nephrotic syndrome: A collection of symptoms that include severe edema, proteinuria, and hypoalbuminemia; it is indicative of renal dysfunction.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1158 |
4. Check minimum number of eventsNone |
1158 |
5. Include endpointsNone |
1158 |
6. Filter based on genotype QC (FinnGen only) |
1158 |
Control definitions (FinnGen only)
- Control exclude
- N14_GLOMERULAR
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- N00-N08
- Name in latin
- Syndroma nephroticum
Similar endpoints
↥List of similar endpoints to
Nephrotic syndrome
based on the number of shared cases.
Similar with more cases:
- Glomerulonephritis
- Glomerular diseases
- Genitourinary diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 7991 | 3363 | 4520 |
| Only index persons | 6080 | 2628 | 3452 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.11 | 0.10 | 0.13 |
| Only index persons | 0.12 | 0.10 | 0.13 |
| Median age at first event (years) | |||
| Whole population | 50.10 | 49.08 | 50.66 |
| Only index persons | 45.52 | 43.36 | 47.16 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1158 | 494 | 664 |
| Unadjusted period prevalence (%) | 0.24 | 0.17 | 0.29 |
| Median age at first event (years) | 47.77 | 40.27 | 53.36 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1068
- Matched controls
- 10680
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
134.5
323.0
353
39
N04.9
ICD-10 Finland
Nephrotic syndrome, unspecified
+∞
323.0
489
*
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
90.4
320.4
349
57
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
204.2
295.5
296
20
C03CA01
ATC
furosemide; systemic
12.0
289.4
726
1606
A11CC03
ATC
alfacalcidol; systemic
63.3
270.1
312
69
L04AD01
ATC
ciclosporin; systemic
63.5
244.1
282
60
Z94.0
ICD-10 Finland
Kidney transplant status
153.5
240.4
248
21
N04.0
ICD-10 Finland
Nephrotic syndrome, minor glomerular abnormality
+∞
238.7
220
*
TK800
NOMESCO Finland
Hemodialysis
62.8
226.2
262
55
L04AA06
ATC
mycophenolic acid; systemic
63.4
215.3
249
51
N04.1
ICD-10 Finland
Nephrotic syndrome, focal and segmental glomerular lesions
+∞
215.1
199
*
A12AA04
ATC
calcium carbonate; oral
83.3
212.0
235
36
127
Kela drug reimbursment
Transplant complication
59.7
200.1
234
50
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
19.8
197.7
313
219
N04.2
ICD-10 Finland
Nephrotic syndrome, diffuse membranous glomerulonephritis
+∞
193.8
180
*
Z49.1
ICD-10 Finland
Extracorporeal dialysis
106.9
192.5
207
24
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
105.6
183.7
198
23
H02AB04
ATC
methylprednisolone; systemic
8.8
170.2
427
754
N18.8
ICD-10 Finland
Other chronic renal failure
33.3
169.4
225
85
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
159.6
168.0
174
13
B03XA02
ATC
darbepoetin alfa; parenteral
51.2
167.1
201
48
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
127.9
162.7
172
16
137
Kela drug reimbursment
Uraemia requiring dialysis
177.1
160.6
165
11
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
108.1
145.7
157
17
N18.0
ICD-10 Finland
End-stage renal disease
84.6
143.2
159
22
L04AA01
ATC
[U] ciclosporin; systemic
45.5
134.8
166
43
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
60.7
133.7
156
30
205
Kela drug reimbursment
Chronic hypertension
5.4
132.7
536
1674
R80
ICD-10 Finland
Isolated proteinuria
114.9
130.7
140
14
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
6.7
129.0
390
847
58199
ICD-8 Finland
Nephrotic syndrome
+∞
128.8
121
*
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
119.7
127.4
136
13
KA1AE
NOMESCO Finland
Kidney ultrasound examination
27.9
126.7
176
75
B05DA
ATC
Isotonic solutions
181.5
124.4
128
8
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
124.2
123.2
131
12
Z49.0
ICD-10 Finland
Preparatory care for dialysis
90.9
122.6
135
17
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
9.6
113.5
251
331
Z49.2
ICD-10 Finland
Other dialysis
185.6
112.8
116
7
C09AA02
ATC
enalapril; systemic
5.4
109.2
404
1087
B03XA01
ATC
erythropoietin; parenteral
66.6
107.8
124
21
N03.9
ICD-10 Finland
Chronic nephritic syndrome, unspecified
+∞
107.1
101
*
V03AE01
ATC
polystyrene sulfonate; oral
51.3
105.6
127
28
B05DB
ATC
Hypertonic solutions
164.3
100.1
104
7
C08CA01
ATC
amlodipine; oral
4.0
95.4
551
2233
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
13.1
95.3
175
157
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
4.2
95.1
483
1744
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
163.6
86.5
90
6
C02AC05
ATC
moxonidine; oral
12.3
85.8
162
153
N03.2
ICD-10 Finland
Chronic nephritic syndrome, diffuse membranous glomerulonephritis
+∞
85.6
81
*
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
157.6
83.4
87
6
ZX120
NOMESCO Finland
Intravenous
6.2
81.9
245
488
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
8.6
81.5
189
260
M04AA01
ATC
allopurinol; systemic
5.3
81.3
285
687
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
8.5
81.1
189
262
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
19.7
79.9
123
70
L04AX01
ATC
azathioprine; systemic
10.2
79.5
166
190
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
7.7
79.1
197
303
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
90.0
75.2
83
10
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
769.4
74.1
72
*
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
116.8
70.9
76
7
N03.1
ICD-10 Finland
Chronic nephritic syndrome, focal and segmental glomerular lesions
+∞
70.6
67
*
TK820
NOMESCO Finland
Peritoneal dialysis
115.1
69.8
75
7
N25.8
ICD-10 Finland
Other disorders resulting from impaired renal tubular function
83.0
69.1
77
10
N04.89
ICD-10 Finland
Nephrotic syndrome, other
+∞
68.5
65
*
N08.2*D89.80
ICD-10 Finland
Immunoglobulin A (IgA) nephropathy
+∞
68.5
65
*
N04.80
ICD-10 Finland
Congenital nephrotic syndrome of the Finnish type
+∞
68.5
65
*
5819X
ICD-9 Finland
Nephrotic syndrome with unspecified pathological lesion in kidney
+∞
67.4
64
*
V03AE03
ATC
lanthanum carbonate; oral
353.5
67.3
67
*
N39.1
ICD-10 Finland
Persistent proteinuria, unspecified
46.0
62.9
77
18
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
98.8
59.6
65
7
TPX10
NOMESCO Finland
Implantation of vascular injection port
11.0
59.3
117
118
N03.0
ICD-10 Finland
Chronic nephritic syndrome, minor glomerular abnormality
+∞
58.9
56
*
Z3231
NOMESCO Finland
Registered nurse
3.1
58.7
447
2021
N03.8
ICD-10 Finland
Chronic nephritic syndrome, other
+∞
57.8
55
*
V03AE02
ATC
sevelamer; oral
76.6
57.8
65
9
N19
ICD-10 Finland
Unspecified kidney failure
10.9
57.5
114
116
C08CA02
ATC
felodipine; oral
5.2
57.0
194
437
196
Kela drug reimbursment
Paricalcitol and cinacalcet
92.4
55.5
61
7
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.8
54.5
580
3201
TPH04
NOMESCO Finland
Cathetrisation of vein
3.3
53.9
336
1299
C10AA05
ATC
atorvastatin; oral
2.8
53.9
492
2466
H02AB09
ATC
hydrocortisone; systemic
10.3
53.7
109
116
WW200
NOMESCO Finland
Immunization
9.8
53.0
111
125
N03.3
ICD-10 Finland
Chronic nephritic syndrome, diffuse mesangial proliferative glomerulonephritis
+∞
50.4
48
*
C09CA01
ATC
losartan; oral
3.2
50.2
334
1342
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
4.3
49.9
205
556
N17.9
ICD-10 Finland
Acute renal failure, unspecified
8.6
49.7
112
143
N04.3
ICD-10 Finland
Nephrotic syndrome, diffuse mesangial proliferative glomerulonephritis
+∞
49.3
47
*
A12AA12
ATC
[U] calcium acetate anhydrous; systemic
167.3
46.2
48
*
3AC01
NOMESCO Finland
NA
24.6
45.9
65
28
L01AA01
ATC
cyclophosphamide; systemic
125.5
45.1
48
*
H05BX01
ATC
cinacalcet; oral
44.5
44.8
55
13
C02CA01
ATC
prazosin; oral
18.2
44.7
70
41
A49.9
ICD-10 Finland
Bacterial infection, unspecified
4.1
44.7
193
544
C08CA13
ATC
lercanidipine; oral
3.8
44.6
213
656
R4110
NOMESCO Finland
Physiotherapy
2.8
44.6
372
1711
Z99.2
ICD-10 Finland
Dependence on renal dialysis
122.8
44.1
47
*
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
16.9
43.6
70
44
B01AB10
ATC
tinzaparin; parenteral
5.5
43.0
136
277
58209
ICD-8 Finland
Chronic nephritis, Unspecified
+∞
43.0
41
*
Z2446
NOMESCO Finland
Social worker
4.4
43.0
170
440
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
4.7
41.7
152
362
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
4.3
41.1
166
438
Z3226
NOMESCO Finland
Physiotherapist
3.0
40.7
289
1186
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
5.8
40.2
121
232
PG5RT
NOMESCO Finland
PTA of arterio-venous shunt for dialysis
91.7
40.1
44
5
N08.39
ICD-10 Finland
Glomerular disorders in diabetes mellitus microalbuminuria
207.5
39.1
40
*
U14
ICPC
Kidney symptom/complaint
14.2
39.0
67
50
N06.9
ICD-10 Finland
Isolated proteinuria with specified morphological lesion, unspecified
+∞
38.8
37
*
321
Kela drug reimbursment
Paricalcitol and cinacalcet
44.6
38.4
47
11
PG5DE
NOMESCO Finland
Ultrasound examination of injection gate to artery or vein with Doppler method
87.4
38.1
42
5
TJA33
NOMESCO Finland
Percutaneous introduction of peritoneal dialysis catheter
202.2
38.1
39
*
RD210
NOMESCO Finland
NA
8.0
37.6
88
119
H02AB06
ATC
prednisolone; systemic
2.3
37.4
545
3310
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
4.4
37.3
147
377
TK810
NOMESCO Finland
Hemofiltration
32.0
37.3
49
16
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
37.7
37.1
47
13
PBL09
NOMESCO Finland
Construction of arteriovenous fistula from brachial artery
196.8
37.0
38
*
N04
ICD-10 Finland
Nephrotic syndrome
+∞
36.7
35
*
N04.5
ICD-10 Finland
Nephrotic syndrome, diffuse mesangiocapillary glomerulonephritis
+∞
36.7
35
*
K65.0
ICD-10 Finland
Acute peritonitis
15.4
36.2
60
41
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
7.8
36.2
86
119
N18.5
ICD-10 Finland
Chronic kidney disease, stage 5
191.4
36.0
37
*
C07AG02
ATC
carvedilol; oral
5.0
35.7
122
270
M10.9
ICD-10 Finland
Gout, unspecified
4.7
35.4
127
296
Z2221
NOMESCO Finland
Medical doctor
2.5
35.1
368
1876
ZXE10
NOMESCO Finland
More than one and less than three hours
2.3
35.1
446
2505
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
5.6
35.0
107
208
ZXD05
NOMESCO Finland
Urgent procedure
2.4
34.8
407
2194
N00.9
ICD-10 Finland
Acute nephritic syndrome, Unspecified
+∞
34.6
33
*
K06.18
ICD-10 Finland
Another gingival hyperplasia
30.0
34.5
46
16
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.9
34.2
243
986
ZXA00
NOMESCO Finland
Right side
2.5
34.0
340
1684
KAS20
NOMESCO Finland
Allogenic transplantation of kidney from living donor
95.8
33.9
37
*
N00.0
ICD-10 Finland
Acute nephritic syndrome, Minor glomerular abnormality
+∞
33.5
32
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.8
33.5
152
442
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.4
33.4
354
1806
I10
ICD-10 Finland
Essential (primary) hypertension
2.2
33.1
606
4002
7151
FHL
Kidney transplantation
175.4
32.9
34
*
ZXA05
NOMESCO Finland
Left side
2.5
32.7
314
1513
N05.9
ICD-10 Finland
Unspecified nephritic syndrome, unspecified
+∞
32.5
31
*
5813A
ICD-9 Finland
Nephrotic syndrome, With lesion of minimal change glomerulonephritis
+∞
32.5
31
*
KAC00
NOMESCO Finland
Nephrectomy
33.6
32.4
42
13
M05BA04
ATC
alendronic acid; oral
4.5
32.3
121
294
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
10.4
32.2
64
65
R50.9
ICD-10 Finland
Fever, unspecified
2.9
32.0
231
942
ZXE00
NOMESCO Finland
One hour or less
2.2
31.4
483
2923
N03.5
ICD-10 Finland
Chronic nephritic syndrome, diffuse mesangiocapillary glomerulonephritis
+∞
31.4
30
*
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
7.2
30.6
76
112
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
3.2
30.6
181
645
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
4.3
30.5
121
310
R4190
NOMESCO Finland
Nutritional therapy
4.8
30.3
107
244
C07AB02
ATC
metoprolol; systemic
2.6
30.1
264
1205
C09CA06
ATC
candesartan; oral
2.6
30.0
270
1249
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
8.8
29.4
64
77
I12.0
ICD-10 Finland
Hypertensive renal disease with renal failure
23.0
29.3
42
19
N04.4
ICD-10 Finland
Nephrotic syndrome, diffuse endocapillary proliferative glomerulonephritis
+∞
29.3
28
*
N08.2
ICD-10 Finland
Glomerular disorders in blood diseases and disorders involving the immune mechanism
+∞
29.3
28
*
ZXE20
NOMESCO Finland
More than three and less than five hours
2.9
28.9
202
803
ZST00
NOMESCO Finland
Procedure related to previous procedure classified in chapter T
106.3
28.8
31
*
D89.80
ICD-10 Finland
Immunoglobulin A (IgA) deposits in organisms
+∞
28.2
27
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.3
28.0
347
1878
I50.9
ICD-10 Finland
Heart failure, unspecified
3.0
28.0
176
652
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.6
28.0
237
1056
J01FF01
ATC
clindamycin; systemic
2.3
27.4
332
1773
N08.5*M32.1
ICD-10 Finland
Glomerular disorders in systemic lupus erythematosus
+∞
27.2
26
*
A41.9
ICD-10 Finland
Sepsis, unspecified
5.6
27.1
81
153
C10AA04
ATC
fluvastatin; oral
3.6
27.0
132
406
RS220
NOMESCO Finland
NA
9.8
27.0
55
59
C02EA02
ATC
NA
5.3
26.8
84
168
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
5.2
26.8
86
177
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
6.3
26.8
73
123
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
3.2
26.7
154
536
WX892
NOMESCO Finland
Monitored bed care
3.5
26.5
133
417
KBV00
NOMESCO Finland
Insertion of stent into ureter
30.1
26.4
35
12
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
4.3
26.4
102
255
R60.9
ICD-10 Finland
Oedema, unspecified
5.1
25.9
85
179
PBM10
NOMESCO Finland
Closure of arteriovenous fistula of radial artery
138.4
25.7
27
*
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
3.4
25.5
135
441
B01AA03
ATC
warfarin; systemic
2.4
25.3
249
1193
WX002
NOMESCO Finland
Sedation and analgesia
2.4
25.1
241
1139
N00.2
ICD-10 Finland
Acute nephritic syndrome, Diffuse membranous glomerulonephritis
+∞
25.1
24
*
K00.40
ICD-10 Finland
Postnatal enamel hypoplasia
11.4
25.0
47
43
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
7.6
25.0
59
81
1XC02
NOMESCO Finland
NA
20.1
24.9
37
19
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
6.0
24.9
70
123
TK824
NOMESCO Finland
Replacement of peritoneal dialysis catheter extension tube
133.1
24.7
26
*
ZXD10
NOMESCO Finland
Scheduled procedure
2.0
24.4
435
2714
D64.9
ICD-10 Finland
Anaemia, unspecified
3.1
24.2
143
505
C07AB07
ATC
bisoprolol; oral
2.0
24.1
486
3178
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
6.1
24.1
67
116
OAB74
NOMESCO Finland
Nutritional guidance related to treatment and rehabilitation for medical condition
23.4
24.0
34
15
7910X
ICD-9 Finland
Nonspecific findings on examination of urine, Proteinuria[PROTEINURIA NUD]
69.1
23.9
27
*
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
4.5
23.9
87
205
WW500
NOMESCO Finland
Blood transfusion
4.8
23.8
82
182
A46
ICD-10 Finland
Erysipelas
2.7
23.8
186
785
L04AA05
ATC
[U] tacrolimus; systemic
127.9
23.7
25
*
R60.0
ICD-10 Finland
Localized oedema
3.0
23.4
145
527
J01MA12
ATC
levofloxacin; systemic
2.4
23.4
231
1106
H3603, E103
ICD-10 Finland
NA
13.4
23.0
40
31
A10AE04
ATC
insulin glargine; parenteral
3.1
23.0
136
480
5818X
ICD-9 Finland
Nephrotic syndrome, With other specified pathological lesion in kidney
+∞
23.0
22
*
H02AB07
ATC
prednisone; oral
2.6
23.0
182
773
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.2
22.9
127
428
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
10.6
22.7
44
43
E87.5
ICD-10 Finland
Hyperkalaemia
10.6
22.7
44
43
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
3.3
22.7
120
391
XF400
NOMESCO Finland
ECG with 12 standard connections
2.4
22.5
227
1096
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.2
22.3
283
1522
C10AA01
ATC
simvastatin; oral
1.9
22.1
441
2840
5828A
ICD-9 Finland
Chronic glomerulonephritis, With other specified pathological lesion in kidney[GLOMERULONEPHRITIS CHRONICA ALIA DEF,EI NEFR SDR]
+∞
21.9
21
*
7101
FHL
Needle biopsy in the operating room
+∞
21.9
21
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.4
21.7
214
1019
V03AE04
ATC
calcium acetate and magnesium carbonate; systemic
117.4
21.6
23
*
N28.9
ICD-10 Finland
Disorder of kidney and ureter, unspecified
44.3
21.5
26
6
K06.19
ICD-10 Finland
Gingival hyperplasia UNS
23.7
21.3
30
13
XPX08
NOMESCO Finland
Intraoperative flow measurement
15.0
21.3
35
24
N02AX02
ATC
tramadol; systemic, rectal
1.9
21.2
441
2876
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
4.7
21.0
73
164
Z94.9
ICD-10 Finland
Transplanted organ and tissue status, unspecified
61.3
20.9
24
*
TK823
NOMESCO Finland
Peritoneal permeability analysis
+∞
20.9
20
*
TJW99
NOMESCO Finland
Other minor procedure in gastrointestinal endoscopy
78.4
20.7
23
*
A02BC01
ATC
omeprazole; systemic
2.1
20.7
302
1714
C03AA03
ATC
hydrochlorothiazide; oral
3.1
20.7
121
422
TPH07
NOMESCO Finland
Cathetrisation of artery
2.7
20.6
150
604
WX203
NOMESCO Finland
Infraclavicular plexus blockade
7.2
20.6
50
72
ZX108
NOMESCO Finland
Inhalation
11.5
20.6
38
34
M01AE01
ATC
ibuprofen; systemic, rectal
0.5
20.6
640
7899
78900
ICD-8 Finland
Abnormal urinary constituents of unspecified cause, Albuminuria
42.6
20.5
25
6
ZYB02
NOMESCO Finland
Outreach service at unit of another specialty
14.6
20.4
34
24
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.3
20.1
221
1106
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
27.6
20.1
27
10
R60.1
ICD-10 Finland
Generalized oedema
19.3
20.0
30
16
M10.3
ICD-10 Finland
Gout due to impairment of renal function
23.9
20.0
28
12
I15.0
ICD-10 Finland
Renovascular hypertension
23.9
20.0
28
12
ZXA10
NOMESCO Finland
Bilateral
2.3
20.0
218
1086
KA9AE
NOMESCO Finland
Ultrasound examination transplanted kidney
58.7
20.0
23
*
BBA40
NOMESCO Finland
Subtotal parathyroidectomy
36.5
19.9
25
7
N08.4*E85.9
ICD-10 Finland
Glomerular disorders in amyloidosis
+∞
19.8
19
*
N08.5
ICD-10 Finland
Glomerular disorders in systemic connective tissue disorders
+∞
19.8
19
*
J01MA14
ATC
moxifloxacin; systemic
3.0
19.8
121
434
PBU84
NOMESCO Finland
Plastic repair of arteriovenous fistula from artery of upper extremity
74.9
19.8
22
*
H26.3
ICD-10 Finland
Drug-induced cataract
16.8
19.7
31
19
PG5AC
NOMESCO Finland
Contrast examination of injection gate to artery or vein
203.6
19.6
20
*
A02BC02
ATC
pantoprazole; systemic
1.8
19.5
641
4829
B07.9
ICD-10 Finland
Verruca simplex
4.6
19.3
68
155
103
Kela drug reimbursment
Diabetes, insulin-treated
2.0
19.2
288
1642
NHQ40
NOMESCO Finland
Amputation of toe
9.6
19.2
39
42
C03DA01
ATC
spironolactone; oral
2.7
19.1
138
552
A10AA01
ATC
NA
5.6
19.1
56
104
XF602
NOMESCO Finland
Bloodpressure monitoring
9.0
19.0
40
46
XCK10
NOMESCO Finland
Photography of fundus of eye
2.8
18.9
132
517
T86.1
ICD-10 Finland
Kidney transplant failure and rejection
71.2
18.8
21
*
A12BA01
ATC
potassium chloride; oral
4.3
18.7
70
170
PB1AC
NOMESCO Finland
Angiography of upper extremity with X-ray
101.8
18.6
20
*
U88
ICPC
Glomerulonephritis/nephrosis
193.2
18.6
19
*
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
2.1
18.5
243
1308
602
Kela drug reimbursment
Children's severe malnutrition
8.4
18.3
40
49
4AA09
NOMESCO Finland
NA
44.8
18.3
22
5
PG1XE
NOMESCO Finland
Other ultrasound examination of blood vessel not elsewhere classified
22.2
18.2
26
12
EBA15
NOMESCO Finland
Extraction of large number of teeth
4.2
18.2
71
179
WX202
NOMESCO Finland
Supraclavicular plexus blockade
8.0
18.2
41
53
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
3.8
18.1
78
215
WX204
NOMESCO Finland
Axillary plexus blockaced
5.4
18.1
55
107
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.9
18.0
77
211
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.8
17.9
77
212
E85.9
ICD-10 Finland
Amyloidosis, unspecified
67.8
17.8
20
*
5829A
ICD-9 Finland
Chronic glomerulonephritis with unspecified pathological lesion in kidney[GLOMERULONEPHRITIS CHRONICA NUD ,EI NEFR SDR]
+∞
17.8
17
*
58200
ICD-8 Finland
Chronic nephritis, Cum uraemia
+∞
17.8
17
*
306
Kela drug reimbursment
Erythropoietin and darbepoetin
29.3
17.5
23
8
WX882
NOMESCO Finland
High dependency care
3.8
17.4
76
212
RJ411
NOMESCO Finland
NA
24.5
17.4
24
10
J01DB01
ATC
cefalexin; oral
1.9
17.3
846
7114
L01BB01
ATC
NA
42.7
17.3
21
5
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.0
17.1
242
1339
C08CA05
ATC
nifedipine; systemic
3.2
17.1
91
298
3025
Kela drug reimbursment
Calcium carbonate
50.9
17.0
20
*
A10AA02
ATC
NA
4.6
17.0
59
133
PB1DE
NOMESCO Finland
Upper extremity arteries ultrasound examination with Doppler method
22.3
16.9
24
11
SAA04
NOMESCO Finland
Special inverstigation of mouth
3.3
16.8
88
284
Z3229
NOMESCO Finland
Other healthcare associate professional
2.7
16.7
124
503
5828B
ICD-9 Finland
Chronic glomerulonephritis, With other specified pathological lesion in kidney[GLOMERULONEPHRITIS CHRONICA ALIA DEF,NEFR SDR]
+∞
16.7
16
*
N06.1
ICD-10 Finland
Isolated proteinuria with specified morphological lesion, focal and segmental glomerular lesions
+∞
16.7
16
*
5AB14
NOMESCO Finland
NA
20.4
16.5
24
12
212
Kela drug reimbursment
Gout
7.0
16.3
40
59
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.0
16.3
242
1366
C08CA03
ATC
isradipine; systemic
9.0
16.3
34
39
J01MA02
ATC
ciprofloxacin; systemic
1.8
16.3
398
2674
WX610
NOMESCO Finland
Patient controlled analgesia
18.9
16.0
24
13
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.8
16.0
361
2359
A10AB04
ATC
insulin lispro; parenteral (insulins and analog. for injection, fast-acting)
4.3
15.9
60
147
WW400
NOMESCO Finland
Plasmaferesis
33.9
15.8
20
6
N06.0
ICD-10 Finland
Isolated proteinuria with specified morphological lesion, minor glomerular abnormality
+∞
15.7
15
*
TKA00
NOMESCO Finland
Needle biopsy of kidney or pelvis of kidney
+∞
15.7
15
*
RS222
NOMESCO Finland
NA
7.3
15.6
37
52
N11.9
ICD-10 Finland
Chronic tubulo-interstitial nephritis, unspecified
26.7
15.6
21
8
D638, N188
ICD-10 Finland
NA
86.4
15.6
17
*
KAB00
NOMESCO Finland
Biopsy of kidney or pelvis of kidney
86.4
15.6
17
*
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
11.0
15.5
29
27
A10AE05
ATC
insulin detemir; parenteral
3.1
15.3
86
291
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
5.5
15.3
45
85
N25.0
ICD-10 Finland
Renal osteodystrophy
23.8
15.1
21
9
EB1WA
NOMESCO Finland
NA
20.4
15.1
22
11
JN3AD
NOMESCO Finland
Abdominal CT examination
2.8
15.1
99
371
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
3.1
15.0
86
297
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
5.5
14.9
44
83
WX402
NOMESCO Finland
General anaesthesia
2.0
14.9
201
1087
B01AB05
ATC
enoxaparin; parenteral
1.8
14.7
292
1820
UJF32
NOMESCO Finland
Coloscopy
1.9
14.7
256
1523
RS221
NOMESCO Finland
NA
6.7
14.7
37
57
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.7
14.6
101
392
KAS96
NOMESCO Finland
Other transplantation of kidney or related procedure
+∞
14.6
14
*
Z94.4
ICD-10 Finland
Liver transplant status
14.4
14.6
24
17
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.9
14.5
260
1564
6112
FHL
Installation of a peritoneal dialysis or lavage catheter in an operating room
152.0
14.5
15
*
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.9
14.5
251
1489
M10
ICD-10 Finland
Gout
3.7
14.4
63
177
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.5
14.3
118
506
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
2.5
14.3
116
495
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.4
14.1
123
544
M10.0
ICD-10 Finland
Idiopathic gout
4.3
14.1
52
125
K05.31
ICD-10 Finland
Periodontitis pronounced
2.6
14.1
108
446
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
4.6
14.1
48
107
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.6
14.0
110
459
I15.9
ICD-10 Finland
Secondary hypertension, unspecified
11.6
13.8
25
22
58399
ICD-8 Finland
Nephritis, unqualified
+∞
13.6
13
*
58099
ICD-8 Finland
Acute nephritis
+∞
13.6
13
*
6119
FHL
Other measure in this category
+∞
13.6
13
*
N06.2
ICD-10 Finland
Isolated proteinuria with specified morphological lesion, diffuse membranous glomerulonephritis
+∞
13.6
13
*
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
9.0
13.5
28
32
NHQ30
NOMESCO Finland
Amputation of foot, transmetatarsal
34.5
13.5
17
5
I15.8
ICD-10 Finland
Other secondary hypertension
34.5
13.5
17
5
BE00A
NOMESCO Finland
NA
141.7
13.5
14
*
TKA05
NOMESCO Finland
Aspiration cytology of kidney
141.7
13.5
14
*
B25.9
ICD-10 Finland
Cytomegaloviral disease, unspecified
26.1
13.4
18
7
XF600
NOMESCO Finland
Bloodpressure measurement
2.6
13.3
100
409
E11.5
ICD-10 Finland
Type 2 diabetes mellitus, with peripheral circulatory complications
6.2
13.3
35
58
K65.9
ICD-10 Finland
Peritonitis, unspecified
40.6
13.2
16
*
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
5.5
13.1
38
71
V03AG01
ATC
sodium cellulose phosphate; systemic
17.0
13.0
20
12
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.7
13.0
416
2971
C09BA02
ATC
enalapril and diuretics; systemic
2.6
12.8
97
397
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.0
12.8
180
987
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.1
12.7
158
824
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
4.9
12.7
41
87
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
5.6
12.6
36
66
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.3
12.6
118
541
B01AB04
ATC
dalteparin; parenteral
3.2
12.5
67
221
5821B
ICD-9 Finland
Chronic glomerulonephritis, With lesion of membranous glomerulonephritis[GLOMERULONEPHRITIS CHRONICA MEMBRANACEA,NEFR SDR]
+∞
12.5
12
*
N03.4
ICD-10 Finland
Chronic nephritic syndrome, diffuse endocapillary proliferative glomerulonephritis
+∞
12.5
12
*
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
5.2
12.5
38
75
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.8
12.4
278
1787
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
3.5
12.3
58
174
XW000
NOMESCO Finland
Bone marrow biopsy
3.4
12.3
60
185
JN4AD
NOMESCO Finland
Body CT examination
2.5
12.3
97
407
A10BH05
ATC
linagliptin; oral
3.4
12.3
59
180
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
6.8
12.3
30
45
C09CA03
ATC
valsartan; oral
2.5
12.2
102
440
RJ420
NOMESCO Finland
NA
16.1
12.2
19
12
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
4.2
12.1
45
110
E10.5
ICD-10 Finland
Type 1 diabetes mellitus, With peripheral circulatory complications
18.3
12.1
18
10
B25.8
ICD-10 Finland
Other cytomegaloviral diseases
27.0
12.1
16
6
N18
ICD-10 Finland
Chronic kidney disease
9.4
12.0
24
26
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
4.8
11.7
38
81
M32.1
ICD-10 Finland
Systemic lupus erythematosus with organ or system involvement
65.7
11.6
13
*
A08
ICPC
Swelling
3.6
11.6
51
145
K00.41
ICD-10 Finland
Prenatal enamel hypoplasia
19.2
11.6
17
9
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.5
11.6
95
405
PBM09
NOMESCO Finland
Closure of arteriovenous fistula of brachial artery
+∞
11.5
11
*
N08.4
ICD-10 Finland
Glomerular disorders in other endocrine, nutritional and metabolic diseases
+∞
11.5
11
*
N05.8
ICD-10 Finland
Unspecified nephritic syndrome, other
+∞
11.5
11
*
B05D
ATC
PERITONEAL DIALYTICS
+∞
11.5
11
*
D638, N180
ICD-10 Finland
NA
121.3
11.4
12
*
4019X
ICD-9 Finland
Essential hypertension, Unspecified
4.4
11.4
40
93
TQW99
NOMESCO Finland
Other minor procedure on skin
3.1
11.4
64
217
PB1BC
NOMESCO Finland
Extensive angiography of upper extremity with X-ray
35.4
11.3
14
*
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
9.7
11.3
22
23
SAA03
NOMESCO Finland
Extended examination of mouth
1.6
11.3
403
2936
T89
ICPC
Diabetes insulin dependent
3.3
11.2
56
177
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
3.5
11.1
52
156
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.7
11.1
48
135
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
9.3
11.0
22
24
SPAT1255
SPAT
Intravenous administration of medicine
2.6
10.9
79
316
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.3
10.9
107
502
N17.0
ICD-10 Finland
Acute renal failure with tubular necrosis
12.1
10.9
19
16
GD1LA
NOMESCO Finland
GD
6.6
10.8
27
42
WZC30
NOMESCO Finland
Teaching
2.0
10.8
143
764
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
3.0
10.8
61
208
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.3
10.8
99
450
1AB02
NOMESCO Finland
NA
18.0
10.7
16
9
RJ414
NOMESCO Finland
NA
28.3
10.7
14
5
N17.8
ICD-10 Finland
Other acute renal failure
7.6
10.7
24
32
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.6
10.7
79
321
C10AX09
ATC
ezetimibe; oral
2.2
10.7
117
576
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
3.5
10.6
48
140
KAS40
NOMESCO Finland
Excision of transplanted kidney
60.6
10.6
12
*
I11.9
ICD-10 Finland
Hypertensive heart disease without (congestive) heart failure
3.2
10.6
54
173
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
7.1
10.6
25
36
Q61.2
ICD-10 Finland
Polycystic kidney, autosomal dominant
11.4
10.6
19
17
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.6
10.5
77
310
A10BB12
ATC
glimepiride; oral
2.5
10.5
80
331
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
3.5
10.4
47
137
TK830
NOMESCO Finland
Ultrafiltration
+∞
10.4
10
*
5820A
ICD-9 Finland
Chronic glomerulonephritis, With lesion of proliferative glomerulonephritis[GLOMERULONEPHRITIS CHRONICA PROLIF,EI NEFR SDR]
+∞
10.4
10
*
TJA30
NOMESCO Finland
Peritoneal dialysis
+∞
10.4
10
*
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.4
10.4
89
392
PG1AE
NOMESCO Finland
Ultrasound examination of artery not elsewher classified
12.2
10.4
18
15
M01AH05
ATC
etoricoxib; oral
0.6
10.3
313
4212
GD1AD
NOMESCO Finland
Thorax CT examination
3.0
10.3
59
204
PD4DE
NOMESCO Finland
Lower extremity artery ultrasound examination with Doppler method
5.6
10.3
29
53
NA3SA
NOMESCO Finland
Lumbar spine X-ray examination in standing position
10.7
10.3
19
18
UKC02
NOMESCO Finland
Cystoscopy
1.9
10.2
169
980
S97
ICPC
Chronic ulcer skin
2.9
10.2
60
213
Z63.7
ICD-10 Finland
Other stressful life events affecting family and household
4.1
10.1
38
95
RS121
NOMESCO Finland
NA
8.5
10.1
21
25
D63.8
ICD-10 Finland
Anaemia in other chronic diseases classified elsewhere
14.7
10.0
16
11
3A013
NOMESCO Finland
NA
40.5
10.0
12
*
K06.10
ICD-10 Finland
Gingival fibromatosis
40.5
10.0
12
*
A41.8
ICD-10 Finland
Other specified sepsis
5.0
10.0
31
64
WX110
NOMESCO Finland
Local anesthesy
1.5
9.9
676
5669
NGQ20
NOMESCO Finland
Amputation of lower leg
12.3
9.9
17
14
UJF30
NOMESCO Finland
Ileoscopy through colon
2.2
9.9
98
463
H3600, E103
ICD-10 Finland
NA
8.2
9.9
21
26
R06.0
ICD-10 Finland
Dyspnoea
1.7
9.8
232
1501
ZX112
NOMESCO Finland
Subcutaneous
4.3
9.8
35
83
F59
ICD-10 Finland
Unspecified behavioural syndromes associated with physiological disturbances and physical factors
26.3
9.8
13
5
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
5.9
9.7
26
45
E0000UV
ATC
NA
1.5
9.7
383
2836
K65.8
ICD-10 Finland
Other peritonitis
55.5
9.7
11
*
3XA02
NOMESCO Finland
NA
55.5
9.7
11
*
BC00A
NOMESCO Finland
NA
55.5
9.7
11
*
M01AB05
ATC
diclofenac; systemic, rectal
0.7
9.6
412
5202
D47.2
ICD-10 Finland
Monoclonal gammopathy of undetermined significance (MGUS)
7.9
9.6
21
27
A41.1
ICD-10 Finland
Sepsis due to other specified staphylococcus
10.1
9.5
18
18
PA6AE
NOMESCO Finland
Ulrasound examination of neck vasculature
7.2
9.5
22
31
5850A
ICD-9 Finland
Chronic renal failure[INSUFFICIENTIA RENIS CHRONICA SINE URAEMIA]
100.9
9.4
10
*
PB1AE
NOMESCO Finland
Ultrasound examination of arteries of upper extremity
100.9
9.4
10
*
H3601, E113
ICD-10 Finland
NA
6.3
9.4
24
39
R77.0
ICD-10 Finland
Abnormality of albumin
30.3
9.4
12
*
PBU81
NOMESCO Finland
Thrombectomy in arteriovenous fistula from artery of upper extremity
+∞
9.4
9
*
N08.5*M31.3
ICD-10 Finland
Glomerular disorders in Wegener's granulomatosis
+∞
9.4
9
*
4059B
ICD-9 Finland
Secondary hypertension, Unspecified[HYPERTONIA SECUNDARIA ALIA DEFINITA]
+∞
9.4
9
*
N00.1
ICD-10 Finland
Acute nephritic syndrome, Focal and segmental glomerular lesions
+∞
9.4
9
*
BBA50
NOMESCO Finland
Total parathyroidectomy
+∞
9.4
9
*
5604
FHL
Vascular preparation or cannulation in the operating room
21.9
9.4
13
6
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.8
9.3
180
1094
C09AA05
ATC
ramipril; oral
1.7
9.3
230
1506
QCB10
NOMESCO Finland
Major dressing of wound of skin of upper limb
4.1
9.2
34
84
O12.1
ICD-10 Finland
Gestational proteinuria
13.8
9.2
15
11
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
2.7
9.2
62
240
M13.9
ICD-10 Finland
Arthritis, unspecified
2.4
9.1
74
316
6BA02
NOMESCO Finland
NA
11.6
9.1
16
14
WX213
NOMESCO Finland
Lower leg blockade
9.1
9.0
18
20
C08DB01
ATC
diltiazem; oral
2.8
9.0
58
218
IGY02
NOMESCO Finland
Psychiatric monitoring contact
3.4
9.0
43
132
RJ120
NOMESCO Finland
NA
37.0
9.0
11
*
C09CA07
ATC
telmisartan; oral
2.4
8.9
76
332
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
2.9
8.9
53
190
R11
ICD-10 Finland
Nausea and vomiting
2.2
8.9
91
436
SPAT1262
SPAT
Handing over of treatment supplies
1.7
8.9
182
1125
C10AA03
ATC
pravastatin; oral
2.3
8.8
78
347
Z96.1
ICD-10 Finland
Presence of intraocular lens
2.0
8.8
110
573
E86
ICD-10 Finland
Volume depletion
4.1
8.8
33
83
H43.1
ICD-10 Finland
Vitreous haemorrhage
3.8
8.8
36
98
H25.1
ICD-10 Finland
Senile nuclear cataract
1.7
8.8
195
1236
A08.4
ICD-10 Finland
Viral intestinal infection, unspecified
2.8
8.7
53
193
5602
FHL
Internal fistula (eg Cimino)
50.4
8.7
10
*
H05BX02
ATC
paricalcitol; systemic
50.4
8.7
10
*
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
3.9
8.7
34
89
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
5.1
8.7
26
52
K07
ICPC
Swollen ankles/oedema
3.1
8.6
45
148
H04AA01
ATC
glucagon; nasal, parenteral
3.3
8.6
41
126
R04.0
ICD-10 Finland
Epistaxis
2.3
8.6
75
334
QDG20
NOMESCO Finland
Operation for chronic ulcer or fistula of skin of lower limb
8.3
8.6
18
22
H3601, E103
ICD-10 Finland
NA
7.0
8.6
20
29
A49.8
ICD-10 Finland
Other bacterial infections of unspecified site
10.1
8.5
16
16
B01AC04
ATC
clopidogrel; oral
1.8
8.5
150
884
N02AA05
ATC
oxycodone; systemic
1.9
8.5
136
775
E66.00
ICD-10 Finland
Metabolic syndrome
2.6
8.5
62
251
ZZA00
NOMESCO Finland
Split skin graft
3.7
8.5
35
96
5850B
ICD-9 Finland
Chronic renal failure[INSUFFICIENTIA RENIS CHRONICA CUM URAEMIA]
27.7
8.5
11
*
QXA20
NOMESCO Finland
Skin abrasion, unspecified location
20.2
8.5
12
6
PD4AC
NOMESCO Finland
Arterigography of lower extremity with X-ray
5.7
8.5
23
41
R4180
NOMESCO Finland
Podiatric therapy
7.4
8.5
19
26
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.0
8.4
103
531
73410
ICD-8 Finland
Diffuse diseases of connective tissue, Systemic lupus erythematosus
90.7
8.4
9
*
TKC20
NOMESCO Finland
Catheterisation of bladder
2.3
8.4
75
335
A10BH02
ATC
vildagliptin; oral
4.9
8.4
26
54
I50.0
ICD-10 Finland
Congestive heart failure
2.3
8.4
73
325
N0830, E102
ICD-10 Finland
NA
+∞
8.3
8
*
5829B
ICD-9 Finland
Chronic glomerulonephritis with unspecified pathological lesion in kidney[GLOMERULONEPHRITIS CHRONICA NUD ,NEFR SDR]
+∞
8.3
8
*
PG5ST
NOMESCO Finland
Endovascular thrombolysis of arterio-venous shunt for dialysis with radiological guidance
+∞
8.3
8
*
JLE03
NOMESCO Finland
Allogenic total transplantation of pancreas with pancreaticoenterostomy
+∞
8.3
8
*
N00.5
ICD-10 Finland
Acute nephritic syndrome, Diffuse mesangiocapillary glomerulonephritis
+∞
8.3
8
*
7155
FHL
Exploration of the graft
+∞
8.3
8
*
RS321
NOMESCO Finland
NA
+∞
8.3
8
*
187
Kela drug reimbursment
MPA
+∞
8.3
8
*
S18
ICPC
Laceration/cut
1.5
8.2
386
2941
E11.3
ICD-10 Finland
Type 2 diabetes mellitus, with ophthalmic complications
3.7
8.2
34
94
H26.2
ICD-10 Finland
Complicated cataract
5.2
8.2
24
47
C09AA03
ATC
lisinopril; oral
2.7
8.2
53
201
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
3.3
8.2
40
126
A06AD11
ATC
lactulose; oral
1.8
8.2
133
763
R63.8
ICD-10 Finland
Other symptoms and signs concerning food and fluid intake
11.8
8.1
14
12
XF612
NOMESCO Finland
Measurement of central venous pressure
17.3
8.1
12
7
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.6
8.0
56
222
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
4.4
8.0
27
62
D64.8
ICD-10 Finland
Other specified anaemias
4.4
8.0
27
62
J01CA04
ATC
amoxicillin; systemic
1.5
7.9
803
7131
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
2.9
7.9
46
163
RJ410
NOMESCO Finland
NA
13.1
7.9
13
10
C02DE02
ATC
NA
5.8
7.9
21
37
A10AD05
ATC
insulin aspart; parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)
4.7
7.8
25
54
J01EA01
ATC
trimethoprim; systemic
1.6
7.8
197
1292
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
2.3
7.8
74
341
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
3.5
7.8
34
98
QDB99
NOMESCO Finland
Other procedure for wound of skin of lower limb
8.5
7.8
16
19
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.4
7.8
63
268
E000003
ATC
NA
2.6
7.8
55
220
CKC15
NOMESCO Finland
Panretinal photocoagulation
7.0
7.8
18
26
M04AA03
ATC
febuxostat; oral
15.1
7.7
12
8
KH1YT
NOMESCO Finland
Percutaneous implantation of endoprothesis with radiological guidance
15.1
7.7
12
8
J01CF02
ATC
cloxacillin; systemic
4.1
7.7
28
69
A07AA09
ATC
vancomycin; oral
5.6
7.7
21
38
N02BE01
ATC
paracetamol; systemic, rectal
1.5
7.6
806
7179
C90.0
ICD-10 Finland
Multiple myeloma
8.1
7.6
16
20
K05.10
ICD-10 Finland
Gingivitis (chronic) NOS
1.8
7.6
125
721
H35.0
ICD-10 Finland
Background retinopathy and retinal vascular changes
11.9
7.6
13
11
SCD02
NOMESCO Finland
Removal of tooth plaque or tartar
8.9
7.6
15
17
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.9
7.5
119
676
K03.00
ICD-10 Finland
Approximal wear
2.6
7.5
53
212
ZX199
NOMESCO Finland
Other rote
7.2
7.5
17
24
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
2.0
7.4
94
493
SBB00
NOMESCO Finland
Fotograf of mouth and teeth
2.7
7.4
48
182
H03AA01
ATC
levothyroxine sodium; systemic
1.6
7.4
184
1201
JAB00
NOMESCO Finland
Division and ligature of inguinal hernia sac
7.7
7.4
16
21
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
7.7
7.4
16
21
JN2AE
NOMESCO Finland
Ultrasound examination of lower part of abdomen without contrast
6.0
7.4
19
32
288
Kela drug reimbursment
Febuxostat
13.5
7.4
12
9
A02BA02
ATC
ranitidine; systemic
1.7
7.4
167
1061
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
7.3
202
1354
ZXE30
NOMESCO Finland
More than five and less than seven hours
2.3
7.3
63
278
R31
ICD-10 Finland
Unspecified haematuria
1.9
7.3
99
533
ZX100
NOMESCO Finland
Oral
5.0
7.3
22
45
Z940, N0480
ICD-10 Finland
NA
+∞
7.3
7
*
N06.8
ICD-10 Finland
Isolated proteinuria with specified morphological lesion, other
+∞
7.3
7
*
5839X
ICD-9 Finland
Nephritis and nephropathy, not specified as acute or chronic, With unspecified pathological lesion in kidney
+∞
7.3
7
*
N00.3
ICD-10 Finland
Acute nephritic syndrome, Diffuse mesangial proliferative glomerulonephritis
+∞
7.3
7
*
PB1AT
NOMESCO Finland
Upper extremity artery PTA
+∞
7.3
7
*
N0480, Z940
ICD-10 Finland
NA
+∞
7.3
7
*
N083, E102
ICD-10 Finland
NA
+∞
7.3
7
*
E85.3
ICD-10 Finland
Secondary systemic amyloidosis
+∞
7.3
7
*
SPAT1164
SPAT
Haemodialysis
+∞
7.3
7
*
9968A
ICD-9 Finland
Complications peculiar to certain specified procedures, Complications of transplanted organ
+∞
7.3
7
*
5821A
ICD-9 Finland
Chronic glomerulonephritis, With lesion of membranous glomerulonephritis[GLOMERULONEPHRITIS CHRONICA MEMBRANACEA,EI NEFR SDR]
+∞
7.3
7
*
N00
ICD-10 Finland
Acute nephritic syndrome
+∞
7.3
7
*
TKA02
NOMESCO Finland
Needle biopsy of transplanted kidney
+∞
7.3
7
*
TK822
NOMESCO Finland
Assessment of adequacy of peritoneal dialysis
+∞
7.3
7
*
N083, E112
ICD-10 Finland
NA
+∞
7.3
7
*
B04AB02
ATC
NA
3.9
7.3
28
73
N12
ICD-10 Finland
Tubulo-interstitial nephritis, not specified as acute or chronic
4.3
7.2
25
59
C02DE10
ATC
NA
5.5
7.2
20
37
A28
ICPC
Limited function/disability NOS
1.8
7.2
132
786
A10AD01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)
4.1
7.2
26
64
EBA10
NOMESCO Finland
Surgical removal of tooth
1.8
7.2
118
681
783
NOMESCO Finland
NA
30.2
7.2
9
*
H3603, E107
ICD-10 Finland
NA
30.2
7.2
9
*
N13.9
ICD-10 Finland
Obstructive and reflux uropathy, unspecified
20.2
7.1
10
5
L03.1
ICD-10 Finland
Cellulitis of other parts of limb
3.5
7.1
31
90
O99.89
ICD-10 Finland
Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
5.3
7.1
20
38
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
3.8
7.1
28
75
5901A
ICD-9 Finland
Infections of kidney, Acute pyelonephritis
6.1
7.1
18
30
H3603, E113
ICD-10 Finland
NA
6.1
7.1
18
30
G63.2*E10.4
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic polyneuropathy
12.1
7.1
12
10
ZY010
NOMESCO Finland
Hospital outpatient
2.3
7.1
62
278
K05.30
ICD-10 Finland
Periodontitis complex
1.9
7.1
105
586
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
10.1
7.0
13
13
IEP02
NOMESCO Finland
Child-centred family therapy
5.2
7.0
20
39
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
4.3
6.9
24
57
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
5.9
6.9
18
31
WX722
NOMESCO Finland
PEEP
2.4
6.9
57
246
CKC12
NOMESCO Finland
Photocoagulation of retina
2.6
6.9
46
180
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
2.2
6.8
65
302
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.6
6.8
172
1126
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
3.7
6.8
28
78
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
3.1
6.8
35
116
PD4CG
NOMESCO Finland
Extensive MRI examination of abdominal aortta and vasculature of lower extremities with high intensity magnet
5.4
6.8
19
36
59199
ICD-8 Finland
Hydronephrosis
40.3
6.8
8
*
N08.30
ICD-10 Finland
Glomerular disorders in diabetes mellitus microalbuminuria
40.3
6.8
8
*
A08.1
ICD-10 Finland
Acute gastroenteropathy due to Norovirus
16.8
6.7
10
6
TQW80
NOMESCO Finland
Local dermatologic skincare
3.2
6.7
33
106
N11.8
ICD-10 Finland
Other chronic tubulo-interstitial nephritis
22.7
6.7
9
*
ZX197
NOMESCO Finland
NA
22.7
6.7
9
*
J01CF05
ATC
flucloxacillin; systemic
2.7
6.7
43
163
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
2.3
6.7
57
254
J01FA06
ATC
roxithromycin; oral
1.4
6.6
349
2692
K03.29
ICD-10 Finland
Erosion of teeth occupational
6.5
6.6
16
25
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
5.2
6.6
19
37
B99
ICD-10 Finland
Other and unspecified infectious diseases
3.8
6.6
26
70
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.0
6.6
77
391
9732/3-C42.1
ICD-O-3
Plasma cell myeloma of bone marrow
12.3
6.6
11
9
D04.6
ICD-10 Finland
Carcinoma in situ: Skin of upper limb, including shoulder
8.8
6.6
13
15
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.0
6.5
83
436
X59
ICD-10 Finland
Exposure to unspecified factor
1.6
6.5
174
1156
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
6.9
6.5
15
22
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.7
6.5
126
767
ZXD20
NOMESCO Finland
Day surgery
1.7
6.5
121
728
7100A
ICD-9 Finland
Diffuse diseases of connective tissue, Systemic lupus erythematosus
70.3
6.4
7
*
L04AA10
ATC
sirolimus; oral
70.3
6.4
7
*
Q87.80
ICD-10 Finland
Alport syndrome
70.3
6.4
7
*
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.1
6.4
70
348
C09AA01
ATC
captopril; oral
3.6
6.4
27
77
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
2.2
6.4
62
290
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.1
6.4
69
339
PF1BT
NOMESCO Finland
Extensive PTA of arteries of knee, lower leg and ankle
8.2
6.3
13
16
X57
ICD-10 Finland
Unspecified privation
3.2
6.3
31
100
RJ421
NOMESCO Finland
NA
9.3
6.3
12
13
N30.0
ICD-10 Finland
Acute cystitis
1.8
6.3
109
642
M32.0
ICD-10 Finland
Drug-induced systemic lupus erythematosus
18.1
6.3
9
5
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.6
6.3
155
1011
5822B
ICD-9 Finland
Chronic glomerulonephritis, With lesion of membranoproliferative glomerulonephritis[GLOMERULONEPHRITIS CHRONICA MESANGIOCAP,NEFR SDR]
+∞
6.3
6
*
N04.7
ICD-10 Finland
Nephrotic syndrome, diffuse crescentic glomerulonephritis
+∞
6.3
6
*
N08.32
ICD-10 Finland
Glomerular disorders in diabetes mellitus kidney failure
+∞
6.3
6
*
N08.3
ICD-10 Finland
Glomerular disorders in diabetes mellitus
+∞
6.3
6
*
OAB70
NOMESCO Finland
Guidance related to hydration
+∞
6.3
6
*
N08.2*D89.82
ICD-10 Finland
Nepropathy caused by deposition of the light chain of the immunoglobulins
+∞
6.3
6
*
N05.2
ICD-10 Finland
Unspecified nephritic syndrome, diffuse membranous glomerulonephritis
+∞
6.3
6
*
E42
ICD-10 Finland
Marasmic kwashiorkor
+∞
6.3
6
*
5809B
ICD-9 Finland
Acute glomerulonephritis with unspecified pathological lesion in kidney[GLOMERULONEPHRITIS ACUTA NUD,NEFR SDR]
+∞
6.3
6
*
I51.1
ICD-10 Finland
Rupture of chordae tendineae, not elsewhere classified
+∞
6.3
6
*
N00.8
ICD-10 Finland
Acute nephritic syndrome, Other
+∞
6.3
6
*
H3600, E113
ICD-10 Finland
NA
4.8
6.2
19
40
D638, N189
ICD-10 Finland
NA
26.8
6.2
8
*
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
2.9
6.2
36
128
46100
ICD-8 Finland
Acute sinusitis, Maxillaris
3.2
6.2
30
96
J01DA01
ATC
[U] cefalexin; systemic
1.4
6.2
572
4868
WX140
NOMESCO Finland
Parabulbar anesthesy
2.4
6.2
47
197
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
4.7
6.1
19
41
TNX34
NOMESCO Finland
Major custom molded cast, unspecified region
4.1
6.1
22
55
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.8
6.1
112
668
D04.7
ICD-10 Finland
Carcinoma in situ: Skin of lower limb, including hip
12.6
6.1
10
8
NDQ20
NOMESCO Finland
Amputation of finger
8.7
6.1
12
14
SBB20
NOMESCO Finland
Tooth X-ray examination in conjunction with visit to dentist
4.9
6.1
18
37
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.2
6.1
58
273
TPW99
NOMESCO Finland
Other minor surgical procedure on peripheral vessel or lymphatic system
4.4
6.1
20
46
S76
ICPC
Skin infection other
2.4
6.0
49
211
2500A
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE,TYYPPI II]
4.0
6.0
22
56
Mortality – FinRegistry
↥Association
Association between endpoint N14_NEPHROTICSYND and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| N14_NEPHROTICSYND | 3.48 [2.92, 4.15] | < 0.001 |
| Birth year | 0.99 [0.98, 1.0] | 0.035 |
During the follow-up period (1.1.1998 — 31.12.2019), 568 out of 2059 females with N14_NEPHROTICSYND died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| N14_NEPHROTICSYND | 3.206 [2.77, 3.72] | < 0.001 |
| Birth year | 0.99 [0.98, 1.0] | 0.029 |
During the follow-up period (1.1.1998 — 31.12.2019), 976 out of 2797 males with N14_NEPHROTICSYND died.
Mortality risk
Mortality risk for people of age
years, who have N14_NEPHROTICSYND.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.276% | 0.78% |
| 5 | 1.842% | 4.366% |
| 10 | 4.395% | 10.506% |
| 15 | 8.503% | 18.736% |
| 20 | 13.598% | 30.558% |
Relationships between endpoints
↥Index endpoint: N14_NEPHROTICSYND – Nephrotic syndrome
GWS hits: 3
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data