This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Other and unspecified disorders of skin and subcutaneous tissue related to radiation
L12_SKINRADINAS
phototoxic dermatitis: a form of allergic contact dermatitis in which the allergen must be activated by light to sensitize the allergic response, and to cause a rash or other systemic effects on subsequent exposure. The second and subsequent exposures produce photoallergic skin conditions which are often eczematous. In rare cases the victims die.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
34 |
4. Check minimum number of eventsNone |
34 |
5. Include endpointsNone |
34 |
6. Filter based on genotype QC (FinnGen only) |
34 |
Control definitions (FinnGen only)
- Control exclude
- L12_RADIATIONRELATEDSKIN
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Other and unspecified disorders of skin and subcutaneous tissue related to radiation
based on the number of shared cases.
Similar with more cases:
- Other disorders of skin and subcutaneous tissue related to radiation
- Radiation-related disorders of the skin and subcutaneous tissue
- Diseases of the skin and subcutaneous tissue
- Paracetamol of NSAID medication
- Any operation in hilmo
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 241 | 149 | 92 |
| Only index persons | 190 | 127 | 63 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.00 | 0.00 | 0.00 |
| Only index persons | 0.00 | 0.00 | 0.00 |
| Median age at first event (years) | |||
| Whole population | - | 64.16 | 58.12 |
| Only index persons | 62.58 | 65.65 | 56.38 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 34 | 27 | 7 |
| Unadjusted period prevalence (%) | 0.01 | 0.01 | 0.00 |
| Median age at first event (years) | 58.62 | 58.32 | 59.78 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
No data
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
No data available
Mortality – FinRegistry
↥Association
Association between endpoint L12_SKINRADINAS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_SKINRADINAS | 1.805 [1.08, 3.01] | 0.024 |
| Birth year | 0.99 [0.98, 1.0] | 0.033 |
During the follow-up period (1.1.1998 — 31.12.2019), 54 out of 128 females with L12_SKINRADINAS died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have L12_SKINRADINAS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.114% | No data |
| 5 | 0.848% | No data |
| 10 | 2.234% | No data |
| 15 | 4.074% | No data |
| 20 | 7.251% | No data |
Relationships between endpoints
↥Index endpoint: L12_SKINRADINAS – Other and unspecified disorders of skin and subcutaneous tissue related to radiation
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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