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Interstitial myositis

Endpoint Browser

MYOSINTERST

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — M60.1
  • Cause of death: ICD-10 — M60.1

2 out of 7 registries used, show all original rules.

37

4. Check minimum number of events

None

37

5. Include endpoints

None

37

6. Filter based on genotype QC (FinnGen only)

37

Control definitions (FinnGen only)

Control exclude
ILD_SYST_AUTO_DISEASES

Extra metadata

First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M60
Name in latin
Myositis interstitialis

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 254 185 68
Only index persons 232 171 61
Unadjusted period prevalence (%)
Whole population 0.00 0.01 0.00
Only index persons 0.01 0.01 0.00
Median age at first event (years)
Whole population 54.03 51.11 61.84
Only index persons 52.29 49.06 61.34

-FinnGen-

Key figures

All Female Male
Number of individuals 37 23 14
Unadjusted period prevalence (%) 0.01 0.01 0.01
Median age at first event (years) 54.83 48.59 65.09

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3027953) Aldolase [Enzymatic activity/volume] in Serum or Plasma
5
0
+∞
5.32
4.2
0.0
u/l
7.2
—
—
5
0
(3005895) Myoglobin [Mass/volume] in Serum or Plasma
5
6
9.37
2.83
1.8
1.2
ug/l
113.0
342.5
—
5
6
(3032080) INR in Blood by Coagulation assay
20
105
2.97
2.63
5.8
9.4
inr
1.0
1.2
—
5
30
(42870588) Differential panel, method unspecified - Blood
18
95
2.74
2.27
7.3
4.7
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
12
51
3.00
2.23
1.0
1.4
—
—
—
0
0
(3019198) Lymphocytes [#/volume] in Blood
21
145
2.04
1.24
8.9
5.3
e9/l
2.1
2.2
0.12
21
123
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
19
129
1.97
1.15
1.6
2.0
pmol/l
108.4
94.4
—
10
61
(3001122) Ferritin [Mass/volume] in Serum or Plasma
18
127
1.81
0.92
2.2
2.4
ug/l
62.2
108.5
1.51
18
118
(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma
15
100
1.84
0.92
3.6
2.9
u/l
30.7
26.9
0.76
15
95
(46235355) HIV 1 and 2 tests - Meaningful Use set
8
45
1.99
0.92
1.4
1.2
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
25
196
1.85
0.90
4.6
4.1
—
—
—
0
0
(3017143) Hepatitis C virus Ab [Presence] in Serum
6
31
2.11
0.89
1.0
1.4
—
—
—
0
0
(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma
22
168
1.76
0.84
4.9
7.3
umol/l
10.4
12.2
0.41
22
162
(3022621) pH of Urine by Test strip
5
23
2.35
0.79
3.8
3.2
—
—
—
0
0
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
5
29
1.83
0.66
1.2
1.4
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
0
22
0.00
0.61
0.0
1.1
—
—
—
0
0
(3009261) Glucose [Presence] in Urine by Test strip
18
139
1.57
0.60
3.2
3.6
—
0.0
—
0
25
(3011397) Hemoglobin [Presence] in Urine by Test strip
9
62
1.59
0.59
3.0
3.8
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
6
37
1.74
0.59
1.2
1.3
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
8
116
0.60
0.58
4.1
2.7
—
—
—
0
0
(40758558) Short blood count panel - Blood
12
87
1.56
0.50
8.8
9.0
—
—
—
0
0
(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma
13
98
1.50
0.45
2.5
2.2
u/l
57.2
57.1
0.01
13
87
(21494755) Public health laboratory ask at order entry panel
5
33
1.59
0.43
1.4
1.3
—
—
—
0
0
(3013512) EKG study
12
90
1.49
0.43
4.9
3.5
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
12
90
1.49
0.43
3.4
3.2
—
—
—
0
0
(3016502) Oxygen saturation in Arterial blood
5
35
1.49
0.41
2.0
6.4
%
98.0
95.6
—
5
35
(3003694) ABO and Rh group [Type] in Blood
5
77
0.60
0.41
1.2
1.4
—
—
—
0
0
(3021601) Nitrite [Presence] in Urine by Test strip
17
138
1.43
0.41
5.5
4.9
—
0.0
—
0
28
(3010813) Leukocytes [#/volume] in Blood
32
334
0.69
0.40
28.3
21.4
e9/l
6.5
6.8
0.40
32
324
(3026361) Erythrocytes [#/volume] in Blood
32
334
0.69
0.40
28.2
21.3
e12/l
4.4
4.5
0.56
32
325
(40768804) Tissue Pathology biopsy report
10
128
0.70
0.34
2.5
1.9
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
7
51
1.46
0.34
1.0
1.7
—
—
—
0
0
(3029937) Albumin [Presence] in Urine by Test strip
5
72
0.65
0.29
1.4
4.0
—
0.0
—
0
26
(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma
24
214
1.35
0.29
4.2
2.6
u/l
32.2
40.7
0.61
24
203
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
16
135
1.33
0.28
4.0
3.5
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
12
97
1.35
0.27
2.5
2.0
—
—
—
0
0
(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma
7
89
0.74
0.26
3.9
4.7
ug/l
1.1
2.4
—
7
82
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
5
37
1.40
0.25
1.0
1.7
—
—
—
0
0
(3007461) Platelets [#/volume] in Blood
32
333
0.71
0.25
28.2
21.4
e9/l
268.9
253.6
0.65
32
326
(3035350) Ketones [Presence] in Urine by Test strip
16
137
1.30
0.24
3.3
3.6
—
0.0
—
0
26
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
5
38
1.36
0.24
1.0
1.6
—
—
—
0
0
(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum
0
11
0.00
0.22
0.0
1.0
—
—
—
0
0
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
0
11
0.00
0.22
0.0
2.5
—
—
—
0
0
(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma
0
10
0.00
0.22
0.0
3.7
—
17.6
—
0
10
(3036489) Thrombin time
0
10
0.00
0.22
0.0
3.3
—
20.3
—
0
10
(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain
0
10
0.00
0.22
0.0
1.2
—
—
—
0
0
(3019309) Folate [Moles/volume] in Red Blood Cells
6
48
1.30
0.21
1.8
1.6
nmol/l
861.7
1034.6
—
6
38
(3015736) pH of Urine
12
100
1.30
0.21
3.6
3.3
—
—
—
0
0
(3049717) Cytology report of Urine Cyto stain
0
12
0.00
0.21
0.0
2.7
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
13
110
1.28
0.21
2.6
3.2
—
—
—
0
0
(3023368) Bacteria identified in Blood by Culture
6
76
0.75
0.17
4.3
4.6
—
—
—
0
0
(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma
27
252
1.26
0.17
10.0
7.4
u/l
76.0
77.4
0.11
27
237
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
20
182
1.22
0.16
2.6
2.8
—
—
—
0
0
(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma
5
43
1.19
0.10
2.4
2.8
umol/l
3.8
6.6
—
5
35
(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma
32
326
0.86
0.10
15.6
10.5
u/l
28.2
24.4
1.30
32
320
(40760892) CBC W Ordered Manual Differential panel - Blood
6
55
1.11
0.09
2.5
7.3
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
8
73
1.12
0.08
3.1
2.0
—
—
—
0
0
(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma
8
75
1.08
0.08
1.6
1.8
mg/l
3.9
3.0
—
8
65
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
12
110
1.13
0.06
5.1
3.9
ng/l
33.8
32.5
0.03
12
79
(3044889) 12 lead EKG panel
22
210
1.12
0.05
4.5
3.9
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
10
94
1.09
0.01
2.6
2.9
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
10
101
0.99
0.00
3.1
3.9
—
—
—
0
0
(3031040) Bacteria [#/volume] in Urine by Automated count
20
197
1.03
0.00
3.9
4.4
—
9229.8
—
0
6
(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method
0
8
0.00
0.00
0.0
3.6
—
98.5
—
0
8
(3032035) Polymorphonuclear cells/100 leukocytes in Blood
0
6
0.00
0.00
0.0
2.0
—
50.3
—
0
6
(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3003740) Influenza virus B Ag [Presence] in Specimen
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(40761511) CBC panel - Blood by Automated count
32
316
1.09
0.00
18.7
12.0
—
—
—
0
0
(3020287) Protein C actual/normal in Platelet poor plasma by Coagulation assay
0
5
0.00
0.00
0.0
1.0
—
112.6
—
0
5
(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
30
302
0.97
0.00
6.0
4.5
mmol/l
4.9
4.6
0.86
30
287
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
5
51
0.98
0.00
1.4
1.4
—
—
—
0
0
(3019550) Sodium [Moles/volume] in Serum or Plasma
32
314
1.14
0.00
18.5
16.5
mmol/l
139.6
139.7
0.12
32
308
(3039443) Prostate specific Ag panel - Serum or Plasma
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
(40763082) Lactate dehydrogenase [Enzymatic activity/volume] in Pleural fluid by Lactate to pyruvate reaction
0
5
0.00
0.00
0.0
1.2
—
251.3
—
0
5
(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
2.6
—
—
—
0
0
(3019250) Coagulation factor VIII activity actual/normal in Platelet poor plasma by Coagulation assay
0
8
0.00
0.00
0.0
3.8
—
217.5
—
0
8
(3009445) Proteinase 3 Ab [Units/volume] in Serum
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(1616796) Gas panel - Central venous blood
0
5
0.00
0.00
0.0
2.6
—
—
—
0
0
(3003284) Neutrophil cytoplasmic Ab.perinuclear [Titer] in Serum by Immunofluorescence
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
2.3
—
—
—
0
0
(3028271) Lactate [Moles/volume] in Capillary blood
0
5
0.00
0.00
0.0
3.4
—
1.6
—
0
5
(3014702) Chromogranin A [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.6
—
2.3
—
0
5
(3020564) Creatinine [Moles/volume] in Serum or Plasma
32
321
0.98
0.00
21.4
17.2
umol/l
73.2
77.3
0.42
32
321
(3041096) Erythrocytes [Presence] in Urine by Automated
7
76
0.90
0.00
3.6
3.3
—
—
—
0
0
(3032773) Endomysium IgG Ab [Titer] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(40768800) Prostate Pathology biopsy report
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3040151) Glucose [Moles/volume] in Capillary blood
0
5
0.00
0.00
0.0
39.4
—
7.6
—
0
5
(40758310) Human epididymis protein 4 [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.3
—
90.2
—
0
6
(3023103) Potassium [Moles/volume] in Serum or Plasma
32
315
1.12
0.00
18.2
16.6
mmol/l
4.0
4.0
0.84
32
310
(3018387) Mycoplasma pneumoniae IgG Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3023511) Choriogonadotropin [Units/volume] in Urine
0
8
0.00
0.00
0.0
2.0
—
—
—
0
0
(3045424) Erythrocytes [Presence] in Urine
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(3009340) Metanephrine [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
2.4
—
—
—
0
0
(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3017817) Protein [Mass] in Urine collected for unspecified duration
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3002523) Influenza virus A Ag [Presence] in Specimen
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(40767503) Oxygen content in Capillary blood by calculation
0
6
0.00
0.00
0.0
3.0
—
—
—
0
0
(3009542) Hematocrit [Volume Fraction] of Blood
28
275
1.07
0.00
22.3
15.5
%
40.0
40.2
0.09
21
214
(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(40768806) Pleura Pathology biopsy report
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3016407) Fibrinogen [Mass/volume] in Platelet poor plasma by Coagulation assay
0
5
0.00
0.00
0.0
6.0
—
3.8
—
0
5
(3030905) Polymorphonuclear cells [#/volume] in Blood
0
6
0.00
0.00
0.0
2.0
—
3.5
—
0
6
(3035880) pH of Pleural fluid
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(4268621)
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3010130) Cytomegalovirus IgG Ab [Units/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3045788) Cell count panel - Pleural fluid
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3022806) Fractional oxyhemoglobin in Capillary blood
0
5
0.00
0.00
0.0
3.4
—
88.5
—
0
5
(3020629) Protein S Free Ag actual/normal in Platelet poor plasma by Immunoassay
0
5
0.00
0.00
0.0
1.0
—
96.2
—
0
5
(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(21494890) Protein electrophoresis panel - 24 hour Urine
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
2.3
—
—
—
0
0
(3021901) Oxygen saturation in Capillary blood
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(4306422)
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3042111) Morphology [Interpretation] in Bone marrow Narrative
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3013290) Carbon dioxide [Partial pressure] in Blood
0
9
0.00
-0.00
0.0
3.3
—
5.1
—
0
9
(3027544) Mycobacterium sp identified in Sputum by Organism specific culture
0
7
0.00
-0.00
0.0
3.9
—
—
—
0
0
(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
(3015916) Alpha-1-Fetoprotein [Units/volume] in Serum or Plasma
0
7
0.00
-0.00
0.0
1.1
—
531.6
—
0
7
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
(3024928) Oxygen saturation in Venous blood
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
(3027315) Oxygen [Partial pressure] in Blood
0
9
0.00
-0.00
0.0
3.3
—
7.7
—
0
9
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
0
7
0.00
-0.00
0.0
2.1
—
—
—
0
0
(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint MYOSINTERST and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have MYOSINTERST.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

↥

Index endpoint: MYOSINTERST – Interstitial myositis

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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