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Acute generalized exanthematous pustulosis

L12_AGEP

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 L27.0#, L53.8
  • Hospital discharge: ICD-9 6959X
  • Hospital discharge: ICD-8 69599
  • Cause of death: ICD-10 L27.0#, L53.8
  • Cause of death: ICD-9 6959X
  • Cause of death: ICD-8 69599

2 out of 7 registries used, show all original rules.

1691

4. Check minimum number of events

None

1691

5. Include endpoints

None

1691

6. Filter based on genotype QC (FinnGen only)

1691

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF7

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 1691 1109 582
Unadjusted period prevalence (%) 0.34 0.38 0.26
Median age at first event (years) 54.97 52.29 60.07

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1515
Matched controls
15151
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L27.0
ICD-10 Finland
Generalized skin eruption due to drugs and medicaments
6234.8
323.0
1318
18
L53.8
ICD-10 Finland
Other specified erythematous conditions
309.2
139.9
140
5
H02AB06
ATC
prednisolone; systemic
3.6
119.3
964
4965
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
5.6
107.9
355
785
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
4.6
73.5
284
722
XQ800
NOMESCO Finland
Prick test
4.9
72.1
260
614
R06AE07
ATC
cetirizine; oral
2.5
64.5
825
4851
J01FF01
ATC
clindamycin; systemic
2.8
64.5
543
2511
L30.9
ICD-10 Finland
Dermatitis, unspecified
3.1
59.0
395
1557
E0000UV
ATC
NA
2.4
55.7
738
4300
L50.0
ICD-10 Finland
Allergic urticaria
8.9
55.2
122
148
XQ802
NOMESCO Finland
Epicutan test
6.1
53.8
155
278
69599
ICD-8 Finland
Erythematous condition, Other and unspecified
+∞
52.4
50
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.3
50.5
738
4436
D07AC01
ATC
betamethasone; topical
2.4
50.5
609
3332
XQ820
NOMESCO Finland
Exposure to medicinal substance
31.2
45.2
60
20
R50.9
ICD-10 Finland
Fever, unspecified
2.9
44.9
312
1234
D07AB08
ATC
desonide; topical
3.2
43.4
257
910
T78.4
ICD-10 Finland
Allergy, unspecified
4.8
42.2
148
332
XQ899
NOMESCO Finland
Other assessment of skin
20.7
36.3
54
27
L50.9
ICD-10 Finland
Urticaria, unspecified
5.2
35.9
116
237
E000001
ATC
NA
2.3
35.2
396
2016
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.0
34.2
219
808
A02BC02
ATC
pantoprazole; systemic
2.0
33.4
979
7317
D07AA02
ATC
hydrocortisone; topical
2.5
31.4
283
1278
Y57
ICD-10 Finland
Adverse effects in the therapeutic use of other and unspecified drugs and medicaments
6.7
30.7
80
125
A46
ICD-10 Finland
Erysipelas
2.6
30.1
246
1051
C01CA24
ATC
epinephrine; parenteral
3.4
29.9
153
481
TPH04
NOMESCO Finland
Cathetrisation of vein
2.2
29.7
353
1825
J01MA12
ATC
levofloxacin; systemic
2.3
29.4
317
1565
XQ801
NOMESCO Finland
Intracutantest
20.0
27.5
41
21
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.9
27.2
526
3294
D07AC13
ATC
mometasone; topical
2.0
26.6
464
2792
D07AB02
ATC
hydrocortisone butyrate; topical
1.9
26.1
474
2891
J01DB01
ATC
cefalexin; oral
2.0
25.2
1234
10441
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
4.1
25.1
100
254
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.5
24.8
215
943
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
2.7
24.4
181
728
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.0
23.8
366
2085
J01MA14
ATC
moxifloxacin; systemic
2.8
23.3
163
632
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
3.6
23.2
109
320
L04AX01
ATC
azathioprine; systemic
3.6
22.4
105
307
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.5
22.4
107
318
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.2
22.2
239
1166
H02AB07
ATC
prednisone; oral
2.2
22.1
247
1225
T88.7
ICD-10 Finland
Unspecified adverse effect of drug or medicament
6.2
22.1
60
100
ZX120
NOMESCO Finland
Intravenous
2.6
22.1
178
748
ZX108
NOMESCO Finland
Inhalation
14.7
21.7
36
25
N02AX02
ATC
tramadol; systemic, rectal
1.7
21.6
608
4224
P01BA02
ATC
hydroxychloroquine; oral
2.6
21.3
165
678
H02AB02
ATC
dexamethasone; systemic
2.5
20.5
175
758
D07AD01
ATC
clobetasol; topical
2.1
20.3
244
1247
J01MA02
ATC
ciprofloxacin; systemic
1.7
20.3
568
3923
A04AA01
ATC
ondansetron; systemic, rectal
3.0
19.9
123
439
Z01.8
ICD-10 Finland
Other specified special examinations
1.9
19.6
336
1972
L23.3
ICD-10 Finland
Allergic contact dermatitis due to drugs in contact with skin
11.9
19.3
35
30
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.9
19.0
80
214
D02AX
ATC
Other emollients and protectives
3.9
19.0
79
209
L04AD01
ATC
ciclosporin; systemic
5.8
19.0
54
96
E000003
ATC
NA
3.3
19.0
100
321
N03AG01
ATC
valproic acid; systemic, rectal
2.9
18.8
117
421
J01DA01
ATC
[U] cefalexin; systemic
1.6
18.7
924
7401
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
2.8
18.6
121
448
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
18.6
425
2741
L04AA06
ATC
mycophenolic acid; systemic
6.7
18.5
47
72
XW000
NOMESCO Finland
Bone marrow biopsy
3.5
18.3
87
258
N02AA05
ATC
oxycodone; systemic
2.1
18.1
218
1110
TQW80
NOMESCO Finland
Local dermatologic skincare
4.4
18.1
66
155
N02BE01
ATC
paracetamol; systemic, rectal
1.8
18.1
1256
11025
C03CA01
ATC
furosemide; systemic
1.8
18.0
397
2525
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.1
18.0
225
1167
R06.0
ICD-10 Finland
Dyspnoea
1.8
17.5
366
2287
L27.2
ICD-10 Finland
Dermatitis due to ingested food
7.4
17.3
41
57
H02AB04
ATC
methylprednisolone; systemic
2.0
17.2
233
1248
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.2
17.0
182
881
L04AX04
ATC
lenalidomide; oral
19.5
16.9
25
13
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.6
16.8
129
528
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
2.6
16.7
129
529
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.0
16.7
224
1193
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
3.0
16.7
101
357
153
Kela drug reimbursment
Lenalidomid
18.1
16.5
25
14
L27.1
ICD-10 Finland
Localized skin eruption due to drugs and medicaments
18.1
16.5
25
14
R03AC02
ATC
salbutamol; inhalant
1.6
16.2
758
5889
E000006
ATC
NA
2.4
16.0
138
600
J05AB11
ATC
valaciclovir; oral
2.0
15.9
208
1093
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
4.8
15.7
52
111
J01FA06
ATC
roxithromycin; oral
1.6
15.5
575
4203
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.8
15.4
331
2078
R06AX27
ATC
desloratadine; oral
1.7
15.4
417
2802
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.5
15.4
124
522
JN4BD
NOMESCO Finland
Extensive body CT
2.2
15.1
165
805
UGC12
NOMESCO Finland
Flexible bronchoscopy
2.4
14.8
125
537
M04AA01
ATC
allopurinol; systemic
2.1
14.7
181
927
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.6
14.6
638
4830
J01FA10
ATC
azithromycin; systemic
1.5
14.6
850
6881
D07BA04
ATC
hydrocortisone and antiseptics; topical
2.1
14.5
174
883
N03AF01
ATC
carbamazepine; oral, rectal
2.9
14.5
89
318
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
4.0
14.5
58
150
E000002
ATC
NA
2.0
14.4
193
1026
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
2.0
14.3
196
1050
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
3.1
14.1
80
270
J01FA09
ATC
clarithromycin; systemic
1.6
14.0
452
3172
J01AA02
ATC
doxycycline; systemic
1.6
14.0
1073
9214
N03AX16
ATC
pregabalin; oral
1.7
13.8
337
2189
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
13.7
516
3756
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.9
13.6
83
296
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.2
13.5
147
713
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.7
13.4
331
2153
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
3.5
13.3
61
177
L40.0
ICD-10 Finland
Psoriasis vulgaris
3.0
13.3
79
277
P01AB01
ATC
metronidazole; oral, rectal
1.5
13.2
564
4223
Z51.5
ICD-10 Finland
Palliative care
2.7
13.1
92
357
T88.6
ICD-10 Finland
Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
16.9
13.0
20
12
L03AA02
ATC
filgrastim; parenteral
3.9
13.0
53
140
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
3.6
12.9
58
166
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.2
12.9
134
640
R01AD08
ATC
fluticasone; nasal
1.6
12.8
407
2828
XQ848
NOMESCO Finland
Dermatological photography
3.7
12.7
54
148
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.8
12.7
248
1502
J05AB01
ATC
aciclovir; systemic
1.7
12.7
311
2017
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.5
12.6
571
4318
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.2
12.6
136
658
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
4.0
12.6
50
129
6959X
ICD-9 Finland
Erythematous conditions, Unspecified erythematous condition
+∞
12.5
12
*
R06AE09
ATC
levocetirizine; oral
1.8
12.5
218
1270
L51.0
ICD-10 Finland
Nonbullous erythema multiforme
24.5
12.5
17
7
N03AX14
ATC
levetiracetam; systemic
3.7
12.4
54
151
R03BA02
ATC
budesonide; inhalant
1.7
12.4
260
1610
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
3.0
12.3
70
238
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.2
12.2
132
641
A03FA01
ATC
metoclopramide; systemic, rectal
1.7
12.2
299
1938
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.7
12.2
290
1865
L51.9
ICD-10 Finland
Erythema multiforme, unspecified
16.0
12.1
19
12
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.9
12.1
176
962
L26
ICD-10 Finland
Exfoliative dermatitis
18.2
12.1
18
10
ZXD05
NOMESCO Finland
Urgent procedure
1.5
11.7
431
3095
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
11.6
614
4776
J02AC01
ATC
fluconazole; systemic
1.5
11.6
567
4340
L50.8
ICD-10 Finland
Other urticaria
4.1
11.5
44
110
SPAT1263
SPAT
Sampling
1.5
11.5
612
4765
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.5
11.3
470
3464
NF1AA
NOMESCO Finland
Hip X-ray examination
2.1
11.3
131
654
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
3.5
11.2
52
154
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.0
11.1
151
807
A07EC01
ATC
sulfasalazine; oral, rectal
2.1
11.1
126
626
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
4.1
11.0
42
105
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.3
11.0
98
435
1CX01
NOMESCO Finland
NA
43.6
10.9
13
*
B01AB05
ATC
enoxaparin; parenteral
1.5
10.8
398
2849
N03AF02
ATC
oxcarbazepine; oral
3.0
10.7
62
215
A02BC05
ATC
esomeprazole; systemic
1.5
10.6
530
4050
XG410
NOMESCO Finland
Flow-volume spirometry
2.8
10.6
68
252
R03DC03
ATC
montelukast; oral
1.7
10.6
228
1415
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
6.4
10.6
27
43
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
2.2
10.5
106
499
WX002
NOMESCO Finland
Sedation and analgesia
1.7
10.5
264
1716
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
3.6
10.4
46
131
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.6
10.4
270
1767
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.5
10.4
83
348
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.7
10.4
246
1574
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
6.4
10.3
26
41
WW500
NOMESCO Finland
Blood transfusion
2.7
10.3
70
269
N03AX12
ATC
gabapentin; oral
1.7
10.3
214
1318
D05BB02
ATC
acitretin; oral
3.7
10.2
43
118
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.8
10.2
180
1050
C90.0
ICD-10 Finland
Multiple myeloma
6.3
10.2
26
42
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
2.6
10.1
71
277
N03AX09
ATC
lamotrigine; oral
2.5
10.1
78
323
N05BA04
ATC
oxazepam; oral
1.5
10.0
341
2395
J45.9
ICD-10 Finland
Asthma, unspecified
1.7
9.9
246
1589
D07XC01
ATC
betamethasone, combinations; topical
1.8
9.9
162
922
JN4AD
NOMESCO Finland
Body CT examination
2.1
9.9
108
526
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
2.0
9.9
131
690
C07AB07
ATC
bisoprolol; oral
1.4
9.8
586
4624
TPX10
NOMESCO Finland
Implantation of vascular injection port
3.1
9.8
51
166
9940/3-C42.1
ICD-O-3
Hairy cell leukemia, NOS, of bone marrow
55.3
9.7
11
*
L27.9
ICD-10 Finland
Dermatitis due to unspecified substance taken internally
55.3
9.7
11
*
C91.4
ICD-10 Finland
Hairy-cell leukaemia
55.3
9.7
11
*
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
9.6
559
4385
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
9.5
360
2582
Z3231
NOMESCO Finland
Registered nurse
1.5
9.5
375
2715
N17.9
ICD-10 Finland
Acute renal failure, unspecified
2.8
9.5
59
213
R01AD09
ATC
mometasone; nasal
1.4
9.5
612
4891
AA1AD
NOMESCO Finland
CT of head and brain
1.6
9.5
307
2125
L40.1
ICD-10 Finland
Generalized pustular psoriasis
100.6
9.4
10
*
L20.9
ICD-10 Finland
Atopic dermatitis, unspecified
2.7
9.4
63
239
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
3.3
9.4
46
143
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.6
9.4
236
1534
X59
ICD-10 Finland
Exposure to unspecified factor
1.6
9.3
241
1579
A03
ICPC
Fever
1.6
9.2
240
1574
Z71.8
ICD-10 Finland
Other specified counselling
1.5
9.2
325
2295
S97
ICPC
Chronic ulcer skin
2.3
9.1
81
360
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.3
9.1
81
360
L04AB04
ATC
adalimumab; parenteral
3.5
9.1
40
115
M54.5
ICD-10 Finland
Low back pain
1.5
9.1
435
3275
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.8
9.0
149
851
L50.1
ICD-10 Finland
Idiopathic urticaria
7.1
9.0
21
30
L20.0
ICD-10 Finland
Besnier prurigo
2.0
9.0
110
562
H02AB09
ATC
hydrocortisone; systemic
3.2
9.0
45
143
ZXE00
NOMESCO Finland
One hour or less
1.4
8.9
545
4300
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
3.5
8.9
39
112
L30.3
ICD-10 Finland
Infective dermatitis
2.9
8.9
53
190
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
2.0
8.8
119
634
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
4.0
8.8
33
83
127
Kela drug reimbursment
Transplant complication
4.4
8.7
30
69
E66.01
ICD-10 Finland
Obesity due to excess calories
2.0
8.7
107
550
SPAT1255
SPAT
Intravenous administration of medicine
2.1
8.7
95
462
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.7
8.7
204
1296
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
2.7
8.7
57
216
A02BC03
ATC
lansoprazole; oral
1.5
8.7
392
2912
R06AX22
ATC
ebastine; oral
1.6
8.7
235
1553
Z88.1
ICD-10 Finland
Personal history of allergy to other antibiotic agents
50.3
8.7
10
*
G40.9
ICD-10 Finland
Epilepsy, unspecified
2.8
8.7
52
187
M05BX04
ATC
denosumab; parenteral
2.4
8.7
73
318
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.5
8.6
361
2638
J01XX08
ATC
linezolid; systemic
7.7
8.6
19
25
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.4
8.6
69
291
S88
ICPC
Dermatitis contact/allergic
3.3
8.6
42
131
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
2.7
8.6
55
205
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
3.0
8.6
49
168
JN3AD
NOMESCO Finland
Abdominal CT examination
2.0
8.6
103
523
D02AE01
ATC
carbamide; topical
2.0
8.6
101
510
L04AA01
ATC
[U] ciclosporin; systemic
3.9
8.6
33
85
S18
ICPC
Laceration/cut
1.4
8.4
546
4342
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.7
8.4
173
1061
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.9
8.4
124
683
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.6
8.4
219
1435
A04AA02
ATC
granisetron; systemic, transdermal
2.2
8.4
88
422
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.9
8.4
131
735
J45.1
ICD-10 Finland
Nonallergic asthma
2.0
8.4
104
538
ZX112
NOMESCO Finland
Subcutaneous
3.5
8.3
37
108
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
4.8
8.3
26
55
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
2.4
8.2
69
297
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.2
8.2
83
393
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
2.9
8.2
47
163
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
2.8
8.2
52
193
C08CA01
ATC
amlodipine; oral
1.4
8.1
425
3247
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.4
8.0
386
2897
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.7
8.0
175
1092
A28
ICPC
Limited function/disability NOS
1.7
8.0
186
1181
S01GX01
ATC
cromoglicic acid; ophthalmic
1.5
8.0
274
1915
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
2.3
8.0
68
298
9732/3-C42.1
ICD-O-3
Plasma cell myeloma of bone marrow
7.3
8.0
18
25
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
3.1
7.9
41
134
M79.6
ICD-10 Finland
Pain in limb
1.4
7.9
474
3707
M07.3*L40.5
ICD-10 Finland
Other psoriatic arthropathies
3.6
7.9
34
97
329
Kela drug reimbursment
Lenalidomide
13.1
7.9
13
10
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.3
7.9
72
325
D07CC01
ATC
betamethasone and antibiotics; topical
1.7
7.9
174
1091
UJF32
NOMESCO Finland
Coloscopy
1.5
7.8
328
2394
R07.4
ICD-10 Finland
Chest pain, unspecified
1.5
7.8
330
2412
L04AA13
ATC
leflunomide; oral
3.0
7.7
44
151
XF400
NOMESCO Finland
ECG with 12 standard connections
1.6
7.7
207
1365
H66.0
ICD-10 Finland
Acute suppurative otitis media
1.9
7.7
106
569
R60.0
ICD-10 Finland
Localized oedema
1.7
7.7
144
858
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
3.1
7.6
39
127
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
3.9
7.6
29
75
SPAT1254
SPAT
Administration of medicine
1.6
7.6
209
1389
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
3.0
7.5
40
134
N05BB01
ATC
hydroxyzine; systemic
2.0
7.5
97
508
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.3
7.5
65
288
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
3.6
7.5
32
91
R11
ICD-10 Finland
Nausea and vomiting
1.8
7.5
116
651
TK800
NOMESCO Finland
Hemodialysis
3.4
7.4
34
102
TDM10
NOMESCO Finland
Puncture of maxillary antrum
2.4
7.4
62
270
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.1
7.4
82
406
M25.5
ICD-10 Finland
Pain in joint
1.4
7.4
372
2811
M13.9
ICD-10 Finland
Arthritis, unspecified
2.0
7.4
96
503
TGC00
NOMESCO Finland
Bronchial lavation
3.2
7.4
37
119
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.4
7.4
379
2874
R4110
NOMESCO Finland
Physiotherapy
1.4
7.4
339
2520
M05BA04
ATC
alendronic acid; oral
1.8
7.3
115
647
D86.1
ICD-10 Finland
Sarcoidosis of lymph nodes
8.4
7.3
15
18
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.6
7.3
196
1292
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
9.4
7.3
14
15
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
1.9
7.3
107
590
EMB30
NOMESCO Finland
Adenotomy
2.6
7.2
50
196
N05CF01
ATC
zopiclone; oral
1.4
7.1
411
3183
D64.9
ICD-10 Finland
Anaemia, unspecified
1.8
7.1
124
724
D07CA01
ATC
hydrocortisone and antibiotics; topical
1.6
7.1
174
1119
134
Kela drug reimbursment
General erythroderma
12.1
7.1
12
10
A02BA02
ATC
ranitidine; systemic
1.5
7.1
246
1724
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
8.8
7.0
14
16
A92
ICPC
Allergy/allergic reaction NOS
2.5
7.0
52
211
A41.9
ICD-10 Finland
Sepsis, unspecified
2.5
7.0
52
211
R02
ICPC
Shortness of breath/dyspnoea
1.7
7.0
159
1003
GD1AD
NOMESCO Finland
Thorax CT examination
2.4
7.0
58
251
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
3.2
6.9
34
108
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.6
6.9
186
1226
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.7
6.9
142
870
A02BC01
ATC
omeprazole; systemic
1.4
6.9
351
2656
J01CA04
ATC
amoxicillin; systemic
1.4
6.8
1153
10562
S76
ICPC
Skin infection other
2.1
6.8
70
334
128
Kela drug reimbursment
Cancers of female genital organs
3.5
6.8
30
88
T78.2
ICD-10 Finland
Anaphylactic shock, unspecified
4.2
6.8
24
58
B01AC04
ATC
clopidogrel; oral
1.6
6.8
180
1184
R51.80
ICD-10 Finland
Headache
1.6
6.8
202
1367
I10
ICD-10 Finland
Essential (primary) hypertension
1.3
6.8
688
5828
WW200
NOMESCO Finland
Immunization
2.6
6.7
47
185
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.1
6.7
69
330
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.4
6.7
351
2671
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
1.9
6.7
98
539
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.6
6.6
159
1018
H05AA02
ATC
teriparatide; parenteral
6.5
6.6
16
25
XG474
NOMESCO Finland
Exhalation nntrogen oxide
2.7
6.6
43
163
B01AB10
ATC
tinzaparin; parenteral
1.9
6.6
94
513
M01CB01
ATC
sodium aurothiomalate; parenteral
3.8
6.6
26
70
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.7
6.6
126
757
R53
ICD-10 Finland
Malaise and fatigue
1.5
6.6
268
1938
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.5
6.6
211
1452
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.3
6.6
687
5835
I83.1
ICD-10 Finland
Varicose veins of lower extremities with inflammation
3.3
6.6
30
91
R81
ICPC
Pneumonia
2.6
6.5
44
172
D07BC01
ATC
betamethasone and antiseptics; topical
1.6
6.5
155
991
D47.2
ICD-10 Finland
Monoclonal gammopathy of undetermined significance (MGUS)
5.0
6.5
19
38
R42
ICD-10 Finland
Dizziness and giddiness
1.4
6.5
280
2050
L52
ICD-10 Finland
Erythema nodosum
5.3
6.5
18
34
L30.0
ICD-10 Finland
Nummular dermatitis
2.5
6.5
47
192
J47
ICD-10 Finland
Bronchiectasis
3.5
6.4
28
82
6960A
ICD-9 Finland
Psoriasis and similar disorders, Psoriatic arthropathy
14.4
6.4
10
7
R03AC03
ATC
terbutaline; inhalant
1.6
6.4
186
1248
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
3.7
6.4
26
72
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
6.4
466
3743
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.0
6.4
82
429
317
Kela drug reimbursment
Topical pimecrolimus and tacrolimus
3.3
6.4
29
88
ZYC05
NOMESCO Finland
Non-real-time text-based remote communication
6.6
6.3
15
23
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
2.3
6.3
54
238
L93.0
ICD-10 Finland
Discoid lupus erythematosus
6.0
6.3
16
27
ZYC01
NOMESCO Finland
Remote contact by phone
2.1
6.3
64
305
K12.10
ICD-10 Finland
Stomatitis NOS
11.1
6.3
11
10
A07AA02
ATC
nystatin; oral
1.9
6.3
84
449
C91.0
ICD-10 Finland
Acute lymphoblastic leukaemia [ALL]
9.3
6.3
12
13
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.2
6.3
62
294
UDH02
NOMESCO Finland
Rhinopharyngoscopy
1.9
6.2
89
485
Z96.1
ICD-10 Finland
Presence of intraocular lens
1.6
6.2
153
986
SPAT1262
SPAT
Handing over of treatment supplies
1.5
6.2
215
1505
A07AA09
ATC
vancomycin; oral
4.5
6.2
20
45
X57
ICD-10 Finland
Unspecified privation
3.0
6.1
33
113
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
1.8
6.1
110
646
318
Kela drug reimbursment
Teriparatide
5.8
6.1
16
28
M05BB03
ATC
alendronic acid and colecalciferol; oral
2.9
6.1
35
122
WZC30
NOMESCO Finland
Teaching
1.6
6.1
161
1058
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.5
6.1
207
1442
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.6
6.1
174
1164
M03BX02
ATC
tizanidine; oral
1.3
6.1
789
6883
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
4.9
6.0
18
37
L04AC05
ATC
ustekinumab; parenteral
10.1
6.0
11
11
N03AX18
ATC
lacosamide; systemic
5.2
6.0
17
33

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: L12_AGEP – Acute generalized exanthematous pustulosis

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).