info icon

This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Secondary sideroblastic anaemia due to drugs and toxins

SECONDA_SIDEROBLASTIC_ANAEM_DRUGS_TOXINS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D64.2#

1 out of 7 registries used, show all original rules.

24

4. Check minimum number of events

None

24

5. Include endpoints

None

24

6. Filter based on genotype QC (FinnGen only)

24

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF5

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 262 166 93
Only index persons 173 112 61
Unadjusted period prevalence (%)
Whole population 0.00 0.00 0.00
Only index persons 0.00 0.00 0.00
Median age at first event (years)
Whole population 70.46 70.82 70.24
Only index persons 68.59 68.69 68.41

-FinnGen-

Key figures

All Female Male
Number of individuals 24 17 7
Unadjusted period prevalence (%) 0.01 0.01 0.00
Median age at first event (years) 67.32 66.12 70.24

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(4281824)
9
0
+∞
10.06
1.6
0.0
—
—
—
0
0
(3030981) Hyaline casts [#/volume] in Urine by Automated count
9
10
13.50
5.33
2.9
3.5
e6/l
0.8
0.0
—
9
10
(3013512) EKG study
17
62
6.91
4.78
3.6
4.2
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
15
60
4.96
3.32
5.3
2.3
—
—
—
0
0
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
9
25
5.11
2.95
2.9
3.2
e6/l
7.2
2.9
—
9
13
(3003694) ABO and Rh group [Type] in Blood
12
46
4.22
2.89
1.6
1.4
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
13
53
4.17
2.88
2.5
2.9
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
14
61
4.11
2.82
2.7
3.6
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
17
87
4.25
2.79
7.5
4.2
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
6
11
6.85
2.72
1.5
2.1
—
—
—
0
0
(3002582) Erythrocytes [#/volume] in Urine
13
56
3.88
2.62
2.8
3.4
e6/l
26.9
1221.3
0.52
13
43
(3021589) Normoblasts [#/volume] in Blood
14
73
3.20
1.96
33.6
10.5
e9/l
0.0
0.0
0.49
14
60
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
14
74
3.14
1.90
4.1
3.4
—
—
—
0
0
(3033658) Prothrombin time (PT) actual/Normal
10
44
3.18
1.83
2.5
3.2
%
96.9
93.6
—
10
44
(3018095) Leukocytes [#/volume] in Urine
13
67
3.05
1.83
5.8
4.3
e6/l
40.8
48.4
0.08
13
46
(4035726)
6
19
3.85
1.79
1.3
1.3
—
—
—
0
0
(3023368) Bacteria identified in Blood by Culture
11
52
3.06
1.78
6.5
4.1
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
9
40
2.98
1.63
1.7
2.3
—
—
—
0
0
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
15
93
2.62
1.53
9.3
5.5
mmol/l
1.2
1.2
0.50
15
75
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
0
39
0.00
1.50
0.0
1.2
—
1.4
—
0
12
(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma
0
40
0.00
1.50
0.0
1.2
—
16.7
—
0
16
(3032080) INR in Blood by Coagulation assay
13
73
2.70
1.49
1.9
9.6
inr
1.1
1.3
—
6
26
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
9
44
2.66
1.47
1.4
1.6
mg/l
1.8
0.9
—
9
39
(3013650) Neutrophils [#/volume] in Blood by Automated count
16
105
2.56
1.29
24.7
11.2
e9/l
4.3
4.1
0.19
16
96
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
8
40
2.49
1.27
1.1
1.3
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
11
63
2.38
1.14
3.1
2.5
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
6
106
0.42
1.07
1.7
2.9
—
—
—
0
0
(40758558) Short blood count panel - Blood
8
42
2.35
1.02
21.5
9.5
—
—
—
0
0
(3019150) Specific gravity of Urine by Refractometry
8
47
2.05
0.92
4.8
3.5
—
1.0
—
0
6
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
0
24
0.00
0.84
0.0
1.8
—
—
—
0
0
(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma
13
88
2.04
0.84
8.4
4.6
mmol/l
1.2
1.2
0.51
13
75
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
0
27
0.00
0.83
0.0
1.9
—
—
—
0
0
(3002256) Pathology report gross observation
5
24
2.36
0.80
1.2
1.1
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
5
27
2.07
0.73
1.0
1.7
—
—
—
0
0
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
0
20
0.00
0.63
0.0
1.8
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
6
37
1.82
0.61
3.7
4.8
—
—
—
0
0
(3015736) pH of Urine
5
80
0.53
0.59
7.0
3.4
—
—
—
0
0
(3002385) Erythrocyte distribution width [Ratio]
18
153
1.70
0.43
48.4
17.6
%
15.5
14.0
1.67
18
148
(3000492) Spirometry study
0
15
0.00
0.43
0.0
1.8
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
0
15
0.00
0.43
0.0
1.7
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
0
16
0.00
0.43
0.0
3.1
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
0
17
0.00
0.42
0.0
1.6
—
—
—
0
0
(3010813) Leukocytes [#/volume] in Blood
19
205
0.65
0.42
59.1
22.2
e9/l
7.1
6.5
0.55
19
200
(3026361) Erythrocytes [#/volume] in Blood
19
205
0.65
0.42
59.1
22.2
e12/l
3.6
4.4
5.21
19
200
(3030467) Casts [#/volume] in Urine by Automated count
7
50
1.56
0.36
1.7
3.2
e6/l
0.2
0.2
—
7
38
(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma
8
61
1.46
0.33
2.8
3.6
ng/l
3333.4
2752.0
—
8
50
(3013115) Eosinophils [#/volume] in Blood
12
98
1.45
0.29
5.9
5.1
e9/l
0.2
0.2
0.12
12
90
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
10
80
1.43
0.26
2.1
1.9
pmol/l
77.6
107.2
—
5
34
(3003338) MCHC [Mass/volume]
13
150
0.71
0.25
21.3
18.7
g/l
329.2
330.1
0.15
13
150
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
0
11
0.00
0.22
0.0
1.7
—
—
—
0
0
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
0
11
0.00
0.22
0.0
2.1
—
—
—
0
0
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
0
10
0.00
0.22
0.0
1.7
—
—
—
0
0
(3023465) Gamma globulin [Mass/volume] in Serum or Plasma by Electrophoresis
0
10
0.00
0.22
0.0
1.0
—
9.7
—
0
10
(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma
0
13
0.00
0.21
0.0
1.6
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
0
14
0.00
0.20
0.0
1.5
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
(4010399)
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
(3001604) Monocytes [#/volume] in Blood
11
93
1.34
0.19
6.4
5.2
e9/l
0.8
0.6
1.62
11
82
(40768804) Tissue Pathology biopsy report
9
79
1.22
0.18
3.6
2.0
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
15
135
1.30
0.18
4.4
4.9
—
—
—
0
0
(3006315) Basophils [#/volume] in Blood
11
94
1.31
0.17
6.4
5.1
e9/l
0.0
0.0
0.14
11
84
(3019198) Lymphocytes [#/volume] in Blood
11
96
1.27
0.13
6.7
5.5
e9/l
1.7
1.8
0.03
11
88
(3022096) Basophils/100 leukocytes in Blood
10
87
1.26
0.12
6.8
4.9
%
0.4
0.7
—
10
80
(3020564) Creatinine [Moles/volume] in Serum or Plasma
19
194
0.90
0.10
46.4
18.0
umol/l
98.7
74.8
0.57
19
194
(42870588) Differential panel, method unspecified - Blood
7
66
1.09
0.09
7.0
4.5
—
—
—
0
0
(3019069) Monocytes/100 leukocytes in Blood
10
89
1.21
0.08
6.8
5.2
%
12.6
8.3
—
10
83
(3006504) Eosinophils/100 leukocytes in Blood
10
89
1.21
0.08
6.8
5.0
%
2.1
2.7
—
10
83
(3044889) 12 lead EKG panel
14
130
1.18
0.07
3.8
4.0
—
—
—
0
0
(3018010) Neutrophils/100 leukocytes in Blood
10
91
1.17
0.05
6.9
5.2
%
58.6
57.4
—
10
84
(3002030) Lymphocytes/100 leukocytes in Blood
10
92
1.15
0.04
7.0
5.3
%
22.5
27.6
—
10
84
(3009340) Metanephrine [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3050238) Crystals [Presence] in Synovial fluid by Light microscopy
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
(40768793) Breast Pathology biopsy report
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
(3019473) Protein [Mass/volume] in Cerebral spinal fluid
0
6
0.00
0.00
0.0
1.2
—
499.7
—
0
6
(3000764) Benzodiazepines [Presence] in Urine
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3023103) Potassium [Moles/volume] in Serum or Plasma
19
192
0.95
0.00
48.9
16.9
mmol/l
4.0
4.0
0.42
19
184
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
19
189
1.03
0.00
26.2
15.3
mg/l
40.3
19.4
1.44
19
146
(40761511) CBC panel - Blood by Automated count
19
192
0.95
0.00
44.5
13.7
—
—
—
0
0
(3003327) Ova and parasites identified in Stool by Light microscopy
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3019550) Sodium [Moles/volume] in Serum or Plasma
19
192
0.95
0.00
48.8
16.8
mmol/l
137.4
139.8
2.46
19
184
(3007628) Bicarbonate [Moles/volume] standard in Venous blood
0
6
0.00
0.00
0.0
2.8
—
22.8
—
0
6
(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(3028286) Albumin [Mass/volume] in Serum or Plasma by Electrophoresis
0
9
0.00
0.00
0.0
1.0
—
36.9
—
0
9
(3005033) Fetal Nuchal fold Thickness US
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(1001926) Buprenorphine [Presence] in Urine by Screen method
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3047352) Trisomy 18 risk [Likelihood] in Fetus
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(3043238) Trisomy 21 risk [Likelihood] in Fetus
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3008898) HLA-B27 [Presence]
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis
0
9
0.00
0.00
0.0
1.0
—
0.0
—
0
9
(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
3.0
—
149.2
—
0
5
(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(40766189) Gliadin peptide IgG Ab [Units/volume] in Serum by Immunoassay
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
0
9
0.00
0.00
0.0
1.8
—
—
—
0
0
(3050129) First trimester maternal screen panel - Serum or Plasma
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3016879) Cocaine [Presence] in Urine
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3029338) Protein.monoclonal band 3 [Mass/volume] in Serum or Plasma by Electrophoresis
0
9
0.00
0.00
0.0
1.0
—
0.0
—
0
9
(3000620) Complement C3 [Mass/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
1.3
—
1.1
—
0
8
(3004616) Nuclear Ab [Presence] in Serum
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3024891) Influenza virus A+B Ag [Presence] in Specimen
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3027944) Amphetamines [Presence] in Urine
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3052851) Hemolysis interference index of Serum or Plasma
0
5
0.00
0.00
0.0
3.4
—
—
—
0
0
(3025130) Human papilloma virus identified in Specimen
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
(3011288) Drugs identified in Urine by Screen method
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3017766) Complement C4 [Mass/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
1.1
—
0.2
—
0
8
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
(3009508) Creatinine [Moles/volume] in Urine
5
49
1.03
0.00
4.2
2.7
mmol/l
6.3
6.8
—
5
34
(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
(3012110) Lysozyme [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.2
—
13.2
—
0
5
(3023420) DNA double strand Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3004490) Bicarbonate [Moles/volume] standard in Capillary blood
0
9
0.00
0.00
0.0
6.6
—
25.9
—
0
9
(1002224) Polysomnography panel
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3024172) Erythropoietin (EPO) [Units/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.0
—
16.8
—
0
5
(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(3022313) Gas panel - Capillary blood
0
9
0.00
0.00
0.0
6.6
—
—
—
0
0
(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(3027008) Opiates [Presence] in Urine
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
3.4
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
6
61
0.98
0.00
4.0
2.5
—
—
—
0
0
(3028300) Cannabinoids [Presence] in Urine
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint SECONDA_SIDEROBLASTIC_ANAEM_DRUGS_TOXINS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have SECONDA_SIDEROBLASTIC_ANAEM_DRUGS_TOXINS.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: SECONDA_SIDEROBLASTIC_ANAEM_DRUGS_TOXINS – Secondary sideroblastic anaemia due to drugs and toxins

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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