myositis: An inflammatory disease involving a pathogenic inflammatory response in the muscle tissue.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
968 |
4. Check minimum number of eventsNone |
968 |
5. Include endpointsNone |
968 |
6. Filter based on genotype QC (FinnGen only) |
968 |
Control definitions (FinnGen only)
- Control exclude
- M13_SOFTTISSUE
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- M60-M63
- Name in latin
- Myositis
Similar endpoints
↥List of similar endpoints to
Myositis
based on the number of shared cases.
Similar with more cases:
- Disorders of muscles
- Soft tissue disorders
- Diseases of the musculoskeletal system and connective tissue
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 7204 | 3423 | 3738 |
| Only index persons | 6302 | 3063 | 3239 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.10 | 0.10 | 0.10 |
| Only index persons | 0.12 | 0.11 | 0.12 |
| Median age at first event (years) | |||
| Whole population | 49.20 | 52.96 | 45.69 |
| Only index persons | 48.87 | 52.23 | 45.69 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 968 | 497 | 471 |
| Unadjusted period prevalence (%) | 0.19 | 0.17 | 0.21 |
| Median age at first event (years) | 55.84 | 52.78 | 59.07 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 876
- Matched controls
- 8760
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M60.9
ICD-10 Finland
Myositis, unspecified
7043.9
323.0
506
*
M60.8
ICD-10 Finland
Other myositis
+∞
222.6
204
*
M60.0
ICD-10 Finland
Infective myositis
+∞
119.6
112
*
M33.2
ICD-10 Finland
Polymyositis
579.4
106.1
103
*
NXL00
NOMESCO Finland
Biopsy of muscle
+∞
102.1
96
*
G72.9
ICD-10 Finland
Myopathy, unspecified
78.4
92.7
104
15
73299
ICD-8 Finland
Infective myositis and other inflammatory diseases of tendon and fascia
+∞
69.7
66
*
H02AB06
ATC
prednisolone; systemic
3.6
69.2
522
2555
NJ3BG
NOMESCO Finland
MRI examination of extremities with high intensity magnet
181.0
64.9
67
*
NJ3CG
NOMESCO Finland
Extensive MRI examination of extremities with median high magnet
105.1
62.8
68
7
M79.6
ICD-10 Finland
Pain in limb
3.6
55.4
326
1250
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
5.2
54.6
188
436
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
5.9
54.3
166
334
L04AX01
ATC
azathioprine; systemic
8.8
48.8
109
139
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.9
44.4
362
1692
M79.1
ICD-10 Finland
Myalgia
5.1
43.2
148
335
A02BC02
ATC
pantoprazole; systemic
2.7
41.7
614
4038
M33.9
ICD-10 Finland
Dermatopolymyositis, unspecified
415.6
40.4
40
*
N03AX16
ATC
pregabalin; oral
3.3
40.4
243
909
N03AX12
ATC
gabapentin; oral
4.1
38.7
169
485
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
6.1
36.8
105
190
N02AX02
ATC
tramadol; systemic, rectal
2.6
35.3
380
2022
M60.2
ICD-10 Finland
Foreign body granuloma of soft tissue, not elsewhere classified
360.9
35.2
35
*
L28
ICPC
Limited function/disability (L)
3.5
33.7
182
618
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.4
33.4
425
2448
M60.1
ICD-10 Finland
Interstitial myositis
+∞
32.5
31
*
G72.8
ICD-10 Finland
Other specified myopathies
13.9
31.8
55
42
M75.1
ICD-10 Finland
Rotator cuff syndrome
3.3
31.4
176
612
M79.0
ICD-10 Finland
Rheumatism, unspecified
44.0
31.1
38
9
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
3.1
29.8
187
704
R4110
NOMESCO Finland
Physiotherapy
2.5
27.7
263
1268
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.5
27.5
282
1416
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
4.4
27.1
104
260
M25.5
ICD-10 Finland
Pain in joint
2.6
26.7
244
1147
P01BA02
ATC
hydroxychloroquine; oral
4.3
26.7
105
269
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.4
25.4
271
1377
NGA20
NOMESCO Finland
Exploration of soft tissue knee or lower leg, open
51.6
25.4
30
6
G71.9
ICD-10 Finland
Primary disorder of muscle, unspecified
+∞
25.1
24
*
H02AB07
ATC
prednisone; oral
3.0
25.0
164
628
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.4
24.7
128
415
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
15.5
24.4
40
27
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.2
23.4
304
1689
N06AX21
ATC
duloxetine; oral
3.8
23.3
104
298
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
4.6
23.1
83
194
M33.1
ICD-10 Finland
Other dermatomyositis
+∞
23.0
22
*
A02BC01
ATC
omeprazole; systemic
2.3
22.3
258
1353
R13
ICD-10 Finland
Dysphagia
4.3
22.2
86
217
C03CA01
ATC
furosemide; systemic
2.3
22.1
259
1363
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
3.8
22.1
99
285
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.2
22.0
269
1443
M03BX02
ATC
tizanidine; oral
2.0
21.4
510
3598
R4120
NOMESCO Finland
Occupational therapy
4.4
21.4
80
195
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
10.7
21.3
41
40
SPAT1229
SPAT
Assessment of need for aid
3.7
21.1
96
279
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
8.7
20.9
45
54
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
3.7
20.8
94
272
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.4
20.7
208
1010
J01FF01
ATC
clindamycin; systemic
2.2
20.4
248
1320
G72.4
ICD-10 Finland
Inflammatory myopathy, not elsewhere classified
+∞
19.9
19
*
JC2KB
NOMESCO Finland
Functional X-ray examination of swallowing
15.8
19.9
32
21
NJ3DG
NOMESCO Finland
Very extensive MRI examination of extremities with high intensity magnet
75.2
19.8
22
*
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
10.1
19.3
38
39
Z3226
NOMESCO Finland
Physiotherapist
2.5
19.0
169
768
N02AJ06
ATC
codeine and paracetamol; systemic
2.0
18.9
307
1841
A02BC05
ATC
esomeprazole; systemic
2.0
18.6
341
2139
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
7.7
18.6
43
58
M01AH05
ATC
etoricoxib; oral
1.9
18.2
465
3283
L19
ICPC
Muscle symptom/complaint NOS
7.2
18.1
44
64
N99
ICPC
Neurological disease other
12.2
17.9
32
27
Z50.1
ICD-10 Finland
Other physical therapy
4.5
17.9
65
154
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
6.8
17.9
45
69
7280A
ICD-9 Finland
Disorders of muscle, ligament and fascia, Infective myositis
+∞
17.8
17
*
M05BA04
ATC
alendronic acid; oral
3.1
17.7
102
355
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.9
17.4
370
2433
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
3.2
17.3
96
323
M01AE02
ATC
naproxen; oral, rectal
1.9
17.2
463
3302
R50.9
ICD-10 Finland
Fever, unspecified
2.6
17.1
140
606
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.7
17.0
77
223
M02AA07
ATC
piroxicam; topical
2.0
17.0
302
1855
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
10.7
16.8
32
31
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.6
16.8
135
579
L04AA06
ATC
mycophenolic acid; systemic
8.2
16.7
37
47
M62.9
ICD-10 Finland
Disorder of muscle, unspecified
91.8
16.6
18
*
G71.08
ICD-10 Finland
Other muscular dystrophy
91.8
16.6
18
*
TPH04
NOMESCO Finland
Cathetrisation of vein
2.2
16.4
190
977
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
6.3
16.2
43
71
M54.9
ICD-10 Finland
Dorsalgia, unspecified
3.0
16.2
99
359
S18
ICPC
Laceration/cut
1.9
16.1
355
2348
R07.4
ICD-10 Finland
Chest pain, unspecified
2.1
16.1
228
1278
N02BE01
ATC
paracetamol; systemic, rectal
2.0
16.1
716
6018
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.7
15.7
110
435
M54.4
ICD-10 Finland
Lumbago with sciatica
2.5
15.6
134
594
AA1AD
NOMESCO Finland
CT of head and brain
2.1
15.6
212
1167
R60.0
ICD-10 Finland
Localized oedema
2.7
15.5
110
438
R53
ICD-10 Finland
Malaise and fatigue
2.2
15.4
177
902
X59
ICD-10 Finland
Exposure to unspecified factor
2.3
15.4
156
752
R51.80
ICD-10 Finland
Headache
2.6
15.4
121
511
C07AB07
ATC
bisoprolol; oral
1.8
15.3
387
2665
R52.2
ICD-10 Finland
Other chronic pain
8.0
15.2
34
44
R1250
NOMESCO Finland
Evaluation of functional capability
7.3
15.2
36
51
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
4.0
15.2
62
165
M48.0
ICD-10 Finland
Spinal stenosis
2.7
15.0
107
428
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
3.7
15.0
67
193
N03AE01
ATC
clonazepam; systemic
3.9
14.8
61
164
L99
ICPC
Musculoskeletal disease other
7.1
14.5
35
51
R06.0
ICD-10 Finland
Dyspnoea
2.0
14.5
208
1167
M19.0
ICD-10 Finland
Primary arthrosis of other joints
3.3
14.3
74
239
J01FA06
ATC
roxithromycin; oral
1.8
14.3
335
2235
M72.0
ICD-10 Finland
Palmar fascial fibromatosis [Dupuytren]
19.5
14.3
21
11
M13.9
ICD-10 Finland
Arthritis, unspecified
3.4
14.2
69
212
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
4.0
14.1
57
150
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
3.1
14.1
79
268
C10AX09
ATC
ezetimibe; oral
2.6
14.0
104
424
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
3.9
14.0
58
156
SPAT1231
SPAT
Assessment of adjustments needed in living environment
6.7
14.0
35
54
J01DB01
ATC
cefalexin; oral
1.9
13.9
680
5696
SPAT1216
SPAT
Assessment of functional ability
2.3
13.8
139
666
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
4.8
13.7
45
97
N06AA09
ATC
amitriptyline; systemic
2.9
13.6
86
318
Z01.8
ICD-10 Finland
Other specified special examinations
2.1
13.5
176
944
A02BC03
ATC
lansoprazole; oral
1.9
13.5
232
1384
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.5
13.3
113
496
N02AA05
ATC
oxycodone; systemic
2.3
13.2
128
599
A28
ICPC
Limited function/disability NOS
2.3
13.2
135
651
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.1
13.1
156
805
A02BA02
ATC
ranitidine; systemic
2.1
13.1
163
858
M01AE03
ATC
ketoprofen; systemic, rectal
1.8
13.1
301
1985
XF400
NOMESCO Finland
ECG with 12 standard connections
2.2
13.0
147
741
M54.5
ICD-10 Finland
Low back pain
1.9
13.0
245
1508
M70.6
ICD-10 Finland
Trochanteric bursitis
2.7
13.0
91
358
M47.82
ICD-10 Finland
Other spondylosis, cervical region
4.7
13.0
44
98
M01AC06
ATC
meloxicam; systemic, rectal
1.8
13.0
288
1876
R26.8
ICD-10 Finland
Other and unspecified abnormalities of gait and mobility
6.7
12.9
32
49
SPAT1153
SPAT
Removal of sutures
1.8
12.7
262
1664
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.9
12.6
199
1150
G56.0
ICD-10 Finland
Carpal tunnel syndrome
2.6
12.5
97
404
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.3
12.4
125
595
M01AX17
ATC
nimesulide; oral
1.9
12.4
194
1115
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
4.7
12.3
41
90
M60
ICD-10 Finland
Myositis
38.1
12.2
15
*
R60.9
ICD-10 Finland
Oedema, unspecified
3.9
12.2
50
134
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
6.0
12.2
33
57
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.8
12.1
80
305
M35.1
ICD-10 Finland
Other overlap syndromes
18.3
12.1
18
10
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
4.0
12.0
48
126
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.4
12.0
59
184
NDM10
NOMESCO Finland
Palmar fasciotomy of hand
47.3
11.9
14
*
M03BC01
ATC
orphenadrine (citrate); systemic
2.0
11.9
173
968
R03AC02
ATC
salbutamol; inhalant
1.7
11.8
400
2936
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.7
11.8
80
309
J02AC01
ATC
fluconazole; systemic
1.7
11.8
297
2001
XA402
NOMESCO Finland
ENMG
6.4
11.8
30
48
NE1AA
NOMESCO Finland
Pelvis X-ray examination
3.2
11.7
62
204
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.1
11.7
138
708
M17.1
ICD-10 Finland
Other primary gonarthrosis
2.0
11.7
161
880
L17
ICPC
Foot/toe symptom/complaint
1.9
11.7
199
1179
ZXE00
NOMESCO Finland
One hour or less
1.7
11.6
323
2235
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.1
11.6
143
744
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.1
11.6
143
745
J45.9
ICD-10 Finland
Asthma, unspecified
2.1
11.6
135
688
J01DA01
ATC
[U] cefalexin; systemic
1.6
11.6
497
3880
M01AH01
ATC
celecoxib; oral (coxibs)
2.1
11.6
141
734
SAA03
NOMESCO Finland
Extended examination of mouth
1.7
11.5
308
2107
NBG10
NOMESCO Finland
Acromioplastia
13.8
11.5
19
14
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
13.8
11.5
19
14
J99.1*M33.2
ICD-10 Finland
Respiratory disorders in polymyositis
+∞
11.5
11
*
M79.7
ICD-10 Finland
Fibromyalgia
9.0
11.3
23
26
M01AB05
ATC
diclofenac; systemic, rectal
1.6
11.3
520
4128
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.4
11.2
96
423
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.1
11.2
128
646
WX110
NOMESCO Finland
Local anesthesy
1.6
11.1
554
4481
M35.3
ICD-10 Finland
Polymyalgia rheumatica
3.8
11.0
46
126
B01AB05
ATC
enoxaparin; parenteral
1.8
11.0
240
1538
M47.9
ICD-10 Finland
Spondylosis, unspecified
5.4
11.0
32
61
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.0
10.9
146
786
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.9
10.9
188
1115
C08CA05
ATC
nifedipine; systemic
3.0
10.9
62
214
NDM40
NOMESCO Finland
Discission of sheath of tendon of wrist or hand
28.4
10.7
14
5
M01AH02
ATC
rofecoxib; oral
2.3
10.7
101
468
L04AA13
ATC
leflunomide; oral
5.1
10.7
33
67
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
10.7
294
2017
M03BC51
ATC
orphenadrine, combinations; systemic
1.8
10.7
214
1331
Z3231
NOMESCO Finland
Registered nurse
1.8
10.7
223
1406
A46
ICD-10 Finland
Erysipelas
2.2
10.7
114
559
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
5.6
10.6
30
55
L29
ICPC
Musculoskeletal sympt/complt other
2.8
10.6
69
260
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.1
10.5
124
636
SPAT1215
SPAT
Assessment of need for medical rehabilitation
3.5
10.5
48
142
G47.3
ICD-10 Finland
Sleep apnoea
1.9
10.5
173
1011
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
3.2
10.5
55
181
J01MA02
ATC
ciprofloxacin; systemic
1.7
10.5
302
2097
A06AD11
ATC
lactulose; oral
2.2
10.4
115
573
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.0
10.3
149
829
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
2.6
10.3
76
311
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
2.4
10.2
89
397
SPAT1249
SPAT
Treatment-related counselling outside office
1.6
10.1
314
2225
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.9
10.0
169
990
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
3.7
10.0
43
121
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.3
10.0
91
414
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.7
10.0
250
1666
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.0
9.9
129
689
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.7
9.8
226
1468
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.7
9.8
65
248
N28
ICPC
Limited function/disability (N)
6.2
9.7
25
41
ZXD05
NOMESCO Finland
Urgent procedure
1.7
9.7
247
1649
S46.0
ICD-10 Finland
Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder
2.9
9.7
60
220
WX203
NOMESCO Finland
Infraclavicular plexus blockade
6.5
9.6
24
38
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
5.2
9.4
28
55
NDM20
NOMESCO Finland
Excision of synovial ganglion of wrist or hand
101.0
9.4
10
*
NBT60
NOMESCO Finland
Forcible manipulation of humeroscapular joint
101.0
9.4
10
*
TNX05
NOMESCO Finland
Simple incision of soft tissue, unspecified region
101.0
9.4
10
*
H04.10
ICD-10 Finland
Dry eye syndrome
2.4
9.4
79
345
N18
ICPC
Paralysis/weakness
6.3
9.4
24
39
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.6
9.4
311
2227
R42
ICD-10 Finland
Dizziness and giddiness
1.8
9.4
164
973
N06AX11
ATC
mirtazapine; oral
1.7
9.4
240
1603
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
8.2
9.4
20
25
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.5
9.4
73
307
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.6
9.3
66
263
M65.3
ICD-10 Finland
Trigger finger
6.5
9.3
23
36
UJF32
NOMESCO Finland
Coloscopy
1.7
9.2
203
1298
ZX120
NOMESCO Finland
Intravenous
2.3
9.2
88
410
M01AE01
ATC
ibuprofen; systemic, rectal
1.7
9.2
732
6516
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
2.7
9.1
62
242
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
2.2
9.1
92
441
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
2.1
9.1
99
491
R06AE07
ATC
cetirizine; oral
1.6
9.0
322
2346
WX892
NOMESCO Finland
Monitored bed care
2.5
9.0
70
293
D07AC01
ATC
betamethasone; topical
1.6
9.0
270
1883
WX002
NOMESCO Finland
Sedation and analgesia
1.8
9.0
157
931
L88
ICPC
Rheumatoid/seropositive arthritis
3.3
8.9
44
139
R5599
NOMESCO Finland
Other rehabilitation service
4.4
8.9
31
73
ZXD10
NOMESCO Finland
Scheduled procedure
1.6
8.9
298
2135
J01MA12
ATC
levofloxacin; systemic
1.9
8.9
148
864
TAB00
NOMESCO Finland
Lumbar puncture
3.3
8.9
44
140
Z71.8
ICD-10 Finland
Other specified counselling
1.8
8.9
180
1119
M01AX01
ATC
nabumetone; oral
3.4
8.8
41
124
C03DA01
ATC
spironolactone; oral
2.2
8.8
90
432
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
8.8
212
1387
Z00.0
ICD-10 Finland
General medical examination
1.9
8.8
144
835
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.4
8.8
77
342
K22.4
ICD-10 Finland
Dyskinesia of oesophagus
14.2
8.7
14
10
S06.0
ICD-10 Finland
Concussion
2.2
8.7
87
415
R07.3
ICD-10 Finland
Other chest pain
2.4
8.7
75
334
Z3229
NOMESCO Finland
Other healthcare associate professional
2.4
8.7
75
334
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.6
8.6
312
2275
L12
ICPC
Hand/finger symptom/complaint
2.1
8.6
98
495
L86
ICPC
Back syndrome with radiating pain
3.0
8.6
49
170
SPAT1301
SPAT
No procedures
1.6
8.6
250
1725
NBA30
NOMESCO Finland
Exploration of joint of shoulder or upper arm, arthroscopic
9.1
8.6
17
19
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.2
8.5
44
144
M53.1
ICD-10 Finland
Cervicobrachial syndrome
2.4
8.5
74
330
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
3.8
8.5
35
96
SPAT1255
SPAT
Intravenous administration of medicine
2.6
8.4
58
229
R5140
NOMESCO Finland
Monitoring the use of the aid
2.2
8.4
87
421
S00.8
ICD-10 Finland
Superficial injury of other parts of head
6.3
8.3
21
34
NCL99
NOMESCO Finland
Other operation on muscle or tendon of elbow or forearm
+∞
8.3
8
*
NBL00
NOMESCO Finland
Suture or reinsertation of rotator cuff of shoulder
3.9
8.3
33
88
N05BA01
ATC
diazepam; systemic, rectal
2.0
8.2
103
539
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.4
8.2
71
314
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
3.8
8.2
33
89
XX9XE
NOMESCO Finland
Other ultrasound examination
17.3
8.1
12
7
P01AB01
ATC
metronidazole; oral, rectal
1.6
8.1
290
2102
E0000UV
ATC
NA
1.6
8.1
301
2205
SPAT1260
SPAT
Consultation of another employee
1.8
8.0
146
875
J01FA10
ATC
azithromycin; systemic
1.5
8.0
445
3561
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.6
8.0
58
235
SAA01
NOMESCO Finland
Simple examination of mouth
1.5
8.0
541
4523
ZXA00
NOMESCO Finland
Right side
1.7
8.0
199
1313
N05CF01
ATC
zopiclone; oral
1.6
8.0
239
1657
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.5
8.0
364
2790
L03
ICPC
Low back symptom/complaint
1.7
7.9
175
1112
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.9
7.9
116
646
NB1CG
NOMESCO Finland
Shoulder and humerus extensive MRI examination with high intensity magnet
6.7
7.9
19
29
Z01.2
ICD-10 Finland
Dental examination
1.5
7.9
303
2230
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
7.9
7.9
17
22
Z2446
NOMESCO Finland
Social worker
2.5
7.9
60
249
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
3.1
7.8
42
142
TQW40
NOMESCO Finland
Remowal of suture of skin
2.5
7.8
60
250
N04BC05
ATC
pramipexole; oral
2.5
7.8
58
239
JCA55
NOMESCO Finland
Endoscopic dilatation of oesophagus
7.0
7.8
18
26
M05BA07
ATC
risedronic acid; oral
3.5
7.8
35
104
M77.4
ICD-10 Finland
Metatarsalgia
3.3
7.8
37
115
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.1
7.7
89
450
ZXA05
NOMESCO Finland
Left side
1.7
7.7
189
1237
M67.4
ICD-10 Finland
Ganglion
3.8
7.7
31
84
N06AX16
ATC
venlafaxine; oral
2.0
7.7
99
524
L13
ICPC
Hip symptom/complaint
1.9
7.6
110
607
M75.0
ICD-10 Finland
Adhesive capsulitis of shoulder
4.3
7.6
27
65
R4130
NOMESCO Finland
Speech therapy
4.3
7.6
27
65
UDQ42
NOMESCO Finland
Endoscopic assessment of swallowing function
18.5
7.6
11
6
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.9
7.6
45
163
H02.3
ICD-10 Finland
Blepharochalasis
2.6
7.6
53
212
XG410
NOMESCO Finland
Flow-volume spirometry
3.1
7.5
39
129
UJC01
NOMESCO Finland
Scopy of lower throat
7.2
7.5
17
24
S93.4
ICD-10 Finland
Sprain and strain of ankle
2.2
7.5
74
352
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
2.4
7.5
62
272
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.7
7.4
166
1061
H57.1
ICD-10 Finland
Ocular pain
3.7
7.4
30
82
M76.9
ICD-10 Finland
Enthesopathy of lower limb, unspecified
13.5
7.4
12
9
N05CF02
ATC
zolpidem; oral
1.8
7.4
134
801
M16.0
ICD-10 Finland
Primary coxarthrosis, bilateral
2.5
7.4
57
239
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.2
7.3
73
348
M01AH03
ATC
valdecoxib; oral
2.6
7.3
51
203
Z08
ICPC
Social welfare problem
6.9
7.3
17
25
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.7
7.3
162
1033
NJ3CM
NOMESCO Finland
Extensive MRI examination of extremities with 3 Tesla magnet
+∞
7.3
7
*
WX290
NOMESCO Finland
Other blockade of nerve
1.5
7.2
321
2428
Z2221
NOMESCO Finland
Medical doctor
1.6
7.2
207
1410
R03DC03
ATC
montelukast; oral
1.9
7.2
112
635
R52.0
ICD-10 Finland
Acute pain
4.0
7.2
27
69
A06AC01
ATC
ispaghula (psylla seeds); oral
1.7
7.2
174
1134
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
2.7
7.2
49
191
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.1
7.1
76
371
M66.0
ICD-10 Finland
Rupture of popliteal cyst
20.2
7.1
10
5
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.5
7.1
398
3162
M47.80
ICD-10 Finland
Other spondylosis, multiple sites in spine
4.4
7.1
24
56
R4190
NOMESCO Finland
Nutritional therapy
3.5
7.1
31
91
M77.1
ICD-10 Finland
Lateral epicondylitis
3.0
7.0
38
130
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
3.4
7.0
32
97
J01FA09
ATC
clarithromycin; systemic
1.6
7.0
225
1581
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.5
7.0
413
3314
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.9
7.0
101
558
SPAT1262
SPAT
Handing over of treatment supplies
1.7
7.0
142
883
A02BC04
ATC
rabeprazole; oral
2.3
7.0
61
275
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.4
6.9
58
255
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
4.7
6.9
22
48
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.5
6.9
291
2173
L14
ICPC
Leg/thigh symptom/complaint
2.4
6.9
58
256
NA3DG
NOMESCO Finland
Lumbar spine very extensive MRI examination with high intensity magnet
13.9
6.9
11
8
G44.2
ICD-10 Finland
Tension-type headache
2.0
6.9
87
458
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
4.9
6.9
21
44
TNX32
NOMESCO Finland
Custom moulded splint, unspecified region
2.8
6.9
42
156
N05BE01
ATC
buspirone; oral
4.2
6.8
24
58
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
2.9
6.8
40
144
C01DA14
ATC
isosorbide mononitrate; oral
1.8
6.8
111
643
QCB10
NOMESCO Finland
Major dressing of wound of skin of upper limb
4.6
6.8
22
49
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.0
6.8
84
438
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
4.3
6.8
23
54
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.5
6.8
50
204
XF402
NOMESCO Finland
ECG with work load test
2.0
6.7
86
457
M54.6
ICD-10 Finland
Pain in thoracic spine
2.6
6.7
45
177
SPAT1212
SPAT
Extensive examination of musculoskeletal system
2.3
6.7
61
278
M46.3
ICD-10 Finland
Infection of intervertebral disc (pyogenic)
22.7
6.7
9
*
M02AA10
ATC
ketoprofen; topical
1.8
6.7
115
678
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.2
6.7
62
288
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.8
6.7
111
645
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.7
6.6
151
965
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
1.9
6.6
95
526
KMAK
NOMESCO Finland
NA
1.5
6.6
385
3072
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.1
6.5
74
372
M54.2
ICD-10 Finland
Cervicalgia
2.4
6.5
52
222
S97
ICPC
Chronic ulcer skin
2.5
6.5
50
211
XF600
NOMESCO Finland
Bloodpressure measurement
2.5
6.5
49
203
M02AA15
ATC
diclofenac; topical (antiinflammatory prep., non-steroids for topical use)
2.3
6.5
60
275
SPAT1263
SPAT
Sampling
1.5
6.5
324
2498
R01AD08
ATC
fluticasone; nasal
1.6
6.5
201
1397
SPAT1296
SPAT
Other function in accordance with occupational therapy nomenclature
6.2
6.5
16
26
N05AH04
ATC
quetiapine; oral
1.8
6.5
118
707
D64.9
ICD-10 Finland
Anaemia, unspecified
2.0
6.5
80
419
M01AG02
ATC
tolfenamic acid; oral, rectal
1.8
6.5
108
631
N06AB10
ATC
escitalopram; oral
1.7
6.5
137
859
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
4.3
6.4
22
52
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.3
6.4
58
266
JCA98
NOMESCO Finland
Other local endoscopic operation on oesophagus
70.3
6.4
7
*
G60.8
ICD-10 Finland
Other hereditary and idiopathic neuropathies
70.3
6.4
7
*
M62.5
ICD-10 Finland
Muscle wasting and atrophy, not elsewhere classified
70.3
6.4
7
*
M33.0
ICD-10 Finland
Juvenile dermatomyositis
70.3
6.4
7
*
TAC00
NOMESCO Finland
Peripheral nerve block
70.3
6.4
7
*
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.4
6.4
422
3437
TAW99
NOMESCO Finland
Other minor neurosurgical procedure
14.4
6.4
10
7
NK1XE
NOMESCO Finland
Other ultrasound examinnation of muscle or tendon
14.4
6.4
10
7
A03FA02
ATC
cisapride; oral, rectal
2.3
6.4
59
271
R1260
NOMESCO Finland
Evaluation of communicative skills
5.0
6.4
19
39
W00
ICD-10 Finland
Fall on same level involving ice and snow
2.0
6.4
83
442
J05AB01
ATC
aciclovir; systemic
1.6
6.4
156
1022
M54.1
ICD-10 Finland
Radiculopathy
3.5
6.3
27
78
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
2.0
6.3
81
430
J01AA02
ATC
doxycycline; systemic
1.5
6.3
603
5272
M04AA01
ATC
allopurinol; systemic
1.9
6.3
92
511
R03BA05
ATC
fluticasone; inhalant
1.7
6.3
126
775
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
2.2
6.3
59
276
G60.9
ICD-10 Finland
Hereditary and idiopathic neuropathy, unspecified
+∞
6.3
6
*
G71.3
ICD-10 Finland
Mitochondrial myopathy, not elsewhere classified
+∞
6.3
6
*
M67.0
ICD-10 Finland
Short Achilles tendon (acquired)
+∞
6.3
6
*
L08
ICPC
Shoulder symptom/complaint
1.7
6.2
121
739
9476
FHL
Splitting of fascia or aponeurosis
26.9
6.2
8
*
R41.0
ICD-10 Finland
Disorientation, unspecified
3.3
6.2
29
90
Y84
ICD-10 Finland
Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
7.1
6.2
14
20
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
2.5
6.2
47
196
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
2.8
6.2
38
142
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.2
6.2
30
96
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
4.3
6.1
21
50
K22.2
ICD-10 Finland
Oesophageal obstruction
7.7
6.1
13
17
Y94.0
ICD-10 Finland
Accident at home
4.7
6.1
19
41
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.2
6.1
62
297
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.6
6.1
173
1175
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.0
6.1
73
379
H02AB04
ATC
methylprednisolone; systemic
1.8
6.0
101
590
R06AX27
ATC
desloratadine; oral
1.6
6.0
181
1246
N05CD07
ATC
temazepam; oral
1.9
6.0
92
521
R11
ICD-10 Finland
Nausea and vomiting
2.2
6.0
59
279
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
3.1
6.0
31
104
M05BX04
ATC
denosumab; parenteral
2.6
6.0
40
157
Mortality – FinRegistry
↥Association
Association between endpoint M13_MYOSITIS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_MYOSITIS | 1.699 [1.49, 1.94] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.236 |
During the follow-up period (1.1.1998 — 31.12.2019), 503 out of 2586 females with M13_MYOSITIS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_MYOSITIS | 1.774 [1.52, 2.07] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.005 |
During the follow-up period (1.1.1998 — 31.12.2019), 567 out of 2795 males with M13_MYOSITIS died.
Mortality risk
Mortality risk for people of age
years, who have M13_MYOSITIS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.163% | 0.313% |
| 5 | 0.885% | 2.16% |
| 10 | 2.391% | 5.604% |
| 15 | 4.697% | 10.214% |
| 20 | 8.407% | 16.702% |
Relationships between endpoints
↥Index endpoint: M13_MYOSITIS – Myositis
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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