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Degeneration of nervous system due to alcohol

ALCONEURODEGEN

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 G31.2
  • Cause of death: ICD-10 G31.2

2 out of 7 registries used, show all original rules.

778

4. Check minimum number of events

None

778

5. Include endpoints

None

778

6. Filter based on genotype QC (FinnGen only)

778

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
G31
Name in latin
Degeneratio systematis nervosi ex alcohol (aethylico)

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 778 127 651
Unadjusted period prevalence (%) 0.25 0.04 0.29
Median age at first event (years) 59.68 57.78 60.05

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
721
Matched controls
7207
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G31.2
ICD-10 Finland
Degeneration of nervous system due to alcohol
+∞
323.0
721
6
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
27.0
271.3
409
333
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
28.2
138.5
193
92
F10.20
ICD-10 Finland
Alcohol dependence currently independent
27.2
108.5
152
70
F10.25
ICD-10 Finland
Alcohol dependence continuous use
25.0
104.3
150
75
N07BB01
ATC
disulfiram; oral
13.5
92.0
169
160
P15
ICPC
Chronic alcohol abuse
16.3
90.6
152
116
F10.40
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without seizures
28.2
86.3
119
50
R56.8
ICD-10 Finland
Other and unspecified convulsions
11.8
85.3
167
179
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
4.7
79.4
380
1375
F10.9
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Unspecified mental and behavioural disorder
46.5
73.7
90
22
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
21.3
72.0
108
59
K70.3
ICD-10 Finland
Alcoholic cirrhosis of liver
22.8
67.5
99
50
F10.31
ICD-10 Finland
Withdrawal symptoms caused by alcohol with seizures
38.3
66.9
85
25
F10.26
ICD-10 Finland
Alcohol dependence periodic alcoholism
17.8
66.3
106
69
F10.24
ICD-10 Finland
Alcohol depence active use
23.2
63.3
92
45
F10.39
ICD-10 Finland
Withdrawal symptoms caused by alcohol UNS
22.1
62.9
93
48
N05AH04
ATC
quetiapine; oral
5.2
62.2
227
586
N05BA02
ATC
chlordiazepoxide; systemic
13.1
60.3
110
98
F10.21
ICD-10 Finland
Alcohol dependence currently abstinent, but staying in restrictive environment
35.2
58.7
76
24
F10.49
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without information about seizures
31.1
58.4
78
28
AA1AD
NOMESCO Finland
CT of head and brain
3.9
57.5
314
1185
G62.1
ICD-10 Finland
Alcoholic polyneuropathy
79.9
52.9
59
8
3039X
ICD-9 Finland
Alcohol dependence syndrome, Other and unspecified alcohol dependence
16.2
51.0
84
58
F10.2
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Dependence syndrome
21.0
49.5
74
39
F10.30
ICD-10 Finland
Withdrawal symptoms caused by alcohol uncomplicated
26.7
49.0
68
28
F10.09
ICD-10 Finland
Alcohol intoxication UNS
13.6
48.5
86
71
N05BA04
ATC
oxazepam; oral
3.8
48.1
256
913
N06AX11
ATC
mirtazapine; oral
3.4
47.2
319
1374
N06AB04
ATC
citalopram; systemic
3.8
46.8
242
840
P16
ICPC
Acute alcohol abuse
18.3
46.6
73
44
N05CD07
ATC
temazepam; oral
4.5
46.3
188
522
T36
ICD-10 Finland
Poisoning by systemic antibiotics
10.7
44.2
88
92
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.9
43.6
216
716
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
14.1
42.6
74
58
S01.0
ICD-10 Finland
Open wound of scalp
5.1
42.1
147
346
N05BA01
ATC
diazepam; systemic, rectal
4.1
40.3
180
540
C07AA05
ATC
propranolol; systemic
3.8
39.8
200
665
K70.1
ICD-10 Finland
Alcoholic hepatitis
25.8
39.4
55
23
N05CF01
ATC
zopiclone; oral
3.0
38.7
319
1521
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
8.5
37.9
86
113
J18.9
ICD-10 Finland
Pneumonia, unspecified
3.0
37.5
279
1237
A28
ICPC
Limited function/disability NOS
3.8
36.5
179
578
A06AD11
ATC
lactulose; oral
3.7
35.8
180
592
Z72.1
ICD-10 Finland
Alcohol use
16.6
35.4
57
37
F32.9
ICD-10 Finland
Depressive episode, unspecified
4.6
35.2
133
336
K92.0
ICD-10 Finland
Haematemesis
8.0
32.1
75
103
S06.0
ICD-10 Finland
Concussion
4.2
30.6
129
359
F05.9
ICD-10 Finland
Delirium, unspecified
9.9
30.3
62
68
R27.0
ICD-10 Finland
Ataxia, unspecified
86.4
30.0
33
*
W19
ICD-10 Finland
Unspecified fall
4.1
29.9
126
350
L28
ICPC
Limited function/disability (L)
3.2
28.6
171
631
R53
ICD-10 Finland
Malaise and fatigue
3.0
28.5
196
794
E87.6
ICD-10 Finland
Hypokalaemia
8.7
28.2
62
77
N05AD01
ATC
haloperidol; systemic
8.6
28.0
62
78
K86.00
ICD-10 Finland
Acute pancreatitis caused by alcohol
10.9
27.9
54
53
SPAT1309
SPAT
Guidance related to psychoactive substances / risk behaviour
7.7
27.2
65
92
N05AA02
ATC
levomepromazine; systemic
5.9
27.0
78
144
F10.73
ICD-10 Finland
Residual or late-onset psychosis caused by alcohol dementia
47.7
26.7
32
7
V03AA01
ATC
NA
8.5
26.5
59
75
G40.9
ICD-10 Finland
Epilepsy, unspecified
6.8
25.1
65
104
F10.03
ICD-10 Finland
Alcohol-related acute intoxication with delirium
28.7
24.7
33
12
S42.2
ICD-10 Finland
Fracture of upper end of humerus
6.4
24.4
66
112
K70.4
ICD-10 Finland
Alcoholic hepatic failure
16.6
23.9
38
24
G72.8
ICD-10 Finland
Other specified myopathies
10.4
23.4
46
47
N05AX08
ATC
risperidone; systemic
4.1
23.2
95
255
N05AB01
ATC
dixyrazine; systemic
9.9
22.9
46
49
K70.9
ICD-10 Finland
Alcoholic liver disease, unspecified
26.9
22.8
31
12
R41.0
ICD-10 Finland
Disorientation, unspecified
6.5
22.6
60
99
F10.41
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol with seizures
33.5
22.6
29
9
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
4.8
22.2
77
175
N05AD03
ATC
melperone; systemic
11.7
22.2
41
37
SPAT1265
SPAT
Breathalyser
11.1
22.1
42
40
E51.2
ICD-10 Finland
Wernicke encephalopathy
64.6
22.0
25
*
3050A
ICD-9 Finland
Nondependent abuse of drugs, Alcohol abuse
13.3
21.9
38
30
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.3
21.8
255
1368
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
4.2
21.8
86
223
F03
ICD-10 Finland
Unspecified dementia
5.8
21.5
63
118
F10.8
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Other mental and behavioural disorders
51.7
21.2
25
5
R26.0
ICD-10 Finland
Ataxic gait
38.4
20.9
26
7
N03AF01
ATC
carbamazepine; oral, rectal
4.3
20.8
81
207
C03CA01
ATC
furosemide; systemic
2.2
20.4
261
1452
N06AB03
ATC
fluoxetine; oral
3.1
20.0
118
424
N03AG01
ATC
valproic acid; systemic, rectal
4.4
19.9
75
186
N05AH03
ATC
olanzapine; systemic
4.9
19.9
67
148
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
4.9
19.8
66
144
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
3.3
19.1
102
340
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.7
18.8
144
609
F10
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol
39.5
18.6
23
6
A98
ICPC
Health maint/preventive medicine
0.4
18.4
508
6086
V03AB30
ATC
NA
14.0
18.4
31
23
S72.0
ICD-10 Finland
Fracture of neck of femur
5.3
18.3
57
115
K86.08
ICD-10 Finland
Alcohol-induced chronic pancreatitis
20.0
18.3
27
14
SPAT1216
SPAT
Assessment of functional ability
2.7
18.3
144
618
2910A
ICD-9 Finland
Alcoholic psychoses, Alcohol withdrawal delirium
53.9
18.0
21
*
S82.6
ICD-10 Finland
Fracture of lateral malleolus
4.1
17.8
71
186
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
4.7
17.7
61
138
SPAT1227
SPAT
Substance abuse rehabilitation
16.1
17.6
28
18
D64.9
ICD-10 Finland
Anaemia, unspecified
3.0
17.5
111
415
G40.51
ICD-10 Finland
Epileptic seizures related to alcohol
24.8
17.4
24
10
S22.3
ICD-10 Finland
Fracture of rib
3.3
17.1
89
291
K85
ICD-10 Finland
Acute pancreatitis
7.2
16.9
41
60
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
3.5
16.8
81
249
N06AB10
ATC
escitalopram; oral
2.5
16.8
146
661
F10.74
ICD-10 Finland
Residual or late-onset psychosis caused by alcohol otherwise permanently impaired intelligence
92.2
16.6
18
*
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
3.8
16.6
73
208
EBA15
NOMESCO Finland
Extraction of large number of teeth
4.1
16.6
66
172
N03AX14
ATC
levetiracetam; systemic
5.6
16.1
47
88
F10.23
ICD-10 Finland
Alcohol dependence currently abstinent but using aversion-inducing or inhibitory medication
21.5
16.1
23
11
F10.01
ICD-10 Finland
Alcohol-related acute intoxication with permanent or other somatic damage
16.1
15.8
25
16
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
6.7
15.4
39
61
K70.0
ICD-10 Finland
Alcoholic fatty liver
10.7
15.3
29
28
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
2.6
15.2
124
541
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.1
15.1
87
305
SPAT1254
SPAT
Administration of medicine
2.4
15.1
138
636
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
3.9
15.1
63
172
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.7
14.8
108
442
P20
ICPC
Memory disturbance
2.6
14.7
112
468
N06AX16
ATC
venlafaxine; oral
2.7
14.3
104
423
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
3.7
14.3
64
186
Z2446
NOMESCO Finland
Social worker
3.7
14.1
63
182
SPAT1307
SPAT
Psychosocial counselling and guidance
5.4
13.8
41
79
S01.1
ICD-10 Finland
Open wound of eyelid and periocular area
5.6
13.8
40
75
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.4
13.8
123
559
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.7
13.6
98
397
E87.2
ICD-10 Finland
Acidosis
18.7
13.4
20
11
SPAT1234
SPAT
Support of social functional capacity
3.6
13.3
60
175
F10.6
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Amnesic syndrome
40.9
13.2
16
*
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
5.6
13.2
38
71
OAB43
SPAT
NA
0.1
13.1
*
433
S82.8
ICD-10 Finland
Fractures of other parts of lower leg
4.6
13.1
45
102
ZXD05
NOMESCO Finland
Urgent procedure
1.9
13.0
243
1518
F10.4
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Withdrawal state with delirium
23.0
12.9
18
8
N05AF03
ATC
chlorprothixene; systemic
5.4
12.9
38
73
R18
ICD-10 Finland
Ascites
7.0
12.8
31
46
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.8
12.5
85
332
A04
ICPC
Weakness/tiredness general
2.7
12.5
93
381
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.1
12.3
156
834
F10.02
ICD-10 Finland
Alcohol-related acute intoxication with other acute clinical complications
38.2
12.2
15
*
C03DA01
ATC
spironolactone; oral
2.5
12.2
103
452
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
6.0
12.2
33
57
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.4
12.2
109
497
K29.2
ICD-10 Finland
Alcoholic gastritis
21.7
12.0
17
8
X59
ICD-10 Finland
Exposure to unspecified factor
2.1
12.0
158
859
F10.06
ICD-10 Finland
Alcohol-related acute intoxication with seizures
30.6
11.7
15
5
F10.59
ICD-10 Finland
Alcohol psychosis, mixed type
30.6
11.7
15
5
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.1
11.7
65
221
L89
ICD-10 Finland
Decubitus ulcer and pressure area
6.3
11.6
30
49
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
4.4
11.5
41
97
N06AX03
ATC
mianserin; oral
3.5
11.5
53
158
7803A
ICD-9 Finland
General symptoms, Convulsions
12.1
11.4
20
17
X44
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
8.5
11.4
24
29
XF400
NOMESCO Finland
ECG with 12 standard connections
2.1
11.3
149
809
R42
ICD-10 Finland
Dizziness and giddiness
2.0
11.2
159
886
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
3.0
11.2
65
230
N05BA06
ATC
lorazepam; systemic, sublingual
3.4
11.2
53
162
F10.3
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Withdrawal state
20.4
11.2
16
8
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.1
11.0
136
718
K92.1
ICD-10 Finland
Melaena
3.1
11.0
62
214
30300
ICD-8 Finland
Alcoholism, Episodic excessive drinking
7.1
10.9
26
38
R11
ICD-10 Finland
Nausea and vomiting
3.0
10.9
63
222
SPAT1247
SPAT
Outpatient detoxication and monitoring
12.2
10.9
19
16
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.4
10.9
100
460
SPAT1229
SPAT
Assessment of need for aid
2.7
10.9
75
296
G41.9
ICD-10 Finland
Status epilepticus, unspecified
10.8
10.8
20
19
N05BE01
ATC
buspirone; oral
4.2
10.8
40
99
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.9
10.8
192
1167
G31.0
ICD-10 Finland
Circumscribed brain atrophy
18.1
10.8
16
9
G31.9
ICD-10 Finland
Degenerative disease of nervous system, unspecified
21.8
10.7
15
7
N06AB06
ATC
sertraline; oral
2.5
10.6
83
352
G40
ICD-10 Finland
Epilepsy
10.2
10.6
20
20
S72.1
ICD-10 Finland
Pertrochanteric fracture
6.5
10.4
26
41
Z03
ICPC
Housing/neighbourhood problem
12.3
10.4
18
15
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.6
10.4
78
322
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
0.3
10.3
20
663
R26.8
ICD-10 Finland
Other and unspecified abnormalities of gait and mobility
5.2
10.3
31
62
N05BA12
ATC
alprazolam; oral
2.5
10.2
81
346
J01FA10
ATC
azithromycin; systemic
0.6
10.2
176
2616
NHJ10
NOMESCO Finland
Internal fixation of fracture of ankle using wire, rod, cerclage or pin
3.4
10.1
48
147
N06AA12
ATC
doxepin; systemic
3.3
10.1
51
164
W10
ICD-10 Finland
Fall on and from stairs and steps
3.2
10.0
51
165
SPAT1240
SPAT
Therapeutic discussion
2.7
9.9
67
262
2918A
ICD-9 Finland
Alcoholic psychoses, Other specified alcoholic psychosis
17.0
9.9
15
9
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
3.1
9.8
53
179
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
5.5
9.8
28
53
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
4.4
9.7
34
80
A02BC02
ATC
pantoprazole; systemic
1.7
9.7
447
3577
P29
ICPC
Psychological sympt/compl other
4.0
9.6
38
100
F29
ICD-10 Finland
Unspecified nonorganic psychosis
4.5
9.6
33
76
A09AA02
ATC
multienzymes (lipase, protease etc.)
4.8
9.6
31
67
T90.5
ICD-10 Finland
Sequelae of intracranial injury
6.5
9.6
24
38
E86
ICD-10 Finland
Volume depletion
4.4
9.5
33
77
M01AH05
ATC
etoricoxib; oral
0.6
9.5
219
3049
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
4.7
9.5
31
68
EBA00
NOMESCO Finland
Extraction of tooth
1.7
9.4
231
1542
S62.3
ICD-10 Finland
Fracture of other metacarpal bone
4.5
9.4
32
73
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
2.7
9.4
63
244
G93.4
ICD-10 Finland
Encephalopathy, unspecified
17.8
9.4
14
8
TKC20
NOMESCO Finland
Catheterisation of bladder
2.5
9.3
75
323
N03AF02
ATC
oxcarbazepine; oral
4.2
9.3
34
84
T74.1
ICD-10 Finland
Physical abuse
6.4
9.1
23
37
R55
ICD-10 Finland
Syncope and collapse
2.2
9.1
96
471
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.6
9.1
67
274
309
Kela drug reimbursment
Nalmefene and naltrexone
15.8
9.1
14
9
S43.0
ICD-10 Finland
Dislocation of shoulder joint
3.4
9.0
43
133
RS230
NOMESCO Finland
NA
24.3
8.9
12
5
G47.3
ICD-10 Finland
Sleep apnoea
0.5
8.8
66
1258
Z08
ICPC
Social welfare problem
7.3
8.8
20
28
SPAT1053
SPAT
Memory test
2.0
8.8
116
627
NFJ52
NOMESCO Finland
Internal fixation of fracture of upper femur with screws and sideplate
14.2
8.7
14
10
F02.89*G40.9
ICD-10 Finland
Dementia in epilepsy
50.6
8.7
10
*
G11.9
ICD-10 Finland
Hereditary ataxia, unspecified
50.6
8.7
10
*
W00
ICD-10 Finland
Fall on same level involving ice and snow
2.2
8.6
88
426
30310
ICD-8 Finland
Alcoholism, Habitual excessive drinking
7.1
8.6
20
29
Z02.7
ICD-10 Finland
Issue of medical certificate
2.8
8.6
54
202
F17.29
ICD-10 Finland
Addiction caused by tobacco UNS
5.0
8.6
26
53
A29
ICPC
General symptom/complaint other
2.2
8.6
86
414
NGJ60
NOMESCO Finland
Internal fixation of fracture of knee or lower leg using intramedullary nail, other or unspecified
9.1
8.6
17
19
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
2.9
8.6
51
185
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.2
8.5
90
442
S06.3
ICD-10 Finland
Focal brain injury
5.2
8.5
25
49
T51.0
ICD-10 Finland
Toxic effect: Ethanol
27.9
8.5
11
*
I85.9
ICD-10 Finland
Oesophageal varices without bleeding
7.5
8.5
19
26
S22.4
ICD-10 Finland
Multiple fractures of ribs
4.2
8.5
31
77
Z02.4
ICD-10 Finland
Examination for driving licence
0.5
8.4
81
1431
Y90.8
ICD-10 Finland
Blood alcohol level of 240 mg/100 ml or more
91.0
8.4
9
*
N17.9
ICD-10 Finland
Acute renal failure, unspecified
3.0
8.4
46
158
N03AB02
ATC
phenytoin; systemic
6.8
8.4
20
30
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
5.1
8.4
25
50
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.7
8.4
57
224
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.1
8.3
91
455
F60.9
ICD-10 Finland
Personality disorder, unspecified
9.6
8.3
16
17
N06AB05
ATC
paroxetine; oral
2.9
8.3
50
183
S01
ICD-10 Finland
Open wound of head
6.6
8.2
20
31
K75.9
ICD-10 Finland
Inflammatory liver disease, unspecified
7.7
8.2
18
24
IAB10
NOMESCO Finland
Psychiatric consultation concerning substance abuse
33.7
8.1
10
*
N07BB04
ATC
naltrexone; oral
33.7
8.1
10
*
3018X
ICD-9 Finland
Personality disorders, Other personality disorders[MUU TAI SEKAMUOTOINEN PERSOONALLISUUSHÄIRIÖ]
9.1
8.1
16
18
B18.2
ICD-10 Finland
Chronic viral hepatitis C
9.1
8.1
16
18
L76
ICPC
Fracture: other
4.7
8.1
26
57
F05.8
ICD-10 Finland
Other delirium
10.2
8.1
15
15
F10.0
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Acute intoxication
6.0
8.0
21
36
NFJ50
NOMESCO Finland
Internal fixation of fracture of neck of femur with nail or screw
13.2
7.9
13
10
TAB00
NOMESCO Finland
Lumbar puncture
3.2
7.9
40
131
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
2.3
7.9
71
324
R01AD09
ATC
mometasone; nasal
0.6
7.8
126
1937
R25.1
ICD-10 Finland
Tremor, unspecified
4.0
7.8
30
78
K05.31
ICD-10 Finland
Periodontitis pronounced
2.1
7.8
87
439
N28
ICPC
Limited function/disability (N)
5.1
7.8
23
46
30320
ICD-8 Finland
Alcoholism, Alcoholic addiction
6.5
7.7
19
30
G37.2
ICD-10 Finland
Central pontine myelinolysis
45.5
7.7
9
*
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
2.1
7.7
82
406
R33
ICD-10 Finland
Retention of urine
2.1
7.6
88
449
S42.0
ICD-10 Finland
Fracture of clavicle
3.4
7.6
35
106
P99
ICPC
Psychological disorders other
5.0
7.6
23
47
N03AE01
ATC
clonazepam; systemic
2.8
7.6
46
169
F10.52
ICD-10 Finland
Psychotic alcohol hallucination
25.3
7.6
10
*
NBJ62
NOMESCO Finland
Internal fixation of fracture of shoulder or upper arm using plate and screws, humerus
5.8
7.6
20
35
K86.3
ICD-10 Finland
Pseudocyst of pancreas
10.2
7.6
14
14
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
3.5
7.5
33
97
EBA30
NOMESCO Finland
Excision of root of tooth
2.6
7.5
55
226
L57.0
ICD-10 Finland
Actinic keratosis
0.2
7.5
10
406
N06AA09
ATC
amitriptyline; systemic
2.3
7.5
71
333
K08.3
ICD-10 Finland
Retained dental root
2.3
7.3
65
293
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
11.0
7.3
13
12
K86.9
ICD-10 Finland
Disease of pancreas, unspecified
11.0
7.3
13
12
S01.8
ICD-10 Finland
Open wound of other parts of head
5.2
7.3
21
41
TPH04
NOMESCO Finland
Cathetrisation of vein
1.7
7.3
155
983
E13.7
ICD-10 Finland
Other specified diabetes mellitus, with multiple complications
15.9
7.2
11
7
N02AA05
ATC
oxycodone; systemic
1.9
7.2
113
647
Z53.2
ICD-10 Finland
Procedure not carried out because of patient's decision for other and unspecified reasons
7.4
7.2
16
22
9800A
ICD-9 Finland
Toxic effect of alcohol, Ethyl alcohol
30.3
7.2
9
*
E970A
ICD-9 Finland
Injury due to legal intervention by firearms
30.3
7.2
9
*
2913A
ICD-9 Finland
Alcoholic psychoses, Alcohol withdrawal hallucinosis
30.3
7.2
9
*
G25.2
ICD-10 Finland
Other specified forms of tremor
20.2
7.1
10
5
K74.6
ICD-10 Finland
Other and unspecified cirrhosis of liver
5.4
7.1
20
38
NA1AD
NOMESCO Finland
Cervical spine CT examination
3.0
7.0
40
140
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
3.8
7.0
28
76
S00.0
ICD-10 Finland
Superficial injury of scalp
4.5
7.0
23
52
S32.0
ICD-10 Finland
Fracture of lumbar vertebra
3.5
7.0
31
92
NFB20
NOMESCO Finland
Primary partial prosthetic replacement of hip joint using cement, other or unspecified
4.3
7.0
24
57
S92.3
ICD-10 Finland
Fracture of metatarsal bone
3.6
6.9
29
82
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
2.6
6.9
49
198
G25.0
ICD-10 Finland
Essential tremor
4.1
6.9
25
62
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.5
6.9
52
219
E16.2
ICD-10 Finland
Hypoglycaemia, unspecified
5.1
6.8
20
40
OAB48
SPAT
NA
0.0
6.8
*
201
S82.2
ICD-10 Finland
Fracture of shaft of tibia
5.4
6.8
19
36
S82.0
ICD-10 Finland
Fracture of patella
5.4
6.8
19
36
R01AD12
ATC
fluticasone furoate; nasal
0.5
6.8
58
1068
RS110
NOMESCO Finland
NA
40.4
6.8
8
*
XA800
NOMESCO Finland
Neuropsychological investigation
2.9
6.7
39
140
X45
ICD-10 Finland
Accidental poisoning by and exposure to alcohol
22.7
6.7
9
*
C10AA07
ATC
rosuvastatin; oral
0.5
6.7
72
1236
SPAT1241
SPAT
Extensive assessment of psychosocial situation
7.9
6.6
14
18
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.0
6.6
36
125
N02AX02
ATC
tramadol; systemic, rectal
1.5
6.6
311
2408
K86.01
ICD-10 Finland
Late effects of pancreatitis caused by alcohol
12.4
6.6
11
9
Z76.8
ICD-10 Finland
Persons encountering health services in other specified circumstances
3.5
6.6
29
86
ZXD35
NOMESCO Finland
Usual procedure
3.2
6.6
33
108
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
2.0
6.5
88
479
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.9
6.5
99
564
S42.3
ICD-10 Finland
Fracture of shaft of humerus
6.3
6.5
16
26
R40.2
ICD-10 Finland
Coma, unspecified
5.8
6.5
17
30
F10.51
ICD-10 Finland
Psychotic alcohol paranoia
70.4
6.4
7
*
S21.1
ICD-10 Finland
Open wound of front wall of thorax
70.4
6.4
7
*
RS223
NOMESCO Finland
NA
70.4
6.4
7
*
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
2.6
6.4
45
181
T50.9
ICD-10 Finland
Poisoning: Other and unspecified drugs, medicaments and biological substances
14.5
6.4
10
7
SPAT1274
SPAT
Brief intervention in person with addiction symptoms
14.5
6.4
10
7
D07AA02
ATC
hydrocortisone; topical
2.0
6.4
83
445
Z29
ICPC
Social problem NOS
5.0
6.4
19
39
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.8
6.4
121
741
Z09.4
ICD-10 Finland
Follow-up examination after treatment of fracture
2.8
6.4
38
140
A41.9
ICD-10 Finland
Sepsis, unspecified
3.0
6.3
34
117
C10AX09
ATC
ezetimibe; oral
0.4
6.3
20
532
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.9
6.3
97
552
F19.1
ICD-10 Finland
Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances, harmful use
18.2
6.3
9
5
Z72.8
ICD-10 Finland
Other problems related to lifestyle
18.2
6.3
9
5
S52.0
ICD-10 Finland
Fracture of upper end of ulna
4.8
6.3
19
40
F10.05
ICD-10 Finland
Alcohol-related acute intoxication with coma
26.9
6.2
8
*
5353A
ICD-9 Finland
Gastritis and duodenitis, Alcoholic gastritis
26.9
6.2
8
*
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
3.7
6.2
25
69
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
4.0
6.2
23
59
SPAT1294
SPAT
Other function in accordance with health social work nomenclature
4.0
6.2
23
59
SPAT1245
SPAT
Provision of support and information to patient’s family members
2.7
6.2
40
153
J01DA01
ATC
[U] cefalexin; systemic
1.5
6.2
408
3378
S30.0
ICD-10 Finland
Contusion of lower back and pelvis
3.3
6.2
29
91
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
0.6
6.2
128
1872
K22.1
ICD-10 Finland
Ulcer of oesophagus
3.8
6.1
24
65
I95.1
ICD-10 Finland
Orthostatic hypotension
3.1
6.1
31
103
N03AX09
ATC
lamotrigine; oral
3.1
6.1
31
103
F34.1
ICD-10 Finland
Dysthymia
3.4
6.1
27
81
E87.0
ICD-10 Finland
Hyperosmolality and hypernatraemia
12.6
6.1
10
8
5770D
ICD-9 Finland
Diseases of pancreas, Acute pancreatitis[PANCREATITIS ACUTA ALCOHOLICA NONHAEMORHAGICA]
8.7
6.1
12
14
S27.1
ICD-10 Finland
Traumatic haemothorax
8.7
6.1
12
14
S01.7
ICD-10 Finland
Multiple open wounds of head
6.8
6.1
14
21
F10.22
ICD-10 Finland
Alcohol dependence is currently on clinically controlled discontinuation medication
10.1
6.0
11
11
WX730
NOMESCO Finland
Conventional respirator
4.0
6.0
22
56
OAA65
SPAT
NA
0.1
6.0
*
206
S06.2
ICD-10 Finland
Diffuse brain injury
5.6
6.0
16
29
R13
ICD-10 Finland
Dysphagia
2.3
6.0
54
247
D07BA04
ATC
hydrocortisone and antiseptics; topical
2.1
6.0
64
318

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: ALCONEURODEGEN – Degeneration of nervous system due to alcohol

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).