adult-onset Still's disease: adult-onset Still disease (AOSD) is a rare inflammatory multisystem disorder characterized clinically by fever of unknown origin, arthralgia or arthritis, hyperleucocytosis, and typical skin rash.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
150 |
4. Check minimum number of eventsNone |
150 |
5. Include endpointsNone |
150 |
6. Filter based on genotype QC (FinnGen only) |
150 |
Control definitions (FinnGen only)
- Control exclude
- ILD_SYST_AUTO_DISEASES
Extra metadata
- First used in FinnGen datafreeze
- DF5
- Parent code in ICD-10
- M06
- Name in latin
- Arthritis rheumatoides seronegativa
Similar endpoints
↥List of similar endpoints to
Adult-onset Still disease
based on the number of shared cases.
Similar with more cases:
- Other (seronegative) rheumatoid arthritis, wide
- Rheumatoid arthritis
- Rheumatoid arthritis, including avohilmo
- Polyarthropathies
- Autoimmune diseases related-to ILD
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 695 | 385 | 303 |
| Only index persons | 637 | 353 | 284 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 49.30 | 49.81 | 48.68 |
| Only index persons | 47.00 | 47.43 | 46.47 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 150 | 92 | 58 |
| Unadjusted period prevalence (%) | 0.03 | 0.03 | 0.03 |
| Median age at first event (years) | 45.82 | 44.32 | 48.21 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 142
- Matched controls
- 1422
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M06.1
ICD-10 Finland
Adult-onset Still disease
+∞
205.2
142
*
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
73.1
86.0
99
43
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
41.3
62.8
81
44
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
74.1
52.4
58
13
P01BA02
ATC
hydroxychloroquine; oral
28.1
44.7
63
39
H02AB06
ATC
prednisolone; systemic
17.4
42.4
125
422
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
67.0
40.9
46
10
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
27.3
39.1
55
32
R50.9
ICD-10 Finland
Fever, unspecified
14.0
37.1
72
97
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
71.2
36.8
41
8
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
43.2
36.7
45
15
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
10.6
36.0
96
234
A07EC01
ATC
sulfasalazine; oral, rectal
22.7
33.7
50
33
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
19.0
30.4
48
37
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
21.6
28.2
42
27
M05BA04
ATC
alendronic acid; oral
16.3
26.4
44
38
GD1AA
NOMESCO Finland
Thorax X-ray examination
6.6
24.3
93
318
H02AB07
ATC
prednisone; oral
9.2
21.9
50
79
M08.2
ICD-10 Finland
Juvenile arthritis with systemic onset
+∞
21.4
20
*
L04AC03
ATC
anakinra; parenteral
+∞
20.3
19
*
M13.9
ICD-10 Finland
Arthritis, unspecified
13.0
19.9
36
36
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
26.2
19.0
26
12
L04AX01
ATC
azathioprine; systemic
27.2
18.5
25
11
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
12.7
16.1
29
28
L04AA13
ATC
leflunomide; oral
25.7
16.1
22
10
L04AA01
ATC
[U] ciclosporin; systemic
32.9
15.7
20
7
L88
ICPC
Rheumatoid/seropositive arthritis
17.8
15.5
24
16
A49.9
ICD-10 Finland
Bacterial infection, unspecified
7.2
13.2
33
57
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
5.7
12.6
39
89
L04AB04
ATC
adalimumab; parenteral
51.4
12.1
14
*
L04AD01
ATC
ciclosporin; systemic
18.5
12.0
18
11
M08.0
ICD-10 Finland
Juvenile rheumatoid arthritis
130.1
11.6
12
*
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
22.3
11.4
16
8
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
27.7
11.4
15
6
7143A
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Juvenile chronic polyarthritis[MB STILL]
+∞
10.5
10
*
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
5.6
10.0
30
65
NF1AA
NOMESCO Finland
Hip X-ray examination
7.2
9.6
23
37
252
Kela drug reimbursment
NA
+∞
9.5
9
*
3053
Kela drug reimbursment
NA
+∞
9.5
9
*
M01CB01
ATC
sodium aurothiomalate; parenteral
17.7
8.7
13
8
A02BC02
ATC
pantoprazole; systemic
3.1
8.7
103
657
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
8.8
8.7
18
23
ZX120
NOMESCO Finland
Intravenous
5.9
8.7
24
47
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
29.6
8.6
11
*
M08.3
ICD-10 Finland
Juvenile polyarthritis (seronegative)
+∞
8.4
8
*
L04AC07
ATC
tocilizumab; parenteral
47.6
7.8
9
*
JN6DR
NOMESCO Finland
PET-CT of whole body metabolism
47.6
7.8
9
*
NDG30
NOMESCO Finland
Fusion of wrist, total
47.6
7.8
9
*
M06.8
ICD-10 Finland
Other specified rheumatoid arthritis
84.3
7.5
8
*
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
84.3
7.5
8
*
L04AB06
ATC
golimumab; parenteral
84.3
7.5
8
*
L04AA11
ATC
[U] etanercept; parenteral
84.3
7.5
8
*
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
5.3
7.4
22
47
L04AA14
ATC
[U] anakinra; parenteral
+∞
7.3
7
*
L04AB01
ATC
etanercept; parenteral
21.3
7.2
10
5
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
6.3
7.0
18
32
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
11.8
6.9
12
11
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.0
6.9
46
196
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
17.8
6.8
10
6
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
9.4
6.7
13
15
M06.4
ICD-10 Finland
Inflammatory polyarthropathy
73.0
6.5
7
*
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
73.0
6.5
7
*
NG1AE
NOMESCO Finland
Knee joint ultrasound exmination
73.0
6.5
7
*
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
4.4
6.5
23
60
NG1DA
NOMESCO Finland
X-ray of knees
28.0
6.3
8
*
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
+∞
6.3
6
*
L04AA17
ATC
[U] adalimumab; parenteral
+∞
6.3
6
*
M46.1
ICD-10 Finland
Sacroiliitis, not elsewhere classified
+∞
6.3
6
*
NK5AT
NOMESCO Finland
Joint injection with ultrasound guidance not elsewhere classified
+∞
6.3
6
*
O99.1
ICD-10 Finland
Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
+∞
6.3
6
*
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(42870588) Differential panel, method unspecified - Blood
106
337
8.31
35.70
14.5
4.6
—
—
—
0
0
(3013115) Eosinophils [#/volume] in Blood
123
558
7.69
25.24
17.2
5.1
e9/l
0.2
0.2
0.32
117
494
(3037522) Nuclear Ab [Titer] in Serum
61
152
6.08
25.09
1.8
1.3
titre
200.0
470.0
0.96
16
32
(3006315) Basophils [#/volume] in Blood
121
545
7.31
24.90
16.5
4.7
e9/l
0.0
0.0
1.88
116
476
(3001604) Monocytes [#/volume] in Blood
120
541
7.09
24.52
16.6
4.7
e9/l
0.6
0.5
2.41
115
474
(3019198) Lymphocytes [#/volume] in Blood
120
561
6.70
22.89
17.2
4.7
e9/l
1.9
2.0
0.45
115
502
(3007847) Interleukin 2 Receptor Soluble [Units/volume] in Serum or Plasma
17
10
19.05
20.60
4.6
2.0
u/ml
1215.4
1059.9
—
17
10
(3013650) Neutrophils [#/volume] in Blood by Automated count
124
640
6.41
19.78
19.6
9.0
e9/l
4.4
4.0
1.15
118
557
(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum
23
25
10.69
19.61
1.3
1.1
—
—
—
0
0
(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay
20
19
11.99
18.62
1.3
1.4
—
—
—
0
0
(3023368) Bacteria identified in Blood by Culture
69
238
4.52
18.38
6.2
4.1
—
—
—
0
0
(3007080) Epstein Barr virus nuclear IgG Ab [Units/volume] in Serum
19
17
12.65
18.35
1.3
1.4
u/ml
312.3
145.6
—
14
9
(3021788) Differential panel - Synovial fluid
16
11
16.16
17.89
1.7
1.2
—
—
—
0
0
(3001122) Ferritin [Mass/volume] in Serum or Plasma
104
517
4.30
16.04
8.7
2.5
ug/l
235.9
97.2
1.95
99
479
(3048929) Epstein Barr virus Ab [Presence] in Serum
24
38
7.33
15.06
1.5
1.3
—
—
—
0
0
(3032035) Polymorphonuclear cells/100 leukocytes in Blood
14
12
12.76
13.72
4.9
2.0
%
56.4
59.1
0.19
14
12
(3030905) Polymorphonuclear cells [#/volume] in Blood
14
12
12.76
13.72
4.1
2.0
e9/l
4.7
4.5
0.05
14
12
(3050238) Crystals [Presence] in Synovial fluid by Light microscopy
16
18
9.83
13.13
2.1
1.3
—
—
—
0
0
(4062490)
13
11
12.84
12.80
1.4
1.3
—
—
—
0
0
(3002179) Metamyelocytes/100 leukocytes in Blood
31
74
5.02
12.71
9.2
3.9
%
1.0
0.5
0.62
11
21
(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma
17
23
8.21
12.10
1.2
1.4
—
—
—
0
0
(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma
131
864
5.08
11.62
17.1
6.6
u/l
70.4
76.5
1.25
126
811
(3021440) Promyelocytes/100 leukocytes in Blood
30
76
4.68
11.40
11.0
3.9
%
0.1
0.1
0.15
12
24
(3017181) Myelocytes/100 leukocytes in Blood
31
81
4.56
11.34
10.7
3.8
%
0.8
0.7
0.13
13
27
(3004588) Protein electrophoresis panel - Serum or Plasma
23
48
5.48
10.89
1.7
1.8
—
—
—
0
0
(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence
14
17
8.98
10.79
1.2
1.1
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
122
792
3.90
10.44
9.8
3.7
—
—
—
0
0
(3025159) Blasts/100 leukocytes in Blood
28
74
4.42
10.04
11.1
3.8
%
0.0
0.4
—
10
22
(3034780) Angiotensin converting enzyme [Enzymatic activity/volume] in Serum or Plasma
23
53
4.94
9.72
1.8
2.4
u/l
40.1
42.9
0.22
23
47
(3009261) Glucose [Presence] in Urine by Test strip
99
582
3.06
9.71
5.4
3.2
estimate
0.0
0.0
0.00
21
103
(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection
11
11
10.71
9.66
1.4
1.8
—
—
—
0
0
(3012447) Hantavirus puumala IgG Ab [Titer] in Serum
11
11
10.71
9.66
1.1
1.1
—
—
—
0
0
(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection
11
11
10.71
9.66
1.6
1.5
—
—
—
0
0
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
15
23
7.14
9.54
1.5
1.7
—
—
—
0
0
(3021589) Normoblasts [#/volume] in Blood
88
494
2.89
9.25
22.1
7.3
e9/l
0.0
0.0
0.39
78
407
(3035350) Ketones [Presence] in Urine by Test strip
97
577
2.93
9.08
5.4
3.0
estimate
0.0
0.0
0.00
19
108
(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
13
18
7.81
8.99
1.5
1.9
—
—
—
0
0
(3021601) Nitrite [Presence] in Urine by Test strip
96
575
2.86
8.74
7.8
4.2
estimate
0.0
0.0
0.00
21
107
(3023420) DNA double strand Ab [Units/volume] in Serum
13
8
17.62
8.72
1.8
1.1
—
—
—
0
0
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
14
22
6.92
8.69
1.5
1.7
—
—
—
0
0
(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay
18
37
5.39
8.61
1.7
1.5
—
—
—
0
0
(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection
11
13
9.05
8.57
1.4
1.8
—
—
—
0
0
(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection
11
13
9.05
8.57
1.4
1.7
—
—
—
0
0
(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection
12
16
8.07
8.54
1.3
1.7
—
—
—
0
0
(3042111) Morphology [Interpretation] in Bone marrow Narrative
10
11
9.67
8.18
1.2
1.5
—
—
—
0
0
(3024561) Albumin [Mass/volume] in Serum or Plasma
74
402
2.66
7.96
5.3
3.9
g/l
33.7
36.7
3.15
69
383
(3023150) Myeloperoxidase Ab [Units/volume] in Serum
12
18
7.16
7.73
2.3
1.1
—
—
—
0
0
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
83
482
2.62
7.72
8.2
5.7
mmol/l
1.2
1.2
0.72
73
412
(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells
14
25
6.07
7.70
1.4
1.8
—
—
—
0
0
(40760888) Immunoglobulin light chains.free panel - Serum
10
12
8.86
7.67
1.8
2.5
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
70
377
2.61
7.57
4.5
2.6
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
30
102
3.43
7.48
1.7
1.6
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
39
156
3.03
7.45
2.2
1.8
—
—
—
0
0
(3037756) Immunofixation for Serum or Plasma
11
16
7.34
7.25
1.6
1.3
—
—
—
0
0
(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay
13
23
6.09
7.20
1.3
1.2
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
29
100
3.36
7.06
1.8
1.6
—
—
—
0
0
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
15
32
5.10
6.85
1.8
1.5
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
54
270
2.56
6.66
12.0
3.9
—
—
—
0
0
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
47
220
2.65
6.63
1.4
1.2
u/ml
44.9
8.1
1.19
21
86
(3017143) Hepatitis C virus Ab [Presence] in Serum
36
147
2.91
6.57
1.6
1.6
—
—
—
0
0
(40768443) Skin Pathology biopsy report
17
42
4.44
6.55
1.4
1.1
—
—
—
0
0
(3005322) IgE [Units/volume] in Serum or Plasma
25
84
3.37
6.31
1.5
1.2
u/ml
134.9
149.7
0.10
25
75
(36304052) Adalimumab Ab [Units/volume] in Serum or Plasma
6
0
+∞
6.29
1.7
0.0
—
—
—
0
0
(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum
11
19
6.17
6.20
1.2
1.3
—
—
—
0
0
(3026782) Osmolality of Urine
42
192
2.65
6.16
3.6
2.2
mosm/kgh2o
481.0
583.3
2.11
36
168
(3021879) Hepatitis B virus core Ab [Presence] in Serum
26
91
3.25
6.15
1.4
1.6
—
—
—
0
0
(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma
76
460
2.32
6.01
6.2
4.9
mmol/l
1.2
1.2
0.43
68
414
(40766800) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells [Units/volume] corrected for background in Blood
9
6
15.83
5.98
1.7
1.3
—
—
—
0
0
(3000093) Morphology [Interpretation] in Blood Narrative
9
6
15.83
5.98
1.2
1.2
—
—
—
0
0
(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma
47
231
2.51
5.92
1.4
1.2
iu/ml
45.8
34.4
0.33
22
76
(40758558) Short blood count panel - Blood
54
287
2.38
5.71
15.5
7.3
—
—
—
0
0
(3000850) Epithelial cells [#/volume] in Urine
43
206
2.52
5.70
3.3
2.2
e6/l
4.2
5.2
0.19
36
190
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
50
257
2.42
5.69
1.5
1.5
—
—
—
0
0
(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection
9
7
13.57
5.66
1.8
1.3
—
—
—
0
0
(3048689) Calprotectin [Mass/mass] in Stool
31
127
2.82
5.58
2.2
1.3
ug/g
84.2
71.9
0.18
26
98
(3045142) Bone marrow Pathology biopsy report
9
8
11.86
5.36
1.1
1.3
—
—
—
0
0
(3015736) pH of Urine
74
460
2.20
5.31
5.2
2.9
—
—
—
0
0
(3045424) Erythrocytes [Presence] in Urine
10
19
5.57
5.11
3.2
1.5
—
—
—
0
0
(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis
11
24
4.87
4.86
1.9
1.3
g/l
0.0
0.0
0.00
11
24
(3018095) Leukocytes [#/volume] in Urine
64
388
2.13
4.77
5.0
3.1
e6/l
40.2
36.3
0.05
48
271
(3030467) Casts [#/volume] in Urine by Automated count
51
283
2.22
4.75
3.3
2.5
e6/l
0.1
0.3
1.14
41
206
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
33
151
2.52
4.75
1.3
1.4
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
48
261
2.23
4.69
5.1
3.3
—
—
—
0
0
(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection
7
5
14.58
4.62
1.6
1.4
—
—
—
0
0
(3045414) Leukocytes [Presence] in Urine
15
44
3.68
4.60
2.8
1.4
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
41
211
2.30
4.55
1.7
1.7
—
—
—
0
0
(3007164) IgA [Mass/volume] in Serum or Plasma
48
264
2.20
4.54
2.0
1.4
g/l
2.1
2.2
0.47
41
159
(3002582) Erythrocytes [#/volume] in Urine
55
320
2.13
4.52
3.5
2.5
e6/l
18.7
240.8
0.57
46
247
(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma
43
228
2.24
4.44
3.8
1.9
mg/l
2.9
3.2
0.52
37
190
(3031040) Bacteria [#/volume] in Urine by Automated count
102
751
2.12
4.39
5.1
3.8
—
52.1
—
0
14
(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence
8
9
9.31
4.33
1.3
1.0
—
—
—
0
0
(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay
13
36
3.86
4.31
1.1
1.3
—
—
—
0
0
(3016650) Hepatitis A virus Ab [Presence] in Serum
10
23
4.59
4.15
1.2
1.1
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
47
266
2.12
4.09
1.8
2.0
—
—
—
0
0
(3023520) Reticulocytes [#/volume] in Blood
20
76
2.88
4.09
3.9
2.6
e9/l
71.9
72.0
0.00
14
59
(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot
8
11
7.61
3.91
1.4
1.2
—
—
—
0
0
(40759836) Histone Ab [Presence] in Serum by Immunoblot
8
11
7.61
3.91
1.4
1.2
—
—
—
0
0
(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot
8
11
7.61
3.91
1.4
1.2
—
—
—
0
0
(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot
8
11
7.61
3.91
1.4
1.2
—
—
—
0
0
(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot
8
11
7.61
3.91
1.4
1.2
—
—
—
0
0
(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot
8
11
7.61
3.91
1.4
1.2
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
49
288
2.04
3.83
3.2
2.4
—
—
—
0
0
(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection
6
5
12.42
3.79
2.0
1.2
—
—
—
0
0
(3044941) Cell count panel - Synovial fluid
7
9
8.09
3.60
1.1
1.2
—
—
—
0
0
(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay
12
36
3.54
3.56
1.0
1.1
—
—
—
0
0
(3029937) Albumin [Presence] in Urine by Test strip
51
312
1.96
3.53
5.6
3.3
estimate
0.0
0.0
0.00
21
104
(21493690) Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood
6
6
10.34
3.53
2.3
2.7
—
—
—
0
0
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
23
102
2.48
3.50
3.0
3.0
—
—
—
0
0
(3019225) pH of Specimen
23
102
2.48
3.50
4.7
4.5
—
—
—
0
0
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
139
1206
3.08
3.46
32.6
10.7
mg/l
25.9
21.3
0.81
128
904
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
62
409
1.88
3.40
4.4
3.3
ng/l
21.1
27.4
0.35
46
244
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
14
48
3.11
3.40
5.6
4.9
mmol/l
26.1
25.5
0.16
14
48
(3004616) Nuclear Ab [Presence] in Serum
8
15
5.57
3.23
1.4
1.2
—
—
—
0
0
(3047007) Chlamydophila sp Ab [Presence] in Serum
8
15
5.57
3.23
1.1
1.1
—
—
—
0
0
(40768795) Lymph node Pathology biopsy report
7
11
6.61
3.22
1.1
1.4
—
—
—
0
0
(43055554) Base excess.100% oxygenated [Moles/volume] standard in Capillary blood by calculation
15
56
2.87
3.16
4.9
2.9
mmol/l
2.1
1.3
—
10
48
(44790048)
6
8
7.75
3.08
1.2
1.6
—
—
—
0
0
(44790049)
6
8
7.75
3.08
1.2
1.6
—
—
—
0
0
(44790047)
6
8
7.75
3.08
1.2
1.6
—
—
—
0
0
(44806118)
6
8
7.75
3.08
1.2
1.6
—
—
—
0
0
(3021901) Oxygen saturation in Capillary blood
7
12
6.06
3.05
2.9
1.9
—
—
—
0
0
(3036071) Salmonella sp Ab [Titer] in Serum
5
5
10.28
3.00
1.4
1.0
—
—
—
0
0
(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay
8
17
4.91
2.96
1.0
1.1
—
—
—
0
0
(3018418) pH of Serum or Plasma
47
295
1.86
2.95
4.7
3.5
ph
7.4
7.4
—
6
54
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
31
169
2.05
2.91
2.7
2.3
e6/l
1.1
1.0
0.06
17
90
(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay
8
18
4.63
2.83
1.1
1.5
—
—
—
0
0
(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay
8
18
4.63
2.83
1.1
1.5
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
16
66
2.59
2.82
2.0
1.5
—
—
—
0
0
(3009550) Parvovirus B19 IgG Ab [Titer] in Serum
5
6
8.56
2.77
1.2
1.2
—
—
—
0
0
(46235128) Lupus anticoagulant aPTT and dRVVT screening panel W Reflex
5
6
8.56
2.77
1.4
1.3
—
—
—
0
0
(3026515) Parvovirus B19 IgM Ab [Units/volume] in Serum
5
6
8.56
2.77
1.2
1.2
—
—
—
0
0
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
11
37
3.13
2.75
1.3
1.5
—
—
—
0
0
(3024891) Influenza virus A+B Ag [Presence] in Specimen
11
37
3.13
2.75
1.0
1.2
—
—
—
0
0
(1616796) Gas panel - Central venous blood
6
10
6.20
2.72
2.5
1.6
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
25
129
2.13
2.70
2.5
1.7
—
—
—
0
0
(3013742) Prealbumin [Mass/volume] in Serum or Plasma
18
81
2.39
2.66
2.4
2.3
g/l
0.2
0.2
0.42
18
73
(3022313) Gas panel - Capillary blood
13
50
2.75
2.61
5.0
2.7
—
—
—
0
0
(3014148) Varicella zoster virus Ab [Titer] in Serum
6
11
5.63
2.57
1.0
1.2
—
—
—
0
0
(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability
5
7
7.34
2.57
1.0
1.4
—
—
—
0
0
(3013512) EKG study
48
315
1.77
2.57
4.0
3.2
—
—
—
0
0
(3002523) Influenza virus A Ag [Presence] in Specimen
9
26
3.61
2.52
1.1
1.1
—
—
—
0
0
(3003740) Influenza virus B Ag [Presence] in Specimen
9
26
3.61
2.52
1.1
1.1
—
—
—
0
0
(3032080) INR in Blood by Coagulation assay
56
386
1.72
2.51
8.6
5.7
inr
1.1
1.1
0.05
17
115
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
10
34
3.08
2.46
3.5
1.9
—
—
—
0
0
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
28
157
1.96
2.43
2.6
2.4
e6/l
2.4
3.6
0.36
14
79
(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay
6
12
5.16
2.42
1.0
1.1
—
—
—
0
0
(3051611) Lipemic interference index of Serum or Plasma
6
12
5.16
2.42
2.5
3.2
—
—
—
0
0
(3028679) Herpes simplex virus Ab [Presence] in Serum
5
8
6.42
2.39
1.4
1.0
—
—
—
0
0
(40766048) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum by Immunoassay
5
8
6.42
2.39
1.6
1.3
—
—
—
0
0
(3019420) Tryptase [Mass/volume] in Serum or Plasma
5
8
6.42
2.39
1.8
1.5
ug/l
3.3
9.0
—
5
8
(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal
5
8
6.42
2.39
1.2
1.4
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
22
115
2.07
2.30
2.0
1.3
—
—
—
0
0
(3027238) Thyroperoxidase Ab [Units/volume] in Serum or Plasma
19
94
2.17
2.28
1.2
1.2
iu/ml
41.1
155.6
—
7
35
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
129
1136
1.97
2.20
22.9
9.9
ml/min/173m2
87.4
86.8
0.11
112
931
(3013327) Hepatitis A virus IgM Ab [Presence] in Serum
7
19
3.81
2.18
1.0
1.1
—
—
—
0
0
(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection
6
14
4.42
2.17
1.0
2.4
—
—
—
0
0
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
8
25
3.32
2.13
1.5
1.2
—
—
—
0
0
(3016914) Bacteria identified in Cerebral spinal fluid by Culture
5
10
5.13
2.08
1.2
1.6
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
62
462
1.58
1.97
6.0
3.0
—
—
—
0
0
(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay
5
11
4.66
1.95
1.0
1.1
—
—
—
0
0
(3030366) Cystatin C [Mass/volume] in Serum or Plasma
7
22
3.28
1.90
3.3
3.2
mg/l
1.3
1.2
—
7
22
(3041096) Erythrocytes [Presence] in Urine by Automated
48
340
1.61
1.87
5.2
2.4
—
—
—
0
0
(3000492) Spirometry study
5
135
0.35
1.87
1.2
1.5
—
—
—
0
0
(3014765) Yersinia sp identified in Stool by Organism specific culture
9
35
2.67
1.83
1.3
1.2
—
—
—
0
0
(42529406) Shigella sp [Presence] in Stool by Culture
9
35
2.67
1.83
1.3
1.2
—
—
—
0
0
(3003458) Phosphate [Moles/volume] in Serum or Plasma
22
127
1.86
1.76
7.3
3.9
mmol/l
1.1
1.0
0.66
22
117
(3018171) Choriogonadotropin [Units/volume] in Serum or Plasma
11
48
2.39
1.75
1.3
2.6
u/l
26048.6
406.0
—
5
16
(3004248) Sex hormone binding globulin [Moles/volume] in Serum or Plasma
0
46
0.00
1.74
0.0
1.5
—
39.8
—
0
46
(4035726)
17
90
2.00
1.73
1.5
1.3
—
—
—
0
0
(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection
5
13
3.94
1.73
1.2
2.1
—
—
—
0
0
(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection
5
13
3.94
1.73
1.2
2.1
—
—
—
0
0
(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection
5
13
3.94
1.73
1.0
2.5
—
—
—
0
0
(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection
5
13
3.94
1.73
1.2
2.1
—
—
—
0
0
(3013826) Glucose [Moles/volume] in Serum or Plasma
83
677
1.51
1.67
5.3
3.9
mmol/l
6.5
6.5
0.07
78
619
(3022621) pH of Urine by Test strip
14
70
2.10
1.65
3.6
2.4
—
—
—
0
0
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
10
43
2.42
1.64
2.7
2.2
—
—
—
0
0
(3008757) Leukocyte morphology finding [Identifier] in Blood
5
14
3.66
1.63
3.6
3.1
—
—
—
0
0
(3041354) Potassium [Moles/volume] in Venous blood
5
14
3.66
1.63
3.6
2.2
mmol/l
4.1
4.0
—
5
14
(3035285) Chloride [Moles/volume] in Venous blood
5
14
3.66
1.63
3.6
2.2
mmol/l
106.8
105.2
—
5
14
(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection
7
26
2.77
1.60
1.6
1.8
—
—
—
0
0
(3027529) Toxoplasma gondii IgM Ab [Units/volume] in Serum
5
15
3.41
1.53
1.2
1.6
—
—
—
0
0
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
7
27
2.67
1.53
4.3
1.2
—
—
—
0
0
(3008037) Lactate [Moles/volume] in Venous blood
6
21
2.93
1.52
6.0
2.1
mmol/l
1.1
1.3
—
6
21
(3002256) Pathology report gross observation
22
134
1.75
1.49
1.8
1.2
—
—
—
0
0
(3000067) Parathyrin.intact [Mass/volume] in Serum or Plasma
13
67
2.03
1.43
2.9
3.5
ng/l
62.7
74.2
0.28
13
60
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
11
53
2.16
1.42
1.7
1.5
—
—
—
0
0
(3036489) Thrombin time
9
41
2.27
1.39
5.6
1.7
s
22.3
20.6
—
9
34
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
6
23
2.67
1.38
2.8
1.4
—
—
—
0
0
(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing
5
17
3.00
1.37
2.2
1.4
—
—
—
0
0
(3027315) Oxygen [Partial pressure] in Blood
5
17
3.00
1.37
2.6
1.5
kpa
7.9
8.6
—
5
17
(3013290) Carbon dioxide [Partial pressure] in Blood
5
17
3.00
1.37
2.6
1.5
kpa
5.5
5.0
—
5
17
(3019832) Treponema pallidum Ab [Presence] in Serum
24
155
1.65
1.33
1.4
1.7
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
37
266
1.52
1.32
3.0
2.1
—
—
—
0
0
(3006418) Campylobacter sp identified in Tissue by Organism specific culture
8
34
2.43
1.31
1.5
1.2
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
16
92
1.83
1.31
6.4
2.9
—
—
—
0
0
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
105
922
1.46
1.31
4.4
3.8
pmol/l
14.9
14.5
0.85
95
860
(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum
5
18
2.84
1.29
2.4
2.9
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
40
294
1.49
1.29
4.0
2.4
—
—
—
0
0
(40761535) Cells panel - Urine sediment
15
86
1.83
1.24
7.2
3.4
—
—
—
0
0
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
27
184
1.57
1.22
4.6
3.0
ng/l
199.8
209.8
0.02
20
132
(3012516) Albumin [Mass/volume] in Urine
39
289
1.47
1.20
3.8
3.1
mg/l
2195.7
290.7
0.41
25
184
(3038515) Glucose [Moles/volume] in Venous blood
5
20
2.55
1.16
7.0
2.1
mmol/l
5.8
7.5
—
5
20
(40761511) CBC panel - Blood by Automated count
137
1285
1.76
1.14
20.1
10.2
—
—
—
0
0
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
50
393
1.41
1.13
2.3
1.8
pmol/l
91.0
94.9
0.22
34
194
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
66
544
1.38
1.13
4.7
3.7
—
—
—
0
0
(3023081) Carboxyhemoglobin/Hemoglobin.total in Blood
7
31
2.32
1.12
3.1
3.5
%
1.4
1.4
—
7
26
(3004716) Salmonella sp identified in Stool by Organism specific culture
13
74
1.83
1.10
1.7
1.4
—
—
—
0
0
(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood
9
48
1.93
1.02
6.8
2.5
%
49.2
53.7
—
9
48
(3000494) Fungus identified in Specimen by Culture
20
133
1.58
1.01
1.4
1.3
—
—
—
0
0
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
120
1102
1.44
1.00
5.0
4.5
mu/l
1.8
1.8
0.31
109
1021
(3010421) pH of Blood
5
23
2.21
0.99
2.6
1.7
ph
7.4
7.4
—
5
17
(3044640) Blood type and Crossmatch panel - Blood
45
355
1.38
0.98
3.3
2.1
—
—
—
0
0
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
9
153
0.56
0.95
1.3
1.8
—
—
—
0
0
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
8
42
1.95
0.90
2.5
1.9
—
—
—
0
0
(3018677) aPTT in Platelet poor plasma by Coagulation assay
20
138
1.52
0.87
3.9
1.7
s
27.7
29.2
0.83
20
132
(3000330) Specific gravity of Urine by Test strip
8
45
1.82
0.86
8.1
2.2
—
—
—
0
0
(3052851) Hemolysis interference index of Serum or Plasma
6
31
1.97
0.85
3.8
3.2
—
—
—
0
0
(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma
34
263
1.38
0.83
5.9
2.7
ng/l
579.4
792.2
0.76
28
218
(3025941) Bacteria identified in Stool by Culture
10
58
1.78
0.82
1.9
1.2
—
—
—
0
0
(3039443) Prostate specific Ag panel - Serum or Plasma
0
25
0.00
0.80
0.0
1.4
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
97
876
1.30
0.79
3.6
3.4
—
—
—
0
0
(3009508) Creatinine [Moles/volume] in Urine
40
322
1.33
0.76
3.7
2.8
mmol/l
7.7
7.9
0.07
30
275
(3020682) Albumin/Creatinine [Ratio] in Urine
38
304
1.33
0.76
4.7
3.7
mg/mmol
13.4
8.4
0.31
25
185
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
10
60
1.71
0.74
1.3
1.3
—
—
—
0
0
(3008898) HLA-B27 [Presence]
9
58
1.59
0.71
1.0
1.1
—
—
—
0
0
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
6
105
0.55
0.64
1.0
1.6
—
—
—
0
0
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
23
177
1.35
0.59
1.3
2.1
—
—
—
0
0
(3000991) Gas panel - Venous blood
11
73
1.55
0.58
10.1
5.8
—
—
—
0
0
(3019150) Specific gravity of Urine by Refractometry
32
260
1.29
0.57
5.5
3.2
kg/l
1.0
1.0
—
6
30
(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma
22
169
1.35
0.57
2.5
2.9
mmol/l
2.4
2.5
0.58
22
152
(3017895) Helicobacter pylori Ab [Units/volume] in Serum
6
38
1.60
0.55
1.0
1.7
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
14
100
1.44
0.54
1.1
1.2
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
55
484
1.22
0.50
2.3
1.9
—
—
—
0
0
(3003327) Ova and parasites identified in Stool by Light microscopy
7
46
1.55
0.49
3.3
1.5
—
—
—
0
0
(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection
7
48
1.48
0.47
2.1
1.4
—
—
—
0
0
(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma
7
49
1.45
0.46
1.3
1.8
—
—
—
0
0
(3027273) Bicarbonate [Moles/volume] in Venous blood
7
50
1.42
0.45
5.9
2.1
mmol/l
26.9
24.8
—
7
50
(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection
6
93
0.63
0.44
1.2
2.1
—
—
—
0
0
(3004119) Hemoglobin [Mass/volume] in Venous blood
8
57
1.43
0.43
5.4
2.2
g/l
112.6
133.7
—
8
57
(3050129) First trimester maternal screen panel - Serum or Plasma
8
58
1.40
0.42
1.3
1.4
—
—
—
0
0
(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight
0
15
0.00
0.41
0.0
1.6
—
—
—
0
0
(3038177) Helicobacter pylori Ab [Presence] in Serum
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
(3027946) Carbon dioxide [Partial pressure] in Arterial blood
14
107
1.34
0.39
8.8
5.6
kpa
4.9
5.2
0.50
14
100
(3027801) Oxygen [Partial pressure] in Arterial blood
14
107
1.34
0.39
8.6
5.6
kpa
12.2
12.6
0.15
14
101
(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma
22
181
1.25
0.37
2.4
1.6
pmol/l
438.1
435.8
0.02
17
159
(3005033) Fetal Nuchal fold Thickness US
6
41
1.48
0.36
1.2
1.3
—
—
—
0
0
(3047352) Trisomy 18 risk [Likelihood] in Fetus
6
41
1.48
0.36
1.2
1.3
—
—
—
0
0
(3043238) Trisomy 21 risk [Likelihood] in Fetus
6
43
1.41
0.35
1.2
1.5
—
—
—
0
0
(3022145) Colonoscopy Study observation
15
118
1.30
0.35
1.3
1.2
—
—
—
0
0
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
19
229
0.80
0.33
3.5
3.9
%
18.7
21.9
—
10
89
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
33
288
1.19
0.33
1.3
1.3
u/ml
2.6
1.9
—
7
84
(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma
6
47
1.29
0.32
1.2
1.4
—
—
—
0
0
(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age
6
47
1.29
0.32
1.2
1.4
—
—
—
0
0
(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma
6
47
1.29
0.32
1.2
1.4
—
—
—
0
0
(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight
6
47
1.29
0.32
1.2
1.4
—
—
—
0
0
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
7
52
1.36
0.31
2.6
2.1
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
45
495
0.87
0.29
3.2
2.6
—
—
—
0
0
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
118
1216
0.86
0.26
4.7
4.0
mmol/l
1.5
1.5
0.49
111
1135
(4034850)
5
40
1.26
0.22
5.6
7.4
—
—
—
0
0
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
115
1115
1.13
0.22
4.6
4.8
mmol/mol
36.9
38.8
2.13
107
1052
(3003396) Base excess in Arterial blood by calculation
13
107
1.24
0.22
8.7
5.7
mmol/l
2.5
1.6
—
8
78
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
5
42
1.20
0.21
8.8
5.8
—
—
—
0
0
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
119
1221
0.88
0.21
4.7
4.0
mmol/l
4.8
4.8
0.15
112
1146
(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma
0
10
0.00
0.21
0.0
1.8
—
1.0
—
0
10
(3024666) Lithium, Blood [Moles/volume] in Serum or Plasma
0
10
0.00
0.21
0.0
7.0
—
0.7
—
0
10
(3016244) Insulin [Units/volume] in Serum or Plasma
0
10
0.00
0.21
0.0
3.0
—
17.9
—
0
10
(3008832) Norclozapine [Moles/volume] in Serum or Plasma
0
12
0.00
0.21
0.0
12.3
—
892.9
—
0
12
(3014702) Chromogranin A [Moles/volume] in Serum or Plasma
0
12
0.00
0.21
0.0
2.3
—
3.3
—
0
12
(3000081) cloZAPine [Moles/volume] in Serum or Plasma
0
12
0.00
0.21
0.0
18.8
—
1730.6
—
0
12
(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma
15
176
0.84
0.21
3.3
2.5
ug/l
0.6
0.7
—
8
100
(3025839) Triglyceride [Moles/volume] in Serum or Plasma
34
309
1.13
0.20
2.1
1.7
mmol/l
1.7
1.4
1.10
26
272
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
17
146
1.19
0.20
1.8
1.8
—
—
—
0
0
(21494755) Public health laboratory ask at order entry panel
15
175
0.84
0.20
1.3
1.3
—
—
—
0
0
(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma
6
50
1.21
0.20
1.2
1.6
—
—
—
0
0
(3019060) Gas panel - Arterial blood
7
62
1.14
0.17
1.0
4.2
—
—
—
0
0
(3013139) Helicobacter pylori Ag [Presence] in Stool
9
79
1.15
0.15
1.6
1.3
—
—
—
0
0
(3044889) 12 lead EKG panel
84
811
1.08
0.15
3.9
3.4
—
—
—
0
0
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
12
138
0.86
0.13
5.3
5.7
—
—
—
0
0
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
122
1235
0.93
0.07
4.9
4.4
mmol/l
2.9
2.9
0.13
114
1151
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
17
157
1.09
0.07
1.4
2.0
—
—
—
0
0
(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma
7
84
0.83
0.07
1.1
1.5
—
—
—
0
0
(3001019) Free T4 and TSH panel - Serum or Plasma
7
84
0.83
0.07
1.6
1.7
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
36
345
1.06
0.07
1.5
1.5
—
—
—
0
0
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
115
1161
0.96
0.04
4.3
4.0
mmol/l
5.5
5.8
2.81
107
1086
(40768797) Stomach Pathology biopsy report
16
154
1.04
0.00
1.2
1.3
—
—
—
0
0
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
118
1184
0.98
0.00
4.7
3.6
mmol/l
1.3
1.3
0.25
111
1095
(3009542) Hematocrit [Volume Fraction] of Blood
115
1149
1.00
0.00
26.1
11.4
%
38.2
40.8
1.86
85
920
(3003785) Carcinoembryonic Ag [Mass/volume] in Serum or Plasma
10
97
1.03
0.00
2.6
3.9
ug/l
1.2
10.0
—
5
82
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
25
253
0.99
0.00
1.4
1.4
—
—
—
0
0
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
6
68
0.88
0.00
1.3
1.0
—
—
—
0
0
(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
(3019497) Choriogonadotropin.beta subunit free [Moles/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3034426) Prothrombin time (PT)
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
(37020300) Entamoeba histolytica DNA [Presence] in Stool by NAA with probe detection
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(42868766) Dientamoeba fragilis DNA [Presence] in Stool by NAA with probe detection
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3044242) Glucose [Moles/volume] in Arterial blood
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(36306090) Helicobacter pylori [Presence] in Tissue by Organism specific culture
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.5
—
22.3
—
0
6
(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3017315) Amylase [Enzymatic activity/volume] in Urine
0
9
0.00
0.00
0.0
1.2
—
299.9
—
0
9
(40765089) Chromosome analysis panel - Blood by G-banded
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
(4198724)
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
0
6
0.00
0.00
0.0
2.8
—
111.0
—
0
6
(40768800) Prostate Pathology biopsy report
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
(43055514) Macroprolactin [Presence] in Serum or Plasma
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3030429) Borrelia sp DNA [Identifier] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(4146454)
0
7
0.00
0.00
0.0
2.6
—
—
—
0
0
(3015183) Erythrocyte sedimentation rate
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
(3036428) Adenosine deaminase [Enzymatic activity/volume] in Pleural fluid
0
6
0.00
0.00
0.0
1.2
—
7.2
—
0
6
(3035933) Granulocytes/100 leukocytes in Blood
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
(3016502) Oxygen saturation in Arterial blood
9
93
0.97
0.00
12.7
6.0
%
96.8
95.5
—
9
87
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
5
49
1.02
0.00
4.6
2.0
%
1.1
1.3
—
5
49
(3000012) Reticulocyte production index
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint STILL_ADULT and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| STILL_ADULT | 1.988 [1.4, 2.83] | < 0.001 |
| Birth year | 0.999 [0.99, 1.01] | 0.737 |
During the follow-up period (1.1.1998 — 31.12.2019), 53 out of 328 females with STILL_ADULT died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| STILL_ADULT | 1.642 [1.18, 2.28] | 0.003 |
| Birth year | 0.988 [0.98, 1.0] | 0.009 |
During the follow-up period (1.1.1998 — 31.12.2019), 57 out of 253 males with STILL_ADULT died.
Mortality risk
Mortality risk for people of age
years, who have STILL_ADULT.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.161% | 0.335% |
| 5 | 1.301% | 1.57% |
| 10 | 3.268% | 4.225% |
| 15 | 6.061% | 8.388% |
| 20 | 10.759% | 14.54% |
Relationships between endpoints
↥Index endpoint: STILL_ADULT – Adult-onset Still disease
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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