HSIL lesion of the vagina

N14_VAGINAL_HSIL

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule only females	293373
2. Check conditions None	293373
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — D07.2&, N89.1, N89.2 Hospital discharge: ICD-9 — 2333A\|6230B\|6230C Cause of death: ICD-10 — D07.2&, N89.1, N89.2 Cause of death: ICD-9 — 2333A\|6230B\|6230C 2 out of 7 registries used, show all original rules.	482
4. Check minimum number of events None	482
5. Include endpoints None	482
6. Filter based on genotype QC (FinnGen only)	482

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze: DF7

NAME	N14_VAGINAL_HSIL
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX	2
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	N891\|N892\|D072
HD_ICD_9	2333A\|6230B\|6230C
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	N891\|N892\|D072
COD_ICD_9	2333A\|6230B\|6230C
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to HSIL lesion of the vagina based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	2714	2714	-
Only index persons	2571	2571	-
Unadjusted period prevalence (%)
Whole population	0.08	0.08	-
Only index persons	0.09	0.09	-
Median age at first event (years)
Whole population	-	49.94	-
Only index persons	-	48.76	-

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	482	482	-
Unadjusted period prevalence (%)	0.16	0.16	-
Median age at first event (years)	49.80	49.80	-

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
427: Matched controls
4268

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

N89.1

ICD-10 Finland

Moderate vaginal dysplasia

+∞

299.5

251

LEB30

NOMESCO Finland

Destruction of lesion of vaginal mucosa

480.7

220.9

203

ULA02

NOMESCO Finland

Kolposcopy

38.4

220.8

335

369

N89.2

ICD-10 Finland

Severe vaginal dysplasia, not elsewhere classified

+∞

207.8

182

LEB00

NOMESCO Finland

Biopsy of vagina

118.1

206.3

214

R87.6

ICD-10 Finland

Abnormal findings in specimens from female genital organs, abnormal cytological findings

23.7

172.4

295

368

LDA20

NOMESCO Finland

Biopsy of vaginal cervix

18.2

123.4

213

221

8077/2-C52.9

ICD-O-3

Squamous intraepithelial neoplasia, high grade of vagina, NOS

+∞

114.9

105

XLD00

NOMESCO Finland

Sytologyspecimen from mouth of uterus

12.1

110.8

251

449

LDC03

NOMESCO Finland

Conisation of cervix uteri using diathermy or laser

14.3

75.5

137

136

N89.0

ICD-10 Finland

Mild vaginal dysplasia

131.6

72.6

N87.0

ICD-10 Finland

Mild cervical dysplasia

21.0

58.2

LDA10

NOMESCO Finland

Curettage of cervix uteri

11.5

58.1

116

134

A63.0

ICD-10 Finland

Anogenital (venereal) warts

14.9

51.5

N87.1

ICD-10 Finland

Moderate cervical dysplasia

14.7

46.7

LFB00

NOMESCO Finland

Biopsy of vulva or perineum

14.0

43.1

N87.2

ICD-10 Finland

Severe cervical dysplasia, not elsewhere classified

11.7

35.6

N90.1

ICD-10 Finland

Moderate vulvar dysplasia

122.8

32.2

LDB20

NOMESCO Finland

Electrocoagulation or laser therapy of cervix uteri

24.4

31.2

N90.2

ICD-10 Finland

Severe vulvar dysplasia, not elsewhere classified

+∞

29.5

8077/2-C53.9

ICD-O-3

Squamous intraepithelial neoplasia, high grade of cervix uteri

12.7

25.6

LEB10

NOMESCO Finland

Excision of lesion of vagina

28.7

23.9

LFB20

NOMESCO Finland

Destruction of lesion of vulva or perineum

25.4

23.8

LC2BE

NOMESCO Finland

Transvaginal ultrasound examination of uterus, parametria and lower abdomen

2.7

21.4

218

1181

ZXC10

NOMESCO Finland

Use of laser

9.9

17.5

D07.2

ICD-10 Finland

Carcinoma in situ: Vagina

+∞

16.8

N90.0

ICD-10 Finland

Mild vulvar dysplasia

62.4

15.9

LFB10

NOMESCO Finland

Excision of lesion of vulva or perineum

14.7

15.2

R87.5

ICD-10 Finland

Abnormal findings in specimens from female genital organs, abnormal microbiological findings

13.1

15.1

6230B

ICD-9 Finland

Noninflammatory disorders of vagina, Dysplasia of vagina[DYSPLASIA VAGINAE MODERATA]

+∞

13.6

8077/2-C51.9

ICD-O-3

Squamous intraepithelial neoplasia, high grade of vulva, NOS

+∞

12.6

D06BB10

ATC

imiquimod; topical

4.7

11.2

G03CA03

ATC

estradiol; nasal, systemic, rectal, transdermal, vaginal

1.9

9.3

275

2073

ZXC00

NOMESCO Finland

Use of diathermy

16.0

9.1

8325

FHL

Coagulation, cryo or laser in anesthesia or operating room

34.0

8.1

0781C

ICD-9 Finland

Other diseases due to viruses and Chlamydiae, Viral warts[CONDYLOMA ACCUMINATUM]

11.1

7.8

WZB00

NOMESCO Finland

Telephone receipt or other advice

1.9

7.5

136

851

D06BB04

ATC

podophyllotoxin; topical

3.3

7.3

111

C52.91

ICD-10 Finland

Squamous cell carcinoma of the vagina

+∞

7.3

8070/3-C52.9

ICD-O-3

Squamous cell carcinoma, NOS, of vagina, NOS

+∞

7.3

6230C

ICD-9 Finland

Noninflammatory disorders of vagina, Dysplasia of vagina[DYSPLASIA VAGINAE GRAVIS]

+∞

7.3

D07.1

ICD-10 Finland

Carcinoma in situ: Vulva

+∞

7.3

Z09.0

ICD-10 Finland

Follow-up examination after surgery for other conditions

2.4

7.0

265

8326

FHL

Batch conization

17.0

6.8

XXA00

NOMESCO Finland

Clinical examination requiring general anaesthesia

17.0

6.8

NF1AE

NOMESCO Finland

Hip joint ultrasound examination

6.1

6.7

C539, 6666, 0

ICD-O-3

5.5

6.5

R87.7

ICD-10 Finland

Abnormal findings in specimens from female genital organs, abnormal histological findings

14.6

6.4

M32.9

ICD-10 Finland

Systemic lupus erythematosus, unspecified

8.3

6.4

L04AA06

ATC

mycophenolic acid; systemic

6.1

6.4

LEC00

NOMESCO Finland

Partial excision of vagina

27.1

6.2

A12AX

ATC

Calcium, combinations with vitamin D and/or other drugs

1.7

6.1

160

1106

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

unit

cases

controls

-log₁₀(p)

N cases

N controls

(3025130) Human papilloma virus identified in Specimen

13.03

83.08

4.1

1.6

—

(40771527) Human papilloma virus E6+E7 mRNA [Presence] in Cervix by NAA with probe detection

21.82

66.86

4.7

1.5

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

280

1114

4.61

61.00

3.2

1.4

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

116

253

5.72

52.69

3.5

1.4

—

(40768804) Tissue Pathology biopsy report

285

1877

2.27

16.91

4.2

2.0

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

306

2.26

7.67

1.8

1.6

—

(4035726)

378

2.13

7.53

1.4

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

241

2.35

7.13

1.8

1.5

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

248

1928

1.59

5.85

4.0

3.9

—

(3019225) pH of Specimen

385

1.96

5.80

3.9

3.7

—

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

152

2.48

5.70

5.2

1.8

—

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

242

1881

1.58

5.65

2.9

2.3

nmol/l

80.0

78.4

0.42

223

1689

(3028167) CD3+CD4+ (T4 helper) cells [#/volume] in Blood

4.90

5.52

1.7

e6/l

805.4

913.4

—

(3045424) Erythrocytes [Presence] in Urine

3.11

5.44

1.2

1.5

—

(3012336) Haptoglobin [Mass/volume] in Serum or Plasma

128

2.52

5.16

1.7

2.4

g/l

1.5

0.07

112

(3022250) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Lactate to pyruvate reaction

349

1.93

5.11

5.9

4.1

u/l

249.1

237.4

0.30

332

(3051611) Lipemic interference index of Serum or Plasma

4.53

5.06

3.8

3.6

—

(3041067) Sjogrens syndrome-A extractable nuclear 52kD Ab [Units/volume] in Serum

3.74

4.96

1.5

1.1

u/ml

45.6

68.7

—

(3009508) Creatinine [Moles/volume] in Urine

155

1114

1.58

4.93

3.5

2.9

mmol/l

6.6

6.9

0.37

125

923

(3024561) Albumin [Mass/volume] in Serum or Plasma

211

1630

1.52

4.82

6.4

4.1

g/l

36.0

0.05

193

1515

(3021960) Folate [Moles/volume] in Serum or Plasma

130

909

1.59

4.61

1.5

nmol/l

20.7

22.2

0.49

112

770

(3013115) Eosinophils [#/volume] in Blood

262

2136

1.50

4.53

9.1

6.0

e9/l

0.2

0.27

238

1895

(3019198) Lymphocytes [#/volume] in Blood

257

2093

1.49

4.43

8.9

5.6

e9/l

1.9

2.0

0.67

236

1860

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

134

953

1.56

4.39

2.4

2.1

—

(3009261) Glucose [Presence] in Urine by Test strip

254

2083

1.46

4.11

4.5

3.6

estimate

0.0

0.80

386

(3001604) Monocytes [#/volume] in Blood

249

2038

1.46

4.04

9.0

5.6

e9/l

0.5

0.43

228

1785

(3002030) Lymphocytes/100 leukocytes in Blood

242

1970

1.46

4.04

8.6

5.8

28.5

29.0

0.33

228

1829

(3011397) Hemoglobin [Presence] in Urine by Test strip

129

925

1.54

4.04

4.8

3.6

—

(3016921) Smith extractable nuclear Ab [Units/volume] in Serum

132

2.27

3.94

1.6

1.2

u/ml

4.5

2.0

—

(3018010) Neutrophils/100 leukocytes in Blood

239

1949

1.45

3.91

8.5

5.5

56.9

56.8

0.05

227

1816

(3006315) Basophils [#/volume] in Blood

249

2050

1.44

3.85

9.1

5.6

e9/l

0.0

0.29

228

1790

(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence

3.13

3.84

1.1

—

(3012516) Albumin [Mass/volume] in Urine

139

1023

1.50

3.83

3.5

3.0

mg/l

54.6

250.3

0.87

600

(3022096) Basophils/100 leukocytes in Blood

228

1849

1.44

3.81

8.5

5.7

0.7

0.32

214

1710

(3006504) Eosinophils/100 leukocytes in Blood

235

1919

1.44

3.77

8.6

5.7

2.8

2.7

0.31

223

1776

(3006999) Ribonucleoprotein extractable nuclear Ab [Units/volume] in Serum

135

2.22

3.75

1.6

1.2

u/ml

2.7

12.5

—

(3029937) Albumin [Presence] in Urine by Test strip

146

1090

1.49

3.74

4.9

3.9

estimate

0.0

0.80

395

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

533

1.62

3.64

1.7

2.0

—

(3019309) Folate [Moles/volume] in Red Blood Cells

667

1.57

3.63

1.7

nmol/l

1147.8

1225.0

0.38

499

(3021601) Nitrite [Presence] in Urine by Test strip

249

2065

1.43

3.62

5.7

4.9

estimate

0.0

0.50

393

(3019069) Monocytes/100 leukocytes in Blood

235

1929

1.43

3.62

9.1

5.9

8.2

8.1

0.20

222

1799

(3020682) Albumin/Creatinine [Ratio] in Urine

144

1079

1.48

3.61

4.2

3.7

mg/mmol

13.1

5.5

0.62

614

(3013707) Erythrocyte sedimentation rate by Westergren method

355

3147

1.49

3.57

5.5

4.1

mm/h

13.2

11.6

1.33

329

2908

(3004616) Nuclear Ab [Presence] in Serum

2.76

3.52

1.5

1.3

—

(3021197) Magnesium Ionized [Moles/volume] in Serum or Plasma

6.24

3.51

3.6

3.2

—

(3026008) Bacteria identified in Urine by Culture

170

1325

1.44

3.44

3.5

2.9

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

549

1.59

3.43

2.2

1.8

—

(3000991) Gas panel - Venous blood

242

1.85

3.36

9.4

7.0

—

(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma

486

1.62

3.35

3.8

4.1

33.0

33.2

0.07

311

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

3.49

3.35

1.2

1.3

—

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

353

3142

1.46

3.34

10.2

7.0

u/l

74.0

76.6

0.74

342

2927

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

483

1.60

3.21

1.7

1.9

—

(3035350) Ketones [Presence] in Urine by Test strip

245

2056

1.39

3.18

4.5

3.5

estimate

0.0

0.00

394

(42870588) Differential panel, method unspecified - Blood

167

1316

1.41

3.13

8.2

5.6

—

(3037467) Urinalysis macro (dipstick) panel - Urine

322

2836

1.41

3.09

5.6

4.3

—

(3019150) Specific gravity of Urine by Refractometry

120

892

1.46

3.08

5.4

3.8

kg/l

1.0

0.69

114

(40761535) Cells panel - Urine sediment

314

1.70

2.96

5.0

3.4

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

195

1599

1.37

2.82

2.0

1.9

pmol/l

105.8

100.1

0.62

101

772

(3026389) Candida sp identified in Specimen by Organism specific culture

2.59

2.81

1.3

—

(3020779) Urea [Moles/volume] in Serum or Plasma

241

1.77

2.81

11.8

6.1

mmol/l

10.1

8.2

1.25

229

(3023520) Reticulocytes [#/volume] in Blood

241

1.77

2.81

2.9

2.7

e9/l

68.3

76.0

0.70

181

(3051651) Icteric interference index of Serum or Plasma

4.50

2.80

4.9

3.8

—

(3045414) Leukocytes [Presence] in Urine

189

1.86

2.78

1.8

—

(3007853) Bacteria identified in Skin by Aerobe culture

428

1.57

2.70

1.9

1.6

—

(3048689) Calprotectin [Mass/mass] in Stool

568

1.49

2.57

2.8

2.2

ug/g

149.3

120.3

0.24

434

(3037522) Nuclear Ab [Titer] in Serum

647

1.46

2.54

1.8

1.3

titre

747.1

563.0

0.39

147

(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells

2.31

2.54

1.8

1.7

—

(3000093) Morphology [Interpretation] in Blood Narrative

3.51

2.49

1.0

1.2

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

170

1386

1.35

2.49

3.4

3.2

ng/l

23.2

27.4

0.29

850

(3013650) Neutrophils [#/volume] in Blood by Automated count

274

2396

1.33

2.48

12.1

8.8

e9/l

3.9

0.00

251

2115

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

210

1768

1.33

2.47

7.0

4.9

mmol/l

1.2

0.17

189

1595

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

251

1.69

2.46

2.0

1.5

—

(3026493) Urate [Moles/volume] in Serum or Plasma

125

972

1.39

2.46

3.1

2.4

umol/l

315.8

7188.9

4.99

111

843

(3008757) Leukocyte morphology finding [Identifier] in Blood

2.98

2.42

2.6

3.7

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

365

1.57

2.41

2.0

1.7

—

(3000067) Parathyrin.intact [Mass/volume] in Serum or Plasma

317

1.61

2.39

4.7

2.9

ng/l

124.7

75.4

1.82

284

(21493690) Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood

3.68

2.37

1.4

1.8

—

(3044640) Blood type and Crossmatch panel - Blood

157

1274

1.34

2.35

2.5

2.2

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

479

1.49

2.28

9.0

5.6

—

(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection

4.66

2.28

1.2

1.3

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

133

1057

1.36

2.27

1.3

u/ml

1.8

2.1

0.10

291

(3027945) Reticulocytes/100 erythrocytes in Blood

339

1.56

2.23

3.9

2.7

2.0

1.9

0.42

299

(40758558) Short blood count panel - Blood

133

1061

1.35

2.21

8.9

6.6

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

365

1.54

2.20

2.1

1.8

—

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

119

935

1.36

2.18

3.1

2.9

ng/l

828.7

1029.8

0.54

780

(37020957) Sapovirus genogroups I+II+IV+V RNA [Presence] in Stool by NAA with probe detection

3.72

2.16

1.7

1.2

—

(42869457) Rotavirus RNA [Identifier] in Stool by NAA with probe detection

3.72

2.16

1.7

1.2

—

(37021247) Adenovirus 40+41 DNA [Presence] in Stool by NAA with probe detection

4.33

2.15

1.8

1.1

—

(37020445) Astrovirus RNA [Presence] in Stool by NAA with probe detection

4.33

2.15

1.8

1.1

—

(3015377) Calcium [Moles/volume] in Serum or Plasma

172

1434

1.31

2.10

3.5

3.2

mmol/l

2.4

0.62

143

1257

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

247

1.63

2.09

1.8

1.5

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

2.06

2.08

1.7

1.2

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

177

1.74

2.07

1.7

1.6

—

(40757349) CD3+CD4+ (T4 helper) cells/CD3+CD8+ (T8 suppressor cells) cells [# Ratio] in Blood

5.04

2.07

1.6

2.3

—

(3046294) Neutrophil cytoplasmic Ab.classic [Titer] in Serum

3.54

2.06

1.4

1.3

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

227

1970

1.29

2.03

8.8

5.6

mmol/l

1.2

0.06

197

1653

(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma

2.85

2.01

2.0

1.6

g/l

1.0

—

(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma

143

1171

1.31

1.97

2.0

u/l

112.2

131.6

0.79

135

1106

(3017143) Hepatitis C virus Ab [Presence] in Serum

451

1.46

1.96

1.6

1.5

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

652

1.39

1.96

1.6

—

(3002032) Base excess in Venous blood by calculation

292

1.56

1.96

6.0

2.8

mmol/l

1.3

2.4

1.56

236

(3011391) Calcitriol [Moles/volume] in Serum or Plasma

2.76

1.94

1.0

1.1

—

(3013512) EKG study

135

1101

1.31

1.91

3.7

3.4

—

(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count

3.21

1.88

1.7

3.3

—

(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma

122

983

1.32

1.88

3.1

2.2

mg/l

2.7

3.0

0.96

109

839

(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma

738

1.36

1.86

2.8

2.7

mmol/l

2.5

2.4

0.41

647

(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum

2.53

1.84

3.1

2.6

—

(3027529) Toxoplasma gondii IgM Ab [Units/volume] in Serum

2.60

1.81

1.7

1.3

—

(3023939) Sjogrens syndrome-A extractable nuclear Ab [Units/volume] in Serum

109

1.87

1.80

1.8

1.2

u/ml

51.5

26.3

—

(3000330) Specific gravity of Urine by Test strip

193

0.46

1.77

7.4

3.1

—

(3000850) Epithelial cells [#/volume] in Urine

781

1.34

1.76

2.9

2.4

e6/l

10.0

8.3

0.26

698

(3012447) Hantavirus puumala IgG Ab [Titer] in Serum

2.53

1.74

1.0

1.1

—

(3007164) IgA [Mass/volume] in Serum or Plasma

111

894

1.31

1.71

1.6

1.5

g/l

2.1

2.2

0.41

549

(1761868) Lipid panel - Serum or Plasma

132

1574

0.78

1.68

2.6

2.7

—

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

142

1.73

1.68

2.1

1.7

—

(3029023) Hepatitis E virus IgG Ab [Presence] in Serum by Immunoassay

3.18

1.66

1.0

1.1

—

(3002222) Hepatitis E virus IgM Ab [Presence] in Serum

3.18

1.66

1.0

1.1

—

(3010503) CD19 cells [#/volume] in Blood

3.18

1.66

1.5

1.9

e9/l

0.2

—

(3003396) Base excess in Arterial blood by calculation

355

1.46

1.65

6.3

6.7

mmol/l

1.0

1.5

0.51

291

(3016502) Oxygen saturation in Arterial blood

305

1.49

1.63

6.3

7.0

96.3

96.1

0.09

299

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

151

1.69

1.63

2.4

1.8

—

(3035933) Granulocytes/100 leukocytes in Blood

3.60

1.62

1.6

3.2

—

(3052851) Hemolysis interference index of Serum or Plasma

106

1.82

1.61

4.7

3.3

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

603

1.35

1.58

3.8

2.4

e6/l

1.3

0.01

308

(3006922) Hepatitis E virus Ab [Presence] in Serum

3.02

1.58

1.0

1.1

—

(3014037) CD3+CD4+ (T4 helper) cells/100 cells in Blood

3.02

1.58

2.0

2.6

—

54.0

—

(3014148) Varicella zoster virus Ab [Titer] in Serum

2.23

1.58

1.3

1.2

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

2.23

1.58

1.1

1.2

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

293

1.47

1.52

1.6

1.3

—

(3002256) Pathology report gross observation

554

1.35

1.51

1.4

1.2

—

(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection

2.52

1.45

2.4

1.8

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

775

1.30

1.45

1.8

1.7

—

(3030366) Cystatin C [Mass/volume] in Serum or Plasma

1.82

1.45

3.1

2.3

mg/l

2.0

1.4

1.06

(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)

339

1.43

1.44

2.3

2.4

ml/min/173m2

69.9

69.8

0.00

135

(3047007) Chlamydophila sp Ab [Presence] in Serum

2.00

1.44

1.1

1.2

—

(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay

119

1.71

1.40

1.0

1.1

—

(3013826) Glucose [Moles/volume] in Serum or Plasma

246

2219

1.22

1.39

5.3

4.1

mmol/l

6.5

0.16

235

2056

(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence

2.43

1.39

1.6

1.2

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

433

4166

1.39

1.37

17.5

12.2

mg/l

16.5

20.0

2.03

339

3205

(3015736) pH of Urine

185

1623

1.23

1.37

4.5

3.3

—

(36304997) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ and CD8+ T-cells [Units/volume] in Blood

136

1.65

1.35

1.6

iu/ml

0.0

0.1

—

(44816844) Macroprolactin [Units/volume] in Serum or Plasma

2.15

1.34

1.2

—

(3023368) Bacteria identified in Blood by Culture

106

877

1.27

1.33

5.2

3.8

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

115

962

1.26

1.31

1.7

1.6

mg/l

1.0

0.9

0.28

735

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

182

1602

1.22

1.29

4.8

3.6

—

(3017732) Neutrophils [#/volume] in Blood

278

1.44

1.29

3.4

3.0

e9/l

4.6

4.2

0.39

225

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

122

1.67

1.29

1.2

1.3

—

(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay

2.02

1.28

1.1

—

(3000494) Fungus identified in Specimen by Culture

490

1.33

1.25

1.3

—

(3014765) Yersinia sp identified in Stool by Organism specific culture

139

1.61

1.25

1.4

1.2

—

(3006418) Campylobacter sp identified in Tissue by Organism specific culture

139

1.61

1.25

1.4

1.2

—

(3019550) Sodium [Moles/volume] in Serum or Plasma

436

4210

1.37

1.25

17.3

13.2

mmol/l

139.7

0.29

429

4092

(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma

820

1.26

1.23

1.5

1.6

pmol/l

50549872.6

30205732.3

0.15

682

(36660697) Celiac disease serology panel - Serum

359

1.37

1.23

1.2

—

(36304419) Bacteria [Presence] in Urine

120

1018

1.24

1.21

3.8

2.7

—

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

1.85

1.20

1.3

1.2

—

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

1.85

1.20

1.3

1.2

—

(42529406) Shigella sp [Presence] in Stool by Culture

141

1.59

1.19

1.4

1.2

—

(3020891) Body temperature

118

1.64

1.16

4.9

4.4

—

(4027681)

0.00

1.16

0.0

1.1

—

(40768443) Skin Pathology biopsy report

183

1.50

1.16

1.5

1.2

—

(44790049)

2.07

1.15

1.6

—

(44790048)

2.07

1.15

1.6

—

(44790047)

2.07

1.15

1.6

—

(44806118)

2.07

1.15

1.6

—

(3023103) Potassium [Moles/volume] in Serum or Plasma

436

4219

1.35

1.14

17.6

13.2

mmol/l

3.9

0.36

427

4088

(3009991) Angiotensin converting enzyme [Enzymatic activity/volume] in Cerebral spinal fluid

0.00

1.14

0.0

1.1

—

1.1

—

(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma

1.87

1.14

1.8

1.4

—

(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum

2.02

1.12

1.1

—

(3022217) INR in Platelet poor plasma by Coagulation assay

401

1.33

1.11

28.1

19.2

inr

1.2

0.09

(3020564) Creatinine [Moles/volume] in Serum or Plasma

451

4391

1.42

1.10

18.7

13.8

umol/l

72.0

68.2

1.18

451

4391

(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma

2.40

1.09

1.0

1.3

ug/l

127.7

30.7

—

(3007821) Glucose [Moles/volume] in Serum or Plasma --baseline

2.40

1.09

1.2

1.4

mmol/l

5.3

5.4

—

(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay

2.40

1.09

1.0

1.2

—

(3002582) Erythrocytes [#/volume] in Urine

129

1115

1.21

1.08

4.3

2.9

e6/l

23.5

46.1

1.19

101

832

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

2.20

1.08

2.7

1.4

—

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

2.20

1.08

2.4

1.7

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

2.20

1.08

2.7

1.4

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

2.20

1.08

2.7

1.4

—

(4034850)

121

1.59

1.07

8.1

6.6

—

(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay

2.14

1.06

1.0

—

(3034780) Angiotensin converting enzyme [Enzymatic activity/volume] in Serum or Plasma

179

1.48

1.05

1.7

2.3

u/l

40.0

39.5

0.04

162

(3030467) Casts [#/volume] in Urine by Automated count

119

1024

1.22

1.05

4.2

2.8

e6/l

0.3

0.4

0.30

753

(3004789) Transferrin [Mass/volume] in Serum or Plasma

532

1.28

1.03

4.2

2.1

g/l

2.3

2.4

1.73

487

(3013327) Hepatitis A virus IgM Ab [Presence] in Serum

1.85

1.03

1.0

1.1

—

(3017181) Myelocytes/100 leukocytes in Blood

335

1.34

1.03

4.9

4.0

0.8

0.02

(3042111) Morphology [Interpretation] in Bone marrow Narrative

1.89

1.01

2.8

1.4

—

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

148

1.51

1.00

3.3

2.1

0.6

0.7

0.97

143

(3043109) Cytology report of Tissue fine needle aspirate Cyto stain

124

1.55

0.98

1.3

1.2

—

(3025159) Blasts/100 leukocytes in Blood

303

1.35

0.97

5.0

4.1

0.0

1.4

0.54

(46235128) Lupus anticoagulant aPTT and dRVVT screening panel W Reflex

0.00

0.96

0.0

1.2

—

(3022313) Gas panel - Capillary blood

133

1.53

0.96

4.0

3.3

—

(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma

452

4414

1.39

0.95

13.3

9.8

u/l

23.0

23.5

0.37

437

4263

(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma

1.74

0.93

1.1

1.2

—

(3018095) Leukocytes [#/volume] in Urine

155

1382

1.18

0.92

4.8

3.4

e6/l

50.7

87.2

0.87

108

923

(3035320) C reactive protein [Mass/volume] in Body fluid

2.16

0.92

2.8

2.0

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

254

1.36

0.91

1.1

1.0

—

(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay

1.76

0.90

1.1

1.0

—

(3022145) Colonoscopy Study observation

479

1.26

0.89

1.5

1.3

—

(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection

1.80

0.88

1.7

1.3

—

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

153

1.46

0.87

3.3

2.1

1.4

1.1

0.34

153

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

1.74

0.87

2.5

1.9

—

(3022948) Iron [Moles/volume] in Serum or Plasma

573

1.24

0.86

4.2

2.2

umol/l

12.9

13.3

0.21

521

(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay

1.68

0.86

2.5

2.7

u/ml

0.2

0.4

—

(3021440) Promyelocytes/100 leukocytes in Blood

319

1.31

0.85

5.0

4.1

0.1

0.20

(3023421) Hepatitis B virus surface Ab [Units/volume] in Serum

171

1.42

0.85

1.3

miu/ml

213.3

246.0

0.18

(3053028) Streptococcus sp identified in Specimen by Organism specific culture

1.95

0.84

1.2

1.4

—

(3005988) Vibrio sp identified in Specimen by Organism specific culture

1.77

0.84

1.7

1.3

—

(3025468) Yersinia sp identified in Specimen by Organism specific culture

1.77

0.84

1.7

1.3

—

(3019230) Fractional oxyhemoglobin in Venous blood

1.71

0.81

1.1

1.6

52.6

58.7

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

1.57

0.79

3.4

2.4

—

(40763571) Iron/Transferrin [Ratio] in Serum or Plasma

487

1.24

0.79

4.3

2.2

24.5

22.3

0.64

411

(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.78

0.0

1.5

—

(3045142) Bone marrow Pathology biopsy report

1.77

0.76

1.0

1.2

—

(3042936) Bacteria identified in Isolate by Culture

526

1.23

0.76

2.2

1.9

—

(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma

226

2099

1.14

0.76

8.1

5.5

umol/l

9.2

9.6

0.42

218

1975

(3024522) Salmonella sp identified in Specimen by Organism specific culture

1.71

0.76

1.7

1.3

—

(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection

1.71

0.76

1.7

1.3

—

(3012568) Campylobacter sp identified in Specimen by Organism specific culture

1.71

0.76

1.7

1.3

—

(3024928) Oxygen saturation in Venous blood

1.66

0.75

1.5

2.2

—

(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma

263

1.31

0.75

2.6

2.4

ug/l

2.3

4.7

2.38

235

(3028707) Methadone [Presence] in Urine by Screen method

1.62

0.75

3.9

1.4

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

555

1.22

0.75

4.4

2.5

e6/l

3.1

4.8

0.95

264

(3005082) Progesterone [Moles/volume] in Serum or Plasma

2.09

0.74

1.0

1.2

nmol/l

34.0

29.5

—

(3017895) Helicobacter pylori Ab [Units/volume] in Serum

168

1.39

0.73

1.4

1.6

—

(3045683) HLA typing for celiac disease panel - Blood or Tissue

1.81

0.72

1.0

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

265

1.30

0.72

2.3

1.4

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

1.63

0.72

5.0

3.3

u/ml

40.9

41.5

0.01

(3018418) pH of Serum or Plasma

134

1204

1.16

0.72

5.9

3.5

7.4

0.54

228

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

416

4046

1.21

0.71

4.6

4.2

mmol/l

5.7

0.22

385

3722

(40761511) CBC panel - Blood by Automated count

446

4369

1.28

0.70

14.4

11.5

—

(3026285) Alpha 1 antitrypsin [Mass/volume] in Serum or Plasma

1.72

0.70

1.1

1.0

g/l

1.8

1.5

—

(3032080) INR in Blood by Coagulation assay

156

1420

1.15

0.70

8.2

7.1

inr

1.2

1.1

0.49

439

(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay

1.61

0.69

2.0

1.2

—

(21494434) Karyotype in Bone marrow

1.86

0.68

1.0

1.1

—

(3042975) Streptococcus sp identified in Isolate by Organism specific culture

1.86

0.68

1.2

1.1

—

(3007461) Platelets [#/volume] in Blood

468

4617

1.47

0.68

24.7

18.3

e9/l

264.1

264.5

0.05

460

4509

(3024891) Influenza virus A+B Ag [Presence] in Specimen

119

1.44

0.68

1.2

—

(3032035) Polymorphonuclear cells/100 leukocytes in Blood

0.53

0.67

3.8

3.5

65.6

58.0

—

(3024731) MCV [Entitic volume]

468

4618

1.46

0.67

24.7

18.3

91.2

90.9

0.98

463

4555

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

202

0.68

0.67

2.5

2.4

—

(40768797) Stomach Pathology biopsy report

609

1.19

0.67

1.1

1.2

—

(3036603) Volume of Urine

1.79

0.66

1.6

1.5

—

2474.6

—

(3026361) Erythrocytes [#/volume] in Blood

468

4619

1.45

0.65

24.8

18.3

e12/l

4.4

1.16

459

4497

(3035941) MCH [Entitic mass]

468

4619

1.45

0.65

24.6

18.2

30.3

30.1

1.38

463

4555

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

866

1.17

0.65

1.4

1.3

u/ml

6.7

12.4

0.56

341

(3002179) Metamyelocytes/100 leukocytes in Blood

306

1.26

0.64

4.9

4.0

0.7

0.5

0.30

(3010813) Leukocytes [#/volume] in Blood

468

4620

1.45

0.64

24.8

18.4

e9/l

6.6

6.5

0.28

460

4493

(4024509)

1.73

0.64

1.2

1.4

—

(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma

138

1254

1.14

0.63

3.9

2.3

u/l

54.3

55.0

0.11

132

1160

(1001926) Buprenorphine [Presence] in Urine by Screen method

121

1.42

0.63

3.2

1.4

—

(3000963) Hemoglobin [Mass/volume] in Blood

468

4621

1.44

0.63

24.8

18.4

g/l

131.6

132.5

0.79

462

4557

(3027008) Opiates [Presence] in Urine

147

1.38

0.62

3.3

1.3

—

(3035999) Lactate [Moles/volume] in Cerebral spinal fluid

1.67

0.61

1.4

mmol/l

2.8

1.9

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

502

1.20

0.61

1.8

1.9

—

(3036481) Cortisol [Moles/volume] in Serum or Plasma

391

1.22

0.61

2.4

2.1

nmol/l

351.6

369.4

0.24

368

(3000764) Benzodiazepines [Presence] in Urine

148

1.37

0.60

3.3

1.4

—

(3046896) Herpes virus 6 DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

0.60

0.0

1.0

—

(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma

467

1.20

0.59

1.7

1.6

1.4

1.3

0.47

415

(3028300) Cannabinoids [Presence] in Urine

149

1.36

0.58

3.3

1.4

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

430

4209

1.20

0.58

5.0

4.6

mmol/l

2.9

0.34

401

3896

(40764127) Haemophilus influenzae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.58

0.0

1.5

—

(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.58

0.0

1.5

—

(3044889) 12 lead EKG panel

295

2819

1.12

0.57

3.8

3.4

—

(40768441) Liver Pathology biopsy report

1.67

0.57

3.0

1.5

—

(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection

1.46

0.56

1.7

1.3

—

(3003694) ABO and Rh group [Type] in Blood

122

1110

1.13

0.55

1.4

1.5

—

(3050238) Crystals [Presence] in Synovial fluid by Light microscopy

1.43

0.54

1.4

—

(3021589) Normoblasts [#/volume] in Blood

194

1818

1.11

0.53

11.5

8.7

e9/l

0.0

0.48

162

1500

(3044355) Beta 2 glycoprotein 1 IgG Ab [Units/volume] in Serum or Plasma by Immunoassay

1.53

0.53

1.2

u/ml

1.4

2.0

—

(3001122) Ferritin [Mass/volume] in Serum or Plasma

214

2017

1.11

0.52

3.4

2.8

ug/l

97.6

80.5

0.84

203

1869

(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection

1.41

0.51

2.2

1.6

—

(3016650) Hepatitis A virus Ab [Presence] in Serum

1.39

0.51

1.1

—

(43055554) Base excess.100% oxygenated [Moles/volume] standard in Capillary blood by calculation

180

1.29

0.50

3.5

3.3

mmol/l

1.9

1.7

0.12

140

(3016018) Differential panel - Cerebral spinal fluid

1.47

0.50

1.7

2.0

—

(4268621)

1.47

0.50

2.0

2.2

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

404

3946

1.15

0.50

13.5

11.1

ml/min/173m2

83.1

83.8

0.26

336

3197

(3049717) Cytology report of Urine Cyto stain

101

1.40

0.50

2.0

2.3

—

(3020961) Endomysium IgA Ab [Titer] in Serum

235

1.25

0.49

1.1

—

195.0

—

(3047181) Lactate [Moles/volume] in Blood

110

1.38

0.49

1.9

5.8

mmol/l

1.0

1.2

0.78

101

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

110

1.38

0.49

1.5

1.3

—

(3018171) Choriogonadotropin [Units/volume] in Serum or Plasma

199

1.27

0.49

1.7

1.9

u/l

1970.4

3470.2

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

868

1.13

0.48

1.3

iu/ml

23.1

32.3

0.63

291

(3020630) Protein [Mass/volume] in Serum or Plasma

273

1.22

0.47

3.2

2.8

g/l

68.8

67.8

0.31

253

(40760892) CBC W Ordered Manual Differential panel - Blood

110

1005

1.12

0.47

6.2

4.4

—

(3000570) Elastase.pancreatic [Mass/mass] in Stool

120

1.34

0.46

1.6

1.3

ug/g

268.0

303.7

—

(3010421) pH of Blood

0.59

0.46

1.8

3.3

7.5

7.4

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

100

910

1.12

0.46

1.6

1.5

—

(3037121) Protein [Mass/volume] in Urine

121

1.33

0.44

3.3

2.9

g/l

0.1

0.2

—

(40760888) Immunoglobulin light chains.free panel - Serum

1.46

0.44

5.0

4.8

—

(3021788) Differential panel - Synovial fluid

1.46

0.44

2.0

1.7

—

(3016879) Cocaine [Presence] in Urine

139

1.31

0.44

3.6

1.4

—

(3022756) Ceruloplasmin [Mass/volume] in Serum or Plasma

1.62

0.43

1.0

1.1

mg/l

274.2

298.5

—

(3017446) Testosterone [Moles/volume] in Serum or Plasma

1.62

0.43

3.0

1.3

nmol/l

1.3

1.5

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

122

1.32

0.43

1.8

1.2

—

(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability

1.44

0.42

1.3

1.2

—

(3027544) Mycobacterium sp identified in Sputum by Organism specific culture

1.52

0.41

3.2

3.9

—

(3036432) Mycobacterium tuberculosis genotype [Identifier] in Isolate

0.00

0.41

0.0

6.5

—

(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.41

0.0

1.1

—

(3004451) EKG impression Narrative

0.00

0.41

0.0

1.3

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

362

3527

1.11

0.41

4.8

4.5

pmol/l

14.5

14.6

0.03

337

3251

(3004588) Protein electrophoresis panel - Serum or Plasma

241

1.22

0.41

2.9

2.3

—

(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma

1.40

0.41

2.6

2.0

—

(3004409) Coagulation factor X activity actual/normal in Platelet poor plasma by Coagulation assay

0.00

0.40

0.0

1.0

—

110.6

—

(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay

0.00

0.40

0.0

1.0

—

131.7

—

(3005353) Prothrombin activity actual/normal in Platelet poor plasma by Coagulation assay

0.00

0.40

0.0

1.0

—

101.7

—

(3025941) Bacteria identified in Stool by Culture

260

1.21

0.40

1.3

1.2

—

(3019601) Blood group antibody investigation [Interpretation] in Plasma or RBC

1.48

0.40

1.4

1.8

—

(42869547) Procollagen type III.N-terminal propeptide [Mass/volume] in Serum

0.00

0.39

0.0

1.2

—

8.7

—

(3004775) Volume in Urine collected for unspecified duration

0.00

0.39

0.0

2.8

—

676.5

—

(3029075) Extractable nuclear Ab panel - Serum

0.00

0.39

0.0

1.0

—

(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma

0.00

0.39

0.0

1.2

—

109.7

—

(3016750) Collection duration of Urine

0.00

0.39

0.0

2.4

—

497.1

—

(3016417) Amylase.pancreatic [Enzymatic activity/volume] in Serum or Plasma

355

1.17

0.38

3.8

2.1

u/l

35.4

31.3

0.47

294

(40761536) Microorganisms panel - Urine sediment

353

0.84

0.37

4.0

3.5

—

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

299

0.83

0.37

1.6

1.4

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

329

1.17

0.36

1.3

1.2

—

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

386

3781

1.10

0.36

5.5

5.1

mmol/mol

38.8

38.7

0.04

359

3516

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

1.34

0.36

2.0

1.6

—

(4062490)

1.43

0.35

1.3

1.4

—

(3023511) Choriogonadotropin [Units/volume] in Urine

124

0.72

0.35

1.8

1.3

—

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

421

4144

1.13

0.35

4.6

4.1

mmol/l

4.8

4.9

0.52

396

3862

(40768793) Breast Pathology biopsy report

178

0.78

0.35

1.1

1.3

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

378

1.15

0.34

3.2

—

(3034860) Kappa light chains.free [Mass/volume] in Serum

1.33

0.34

4.8

4.2

mg/l

37.9

40.3

0.07

(3047169) Lambda light chains.free [Mass/volume] in Serum or Plasma

1.33

0.34

4.8

4.2

mg/l

22.2

22.7

0.04

(3010156) C reactive protein [Mass/volume] in Serum or Plasma by High sensitivity method

191

1.21

0.34

1.7

1.9

mg/l

2.5

2.3

0.05

134

(3035637) Corticotropin [Mass/volume] in Plasma

1.31

0.33

1.7

1.8

—

(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection

1.31

0.33

1.5

1.6

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

409

4024

1.11

0.32

5.6

5.3

mu/l

1.8

2.1

0.62

382

3735

(3026782) Osmolality of Urine

727

1.10

0.31

3.7

2.5

mosm/kgh2o

472.9

521.8

1.13

629

(3021387) Prolactin [Units/volume] in Serum or Plasma

164

0.79

0.31

1.3

1.7

mu/l

261.7

315.5

0.69

144

(4010399)

278

1.16

0.30

1.6

1.4

—

(3027944) Amphetamines [Presence] in Urine

148

1.22

0.29

3.2

1.4

—

(3025839) Triglyceride [Moles/volume] in Serum or Plasma

120

1130

1.08

0.29

1.8

1.6

mmol/l

1.3

1.4

0.21

101

965

(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection

1.25

0.29

1.6

—

(21494755) Public health laboratory ask at order entry panel

452

1.12

0.28

1.3

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

297

2894

1.07

0.27

3.1

3.3

—

(3019060) Gas panel - Arterial blood

196

1.18

0.27

2.6

4.6

—

(1002224) Polysomnography panel

196

1.18

0.27

1.1

—

(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing

1.22

0.27

1.6

—

(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum

1.22

0.27

1.5

1.2

—

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

289

2816

1.07

0.26

3.6

2.8

u/l

57.5

42.9

0.72

273

2645

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

224

0.84

0.26

1.2

1.5

—

(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma

142

1355

1.07

0.25

4.9

3.0

u/l

32.3

28.3

0.77

137

1296

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.73

0.24

1.3

1.8

—

(3009542) Hematocrit [Volume Fraction] of Blood

391

3854

1.08

0.23

16.1

13.0

39.5

39.3

0.13

287

2914

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

162

1.18

0.23

6.9

8.7

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.77

0.22

2.4

1.5

—

(3014051) Protein [Presence] in Urine by Test strip

0.73

0.22

2.7

2.1

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

663

1.08

0.22

3.8

3.6

ng/l

191.3

269.1

0.19

463

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

135

1.19

0.21

4.4

2.0

—

(3027135) IgG subclass 1 [Mass/volume] in Serum

1.19

0.21

1.4

g/l

9.8

7.2

—

(3024139) IgG subclass 3 [Mass/volume] in Serum

1.19

0.21

1.4

g/l

0.6

0.3

—

(3028192) IgG subclass 2 [Mass/volume] in Serum

1.19

0.21

1.4

g/l

2.5

2.6

—

(3007798) IgG/Albumin [Mass Ratio] in Cerebral spinal fluid

0.00

0.21

0.0

1.0

—

(40761539) Cells [Type] in Urine sediment by Light microscopy

0.00

0.21

0.0

1.0

—

(3013247) Albumin in CSF/Albumin in Serum or Plasma

0.00

0.21

0.0

1.0

—

6.3

—

(3014300) Beta 2 glycoprotein 1 IgM Ab [Units/volume] in Serum

0.00

0.21

0.0

1.2

—

(3027231) Wheat IgE Ab [Units/volume] in Serum

0.00

0.21

0.0

1.0

—

(3001019) Free T4 and TSH panel - Serum or Plasma

345

1.11

0.21

2.1

1.8

—

(3035544) Cardiolipin IgG Ab [Units/volume] in Serum or Plasma

0.00

0.21

0.0

1.2

—

(3029396) Erythrocyte agglutination [Presence] in Blood

0.00

0.21

0.0

2.8

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

221

1.14

0.20

2.1

1.5

—

(3005570) Glucose [Moles/volume] in Urine

1.23

0.20

1.7

2.4

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

416

0.91

0.20

2.1

1.6

—

(3011288) Drugs identified in Urine by Screen method

1.22

0.20

5.3

1.6

—

(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid

1.18

0.19

1.2

1.1

—

(4281824)

1.19

0.18

1.1

—

(3044941) Cell count panel - Synovial fluid

1.17

0.18

1.4

1.6

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

142

0.84

0.17

1.3

1.5

—

(3023150) Myeloperoxidase Ab [Units/volume] in Serum

1.13

0.17

1.0

1.3

—

(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence

1.11

0.17

1.6

1.2

—

(36305247) Microscopic observation [Identifier] in Isolate by Gram stain

101

1.19

0.16

1.6

1.4

—

(3008898) HLA-B27 [Presence]

203

0.88

0.15

1.0

1.1

—

(3002523) Influenza virus A Ag [Presence] in Specimen

1.14

0.15

1.1

—

(3003740) Influenza virus B Ag [Presence] in Specimen

1.14

0.15

1.1

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.81

0.14

1.1

1.5

—

(4094501)

0.80

0.13

1.1

—

(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay

151

1.13

0.13

2.7

1.9

—

(3019473) Protein [Mass/volume] in Cerebral spinal fluid

117

0.85

0.13

1.4

1.3

mg/l

1387.4

429.4

—

107

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

400

3967

1.05

0.12

4.1

3.7

mmol/l

1.3

1.2

1.17

367

3657

(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection

1.18

0.12

2.2

1.6

—

(3000492) Spirometry study

395

1.07

0.12

1.4

—

(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight

137

0.87

0.12

1.3

1.4

—

(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma

137

0.87

0.12

1.3

1.4

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

137

0.87

0.12

1.3

1.4

—

(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma

137

0.87

0.12

1.3

1.4

—

(3029634) Reagin Ab [Titer] in Serum by VDRL

1.14

0.10

1.2

—

(3029080) Hemoglobin [Entitic mass] in Reticulocytes

1.11

0.10

1.8

1.4

30.6

31.7

—

(3005033) Fetal Nuchal fold Thickness US

114

0.87

0.09

1.3

1.4

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

114

0.87

0.09

1.3

1.4

—

(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection

1.06

0.09

1.8

1.7

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

482

0.95

0.09

1.5

1.4

—

(3032773) Endomysium IgG Ab [Titer] in Serum

1.04

0.09

1.0

1.1

—

(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection

1.11

0.09

1.7

1.6

—

(3005136) Cladosporium herbarum IgE Ab [Units/volume] in Serum

1.09

0.09

1.0

—

0.0

—

(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture

1.09

0.09

1.0

1.2

—

(3009466) Valproate [Moles/volume] in Serum or Plasma

0.82

0.08

3.8

6.3

umol/l

274.2

396.2

—

(3005702) Mycobacterium sp identified in Specimen by Organism specific culture

1.08

0.08

1.3

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.84

0.07

1.2

1.1

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

415

4129

1.04

0.07

4.5

4.1

mmol/l

1.6

1.02

386

3830

(3041096) Erythrocytes [Presence] in Urine by Automated

119

1168

1.03

0.06

3.6

3.2

—

(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood

148

1.08

0.06

4.4

3.3

43.6

45.0

0.08

148

(3022621) pH of Urine by Test strip

263

0.95

0.05

2.7

2.6

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

119

0.92

0.04

1.3

1.5

—

(3003785) Carcinoembryonic Ag [Mass/volume] in Serum or Plasma

393

1.02

0.01

3.9

3.8

ug/l

2.9

9.8

2.72

317

(3044290) Cell count panel - Cerebral spinal fluid

1.07

0.01

1.5

1.6

—

(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma

146

1.03

0.00

1.3

1.5

—

(3018677) aPTT in Platelet poor plasma by Coagulation assay

525

1.01

0.00

2.6

1.7

29.3

0.04

510

(3050129) First trimester maternal screen panel - Serum or Plasma

152

0.99

0.00

1.2

1.5

—

(3003327) Ova and parasites identified in Stool by Light microscopy

158

1.01

0.00

1.9

1.8

—

(3019832) Treponema pallidum Ab [Presence] in Serum

427

1.01

0.00

1.3

1.6

—

(4133840)

0.00

0.0

1.0

—

(3009306) Alpha-1-Fetoprotein [Mass/volume] in Serum or Plasma

0.00

0.0

2.0

—

(3013466) aPTT in Blood by Coagulation assay

0.00

0.0

1.0

—

33.9

—

(3015479) Mycobacterium sp identified in Blood by Organism specific culture

0.00

0.0

1.4

—

(3019083) Insulin-like growth factor [Moles/volume] in Serum or Plasma

0.00

0.0

1.7

—

(3046426) Aquaporin 4 water channel IgG Ab [Presence] in Serum or Plasma

0.00

0.0

1.0

—

(3001850) Coagulation factor XI activity actual/normal in Platelet poor plasma by Coagulation assay

0.00

0.0

1.0

—

(3029715) Chromosome analysis.interphase [Interpretation] in Bone marrow by FISH Narrative

0.00

0.0

1.0

—

(3010937) Rubella virus Ab [Presence] in Serum

0.00

0.0

1.0

—

(37020271) Myelin oligodendrocyte glycoprotein Ab [Titer] in Serum by Cell binding immunofluorescent assay

0.00

0.0

1.2

—

(3039602) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Capillary blood

0.00

0.0

2.6

—

1.2

—

(3006576) Bicarbonate [Moles/volume] in Blood

0.00

0.0

5.0

—

26.3

—

(3000213) Normetanephrine [Moles/time] in 24 hour Urine

0.00

0.0

1.3

—

1.6

—

(3017115) Methotrexate [Moles/volume] in Serum or Plasma

0.00

0.0

5.2

—

0.2

—

(3032700) Glomerular basement membrane Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3006695) Toxoplasma gondii DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.2

—

(3044007) Cell count panel - Peritoneal fluid

0.00

0.0

1.1

—

(3002348) Coagulation factor XII activity actual/normal in Platelet poor plasma by Coagulation assay

0.00

0.0

1.0

—

(3000285) Sodium [Moles/volume] in Blood

0.00

0.0

1.0

—

(3044009) aPTT.lupus sensitive (LA screen)

0.00

0.0

1.3

—

(3012741) Chlamydophila pneumoniae IgA Ab [Titer] in Serum

0.00

0.0

1.0

—

(3027238) Thyroperoxidase Ab [Units/volume] in Serum or Plasma

390

1.00

0.00

1.2

iu/ml

98.0

167.0

0.93

179

(3004269) Kappa light chains [Mass/time] in 24 hour Urine

0.00

0.0

4.8

—

(3002619) Bacteria identified in Specimen by Culture

0.00

0.0

1.1

—

(3028009) Chlamydia trachomatis IgG Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(1002183) Plasma cells monotypic population [Identifier] in Bone marrow by Flow cytometry (FC)

0.00

0.0

1.2

—

(3031072) Herpes simplex virus 1 IgG Ab [Presence] in Cerebral spinal fluid

0.00

0.0

1.2

—

(44816559) Phosphatidylethanol [Mass/volume] in Blood

0.99

0.00

1.0

1.1

—

(3038177) Helicobacter pylori Ab [Presence] in Serum

0.87

0.00

1.0

1.2

—

(3002067) Lambda light chains [Mass/time] in 24 hour Urine

0.00

0.0

4.8

—

(3007695) Herpes simplex virus 2 IgG Ab [Presence] in Cerebral spinal fluid

0.00

0.0

1.2

—

(3019174) dRVVT (LA screen)

0.00

0.0

1.1

—

(3051659) 25-hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

0.00

0.0

1.4

—

(3023383) Lactate [Moles/volume] in Pleural fluid

0.00

0.0

1.0

—

5.0

—

(3051339) Copper [Moles/volume] in Blood

0.00

0.0

1.2

—

17.7

—

(40760435) Tropomyosin IgE Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3012984) Norclozapine [Mass/volume] in Serum or Plasma

0.00

0.0

8.4

—

(3041806) Other cells [#/volume] in Blood by Manual count

0.00

0.0

2.0

—

(44806420)

0.00

0.0

2.3

—

(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.95

0.00

1.7

1.6

—

(3035457) Cefaclor IgE Ab [Units/volume] in Serum

0.00

0.0

1.1

—

(3037756) Immunofixation for Serum or Plasma

0.99

0.00

4.0

2.0

—

(42868499) Enterovirus IgG Ab [Presence] in Cerebral spinal fluid by Immunoassay

0.00

0.0

1.1

—

(21491866) Provasopressin.C-terminal [Moles/volume] in Serum or Plasma by Immunoassay

0.00

0.0

1.0

—

4.9

—

(3025549) Creatine [Moles/time] in 24 hour Urine

0.00

0.0

1.7

—

(3016330) Potassium [Moles/time] in 24 hour Urine

0.00

0.0

1.2

—

(3028717) Thiamine [Mass/volume] in Blood

0.00

0.0

1.4

—

(3006109) Coagulation factor IX activity actual/normal in Platelet poor plasma by Coagulation assay

0.00

0.0

1.0

—

117.5

—

Mortality – FinRegistry

↥

Association

Association between endpoint N14_VAGINAL_HSIL and mortality.

Females

Parameter	HR [95% CI]	p-value
N14_VAGINAL_HSIL	1.265 [1.08, 1.48]	0.003
Birth year	0.998 [0.99, 1.01]	0.566

During the follow-up period (1.1.1998 — 31.12.2019), 266 out of 2226 females with N14_VAGINAL_HSIL died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have N14_VAGINAL_HSIL.

N-year risk	Females	Males
1	0.089%	No data
5	0.774%	No data
10	1.998%	No data
15	3.721%	No data
20	6.738%	No data

Relationships between endpoints

↥

Index endpoint: N14_VAGINAL_HSIL – HSIL lesion of the vagina

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

Extremity

rg [CI]

Extremity

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

HSIL lesion of the vagina

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints