obsolete_alopecia:
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
103 |
4. Check minimum number of eventsNone |
103 |
5. Include endpointsNone |
103 |
6. Filter based on genotype QC (FinnGen only) |
103 |
Control definitions (FinnGen only)
- Control exclude
- L12_DISORDSKINAPPENDIX
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- L66
- Name in latin
- Lichen planopilaris
Similar endpoints
↥List of similar endpoints to
Lichen planopilaris
based on the number of shared cases.
Similar with more cases:
- Cicatricial alopecia [scarring hair loss]
- Disorders of skin appendages
- Diseases of the skin and subcutaneous tissue
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 618 | 485 | 131 |
| Only index persons | 608 | 481 | 127 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.00 |
| Only index persons | 0.02 | 0.02 | 0.00 |
| Median age at first event (years) | |||
| Whole population | 59.19 | 61.81 | 49.78 |
| Only index persons | 59.08 | 61.54 | 49.78 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 103 | 86 | 17 |
| Unadjusted period prevalence (%) | 0.03 | 0.03 | 0.01 |
| Median age at first event (years) | 60.01 | 61.15 | 54.24 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 86
- Matched controls
- 858
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L66.1
ICD-10 Finland
Lichen planopilaris
+∞
121.9
86
*
D07AD01
ATC
clobetasol; topical
29.5
40.3
66
86
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
23.4
30.0
46
40
P01BA02
ATC
hydroxychloroquine; oral
19.7
27.5
45
45
L43.8
ICD-10 Finland
Other lichen planus
41.7
14.1
17
5
L43.9
ICD-10 Finland
Lichen planus, unspecified
59.7
13.3
15
*
D07AC01
ATC
betamethasone; topical
5.6
12.7
56
215
L30.9
ICD-10 Finland
Dermatitis, unspecified
5.9
10.8
34
85
D07AC13
ATC
mometasone; topical
5.0
10.8
45
155
D07AB02
ATC
hydrocortisone butyrate; topical
4.9
10.7
45
156
D05BB02
ATC
acitretin; oral
34.4
9.7
12
*
L66.8
ICD-10 Finland
Other cicatricial alopecia
+∞
8.5
8
*
L66.9
ICD-10 Finland
Cicatricial alopecia, unspecified
+∞
7.4
7
*
J01AA04
ATC
lymecycline; systemic
5.2
7.2
23
56
D07XC01
ATC
betamethasone, combinations; topical
4.5
6.4
23
64
L71.8
ICD-10 Finland
Other rosacea
+∞
6.3
6
*
XQ848
NOMESCO Finland
Dermatological photography
13.9
6.3
10
8
L57.0
ICD-10 Finland
Actinic keratosis
6.3
6.2
16
30
E0000UV
ATC
NA
3.2
6.2
49
253
Mortality – FinRegistry
↥Association
Association between endpoint L12_LICHENPLANO and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have L12_LICHENPLANO.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: L12_LICHENPLANO – Lichen planopilaris
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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