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Acne vulgaris

L12_ACNE_VULGARIS

acne: An inflammatory process of the sebaceous glands which is characterized by comedones, nodules, papules and/or pustules on the skin.

Suggest a new description

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 L70.0
  • Hospital discharge: ICD-9 7061A
  • Hospital discharge: ICD-8 70610
  • Cause of death: ICD-10 L70.0
  • Cause of death: ICD-9 7061A
  • Cause of death: ICD-8 70610

2 out of 7 registries used, show all original rules.

3755

4. Check minimum number of events

None

3755

5. Include endpoints

None

3755

6. Filter based on genotype QC (FinnGen only)

3755

Control definitions (FinnGen only)

Control exclude
L12_DISORDSKINAPPENDIX

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
L70
Name in latin
Acne vulgaris

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 3755 2382 1373
Unadjusted period prevalence (%) 0.74 0.81 0.61
Median age at first event (years) 23.57 25.65 19.97

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
3249
Matched controls
32488
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
J01AA04
ATC
lymecycline; systemic
7.1
323.0
1367
3005
D10BA01
ATC
isotretinoin; oral
18.4
323.0
1808
2076
L70.0
ICD-10 Finland
Acne vulgaris
631.6
323.0
3016
655
J01AA07
ATC
tetracycline; systemic
8.9
323.0
1633
3305
D10AX03
ATC
azelaic acid; topical
6.0
314.1
1015
2281
G03HB01
ATC
cyproterone and estrogen; systemic
4.2
190.7
856
2547
70610
ICD-8 Finland
Diseases of sebaceous glands, Acne vulgaris
+∞
180.9
172
*
L70
ICD-10 Finland
Acne
7.7
171.2
427
630
E0000UV
ATC
NA
2.8
169.9
1708
9108
D10AF01
ATC
clindamycin; topical
5.5
132.6
423
854
E000001
ATC
NA
2.8
124.4
1030
4630
L70.1
ICD-10 Finland
Acne conglobata
43.9
111.8
139
33
S96
ICPC
Acne
6.2
104.6
301
529
L73.2
ICD-10 Finland
Hidradenitis suppurativa
35.2
101.3
132
39
L70.9
ICD-10 Finland
Acne, unspecified
16.0
96.3
160
105
E0001A1
ATC
NA
5.5
84.7
266
518
7061A
ICD-9 Finland
Diseases of sebaceous glands, Other acne[ACNE VULGARIS]
+∞
77.4
74
*
XQ848
NOMESCO Finland
Dermatological photography
8.7
58.8
131
157
L70.8
ICD-10 Finland
Other acne
21.3
57.2
85
41
L73.8
ICD-10 Finland
Other specified follicular disorders
18.5
54.6
85
47
D06BX01
ATC
metronidazole; topical
3.2
54.3
313
1055
L72.1
ICD-10 Finland
Trichilemmal cyst
4.7
47.5
168
371
L71.8
ICD-10 Finland
Other rosacea
21.0
47.1
70
34
L71.9
ICD-10 Finland
Rosacea, unspecified
7.9
41.1
96
125
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.2
38.7
216
708
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.8
38.7
757
4604
N06AX11
ATC
mirtazapine; oral
1.7
35.3
828
5315
D10AD01
ATC
tretinoin; topical
4.3
33.2
126
299
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.9
31.4
511
2888
D07AB02
ATC
hydrocortisone butyrate; topical
1.7
31.3
792
5169
TQW80
NOMESCO Finland
Local dermatologic skincare
5.3
31.0
97
188
J01FF01
ATC
clindamycin; systemic
1.8
30.6
674
4212
J01DB01
ATC
cefalexin; oral
1.6
29.3
2526
22194
N05BA04
ATC
oxazepam; oral
1.7
28.9
648
4064
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.8
28.0
554
3334
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
2.0
28.0
407
2201
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
27.5
530
3161
D07AC01
ATC
betamethasone; topical
1.6
27.3
793
5344
H02AB06
ATC
prednisolone; systemic
1.6
27.1
1072
7812
J02AC01
ATC
fluconazole; systemic
1.6
26.7
1070
7814
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.1
26.4
341
1755
N05AH04
ATC
quetiapine; oral
1.7
26.3
623
3962
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.9
25.8
439
2506
N06AX16
ATC
venlafaxine; oral
1.8
25.8
463
2694
S10
ICPC
Boil/carbuncle
2.7
25.4
180
689
N05CF01
ATC
zopiclone; oral
1.7
24.2
553
3471
XQ800
NOMESCO Finland
Prick test
2.0
23.9
311
1604
L20.0
ICD-10 Finland
Besnier prurigo
1.9
23.9
380
2117
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
23.8
770
5306
D07AB08
ATC
desonide; topical
2.0
23.6
332
1766
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.7
23.5
508
3132
Z94.0
ICD-10 Finland
Kidney transplant status
6.8
22.9
58
87
A02BC02
ATC
pantoprazole; systemic
1.5
22.8
1366
10788
C03DA01
ATC
spironolactone; oral
2.9
22.6
145
522
D07XC01
ATC
betamethasone, combinations; topical
2.1
22.3
253
1231
N06AB04
ATC
citalopram; systemic
1.7
22.1
498
3101
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.4
21.3
180
760
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
21.2
519
3310
L04AA06
ATC
mycophenolic acid; systemic
5.0
20.7
67
137
N03AX16
ATC
pregabalin; oral
1.8
20.6
425
2572
UJF32
NOMESCO Finland
Coloscopy
1.8
20.6
408
2443
L73.9
ICD-10 Finland
Follicular disorder, unspecified
17.0
20.5
32
19
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
2.6
20.3
156
627
TQW99
NOMESCO Finland
Other minor procedure on skin
3.7
20.3
91
254
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
19.8
1344
10773
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.7
19.8
411
2495
J04BA02
ATC
dapsone; oral
15.4
19.7
32
21
L71.0
ICD-10 Finland
Perioral dermatitis
3.9
19.7
81
210
N02AX02
ATC
tramadol; systemic, rectal
1.5
19.6
753
5372
N03AX12
ATC
gabapentin; oral
1.9
19.5
285
1536
D07BA04
ATC
hydrocortisone and antiseptics; topical
1.7
19.5
416
2544
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
2.8
19.2
125
454
N02BE01
ATC
paracetamol; systemic, rectal
1.4
19.1
2274
20136
J01FA01
ATC
erythromycin; systemic
1.6
18.9
574
3866
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
5.2
18.9
59
116
XQ802
NOMESCO Finland
Epicutan test
2.6
18.8
140
554
L40.0
ICD-10 Finland
Psoriasis vulgaris
2.9
18.8
116
410
L04AX01
ATC
azathioprine; systemic
2.5
18.5
154
646
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.7
17.9
367
2215
127
Kela drug reimbursment
Transplant complication
4.7
17.8
61
133
R06AE07
ATC
cetirizine; oral
1.4
17.8
1368
11146
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
17.7
1034
8010
L04AD01
ATC
ciclosporin; systemic
4.0
17.7
71
181
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
1.9
17.3
280
1564
J01MA02
ATC
ciprofloxacin; systemic
1.5
17.3
722
5227
N05AX08
ATC
risperidone; systemic
2.0
17.2
221
1131
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
8.2
17.2
38
47
S29
ICPC
Skin symptom/complaint other
1.7
17.2
420
2669
L02.0
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of face
4.3
17.1
63
148
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
4.6
16.9
58
127
N06AB10
ATC
escitalopram; oral
1.5
16.7
700
5062
Z3231
NOMESCO Finland
Registered nurse
1.5
16.7
663
4737
N06AB03
ATC
fluoxetine; oral
1.7
16.6
331
1979
L91.0
ICD-10 Finland
Hypertrophic scar
3.5
16.3
75
215
SPAT1301
SPAT
No procedures
1.4
16.2
874
6648
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
7.0
16.1
39
56
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.4
16.0
946
7315
137
Kela drug reimbursment
Uraemia requiring dialysis
7.5
15.9
37
50
N06AB06
ATC
sertraline; oral
1.7
15.9
379
2389
R50.9
ICD-10 Finland
Fever, unspecified
1.6
15.8
395
2520
A02BC03
ATC
lansoprazole; oral
1.6
15.7
459
3054
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
2.6
15.6
113
442
N03AX09
ATC
lamotrigine; oral
2.0
15.5
199
1019
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
2.1
15.4
180
889
L68.0
ICD-10 Finland
Hirsutism
9.0
15.4
32
36
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
2.4
15.3
130
554
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.4
15.1
948
7391
N06AX12
ATC
bupropion; oral
1.8
15.1
262
1499
E000007
ATC
NA
2.0
15.1
203
1062
L21.9
ICD-10 Finland
Seborrhoeic dermatitis, unspecified
4.0
15.0
59
148
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
6.1
15.0
40
66
A06AD11
ATC
lactulose; oral
2.0
14.9
193
992
J01AA02
ATC
doxycycline; systemic
1.3
14.9
1694
14554
J01DA01
ATC
[U] cefalexin; systemic
1.3
14.8
1645
14075
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
1.9
14.8
228
1254
D07AC13
ATC
mometasone; topical
1.5
14.7
648
4721
R03AC02
ATC
salbutamol; inhalant
1.3
14.7
1460
12271
D07AD01
ATC
clobetasol; topical
1.8
14.7
283
1675
SDA02
NOMESCO Finland
Parodonthologic therapy
1.4
14.7
991
7823
B03XA02
ATC
darbepoetin alfa; parenteral
5.6
14.6
42
76
D05BB02
ATC
acitretin; oral
4.9
14.5
47
98
N06AX21
ATC
duloxetine; oral
1.8
14.5
253
1452
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
2.0
14.4
185
947
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
1.8
14.4
247
1405
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
14.4
1411
11820
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
6.2
14.4
38
62
L04AA01
ATC
[U] ciclosporin; systemic
4.8
14.3
47
99
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.4
14.3
121
514
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
2.3
14.3
132
585
D06AX01
ATC
fusidic acid; topical (antibiotics for topical use)
1.7
14.3
313
1925
WZC30
NOMESCO Finland
Teaching
1.8
14.3
233
1303
L21.8
ICD-10 Finland
Other seborrhoeic dermatitis
5.1
14.2
44
87
TK800
NOMESCO Finland
Hemodialysis
4.1
14.2
55
137
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.7
14.1
286
1720
M25.5
ICD-10 Finland
Pain in joint
1.4
13.9
694
5177
SAA02
NOMESCO Finland
Basic examination of mouth
1.4
13.9
2353
21384
WX110
NOMESCO Finland
Local anesthesy
1.3
13.8
2219
19978
L21.0
ICD-10 Finland
Seborrhoea capitis
5.1
13.8
43
86
380
Kela drug reimbursment
Adalimumab (hidradenitis suppurativa)
+∞
13.5
13
*
D02AE01
ATC
carbamide; topical
2.0
13.5
182
951
R06.0
ICD-10 Finland
Dyspnoea
1.5
13.5
446
3048
E000002
ATC
NA
1.6
13.5
398
2648
N06AB05
ATC
paroxetine; oral
2.0
13.3
162
815
C03CA01
ATC
furosemide; systemic
1.9
13.2
198
1076
N05CD07
ATC
temazepam; oral
2.3
13.2
122
540
H04AA01
ATC
glucagon; nasal, parenteral
2.2
13.2
128
583
Z71.8
ICD-10 Finland
Other specified counselling
1.4
13.0
764
5859
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
12.8
2312
21042
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
6.6
12.8
32
49
ZX120
NOMESCO Finland
Intravenous
1.9
12.7
182
976
L02
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle
2.3
12.7
114
502
L02.2
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of trunk
2.4
12.6
104
436
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.9
12.6
185
998
Z3226
NOMESCO Finland
Physiotherapist
1.5
12.6
397
2684
A06AC01
ATC
ispaghula (psylla seeds); oral
1.6
12.5
375
2502
A02BC01
ATC
omeprazole; systemic
1.5
12.5
494
3509
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.0
12.4
155
787
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
1.8
12.4
204
1148
L90.5
ICD-10 Finland
Scar conditions and fibrosis of skin
4.8
12.3
40
84
L20.9
ICD-10 Finland
Atopic dermatitis, unspecified
2.1
12.2
142
700
L70.5
ICD-10 Finland
Acné excoriée
37.7
12.2
15
*
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
4.9
12.0
38
78
P01AB01
ATC
metronidazole; oral, rectal
1.4
12.0
890
7086
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
2.6
12.0
84
325
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
1.8
11.9
222
1301
A03FA01
ATC
metoclopramide; systemic, rectal
1.6
11.9
365
2448
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
4.7
11.8
39
84
SPAT1260
SPAT
Consultation of another employee
1.5
11.8
462
3273
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
3.0
11.7
68
233
C07AA05
ATC
propranolol; systemic
1.4
11.7
531
3871
M79.6
ICD-10 Finland
Pain in limb
1.4
11.7
784
6135
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.0
11.7
143
720
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
3.4
11.7
55
163
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
4.6
11.7
39
85
SPAT1263
SPAT
Sampling
1.3
11.6
1268
10677
A10AB04
ATC
insulin lispro; parenteral (insulins and analog. for injection, fast-acting)
2.2
11.6
112
511
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.0
11.6
153
797
H3603, E103
ICD-10 Finland
NA
4.1
11.6
44
109
L03.0
ICD-10 Finland
Cellulitis of finger and toe
1.8
11.5
195
1107
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.5
11.5
430
3012
R21
ICPC
Throat symptom/complaint
1.3
11.3
971
7889
D01
ICPC
Abdominal pain/cramps general
1.5
11.3
402
2788
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.3
11.2
1029
8441
UKC02
NOMESCO Finland
Cystoscopy
1.8
11.2
179
995
Z49.1
ICD-10 Finland
Extracorporeal dialysis
4.7
11.2
37
80
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
1.5
11.2
405
2822
Z49.2
ICD-10 Finland
Other dialysis
6.8
11.1
27
40
T36
ICD-10 Finland
Poisoning by systemic antibiotics
1.9
11.1
171
941
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
11.1
425
2993
N06AA09
ATC
amitriptyline; systemic
2.1
11.1
121
584
B05DA
ATC
Isotonic solutions
6.4
11.1
28
44
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
1.9
11.0
165
900
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.3
11.0
1727
15235
N05AX12
ATC
aripiprazole; systemic
1.8
10.9
182
1030
R53
ICD-10 Finland
Malaise and fatigue
1.4
10.8
504
3693
B05DB
ATC
Hypertonic solutions
7.2
10.7
25
35
L63.8
ICD-10 Finland
Other alopecia areata
28.1
10.7
14
5
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.5
10.7
327
2192
R11
ICD-10 Finland
Nausea and vomiting
1.7
10.7
221
1337
R4110
NOMESCO Finland
Physiotherapy
1.4
10.7
509
3744
N05BA01
ATC
diazepam; systemic, rectal
1.6
10.6
256
1615
A10AE05
ATC
insulin detemir; parenteral
2.0
10.6
131
665
XCK10
NOMESCO Finland
Photography of fundus of eye
1.9
10.6
153
821
F43.1
ICD-10 Finland
Post-traumatic stress disorder
2.0
10.6
126
630
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
10.6
1698
14988
T89
ICPC
Diabetes insulin dependent
2.0
10.5
136
700
M79.1
ICD-10 Finland
Myalgia
1.5
10.5
338
2291
N05AH03
ATC
olanzapine; systemic
1.7
10.5
214
1287
SPAT1240
SPAT
Therapeutic discussion
1.4
10.5
483
3532
WQ031
NOMESCO Finland
NA
+∞
10.4
10
*
A10AE04
ATC
insulin glargine; parenteral
1.8
10.4
167
932
N06AX22
ATC
agomelatine; oral
2.4
10.3
89
383
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
2.1
10.3
115
560
C07AB07
ATC
bisoprolol; oral
1.4
10.3
504
3725
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
1.8
10.2
167
938
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
1.4
10.2
435
3134
A05
ICPC
Feeling ill
1.5
10.1
349
2401
B03XA01
ATC
erythropoietin; parenteral
7.9
10.1
22
28
S18
ICPC
Laceration/cut
1.3
10.1
824
6628
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
3.2
10.0
50
156
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.4
10.0
536
4024
E000008
ATC
NA
6.1
10.0
26
43
A63.0
ICD-10 Finland
Anogenital (venereal) warts
1.8
9.9
183
1071
A02BC05
ATC
esomeprazole; systemic
1.3
9.9
720
5688
SPAT1249
SPAT
Treatment-related counselling outside office
1.3
9.9
1169
9886
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
7.6
9.9
22
29
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
2.2
9.9
100
468
N06AX26
ATC
vortioxetine; oral
1.7
9.9
206
1249
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
5.0
9.8
30
60
J01MA12
ATC
levofloxacin; systemic
1.6
9.8
260
1682
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
1.8
9.8
167
954
WZA90
NOMESCO Finland
Other doctors statement
1.3
9.7
740
5889
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
2.2
9.7
94
433
L73.0
ICD-10 Finland
Acne keloid
55.2
9.6
11
*
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.3
9.6
1530
13426
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
1.6
9.6
261
1702
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.5
9.6
301
2031
K59.1
ICD-10 Finland
Functional diarrhoea
2.1
9.5
109
536
M05BA04
ATC
alendronic acid; oral
3.3
9.5
47
146
H04.10
ICD-10 Finland
Dry eye syndrome
1.8
9.5
172
997
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
9.5
1438
12530
C09CA06
ATC
candesartan; oral
1.5
9.5
312
2124
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
4.0
9.5
36
90
J04AB02
ATC
rifampicin; systemic
5.2
9.5
28
54
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
6.0
9.5
25
42
K02.1
ICD-10 Finland
Caries of dentine
1.3
9.5
1934
17470
J01EA01
ATC
trimethoprim; systemic
1.4
9.4
518
3904
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
1.9
9.4
136
734
A12AA04
ATC
calcium carbonate; oral
4.1
9.4
35
86
M01AE02
ATC
naproxen; oral, rectal
1.3
9.4
1655
14681
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.5
9.3
294
1985
L02.9
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle, unspecified
2.3
9.3
85
377
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.4
9.3
449
3305
196
Kela drug reimbursment
Paricalcitol and cinacalcet
6.9
9.3
22
32
L01
ICPC
Neck symptom/complaint
1.5
9.3
360
2541
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
9.3
591
4568
QDA25
NOMESCO Finland
Destruction of lesion of skin of lower limb
8.7
9.3
19
22
D07CC01
ATC
betamethasone and antibiotics; topical
1.5
9.3
287
1928
L71
ICD-10 Finland
Rosacea
3.1
9.2
49
161
S21
ICPC
Skin texture symptom/complaint
1.5
9.2
281
1883
J45.9
ICD-10 Finland
Asthma, unspecified
1.5
9.2
381
2723
N18.8
ICD-10 Finland
Other chronic renal failure
3.6
9.2
40
113
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
4.4
9.2
32
74
Z01.9
ICD-10 Finland
Special examination, unspecified
2.1
9.2
104
510
SHA01
NOMESCO Finland
Correction of physiology of bite - simple therapy visit
1.5
9.2
315
2169
H02AB09
ATC
hydrocortisone; systemic
2.4
9.2
73
305
L17
ICPC
Foot/toe symptom/complaint
1.4
9.1
580
4477
ZXA00
NOMESCO Finland
Right side
1.5
9.1
377
2692
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
1.4
9.1
503
3793
H43.1
ICD-10 Finland
Vitreous haemorrhage
3.9
9.1
36
94
L02.3
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of buttock
2.4
9.1
73
307
N03AG01
ATC
valproic acid; systemic, rectal
1.8
9.1
166
968
K07.60
ICD-10 Finland
Snapping jaw
1.7
9.0
166
972
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.7
9.0
183
1102
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.5
9.0
364
2590
N06AA12
ATC
doxepin; systemic
2.4
9.0
74
313
D02AX
ATC
Other emollients and protectives
2.0
8.9
107
539
N03AE01
ATC
clonazepam; systemic
2.0
8.9
109
554
SDA03
NOMESCO Finland
Demanding parodonthologic therapy
1.3
8.9
982
8211
V03AE02
ATC
sevelamer; oral
5.7
8.9
24
42
XCW99
NOMESCO Finland
Other investigative procedure of eye
1.7
8.8
174
1038
F51.0
ICD-10 Finland
Nonorganic insomnia
1.4
8.8
377
2715
L04AB04
ATC
adalimumab; parenteral
2.4
8.8
70
291
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.4
8.8
541
4155
V03AE03
ATC
lanthanum carbonate; oral
9.5
8.8
17
18
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.7
8.8
56
207
K03.00
ICD-10 Finland
Approximal wear
1.9
8.7
130
708
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
4.1
8.7
32
78
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
2.0
8.7
101
501
A10AD01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)
2.8
8.7
55
200
R02
ICPC
Shortness of breath/dyspnoea
1.6
8.7
248
1632
SHA02
NOMESCO Finland
Correction of physiology of bite - basic therapy visit
1.6
8.7
225
1446
D10AE01
ATC
benzoyl peroxide; topical
14.1
8.7
14
10
N05CF02
ATC
zolpidem; oral
1.5
8.7
344
2441
S97
ICPC
Chronic ulcer skin
2.6
8.7
60
233
L03
ICPC
Low back symptom/complaint
1.3
8.6
620
4873
P01
ICPC
Feeling anxious/nervous/tense
1.3
8.6
576
4476
B07.9
ICD-10 Finland
Verruca simplex
1.9
8.6
119
633
G43.9
ICD-10 Finland
Migraine, unspecified
1.6
8.6
224
1445
ZQX00
NOMESCO Finland
0-4% of the skin
11.6
8.6
15
13
M54.5
ICD-10 Finland
Low back pain
1.3
8.6
810
6629
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
1.9
8.5
118
628
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.2
8.5
1702
15249
G44.2
ICD-10 Finland
Tension-type headache
1.5
8.5
344
2449
K59.09
ICD-10 Finland
Constipation, unspecified
2.1
8.5
92
445
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
2.5
8.4
65
267
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.7
8.4
167
998
TPH04
NOMESCO Finland
Cathetrisation of vein
1.4
8.4
376
2729
WXQ27
NOMESCO Finland
UVB narrow spectrum light therapy
3.4
8.4
39
117
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.2
8.4
1929
17542
A11CC03
ATC
alfacalcidol; systemic
3.0
8.4
46
156
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.7
8.3
175
1065
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
6.2
8.3
21
34
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.0
8.3
102
519
R06AX27
ATC
desloratadine; oral
1.3
8.3
866
7175
N08.39
ICD-10 Finland
Glomerular disorders in diabetes mellitus microalbuminuria
9.5
8.3
16
17
N30.0
ICD-10 Finland
Acute cystitis
1.5
8.2
327
2319
L82
ICD-10 Finland
Seborrhoeic keratosis
1.7
8.2
162
970
M03BC01
ATC
orphenadrine (citrate); systemic
1.3
8.2
552
4297
W78
ICPC
Pregnancy
0.8
8.2
501
6350
R51.80
ICD-10 Finland
Headache
1.4
8.2
465
3522
QBA10
NOMESCO Finland
Incision of skin of trunk
3.4
8.2
37
109
E000006
ATC
NA
1.7
8.2
153
903
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
1.7
8.1
149
871
R42
ICD-10 Finland
Dizziness and giddiness
1.4
8.1
333
2376
W90
ICPC
Uncompl labour/delivery livebirth
0.6
8.1
91
1603
V03AE01
ATC
polystyrene sulfonate; oral
5.4
8.1
23
43
F29
ICD-10 Finland
Unspecified nonorganic psychosis
1.7
8.1
161
965
F45.8
ICD-10 Finland
Other somatoform disorders
1.5
8.1
246
1646
Z37.0
ICD-10 Finland
Single live birth
0.7
8.1
192
2840
N76.0
ICD-10 Finland
Acute vaginitis
1.5
8.0
254
1715
SPAT1310
SPAT
Counselling related to known health issue
1.3
8.0
926
7763
WX002
NOMESCO Finland
Sedation and analgesia
1.5
8.0
305
2147
N05BA12
ATC
alprazolam; oral
1.6
8.0
183
1142
L30.3
ICD-10 Finland
Infective dermatitis
2.2
8.0
81
381
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
2.9
7.9
46
160
A07EC02
ATC
mesalazine; oral, rectal
1.7
7.9
147
862
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
3.2
7.9
40
128
N02AJ06
ATC
codeine and paracetamol; systemic
1.3
7.9
868
7226
SPAT1307
SPAT
Psychosocial counselling and guidance
1.4
7.9
361
2632
M03BX02
ATC
tizanidine; oral
1.2
7.9
1432
12646
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
2.4
7.9
62
259
L02.8
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of other sites
2.7
7.9
51
191
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
1.7
7.9
143
836
J45.1
ICD-10 Finland
Nonallergic asthma
1.7
7.8
160
969
R04.0
ICD-10 Finland
Epistaxis
2.0
7.8
92
462
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.4
7.8
334
2403
P76
ICPC
Depressive disorder
1.5
7.8
244
1645
WX408
NOMESCO Finland
General anesthesy, balanced
1.3
7.8
571
4498
SHA03
NOMESCO Finland
Correction of physiology of bite - demanding therapy visit
2.0
7.8
100
517
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.7
7.8
166
1017
N06AB08
ATC
fluvoxamine; oral
2.8
7.7
46
164
L05.0
ICD-10 Finland
Pilonidal cyst with abscess
2.7
7.7
51
194
CKD40
NOMESCO Finland
Endophotocoagulation of retina
4.4
7.7
26
59
SPAT1312
SPAT
General health counselling
1.2
7.7
1098
9433
P29
ICPC
Psychological sympt/compl other
1.5
7.7
256
1750
M79.7
ICD-10 Finland
Fibromyalgia
2.2
7.7
77
361
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
1.4
7.7
346
2516
R52.9
ICD-10 Finland
Pain, unspecified
1.6
7.7
180
1133
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
2.0
7.6
89
446
RS221
NOMESCO Finland
NA
2.8
7.6
47
172
A46
ICD-10 Finland
Erysipelas
1.7
7.6
163
998
K50.9
ICD-10 Finland
Crohn disease, unspecified
2.5
7.6
54
214
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.5
7.6
256
1755
J01FA06
ATC
roxithromycin; oral
1.3
7.6
801
6635
ZXA05
NOMESCO Finland
Left side
1.4
7.5
348
2542
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.6
7.5
205
1339
N05AA02
ATC
levomepromazine; systemic
2.1
7.5
85
419
H02AB07
ATC
prednisone; oral
1.5
7.5
218
1447
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
1.5
7.5
237
1603
D11AH01
ATC
tacrolimus; topical
2.8
7.4
45
163
L60.0
ICD-10 Finland
Ingrowing nail
1.9
7.4
104
559
SPAT1153
SPAT
Removal of sutures
1.3
7.4
541
4259
A10AA02
ATC
NA
2.1
7.4
80
390
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.3
7.4
468
3607
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.3
7.4
64
281
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
3.3
7.4
35
108
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
3.9
7.3
28
72
N04BC05
ATC
pramipexole; oral
2.1
7.3
77
369
A10AA01
ATC
NA
2.1
7.3
79
382
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.4
7.3
391
2930
L23.2
ICD-10 Finland
Allergic contact dermatitis due to cosmetics
3.3
7.3
34
103
XKD00
NOMESCO Finland
Uroflowmetry
1.7
7.3
138
816
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.5
7.3
210
1389
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.3
7.3
652
5278
N06AX05
ATC
trazodone; oral
2.3
7.3
64
284
103
Kela drug reimbursment
Diabetes, insulin-treated
1.4
7.3
297
2118
H13
ICPC
Plugged feeling ear
1.5
7.2
280
1974
SPAT1262
SPAT
Handing over of treatment supplies
1.5
7.2
263
1830
Z3229
NOMESCO Finland
Other healthcare associate professional
1.7
7.2
154
944
L05.9
ICD-10 Finland
Pilonidal cyst without abscess
2.3
7.2
64
286
ZXA10
NOMESCO Finland
Bilateral
1.4
7.2
322
2338
ZXE10
NOMESCO Finland
More than one and less than three hours
1.3
7.2
683
5577
A07AA02
ATC
nystatin; oral
2.0
7.2
81
402
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
2.0
7.1
85
430
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.2
7.1
961
8183
-1
NOMESCO Finland
NA
1.2
7.1
1250
10961
Z01.2
ICD-10 Finland
Dental examination
1.2
7.1
1310
11547
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
5.0
7.1
21
42
D07AA02
ATC
hydrocortisone; topical
1.3
7.1
457
3528
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.3
7.0
890
7523
N18.0
ICD-10 Finland
End-stage renal disease
4.3
7.0
24
56
205
Kela drug reimbursment
Chronic hypertension
1.6
7.0
157
976
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.6
7.0
199
1311
L23.0
ICD-10 Finland
Allergic contact dermatitis due to metals
3.4
7.0
31
91
S04
ICPC
Lump/swelling localized
1.5
7.0
247
1711
N02AA05
ATC
oxycodone; systemic
1.7
7.0
128
753
MA3AE
NOMESCO Finland
Combined first trimester screening
0.6
7.0
111
1786
KMAK
NOMESCO Finland
NA
1.2
6.9
1541
13836
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
2.0
6.9
83
421
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
0.7
6.9
390
5002
N05BE01
ATC
buspirone; oral
2.2
6.9
66
305
WW200
NOMESCO Finland
Immunization
2.1
6.8
73
351
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
1.9
6.8
91
481
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.4
6.8
413
3158
SPAT1146
SPAT
Puncture of abscess or incision of skin
2.8
6.8
40
142
H02AB04
ATC
methylprednisolone; systemic
1.5
6.8
225
1536
JLE03
NOMESCO Finland
Allogenic total transplantation of pancreas with pancreaticoenterostomy
10.9
6.8
12
11
EBA10
NOMESCO Finland
Surgical removal of tooth
1.3
6.8
569
4568
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
1.7
6.7
138
838
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
1.8
6.7
100
549
E10
ICD-10 Finland
Type 1 diabetes mellitus
2.1
6.7
70
335
F60.3
ICD-10 Finland
Emotionally unstable personality disorder
2.4
6.7
54
229
C08CA01
ATC
amlodipine; oral
1.4
6.7
265
1879
EBA00
NOMESCO Finland
Extraction of tooth
1.2
6.7
1029
8882
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
1.7
6.7
122
716
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.8
6.7
115
664
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
2.4
6.7
54
230
N06AX03
ATC
mianserin; oral
2.2
6.7
67
314
G04BD04
ATC
oxybutynin; oral, transdermal
2.2
6.7
65
303
QAE50
NOMESCO Finland
Dermabrasion of superficial lesion of skin of head or neck
22.6
6.7
9
*
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.3
6.6
821
6916
F60.31
ICD-10 Finland
Emotionally unstable personality disorder, borderline condition
2.1
6.6
67
318
M01AH05
ATC
etoricoxib; oral
1.2
6.6
1198
10517
AA1AD
NOMESCO Finland
CT of head and brain
1.4
6.6
303
2210
SPAT1221
SPAT
Guidance concerning rehabilitation services and livelihood
2.3
6.6
54
233
BEF00
NOMESCO Finland
Continuous subcutaneous glucose monitoring
2.9
6.6
38
133
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.7
6.6
131
789
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.2
6.6
1512
13594
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.3
6.6
655
5372
R05
ICPC
Cough
1.3
6.5
584
4725
K03.64
ICD-10 Finland
Dental calculus supragingival
1.2
6.5
942
8075
N06AG02
ATC
moclobemide; oral
2.1
6.5
64
301
SFA40
NOMESCO Finland
Replacement of krone of tooth
1.4
6.5
293
2132
L72.0
ICD-10 Finland
Epidermal cyst
4.5
6.5
21
47
TLC00
NOMESCO Finland
Insertion of intrauterine device
1.5
6.4
193
1292
R01AD08
ATC
fluticasone; nasal
1.3
6.4
699
5792
H60.9
ICD-10 Finland
Otitis externa, unspecified
1.6
6.4
173
1126
A08.4
ICD-10 Finland
Viral intestinal infection, unspecified
1.6
6.4
164
1057
A02BA02
ATC
ranitidine; systemic
1.5
6.4
219
1505
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.5
6.4
229
1589
MA5AE
NOMESCO Finland
Morphology ultrasound screening, weeks 18+0 to 21+6 of gestation
0.6
6.4
117
1827
K50.8
ICD-10 Finland
Other Crohn disease
2.3
6.4
55
241
SPAT1380
SPAT
Postpartum check-up
0.7
6.4
311
4082
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.4
6.4
287
2083
C09AA02
ATC
enalapril; systemic
1.6
6.4
151
953
H26.2
ICD-10 Finland
Complicated cataract
4.3
6.4
22
52
QDH01
NOMESCO Finland
Excision of nail bed in toe
14.3
6.4
10
7
Z34.8
ICD-10 Finland
Supervision of other normal pregnancy
0.7
6.4
333
4324
KA1AE
NOMESCO Finland
Kidney ultrasound examination
2.6
6.4
42
161
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
3.6
6.4
26
72
R61.0
ICD-10 Finland
Localized hyperhidrosis
3.9
6.4
24
62
TDM10
NOMESCO Finland
Puncture of maxillary antrum
1.8
6.3
101
570
CKC15
NOMESCO Finland
Panretinal photocoagulation
4.9
6.3
19
39
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.4
6.3
260
1857
L65.9
ICD-10 Finland
Nonscarring hair loss, unspecified
6.5
6.3
15
23
N05AB03
ATC
perphenazine; systemic, rectal
2.0
6.3
76
387
N05AN01
ATC
lithium; oral
2.0
6.3
72
361
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
4.6
6.3
20
44
K65.0
ICD-10 Finland
Acute peritonitis
3.8
6.3
24
63
UJF30
NOMESCO Finland
Ileoscopy through colon
1.6
6.2
171
1119
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.4
6.2
298
2187
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
1.8
6.2
105
600
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.5
6.2
180
1192
QDH05
NOMESCO Finland
Correction of deformity of toe nail
7.0
6.2
14
20
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
1.9
6.2
82
434
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
1.6
6.2
166
1082
ZXC50
NOMESCO Finland
Cryotherapy
3.4
6.2
27
79
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.7
6.2
117
694
SPAT1254
SPAT
Administration of medicine
1.3
6.2
404
3123
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.7
6.2
122
733
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
1.8
6.2
108
626
WX290
NOMESCO Finland
Other blockade of nerve
1.2
6.1
1600
14520
QAA40
NOMESCO Finland
Laser therapy or photocoagulation of skin of head or neck
5.3
6.1
17
32
A10AE06
ATC
insulin degludec; parenteral
1.9
6.1
79
413
D07CA01
ATC
hydrocortisone and antibiotics; topical
1.4
6.1
320
2387
L84
ICD-10 Finland
Corns and callosities
2.4
6.1
50
214
XF400
NOMESCO Finland
ECG with 12 standard connections
1.5
6.1
232
1633
H03AA01
ATC
levothyroxine sodium; systemic
1.3
6.1
390
3006
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.6
6.1
154
991
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.7
6.1
109
636
F34.1
ICD-10 Finland
Dysthymia
1.8
6.1
104
601
D19
ICPC
Teeth/gum symptom/complaint
1.2
6.1
777
6558
SPAT1379
SPAT
Health check-up of pregnant person
0.8
6.1
394
4973
K51.5
ICD-10 Finland
Left sided colitis
1.9
6.0
81
432
EMB10
NOMESCO Finland
Tonsillectomy
1.4
6.0
271
1968
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
1.8
6.0
96
542
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
1.6
6.0
142
898
D86.8
ICD-10 Finland
Sarcoidosis of other and combined sites
5.2
6.0
17
33
J20
ICD-10 Finland
Acute bronchitis
1.5
6.0
182
1223

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: L12_ACNE_VULGARIS – Acne vulgaris

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).