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Other disturbances of cerebral status of newborn

P16_OTH_DISTU_CEREBRAL_STATUS_NEWBO

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 P91
  • Cause of death: ICD-10 P91

2 out of 7 registries used, show all original rules.

44

4. Check minimum number of events

None

44

5. Include endpoints

None

44

6. Filter based on genotype QC (FinnGen only)

44

Control definitions (FinnGen only)

Control exclude
P16_OTH_DISORD_ORIGINA_PERINA_PERIOD

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
P9
Name in latin
Aliae perturbationes status cerebralis neonati

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1980 844 1132
Only index persons 857 361 496
Unadjusted period prevalence (%)
Whole population 0.03 0.02 0.03
Only index persons 0.02 0.01 0.02
Median age at first event (years)
Whole population 0.15 0.00 0.00
Only index persons 0.01 0.01 0.01

-FinnGen-

Key figures

All Female Male
Number of individuals 44 15 29
Unadjusted period prevalence (%) 0.01 0.01 0.01
Median age at first event (years) 0.00 0.00 0.00

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3009466) Valproate [Moles/volume] in Serum or Plasma
10
7
17.93
6.77
5.1
4.1
umol/l
455.5
437.9
—
10
7
(3022670) pH of Venous cord blood
6
9
7.50
2.97
1.0
1.0
—
—
—
0
0
(40758558) Short blood count panel - Blood
26
173
2.23
1.76
3.3
9.9
—
—
—
0
0
(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma
26
173
2.23
1.76
8.0
6.3
u/l
173.4
177.7
0.08
26
162
(3013115) Eosinophils [#/volume] in Blood
34
259
2.38
1.58
5.5
12.3
e9/l
0.3
0.2
0.57
26
211
(3000991) Gas panel - Venous blood
20
125
2.10
1.53
8.4
14.1
—
—
—
0
0
(3033658) Prothrombin time (PT) actual/Normal
17
101
2.11
1.47
5.1
11.5
%
74.4
82.0
0.83
17
101
(3012544) pH of Venous blood
20
127
2.05
1.46
6.2
12.6
—
—
—
0
0
(3023024) Carbon dioxide [Partial pressure] in Capillary blood
22
147
1.99
1.38
25.2
11.5
kpa
4.7
4.9
1.40
22
139
(3006315) Basophils [#/volume] in Blood
33
255
2.18
1.38
5.4
11.1
e9/l
0.0
0.0
0.01
24
203
(3001604) Monocytes [#/volume] in Blood
33
256
2.16
1.35
5.4
11.1
e9/l
0.7
0.6
0.07
24
204
(3013650) Neutrophils [#/volume] in Blood by Automated count
34
267
2.20
1.34
6.8
12.7
e9/l
3.0
3.4
0.51
28
219
(3014007) Fractional oxyhemoglobin in Arterial blood
5
19
2.83
1.25
8.8
37.2
%
96.5
96.9
—
5
19
(3019198) Lymphocytes [#/volume] in Blood
33
261
2.06
1.21
5.3
11.2
e9/l
3.2
2.8
0.55
25
215
(3006217) Methemoglobin/Hemoglobin.total in Arterial blood
5
20
2.68
1.18
8.8
35.4
%
0.7
0.7
—
5
20
(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood
5
20
2.68
1.18
8.8
35.4
%
1.2
1.1
—
5
20
(3035637) Corticotropin [Mass/volume] in Plasma
7
31
2.49
1.16
2.4
2.0
—
—
—
0
0
(3022313) Gas panel - Capillary blood
20
136
1.86
1.14
23.0
10.5
—
—
—
0
0
(42870588) Differential panel, method unspecified - Blood
28
212
1.88
1.14
4.0
11.6
—
—
—
0
0
(3014218) Bicarbonate [Moles/volume] standard in Arterial blood
5
21
2.55
1.12
8.0
32.5
mmol/l
22.4
23.8
—
5
21
(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma
20
137
1.84
1.11
6.3
5.0
nmol/l
79.0
71.1
0.72
20
127
(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
5
22
2.43
1.06
1.4
2.2
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
15
100
1.76
0.88
2.3
4.0
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
19
136
1.70
0.87
7.9
6.6
—
—
—
0
0
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
14
92
1.77
0.85
4.9
6.1
e6/l
0.5
1.3
—
8
62
(3011397) Hemoglobin [Presence] in Urine by Test strip
15
101
1.74
0.84
5.0
4.2
—
—
—
0
0
(3017446) Testosterone [Moles/volume] in Serum or Plasma
0
24
0.00
0.82
0.0
2.3
—
11.2
—
0
16
(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection
0
24
0.00
0.82
0.0
2.1
—
—
—
0
0
(3027008) Opiates [Presence] in Urine
5
24
2.22
0.77
1.0
1.7
—
—
—
0
0
(3000764) Benzodiazepines [Presence] in Urine
5
24
2.22
0.77
1.0
1.7
—
—
—
0
0
(3027944) Amphetamines [Presence] in Urine
5
24
2.22
0.77
1.0
1.7
—
—
—
0
0
(3016879) Cocaine [Presence] in Urine
5
24
2.22
0.77
1.0
1.7
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
13
182
0.59
0.76
1.8
2.0
—
—
—
0
0
(3028300) Cannabinoids [Presence] in Urine
5
25
2.12
0.75
1.0
1.7
—
—
—
0
0
(3028626) Oxygen [Partial pressure] in Capillary blood
19
142
1.59
0.71
27.5
10.7
kpa
9.5
9.7
0.25
19
134
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
7
44
1.70
0.69
4.7
2.3
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
32
360
0.59
0.69
4.1
4.1
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
10
64
1.73
0.65
4.3
3.3
—
—
—
0
0
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
13
90
1.63
0.65
4.7
5.7
e6/l
0.1
0.5
—
7
60
(3005719) IgG [Mass/volume] in Serum or Plasma
8
53
1.62
0.63
1.6
5.5
g/l
9.7
7.7
—
8
53
(3021589) Normoblasts [#/volume] in Blood
30
255
1.55
0.60
5.2
12.6
e9/l
0.0
0.0
0.00
20
186
(3047007) Chlamydophila sp Ab [Presence] in Serum
0
23
0.00
0.60
0.0
1.3
—
—
—
0
0
(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma
9
60
1.63
0.59
4.9
2.6
u/l
739.6
756.9
—
9
60
(3002582) Erythrocytes [#/volume] in Urine
17
130
1.50
0.55
8.4
6.5
e6/l
5.8
511.2
0.53
12
102
(3023103) Potassium [Moles/volume] in Serum or Plasma
35
311
1.61
0.53
28.4
18.8
mmol/l
4.0
4.1
0.28
35
300
(3019550) Sodium [Moles/volume] in Serum or Plasma
35
311
1.61
0.53
28.9
18.9
mmol/l
139.0
139.1
0.05
35
304
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
7
45
1.66
0.52
4.9
2.3
—
—
—
0
0
(3030467) Casts [#/volume] in Urine by Automated count
16
123
1.47
0.50
5.7
6.4
e6/l
0.0
0.5
1.26
11
96
(3037467) Urinalysis macro (dipstick) panel - Urine
25
211
1.43
0.47
8.1
5.2
—
—
—
0
0
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
15
115
1.46
0.47
11.5
6.2
ml/min/173m2
116.8
107.0
—
9
68
(3023368) Bacteria identified in Blood by Culture
10
70
1.55
0.46
4.6
4.4
—
—
—
0
0
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
19
154
1.41
0.44
28.6
15.5
mmol/l
24.5
24.4
0.04
19
154
(3030366) Cystatin C [Mass/volume] in Serum or Plasma
8
59
1.43
0.44
21.6
24.2
mg/l
1.2
1.1
—
8
59
(36304419) Bacteria [Presence] in Urine
16
126
1.42
0.43
5.9
6.1
—
—
—
0
0
(3015736) pH of Urine
15
117
1.43
0.43
8.3
4.1
—
—
—
0
0
(3011648) Oxygen content in Venous blood
0
16
0.00
0.42
0.0
25.6
—
11.9
—
0
16
(3023511) Choriogonadotropin [Units/volume] in Urine
0
16
0.00
0.42
0.0
1.3
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
5
34
1.53
0.42
1.8
1.6
—
—
—
0
0
(3021387) Prolactin [Units/volume] in Serum or Plasma
0
17
0.00
0.41
0.0
1.5
—
455.8
—
0
17
(3050129) First trimester maternal screen panel - Serum or Plasma
0
17
0.00
0.41
0.0
1.5
—
—
—
0
0
(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum
0
18
0.00
0.41
0.0
1.3
—
—
—
0
0
(3013826) Glucose [Moles/volume] in Serum or Plasma
25
215
1.38
0.40
10.8
12.5
mmol/l
5.5
5.8
0.37
25
202
(3028026) IgM [Mass/volume] in Serum or Plasma
6
42
1.49
0.37
1.3
2.9
g/l
0.9
1.1
—
6
42
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
18
149
1.35
0.36
3.7
3.2
mmol/l
1.1
1.1
0.08
18
140
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
7
52
1.41
0.33
4.9
2.4
—
—
—
0
0
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
15
124
1.32
0.29
1.6
2.3
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
5
72
0.66
0.29
1.8
1.8
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
6
84
0.67
0.27
1.2
1.3
—
—
—
0
0
(3014326) Insulin-like growth factor-I [Moles/volume] in Serum or Plasma
5
39
1.32
0.24
7.0
4.2
nmol/l
13.8
19.9
—
5
39
(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
(3005715) Vancomycin [Mass/volume] in Serum or Plasma
0
11
0.00
0.21
0.0
6.4
—
10.3
—
0
11
(40758895) Direct antiglobulin test.complement C3d specific reagent [Presence] on Red Blood Cells
0
10
0.00
0.21
0.0
3.2
—
—
—
0
0
(3008757) Leukocyte morphology finding [Identifier] in Blood
0
10
0.00
0.21
0.0
7.9
—
—
—
0
0
(40758897) Direct antiglobulin test.IgG specific reagent [Presence] on Red Blood Cells
0
10
0.00
0.21
0.0
3.2
—
—
—
0
0
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
(3000093) Morphology [Interpretation] in Blood Narrative
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
(3009445) Proteinase 3 Ab [Units/volume] in Serum
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
(3022145) Colonoscopy Study observation
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
(3003284) Neutrophil cytoplasmic Ab.perinuclear [Titer] in Serum by Immunofluorescence
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
(3016018) Differential panel - Cerebral spinal fluid
0
13
0.00
0.21
0.0
6.4
—
—
—
0
0
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
0
13
0.00
0.21
0.0
1.8
—
—
—
0
0
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
18
158
1.24
0.21
4.8
3.5
mmol/l
4.1
4.1
0.12
18
152
(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture
0
14
0.00
0.20
0.0
1.6
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
11
92
1.26
0.18
2.6
3.7
—
—
—
0
0
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
37
355
1.27
0.16
22.5
13.2
mg/l
26.9
22.8
0.29
29
233
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
17
152
1.19
0.15
5.1
3.4
mmol/l
2.5
2.4
0.20
17
143
(3018095) Leukocytes [#/volume] in Urine
17
152
1.19
0.15
12.2
7.7
e6/l
27.9
30.7
0.05
12
104
(40761511) CBC panel - Blood by Automated count
35
334
1.23
0.15
15.1
9.2
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
13
115
1.19
0.12
3.0
5.0
—
—
—
0
0
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
17
156
1.15
0.10
4.9
3.2
mmol/l
1.3
1.4
0.61
17
148
(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma
32
307
1.16
0.09
13.4
10.5
u/l
48.2
26.7
0.50
32
297
(40760892) CBC W Ordered Manual Differential panel - Blood
6
57
1.06
0.09
8.7
5.2
—
—
—
0
0
(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method
6
57
1.06
0.09
2.3
9.5
%
62.8
82.4
—
6
57
(3018677) aPTT in Platelet poor plasma by Coagulation assay
8
75
1.08
0.08
2.9
7.7
s
35.4
31.8
—
8
75
(3007164) IgA [Mass/volume] in Serum or Plasma
19
182
1.08
0.03
1.3
2.0
g/l
1.8
1.3
—
9
82
(3044889) 12 lead EKG panel
10
107
0.92
0.02
1.4
2.2
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
12
115
1.06
0.00
1.2
1.8
—
—
—
0
0
(3006598) pH of Arterial cord blood
6
60
1.00
0.00
1.0
1.0
—
—
—
0
0
(21494429) FMR1 gene CGG repeat analysis in Blood or Tissue by Molecular genetics method
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3024471) HLA-A [Type]
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3024932) HLA-DR beta [Type]
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3016031) Almond IgE Ab [Units/volume] in Serum
0
8
0.00
0.00
0.0
1.1
—
2.7
—
0
8
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
3.0
—
—
—
0
0
(3007847) Interleukin 2 Receptor Soluble [Units/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.8
—
1096.8
—
0
5
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
0
8
0.00
0.00
0.0
2.8
—
—
—
0
0
(3028369) Herpes simplex virus 1+2 DNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
2.5
—
—
—
0
0
(3046896) Herpes virus 6 DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
(42870560) Thyrotropin [Units/volume] in Cord blood
7
68
1.03
0.00
1.0
1.0
mu/l
16.1
8.7
—
7
61
(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
8
88
0.89
0.00
10.6
3.5
—
—
—
0
0
(3029715) Chromosome analysis.interphase [Interpretation] in Bone marrow by FISH Narrative
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3032352) Blasts [#/volume] in Cerebral spinal fluid
0
5
0.00
0.00
0.0
13.4
—
—
—
0
0
(3028433) Virus identified in Specimen by Culture
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3037677) Mycoplasma pneumoniae IgM Ab [Titer] in Cerebral spinal fluid
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3042299) inFLIXimab [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
14.8
—
9.2
—
0
5
(1175556) inFLIXimab Ab [Units/volume] in Serum by Immunoassay
0
5
0.00
0.00
0.0
10.6
—
—
—
0
0
(44813793)
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3002621) Streptococcal DNAse B [Units/volume] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3044212) Herpes simplex virus 1+2 IgM Ab [Presence] in Cerebral spinal fluid
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
6
62
0.96
0.00
11.3
3.1
—
—
—
0
0
(3041082) Glomerular basement membrane Ab [Titer] in Serum by Immunofluorescence
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3017115) Methotrexate [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
37.6
—
0.7
—
0
5
(3045142) Bone marrow Pathology biopsy report
0
6
0.00
0.00
0.0
2.3
—
—
—
0
0
(3007798) IgG/Albumin [Mass Ratio] in Cerebral spinal fluid
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3013247) Albumin in CSF/Albumin in Serum or Plasma
0
6
0.00
0.00
0.0
1.0
—
2.6
—
0
6
(3023530) 17-Hydroxyprogesterone [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
3.2
—
0.5
—
0
5
(42868421) Varicella zoster virus IgM Ab [Presence] in Cerebral spinal fluid by Immunoassay
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3042975) Streptococcus sp identified in Isolate by Organism specific culture
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3002823) Mycoplasma pneumoniae IgG Ab [Units/volume] in Cerebral spinal fluid
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(40761849) Varicella zoster virus IgG Ab [Units/volume] in Cerebral spinal fluid by Immunoassay
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(40760109) Toxoplasma gondii IgG Ab avidity [Ratio] in Serum by Immunoassay
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3035320) C reactive protein [Mass/volume] in Body fluid
0
8
0.00
0.00
0.0
2.0
—
—
—
0
0
(3022411) Androstenedione [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
3.4
—
2.2
—
0
5
(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(40762485) Glomerular basement membrane Ab [Units/volume] in Serum by Immunoassay
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3040893) Potassium [Moles/volume] in Capillary blood
0
6
0.00
0.00
0.0
2.2
—
4.1
—
0
6
(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(4027681)
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
3.6
—
22.2
—
0
5
(3007302) Hemoglobin [Mass/volume] in Mixed venous blood
0
8
0.00
0.00
0.0
2.6
—
—
—
0
0
(3035999) Lactate [Moles/volume] in Cerebral spinal fluid
0
5
0.00
0.00
0.0
2.2
—
1.4
—
0
5
(3018921) Toxoplasma gondii IgA Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3032080) INR in Blood by Coagulation assay
7
76
0.91
0.00
2.3
5.3
—
1.4
—
0
11
(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3024474) Albumin [Mass/volume] in Cerebral spinal fluid
0
6
0.00
0.00
0.0
1.0
—
95.5
—
0
6
(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method
0
8
0.00
0.00
0.0
1.9
—
—
—
0
0
(21494755) Public health laboratory ask at order entry panel
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
(3015916) Alpha-1-Fetoprotein [Units/volume] in Serum or Plasma
0
9
0.00
-0.00
0.0
7.2
—
42.9
—
0
9
(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma
0
9
0.00
-0.00
0.0
2.1
—
—
—
0
0
(3021513) Carbon dioxide [Partial pressure] in Mixed venous blood
0
9
0.00
-0.00
0.0
2.4
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
(3038071) Oxygen [Partial pressure] in Mixed venous blood
0
9
0.00
-0.00
0.0
2.4
—
—
—
0
0
(3008733) Herpes simplex virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
(40768443) Skin Pathology biopsy report
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint P16_OTH_DISTU_CEREBRAL_STATUS_NEWBO and mortality.

Females

Parameter HR [95% CI] p-value
P16_OTH_DISTU_CEREBRAL_STATUS_NEWBO 8.612 [3.55, 20.9] < 0.001
Birth year 0.991 [0.98, 1.0] 0.042

During the follow-up period (1.1.1998 — 31.12.2019), 54 out of 695 females with P16_OTH_DISTU_CEREBRAL_STATUS_NEWBO died.

Males

Parameter HR [95% CI] p-value
P16_OTH_DISTU_CEREBRAL_STATUS_NEWBO 11.971 [4.15, 34.5] < 0.001
Birth year 0.989 [0.98, 1.0] 0.022

During the follow-up period (1.1.1998 — 31.12.2019), 64 out of 949 males with P16_OTH_DISTU_CEREBRAL_STATUS_NEWBO died.

Mortality risk

Mortality risk for people of age

years, who have P16_OTH_DISTU_CEREBRAL_STATUS_NEWBO.

N-year risk Females Males
1 0.702% 2.331%
5 4.077% 12.945%
10 9.595% 29.693%
15 18.288% 51.317%
20 29.999% 72.107%

Relationships between endpoints

Index endpoint: P16_OTH_DISTU_CEREBRAL_STATUS_NEWBO – Other disturbances of cerebral status of newborn

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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