No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
80 |
4. Check minimum number of eventsNone |
80 |
5. Include endpointsNone |
80 |
6. Filter based on genotype QC (FinnGen only) |
80 |
Control definitions (FinnGen only)
- Control exclude
- N14_GLOMERULAR
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- N00-N08
- Name in latin
- Syndroma nephriticum cito progrediens
Similar endpoints
↥List of similar endpoints to
Rapidly progressive nephritic syndrome
based on the number of shared cases.
Similar with more cases:
- Glomerulonephritis
- Glomerular diseases
- Genitourinary diseases
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 618 | 323 | 291 |
| Only index persons | 464 | 246 | 218 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 58.72 | 58.87 | 58.31 |
| Only index persons | 52.82 | 52.51 | 53.16 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 80 | 40 | 40 |
| Unadjusted period prevalence (%) | 0.02 | 0.01 | 0.02 |
| Median age at first event (years) | 55.12 | 48.02 | 62.22 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
No data available
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3012516) Albumin [Mass/volume] in Urine
48
159
6.05
14.66
9.9
3.5
mg/l
300.7
55.1
2.66
42
107
(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma
14
11
15.21
14.64
1.5
1.5
—
—
—
0
0
(3020682) Albumin/Creatinine [Ratio] in Urine
49
170
5.86
14.05
12.4
4.2
mg/mmol
58.8
7.1
3.22
44
116
(3017766) Complement C4 [Mass/volume] in Serum or Plasma
13
11
13.92
12.96
2.0
1.4
g/l
0.3
0.2
0.74
13
11
(3000504) BK virus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection
11
0
+∞
11.74
2.8
0.0
—
—
—
0
0
(3017143) Hepatitis C virus Ab [Presence] in Serum
29
81
5.05
10.27
2.4
1.7
—
—
—
0
0
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
59
286
5.05
10.15
38.4
8.2
mmol/l
1.2
1.2
0.15
47
239
(40762485) Glomerular basement membrane Ab [Units/volume] in Serum by Immunoassay
13
6
25.43
9.71
1.3
1.2
—
—
—
0
0
(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay
13
17
8.94
9.57
2.1
1.8
—
—
—
0
0
(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma
14
9
18.49
9.44
7.6
3.6
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
50
223
4.31
9.40
17.0
2.9
—
—
—
0
0
(3012544) pH of Venous blood
22
52
5.46
9.36
15.5
4.2
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
31
104
4.23
8.52
2.3
1.8
—
—
—
0
0
(3018418) pH of Serum or Plasma
42
176
3.92
8.41
18.9
4.8
ph
7.4
7.4
2.05
12
38
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
12
17
8.13
8.24
4.3
2.4
—
—
—
0
0
(3023520) Reticulocytes [#/volume] in Blood
21
57
4.64
7.50
3.7
4.6
e9/l
68.3
73.3
0.28
15
44
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
12
19
7.25
7.48
1.9
1.9
—
—
—
0
0
(3023368) Bacteria identified in Blood by Culture
41
180
3.62
7.47
10.0
4.3
—
—
—
0
0
(3000991) Gas panel - Venous blood
19
48
4.88
7.39
35.5
8.4
—
—
—
0
0
(3037756) Immunofixation for Serum or Plasma
11
16
7.81
7.35
1.6
1.7
—
—
—
0
0
(42870588) Differential panel, method unspecified - Blood
45
212
3.57
7.30
12.4
6.1
—
—
—
0
0
(3015736) pH of Urine
48
237
3.56
7.20
7.9
3.9
—
—
—
0
0
(3021440) Promyelocytes/100 leukocytes in Blood
19
49
4.77
7.20
7.2
5.5
%
0.1
0.3
—
8
19
(36304419) Bacteria [Presence] in Urine
40
177
3.52
7.13
12.1
2.5
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
32
127
3.53
6.69
2.4
2.2
—
—
—
0
0
(3006504) Eosinophils/100 leukocytes in Blood
53
289
3.47
6.58
14.1
6.7
%
2.1
2.6
1.20
53
271
(3019069) Monocytes/100 leukocytes in Blood
53
290
3.45
6.53
14.2
7.1
%
9.4
8.6
1.07
53
274
(3002179) Metamyelocytes/100 leukocytes in Blood
18
48
4.55
6.51
5.0
5.6
%
0.2
0.4
—
6
15
(3007778) Kappa light chains/Lambda light chains [Mass Ratio] in Serum
12
22
6.24
6.51
1.8
4.8
—
—
—
0
0
(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
10
15
7.48
6.47
2.1
1.9
—
—
—
0
0
(3028026) IgM [Mass/volume] in Serum or Plasma
16
39
4.88
6.44
1.6
1.5
g/l
1.0
1.1
0.27
16
31
(3022096) Basophils/100 leukocytes in Blood
52
283
3.39
6.43
14.4
6.5
%
0.5
0.6
0.95
52
264
(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain
9
5
19.99
6.42
1.3
1.0
—
—
—
0
0
(3002030) Lymphocytes/100 leukocytes in Blood
53
293
3.40
6.36
14.2
6.9
%
25.2
27.3
0.67
53
273
(3017181) Myelocytes/100 leukocytes in Blood
19
54
4.30
6.34
7.3
5.3
%
0.6
0.8
—
9
21
(3052318) Alpha-1-Microglobulin [Mass/volume] in Urine
6
0
+∞
6.32
2.2
0.0
—
—
—
0
0
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
11
19
6.55
6.29
2.0
1.9
—
—
—
0
0
(3018010) Neutrophils/100 leukocytes in Blood
52
289
3.28
6.09
13.2
6.6
%
59.2
57.3
0.49
52
272
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
10
9
12.48
5.98
2.1
1.6
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
40
195
3.10
5.81
5.4
3.6
—
—
—
0
0
(3032080) INR in Blood by Coagulation assay
46
243
3.10
5.80
21.6
8.7
inr
1.1
1.2
0.61
17
73
(3021879) Hepatitis B virus core Ab [Presence] in Serum
17
48
4.23
5.69
1.5
1.6
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
23
81
3.58
5.67
2.0
1.8
—
—
—
0
0
(3027945) Reticulocytes/100 erythrocytes in Blood
23
82
3.53
5.56
3.7
3.9
%
2.0
1.8
0.44
23
73
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
17
49
4.14
5.53
3.0
1.6
—
—
—
0
0
(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection
9
8
12.47
5.44
2.2
1.1
—
—
—
0
0
(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)
15
40
4.38
5.38
4.3
2.9
ml/min/173m2
41.6
65.7
—
8
15
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
19
61
3.77
5.33
6.3
4.0
—
—
—
0
0
(3004588) Protein electrophoresis panel - Serum or Plasma
15
41
4.27
5.21
1.6
3.2
—
—
—
0
0
(3042631) Mycobacterium sp identified in Specimen
9
9
11.07
5.17
4.6
4.3
—
—
—
0
0
(3048929) Epstein Barr virus Ab [Presence] in Serum
10
20
5.57
4.92
1.2
1.6
—
—
—
0
0
(3025159) Blasts/100 leukocytes in Blood
16
48
3.92
4.91
6.7
5.6
%
0.0
0.5
—
7
17
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
14
38
4.25
4.89
41.4
6.6
mmol/l
24.1
25.0
0.34
14
38
(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection
7
5
15.14
4.66
2.3
1.6
—
—
—
0
0
(3021601) Nitrite [Presence] in Urine by Test strip
51
310
2.78
4.60
15.3
5.6
estimate
0.0
0.0
0.00
14
66
(3035350) Ketones [Presence] in Urine by Test strip
51
311
2.77
4.56
11.3
4.1
estimate
0.0
0.0
0.00
13
67
(3037467) Urinalysis macro (dipstick) panel - Urine
62
423
3.07
4.39
16.3
4.5
—
—
—
0
0
(3029634) Reagin Ab [Titer] in Serum by VDRL
8
9
9.71
4.39
2.0
1.2
—
—
—
0
0
(3009261) Glucose [Presence] in Urine by Test strip
51
317
2.68
4.29
11.3
4.2
estimate
0.0
0.0
0.00
12
64
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
20
76
3.18
4.29
2.1
1.7
—
—
—
0
0
(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection
9
13
7.64
4.29
2.2
1.2
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
20
77
3.13
4.20
2.0
1.8
—
—
—
0
0
(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay
9
14
7.09
4.11
1.2
1.4
—
—
—
0
0
(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection
9
14
7.09
4.11
1.8
1.6
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
26
118
2.78
4.08
2.3
1.9
—
—
—
0
0
(40760888) Immunoglobulin light chains.free panel - Serum
9
15
6.61
3.94
1.2
6.1
—
—
—
0
0
(3023150) Myeloperoxidase Ab [Units/volume] in Serum
9
15
6.61
3.94
5.0
1.1
—
—
—
0
0
(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection
7
8
9.44
3.85
2.6
1.1
—
—
—
0
0
(3023419) Bacteria identified in Sputum by Culture
7
8
9.44
3.85
3.6
2.4
—
—
—
0
0
(3004616) Nuclear Ab [Presence] in Serum
6
5
12.81
3.82
1.7
1.0
—
—
—
0
0
(3017704) Immunofixation for Urine
6
5
12.81
3.82
1.2
1.0
—
—
—
0
0
(3022313) Gas panel - Capillary blood
12
35
3.86
3.79
20.8
3.6
—
—
—
0
0
(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay
8
12
7.26
3.77
1.6
1.2
—
—
—
0
0
(3000093) Morphology [Interpretation] in Blood Narrative
6
6
10.67
3.55
1.2
1.5
—
—
—
0
0
(3015235) Bicarbonate [Moles/volume] in Capillary blood
9
18
5.49
3.48
7.2
2.1
mmol/l
22.6
23.6
—
9
13
(1616796) Gas panel - Central venous blood
8
14
6.21
3.43
11.9
3.1
—
—
—
0
0
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
20
86
2.77
3.42
1.3
1.2
u/ml
53.3
9.9
—
5
37
(3000494) Fungus identified in Specimen by Culture
17
67
2.95
3.39
1.8
1.3
—
—
—
0
0
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
10
28
3.94
3.31
42.3
10.5
—
—
—
0
0
(3049717) Cytology report of Urine Cyto stain
9
20
4.93
3.22
2.4
2.4
—
—
—
0
0
(3004119) Hemoglobin [Mass/volume] in Venous blood
11
34
3.59
3.19
9.9
4.8
g/l
112.2
124.3
1.21
11
34
(3044927) Protein electrophoresis panel - Urine
6
8
7.99
3.11
1.2
1.1
—
—
—
0
0
(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma
49
329
2.26
3.09
9.1
6.3
umol/l
9.2
11.8
2.03
49
313
(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection
7
12
6.27
3.09
2.0
1.6
—
—
—
0
0
(21493690) Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood
5
5
10.54
3.02
1.8
1.6
—
—
—
0
0
(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection
5
5
10.54
3.02
2.4
1.4
—
—
—
0
0
(3027273) Bicarbonate [Moles/volume] in Venous blood
10
30
3.67
3.02
7.5
5.2
mmol/l
24.5
24.4
—
10
30
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
8
17
5.10
3.00
1.6
1.4
—
—
—
0
0
(3027529) Toxoplasma gondii IgM Ab [Units/volume] in Serum
6
9
7.10
2.92
1.0
1.4
—
—
—
0
0
(3045424) Erythrocytes [Presence] in Urine
6
9
7.10
2.92
1.3
1.0
—
—
—
0
0
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
6
9
7.10
2.92
2.2
1.1
—
—
—
0
0
(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum
6
9
7.10
2.92
2.0
2.9
—
—
—
0
0
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
9
23
4.27
2.87
2.1
3.2
—
—
—
0
0
(3021901) Oxygen saturation in Capillary blood
7
14
5.36
2.79
5.4
2.3
—
—
—
0
0
(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection
7
14
5.36
2.79
2.0
1.6
—
—
—
0
0
(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection
7
14
5.36
2.79
2.0
1.5
—
—
—
0
0
(3017817) Protein [Mass] in Urine collected for unspecified duration
5
6
8.78
2.79
3.2
6.7
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
17
75
2.61
2.74
1.6
1.6
—
—
—
0
0
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
11
38
3.20
2.70
2.1
1.3
—
—
—
0
0
(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma
19
90
2.46
2.65
1.4
1.1
iu/ml
40.4
37.5
0.05
11
30
(3029937) Albumin [Presence] in Urine by Test strip
31
182
2.15
2.64
11.6
4.2
estimate
0.0
0.0
—
9
62
(3032035) Polymorphonuclear cells/100 leukocytes in Blood
6
11
5.79
2.59
4.0
4.5
%
59.8
59.0
—
6
11
(3030905) Polymorphonuclear cells [#/volume] in Blood
6
11
5.79
2.59
3.8
4.5
e9/l
4.3
4.1
—
6
11
(3045414) Leukocytes [Presence] in Urine
8
21
4.11
2.54
2.5
1.8
—
—
—
0
0
(3027315) Oxygen [Partial pressure] in Blood
7
16
4.68
2.53
12.9
2.6
kpa
8.6
8.3
—
7
16
(3013290) Carbon dioxide [Partial pressure] in Blood
7
16
4.68
2.53
12.9
2.6
kpa
5.0
5.0
—
7
16
(3005322) IgE [Units/volume] in Serum or Plasma
10
35
3.12
2.40
1.4
1.3
u/ml
94.7
141.3
—
10
27
(40760892) CBC W Ordered Manual Differential panel - Blood
25
140
2.14
2.36
9.5
5.9
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
24
133
2.15
2.33
9.2
4.2
—
—
—
0
0
(40758558) Short blood count panel - Blood
26
151
2.07
2.23
10.1
8.5
—
—
—
0
0
(3015171) Extractable nuclear Ab [Units/volume] in Serum
7
19
3.93
2.20
1.3
1.3
—
—
—
0
0
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
10
37
2.95
2.19
2.2
1.6
—
—
—
0
0
(3052851) Hemolysis interference index of Serum or Plasma
6
14
4.54
2.19
1.8
4.2
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
41
284
1.91
2.11
5.6
4.6
—
—
—
0
0
(3016407) Fibrinogen [Mass/volume] in Platelet poor plasma by Coagulation assay
6
16
3.96
1.97
10.7
3.2
g/l
3.1
3.3
—
6
16
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
37
253
1.86
1.94
12.5
4.3
—
—
—
0
0
(3005895) Myoglobin [Mass/volume] in Serum or Plasma
7
22
3.38
1.93
3.1
2.3
ug/l
10524.6
378.4
—
7
22
(3016417) Amylase.pancreatic [Enzymatic activity/volume] in Serum or Plasma
13
60
2.39
1.90
1.6
2.1
u/l
32.0
26.4
0.46
13
50
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
8
29
2.95
1.85
9.6
3.1
%
0.9
1.3
—
8
29
(4035726)
12
54
2.44
1.84
1.8
1.4
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
31
206
1.82
1.75
4.0
2.6
—
—
—
0
0
(40761535) Cells panel - Urine sediment
11
50
2.39
1.65
14.4
4.5
—
—
—
0
0
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
6
20
3.16
1.61
3.2
1.2
—
—
—
0
0
(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis
5
15
3.48
1.54
2.2
4.2
g/l
0.0
0.0
—
5
15
(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma
13
66
2.16
1.54
2.4
2.1
umol/l
5.1
5.8
0.17
13
56
(3024889) Methemoglobin/Hemoglobin.total in Venous blood
7
28
2.64
1.49
10.7
3.0
%
0.7
0.7
—
7
28
(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood
7
28
2.64
1.49
9.1
4.4
%
44.9
50.7
—
7
28
(3034780) Angiotensin converting enzyme [Enzymatic activity/volume] in Serum or Plasma
7
28
2.64
1.49
2.4
1.6
u/l
30.9
47.0
—
7
22
(3014111) Lactate [Moles/volume] in Serum or Plasma
10
46
2.34
1.47
44.6
8.1
mmol/l
1.1
1.2
—
10
46
(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection
5
16
3.26
1.46
2.0
1.5
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
28
190
1.73
1.43
12.5
3.7
—
—
—
0
0
(3003327) Ova and parasites identified in Stool by Light microscopy
6
23
2.73
1.39
1.8
1.3
—
—
—
0
0
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
34
246
1.66
1.37
2.4
2.1
pmol/l
99.9
92.7
0.36
21
136
(3019832) Treponema pallidum Ab [Presence] in Serum
13
70
2.02
1.33
1.4
1.8
—
—
—
0
0
(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells
5
18
2.89
1.30
1.8
1.9
—
—
—
0
0
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
34
249
1.64
1.29
4.9
4.3
ng/l
42.5
39.4
0.07
29
166
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
6
26
2.41
1.21
2.8
3.0
—
—
—
0
0
(3003396) Base excess in Arterial blood by calculation
13
74
1.90
1.15
33.3
7.5
mmol/l
0.8
1.3
—
8
57
(40768443) Skin Pathology biopsy report
5
21
2.47
1.10
1.0
1.1
—
—
—
0
0
(3016879) Cocaine [Presence] in Urine
0
29
0.00
1.00
0.0
1.4
—
—
—
0
0
(3027944) Amphetamines [Presence] in Urine
0
31
0.00
0.98
0.0
1.4
—
—
—
0
0
(3028300) Cannabinoids [Presence] in Urine
0
31
0.00
0.98
0.0
1.5
—
—
—
0
0
(3027008) Opiates [Presence] in Urine
0
31
0.00
0.98
0.0
1.5
—
—
—
0
0
(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma
0
32
0.00
0.97
0.0
1.4
—
—
—
0
0
(3000764) Benzodiazepines [Presence] in Urine
0
32
0.00
0.97
0.0
1.4
—
—
—
0
0
(3013512) EKG study
25
181
1.55
0.96
4.4
4.7
—
—
—
0
0
(3025941) Bacteria identified in Stool by Culture
8
43
1.95
0.90
1.6
1.1
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
21
148
1.57
0.90
4.2
2.7
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
10
57
1.86
0.88
14.0
3.7
—
—
—
0
0
(3019060) Gas panel - Arterial blood
8
46
1.82
0.85
6.6
4.3
—
—
—
0
0
(1001926) Buprenorphine [Presence] in Urine by Screen method
0
26
0.00
0.80
0.0
1.4
—
—
—
0
0
(3003785) Carcinoembryonic Ag [Mass/volume] in Serum or Plasma
11
70
1.66
0.69
6.9
4.4
ug/l
3.4
7.3
0.79
11
56
(40768804) Tissue Pathology biopsy report
30
241
1.39
0.66
2.2
1.9
—
—
—
0
0
(3002385) Erythrocyte distribution width [Ratio]
57
509
1.42
0.66
57.6
19.0
%
14.2
13.7
1.55
57
499
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
5
30
1.71
0.62
2.4
2.4
—
—
—
0
0
(3017895) Helicobacter pylori Ab [Units/volume] in Serum
0
20
0.00
0.61
0.0
1.6
—
—
—
0
0
(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture
0
20
0.00
0.61
0.0
1.6
—
—
—
0
0
(3050129) First trimester maternal screen panel - Serum or Plasma
0
22
0.00
0.60
0.0
1.2
—
—
—
0
0
(3011288) Drugs identified in Urine by Screen method
0
22
0.00
0.60
0.0
1.8
—
—
—
0
0
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
62
566
1.42
0.60
45.1
14.2
ml/min/173m2
61.2
82.2
4.87
53
451
(3019225) pH of Specimen
9
62
1.51
0.55
18.7
4.8
—
—
—
0
0
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
13
169
0.72
0.42
4.1
4.3
%
21.0
21.7
—
7
85
(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma
0
15
0.00
0.41
0.0
1.5
—
—
—
0
0
(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma
0
17
0.00
0.41
0.0
1.6
—
—
—
0
0
(44816559) Phosphatidylethanol [Mass/volume] in Blood
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
49
449
1.24
0.35
3.1
3.8
pmol/l
14.1
14.8
1.18
44
405
(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma
7
52
1.38
0.32
2.1
2.4
ug/l
3.9
5.9
—
7
45
(3000492) Spirometry study
7
54
1.32
0.31
1.1
1.3
—
—
—
0
0
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
66
630
1.27
0.28
52.6
15.0
mg/l
16.6
24.2
2.45
60
511
(3002256) Pathology report gross observation
10
77
1.34
0.27
1.3
1.3
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
46
427
1.18
0.25
3.9
3.3
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
6
80
0.73
0.25
1.0
1.3
—
—
—
0
0
(3007461) Platelets [#/volume] in Blood
67
694
0.79
0.25
66.5
22.3
e9/l
245.3
246.0
0.03
67
674
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
10
79
1.30
0.23
2.0
2.1
—
—
—
0
0
(3044889) 12 lead EKG panel
45
419
1.17
0.23
4.6
3.9
—
—
—
0
0
(3020564) Creatinine [Moles/volume] in Serum or Plasma
67
645
1.24
0.22
55.6
17.5
umol/l
143.7
78.5
5.57
67
645
(4010399)
5
42
1.20
0.22
1.2
1.3
—
—
—
0
0
(3005033) Fetal Nuchal fold Thickness US
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
(3043238) Trisomy 21 risk [Likelihood] in Fetus
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
(3047352) Trisomy 18 risk [Likelihood] in Fetus
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
(40768800) Prostate Pathology biopsy report
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(3038177) Helicobacter pylori Ab [Presence] in Serum
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
(4094501)
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
(3039443) Prostate specific Ag panel - Serum or Plasma
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
(3028707) Methadone [Presence] in Urine by Screen method
0
13
0.00
0.21
0.0
1.6
—
—
—
0
0
(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
(21494755) Public health laboratory ask at order entry panel
5
66
0.74
0.17
1.0
1.3
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
21
230
0.88
0.14
2.9
2.9
—
—
—
0
0
(3000963) Hemoglobin [Mass/volume] in Blood
68
695
0.86
0.12
65.6
22.4
g/l
125.5
134.5
4.01
68
681
(3010813) Leukocytes [#/volume] in Blood
68
695
0.86
0.12
65.5
22.3
e9/l
7.0
6.9
0.26
68
671
(3009542) Hematocrit [Volume Fraction] of Blood
58
563
1.11
0.10
46.7
15.8
%
38.2
39.7
0.89
41
405
(3024731) MCV [Entitic volume]
68
694
0.87
0.10
65.2
22.2
fl
91.5
91.0
0.38
68
683
(3035941) MCH [Entitic mass]
68
694
0.87
0.10
65.1
22.2
pg
30.3
30.3
0.08
68
683
(3026361) Erythrocytes [#/volume] in Blood
68
694
0.87
0.10
65.4
22.3
e12/l
4.2
4.5
3.02
68
670
(40761511) CBC panel - Blood by Automated count
63
644
0.90
0.09
48.8
14.4
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
18
166
1.11
0.08
1.4
1.5
—
—
—
0
0
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
13
143
0.89
0.08
1.2
1.2
u/ml
0.8
1.4
—
5
36
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
9
85
1.07
0.07
2.1
2.2
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
10
93
1.09
0.02
1.4
1.4
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
11
112
0.98
0.00
1.6
1.6
—
—
—
0
0
(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma
66
661
0.99
0.00
27.7
10.5
u/l
23.0
25.5
0.71
66
632
(3025547) Thyroglobulin Ab [Units/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
2.4
—
—
—
0
0
(3014271) Vancomycin [Susceptibility]
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3044242) Glucose [Moles/volume] in Arterial blood
0
7
0.00
0.00
0.0
1.9
—
—
—
0
0
(3025130) Human papilloma virus identified in Specimen
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
(3016914) Bacteria identified in Cerebral spinal fluid by Culture
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3008832) Norclozapine [Moles/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
13.4
—
1243.8
—
0
8
(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration
0
6
0.00
0.00
0.0
2.5
—
—
—
0
0
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
7
69
1.02
0.00
16.6
8.1
—
—
—
0
0
(3016616) Dehydroepiandrosterone sulfate (DHEA-S) [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.0
—
7.3
—
0
6
(3017569) Oxygen content in Arterial blood
0
7
0.00
0.00
0.0
1.9
—
—
—
0
0
(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3020717) Zinc [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.7
—
23.4
—
0
6
(3027953) Aldolase [Enzymatic activity/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.2
—
4.8
—
0
6
(3013327) Hepatitis A virus IgM Ab [Presence] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3046896) Herpes virus 6 DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3034603) RHD gene allele [Genotype] in Blood or Tissue by Molecular genetics method Nominal
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(3045066) Thymidine kinase [Enzymatic activity/volume] in Serum
0
5
0.00
0.00
0.0
1.4
—
9.0
—
0
5
(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3047007) Chlamydophila sp Ab [Presence] in Serum
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
2.0
—
0.8
—
0
5
(3000081) cloZAPine [Moles/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
14.8
—
2252.0
—
0
8
(3007821) Glucose [Moles/volume] in Serum or Plasma --baseline
0
5
0.00
0.00
0.0
1.0
—
6.5
—
0
5
(3006257) Acetylcholine receptor Ab [Moles/volume] in Serum
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3019601) Blood group antibody investigation [Interpretation] in Plasma or RBC
0
7
0.00
0.00
0.0
3.1
—
—
—
0
0
(4211845)
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3009340) Metanephrine [Moles/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood
0
6
0.00
0.00
0.0
4.2
—
—
—
0
0
(3032773) Endomysium IgG Ab [Titer] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood
0
6
0.00
0.00
0.0
4.2
—
—
—
0
0
(3024666) Lithium, Blood [Moles/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
7.3
—
0.7
—
0
9
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
5
52
0.96
0.00
1.4
1.9
—
—
—
0
0
(3022217) INR in Platelet poor plasma by Coagulation assay
7
78
0.89
0.00
50.9
25.7
—
1.1
—
0
10
(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection
5
49
1.02
0.00
1.6
1.9
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
5
55
0.90
0.00
1.2
1.1
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint N14_RAPIDPROGNEPHRITIC and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| N14_RAPIDPROGNEPHRITIC | 2.733 [1.89, 3.96] | < 0.001 |
| Birth year | 0.994 [0.98, 1.0] | 0.144 |
During the follow-up period (1.1.1998 — 31.12.2019), 78 out of 252 females with N14_RAPIDPROGNEPHRITIC died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| N14_RAPIDPROGNEPHRITIC | 3.037 [1.91, 4.83] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.004 |
During the follow-up period (1.1.1998 — 31.12.2019), 98 out of 231 males with N14_RAPIDPROGNEPHRITIC died.
Mortality risk
Mortality risk for people of age
years, who have N14_RAPIDPROGNEPHRITIC.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.228% | 0.493% |
| 5 | 1.488% | 3.599% |
| 10 | 3.874% | 8.098% |
| 15 | 7.352% | 15.216% |
| 20 | 12.18% | 24.741% |
Relationships between endpoints
↥Index endpoint: N14_RAPIDPROGNEPHRITIC – Rapidly progressive nephritic syndrome
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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