info icon

Dysplastic lesion of the vagina of unknown severity

N14_VAGINAL_DYSPLASIA_NOS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

only females

293373

2. Check conditions

None

293373

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 N89.3
  • Cause of death: ICD-10 N89.3

2 out of 7 registries used, show all original rules.

38

4. Check minimum number of events

None

38

5. Include endpoints

None

38

6. Filter based on genotype QC (FinnGen only)

38

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF7

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 209 209 -
Only index persons 204 204 -
Unadjusted period prevalence (%)
Whole population 0.01 0.01 -
Only index persons 0.01 0.01 -
Median age at first event (years)
Whole population - 56.19 -
Only index persons - 55.04 -

-FinnGen-

Key figures

All Female Male
Number of individuals 38 38 -
Unadjusted period prevalence (%) 0.01 0.01 -
Median age at first event (years) 53.42 53.42 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
5
15
3.67
1.57
1.2
1.1
—
—
—
0
0
(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection
6
23
2.90
1.43
3.3
1.1
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
7
31
2.53
1.18
1.3
1.6
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
14
87
1.96
1.06
2.4
1.3
—
—
—
0
0
(3000067) Parathyrin.intact [Mass/volume] in Serum or Plasma
0
30
0.00
1.02
0.0
4.0
—
87.9
—
0
25
(3023368) Bacteria identified in Blood by Culture
13
84
1.83
0.86
3.2
4.0
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
6
32
2.03
0.86
1.2
1.6
—
—
—
0
0
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
5
25
2.15
0.76
1.0
1.3
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
8
48
1.84
0.68
1.3
1.9
—
—
—
0
0
(40768443) Skin Pathology biopsy report
0
19
0.00
0.62
0.0
1.4
—
—
—
0
0
(3025839) Triglyceride [Moles/volume] in Serum or Plasma
7
107
0.58
0.60
2.3
1.7
mmol/l
1.2
1.3
—
7
92
(3003785) Carcinoembryonic Ag [Mass/volume] in Serum or Plasma
6
39
1.64
0.56
2.0
4.1
ug/l
3.8
5.8
—
6
33
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
16
122
1.54
0.55
2.5
3.6
ng/l
87.3
27.9
—
7
78
(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma
5
83
0.54
0.53
5.8
2.9
ng/l
978.2
680.0
—
5
72
(3048689) Calprotectin [Mass/mass] in Stool
7
47
1.60
0.51
2.9
2.3
ug/g
528.6
188.3
—
7
38
(40763571) Iron/Transferrin [Ratio] in Serum or Plasma
7
50
1.49
0.48
2.1
2.7
%
34.2
22.7
—
7
41
(40768804) Tissue Pathology biopsy report
19
154
1.47
0.47
2.1
2.1
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
10
71
1.55
0.45
1.8
1.4
—
—
—
0
0
(21494755) Public health laboratory ask at order entry panel
5
33
1.59
0.43
1.0
1.3
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
9
67
1.45
0.42
2.4
2.0
—
—
—
0
0
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
0
15
0.00
0.42
0.0
2.4
—
—
—
0
0
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
0
15
0.00
0.42
0.0
2.3
—
—
—
0
0
(3019225) pH of Specimen
5
34
1.54
0.42
2.0
3.9
—
—
—
0
0
(3008898) HLA-B27 [Presence]
0
18
0.00
0.41
0.0
1.1
—
—
—
0
0
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
0
18
0.00
0.41
0.0
1.3
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
6
89
0.61
0.38
1.2
1.3
—
—
—
0
0
(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma
14
111
1.41
0.37
2.8
3.4
u/l
23.5
29.2
0.97
14
106
(46235355) HIV 1 and 2 tests - Meaningful Use set
6
44
1.43
0.36
1.7
1.5
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
18
153
1.34
0.30
3.3
3.8
—
—
—
0
0
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
30
314
0.79
0.29
11.3
12.9
ml/min/173m2
83.1
80.8
0.27
23
247
(3011397) Hemoglobin [Presence] in Urine by Test strip
6
79
0.71
0.27
3.2
3.6
—
—
—
0
0
(3026493) Urate [Moles/volume] in Serum or Plasma
6
84
0.66
0.27
3.7
3.1
umol/l
313.7
6687.5
—
6
71
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
29
268
1.35
0.24
4.7
4.7
pmol/l
15.1
14.7
0.48
29
240
(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma
9
109
0.77
0.24
1.7
1.9
u/l
194.7
135.8
—
9
104
(3007853) Bacteria identified in Skin by Aerobe culture
5
39
1.32
0.24
1.4
1.5
—
—
—
0
0
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
5
40
1.29
0.23
1.2
5.2
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
12
99
1.31
0.23
2.4
1.9
—
—
—
0
0
(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells
0
11
0.00
0.22
0.0
2.4
—
—
—
0
0
(3034770) Mitochondria Ab [Titer] in Serum
0
11
0.00
0.22
0.0
1.1
—
—
—
0
0
(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection
0
11
0.00
0.22
0.0
1.5
—
—
—
0
0
(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay
0
11
0.00
0.22
0.0
1.4
—
—
—
0
0
(42529406) Shigella sp [Presence] in Stool by Culture
0
10
0.00
0.22
0.0
1.5
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
6
48
1.30
0.21
2.2
1.8
—
—
—
0
0
(3043109) Cytology report of Tissue fine needle aspirate Cyto stain
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
(3023150) Myeloperoxidase Ab [Units/volume] in Serum
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
(4034850)
0
13
0.00
0.21
0.0
6.8
—
—
—
0
0
(3017766) Complement C4 [Mass/volume] in Serum or Plasma
0
13
0.00
0.21
0.0
1.1
—
0.2
—
0
13
(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma
7
84
0.80
0.16
3.4
1.9
mg/l
2.1
3.3
—
7
74
(3031040) Bacteria [#/volume] in Urine by Automated count
21
228
0.82
0.16
6.1
4.9
—
549.7
—
0
7
(3037467) Urinalysis macro (dipstick) panel - Urine
21
227
0.83
0.14
5.7
4.4
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
11
125
0.83
0.12
6.6
4.1
—
—
—
0
0
(3000850) Epithelial cells [#/volume] in Urine
6
70
0.83
0.08
3.0
3.1
e6/l
7.3
5.2
—
6
61
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
15
138
1.14
0.08
2.3
1.9
pmol/l
75.5
103.8
—
6
70
(3041096) Erythrocytes [Presence] in Urine by Automated
9
86
1.06
0.08
6.7
3.8
—
—
—
0
0
(3013512) EKG study
9
101
0.86
0.07
3.4
3.5
—
—
—
0
0
(3003338) MCHC [Mass/volume]
29
282
1.12
0.07
15.4
18.0
g/l
331.0
330.0
0.27
29
282
(3026008) Bacteria identified in Urine by Culture
10
110
0.88
0.06
6.9
3.1
—
—
—
0
0
(3001122) Ferritin [Mass/volume] in Serum or Plasma
16
150
1.12
0.05
4.2
3.1
ug/l
139.2
80.8
0.37
16
139
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
11
119
0.89
0.04
3.2
3.0
—
—
—
0
0
(40758558) Short blood count panel - Blood
11
102
1.11
0.03
2.6
7.5
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
23
236
0.94
0.01
3.6
2.9
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
11
111
0.99
0.00
2.7
2.7
—
—
—
0
0
(42870588) Differential panel, method unspecified - Blood
11
109
1.01
0.00
6.0
5.6
—
—
—
0
0
(3015736) pH of Urine
13
135
0.94
0.00
4.6
3.8
—
—
—
0
0
(3044889) 12 lead EKG panel
23
233
0.97
0.00
3.7
3.6
—
—
—
0
0
(3002523) Influenza virus A Ag [Presence] in Specimen
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3003740) Influenza virus B Ag [Presence] in Specimen
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3012110) Lysozyme [Mass/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.3
—
10.4
—
0
6
(3004616) Nuclear Ab [Presence] in Serum
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3019250) Coagulation factor VIII activity actual/normal in Platelet poor plasma by Coagulation assay
0
6
0.00
0.00
0.0
2.0
—
133.0
—
0
6
(3011288) Drugs identified in Urine by Screen method
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(4281824)
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(4306422)
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(4146454)
0
6
0.00
0.00
0.0
4.0
—
—
—
0
0
(3004809) Band form neutrophils/100 leukocytes in Blood
0
6
0.00
0.00
0.0
6.7
—
2.8
—
0
6
(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method
0
6
0.00
0.00
0.0
1.8
—
108.8
—
0
6
(3026285) Alpha 1 antitrypsin [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.0
—
1.5
—
0
5
(3020629) Protein S Free Ag actual/normal in Platelet poor plasma by Immunoassay
0
5
0.00
0.00
0.0
1.0
—
101.8
—
0
5
(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(36304997) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ and CD8+ T-cells [Units/volume] in Blood
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
(3024522) Salmonella sp identified in Specimen by Organism specific culture
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(3006418) Campylobacter sp identified in Tissue by Organism specific culture
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
(3005988) Vibrio sp identified in Specimen by Organism specific culture
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3012568) Campylobacter sp identified in Specimen by Organism specific culture
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
9
96
0.92
0.00
3.4
2.8
—
—
—
0
0
(3001788) Aldosterone [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.0
—
234.8
—
0
5
(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3030905) Polymorphonuclear cells [#/volume] in Blood
0
5
0.00
0.00
0.0
2.2
—
7.6
—
0
5
(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(4094501)
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(40766800) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells [Units/volume] corrected for background in Blood
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3003434) Protein [Mass/volume] in Pleural fluid
0
5
0.00
0.00
0.0
1.2
—
24.9
—
0
5
(3023420) DNA double strand Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3025468) Yersinia sp identified in Specimen by Organism specific culture
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3028707) Methadone [Presence] in Urine by Screen method
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3014765) Yersinia sp identified in Stool by Organism specific culture
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
(3037756) Immunofixation for Serum or Plasma
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(3042111) Morphology [Interpretation] in Bone marrow Narrative
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3032035) Polymorphonuclear cells/100 leukocytes in Blood
0
5
0.00
0.00
0.0
5.2
—
68.4
—
0
5
(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(40760888) Immunoglobulin light chains.free panel - Serum
0
9
0.00
0.00
0.0
7.6
—
—
—
0
0
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
8
78
1.03
0.00
3.1
5.1
—
—
—
0
0
(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(4268621)
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3025018) Bordetella pertussis Ab [Titer] in Serum
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(40759836) Histone Ab [Presence] in Serum by Immunoblot
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(1617658) Protocol used for examination of sentinel lymph nodes
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint N14_VAGINAL_DYSPLASIA_NOS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have N14_VAGINAL_DYSPLASIA_NOS.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: N14_VAGINAL_DYSPLASIA_NOS – Dysplastic lesion of the vagina of unknown severity

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data