] in Urine

0.00

0.0

1.5

—

(40758310) Human epididymis protein 4 [Moles/volume] in Serum or Plasma

0.00

0.0

1.2

—

72.2

—

(3028300) Cannabinoids [Presence] in Urine

0.00

0.0

1.5

—

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

3.6

—

(40768793) Breast Pathology biopsy report

0.00

0.0

1.2

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

0.00

0.0

1.0

—

(40761535) Cells panel - Urine sediment

0.00

0.0

3.0

—

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

0.00

0.0

3.7

—

(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay

0.00

0.0

1.7

—

(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells

0.00

0.0

2.0

—

(3007778) Kappa light chains/Lambda light chains [Mass Ratio] in Serum

0.00

0.0

1.4

—

(3025130) Human papilloma virus identified in Specimen

0.00

0.0

2.0

—

(3027944) Amphetamines [Presence] in Urine

0.00

0.0

1.3

—

(3019539) Treponema pallidum Ab [Titer] in Serum by Hemagglutination

0.00

0.0

1.4

—

(3000764) Benzodiazepines [Presence] in Urine

0.00

0.0

1.4

—

Mortality – FinRegistry

↥

Association

Association between endpoint G6_AUTODYS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have G6_AUTODYS.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: G6_AUTODYS – Autonomic dysreflexia

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

Extremity

rg [CI]

Extremity

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Autonomic dysreflexia

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints