Vaginal neoplasm: Tumors or cancer of the VAGINA.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleonly females |
293373 |
2. Check conditionsNone |
293373 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
456 |
4. Check minimum number of eventsNone |
456 |
5. Include endpointsNone |
456 |
6. Filter based on genotype QC (FinnGen only) |
456 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D28
- Name in latin
- Neoplasma benignum vaginae
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Vagina
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm: Vagina
- Benign neoplasm of other and unspecified female genital organs
- Benign neoplasm of other and unspecified female genital organs
- Benign neoplasms
- Benign neoplasms
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 3069 | 3069 | - |
| Only index persons | 2824 | 2824 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.09 | 0.09 | - |
| Only index persons | 0.10 | 0.10 | - |
| Median age at first event (years) | |||
| Whole population | - | 42.47 | - |
| Only index persons | - | 41.39 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 456 | 456 | - |
| Unadjusted period prevalence (%) | 0.16 | 0.16 | - |
| Median age at first event (years) | 41.63 | 41.63 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 407
- Matched controls
- 4070
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D28.1
ICD-10 Finland
Benign neoplasm: Vagina
+∞
323.0
271
*
22110
ICD-8 Finland
Benign neoplasm of other female genital organs, Vagina
+∞
100.2
92
*
LEB10
NOMESCO Finland
Excision of lesion of vagina
166.8
89.2
91
7
2211A
ICD-9 Finland
Benign neoplasm of other female genital organs, Vagina
+∞
28.5
27
*
22111
ICD-8 Finland
NA
+∞
16.8
16
*
8412
FHL
Vaginal tumor removal
+∞
14.7
14
*
LEB20
NOMESCO Finland
Marsupialisation of vaginal cyst
+∞
14.7
14
*
LEB00
NOMESCO Finland
Biopsy of vagina
7.1
12.8
31
47
N89.8
ICD-10 Finland
Other specified noninflammatory disorders of vagina
20.6
9.9
14
7
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
2.7
9.5
66
268
JN2DG
NOMESCO Finland
Very extensive MRI examination of lower part of abdoment with high intensity magnet
13.4
7.9
13
10
N36.1
ICD-10 Finland
Urethral diverticulum
30.6
7.2
9
*
N89.9
ICD-10 Finland
Noninflammatory disorder of vagina, unspecified
20.4
7.2
10
5
LEB30
NOMESCO Finland
Destruction of lesion of vaginal mucosa
10.3
7.1
13
13
N84.2
ICD-10 Finland
Polyp of vagina
18.4
6.3
9
5
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_VULVA and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_VULVA | 0.972 [0.81, 1.17] | 0.766 |
| Birth year | 0.997 [0.99, 1.01] | 0.428 |
During the follow-up period (1.1.1998 — 31.12.2019), 141 out of 1498 females with CD2_BENIGN_VULVA died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_VULVA.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.098% | No data |
| 5 | 0.585% | No data |
| 10 | 1.502% | No data |
| 15 | 3.023% | No data |
| 20 | 5.108% | No data |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_VULVA – Benign neoplasm: Vagina
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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