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Other inflammatory liver diseases

DOID EFO Endpoint Browser PheWeb

K11_OTHINFLIV

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — K75
  • Hospital discharge: ICD-9 — 5720A
  • Hospital discharge: ICD-8 — 57300
  • Cause of death: ICD-10 — K75
  • Cause of death: ICD-9 — 5720A
  • Cause of death: ICD-8 — 57300

2 out of 7 registries used, show all original rules.

2552

4. Check minimum number of events

None

2552

5. Include endpoints

None

2552

6. Filter based on genotype QC (FinnGen only)

2552

Control definitions (FinnGen only)

Control exclude
K11_LIVER

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
K70-K77
Name in latin
Alii morbi inflammatorii hepatis

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 19596 10245 9148
Only index persons 16233 8849 7384
Unadjusted period prevalence (%)
Whole population 0.27 0.29 0.26
Only index persons 0.31 0.33 0.28
Median age at first event (years)
Whole population 52.11 54.22 49.73
Only index persons 50.76 52.78 48.34

-FinnGen-

Key figures

All Female Male
Number of individuals 2552 1462 1090
Unadjusted period prevalence (%) 0.49 0.50 0.48
Median age at first event (years) 51.01 50.75 51.35

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2326
Matched controls
23254
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
54.3
323.0
452
103
K75.9
ICD-10 Finland
Inflammatory liver disease, unspecified
+∞
323.0
1519
*
K75.0
ICD-10 Finland
Abscess of liver
+∞
287.6
270
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
9.6
284.0
640
884
K73.2
ICD-10 Finland
Chronic active hepatitis, not elsewhere classified
2726.3
268.9
255
*
K75.4
ICD-10 Finland
Autoimmune hepatitis
+∞
260.4
245
*
K76.9
ICD-10 Finland
Liver disease, unspecified
392.2
250.8
248
7
A05AA02
ATC
ursodeoxycholic acid; oral
48.1
210.1
257
60
57300
ICD-8 Finland
Other diseases of liver, Hepatitis NUD
+∞
207.4
196
*
L04AX01
ATC
azathioprine; systemic
10.6
176.2
363
400
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
5.0
164.4
617
1574
K75.2
ICD-10 Finland
Nonspecific reactive hepatitis
1363.8
133.7
129
*
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
32.9
131.2
174
57
K73.9
ICD-10 Finland
Chronic hepatitis, unspecified
1330.2
130.5
126
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.1
125.2
940
4167
K74.3
ICD-10 Finland
Primary biliary cirrhosis
+∞
125.1
119
*
K74.6
ICD-10 Finland
Other and unspecified cirrhosis of liver
+∞
111.3
106
*
R17
ICD-10 Finland
Hyperbilirubinaemia, with or without jaundice, not elsewhere classified
20.7
110.9
168
87
R74.0
ICD-10 Finland
Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]
21.4
108.2
162
81
A07EA06
ATC
budesonide; oral, local oral
8.9
106.7
239
296
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
4.1
105.3
464
1325
K83.0
ICD-10 Finland
Cholangitis
19.9
102.9
158
85
K70.3
ICD-10 Finland
Alcoholic cirrhosis of liver
848.0
84.1
82
*
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
16.6
80.8
132
84
JJ1LE
NOMESCO Finland
Ultrasound elastography of liver
37.6
78.9
101
28
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
9.8
78.0
163
177
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.4
73.0
885
4801
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.5
72.0
381
1238
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
9.0
71.9
158
187
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.3
70.1
958
5480
I85.9
ICD-10 Finland
Oesophageal varices without bleeding
74.1
69.6
79
11
H02AB06
ATC
prednisolone; systemic
2.2
69.1
1207
7706
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.2
68.7
1108
6824
R50.9
ICD-10 Finland
Fever, unspecified
3.0
67.3
450
1724
A02BC02
ATC
pantoprazole; systemic
2.2
64.8
1583
11550
K70.1
ICD-10 Finland
Alcoholic hepatitis
634.8
63.1
62
*
K72.0
ICD-10 Finland
Acute and subacute hepatic failure
+∞
62.8
60
*
TJJ00
NOMESCO Finland
Percutaneous needle biopsy of liver
131.5
60.1
64
5
N02AX02
ATC
tramadol; systemic, rectal
2.1
57.8
1063
6752
Z94.4
ICD-10 Finland
Liver transplant status
104.4
56.1
61
6
K75.3
ICD-10 Finland
Granulomatous hepatitis, not elsewhere classified
+∞
54.4
52
*
TPH04
NOMESCO Finland
Cathetrisation of vein
2.4
53.7
572
2824
B18.2
ICD-10 Finland
Chronic viral hepatitis C
14.0
53.5
93
69
R94.5
ICD-10 Finland
Abnormal results of liver function studies
13.8
52.7
92
69
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.5
52.6
467
2091
K72.9
ICD-10 Finland
Hepatic failure, unspecified
184.1
52.1
54
*
UJK02
NOMESCO Finland
ERCP
7.0
50.8
130
195
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
8.8
50.6
111
131
K73.0
ICD-10 Finland
Chronic persistent hepatitis, not elsewhere classified
+∞
49.1
47
*
UJF32
NOMESCO Finland
Coloscopy
2.1
48.8
673
3720
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.0
48.3
312
1149
K71.2
ICD-10 Finland
Toxic liver disease with acute hepatitis
+∞
48.1
46
*
K75.8
ICD-10 Finland
Other specified inflammatory liver diseases
+∞
47.0
45
*
L01BB02
ATC
mercaptopurine; oral
13.9
46.7
81
60
C03DA01
ATC
spironolactone; oral
3.0
46.5
298
1091
JJC00
NOMESCO Finland
Allogenic transplantation of liver
163.3
46.0
48
*
L04AA06
ATC
mycophenolic acid; systemic
8.1
43.2
100
129
A06AD11
ATC
lactulose; oral
2.5
41.2
369
1642
J01MA12
ATC
levofloxacin; systemic
2.2
40.4
474
2406
J01MA02
ATC
ciprofloxacin; systemic
1.9
40.2
914
6023
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
2.6
40.1
327
1380
JL5SB
NOMESCO Finland
Endoscopic retrograd cholangiopancreaticography
7.7
38.2
91
123
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
4.7
38.0
134
297
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
2.6
37.8
307
1290
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
21.6
37.5
55
26
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
12.7
37.3
67
54
B19.9
ICD-10 Finland
Unspecified viral hepatitis without hepatic coma
71.1
37.0
42
6
JJ9AE
NOMESCO Finland
Ultrasound examination of liver transplant
132.1
36.8
39
*
L04AD01
ATC
ciclosporin; systemic
7.1
36.6
92
135
XF400
NOMESCO Finland
ECG with 12 standard connections
2.2
36.0
426
2159
JN3AD
NOMESCO Finland
Abdominal CT examination
2.9
35.1
229
841
JKE02
NOMESCO Finland
Transduodenal endoscopic incision of common bile duct orifice
8.3
34.6
78
97
D97
ICPC
Liver disease NOS
25.8
34.5
48
19
JL5CG
NOMESCO Finland
Extensive MRI examinaiton of bile and pancreas ducts with high intesity magnet
13.0
34.4
61
48
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
3.2
34.4
196
658
UJF30
NOMESCO Finland
Ileoscopy through colon
2.6
33.6
269
1116
C03CA01
ATC
furosemide; systemic
1.9
33.6
603
3606
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
9.2
33.1
70
78
127
Kela drug reimbursment
Transplant complication
8.2
33.1
75
94
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.3
32.7
178
577
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
2.9
32.7
211
769
K51.5
ICD-10 Finland
Left sided colitis
5.2
32.3
103
205
ZX120
NOMESCO Finland
Intravenous
2.6
32.0
253
1041
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.2
31.7
368
1843
ZXE00
NOMESCO Finland
One hour or less
1.7
30.0
898
6285
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
12.0
29.9
55
47
P01AB01
ATC
metronidazole; oral, rectal
1.7
29.6
909
6402
A07EC02
ATC
mesalazine; oral, rectal
3.2
29.2
165
549
H02AB07
ATC
prednisone; oral
2.1
28.9
355
1815
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
2.8
28.8
201
769
Z01.8
ICD-10 Finland
Other specified special examinations
1.9
28.7
515
3053
K76.89
ICD-10 Finland
Other specified diseases of liver
151.9
28.7
30
*
ZXD05
NOMESCO Finland
Urgent procedure
1.7
28.5
708
4671
K70.9
ICD-10 Finland
Alcoholic liver disease, unspecified
+∞
28.2
27
*
WX408
NOMESCO Finland
General anesthesy, balanced
1.8
28.0
626
3989
I85.0
ICD-10 Finland
Oesophageal varices with bleeding
284.8
27.8
28
*
R18
ICD-10 Finland
Ascites
7.4
27.5
66
91
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.9
27.5
181
666
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
2.6
27.5
210
845
K83.1
ICD-10 Finland
Obstruction of bile duct
7.7
27.3
64
85
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.0
27.2
387
2098
K74.0
ICD-10 Finland
Hepatic fibrosis
+∞
27.1
26
*
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
3.3
26.9
139
434
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
4.1
26.4
105
263
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
4.2
25.7
101
250
JJ5AT
NOMESCO Finland
NA
94.5
25.7
28
*
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
7.1
25.2
62
89
A09AA02
ATC
multienzymes (lipase, protease etc.)
5.5
25.1
76
143
Z2221
NOMESCO Finland
Medical doctor
1.7
25.0
631
4145
A02BC03
ATC
lansoprazole; oral
1.7
25.0
657
4372
A02BC01
ATC
omeprazole; systemic
1.7
25.0
615
4015
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.0
24.8
371
2046
B15.9
ICD-10 Finland
Hepatitis A without hepatic coma
91.1
24.7
27
*
N02AA05
ATC
oxycodone; systemic
2.1
24.6
324
1697
JN4BD
NOMESCO Finland
Extensive body CT
2.2
24.1
261
1255
103
Kela drug reimbursment
Diabetes, insulin-treated
1.7
23.9
565
3631
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.1
23.7
298
1531
A41.9
ICD-10 Finland
Sepsis, unspecified
3.7
23.5
105
292
K80.5
ICD-10 Finland
Calculus of bile duct without cholangitis or cholecystitis
4.1
23.3
93
234
K80.0
ICD-10 Finland
Calculus of gallbladder with acute cholecystitis
3.2
23.0
125
405
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.8
23.0
485
3007
K92.0
ICD-10 Finland
Haematemesis
5.2
22.9
72
142
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.8
22.9
484
3005
A10AE04
ATC
insulin glargine; parenteral
2.3
22.6
225
1042
SPAT1262
SPAT
Handing over of treatment supplies
1.8
22.3
407
2406
JCA22
NOMESCO Finland
Endoscopic ligature of oesophageal varices
52.5
22.1
26
5
J01FF01
ATC
clindamycin; systemic
1.7
21.9
598
3991
K70.0
ICD-10 Finland
Alcoholic fatty liver
63.1
21.9
25
*
B17.1
ICD-10 Finland
Acute hepatitis C
39.0
21.7
27
7
K76.80
ICD-10 Finland
Hepatic cyst
80.9
21.7
24
*
Z3231
NOMESCO Finland
Registered nurse
1.7
21.7
600
4023
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.8
21.4
465
2902
WX892
NOMESCO Finland
Monitored bed care
2.4
21.4
185
795
WX002
NOMESCO Finland
Sedation and analgesia
1.8
21.3
436
2669
D37.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Liver, gallbladder and bile ducts
6.2
20.8
56
92
C07AA05
ATC
propranolol; systemic
1.8
20.8
431
2649
A02BC05
ATC
esomeprazole; systemic
1.5
20.5
879
6564
TPH07
NOMESCO Finland
Cathetrisation of artery
2.2
20.4
231
1132
ZXE10
NOMESCO Finland
More than one and less than three hours
1.6
20.3
791
5768
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.1
20.3
250
1269
ZXD10
NOMESCO Finland
Scheduled procedure
1.6
20.3
833
6154
JJ1AT
NOMESCO Finland
Puncture of lesion of liver with ultrasound guidance
32.8
20.2
26
8
Z2446
NOMESCO Finland
Social worker
2.6
20.1
156
631
T90
ICPC
Diabetes non-insulin dependent
1.7
20.0
484
3110
XF600
NOMESCO Finland
Bloodpressure measurement
2.5
20.0
159
656
K71.9
ICD-10 Finland
Toxic liver disease, unspecified
+∞
19.8
19
*
K72.1
ICD-10 Finland
Chronic hepatic failure
+∞
19.8
19
*
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.7
19.6
508
3328
K85.9
ICD-10 Finland
Acute pancreatitis, unspecified
5.1
19.6
62
124
B16.9
ICD-10 Finland
Acute hepatitis B without delta-agent and without hepatic coma
105.9
19.6
21
*
B17.8
ICD-10 Finland
Other specified acute viral hepatitis
201.6
19.6
20
*
K70.4
ICD-10 Finland
Alcoholic hepatic failure
201.6
19.6
20
*
N05CF01
ATC
zopiclone; oral
1.6
19.2
694
4959
K83.9
ICD-10 Finland
Disease of biliary tract, unspecified
18.3
19.1
29
16
N05CD07
ATC
temazepam; oral
1.9
19.0
285
1563
K86.1
ICD-10 Finland
Other chronic pancreatitis
7.8
18.8
43
56
57309
ICD-8 Finland
Other diseases of liver, Unspecified
+∞
18.8
18
*
JJ3AT
NOMESCO Finland
Cytology of liver with ultrasound guidance
23.9
18.6
26
11
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.5
18.0
860
6529
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.9
18.0
270
1481
J01DB01
ATC
cefalexin; oral
1.6
18.0
1809
16089
Z3226
NOMESCO Finland
Physiotherapist
1.7
17.9
404
2533
C10AC01
ATC
colestyramine; oral
3.7
17.9
80
224
N06AB04
ATC
citalopram; systemic
1.7
17.9
462
3014
N05BA01
ATC
diazepam; systemic, rectal
1.9
17.8
298
1696
JJA20
NOMESCO Finland
Open biopsy of liver
20.2
17.7
26
13
K75.1
ICD-10 Finland
Phlebitis of portal vein
+∞
17.7
17
*
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.8
17.6
118
441
K81.0
ICD-10 Finland
Acute cholecystitis
4.7
17.4
59
128
E13.9
ICD-10 Finland
Other specified diabetes mellitus, without complications
6.7
17.4
44
67
JKE18
NOMESCO Finland
Endoscopic internal drainage of bile duct
7.1
17.3
42
60
SPAT1255
SPAT
Intravenous administration of medicine
2.4
17.3
157
693
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
4.8
17.3
57
120
D64.9
ICD-10 Finland
Anaemia, unspecified
2.1
17.2
208
1046
R4110
NOMESCO Finland
Physiotherapy
1.6
17.2
552
3809
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.8
17.2
113
417
N05AH04
ATC
quetiapine; oral
1.8
17.1
345
2091
JN4AD
NOMESCO Finland
Body CT examination
2.2
17.1
173
803
K85
ICD-10 Finland
Acute pancreatitis
5.0
16.9
54
110
R11
ICD-10 Finland
Nausea and vomiting
2.2
16.7
180
861
C07AB07
ATC
bisoprolol; oral
1.5
16.7
943
7381
JX1XE
NOMESCO Finland
Other ultrasound examinaton of alimentary organs
35.3
16.7
21
6
A07AA11
ATC
rifaximin; oral
90.7
16.6
18
*
JJ4AT
NOMESCO Finland
Catherisation of liver lesion with ultrasound guidance
171.1
16.5
17
*
K50.8
ICD-10 Finland
Other Crohn disease
4.9
16.5
54
113
JA2AT
NOMESCO Finland
Abdominal puncture with ultrasound guidance
8.3
16.5
36
44
UJK12
NOMESCO Finland
Peroral cholangioscopy
18.0
16.5
25
14
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.5
16.4
602
4288
A41.8
ICD-10 Finland
Other specified sepsis
4.8
16.4
54
114
AA1AD
NOMESCO Finland
CT of head and brain
1.6
16.3
473
3176
JA3BT
NOMESCO Finland
Cathetrisation of abdominal cavity with X-ray guidance
14.4
16.3
27
19
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.1
16.2
88
287
3AC01
NOMESCO Finland
NA
6.9
16.2
40
59
JN1BG
NOMESCO Finland
MRI examination of upper part of abodmen with high intensity magnet
6.6
16.1
41
63
WX402
NOMESCO Finland
General anaesthesia
1.7
16.1
354
2201
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
2.7
16.0
114
440
K80.3
ICD-10 Finland
Calculus of bile duct with cholangitis
6.8
16.0
40
60
N17.9
ICD-10 Finland
Acute renal failure, unspecified
3.1
16.0
89
296
TK800
NOMESCO Finland
Hemodialysis
3.9
15.9
65
169
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
3.5
15.9
75
220
F10.24
ICD-10 Finland
Alcohol depence active use
5.4
15.9
47
88
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.9
15.7
254
1428
N07BB01
ATC
disulfiram; oral
2.7
15.6
109
418
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
2.6
15.6
115
454
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
3.7
15.6
69
193
R4190
NOMESCO Finland
Nutritional therapy
3.1
15.5
85
280
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.1
15.4
178
880
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.3
15.3
138
608
ZXE20
NOMESCO Finland
More than three and less than five hours
1.8
15.2
293
1749
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
3.7
15.2
66
182
F10.20
ICD-10 Finland
Alcohol dependence currently independent
3.9
15.1
62
163
JKA20
NOMESCO Finland
Cholecystectomy
3.2
14.9
78
249
N03AE01
ATC
clonazepam; systemic
2.3
14.8
137
611
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.8
14.7
289
1732
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.5
14.6
689
5159
K73.89
ICD-10 Finland
Other long-term hepatitis, not classified differently
+∞
14.6
14
*
5720A
ICD-9 Finland
Liver abscess and sequelae of chronic liver disease, Abscess of liver
+∞
14.6
14
*
UJD02
NOMESCO Finland
Gastroscopy
2.5
14.5
116
481
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.0
14.5
189
982
H03AA01
ATC
levothyroxine sodium; systemic
1.6
14.5
488
3389
P01BA02
ATC
hydroxychloroquine; oral
2.0
14.4
185
954
R53
ICD-10 Finland
Malaise and fatigue
1.6
14.3
412
2751
K51.8
ICD-10 Finland
Other ulcerative colitis
5.0
14.3
45
91
T36
ICD-10 Finland
Poisoning by systemic antibiotics
2.6
14.3
102
398
B01AB05
ATC
enoxaparin; parenteral
1.5
14.2
615
4519
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.2
14.1
152
728
R56.8
ICD-10 Finland
Other and unspecified convulsions
2.5
14.0
113
471
K86.00
ICD-10 Finland
Acute pancreatitis caused by alcohol
5.4
13.9
41
77
WX110
NOMESCO Finland
Local anesthesy
1.4
13.7
1450
12575
JN1BD
NOMESCO Finland
Extensive CT examination of upper part of abdomen
7.4
13.7
32
44
K86.08
ICD-10 Finland
Alcohol-induced chronic pancreatitis
12.1
13.6
24
20
K71.0
ICD-10 Finland
Toxic liver disease with cholestasis
+∞
13.6
13
*
K74.5
ICD-10 Finland
Biliary cirrhosis, unspecified
+∞
13.6
13
*
ZXE40
NOMESCO Finland
More than seven and less than nine hours
3.4
13.5
65
195
K50.9
ICD-10 Finland
Crohn disease, unspecified
4.7
13.5
45
97
F10.25
ICD-10 Finland
Alcohol dependence continuous use
4.2
13.4
50
121
N05BA04
ATC
oxazepam; oral
1.5
13.4
509
3628
F15.1
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, harmful use
13.9
13.2
22
16
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
4.5
13.2
46
104
ZXE30
NOMESCO Finland
More than five and less than seven hours
2.4
13.1
116
507
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
4.4
13.1
46
105
JKE12
NOMESCO Finland
Endoscopic extraction of calculus from bile duct
5.0
13.1
41
83
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.0
13.0
169
874
K86.3
ICD-10 Finland
Pseudocyst of pancreas
8.3
13.0
28
34
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.6
13.0
341
2220
K50.1
ICD-10 Finland
Crohn disease of large intestine
4.9
12.9
41
84
R10.0
ICD-10 Finland
Acute abdomen
2.8
12.9
81
293
Z72.2
ICD-10 Finland
Drug use
11.6
12.8
23
20
C08CA01
ATC
amlodipine; oral
1.4
12.8
677
5164
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.7
12.8
266
1621
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
12.7
1056
8733
N03AX16
ATC
pregabalin; oral
1.5
12.7
485
3456
N03AX12
ATC
gabapentin; oral
1.6
12.6
320
2062
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.6
12.5
345
2275
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.4
12.3
108
472
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.2
12.3
126
592
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.1
12.3
144
717
WW500
NOMESCO Finland
Blood transfusion
2.6
12.2
89
352
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.0
12.1
158
820
L04AA01
ATC
[U] ciclosporin; systemic
4.1
12.1
46
114
F19.1
ICD-10 Finland
Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances, harmful use
8.7
12.0
25
29
F15.2
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, dependence syndrome
10.1
12.0
23
23
A02BA02
ATC
ranitidine; systemic
1.5
12.0
390
2676
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.8
12.0
212
1230
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.7
11.8
246
1496
H02AB09
ATC
hydrocortisone; systemic
3.1
11.8
64
211
TKC20
NOMESCO Finland
Catheterisation of bladder
2.1
11.8
141
708
K29.3
ICD-10 Finland
Chronic superficial gastritis
2.8
11.8
74
268
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
4.1
11.8
45
112
UJF92
NOMESCO Finland
Capsular endoscopy
3.2
11.7
60
190
WX302
NOMESCO Finland
Thoracal epidural anesthesy
2.2
11.6
118
552
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
2.6
11.6
81
314
N06AX11
ATC
mirtazapine; oral
1.4
11.6
639
4893
JK3BT
NOMESCO Finland
Catherisation of bile duct with X-ray guidance
10.1
11.5
22
22
57308
ICD-8 Finland
Other diseases of liver, Alii definiti
+∞
11.5
11
*
K73.8
ICD-10 Finland
Other chronic hepatitis, not elsewhere classified
+∞
11.5
11
*
5714B
ICD-9 Finland
Chronic liver disease and cirrhosis, Chronic hepatitis[HEPATITIS CHRONICA ACTIVA (HBSAG-)]
120.6
11.4
12
*
K51.1
ICD-10 Finland
Ulcerative (chronic) ileocolitis
5.1
11.4
35
70
K50.0
ICD-10 Finland
Crohn disease of small intestine
3.8
11.3
47
126
L04AA05
ATC
[U] tacrolimus; systemic
35.2
11.3
14
*
C22.0
ICD-10 Finland
Malignant neoplasm: Liver cell carcinoma
8.9
11.2
23
26
K80.4
ICD-10 Finland
Calculus of bile duct with cholecystitis
5.0
11.2
35
71
K65.0
ICD-10 Finland
Acute peritonitis
5.1
11.2
34
67
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.2
11.2
109
502
K29.6
ICD-10 Finland
Other gastritis
5.7
11.2
31
55
K85.0
ICD-10 Finland
Idiopathic acute pancreatitis
6.8
11.1
27
40
K73.80
ICD-10 Finland
Non-alcoholic fatty liver (NASH, Non Alcoholic Steatohepatitis)
20.1
11.1
16
8
F10.40
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without seizures
5.2
11.0
33
64
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.4
11.0
524
3896
WX872
NOMESCO Finland
Intensive care
2.2
10.9
106
486
P15
ICPC
Chronic alcohol abuse
3.0
10.9
62
210
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
1.9
10.9
156
840
JKE32
NOMESCO Finland
Endoscopic dilatation of bile duct
12.0
10.8
19
16
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
2.6
10.8
77
303
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.7
10.8
215
1295
JLC30
NOMESCO Finland
Pancreatoduodenectomy
7.2
10.7
25
35
JN1CD
NOMESCO Finland
Very extensive CT examination of upper part of abdomen
5.2
10.7
32
62
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.9
10.7
163
897
N30.0
ICD-10 Finland
Acute cystitis
1.6
10.7
267
1712
JN4CD
NOMESCO Finland
Very extensive body CT
2.4
10.6
89
381
F19.20
ICD-10 Finland
Addiction relationship caused by several drugs in combination and by other psychoactive substances currently independent
8.5
10.5
22
26
A10BA02
ATC
metformin; oral
1.4
10.5
510
3803
326
Kela drug reimbursment
Adalimumab, golimumab, infliximab and ustekinumab (intestinal diseases)
6.6
10.5
26
40
L28
ICPC
Limited function/disability (L)
1.6
10.4
284
1863
K77.0*B25.1
ICD-10 Finland
Cytomegaloviral hepatitis
+∞
10.4
10
*
5719X
ICD-9 Finland
Chronic liver disease and cirrhosis, Unspecified chronic liver disease without mention of alcohol
+∞
10.4
10
*
K76.7
ICD-10 Finland
Hepatorenal syndrome
+∞
10.4
10
*
K86.01
ICD-10 Finland
Late effects of pancreatitis caused by alcohol
16.1
10.3
16
10
K83.8
ICD-10 Finland
Other specified diseases of biliary tract
12.1
10.3
18
15
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.6
10.3
263
1696
N05BA12
ATC
alprazolam; oral
1.7
10.3
205
1232
A03FA01
ATC
metoclopramide; systemic, rectal
1.5
10.2
408
2918
K81.9
ICD-10 Finland
Cholecystitis, unspecified
4.5
10.2
35
79
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
3.2
10.2
52
166
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.8
10.1
185
1080
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.2
10.1
104
492
JAH00
NOMESCO Finland
Laparotomy
2.7
10.1
65
241
F13.22
ICD-10 Finland
Addiction relationship caused by sedatives and hypnotics currently independent but uses substitute intermittent medication
7.9
10.1
22
28
JKE22
NOMESCO Finland
Endoscopic extraction of foreign body from bile duct
7.9
10.1
22
28
F10.49
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without information about seizures
7.9
10.1
22
28
J01MA14
ATC
moxifloxacin; systemic
1.8
10.1
179
1038
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
2.1
10.0
108
521
E14.9
ICD-10 Finland
Unspecified diabetes mellitus, without complications
3.6
10.0
44
125
JJA21
NOMESCO Finland
Laparoscopic biopsy of liver
10.1
10.0
19
19
M04AA01
ATC
allopurinol; systemic
1.7
10.0
230
1440
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
2.3
10.0
87
381
S97
ICPC
Chronic ulcer skin
2.2
9.9
104
493
EBA15
NOMESCO Finland
Extraction of large number of teeth
2.4
9.9
80
335
K30
ICD-10 Finland
Functional dyspepsia
1.7
9.9
218
1353
K80.1
ICD-10 Finland
Calculus of gallbladder with other cholecystitis
2.9
9.8
59
210
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.6
9.8
276
1823
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
2.7
9.8
64
240
ZXE90
NOMESCO Finland
More than 22 hours
5.4
9.8
28
52
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.9
9.8
150
830
F11.22
ICD-10 Finland
Addiction-induced dependence is currently independent but uses substitute intermittent medication
8.8
9.8
20
23
E0000UV
ATC
NA
1.4
9.7
770
6234
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.0
9.7
131
689
O99.6
ICD-10 Finland
Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
7.4
9.7
22
30
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
5.1
9.7
29
57
JN1DM
NOMESCO Finland
Upper part of abdomen very extensive MRI examination with 3 Tesla magnet
55.2
9.6
11
*
R06.0
ICD-10 Finland
Dyspnoea
1.4
9.6
461
3424
SPAT1263
SPAT
Sampling
1.3
9.5
841
6919
C24.9
ICD-10 Finland
Malignant neoplasm: Biliary tract, unspecified
15.1
9.5
15
10
J01DA01
ATC
[U] cefalexin; systemic
1.3
9.5
1303
11437
D02
ICPC
Abdominal pain epigastric
2.0
9.5
115
582
M79.6
ICD-10 Finland
Pain in limb
1.4
9.5
697
5574
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
2.4
9.5
80
343
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
3.5
9.5
43
126
UJF02
NOMESCO Finland
Peroral enteroscopy
6.2
9.4
24
39
F19.25
ICD-10 Finland
Addiction caused by several drugs in combination and by other psychoactive substances continuously used
12.4
9.4
16
13
TPX10
NOMESCO Finland
Implantation of vascular injection port
2.6
9.3
64
247
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
2.0
9.3
122
636
E87.6
ICD-10 Finland
Hypokalaemia
2.7
9.3
61
230
N05AF03
ATC
chlorprothixene; systemic
2.7
9.2
62
236
A11CC03
ATC
alfacalcidol; systemic
3.0
9.2
50
168
TJK01
NOMESCO Finland
Laparoscopic cholangiography
4.8
9.1
29
61
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
2.7
9.1
59
220
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
6.3
9.1
23
37
F10.26
ICD-10 Finland
Alcohol dependence periodic alcoholism
3.5
9.1
41
120
XW000
NOMESCO Finland
Bone marrow biopsy
2.3
9.1
83
371
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.4
9.0
520
3986
K80.8
ICD-10 Finland
Other cholelithiasis
3.6
9.0
39
110
XX4AT
NOMESCO Finland
Other canalization with ultrasound guidance
9.1
9.0
18
20
JK3NB
NOMESCO Finland
Percutaneous transhepatic cholangiography
10.1
9.0
17
17
K02.1
ICD-10 Finland
Caries of dentine
1.3
9.0
1147
9927
B99
ICD-10 Finland
Other and unspecified infectious diseases
3.1
9.0
48
159
F10.39
ICD-10 Finland
Withdrawal symptoms caused by alcohol UNS
4.9
9.0
28
58
M05BA04
ATC
alendronic acid; oral
1.8
8.9
155
891
A28
ICPC
Limited function/disability NOS
1.6
8.9
250
1649
E13.8
ICD-10 Finland
Other specified diabetes mellitus, with unspecified complications
24.1
8.9
12
5
F19.29
ICD-10 Finland
Addiction caused by several drugs in combination and by other psychoactive substances UNS
8.0
8.8
19
24
B01AA03
ATC
warfarin; systemic
1.5
8.7
344
2450
A07AA09
ATC
vancomycin; oral
4.0
8.7
33
83
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.4
8.7
556
4334
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
1.7
8.7
184
1125
A10AB04
ATC
insulin lispro; parenteral (insulins and analog. for injection, fast-acting)
2.4
8.7
70
295
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.4
8.7
398
2920
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.7
8.7
172
1033
K57.9
ICD-10 Finland
Diverticular disease of intestine, part unspecified, without perforation or abscess
2.8
8.7
53
192
D13
ICPC
Jaundice
50.2
8.7
10
*
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
7.7
8.6
19
25
ZXA00
NOMESCO Finland
Right side
1.4
8.6
508
3905
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.7
8.6
188
1162
G31.2
ICD-10 Finland
Degeneration of nervous system due to alcohol
6.2
8.6
22
36
B27.0
ICD-10 Finland
Gammaherpesviral mononucleosis
6.2
8.6
22
36
P16
ICPC
Acute alcohol abuse
3.4
8.6
40
120
A10AE05
ATC
insulin detemir; parenteral
2.0
8.6
110
569
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
1.9
8.5
130
720
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.6
8.5
220
1422
P19
ICPC
Drug abuse
4.9
8.5
26
53
PC2DE
NOMESCO Finland
Ultrasound examination of liver vasculature with Doppler method
20.1
8.5
12
6
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
2.7
8.5
54
200
J45.9
ICD-10 Finland
Asthma, unspecified
1.5
8.4
331
2356
R03AC02
ATC
salbutamol; inhalant
1.3
8.4
1034
8871
R93.2
ICD-10 Finland
Abnormal findings on diagnostic imaging of liver and biliary tract
7.4
8.4
19
26
I10
ICD-10 Finland
Essential (primary) hypertension
1.3
8.4
1100
9520
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
1.8
8.4
131
731
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
2.2
8.4
86
406
JKE25
NOMESCO Finland
Endoscopic external drainage of bile duct
12.8
8.4
14
11
M81.9
ICD-10 Finland
Osteoporosis, unspecified
2.2
8.4
79
361
K70.2
ICD-10 Finland
Alcoholic fibrosis and sclerosis of liver
+∞
8.3
8
*
5714X
ICD-9 Finland
Chronic liver disease and cirrhosis, Chronic hepatitis[HEPATITIS CHRONICA ALIA SEU NUD]
+∞
8.3
8
*
M25.5
ICD-10 Finland
Pain in joint
1.4
8.3
557
4371
J01EA01
ATC
trimethoprim; systemic
1.4
8.3
465
3544
D01
ICPC
Abdominal pain/cramps general
1.6
8.3
196
1239
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.4
8.3
413
3079
R60.0
ICD-10 Finland
Localized oedema
1.6
8.3
196
1240
N06AX16
ATC
venlafaxine; oral
1.5
8.3
265
1807
C22.9
ICD-10 Finland
Malignant neoplasm: Liver, unspecified
9.5
8.3
16
17
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.7
8.2
163
980
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.4
8.2
584
4624
ZXA10
NOMESCO Finland
Bilateral
1.5
8.2
344
2479
JK3NT
NOMESCO Finland
Percutaneous transhepatic dilatation of bileducts
14.5
8.2
13
9
R06AE07
ATC
cetirizine; oral
1.3
8.2
861
7225
A40.8
ICD-10 Finland
Other streptococcal sepsis
4.9
8.2
25
51
SPAT1254
SPAT
Administration of medicine
1.5
8.2
258
1750
R51.80
ICD-10 Finland
Headache
1.5
8.2
274
1887
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
2.1
8.1
94
468
RS220
NOMESCO Finland
NA
4.0
8.1
31
79
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
1.7
8.1
175
1077
J01FA06
ATC
roxithromycin; oral
1.3
8.1
789
6549
B18.1
ICD-10 Finland
Chronic viral hepatitis B without delta-agent
17.2
8.1
12
7
M13.9
ICD-10 Finland
Arthritis, unspecified
1.8
8.1
137
786
C09AA05
ATC
ramipril; oral
1.4
8.1
438
3318
H02AB04
ATC
methylprednisolone; systemic
1.5
8.1
275
1898
E66.01
ICD-10 Finland
Obesity due to excess calories
1.7
8.1
149
876
JKD20
NOMESCO Finland
Anastomosis of bile duct to jejunum
22.1
8.0
11
5
N05CF02
ATC
zolpidem; oral
1.4
8.0
344
2495
L04AB04
ATC
adalimumab; parenteral
3.0
8.0
44
150
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
2.0
8.0
101
521
N06AB05
ATC
paroxetine; oral
1.8
7.9
122
678
XX1AT
NOMESCO Finland
Other puncture with ultrasound guidance
3.7
7.8
32
87
S18
ICPC
Laceration/cut
1.3
7.8
794
6618
K90.3
ICD-10 Finland
Pancreatic steatorrhoea
5.7
7.8
21
37
J02AC01
ATC
fluconazole; systemic
1.3
7.8
776
6452
D86.9
ICD-10 Finland
Sarcoidosis, unspecified
4.7
7.8
25
54
JN1CM
NOMESCO Finland
Upper part of abdomen extensive MRI examination with 3 Tesla magnet
10.8
7.8
14
13
B03BA03
ATC
hydroxocobalamin; parenteral
1.9
7.8
102
536
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
2.5
7.7
57
230
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
7.7
821
6888
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
3.6
7.6
32
89
N06AB03
ATC
fluoxetine; oral
1.5
7.6
243
1653
N05BA02
ATC
chlordiazepoxide; systemic
2.7
7.6
50
190
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
1.7
7.6
142
840
SPAT1309
SPAT
Guidance related to psychoactive substances / risk behaviour
2.5
7.6
56
225
T89
ICPC
Diabetes insulin dependent
2.2
7.6
78
369
A04AA01
ATC
ondansetron; systemic, rectal
1.8
7.6
129
741
G73.7*M35.0
ICD-10 Finland
Myopathy in sicca syndrome [Sjögren]
25.1
7.6
10
*
K90.0
ICD-10 Finland
Coeliac disease
2.4
7.6
62
264
N06AB10
ATC
escitalopram; oral
1.4
7.6
380
2837
A46
ICD-10 Finland
Erysipelas
1.5
7.5
252
1735
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
3.1
7.5
39
128
R42
ICD-10 Finland
Dizziness and giddiness
1.4
7.5
396
2977
K86.9
ICD-10 Finland
Disease of pancreas, unspecified
7.1
7.5
17
24
N05AB01
ATC
dixyrazine; systemic
3.7
7.4
30
81
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
2.1
7.4
84
416
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
1.8
7.3
116
650
S42.2
ICD-10 Finland
Fracture of upper end of humerus
2.0
7.3
86
433
K86.8
ICD-10 Finland
Other specified diseases of pancreas
8.4
7.3
15
18
WZA90
NOMESCO Finland
Other doctors statement
1.4
7.3
437
3359
K92.1
ICD-10 Finland
Melaena
1.9
7.3
96
504
K73.1
ICD-10 Finland
Chronic lobular hepatitis, not elsewhere classified
+∞
7.3
7
*
D80.1
ICD-10 Finland
Nonfamilial hypogammaglobulinaemia
10.9
7.3
13
12
JLW98
NOMESCO Finland
Other transluminal endoscopic operation on pancreas
10.9
7.3
13
12
F05.9
ICD-10 Finland
Delirium, unspecified
3.0
7.3
38
126
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
2.2
7.2
66
298
E83.1
ICD-10 Finland
Disorders of iron metabolism
5.8
7.2
19
33
NF1AA
NOMESCO Finland
Hip X-ray examination
1.7
7.2
151
923
D86.0
ICD-10 Finland
Sarcoidosis of lung
3.6
7.2
30
84
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
2.8
7.1
43
156
07009
ICD-8 Finland
Infectious hepatitis, Unspecified
20.1
7.1
10
5
SPAT1249
SPAT
Treatment-related counselling outside office
1.3
7.1
766
6419
M05BA07
ATC
risedronic acid; oral
2.2
7.1
66
302
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
3.4
7.1
32
95
A03
ICPC
Fever
1.5
7.1
283
2021
A10BH01
ATC
sitagliptin; oral
1.6
7.1
168
1063
WX882
NOMESCO Finland
High dependency care
2.4
7.1
54
224
4AA12
NOMESCO Finland
NA
12.1
7.1
12
10
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.4
7.1
391
2964
M35.1
ICD-10 Finland
Other overlap syndromes
5.3
7.1
20
38
K85.2
ICD-10 Finland
Alcohol-induced acute pancreatitis
6.0
7.1
18
30
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
2.2
7.1
68
316
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.0
7.1
90
467
Z94.0
ICD-10 Finland
Kidney transplant status
3.9
7.1
27
70
ZY010
NOMESCO Finland
Hospital outpatient
2.0
7.1
86
440
UGC12
NOMESCO Finland
Flexible bronchoscopy
1.7
7.0
133
791
E66.8
ICD-10 Finland
Other obesity
1.9
7.0
98
527
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
2.1
7.0
72
343
XJD02
NOMESCO Finland
Peroral endoscopic ultrasonography
4.7
7.0
22
47
F10.09
ICD-10 Finland
Alcohol intoxication UNS
2.8
7.0
42
152
RD210
NOMESCO Finland
NA
2.8
7.0
42
152
R74.8
ICD-10 Finland
Abnormal levels of other serum enzymes
1.9
7.0
92
485
B07.9
ICD-10 Finland
Verruca simplex
2.2
7.0
67
311
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
2.3
7.0
61
269
WX419
NOMESCO Finland
Other general anesthesy
3.6
7.0
29
81
A10AD01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)
2.9
7.0
40
139
ZXA05
NOMESCO Finland
Left side
1.3
6.9
468
3666
JFB00
NOMESCO Finland
Partial resection of small intestine
3.2
6.9
34
108
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
2.1
6.9
78
387
A10AD05
ATC
insulin aspart; parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)
2.9
6.9
38
131
F11.1
ICD-10 Finland
Mental and behavioural disorders due to use of opioids, harmful use
13.8
6.9
11
8
N17.8
ICD-10 Finland
Other acute renal failure
3.9
6.9
26
67
X59
ICD-10 Finland
Exposure to unspecified factor
1.4
6.9
338
2512
R04.0
ICD-10 Finland
Epistaxis
1.8
6.8
119
690
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.5
6.8
252
1772
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
1.9
6.8
100
548
J01CA04
ATC
amoxicillin; systemic
1.3
6.8
1688
15652
J01CA08
ATC
pivmecillinam; oral
1.3
6.8
732
6128
SPAT1247
SPAT
Outpatient detoxication and monitoring
6.1
6.8
17
28
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
6.7
941
8133
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
1.9
6.7
99
544
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
1.8
6.7
112
641
F19.00
ICD-10 Finland
Intoxication caused by several drugs in combination or by other psychoactive substances uncomplicated
22.6
6.7
9
*
R60.9
ICD-10 Finland
Oedema, unspecified
1.9
6.7
89
471
X58
ICD-10 Finland
Exposure to other specified factors
1.5
6.7
247
1735
JF1CG
NOMESCO Finland
Extensive MRI of small bowel
4.4
6.6
22
50
TQW80
NOMESCO Finland
Local dermatologic skincare
2.4
6.6
53
223
R74.9
ICD-10 Finland
Abnormal level of unspecified serum enzyme
5.2
6.6
19
37
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.3
6.6
1039
9104
ZXX05
NOMESCO Finland
Extent of procedure, 5 units
7.8
6.6
14
18
F60.9
ICD-10 Finland
Personality disorder, unspecified
3.4
6.6
29
85
N18.8
ICD-10 Finland
Other chronic renal failure
2.4
6.6
51
214
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.4
6.6
324
2408
D07AC01
ATC
betamethasone; topical
1.3
6.6
647
5345
R07.3
ICD-10 Finland
Other chest pain
1.6
6.6
172
1119
Y83.9
ICD-10 Finland
Surgical procedure, unspecified as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.2
6.5
61
279
JK4ZT
NOMESCO Finland
Percutaneous transhepatic implantation of bile duct prothesis
10.0
6.5
12
12
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
2.1
6.5
71
348
ZX108
NOMESCO Finland
Inhalation
4.8
6.5
20
42
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
1.7
6.5
116
678
R4120
NOMESCO Finland
Occupational therapy
1.7
6.5
116
679
K57.0
ICD-10 Finland
Diverticular disease of small intestine with perforation and abscess
5.0
6.5
19
38
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
1.7
6.5
131
794
M10.9
ICD-10 Finland
Gout, unspecified
1.8
6.4
110
635
B17.2
ICD-10 Finland
Acute hepatitis E
70.0
6.4
7
*
J06BA01
ATC
immunoglobulins, normal human, for extravascular adm.; systemic
14.3
6.4
10
7
M07.4*K50.9
ICD-10 Finland
Arthropathy in Crohn's disease [regional enteritis]
14.3
6.4
10
7
K07
ICPC
Swollen ankles/oedema
2.0
6.4
76
385
S22.3
ICD-10 Finland
Fracture of rib
1.8
6.3
111
646
WW200
NOMESCO Finland
Immunization
2.3
6.3
55
246
A01AB09
ATC
miconazole; local oral
1.6
6.3
160
1034
F19.2
ICD-10 Finland
Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances, dependence syndrome
18.1
6.3
9
5
M01AB01
ATC
indometacin; systemic, rectal
1.7
6.3
129
786
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.4
6.3
313
2333
K76.6
ICD-10 Finland
Portal hypertension
+∞
6.3
6
*
K76.5
ICD-10 Finland
Hepatic veno-occlusive disease
+∞
6.3
6
*
K74.2
ICD-10 Finland
Hepatic fibrosis with hepatic sclerosis
+∞
6.3
6
*
D98
ICPC
Cholecystitis/cholelithiasis
4.3
6.2
21
49
A06AC01
ATC
ispaghula (psylla seeds); oral
1.3
6.2
441
3478
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.5
6.2
186
1248
I50.9
ICD-10 Finland
Heart failure, unspecified
1.5
6.2
202
1385
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.5
6.2
206
1416
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
2.2
6.2
57
262
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
3.4
6.1
27
80
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
2.2
6.1
58
267
F10.31
ICD-10 Finland
Withdrawal symptoms caused by alcohol with seizures
4.2
6.1
21
50
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
2.3
6.1
53
236
J01AA02
ATC
doxycycline; systemic
1.3
6.1
1619
15006
120
Kela drug reimbursment
Hypogammaglobulinaemia
12.5
6.1
10
8
UKC02
NOMESCO Finland
Cystoscopy
1.4
6.1
271
1978
N19
ICD-10 Finland
Unspecified kidney failure
2.3
6.1
53
237
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
2.2
6.1
60
281
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.5
6.0
223
1569
K57.2
ICD-10 Finland
Diverticular disease of large intestine with perforation and abscess
2.5
6.0
43
172
Y88.3
ICD-10 Finland
Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.3
6.0
52
229
K52.88
ICD-10 Finland
Other specified noninfective gastroenteritis and colitis
2.4
6.0
46
190
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.3
6.0
457
3639
D09
ICPC
Nausea
2.0
6.0
69
345

Mortality – FinRegistry

↥

Association

Association between endpoint K11_OTHINFLIV and mortality.

Females

Parameter HR [95% CI] p-value
K11_OTHINFLIV 2.225 [2.0, 2.48] < 0.001
Birth year 0.992 [0.98, 1.0] 0.051

During the follow-up period (1.1.1998 — 31.12.2019), 1869 out of 7701 females with K11_OTHINFLIV died.

Males

Parameter HR [95% CI] p-value
K11_OTHINFLIV 2.653 [2.38, 2.96] < 0.001
Birth year 0.989 [0.98, 1.0] 0.017

During the follow-up period (1.1.1998 — 31.12.2019), 2097 out of 6647 males with K11_OTHINFLIV died.

Mortality risk

Mortality risk for people of age

years, who have K11_OTHINFLIV.

N-year risk Females Males
1 0.17% 0.497%
5 1.218% 3.408%
10 2.785% 7.77%
15 5.34% 13.998%
20 9.612% 24.056%

Relationships between endpoints

↥

Index endpoint: K11_OTHINFLIV – Other inflammatory liver diseases

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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