No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersNone 0 out of 7 registries used, show all original rules. |
0 |
4. Check minimum number of eventsNone |
0 |
5. Include endpoints |
13250 |
6. Filter based on genotype QC (FinnGen only) |
13250 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- First used in FinnGen datafreeze
- DF7
Similar endpoints
↥List of similar endpoints to
Nontoxic goitre/thyroid nodule
based on the number of shared cases.
Similar with more cases:
- Disorders of the thyroid gland
- Used for control exclusion in common control thyroid runs
- Endocrine, nutritional and metabolic diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 94629 | 79516 | 14590 |
| Only index persons | 83422 | 70990 | 12432 |
| Unadjusted period prevalence (%) | |||
| Whole population | 1.98 | 2.28 | 0.41 |
| Only index persons | 2.29 | 2.61 | 0.47 |
| Median age at first event (years) | |||
| Whole population | 53.07 | 52.37 | 56.86 |
| Only index persons | 52.03 | 51.30 | 56.19 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 13250 | 11038 | 2212 |
| Unadjusted period prevalence (%) | 3.30 | 3.76 | 0.98 |
| Median age at first event (years) | 51.93 | 50.45 | 59.30 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 11873
- Matched controls
- 118730
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
BA3AT
NOMESCO Finland
Cytology of thyroid with ultrasound quidance
22.7
323.0
1055
508
E04.8
ICD-10 Finland
Other specified nontoxic goitre
160.9
323.0
359
23
E04.0
ICD-10 Finland
Nontoxic diffuse goitre
315.3
323.0
979
34
2504
FHL
Unilateral resection or enucleation
79.8
323.0
691
92
E04.2
ICD-10 Finland
Nontoxic multinodular goitre
616.6
323.0
6070
201
BAA40
NOMESCO Finland
Unilateral lobectomy of thyroid gland
87.8
323.0
2676
392
E89.01
ICD-10 Finland
Postsurgical hypothyroidism
23.8
323.0
1103
509
BAA60
NOMESCO Finland
Total thyroidectomy
28.2
323.0
1800
749
E04.1
ICD-10 Finland
Nontoxic single thyroid nodule
315.4
323.0
2293
90
2411A
ICD-9 Finland
Non-toxic nodular goitre, Non-toxic multinodular goitre
+∞
323.0
501
*
2419X
ICD-9 Finland
Non-toxic nodular goitre, Unspecified non-toxic nodular goitre
+∞
323.0
369
*
104
Kela drug reimbursment
Thyroid insufficiency
5.9
323.0
2619
5425
D44.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Thyroid gland
15.0
323.0
710
501
2505
FHL
Bilateral resection (also used if total removal has been performed on the other side)
41.1
323.0
549
140
BAA20
NOMESCO Finland
Unilateral partial excision of thyroid gland
156.4
323.0
364
24
EP1AE
NOMESCO Finland
Neck ultrasound examination
6.1
323.0
1662
3101
E04.9
ICD-10 Finland
Nontoxic goitre, unspecified
140.6
323.0
2790
259
24199
ICD-8 Finland
Non-toxic nodular goitre, Unspecified
+∞
323.0
1156
*
BA1AE
NOMESCO Finland
Thyroiid ultrasound examination
18.1
323.0
892
530
H03AA01
ATC
levothyroxine sodium; systemic
4.4
323.0
5879
21753
2410A
ICD-9 Finland
Non-toxic nodular goitre, Non-toxic uninodular goitre
+∞
304.4
291
*
C73.91
ICD-10 Finland
Papillary carcinoma of the thyroid gland (thyroid gland)
11.0
289.0
573
545
E05.2
ICD-10 Finland
Thyrotoxicosis with toxic multinodular goitre
10.3
259.6
531
535
24110
ICD-8 Finland
Non-toxic nodular goitre, Sporadic
+∞
255.1
244
*
8260/3-C73.9
ICD-O-3
Papillary adenocarcinoma, NOS, of thyroid gland
10.4
244.6
498
497
D34
ICD-10 Finland
Benign neoplasm of thyroid gland
16.6
235.4
387
240
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
7.9
206.6
493
645
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
2.3
201.6
2129
10175
BAA25
NOMESCO Finland
Bilateral partial excision of thyroid gland
97.2
189.8
210
22
T81
ICPC
Goitre
26.4
171.2
241
93
E04
ICD-10 Finland
Other nontoxic goitre
27.5
143.8
200
74
E03.89
ICD-10 Finland
Other specified hypothyroidism
3.4
133.8
701
2152
BAA50
NOMESCO Finland
Lobectomy and resection of contralateral lobe of thyroid gland
57.0
118.7
141
25
24099
ICD-8 Finland
Simple goitre, Unspecified
+∞
117.9
113
*
R22.1
ICD-10 Finland
Localized swelling, mass and lump, neck
3.4
115.4
600
1828
H03BB01
ATC
carbimazole; oral
3.0
109.9
677
2329
E89.2
ICD-10 Finland
Postprocedural hypoparathyroidism
17.3
109.5
176
103
24100
ICD-8 Finland
Non-toxic nodular goitre, Endemic
+∞
106.4
102
*
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
101.8
3108
21123
T86
ICPC
Hypothyroidism/myxoedema
2.8
98.6
668
2443
ZXE10
NOMESCO Finland
More than one and less than three hours
1.5
96.2
4310
32122
C73.92
ICD-10 Finland
Follicular carcinoma of the thyroid gland
23.3
94.9
138
60
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.6
94.8
756
3045
N02BE01
ATC
paracetamol; systemic, rectal
1.7
90.7
10195
92862
E03
ICD-10 Finland
Other hypothyroidism
2.3
90.1
934
4302
XX7CT
NOMESCO Finland
Radioiodine therapy of thydoid tissue
6.5
90.1
243
379
JN5PN
NOMESCO Finland
Isotope imaging of secondary neoplasms of thyroid origin
11.8
88.6
167
143
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.5
87.7
4517
34517
2462A
ICD-9 Finland
Other disorders of thyroid, Cyst of thyroid
+∞
83.4
80
*
R13
ICD-10 Finland
Dysphagia
2.3
83.2
845
3853
106
Kela drug reimbursment
Hypoparathyroidism
12.4
79.8
147
120
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.6
74.8
2468
16882
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
72.8
2448
16803
E05.80
ICD-10 Finland
Subacute thyrotoxicosis
6.3
72.1
199
321
TBA20
NOMESCO Finland
Aspiration cytology of thyroid gland
112.2
71.9
78
7
T72
ICPC
Benign neoplasm thyroid
13.9
66.6
116
84
E05.9
ICD-10 Finland
Thyrotoxicosis, unspecified
2.9
64.7
416
1467
8330/3-C73.9
ICD-O-3
Follicular carcinoma, NOS, of thyroid gland
21.8
63.0
93
43
BA1AE
SPAT
NA
7.5
62.4
152
206
BAA30
NOMESCO Finland
Excision of thyroid isthmus
41.3
62.2
78
19
GB1AA
NOMESCO Finland
Tracheal X-ray examination
50.3
62.1
75
15
A11CC03
ATC
alfacalcidol; systemic
3.3
58.4
306
936
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
3.9
57.1
244
632
C73.90
ICD-10 Finland
Malignant tumor of the thyroid gland (thyroid gland) without histology
10.7
56.8
112
106
A02BC05
ATC
esomeprazole; systemic
1.4
55.2
4647
37901
R03AC02
ATC
salbutamol; inhalant
1.3
53.2
5787
49091
ZXD10
NOMESCO Finland
Scheduled procedure
1.4
52.9
4316
34944
ZXA05
NOMESCO Finland
Left side
1.4
52.6
2907
21964
ZXA00
NOMESCO Finland
Right side
1.4
52.3
3092
23654
E83.51
ICD-10 Finland
Hypocalcemia
6.9
51.8
132
192
BBA30
NOMESCO Finland
Excision of lesion of parathyroid gland
3.8
50.4
220
582
E21.09
ICD-10 Finland
Other primary hyperparathyroidism
3.0
50.3
303
1025
E05.0
ICD-10 Finland
Thyrotoxicosis with diffuse goitre
2.5
49.4
401
1625
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
49.4
3809
30451
A11CC02
ATC
dihydrotachysterol; oral
10.5
49.0
97
93
2506
FHL
Thyroidectomy
11.3
47.3
90
80
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.4
46.3
3179
24855
XW1AT
NOMESCO Finland
Biopsy from other organ close to skin with ultrasound quidance
6.1
44.7
125
207
R07.4
ICD-10 Finland
Chest pain, unspecified
1.4
42.7
2904
22607
JN5AQ
NOMESCO Finland
SPECT of thyroid metastasis with low-dose CT
11.7
41.8
78
67
R49.01
ICD-10 Finland
Functional dysphonia
2.3
41.7
396
1739
R06.0
ICD-10 Finland
Dyspnoea
1.4
40.1
2688
20832
R01AD09
ATC
mometasone; nasal
1.3
39.7
4744
40128
J01DB01
ATC
cefalexin; oral
1.3
39.0
8980
83009
A02BC02
ATC
pantoprazole; systemic
1.3
38.6
7293
65505
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.3
37.1
4544
38449
EN1AD
NOMESCO Finland
CT examination of mouth and soft tissues of neck
4.5
37.0
133
295
C07AB07
ATC
bisoprolol; oral
1.3
36.5
5040
43296
C73
ICD-10 Finland
Malignant neoplasm of thyroid gland
7.6
36.2
86
114
BWD00
NOMESCO Finland
Reoperation for deep haemorrhage in endocrine surgery
28.3
35.4
48
17
4CJ01
NOMESCO Finland
NA
9.3
35.3
74
80
E07.9
ICD-10 Finland
Disorder of thyroid, unspecified
8.1
35.2
80
99
E05.1
ICD-10 Finland
Thyrotoxicosis with toxic single thyroid nodule
9.6
34.1
70
73
E89.09
ICD-10 Finland
Postprocedural hypothyroidism, other or several procedures
7.5
33.5
80
107
C73.99
ICD-10 Finland
Malignant tumor of the thyroid gland (thyroid gland), other or unspecified histology
7.9
33.3
77
98
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
2.2
32.9
352
1638
J01FA10
ATC
azithromycin; systemic
1.3
32.7
6078
53891
8341/3-C73.9
ICD-O-3
Papillary microcarcinoma of thyroid gland
22.5
32.6
47
21
UJF32
NOMESCO Finland
Coloscopy
1.3
32.2
2744
21961
G47.3
ICD-10 Finland
Sleep apnoea
1.4
31.8
1768
13196
J01AA02
ATC
doxycycline; systemic
1.3
31.7
8808
81906
R21
ICPC
Throat symptom/complaint
1.4
31.6
1725
12829
WX402
NOMESCO Finland
General anaesthesia
1.4
31.6
1591
11662
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.4
31.2
2177
16880
BA2AT
NOMESCO Finland
Biopsy of thyroid with ultrasound quidance
19.7
31.2
47
24
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.5
30.9
1044
7047
QX3LT
NOMESCO Finland
Subcutaneous sclerotherapy
20.5
30.3
45
22
R07.0
ICD-10 Finland
Pain in throat
1.8
30.3
567
3263
2400A
ICD-9 Finland
Simple and unspecified goitre, Goitre, specified as simple
+∞
30.2
29
*
M79.6
ICD-10 Finland
Pain in limb
1.3
29.9
3831
32332
EP1AE
SPAT
NA
3.4
29.4
145
428
ZX114
NOMESCO Finland
Intramuscular
2.8
29.0
189
675
J01FA06
ATC
roxithromycin; oral
1.3
28.7
4348
37399
R49.08
ICD-10 Finland
Other specified dysphonia
2.3
28.7
262
1133
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
28.7
3991
33985
J37.0
ICD-10 Finland
Chronic laryngitis
2.1
28.4
338
1650
BAA99
NOMESCO Finland
Other operation on thyroid gland
26.1
28.3
39
15
ZXA10
NOMESCO Finland
Bilateral
1.3
28.0
2014
15659
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.5
27.8
1016
6973
S18
ICPC
Laceration/cut
1.3
27.7
4330
37340
J45.9
ICD-10 Finland
Asthma, unspecified
1.4
27.3
1825
14024
R42
ICD-10 Finland
Dizziness and giddiness
1.3
27.2
2354
18803
N02AX02
ATC
tramadol; systemic, rectal
1.2
27.2
4306
37167
R53
ICD-10 Finland
Malaise and fatigue
1.3
27.0
2050
16066
M25.5
ICD-10 Finland
Pain in joint
1.3
26.9
2912
23976
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
1.6
26.9
688
4334
ZSB00
NOMESCO Finland
Procedure related to previous procedure classified in chapter B
20.1
26.9
40
20
E07.89
ICD-10 Finland
Other specified disorders of thyroid
13.6
26.7
46
34
I10
ICD-10 Finland
Essential (primary) hypertension
1.2
26.4
6263
56455
M54.5
ICD-10 Finland
Low back pain
1.3
26.2
3310
27779
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.4
26.1
1672
12751
E06.3
ICD-10 Finland
Autoimmune thyroiditis
4.1
25.8
103
255
A02BA02
ATC
ranitidine; systemic
1.3
25.7
2085
16485
M03BX02
ATC
tizanidine; oral
1.2
25.6
6515
59064
A06AC01
ATC
ispaghula (psylla seeds); oral
1.3
25.4
2731
22440
T71
ICPC
Malignant neoplasm thyroid
9.6
24.6
50
52
2409X
ICD-9 Finland
Simple and unspecified goitre, Goitre, unspecified
13.6
24.4
42
31
E89.0
ICD-10 Finland
Postprocedural hypothyroidism
8.6
24.4
53
62
A12AA04
ATC
calcium carbonate; oral
2.8
24.3
162
589
G44.2
ICD-10 Finland
Tension-type headache
1.4
24.2
1348
10028
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.4
24.1
1161
8413
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.4
24.0
1154
8362
M01AE02
ATC
naproxen; oral, rectal
1.2
23.6
5853
52711
R51.80
ICD-10 Finland
Headache
1.4
23.4
1381
10370
EP2AT
NOMESCO Finland
Neck soft tissue cytology with ultrasound guidance
6.4
23.4
62
98
T85
ICPC
Hyperthyroidism/thyrotoxicosis
4.1
23.1
90
219
24010
ICD-8 Finland
Simple goitre, Sporadic
+∞
22.9
22
*
BA1NN
NOMESCO Finland
I-131 dose capsel measurement
9.1
22.9
48
53
A02BC03
ATC
lansoprazole; oral
1.2
22.7
3130
26449
S04
ICPC
Lump/swelling localized
1.5
22.6
869
6021
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.3
22.6
2362
19293
DQE10
NOMESCO Finland
Injection of foreign material into vocal cord
6.7
22.5
57
85
SPAT1153
SPAT
Removal of sutures
1.2
22.4
3311
28190
T15
ICPC
THYROID LUMP/MASS
11.4
22.1
41
36
J01DA01
ATC
[U] cefalexin; systemic
1.2
21.7
6650
60923
J01FA09
ATC
clarithromycin; systemic
1.2
21.0
3183
27126
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.2
21.0
4631
41043
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.3
21.0
2144
17439
M54.4
ICD-10 Finland
Lumbago with sciatica
1.3
20.9
1583
12355
M01AE03
ATC
ketoprofen; systemic, rectal
1.2
20.8
3886
33862
UKC02
NOMESCO Finland
Cystoscopy
1.4
20.7
1283
9709
C07AB02
ATC
metoprolol; systemic
1.3
20.3
2079
16901
Z50.5
ICD-10 Finland
Speech therapy
2.8
20.3
134
487
GD6BD
NOMESCO Finland
Extensive CT of chest and neck
7.0
20.3
50
72
A02BC01
ATC
omeprazole; systemic
1.2
20.1
2851
24106
R03DC03
ATC
montelukast; oral
1.3
20.0
1583
12427
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.2
20.0
3210
27504
E21.0
ICD-10 Finland
Primary hyperparathyroidism
2.3
20.0
183
797
H02AB06
ATC
prednisolone; systemic
1.2
19.9
4804
42870
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.2
19.8
4766
42515
B01AB05
ATC
enoxaparin; parenteral
1.2
19.6
3181
27276
BA3AT
SPAT
NA
21.6
19.4
28
13
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.3
19.2
2250
18589
E06.9
ICD-10 Finland
Thyroiditis, unspecified
4.9
19.2
63
130
N03AX16
ATC
pregabalin; oral
1.3
19.1
2408
20061
GAB20
NOMESCO Finland
Median sternotomy
22.5
19.0
27
12
J02AC01
ATC
fluconazole; systemic
1.2
19.0
4561
40618
J01MA02
ATC
ciprofloxacin; systemic
1.2
19.0
3774
33006
WZC30
NOMESCO Finland
Teaching
1.4
18.9
1209
9183
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
1.3
18.8
1857
15009
N03AX12
ATC
gabapentin; oral
1.3
18.8
1529
12044
A02BC04
ATC
rabeprazole; oral
1.4
18.7
827
5891
Z71.8
ICD-10 Finland
Other specified counselling
1.3
18.6
2206
18243
R01AD12
ATC
fluticasone furoate; nasal
1.2
18.6
2739
23218
M01AC06
ATC
meloxicam; systemic, rectal
1.2
18.5
3943
34704
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.2
18.3
3894
34253
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
2.6
18.2
130
498
R52.9
ICD-10 Finland
Pain, unspecified
1.4
18.0
801
5707
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.3
18.0
1678
13458
SAA01
NOMESCO Finland
Simple examination of mouth
1.2
17.9
7064
65635
R4130
NOMESCO Finland
Speech therapy
2.1
17.9
200
956
R02
ICPC
Shortness of breath/dyspnoea
1.3
17.9
1149
8731
R01AD08
ATC
fluticasone; nasal
1.2
17.9
2766
23553
L01
ICPC
Neck symptom/complaint
1.3
17.9
1336
10394
UDH02
NOMESCO Finland
Rhinopharyngoscopy
1.5
17.8
561
3718
H04.10
ICD-10 Finland
Dry eye syndrome
1.4
17.8
1010
7521
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
3.0
17.8
104
352
ZXE20
NOMESCO Finland
More than three and less than five hours
1.3
17.6
1248
9629
8340/3-C73.9
ICD-O-3
Papillary carcinoma, follicular variant of thyroid gland
12.4
17.5
31
25
D25.9
ICD-10 Finland
Leiomyoma of uterus, unspecified
1.4
17.5
948
7003
2440A
ICD-9 Finland
Acquired hypothyroidism, Postsurgical hypothyroidism
15.6
17.4
28
18
SPAT1249
SPAT
Treatment-related counselling outside office
1.2
17.3
3966
35081
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.3
17.2
1174
9001
E06.1
ICD-10 Finland
Subacute thyroiditis
3.1
17.2
96
315
M01AB05
ATC
diclofenac; systemic, rectal
1.2
17.2
6949
64575
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.2
17.1
4963
44820
SPAT1263
SPAT
Sampling
1.2
16.8
4301
38396
R05
ICD-10 Finland
Cough
1.3
16.8
1926
15844
C07AA05
ATC
propranolol; systemic
1.3
16.7
1851
15167
XKD00
NOMESCO Finland
Uroflowmetry
1.4
16.6
897
6626
M01AE01
ATC
ibuprofen; systemic, rectal
1.2
16.4
9756
93692
2509
FHL
Other measure in this category
23.0
16.4
23
10
M02AA07
ATC
piroxicam; topical
1.2
16.3
3945
35006
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.3
16.3
1619
13081
I49.3
ICD-10 Finland
Ventricular premature depolarization
1.5
16.2
611
4211
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
1.4
16.2
1017
7696
ZXE00
NOMESCO Finland
One hour or less
1.2
16.1
3930
34900
A12AA06
ATC
calcium lactate gluconate; oral
7.0
16.0
39
56
C08CA01
ATC
amlodipine; oral
1.2
15.9
3536
31122
L15
ICPC
Knee symptom/complaint
1.2
15.9
2124
17763
E20.8
ICD-10 Finland
Other hypoparathyroidism
10.0
15.9
31
31
WX704
NOMESCO Finland
Intubation
1.5
15.8
619
4303
R01BA52
ATC
pseudoephedrine, combinations; oral
1.2
15.8
3254
28435
R05FA02
ATC
opium derivatives and expectorants; systemic
1.2
15.8
4262
38162
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
1.5
15.7
593
4091
R49.8
ICD-10 Finland
Other and unspecified voice disturbances
2.5
15.7
122
491
F45.8
ICD-10 Finland
Other somatoform disorders
1.5
15.7
543
3677
R00.2
ICD-10 Finland
Palpitations
1.4
15.5
673
4776
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.2
15.5
2394
20331
K30
ICD-10 Finland
Functional dyspepsia
1.3
15.5
1017
7750
SPAT1325
SPAT
Vaccination
1.2
15.3
3506
30921
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.2
15.1
1819
15028
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
1.5
15.1
446
2916
E66.01
ICD-10 Finland
Obesity due to excess calories
1.4
15.0
636
4497
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
1.5
15.0
566
3909
E89.00
ICD-10 Finland
Postirradiation hypothyroidism
2.5
14.9
113
448
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.3
14.9
1258
9942
E21.3
ICD-10 Finland
Hyperparathyroidism, unspecified
2.3
14.9
130
557
Z3231
NOMESCO Finland
Registered nurse
1.2
14.9
2562
21983
XF404
NOMESCO Finland
Ambulatory ECG
1.4
14.8
820
6076
R05FB02
ATC
cough suppressants and expectorants
1.2
14.7
4011
35889
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.2
14.6
6206
57515
E03.0
ICD-10 Finland
Congenital hypothyroidism with diffuse goitre
2.8
14.6
95
344
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
1.4
14.6
594
4165
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.2
14.5
5375
49270
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.2
14.5
2224
18860
R03BA05
ATC
fluticasone; inhalant
1.2
14.4
1722
14216
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
1.3
14.3
1090
8488
WX110
NOMESCO Finland
Local anesthesy
1.2
14.3
6909
64621
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
2.5
14.3
112
452
M03BC51
ATC
orphenadrine, combinations; systemic
1.2
14.3
2738
23726
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.2
14.2
2861
24903
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.3
14.2
1135
8898
J01CA04
ATC
amoxicillin; systemic
1.2
14.1
8525
81138
M01AH01
ATC
celecoxib; oral (coxibs)
1.2
14.1
1868
15595
M01AH05
ATC
etoricoxib; oral
1.2
13.9
6020
55773
N06AX11
ATC
mirtazapine; oral
1.2
13.8
3126
27490
M01AX17
ATC
nimesulide; oral
1.2
13.7
2556
22077
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.3
13.7
946
7263
JC2KB
NOMESCO Finland
Functional X-ray examination of swallowing
2.4
13.6
117
496
GD6AD
NOMESCO Finland
CT of chest and neck
4.7
13.5
45
96
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
1.3
13.5
869
6602
L03
ICPC
Low back symptom/complaint
1.2
13.5
2362
20276
N40
ICD-10 Finland
Hyperplasia of prostate
1.3
13.5
875
6656
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.4
13.5
741
5486
XF402
NOMESCO Finland
ECG with work load test
1.3
13.5
993
7701
M54.6
ICD-10 Finland
Pain in thoracic spine
1.4
13.4
576
4082
D25.1
ICD-10 Finland
Intramural leiomyoma of uterus
1.4
13.4
606
4336
E20.9
ICD-10 Finland
Hypoparathyroidism, unspecified
6.4
13.3
34
53
N02AJ06
ATC
codeine and paracetamol; systemic
1.2
13.3
3458
30748
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.2
13.3
4581
41663
K80
ICPC
Cardiac arrhythmia NOS
1.4
13.2
705
5198
M70.6
ICD-10 Finland
Trochanteric bursitis
1.3
13.1
1377
11180
L28
ICPC
Limited function/disability (L)
1.2
13.1
1529
12571
P01AB01
ATC
metronidazole; oral, rectal
1.2
13.1
4152
37496
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.2
13.1
1866
15683
C09CA01
ATC
losartan; oral
1.2
13.1
2338
20100
D24
ICD-10 Finland
Benign neoplasm of breast
1.8
12.9
213
1185
M03BC01
ATC
orphenadrine (citrate); systemic
1.2
12.9
2105
17943
J01EA01
ATC
trimethoprim; systemic
1.2
12.9
2870
25178
A01AB09
ATC
miconazole; local oral
1.3
12.8
905
6967
B02AA02
ATC
tranexamic acid; systemic
1.2
12.8
1498
12319
R06.5
ICD-10 Finland
Mouth breathing
1.4
12.8
617
4469
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
1.4
12.7
598
4310
J01FF01
ATC
clindamycin; systemic
1.2
12.7
2501
21693
C05AA08
ATC
fluocortolone; rectal, topical
1.3
12.6
1335
10854
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.2
12.6
1799
15121
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.3
12.5
1242
10015
AA1AD
NOMESCO Finland
CT of head and brain
1.2
12.5
2225
19110
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
1.3
12.5
764
5756
2502
FHL
Thyroid exploration and possible biopsy
20.0
12.4
18
9
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.2
12.4
1918
16255
1930A
ICD-9 Finland
Malignant neoplasm of thyroid gland[CARCINOMA PAPILLARE THYREOIDEAE]
4.7
12.3
41
88
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.4
12.3
648
4761
XA402
NOMESCO Finland
ENMG
1.7
12.2
226
1304
N06AX21
ATC
duloxetine; oral
1.3
12.2
985
7731
A01
ICPC
Pain general/multiple sites
1.4
12.2
727
5457
L17
ICPC
Foot/toe symptom/complaint
1.2
12.2
2474
21506
S29
ICPC
Skin symptom/complaint other
1.2
12.1
1559
12953
E07
ICD-10 Finland
Other disorders of thyroid
15.9
12.1
19
12
M53.1
ICD-10 Finland
Cervicobrachial syndrome
1.3
12.1
963
7545
R20.2
ICD-10 Finland
Paraesthesia of skin
1.4
12.1
552
3957
D35.1
ICD-10 Finland
Benign neoplasm: Parathyroid gland
3.9
12.1
48
123
WZA90
NOMESCO Finland
Other doctors statement
1.2
12.0
2028
17323
UDQ02
NOMESCO Finland
Direct laryngoscopy
2.7
12.0
80
297
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
1.5
11.9
370
2450
C09DA01
ATC
losartan and diuretics; oral
1.3
11.9
967
7598
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.3
11.9
963
7560
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.2
11.9
2545
22216
J31.0
ICD-10 Finland
Chronic rhinitis
1.4
11.8
650
4812
Z01.2
ICD-10 Finland
Dental examination
1.2
11.8
3849
34764
R03AC03
ATC
terbutaline; inhalant
1.2
11.7
1327
10870
K11.2
ICD-10 Finland
Sialoadenitis
1.6
11.7
271
1672
D17.1
ICD-10 Finland
Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
1.6
11.7
274
1694
R12
ICD-10 Finland
Heartburn
1.4
11.6
628
4637
M01AH02
ATC
rofecoxib; oral
1.2
11.6
1339
10991
G04CB01
ATC
finasteride; oral (testosterone-5-alpha reductase inhibitors)
1.5
11.5
439
3040
SPAT1312
SPAT
General health counselling
1.2
11.5
3039
26986
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.3
11.5
1227
9980
R06AE07
ATC
cetirizine; oral
1.1
11.5
4414
40330
M19.0
ICD-10 Finland
Primary arthrosis of other joints
1.3
11.4
883
6887
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.1
11.4
5432
50373
Z3226
NOMESCO Finland
Physiotherapist
1.2
11.4
1728
14604
I83.9
ICD-10 Finland
Varicose veins of lower extremities without ulcer or inflammation
1.3
11.3
1063
8510
M79.7
ICD-10 Finland
Fibromyalgia
1.6
11.3
317
2053
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
1.3
11.3
996
7914
205
Kela drug reimbursment
Chronic hypertension
1.2
11.3
2632
23134
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.2
11.3
1452
12064
SPAT1058
SPAT
PEF monitoring instruction
1.3
11.2
777
5968
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
1.2
11.1
1366
11283
I49.4
ICD-10 Finland
Other and unspecified premature depolarization
1.6
11.1
310
2002
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
1.6
11.1
319
2075
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.2
11.1
1269
10400
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.3
11.1
1214
9902
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
1.5
11.1
334
2200
H43.8
ICD-10 Finland
Other disorders of vitreous body
1.3
11.1
859
6709
SAA02
NOMESCO Finland
Basic examination of mouth
1.1
11.0
6201
58096
E05
ICD-10 Finland
Thyrotoxicosis [hyperthyroidism]
2.3
11.0
94
402
L82
ICD-10 Finland
Seborrhoeic keratosis
1.2
10.9
1515
12682
A98
ICPC
Health maint/preventive medicine
1.3
10.9
10926
106995
R5140
NOMESCO Finland
Monitoring the use of the aid
1.3
10.9
779
6014
R31
ICD-10 Finland
Unspecified haematuria
1.3
10.8
654
4922
UJF30
NOMESCO Finland
Ileoscopy through colon
1.3
10.8
837
6531
D01
ICPC
Abdominal pain/cramps general
1.3
10.8
898
7075
H93.1
ICD-10 Finland
Tinnitus
1.4
10.8
547
4000
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.3
10.7
1101
8911
L16
ICPC
Ankle symptom/complaint
1.3
10.7
873
6861
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.2
10.7
2917
25946
R04.2
ICD-10 Finland
Haemoptysis
1.7
10.7
234
1422
E03.2
ICD-10 Finland
Hypothyroidism due to medicaments and other exogenous substances
3.1
10.7
56
180
M79.1
ICD-10 Finland
Myalgia
1.3
10.7
1148
9343
M79.0
ICD-10 Finland
Rheumatism, unspecified
1.5
10.7
374
2546
M17
ICD-10 Finland
Gonarthrosis [arthrosis of knee]
1.3
10.7
1039
8359
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.2
10.6
2926
26042
TPH04
NOMESCO Finland
Cathetrisation of vein
1.2
10.6
1819
15547
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.1
10.6
4998
46227
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
1.4
10.6
521
3791
21899
ICD-8 Finland
Uterine fibroma
1.4
10.6
529
3858
R96
ICPC
Asthma
1.3
10.6
805
6271
D21
ICPC
Swallowing problem
2.1
10.5
118
572
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
1.4
10.5
438
3089
R60.0
ICD-10 Finland
Localized oedema
1.3
10.5
1028
8277
Z01.7
ICD-10 Finland
Laboratory examination
1.3
10.5
968
7737
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.3
10.5
705
5395
R05
ICPC
Cough
1.2
10.4
2115
18352
D17.2
ICD-10 Finland
Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
1.8
10.4
182
1032
UDC00
NOMESCO Finland
Ear microscopy
1.4
10.4
594
4429
R01AD05
ATC
budesonide; nasal
1.3
10.4
693
5294
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
1.3
10.3
713
5475
R07.3
ICD-10 Finland
Other chest pain
1.3
10.3
829
6505
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
1.4
10.3
417
2925
A03FA02
ATC
cisapride; oral, rectal
1.3
10.3
763
5919
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.2
10.2
1995
17249
UJC01
NOMESCO Finland
Scopy of lower throat
2.4
10.2
84
354
K59.09
ICD-10 Finland
Constipation, unspecified
1.4
10.2
510
3723
H81.1
ICD-10 Finland
Benign paroxysmal vertigo
1.3
10.2
946
7565
SPAT1097
SPAT
Recording of ECG
1.2
10.1
1386
11584
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
1.9
10.1
142
750
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.3
10.1
942
7538
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.4
10.1
524
3848
R03BA02
ATC
budesonide; inhalant
1.2
10.0
1636
13913
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.2
10.0
2493
21999
C10AA07
ATC
rosuvastatin; oral
1.2
10.0
2263
19811
G04CA02
ATC
tamsulosin; oral
1.3
10.0
990
7979
C08CA13
ATC
lercanidipine; oral
1.2
10.0
1249
10342
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.2
9.9
1604
13629
J01DA06
ATC
[U] cefuroxime; systemic
1.2
9.9
1334
11132
D41.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Kidney
1.7
9.9
202
1207
E06
ICD-10 Finland
Thyroiditis
7.6
9.9
22
29
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.2
9.8
1753
15036
R49.03
ICD-10 Finland
Atrophic dysphonia
2.2
9.8
98
454
8290/3-C73.9
ICD-O-3
Oxyphilic adenocarcinoma of thyroid gland
20.0
9.8
14
7
H60.3
ICD-10 Finland
Other infective otitis externa
1.8
9.8
169
960
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
1.2
9.8
1106
9057
H01
ICPC
Ear pain/earache
1.3
9.8
872
6937
H53.1
ICD-10 Finland
Subjective visual disturbances
1.4
9.7
539
4002
R52.2
ICD-10 Finland
Other chronic pain
1.5
9.7
280
1827
C09CA06
ATC
candesartan; oral
1.2
9.7
2028
17637
19399
ICD-8 Finland
Malignant neoplasm of thyroid gland
5.1
9.6
29
57
J38.3
ICD-10 Finland
Other diseases of vocal cords
2.3
9.6
86
378
A60
ICPC
General and Unspecified, Result test/procedure
1.4
9.6
374
2607
M53.0
ICD-10 Finland
Cervicocranial syndrome
1.3
9.6
733
5712
DQE20
NOMESCO Finland
Implantation of foreign material in vocal chord
11.3
9.5
17
15
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.3
9.5
1022
8316
XX1AT
NOMESCO Finland
Other puncture with ultrasound guidance
2.1
9.5
98
461
R29
ICPC
Respiratory symptom/complaint other
1.4
9.4
504
3718
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.2
9.4
1075
8805
E83.50
ICD-10 Finland
Hypercalcemia
1.9
9.4
122
629
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.2
9.3
2504
22210
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
1.5
9.3
350
2420
A77
ICPC
Viral disease other/NOS
1.6
9.3
230
1449
E66.8
ICD-10 Finland
Other obesity
1.4
9.3
402
2857
R49.09
ICD-10 Finland
Unspecified dysphonia
2.1
9.3
103
497
GD1AD
NOMESCO Finland
Thorax CT examination
1.5
9.2
330
2262
D11.0
ICD-10 Finland
Benign neoplasm: Parotid gland
1.8
9.2
143
783
207
Kela drug reimbursment
Chronic arrhythmias
1.2
9.2
1238
10325
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
1.4
9.2
417
2993
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
1.3
9.1
632
4858
BBA40
NOMESCO Finland
Subtotal parathyroidectomy
2.8
9.1
55
196
R51.81
ICD-10 Finland
Facial pain NOS
1.7
9.1
196
1188
BBA70
NOMESCO Finland
Implantation or transplantation of parathyroid gland
6.7
9.1
22
33
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.3
9.1
689
5365
L13
ICPC
Hip symptom/complaint
1.2
9.1
1608
13773
J35.0
ICD-10 Finland
Chronic tonsillitis
1.5
9.1
325
2229
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.3
9.1
634
4881
SPAT1336
SPAT
Request for examination
1.5
9.0
320
2190
H60.9
ICD-10 Finland
Otitis externa, unspecified
1.4
9.0
487
3604
K07.60
ICD-10 Finland
Snapping jaw
1.4
9.0
394
2808
24210
ICD-8 Finland
Thyrotoxicosis with or without goitre, Toxic nodular goitre
3.2
9.0
44
136
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
1.3
9.0
716
5612
E03.80
ICD-10 Finland
Hypothyroidism caused by autoimmune thyroiditis
1.7
9.0
171
1004
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.3
9.0
688
5369
BBA20
NOMESCO Finland
Exploration of parathyroid gland
3.2
8.9
45
142
B01AA03
ATC
warfarin; systemic
1.2
8.9
1640
14093
M01AG02
ATC
tolfenamic acid; oral, rectal
1.2
8.9
1499
12781
J01FA15
ATC
telithromycin; oral
1.3
8.8
870
7006
H57.1
ICD-10 Finland
Ocular pain
1.5
8.8
256
1674
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.2
8.8
1429
12135
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.2
8.8
1458
12413
C03CA01
ATC
furosemide; systemic
1.2
8.8
2683
24013
N05BA04
ATC
oxazepam; oral
1.2
8.8
2376
21080
J38.4
ICD-10 Finland
Oedema of larynx
2.7
8.7
57
213
T78.4
ICD-10 Finland
Allergy, unspecified
1.4
8.6
361
2553
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
1.5
8.6
251
1645
D44.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Adrenal gland
2.1
8.6
96
467
M48.0
ICD-10 Finland
Spinal stenosis
1.2
8.6
1124
9348
N30.0
ICD-10 Finland
Acute cystitis
1.2
8.6
1433
12206
N63
ICD-10 Finland
Unspecified lump in breast
1.3
8.6
596
4586
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
1.4
8.6
476
3540
R06AX27
ATC
desloratadine; oral
1.2
8.5
2425
21581
D06
ICPC
Abdominal pain localized other
1.3
8.5
688
5408
2260A
ICD-9 Finland
Benign neoplasm of thyroid gland[NEOPLASMA BENIGNUM GLANDULAE THYREOIDEAE]
3.8
8.5
34
90
N06AA09
ATC
amitriptyline; systemic
1.2
8.5
984
8080
A07AA02
ATC
nystatin; oral
1.3
8.5
598
4613
D13.1
ICD-10 Finland
Benign neoplasm: Stomach
1.6
8.5
208
1311
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.2
8.4
1364
11581
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.3
8.4
836
6738
S82
ICPC
Naevus/mole
1.2
8.4
1073
8899
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
1.3
8.4
683
5367
R59.1
ICD-10 Finland
Generalized enlarged lymph nodes
2.0
8.4
104
528
D32.02
ICD-10 Finland
Benign tumor of the meninges at the base of the brain
2.1
8.4
88
418
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
1.7
8.4
158
923
M47.9
ICD-10 Finland
Spondylosis, unspecified
1.5
8.4
272
1829
A01AB04
ATC
amphotericin B; local oral
1.4
8.4
465
3460
SFA40
NOMESCO Finland
Replacement of krone of tooth
1.2
8.4
1849
16141
F51.0
ICD-10 Finland
Nonorganic insomnia
1.2
8.3
1044
8643
R03BA01
ATC
beclometasone; inhalant
1.2
8.3
1304
11036
24000
ICD-8 Finland
Simple goitre, Endemic
+∞
8.3
8
*
BA4KT
NOMESCO Finland
Sclerotherapy of thyroid
+∞
8.3
8
*
BB1BQ
NOMESCO Finland
Extensive scintigraphy of parathyroid gland, 2 isotopes, SPECT and low-dose CT
3.2
8.3
41
128
R03AK07
ATC
formoterol and budesonide; inhalant
1.2
8.3
1659
14355
A04
ICPC
Weakness/tiredness general
1.2
8.3
1114
9285
D12.4
ICD-10 Finland
Benign neoplasm: Descending colon
1.8
8.3
126
690
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.2
8.3
1334
11323
SDA01
NOMESCO Finland
Simple parodonthologic therapy
1.2
8.3
2217
19641
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
1.3
8.3
490
3681
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.3
8.3
601
4652
UGC12
NOMESCO Finland
Flexible bronchoscopy
1.3
8.3
578
4451
S54
ICPC
Skin, Repair/fix-suture/cast/prosth device
1.5
8.3
248
1637
C739
ICD-10 Finland
NA
5.8
8.3
22
38
R01AD01
ATC
beclometasone; nasal
1.2
8.2
1388
11829
D35.0
ICD-10 Finland
Benign neoplasm: Adrenal gland
1.8
8.2
135
759
J46
ICD-10 Finland
Status asthmaticus
1.5
8.2
243
1602
L02
ICPC
Back symptom/complaint
1.3
8.2
755
6036
RP210
NOMESCO Finland
NA
4.2
8.2
29
69
R49.0
ICD-10 Finland
Dysphonia
1.8
8.2
143
817
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
1.3
8.1
484
3639
M54.2
ICD-10 Finland
Cervicalgia
1.3
8.1
583
4505
M15.0
ICD-10 Finland
Primary generalized (osteo)arthrosis
1.5
8.1
299
2066
S21
ICPC
Skin texture symptom/complaint
1.2
8.1
1081
9014
M01AX05
ATC
glucosamine; oral
1.2
8.0
2238
19880
J45.1
ICD-10 Finland
Nonallergic asthma
1.3
8.0
593
4602
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
1.3
8.0
465
3484
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.2
8.0
846
6868
SPAT1310
SPAT
Counselling related to known health issue
1.1
8.0
3025
27450
Z50.1
ICD-10 Finland
Other physical therapy
1.3
8.0
484
3653
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.1
8.0
2569
23059
UJD02
NOMESCO Finland
Gastroscopy
1.4
8.0
390
2839
M77.0
ICD-10 Finland
Medial epicondylitis
1.6
8.0
173
1056
N64.4
ICD-10 Finland
Mastodynia
1.5
8.0
226
1474
K21
ICD-10 Finland
Gastro-oesophageal reflux disease
1.4
7.9
402
2944
SPAT1212
SPAT
Extensive examination of musculoskeletal system
1.3
7.9
694
5511
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
1.3
7.9
760
6102
F29
ICPC
Eye symptom/complaint other
1.3
7.9
693
5506
UJC02
NOMESCO Finland
Rigid oesophagoscopy
2.3
7.8
68
297
Z00.0
ICD-10 Finland
General medical examination
1.2
7.8
1590
13775
45499
ICD-8 Finland
Varicose veins of lower extremities, Other and unspecified, without ulcer
1.3
7.8
721
5763
E20
ICD-10 Finland
Hypoparathyroidism
10.8
7.8
14
13
24599
ICD-8 Finland
Thyroiditis, Unspecified
4.6
7.8
25
54
JN5SN
NOMESCO Finland
NA
9.4
7.8
15
16
N01
ICPC
Headache
1.3
7.7
730
5855
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.2
7.6
1942
17129
R23
ICPC
Voice symptom/complaint
1.6
7.6
175
1086
R03BA08
ATC
ciclesonide; inhalant
1.3
7.6
706
5646
C01BC04
ATC
flecainide; systemic
1.5
7.6
276
1903
J39.2
ICD-10 Finland
Other diseases of pharynx
2.1
7.6
79
374
A11
ICPC
Chest pain NOS
1.3
7.6
634
5005
JHB30
NOMESCO Finland
Rubber band ligature of haemorrhoids or prolapse of mucosa
1.3
7.6
480
3646
X59
ICD-10 Finland
Exposure to unspecified factor
1.2
7.6
1477
12749
C07AA07
ATC
sotalol; systemic
1.4
7.6
287
1994
J45
ICD-10 Finland
Asthma
1.2
7.6
865
7091
SAA03
NOMESCO Finland
Extended examination of mouth
1.1
7.5
3389
31067
R51
ICD-10 Finland
Headache
1.4
7.5
389
2860
N92.0
ICD-10 Finland
Excessive and frequent menstruation with regular cycle
1.3
7.5
734
5915
DFF00
NOMESCO Finland
Pure tone audiometry
1.3
7.5
753
6087
SHA01
NOMESCO Finland
Correction of physiology of bite - simple therapy visit
1.2
7.5
847
6939
XCW99
NOMESCO Finland
Other investigative procedure of eye
1.2
7.4
976
8120
U07
ICPC
Urine symptom/complaint other
1.3
7.4
507
3894
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
1.3
7.4
632
5004
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
1.2
7.4
827
6763
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
1.4
7.4
390
2879
E22.0
ICD-10 Finland
Acromegaly and pituitary gigantism
5.0
7.4
22
44
6421
FHL
Appendicectomy
1.3
7.3
426
3194
KED22
NOMESCO Finland
Transurethral resection of prostate
1.5
7.3
216
1427
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
1.3
7.3
631
5004
SPAT1283
SPAT
Restricted health certificate
1.2
7.3
1123
9493
K02.1
ICD-10 Finland
Caries of dentine
1.1
7.3
5134
48259
L12
ICPC
Hand/finger symptom/complaint
1.2
7.3
1207
10269
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.2
7.3
1707
14962
J20
ICD-10 Finland
Acute bronchitis
1.2
7.3
826
6767
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.2
7.2
1222
10414
BA1AQ
NOMESCO Finland
Thyroid SPECT with low dose CT
15.7
7.2
11
7
R00.0
ICD-10 Finland
Tachycardia, unspecified
1.4
7.2
306
2176
SPAT1211
SPAT
Application of soft bandage
1.2
7.2
768
6246
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
1.4
7.2
350
2552
EP1AT
NOMESCO Finland
Punction of soft tissue of neck with ultrasound guidance
7.3
7.2
16
22
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
1.2
7.2
1000
8374
N39.4
ICD-10 Finland
Other specified urinary incontinence
1.2
7.1
876
7234
D48.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Neoplasm of uncertain or unknown behaviour, unspecified
1.7
7.1
143
857
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
1.2
7.1
942
7844
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.1
7.1
4103
38126
R09
ICPC
Sinus symptom/complaint
1.3
7.1
630
5014
2180A
ICD-9 Finland
Uterine leiomyoma, Submucous leiomyoma of uterus
1.3
7.1
652
5211
EP1DG
NOMESCO Finland
Very extensive examination of soft tissue of neck with high intesity magnet
2.3
7.1
58
248
C08CA02
ATC
felodipine; oral
1.2
7.1
795
6501
M47.82
ICD-10 Finland
Other spondylosis, cervical region
1.4
7.1
335
2429
H66.9
ICD-10 Finland
Otitis media, unspecified
1.4
7.1
354
2590
E05.89
ICD-10 Finland
Other thyrotoxicosis
3.4
7.1
32
95
G04CA01
ATC
alfuzosin; oral
1.3
7.1
439
3327
E03.4
ICD-10 Finland
Atrophy of thyroid (acquired)
12.0
7.1
12
10
B01AF02
ATC
apixaban; oral
1.2
7.0
813
6671
N39.3
ICD-10 Finland
Stress incontinence
1.2
7.0
795
6511
L72.1
ICD-10 Finland
Trichilemmal cyst
1.3
7.0
472
3619
K59.0
ICD-10 Finland
Constipation
1.3
7.0
454
3463
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.2
7.0
1503
13072
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.1
7.0
4182
38926
H13
ICPC
Plugged feeling ear
1.2
7.0
1537
13398
E21.2
ICD-10 Finland
Other hyperparathyroidism
2.6
7.0
49
191
M47.80
ICD-10 Finland
Other spondylosis, multiple sites in spine
1.5
7.0
246
1685
D18.0
ICD-10 Finland
Haemangioma, any site
1.6
6.9
172
1089
SPAT1224
SPAT
Implementation of speech therapy rehabilitation plan
1.8
6.9
104
570
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
0.7
6.9
180
2639
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
1.1
6.9
3506
32344
EMB10
NOMESCO Finland
Tonsillectomy
1.4
6.9
314
2264
C03DA01
ATC
spironolactone; oral
1.2
6.9
872
7231
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.2
6.8
1418
12300
WX002
NOMESCO Finland
Sedation and analgesia
1.2
6.8
1837
16262
C10AA05
ATC
atorvastatin; oral
1.1
6.8
3539
32676
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
1.3
6.8
652
5239
A02BA04
ATC
nizatidine; systemic
1.3
6.8
691
5591
NGD05
NOMESCO Finland
Partial excision of meniscus of knee, arthroscopic
1.2
6.8
933
7797
G25.0
ICD-10 Finland
Essential tremor
1.5
6.8
188
1222
SPAT1301
SPAT
No procedures
1.1
6.8
3038
27808
E01.1
ICD-10 Finland
Iodine-deficiency-related multinodular (endemic) goitre
40.0
6.8
8
*
G50.1
ICD-10 Finland
Atypical facial pain
1.6
6.7
151
934
K08.80
ICD-10 Finland
Toothache NOS
1.3
6.7
594
4724
M50.3
ICD-10 Finland
Other cervical disc degeneration
1.5
6.7
189
1235
R06.4
ICD-10 Finland
Hyperventilation
1.7
6.7
123
719
R60.9
ICD-10 Finland
Oedema, unspecified
1.3
6.7
399
3005
A06AD11
ATC
lactulose; oral
1.2
6.7
1226
10525
E05.4
ICD-10 Finland
Thyrotoxicosis factitia
4.3
6.7
23
54
R35
ICD-10 Finland
Polyuria
1.3
6.7
425
3236
R11
ICD-10 Finland
Nausea and vomiting
1.3
6.7
663
5350
RL210
NOMESCO Finland
NA
2.5
6.7
48
192
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.1
6.7
2251
20241
J01
ICD-10 Finland
Acute sinusitis
1.3
6.6
381
2856
T90
ICPC
Diabetes non-insulin dependent
1.1
6.6
1953
17396
J34.2
ICD-10 Finland
Deviated nasal septum
1.4
6.6
293
2102
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.1
6.6
4070
37913
N04BC05
ATC
pramipexole; oral
1.3
6.6
658
5312
C73.94
ICD-10 Finland
Medullary thyroid carcinoma (thyroid)
7.8
6.6
14
18
Z2221
NOMESCO Finland
Medical doctor
1.1
6.6
2570
23319
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.2
6.6
1178
10095
SPAT1260
SPAT
Consultation of another employee
1.2
6.5
1625
14299
K78
ICPC
Atrial fibrillation/flutter
1.3
6.5
599
4790
R06AE09
ATC
levocetirizine; oral
1.2
6.5
1228
10566
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.3
6.5
610
4892
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
1.4
6.5
289
2078
S01
ICPC
Pain/tenderness of skin
1.4
6.5
330
2428
24400
ICD-8 Finland
Myxoedema, (hypothyreosis) post therapiam
5.3
6.4
18
34
N17
ICPC
Vertigo/dizziness
1.2
6.4
1024
8682
UDQ22
NOMESCO Finland
Microlaryngoscopy
2.3
6.4
56
248
TPH07
NOMESCO Finland
Cathetrisation of artery
1.2
6.4
798
6604
D25.0
ICD-10 Finland
Submucous leiomyoma of uterus
1.4
6.4
344
2552
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
1.4
6.4
358
2672
K85
ICPC
Elevated blood pressure
1.2
6.4
1420
12392
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.1
6.4
3668
34036
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
1.2
6.3
1576
13868
D44.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Endocrine gland, unspecified
6.5
6.3
15
23
R4110
NOMESCO Finland
Physiotherapy
1.1
6.3
2444
22164
N41.1
ICD-10 Finland
Chronic prostatitis
2.0
6.3
76
385
24191
ICD-8 Finland
NA
+∞
6.2
6
*
E042, D440
ICD-10 Finland
NA
+∞
6.2
6
*
J30.0
ICD-10 Finland
Vasomotor rhinitis
1.5
6.2
197
1324
BWA00
NOMESCO Finland
Repair of wound dehiscence in endocrine surgery
26.7
6.2
8
*
H92.0
ICD-10 Finland
Otalgia
1.3
6.2
395
3009
I71.2
ICD-10 Finland
Thoracic aortic aneurysm, without mention of rupture
1.6
6.2
150
945
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
1.4
6.2
337
2507
L03.0
ICD-10 Finland
Cellulitis of finger and toe
1.3
6.2
524
4149
ZXD20
NOMESCO Finland
Day surgery
1.2
6.2
1147
9858
SDA02
NOMESCO Finland
Parodonthologic therapy
1.1
6.2
2959
27168
K43
ICPC
Cardiovascular, Other diagnostic procedure
1.8
6.1
96
536
D12.0
ICD-10 Finland
Benign neoplasm: Caecum
1.5
6.1
185
1229
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
1.5
6.1
209
1429
L02.2
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of trunk
1.4
6.1
273
1965
H02AB04
ATC
methylprednisolone; systemic
1.2
6.1
1345
11722
M01AB55
ATC
diclofenac, combinations; oral
1.2
6.1
648
5275
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.2
6.1
885
7440
N06AX16
ATC
venlafaxine; oral
1.2
6.1
1111
9536
R04
ICPC
Breathing problem other
1.4
6.1
247
1748
E06.0
ICD-10 Finland
Acute thyroiditis
3.8
6.1
23
60
SPAT1047
SPAT
Ultrasound examination of thyroid
8.6
6.0
12
14
K86
ICPC
Hypertension uncomplicated
1.2
6.0
1054
9011
A08
ICPC
Swelling
1.3
6.0
358
2702
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.2
6.0
637
5180
M47.1
ICD-10 Finland
Other spondylosis with myelopathy
1.8
6.0
95
533
M01AC01
ATC
piroxicam; systemic, rectal
1.2
6.0
1223
10595
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.2
6.0
1067
9136
L91.0
ICD-10 Finland
Hypertrophic scar
1.8
6.0
96
537
Mortality – FinRegistry
↥Association
Association between endpoint E4_NONTOXIC_THYROID and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_NONTOXIC_THYROID | 0.99 [0.91, 1.07] | 0.797 |
| Birth year | 0.99 [0.98, 1.0] | 0.017 |
During the follow-up period (1.1.1998 — 31.12.2019), 5962 out of 44264 females with E4_NONTOXIC_THYROID died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_NONTOXIC_THYROID | 0.999 [0.91, 1.1] | 0.977 |
| Birth year | 0.984 [0.97, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 1762 out of 8829 males with E4_NONTOXIC_THYROID died.
Mortality risk
Mortality risk for people of age
years, who have E4_NONTOXIC_THYROID.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.085% | 0.134% |
| 5 | 0.517% | 0.972% |
| 10 | 1.226% | 2.72% |
| 15 | 2.424% | 5.03% |
| 20 | 4.227% | 8.358% |
Relationships between endpoints
↥Index endpoint: E4_NONTOXIC_THYROID – Nontoxic goitre/thyroid nodule
GWS hits: 68
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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