This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
ILD medications: pirfenidone
ILD_PIRFENIDONE
No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
1 out of 7 registries used, show all original rules. |
315 |
4. Check minimum number of events
Min. number of events
3
|
315 |
5. Include endpointsNone |
315 |
6. Filter based on genotype QC (FinnGen only) |
315 |
Control definitions (FinnGen only)
- Control exclude
- ILD_MEDICATIONS
Extra metadata
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
ILD medications: pirfenidone
based on the number of shared cases.
Similar with more cases:
- ILD, hospital admissions
- Interstitial lung disease endpoints
- Other interstitial pulmonary diseases
- Interstitial lung disease
- Respiratory diseases principally affecting the interstitium, IBD co-morbidites
Similar with less cases:
None
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 315 | 82 | 233 |
| Unadjusted period prevalence (%) | 0.08 | 0.03 | 0.10 |
| Median age at first event (years) | 71.73 | 71.86 | 71.68 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 274
- Matched controls
- 2741
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
284
Kela drug reimbursment
Nintedanib and pirfenidone
+∞
323.0
272
*
J84.1
ICD-10 Finland
Other interstitial pulmonary diseases with fibrosis
12580.8
323.0
272
23
L04AX05
ATC
pirfenidone; oral
+∞
323.0
274
*
356
Kela drug reimbursment
Nintedanib and pirfenidone
+∞
293.1
226
*
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
165.3
162.0
160
23
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
50.4
105.1
127
46
L01XE31
ATC
[U] nintedanib; oral
+∞
75.6
69
*
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
39.6
73.4
93
35
UGC12
NOMESCO Finland
Flexible bronchoscopy
17.5
71.2
122
120
H02AB06
ATC
prednisolone; systemic
9.9
65.4
192
525
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
41.2
64.0
80
27
TGC00
NOMESCO Finland
Bronchial lavation
50.1
61.9
74
20
GD1AA
NOMESCO Finland
Thorax X-ray examination
8.5
51.7
225
958
XG410
NOMESCO Finland
Flow-volume spirometry
21.6
46.0
69
42
R03AC02
ATC
salbutamol; inhalant
6.6
45.3
197
767
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
14.7
39.6
69
61
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
9.0
39.2
92
146
GDA11
NOMESCO Finland
Thoracoscopic biopsy of lung
435.0
39.1
38
*
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
27.6
37.9
52
23
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
137.5
34.6
36
*
TGD04
NOMESCO Finland
Needle biopsy of the lungs in bronchoscopy
137.5
34.6
36
*
Z94.2
ICD-10 Finland
Lung transplant status
+∞
30.8
29
*
GDG10
NOMESCO Finland
Bilateral transplantation of lung
+∞
30.8
29
*
L04AA06
ATC
mycophenolic acid; systemic
+∞
30.8
29
*
R06.0
ICD-10 Finland
Dyspnoea
4.9
29.8
127
414
127
Kela drug reimbursment
Transplant complication
+∞
29.7
28
*
L01EX09
ATC
nintedanib; oral
+∞
28.6
27
*
Z51.5
ICD-10 Finland
Palliative care
9.0
28.5
64
90
R05
ICD-10 Finland
Cough
5.0
26.2
100
282
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
8.1
26.1
62
95
J96.1
ICD-10 Finland
Chronic respiratory failure
25.7
26.0
36
16
GD1AD
NOMESCO Finland
Thorax CT examination
9.6
25.8
55
70
J18.9
ICD-10 Finland
Pneumonia, unspecified
4.4
25.4
114
378
R4110
NOMESCO Finland
Physiotherapy
3.9
23.1
126
487
L04AX01
ATC
azathioprine; systemic
+∞
22.2
21
*
R03BA08
ATC
ciclesonide; inhalant
9.6
21.5
45
55
A02BC02
ATC
pantoprazole; systemic
3.9
21.4
216
1345
L04AD01
ATC
ciclosporin; systemic
+∞
21.1
20
*
R03BB04
ATC
tiotropium bromide; inhalant
6.4
20.4
57
108
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
3.7
20.2
111
422
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
13.7
19.2
33
27
GD1BT
NOMESCO Finland
Biopsy of lung with X-ray guidance
+∞
19.0
18
*
XX4BW
NOMESCO Finland
NA
+∞
19.0
18
*
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
10.1
18.9
38
43
R28
ICPC
Limited function/disability (R)
41.6
18.9
23
6
WX721
NOMESCO Finland
Oxygen concentrator therapy
+∞
17.9
17
*
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
4.3
17.8
74
217
J45.9
ICD-10 Finland
Asthma, unspecified
5.4
17.4
56
125
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
3.1
16.3
122
564
XQ858
NOMESCO Finland
Oxygen partial pressure measurement
26.4
16.3
22
9
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
4.4
16.0
63
174
GD1CD
NOMESCO Finland
Thorax extensive CT-examination
28.3
15.8
21
8
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.6
15.8
84
302
R05
ICPC
Cough
3.4
15.2
88
336
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
33.9
15.0
19
6
N02AA01
ATC
morphine; systemic, rectal
29.0
14.5
19
7
R99
ICPC
Respiratory disease other
15.6
14.3
23
16
UGC18
NOMESCO Finland
Flexible bronchoscopy with biopsy of lung
31.9
14.1
18
6
J01AA02
ATC
doxycycline; systemic
3.2
14.0
226
1637
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.7
13.5
148
840
XG466
NOMESCO Finland
Sleep oxymetry
8.5
13.0
28
36
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.8
12.8
109
528
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
6.8
12.7
32
52
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
6.8
12.7
32
52
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
3.0
12.4
87
373
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
3.1
12.1
79
320
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
4.4
11.9
44
113
WX892
NOMESCO Finland
Monitored bed care
4.2
11.6
46
126
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
5.0
11.6
38
86
R03AL02
ATC
salbutamol and ipratropium bromide; inhalant
125.0
11.5
12
*
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
12.7
11.0
19
16
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
4.4
10.8
40
103
D07AB02
ATC
hydrocortisone butyrate; topical
2.7
10.7
92
438
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
9.8
10.7
21
23
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
+∞
10.5
10
*
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
5.9
10.5
29
54
M05BA04
ATC
alendronic acid; oral
5.1
10.4
33
72
G47.3
ICD-10 Finland
Sleep apnoea
2.7
10.1
82
378
XJC10
NOMESCO Finland
Oesophageal pH monitoring
41.7
10.0
12
*
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
4.7
10.0
34
80
J01CA04
ATC
amoxicillin; systemic
2.5
10.0
211
1572
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
3.2
9.9
56
205
N02BE01
ATC
paracetamol; systemic, rectal
3.1
9.8
243
1971
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
8.0
9.6
21
28
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.5
9.6
94
478
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
2.5
9.6
90
448
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
6.9
9.5
23
36
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
+∞
9.4
9
*
GD1RA
NOMESCO Finland
Dynamic X-ray examination of respiratory organs with convetional X-ray picture
+∞
9.4
9
*
N02AX02
ATC
tramadol; systemic, rectal
2.3
9.3
133
809
R4190
NOMESCO Finland
Nutritional therapy
6.5
9.1
23
38
J01FA06
ATC
roxithromycin; oral
2.3
9.1
107
593
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.2
9.1
122
721
M05BA07
ATC
risedronic acid; oral
8.1
8.8
19
25
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.2
8.8
134
836
R03AK07
ATC
formoterol and budesonide; inhalant
3.2
8.8
48
170
J01MA14
ATC
moxifloxacin; systemic
4.0
8.5
34
94
R02
ICPC
Shortness of breath/dyspnoea
3.2
8.2
43
149
J45.0
ICD-10 Finland
Predominantly allergic asthma
6.2
8.2
21
36
J45.1
ICD-10 Finland
Nonallergic asthma
6.2
8.2
21
36
R03DC03
ATC
montelukast; oral
3.6
8.2
36
109
Z3226
NOMESCO Finland
Physiotherapist
2.6
8.1
64
285
N02AA05
ATC
oxycodone; systemic
2.7
8.0
58
247
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
4.1
8.0
30
79
J01FA10
ATC
azithromycin; systemic
2.1
7.7
136
884
R5140
NOMESCO Finland
Monitoring the use of the aid
3.0
7.6
46
173
SPAT1325
SPAT
Vaccination
2.1
7.4
124
783
E0000UV
ATC
NA
2.1
7.4
104
613
A02BC05
ATC
esomeprazole; systemic
2.1
7.4
120
753
R03AK06
ATC
salmeterol and fluticasone; inhalant
3.3
7.3
37
125
GDB11
NOMESCO Finland
Thoracoscopic wedge resection of lung
16.3
7.3
11
7
ZX108
NOMESCO Finland
Inhalation
30.9
7.2
9
*
R03AK08
ATC
formoterol and beclometasone; inhalant
9.2
7.1
14
16
J47
ICD-10 Finland
Bronchiectasis
10.4
7.1
13
13
A98
ICPC
Health maint/preventive medicine
4.5
7.0
265
2379
SAA01
NOMESCO Finland
Simple examination of mouth
2.0
6.9
177
1311
XJC02
NOMESCO Finland
Mesurement of oesophageal pressure and pressure profile of lower oesophageal sphincter
41.1
6.8
8
*
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
2.9
6.7
42
163
R2110
NOMESCO Finland
Giving the first information
4.1
6.7
25
66
ZXE00
NOMESCO Finland
One hour or less
2.0
6.6
116
741
XF400
NOMESCO Finland
ECG with 12 standard connections
2.4
6.6
62
300
PD4DE
NOMESCO Finland
Lower extremity artery ultrasound examination with Doppler method
7.7
6.5
14
19
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
71.4
6.5
7
*
I27.2
ICD-10 Finland
Other secondary pulmonary hypertension
71.4
6.5
7
*
SAA03
NOMESCO Finland
Extended examination of mouth
2.0
6.4
100
608
ZX109
NOMESCO Finland
Instruction on medicine inhalation technique
18.5
6.3
9
5
SPAT1262
SPAT
Handing over of treatment supplies
2.2
6.3
70
368
5AB14
NOMESCO Finland
NA
+∞
6.3
6
*
WX726
NOMESCO Finland
High-flow oxygen therapy
+∞
6.3
6
*
2AX04
NOMESCO Finland
NA
+∞
6.3
6
*
R03BA02
ATC
budesonide; inhalant
2.9
6.3
39
150
WX302
NOMESCO Finland
Thoracal epidural anesthesy
3.3
6.3
30
98
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.9
6.2
123
816
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: ILD_PIRFENIDONE – ILD medications: pirfenidone
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).