Felty's syndrome: Felty syndrome (FS), also known as ''super rheumatoid'' disease, is a severe form of rheumatoid arthritis (RA), characterized by a triad of RA, splenomegaly and neutropenia, resulting in susceptibility to bacterial infections.
Seropositive rheumatoid arthritis, strict definition
DOID EFO Endpoint Browser PheWeb
RHEUMA_SEROPOS_STRICT
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditions
|
10701 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
1 out of 7 registries used, show all original rules. |
5569 |
4. Check minimum number of eventsNone |
5569 |
5. Include endpointsNone |
5569 |
6. Filter based on genotype QC (FinnGen only) |
5426 |
Control definitions (FinnGen only)
Control conditions
not RHEUMA_SEROPOS_OTH_ICD10
Extra metadata
First used in FinnGen datafreeze
DF3
Similar endpoints
↥List of similar endpoints to
Seropositive rheumatoid arthritis, strict definition
based on the number of shared cases.
Broader endpoints:
- Other/unspecified seropositive rheumatoid arthritis (ICD-10)
- Other/unspecified seropositive rheumatoid arthritis
- Seropositive rheumatoid arthritis, wide
- Seropositive rheumatoid arthritis
- Rheumatoid arthritis
Narrower endpoints:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 31325 | 21200 | 9976 |
| Only index persons | 29603 | 20324 | 9279 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.50 | 0.61 | 0.28 |
| Only index persons | 0.62 | 0.75 | 0.35 |
| Median age at first event (years) | |||
| Whole population | 59.60 | 59.01 | 60.86 |
| Only index persons | 59.06 | 58.50 | 60.29 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 5426 | 3764 | 1662 |
| Unadjusted period prevalence (%) | 1.28 | 1.48 | 0.83 |
| Median age at first event (years) | 56.76 | 55.05 | 60.62 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: RHEUMA_SEROPOS_STRICT – Seropositive rheumatoid arthritis, strict definition
GWS hits: 15
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