Interstitial lung disease endpoints

ILD_ENDPOINTS

interstitial lung disease: A diverse group of lung diseases that affect the lung parenchyma. They are characterized by an initial inflammation of pulmonary alveoli that extends to the interstitium and beyond leading to diffuse pulmonary fibrosis. Interstitial lung diseases are classified by their etiology (known or unknown causes), and radiological-pathological features.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

None

0 out of 7 registries used, show all original rules.

0

4. Check minimum number of events

None

0

5. Include endpoints

5925

6. Filter based on genotype QC (FinnGen only)

5925

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF2

Similar endpoints

List of similar endpoints to Interstitial lung disease endpoints based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

No data for upset plot.

No data for upset table.

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 38350 16182 21649
Only index persons 27651 12043 15608
Unadjusted period prevalence (%)
Whole population 0.54 0.46 0.60
Only index persons 0.53 0.44 0.60
Median age at first event (years)
Whole population 71.02 71.12 70.96
Only index persons 70.42 69.93 70.79

-FinnGen-

Key figures

All Female Male
Number of individuals 5925 2347 3578
Unadjusted period prevalence (%) 1.27 0.80 1.58
Median age at first event (years) 69.34 66.73 71.06

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
5266
Matched controls
52659
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
284
Kela drug reimbursment
Nintedanib and pirfenidone
+∞
323.0
467
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.6
323.0
3455
18317
356
Kela drug reimbursment
Nintedanib and pirfenidone
+∞
323.0
389
*
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
8.4
323.0
1892
3310
UGC12
NOMESCO Finland
Flexible bronchoscopy
10.9
323.0
1827
2438
TGC00
NOMESCO Finland
Bronchial lavation
37.0
323.0
1178
406
XG410
NOMESCO Finland
Flow-volume spirometry
9.0
323.0
786
1006
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
20.5
323.0
994
590
J84.1
ICD-10 Finland
Other interstitial pulmonary diseases with fibrosis
8968.6
323.0
2518
5
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
13505.8
323.0
2752
*
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
+∞
323.0
1440
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
4.2
323.0
2636
10196
H02AB06
ATC
prednisolone; systemic
5.2
323.0
3854
18200
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
26.9
323.0
1795
991
L04AX05
ATC
pirfenidone; oral
+∞
321.1
305
*
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
4.9
316.9
1185
2939
R06.0
ICD-10 Finland
Dyspnoea
3.3
305.5
2143
9150
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
6.4
292.7
842
1519
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
9.6
262.4
565
649
L04AX01
ATC
azathioprine; systemic
8.2
251.2
595
801
R03AC02
ATC
salbutamol; inhalant
2.7
249.1
3125
18566
GD1AD
NOMESCO Finland
Thorax CT examination
6.6
237.1
655
1102
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.6
219.0
2332
12277
L01XE31
ATC
[U] nintedanib; oral
+∞
205.5
196
*
J96.1
ICD-10 Finland
Chronic respiratory failure
9.0
202.8
450
538
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
5.0
201.7
705
1566
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
4.4
201.5
817
2115
GDA11
NOMESCO Finland
Thoracoscopic biopsy of lung
66.4
197.3
229
36
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
27.8
195.7
272
103
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
5.1
190.1
658
1441
L04AA06
ATC
mycophenolic acid; systemic
13.6
177.4
317
246
TGD04
NOMESCO Finland
Needle biopsy of the lungs in bronchoscopy
45.2
175.0
217
50
J84.0
ICD-10 Finland
Alveolar and parietoalveolar conditions
+∞
168.6
161
*
J01MA14
ATC
moxifloxacin; systemic
3.6
163.2
832
2604
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
3.4
161.4
914
3103
48499
ICD-8 Finland
Acute interstitial pneumonia
+∞
150.7
144
*
P01BA02
ATC
hydroxychloroquine; oral
3.9
147.7
683
1959
R03BB04
ATC
tiotropium bromide; inhalant
3.0
146.4
976
3698
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
4.7
144.8
537
1250
A02BC02
ATC
pantoprazole; systemic
2.2
141.9
3663
27103
L01EX09
ATC
nintedanib; oral
+∞
136.0
130
*
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
4.3
131.5
529
1330
J92.0
ICD-10 Finland
Pleural plaque with presence of asbestos
6.3
121.6
342
574
R05
ICD-10 Finland
Cough
2.4
120.9
1245
6008
5150X
ICD-9 Finland
Postinflammatory pulmonary fibrosis[FIBROSIS PULMONUM E CAUSA IGNOTA]
+∞
118.1
113
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.4
116.7
1194
5728
C03CA01
ATC
furosemide; systemic
2.0
116.5
2215
13992
M05BA04
ATC
alendronic acid; oral
3.1
116.2
720
2561
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
4.9
116.2
405
877
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.4
110.8
1162
5624
GDG10
NOMESCO Finland
Bilateral transplantation of lung
371.6
109.7
110
*
Z94.2
ICD-10 Finland
Lung transplant status
110.6
109.4
119
11
GD1CD
NOMESCO Finland
Thorax extensive CT-examination
10.8
93.9
186
178
J01MA12
ATC
levofloxacin; systemic
2.1
90.7
1284
7035
J45.9
ICD-10 Finland
Asthma, unspecified
2.2
90.1
1078
5486
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
2.4
89.8
889
4128
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
2.9
88.5
595
2212
GD1BT
NOMESCO Finland
Biopsy of lung with X-ray guidance
434.6
86.3
86
*
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.0
85.9
1421
8261
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
4.8
85.3
300
652
J61
ICD-10 Finland
Pneumoconiosis due to asbestos and other mineral fibres
11.5
85.1
163
146
J01AA02
ATC
doxycycline; systemic
1.9
83.2
4007
33172
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.6
82.0
690
2928
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
3.2
81.6
469
1564
J47
ICD-10 Finland
Bronchiectasis
5.8
79.8
237
424
A07EC01
ATC
sulfasalazine; oral, rectal
2.9
78.9
540
2022
J43.9
ICD-10 Finland
Emphysema, unspecified
6.1
77.7
220
371
R4110
NOMESCO Finland
Physiotherapy
1.9
76.6
1521
9382
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.0
76.0
1208
6861
R02
ICPC
Shortness of breath/dyspnoea
2.3
75.5
790
3740
XQ858
NOMESCO Finland
Oxygen partial pressure measurement
9.1
75.0
163
185
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.7
73.6
2397
17260
R03BA08
ATC
ciclesonide; inhalant
2.9
73.4
497
1846
R50.9
ICD-10 Finland
Fever, unspecified
2.2
72.8
861
4313
I50.9
ICD-10 Finland
Heart failure, unspecified
2.0
70.7
1097
6145
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.9
70.2
453
1630
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
3.9
69.4
307
830
L04AA13
ATC
leflunomide; oral
5.2
69.0
223
441
TPH04
NOMESCO Finland
Cathetrisation of vein
1.9
68.8
1261
7508
J01FA06
ATC
roxithromycin; oral
1.7
68.2
2057
14374
R03AK08
ATC
formoterol and beclometasone; inhalant
4.2
67.5
272
676
R04.2
ICD-10 Finland
Haemoptysis
3.5
65.7
329
985
XG466
NOMESCO Finland
Sleep oxymetry
3.9
65.5
286
764
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
65.4
1677
11123
WX892
NOMESCO Finland
Monitored bed care
2.5
65.1
561
2392
R03AK06
ATC
salmeterol and fluticasone; inhalant
2.1
64.7
872
4599
Z01.8
ICD-10 Finland
Other specified special examinations
1.9
64.6
1168
6899
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.9
62.8
1101
6418
J45.1
ICD-10 Finland
Nonallergic asthma
2.7
61.9
456
1776
H02AB07
ATC
prednisone; oral
2.0
61.2
864
4632
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
20.8
60.1
90
44
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.6
59.9
481
1968
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
2.8
59.6
417
1575
XX4BW
NOMESCO Finland
NA
47.9
58.4
71
15
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
5.0
55.5
186
383
L04AD01
ATC
ciclosporin; systemic
5.4
55.4
173
329
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.9
55.1
950
5473
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
7.9
53.7
126
163
M05.9
ICD-10 Finland
Seropositive rheumatoid arthritis, unspecified
4.4
53.6
202
470
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.7
53.2
1421
9417
WW200
NOMESCO Finland
Immunization
4.1
53.1
219
556
J01CA04
ATC
amoxicillin; systemic
1.6
53.0
3782
32215
127
Kela drug reimbursment
Transplant complication
6.1
52.7
148
247
R03AK07
ATC
formoterol and budesonide; inhalant
1.9
52.5
914
5276
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
5.2
52.4
170
338
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
2.9
51.1
326
1158
R81
ICPC
Pneumonia
3.4
50.6
256
772
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
5.0
50.2
168
346
UGC18
NOMESCO Finland
Flexible bronchoscopy with biopsy of lung
10.5
49.9
99
96
R28
ICPC
Limited function/disability (R)
5.9
49.3
143
249
ZX120
NOMESCO Finland
Intravenous
2.2
49.0
577
2849
R05
ICPC
Cough
1.8
48.5
1091
6833
ZX108
NOMESCO Finland
Inhalation
9.5
48.3
101
108
ZX109
NOMESCO Finland
Instruction on medicine inhalation technique
7.9
48.0
112
144
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
3.6
47.2
226
652
GX1K5
NOMESCO Finland
Diffusion capacity
30.3
47.1
63
21
J82
ICD-10 Finland
Pulmonary eosinophilia, not elsewhere classified
17.0
46.3
74
44
XG474
NOMESCO Finland
Exhalation nntrogen oxide
4.4
46.0
172
398
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
3.4
45.5
232
703
N02AX02
ATC
tramadol; systemic, rectal
1.5
45.2
2190
16727
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.9
45.2
745
4199
R99
ICPC
Respiratory disease other
4.7
44.0
155
338
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.4
43.7
404
1775
R03BA02
ATC
budesonide; inhalant
1.8
42.2
850
5117
A02BC01
ATC
omeprazole; systemic
1.6
42.0
1510
10694
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.6
41.5
1557
11137
WX721
NOMESCO Finland
Oxygen concentrator therapy
22.9
40.9
59
26
J84
ICD-10 Finland
Other interstitial pulmonary diseases
144.4
40.8
43
*
A02BC05
ATC
esomeprazole; systemic
1.5
40.6
1940
14656
A07AA02
ATC
nystatin; oral
2.3
40.2
392
1768
C07AB07
ATC
bisoprolol; oral
1.5
39.8
2696
21902
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.9
39.6
694
3981
R03BA01
ATC
beclometasone; inhalant
1.8
39.3
726
4237
L88
ICPC
Rheumatoid/seropositive arthritis
3.1
39.2
227
756
I50.0
ICD-10 Finland
Congestive heart failure
2.0
39.2
561
2986
J99.0*M05.1
ICD-10 Finland
Rheumatoid lung disease
137.7
38.8
41
*
R03BA05
ATC
fluticasone; inhalant
1.7
37.6
839
5198
NH3EA
NOMESCO Finland
Feet X-ray examination with load
4.4
37.3
138
317
D86.0
ICD-10 Finland
Sarcoidosis of lung
5.4
36.7
113
213
WZC30
NOMESCO Finland
Teaching
1.8
36.6
686
4020
R03AL06
ATC
olodaterol and tiotropium bromide; inhalant
3.8
36.6
162
439
GD5BD
NOMESCO Finland
Thorax and upper abdomen combined extensive CT examination of
3.5
36.1
177
521
R03DC03
ATC
montelukast; oral
1.8
36.1
671
3918
XGX32
NOMESCO Finland
Bronchoscopic ultrasonography
7.1
35.8
89
127
XF400
NOMESCO Finland
ECG with 12 standard connections
1.6
35.2
969
6361
R5140
NOMESCO Finland
Monitoring the use of the aid
1.9
35.1
549
3016
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
2.3
35.0
352
1610
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.5
35.0
1493
10909
GX1D5
NOMESCO Finland
Flow volume spirometry
43.3
35.0
43
10
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
34.9
2120
16684
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.8
34.8
626
3611
J99.1
ICD-10 Finland
Respiratory disorders in other diffuse connective tissue disorders
124.2
34.7
37
*
J01FA10
ATC
azithromycin; systemic
1.4
34.6
2304
18448
TPH07
NOMESCO Finland
Cathetrisation of artery
1.8
34.3
600
3429
R03AK03
ATC
[D] fenoterol & other drugs for obstructive airway dis; inhalant
2.1
34.2
419
2091
GDA10
NOMESCO Finland
Biopsy of lung
15.7
34.2
56
36
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
1.9
34.0
557
3111
J92.9
ICD-10 Finland
Pleural plaque without asbestos
4.5
33.9
123
277
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.9
33.6
514
2799
E0000UV
ATC
NA
1.5
33.2
1754
13381
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
7.9
32.9
76
97
J67.9
ICD-10 Finland
Hypersensitivity pneumonitis due to unspecified organic dust
21.0
32.6
48
23
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
3.4
32.5
166
505
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
32.5
32.2
42
13
WX725
NOMESCO Finland
Noninvasive ventilation
2.5
32.1
259
1058
F1246
NOMESCO Finland
NA
20.6
31.7
47
23
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.1
31.5
391
1961
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.6
31.3
959
6453
L04AA01
ATC
[U] ciclosporin; systemic
4.4
31.2
115
264
J20
ICD-10 Finland
Acute bronchitis
2.0
31.1
446
2370
G47.3
ICD-10 Finland
Sleep apnoea
1.6
30.7
974
6607
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
3.9
30.7
131
345
XW000
NOMESCO Finland
Bone marrow biopsy
2.4
30.6
268
1141
M34.1
ICD-10 Finland
CR(E)ST syndrome
12.0
30.6
56
47
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
2.1
30.5
374
1865
R03AL02
ATC
salbutamol and ipratropium bromide; inhalant
4.9
30.3
101
209
M05BA07
ATC
risedronic acid; oral
2.7
30.3
214
811
J43.8
ICD-10 Finland
Other emphysema
11.5
30.0
56
49
D07AC01
ATC
betamethasone; topical
1.4
29.8
1605
12222
J01FF01
ATC
clindamycin; systemic
1.5
29.5
1254
9090
JN4BD
NOMESCO Finland
Extensive body CT
1.7
29.4
634
3862
J94.1
ICD-10 Finland
Fibrothorax
37.2
29.3
37
10
M34.9
ICD-10 Finland
Systemic sclerosis, unspecified
12.8
29.3
52
41
I27.9
ICD-10 Finland
Pulmonary heart disease, unspecified
6.8
28.8
73
108
GDB11
NOMESCO Finland
Thoracoscopic wedge resection of lung
7.9
28.8
66
84
XF600
NOMESCO Finland
Bloodpressure measurement
2.0
28.6
367
1866
XX9XE
NOMESCO Finland
Other ultrasound examination
6.0
28.6
80
135
M01CB01
ATC
sodium aurothiomalate; parenteral
4.0
28.2
115
291
R06AE07
ATC
cetirizine; oral
1.4
28.1
1742
13593
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
3.9
27.9
117
304
XG460
NOMESCO Finland
Short time oxymetry
3.5
27.7
135
397
N02BE01
ATC
paracetamol; systemic, rectal
1.5
27.6
4203
38404
A03
ICPC
Fever
1.7
27.4
574
3466
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.1
27.3
338
1693
2AX04
NOMESCO Finland
NA
53.6
27.2
32
6
GD1RA
NOMESCO Finland
Dynamic X-ray examination of respiratory organs with convetional X-ray picture
23.9
26.9
38
16
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
3.3
26.9
137
417
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
2.2
26.6
275
1273
WX726
NOMESCO Finland
High-flow oxygen therapy
24.8
26.5
37
15
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
1.8
26.4
530
3155
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.5
26.4
895
6143
J80
ICD-10 Finland
Adult respiratory distress syndrome
9.6
26.4
54
57
J01DB01
ATC
cefalexin; oral
1.4
26.3
3819
34353
I27.2
ICD-10 Finland
Other secondary pulmonary hypertension
6.6
26.2
68
104
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
8.5
25.9
57
68
L04AB01
ATC
etanercept; parenteral
4.9
25.5
85
177
J96.0
ICD-10 Finland
Acute respiratory failure
3.7
25.4
114
314
TDM10
NOMESCO Finland
Puncture of maxillary antrum
2.7
25.3
179
678
J70.2
ICD-10 Finland
Acute drug-induced interstitial lung disorders
12.6
25.3
45
36
L04AB04
ATC
adalimumab; parenteral
4.4
25.1
93
216
5169X
ICD-9 Finland
Other alveolar and parietoalveolar pneumopathy, Unspecified alveolar and parietoalveolar pneumopathy
+∞
25.0
24
*
XW5WT
NOMESCO Finland
Other blood specimen with radiologicl guidance
12.3
25.0
45
37
R06.2
ICD-10 Finland
Wheezing
2.4
24.9
226
982
WX872
NOMESCO Finland
Intensive care
2.1
24.9
298
1473
M04AA01
ATC
allopurinol; systemic
1.6
24.8
810
5501
WX408
NOMESCO Finland
General anesthesy, balanced
1.4
24.8
1259
9410
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.4
24.8
1436
11007
WZA10
NOMESCO Finland
Long statement of health and health related matters
4.8
24.7
83
174
WX722
NOMESCO Finland
PEEP
2.1
24.7
276
1322
H02AB04
ATC
methylprednisolone; systemic
1.6
24.7
693
4533
RS123
NOMESCO Finland
NA
32.2
24.6
32
10
A02BC03
ATC
lansoprazole; oral
1.4
24.2
1445
11125
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.6
24.2
710
4696
F2680
NOMESCO Finland
NA
13.2
24.1
42
32
B01AA03
ATC
warfarin; systemic
1.4
24.0
1286
9698
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
2.3
24.0
234
1055
Z51.5
ICD-10 Finland
Palliative care
1.9
24.0
373
2037
J01FA15
ATC
telithromycin; oral
1.8
23.6
424
2433
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
23.4
1682
13365
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.8
23.4
418
2397
A01AB09
ATC
miconazole; local oral
1.8
23.3
444
2595
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.4
23.3
1918
15587
N03AX16
ATC
pregabalin; oral
1.5
23.2
1074
7864
XJC10
NOMESCO Finland
Oesophageal pH monitoring
6.7
23.1
59
89
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
1.6
22.9
685
4546
TND11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in joint, wrist or hand
4.3
22.9
86
203
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.4
22.7
1388
10710
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
2.4
22.7
199
850
3A006
NOMESCO Finland
NA
230.9
22.6
23
*
J01FA09
ATC
clarithromycin; systemic
1.4
22.6
1237
9352
J99.1*M35.0
ICD-10 Finland
Respiratory disorders in sicca syndrome [Sjögren]
120.5
22.6
24
*
J99.0
ICD-10 Finland
Rheumatoid lung disease
120.5
22.6
24
*
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
3.1
22.3
124
405
XG405
NOMESCO Finland
Education on PEF monitoring
3.6
22.2
101
283
M13.9
ICD-10 Finland
Arthritis, unspecified
1.9
22.2
333
1796
L01AA01
ATC
cyclophosphamide; systemic
6.7
22.0
56
84
AN1
HP
Coronary angiography
1.5
21.9
732
4987
5163A
ICD-9 Finland
Other alveolar and parietoalveolar pneumopathy, Idiopathic fibrosing alveolitis
+∞
21.9
21
*
C01DA14
ATC
isosorbide mononitrate; oral
1.5
21.7
1017
7453
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
3.3
21.6
111
342
R03AC03
ATC
terbutaline; inhalant
1.6
21.5
589
3822
XQ841
NOMESCO Finland
Examination of dermatosis with microscope
31.3
21.4
28
9
J45.8
ICD-10 Finland
Mixed asthma
2.5
21.1
168
684
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.5
21.0
751
5193
JN4AD
NOMESCO Finland
Body CT examination
1.8
21.0
411
2424
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
21.0
1536
12189
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.5
20.8
727
5003
SPAT1262
SPAT
Handing over of treatment supplies
1.5
20.7
938
6822
UJF32
NOMESCO Finland
Coloscopy
1.4
20.6
1275
9830
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.0
20.5
284
1488
J43.2
ICD-10 Finland
Centrilobular emphysema
7.8
20.5
47
61
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
1.9
20.2
295
1574
M05
ICD-10 Finland
Seropositive rheumatoid arthritis
5.0
20.1
65
132
M81.9
ICD-10 Finland
Osteoporosis, unspecified
2.2
20.0
209
973
Z57.2
ICD-10 Finland
Occupational exposure to dust
7.1
20.0
49
70
RK320
NOMESCO Finland
NA
4.4
20.0
73
168
L04AA24
ATC
abatacept; parenteral
9.8
20.0
40
41
J12.8
ICD-10 Finland
Other viral pneumonia
5.4
20.0
60
112
SPAT1325
SPAT
Vaccination
1.3
20.0
1751
14273
GAA31
NOMESCO Finland
Thoracoscopy
7.7
20.0
46
60
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
2.1
19.7
240
1195
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.6
19.7
503
3200
N02AA05
ATC
oxycodone; systemic
1.5
19.7
789
5588
120
Kela drug reimbursment
Hypogammaglobulinaemia
16.4
19.6
31
19
R03AK11
ATC
formoterol and fluticasone; inhalant
2.8
19.6
129
471
D07AB02
ATC
hydrocortisone butyrate; topical
1.4
19.3
1206
9293
7140A
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Rheumatoid arthritis[ARTHRITIS RHEUMATOIDES SEROPOSITIVA]
3.4
19.3
93
274
M33.2
ICD-10 Finland
Polymyositis
11.7
19.2
35
30
I27.8
ICD-10 Finland
Other specified pulmonary heart diseases
8.0
19.2
43
54
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
1.9
19.0
302
1662
GD2SN
NOMESCO Finland
Lung ventilation SPECT
5.0
19.0
61
123
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
3.0
19.0
109
363
5AB14
NOMESCO Finland
NA
14.0
19.0
32
23
WX110
NOMESCO Finland
Local anesthesy
1.3
18.9
2888
25424
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
2.9
18.8
116
407
J06BA01
ATC
immunoglobulins, normal human, for extravascular adm.; systemic
17.1
18.7
29
17
SPAT1263
SPAT
Sampling
1.3
18.5
1908
15878
GD5AD
NOMESCO Finland
Thorax and upper abdomen combined CT examination of
3.5
18.4
87
253
J13
ICD-10 Finland
Pneumonia due to Streptococcus pneumoniae
4.1
18.3
71
174
M35.1
ICD-10 Finland
Other overlap syndromes
7.1
18.2
44
62
M33.1
ICD-10 Finland
Other dermatomyositis
21.8
18.1
26
12
J05AB11
ATC
valaciclovir; oral
1.6
18.0
548
3643
D86.9
ICD-10 Finland
Sarcoidosis, unspecified
5.0
18.0
57
114
206
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
1.4
17.9
1172
9086
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
3.1
17.9
100
329
R03BB01
ATC
ipratropium bromide; inhalant
1.9
17.9
259
1378
J15.8
ICD-10 Finland
Other bacterial pneumonia
4.5
17.9
63
141
TNB11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in shoulder joint
5.9
17.8
49
83
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
1.8
17.7
295
1651
I26.0
ICD-10 Finland
Pulmonary embolism with mention of acute cor pulmonale
2.6
17.7
129
499
R03AC12
ATC
salmeterol; inhalant
1.9
17.7
247
1296
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
2.1
17.7
204
994
WX002
NOMESCO Finland
Sedation and analgesia
1.4
17.7
931
6944
ZXA10
NOMESCO Finland
Bilateral
1.4
17.6
900
6674
M34.0
ICD-10 Finland
Progressive systemic sclerosis
14.6
17.6
29
20
J67.0
ICD-10 Finland
Farmer lung
12.5
17.6
31
25
C03DA01
ATC
spironolactone; oral
1.5
17.5
576
3899
M05.1
ICD-10 Finland
Rheumatoid lung disease
180.5
17.5
18
*
J99.1*M33.2
ICD-10 Finland
Respiratory disorders in polymyositis
180.5
17.5
18
*
GD1UN
NOMESCO Finland
Lung circulation SPECT
5.0
17.4
55
110
D86.2
ICD-10 Finland
Sarcoidosis of lung with sarcoidosis of lymph nodes
4.5
17.3
61
137
J46
ICD-10 Finland
Status asthmaticus
2.5
17.2
138
567
D80.1
ICD-10 Finland
Nonfamilial hypogammaglobulinaemia
10.4
17.1
33
32
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.6
17.1
522
3471
R07.4
ICD-10 Finland
Chest pain, unspecified
1.3
17.0
1268
10021
M10.9
ICD-10 Finland
Gout, unspecified
1.7
17.0
374
2282
XF402
NOMESCO Finland
ECG with work load test
1.5
17.0
564
3825
XG499
NOMESCO Finland
Other fysiological examination of respiatory function
7.1
17.0
41
58
E000001
ATC
NA
1.4
17.0
844
6227
RK110
NOMESCO Finland
NA
4.3
16.9
63
149
D07AC13
ATC
mometasone; topical
1.4
16.9
1234
9723
UJF30
NOMESCO Finland
Ileoscopy through colon
1.6
16.9
415
2610
J70.0
ICD-10 Finland
Acute pulmonary manifestations due to radiation
10.7
16.9
32
30
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
2.4
16.9
142
598
XX1XW
NOMESCO Finland
Extensive written report from radiologist
2.7
16.9
114
425
B02.9
ICD-10 Finland
Zoster without complication
1.8
16.8
283
1589
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.3
16.8
1281
10163
R03AK10
ATC
vilanterol and fluticasone furoate; inhalant
2.2
16.7
163
738
M34.8
ICD-10 Finland
Other forms of systemic sclerosis
35.1
16.6
21
6
R01AD12
ATC
fluticasone furoate; nasal
1.4
16.6
966
7323
J18
ICD-10 Finland
Pneumonia, organism unspecified
4.3
16.6
61
143
J01MA02
ATC
ciprofloxacin; systemic
1.3
16.5
1893
15923
XPX04
NOMESCO Finland
Angioscopy
8.6
16.4
35
41
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
1.7
16.3
357
2175
C09AA05
ATC
ramipril; oral
1.3
16.3
1355
10883
GX2C5
NOMESCO Finland
Short-lasting oximetry
14.3
16.3
27
19
J01DA01
ATC
[U] cefalexin; systemic
1.3
16.2
2835
25158
N02AA01
ATC
morphine; systemic, rectal
3.0
16.2
94
318
M05BX04
ATC
denosumab; parenteral
1.9
16.2
253
1387
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
2.4
16.1
136
572
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
1.7
16.1
381
2372
XQ800
NOMESCO Finland
Prick test
1.9
16.1
242
1306
R29
ICPC
Respiratory symptom/complaint other
1.9
16.1
256
1412
R01AD09
ATC
mometasone; nasal
1.3
16.0
1660
13750
M81.4
ICD-10 Finland
Drug-induced osteoporosis
6.3
16.0
42
67
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
1.7
16.0
322
1917
J93.1
ICD-10 Finland
Other spontaneous pneumothorax
4.0
16.0
63
158
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.5
15.8
493
3292
R03DA04
ATC
theophylline; systemic, rectal
1.7
15.7
321
1916
I20.81
ICD-10 Finland
Other angina pectoris stenosed coronary artery
1.5
15.7
512
3458
AK3
HP
BLTX (both lung transplants)
+∞
15.6
15
*
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
4.2
15.5
59
143
M25.5
ICD-10 Finland
Pain in joint
1.4
15.5
1052
8177
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
1.5
15.5
630
4459
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.4
15.5
1032
7999
I73.0
ICD-10 Finland
Raynaud syndrome
3.4
15.5
75
224
SPAT1255
SPAT
Intravenous administration of medicine
1.7
15.5
312
1858
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
2.5
15.4
123
505
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
1.6
15.3
365
2278
WX882
NOMESCO Finland
High dependency care
2.3
15.3
145
648
N03AX12
ATC
gabapentin; oral
1.5
15.0
642
4589
UDQ12
NOMESCO Finland
Flexible laryngoscopy
1.8
15.0
245
1361
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.3
15.0
1371
11141
JC2AB
NOMESCO Finland
Oesophagus X-ray examination with contrast
3.8
15.0
62
163
M05BB03
ATC
alendronic acid and colecalciferol; oral
2.4
14.9
131
563
N05CF01
ATC
zopiclone; oral
1.3
14.9
1549
12815
R94.2
ICD-10 Finland
Abnormal results of pulmonary function studies
4.7
14.8
50
108
D07AB08
ATC
desonide; topical
1.6
14.8
439
2899
A28
ICPC
Limited function/disability NOS
1.4
14.5
828
6241
TGD00
NOMESCO Finland
Needle biopsy of lung
5.3
14.5
43
81
M33.9
ICD-10 Finland
Dermatopolymyositis, unspecified
10.8
14.5
27
25
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
2.3
14.4
134
594
R03AC13
ATC
formoterol; inhalant
1.8
14.4
236
1312
R4190
NOMESCO Finland
Nutritional therapy
2.3
14.4
137
615
318
Kela drug reimbursment
Teriparatide
5.6
14.3
41
74
B25.9
ICD-10 Finland
Cytomegaloviral disease, unspecified
11.4
14.2
26
23
R01AD08
ATC
fluticasone; nasal
1.3
14.0
1031
8099
1240
FHL
Bronchoscopy
2.9
14.0
83
287
R05FB02
ATC
cough suppressants and expectorants
1.3
13.9
1713
14450
J96.9
ICD-10 Finland
Respiratory failure, unspecified
4.3
13.9
51
120
ZXA00
NOMESCO Finland
Right side
1.3
13.9
1310
10666
GX1E5
NOMESCO Finland
Flow volume spirometry and bronchodilation test
12.7
13.9
24
19
J02AC01
ATC
fluconazole; systemic
1.3
13.8
1346
11013
GX2D5
NOMESCO Finland
Sleep oximetry
7.8
13.8
31
40
XJC02
NOMESCO Finland
Mesurement of oesophageal pressure and pressure profile of lower oesophageal sphincter
4.7
13.7
46
99
5BA08
NOMESCO Finland
NA
4.5
13.7
48
108
I25.0
ICD-10 Finland
Atherosclerotic cardiovascular disease, so described
1.6
13.7
368
2369
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
4.5
13.7
47
104
J98.4
ICD-10 Finland
Other disorders of lung
9.1
13.7
28
31
1CX01
NOMESCO Finland
NA
9.7
13.7
27
28
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
3.1
13.7
74
241
XX3DW
NOMESCO Finland
Time consuming IT work
1.5
13.6
461
3133
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.3
13.6
1907
16335
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
1.8
13.6
225
1257
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
2.1
13.6
144
680
1XC02
NOMESCO Finland
NA
4.0
13.5
53
133
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
2.0
13.5
162
804
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.6
13.5
323
2017
WX302
NOMESCO Finland
Thoracal epidural anesthesy
1.8
13.5
239
1368
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
1.7
13.4
297
1815
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.6
13.3
353
2265
N17.9
ICD-10 Finland
Acute renal failure, unspecified
1.8
13.3
214
1185
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.8
13.3
236
1348
B01AB05
ATC
enoxaparin; parenteral
1.3
13.3
1398
11539
J93.8
ICD-10 Finland
Other pneumothorax
5.0
13.3
42
85
4040
NOMESCO Finland
NA
21.2
13.3
19
9
M31.3
ICD-10 Finland
Wegener granulomatosis
6.2
13.3
35
57
L04AC07
ATC
tocilizumab; parenteral
11.5
13.3
24
21
D07XC01
ATC
betamethasone, combinations; topical
1.5
13.3
534
3768
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
1.6
13.2
372
2423
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
1.9
13.2
197
1064
D80.9
ICD-10 Finland
Immunodeficiency with predominantly antibody defects, unspecified
12.1
13.1
23
19
M79.6
ICD-10 Finland
Pain in limb
1.3
13.0
1458
12135
D64.9
ICD-10 Finland
Anaemia, unspecified
1.5
13.0
536
3805
GDA97
NOMESCO Finland
Other thoracoscopic incision, excision of lesion or repair of lung
28.4
12.9
17
6
FXD00
NOMESCO Finland
Use of ECHLA without concurrent surgical procedure
19.1
12.9
19
10
R03AK04
ATC
salbutamol and sodium cromoglicate; inhalant
3.2
12.9
66
207
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
12.9
1377
11386
71238
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Arthritis rheumatoides alia definita
3.5
12.9
58
165
E84.0
ICD-10 Finland
Cystic fibrosis with pulmonary manifestations
50.1
12.8
15
*
H05AA02
ATC
teriparatide; parenteral
5.6
12.6
36
65
E84.9
ICD-10 Finland
Cystic fibrosis, unspecified
70.0
12.6
14
*
J17.1*B25.0
ICD-10 Finland
Cytomegaloviral pneumonitis
70.0
12.6
14
*
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.5
12.6
393
2624
J99.1*M31.3
ICD-10 Finland
Respiratory disorders in Wegener's granulomatosis
17.3
12.5
19
11
J05AB01
ATC
aciclovir; systemic
1.4
12.5
807
6203
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
1.6
12.5
345
2239
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
1.7
12.5
278
1704
EBA15
NOMESCO Finland
Extraction of large number of teeth
1.9
12.5
175
925
291
Kela drug reimbursment
Tofacitinib
10.0
12.4
24
24
J02AC03
ATC
voriconazole; systemic
9.3
12.4
25
27
J42
ICD-10 Finland
Unspecified chronic bronchitis
2.9
12.4
75
264
M01CB03
ATC
auranofin; oral
3.9
12.4
49
125
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.3
12.4
845
6551
H25.1
ICD-10 Finland
Senile nuclear cataract
1.3
12.3
1431
11948
J98.9
ICD-10 Finland
Respiratory disorder, unspecified
9.6
12.2
24
25
XX6XT
NOMESCO Finland
Other intravascular therapy with radiological guidance
9.6
12.2
24
25
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
1.7
12.2
280
1731
81
HP
Angiography of the heart and coronary arteries
1.5
12.2
410
2785
A46
ICD-10 Finland
Erysipelas
1.4
12.1
675
5056
PD4DE
NOMESCO Finland
Lower extremity artery ultrasound examination with Doppler method
2.3
12.1
111
492
R24
ICPC
Haemoptysis
4.3
12.0
43
100
XF614
NOMESCO Finland
Measurement of pulmonary artery pressure
9.3
12.0
24
26
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
1.9
11.8
168
894
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.3
11.8
1377
11492
GDA98
NOMESCO Finland
Other bronchoscopic incision, excision of lesion or repair of lung
3.6
11.8
51
141
7931A
ICD-9 Finland
Nonspecific abnormal findings on radiological and other examination of body structure, Lung field
4.4
11.8
41
93
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
2.9
11.7
69
239
TNH11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in ankle joint or foot joint
3.5
11.7
53
152
M35.8
ICD-10 Finland
Other specified systemic involvement of connective tissue
9.6
11.7
23
24
Z31.5
ICD-10 Finland
Genetic counselling
2.1
11.7
125
593
J45
ICD-10 Finland
Asthma
1.5
11.7
362
2414
H02AB09
ATC
hydrocortisone; systemic
2.4
11.5
100
429
NJ3CG
NOMESCO Finland
Extensive MRI examination of extremities with median high magnet
6.5
11.5
29
45
NDG30
NOMESCO Finland
Fusion of wrist, total
5.3
11.4
34
65
2770A
ICD-9 Finland
Other and unspecified disorders of metabolism, Cystic fibrosis
120.2
11.4
12
*
A02BA02
ATC
ranitidine; systemic
1.3
11.4
941
7500
XG404
NOMESCO Finland
Peak expiratory flow (PEF) measurement
4.0
11.3
44
111
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.3
11.3
1355
11332
XX2XT
NOMESCO Finland
Other injection with other radiological guidance
5.8
11.3
31
54
J01GB01
ATC
tobramycin; inhalant, parenteral
15.0
11.3
18
12
M05BA06
ATC
ibandronic acid; systemic
2.4
11.2
95
403
R74
ICPC
Upper respiratory infection acute
1.3
11.2
805
6283
M54.5
ICD-10 Finland
Low back pain
1.3
11.2
1244
10310
NG1DA
NOMESCO Finland
X-ray of knees
2.5
11.1
86
351
R4120
NOMESCO Finland
Occupational therapy
1.6
11.1
264
1651
Y57
ICD-10 Finland
Adverse effects in the therapeutic use of other and unspecified drugs and medicaments
2.4
11.0
91
383
ED1AA
NOMESCO Finland
Mandipular X-ray examination
4.4
11.0
38
86
WX740
NOMESCO Finland
Nitrogen oxide therapy
9.2
11.0
22
24
S97
ICPC
Chronic ulcer skin
1.6
10.9
269
1694
E000002
ATC
NA
1.5
10.9
394
2718
Z94.3
ICD-10 Finland
Heart and lungs transplant status
43.4
10.9
13
*
L04AA17
ATC
[U] adalimumab; parenteral
6.2
10.9
28
45
C10AA03
ATC
pravastatin; oral
1.5
10.9
373
2547
J10.1
ICD-10 Finland
Influenza with other respiratory manifestations, seasonal influenza virus identified
2.6
10.9
76
291
JN4KR
NOMESCO Finland
Whole body very extensive metabolic PET with CT
3.7
10.8
45
121
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
1.5
10.8
328
2179
I27.0
ICD-10 Finland
Primary pulmonary hypertension
6.5
10.8
27
42
SPAT1260
SPAT
Consultation of another employee
1.3
10.7
763
5941
WX402
NOMESCO Finland
General anaesthesia
1.4
10.7
598
4483
A03FA01
ATC
metoclopramide; systemic, rectal
1.3
10.7
853
6758
RS230
NOMESCO Finland
NA
4.7
10.7
35
75
I50.1
ICD-10 Finland
Left ventricular failure
1.6
10.7
268
1696
T86.8
ICD-10 Finland
Failure and rejection of other transplanted organs and tissues
21.5
10.7
15
7
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
1.8
10.7
168
927
M31.9
ICD-10 Finland
Necrotizing vasculopathy, unspecified
7.5
10.6
24
32
R2110
NOMESCO Finland
Giving the first information
1.6
10.6
245
1518
304
Kela drug reimbursment
Dornase alfa
60.1
10.6
12
*
R05CB13
ATC
dornase alfa (desoxyribonuclease); inhalant
60.1
10.6
12
*
R03AC19
ATC
olodaterol; inhalant
4.5
10.6
36
80
A01AB04
ATC
amphotericin B; local oral
1.7
10.6
225
1363
ZXA05
NOMESCO Finland
Left side
1.3
10.6
1201
9965
J12.9
ICD-10 Finland
Viral pneumonia, unspecified
4.6
10.6
35
76
N07BA03
ATC
varenicline; oral
1.9
10.5
153
823
J10.0
ICD-10 Finland
Influenza with pneumonia, seasonal influenza virus identified
2.9
10.4
62
217
J99.1*M34.8
ICD-10 Finland
Respiratory disorders in systemic: sclerosis
110.2
10.4
11
*
51701
ICD-8 Finland
Other chronic interstitial pneumonia, Fibrosis interstitialis diffusa pulmonum essentialis (Hamman-Rich)
+∞
10.4
10
*
I20.99
ICD-10 Finland
Angina pectoris, unspecified
1.5
10.4
366
2511
J18.1
ICD-10 Finland
Lobar pneumonia, unspecified
2.8
10.4
66
241
B99
ICD-10 Finland
Other and unspecified infectious diseases
2.2
10.3
104
484
R03BB07
ATC
umeclidinium bromide; inhalant
3.4
10.2
48
143
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.4
10.2
608
4608
UGC02
NOMESCO Finland
Rigid bronchoscopy
7.4
10.2
23
31
J94.8
ICD-10 Finland
Other specified pleural conditions
2.2
10.1
96
432
WX720
NOMESCO Finland
Own respiration
1.8
10.1
161
894
AA3AI
NOMESCO Finland
Cone beam CT of facial bones
3.8
10.0
41
109
L04AA29
ATC
tofacitinib; oral
8.4
10.0
21
25
H04.10
ICD-10 Finland
Dry eye syndrome
1.5
10.0
364
2516
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
1.4
10.0
529
3925
E000003
ATC
NA
1.8
10.0
174
995
J98.2
ICD-10 Finland
Interstitial emphysema
14.6
10.0
16
11
ZX197
NOMESCO Finland
NA
14.6
10.0
16
11
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
2.1
10.0
115
566
6BA02
NOMESCO Finland
NA
7.2
10.0
23
32
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
2.2
9.9
98
451
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.2
9.9
1676
14527
D72.1
ICD-10 Finland
Eosinophilia
5.8
9.9
27
47
A41.9
ICD-10 Finland
Sepsis, unspecified
1.7
9.9
184
1073
L04AB06
ATC
golimumab; parenteral
4.7
9.9
32
68
TK800
NOMESCO Finland
Hemodialysis
2.1
9.9
103
486
H03AA01
ATC
levothyroxine sodium; systemic
1.3
9.9
895
7207
B01AC04
ATC
clopidogrel; oral
1.3
9.8
856
6856
51709
ICD-8 Finland
Other chronic interstitial pneumonia, Unspecified
12.2
9.8
17
14
J12.1
ICD-10 Finland
Respiratory syncytial virus pneumonia
5.0
9.8
30
60
S18
ICPC
Laceration/cut
1.2
9.8
1897
16669
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.4
9.8
605
4610
J18.0
ICD-10 Finland
Bronchopneumonia, unspecified
2.4
9.7
80
338
D07BA04
ATC
hydrocortisone and antiseptics; topical
1.5
9.7
359
2492
SPAT1059
SPAT
Spirometry at the office
1.7
9.7
216
1327
J37.0
ICD-10 Finland
Chronic laryngitis
2.0
9.7
128
663
M07.3*L40.5
ICD-10 Finland
Other psoriatic arthropathies
2.4
9.7
79
330
C34.3
ICD-10 Finland
Malignant neoplasm: Lower lobe, bronchus or lung
2.6
9.7
67
259
B59
ICD-10 Finland
Pneumocystosis
13.4
9.6
16
12
J01FA01
ATC
erythromycin; systemic
1.4
9.6
437
3154
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
2.3
9.6
90
403
H26.3
ICD-10 Finland
Drug-induced cataract
4.1
9.6
36
89
XX7LW
NOMESCO Finland
NA
7.8
9.6
21
27
L04AB05
ATC
certolizumab pegol; parenteral
6.8
9.6
23
34
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
2.4
9.6
79
335
GD5CD
NOMESCO Finland
Thorax and upper abdomen combined very extensive CT examination of
3.7
9.6
40
109
D80.3
ICD-10 Finland
Selective deficiency of immunoglobulin G [IgG] subclasses
11.4
9.5
17
15
R03AL03
ATC
vilanterol and umeclidinium bromide; inhalant
2.6
9.5
68
265
JN3AD
NOMESCO Finland
Abdominal CT examination
1.5
9.5
325
2219
L01CB
ATC
Podophyllotoxin derivatives
6.0
9.5
25
42
M06
ICD-10 Finland
Other rheumatoid arthritis
3.8
9.5
38
100
A15.0
ICD-10 Finland
Tuberculosis of lung, confirmed by sputum microscopy with or without culture
6.6
9.4
23
35
FXE00
NOMESCO Finland
Use of ECLA
30.0
9.4
12
*
J70.4
ICD-10 Finland
Drug-induced interstitial lung disorders, unspecified
30.0
9.4
12
*
E84.8
ICD-10 Finland
Cystic fibrosis with other manifestations
+∞
9.4
9
*
G30.1
ICD-10 Finland
Alzheimer disease with late onset
0.6
9.3
126
2126
F17.29
ICD-10 Finland
Addiction caused by tobacco UNS
2.5
9.3
71
289
X59
ICD-10 Finland
Exposure to unspecified factor
1.3
9.3
702
5510
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
2.4
9.3
74
308
M80.0
ICD-10 Finland
Postmenopausal osteoporosis with pathological fracture
2.2
9.3
88
398
M01AB55
ATC
diclofenac, combinations; oral
1.5
9.3
306
2074
XX4AW
NOMESCO Finland
NA
10.7
9.3
17
16
307
Kela drug reimbursment
Tacrine, donepezil, rivastigmine, galantamine and other major and expensive drugs used to treat Alzheimer's disease
0.5
9.3
83
1563
L40.5
ICD-10 Finland
Arthropathic psoriasis
2.6
9.2
66
257
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.5
9.2
321
2201
C08CA05
ATC
nifedipine; systemic
1.5
9.2
331
2284
A40.3
ICD-10 Finland
Sepsis due to Streptococcus pneumoniae
3.3
9.2
44
134
NDL52
NOMESCO Finland
Tenosynovectomy of hand
3.9
9.2
36
93
L95
ICPC
Osteoporosis
1.9
9.2
130
692
K23.8*B37.8
ICD-10 Finland
Esophagitis caused by candidiasis
3.6
9.2
39
108
N06AX11
ATC
mirtazapine; oral
1.2
9.2
1251
10579
A06AC01
ATC
ispaghula (psylla seeds); oral
1.3
9.0
1047
8691
A02BA03
ATC
famotidine; systemic
1.6
9.0
201
1239
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
1.6
9.0
225
1428
XX1AW
NOMESCO Finland
Written report from X-ray examination without contrast peformed elsewhere
3.9
9.0
35
90
A04
ICPC
Weakness/tiredness general
1.4
9.0
528
3987
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
1.7
9.0
168
983
J31.0
ICD-10 Finland
Chronic rhinitis
1.6
9.0
256
1678
L03
ICPC
Low back symptom/complaint
1.3
9.0
899
7329
I25.2
ICD-10 Finland
Old myocardial infarction
1.4
8.9
411
2975
P01AB01
ATC
metronidazole; oral, rectal
1.2
8.9
1496
12933
XA421
NOMESCO Finland
Nocturnal polygraphy
5.2
8.9
26
50
N18.8
ICD-10 Finland
Other chronic renal failure
1.8
8.9
151
858
132
Kela drug reimbursment
Sarcoidosis
3.3
8.9
42
127
M80.9
ICD-10 Finland
Unspecified osteoporosis with pathological fracture
2.1
8.9
93
442
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.5
8.8
286
1928
R04.0
ICD-10 Finland
Epistaxis
1.5
8.8
349
2453
R03AL08
ATC
vilanterol, umeclidinium bromide and fluticasone furoate; inhalant
2.4
8.8
69
286
RS221
NOMESCO Finland
NA
2.5
8.8
65
261
WX730
NOMESCO Finland
Conventional respirator
2.3
8.8
77
337
5010A
ICD-9 Finland
Asbestosis[ASBESTOSIS]
10.7
8.8
16
15
T88.7
ICD-10 Finland
Unspecified adverse effect of drug or medicament
2.5
8.8
64
255
NC1AA
NOMESCO Finland
Elbow X-ray examination without contrast
2.0
8.7
108
548
D07BC01
ATC
betamethasone and antiseptics; topical
1.4
8.7
495
3721
E84.1
ICD-10 Finland
Cystic fibrosis with intestinal manifestations
50.1
8.7
10
*
FNA01
NOMESCO Finland
Anastomosis to coronary artery from internal mammary artery, one distal anastamosis
1.5
8.7
275
1846
ZX140
NOMESCO Finland
Intra articular
3.4
8.6
40
119
EP1AE
NOMESCO Finland
Neck ultrasound examination
1.6
8.6
226
1449
-1
NOMESCO Finland
NA
1.2
8.6
1120
9411
RK250
NOMESCO Finland
NA
3.7
8.6
35
94
J18.8
ICD-10 Finland
Other pneumonia, organism unspecified
3.7
8.6
35
94
AA1AD
NOMESCO Finland
CT of head and brain
1.2
8.6
1124
9456
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
1.7
8.6
166
982
S32.0
ICD-10 Finland
Fracture of lumbar vertebra
1.8
8.6
139
779
TNG11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in knee
3.3
8.6
40
120
M35.3
ICD-10 Finland
Polymyalgia rheumatica
1.6
8.5
196
1217
293
Kela drug reimbursment
Baricitinib
9.0
8.5
17
19
XF622
NOMESCO Finland
Measurement of minute volume of heart
4.9
8.5
26
53
J67.8
ICD-10 Finland
Hypersensitivity pneumonitis due to other organic dusts
27.5
8.5
11
*
J01XB01
ATC
colistin; inhalant, parenteral
20.0
8.5
12
6
ZX121
NOMESCO Finland
Central venous catheter
5.1
8.4
25
49
L04AA11
ATC
[U] etanercept; parenteral
5.1
8.4
25
49
R06AX27
ATC
desloratadine; oral
1.3
8.4
792
6400
RS220
NOMESCO Finland
NA
2.6
8.4
58
223
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
1.8
8.4
134
746
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.4
8.4
444
3292
C81.9
ICD-10 Finland
Hodgkin lymphoma, unspecified
6.0
8.4
22
37
D02AE01
ATC
carbamide; topical
1.5
8.4
259
1730
4038
NOMESCO Finland
NA
90.2
8.4
9
*
XF404
NOMESCO Finland
Ambulatory ECG
1.4
8.4
429
3164
5168X
ICD-9 Finland
Other alveolar and parietoalveolar pneumopathy, Other specified alveolar and parietoalveolar pneumopathies
+∞
8.3
8
*
Z95.1
ICD-10 Finland
Presence of aortocoronary bypass graft
1.5
8.3
253
1683
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
1.8
8.3
129
712
R63.4
ICD-10 Finland
Abnormal weight loss
1.7
8.3
155
910
RK310
NOMESCO Finland
NA
9.4
8.3
16
17
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.2
8.2
1162
9844
UDC00
NOMESCO Finland
Ear microscopy
1.5
8.2
293
2017
M02AA07
ATC
piroxicam; topical
1.2
8.2
1611
14117
R60.0
ICD-10 Finland
Localized oedema
1.4
8.1
493
3740
I21.49
ICD-10 Finland
Acute subendocardial infarction unspecified coronary artery status
1.5
8.1
308
2151
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
3.0
8.1
43
142
R95
ICPC
Chron obstructive pulmonary disease
1.8
8.1
139
795
R06.8
ICD-10 Finland
Other and unspecified abnormalities of breathing
2.4
8.1
63
260
NHG76
NOMESCO Finland
Arthroplasty of other tarsometatarsal joint
2.4
8.1
67
287
J99.1*M32.1
ICD-10 Finland
Respiratory disorders in systemic: lupus erythematosus
33.4
8.1
10
*
3006
Kela drug reimbursment
Baricitinib
8.1
8.1
17
21
FXF00
NOMESCO Finland
Decannulation after ECHLA or ECLA
17.2
8.1
12
7
C02KX04
ATC
macitentan; oral
11.7
8.1
14
12
ZX100
NOMESCO Finland
Oral
2.3
8.0
72
320
D07AA02
ATC
hydrocortisone; topical
1.4
8.0
477
3608
M06.8
ICD-10 Finland
Other specified rheumatoid arthritis
3.3
8.0
38
116
TGW99
NOMESCO Finland
Other minor procedure in thoracic surgery
5.0
8.0
24
48
H19.3*M35.0
ICD-10 Finland
Keratoconjunctivitis sicca
5.2
8.0
23
44
D20
ICPC
Mouth/tongue/lip symptom/complaint
1.7
7.9
158
943
NK5AT
NOMESCO Finland
Joint injection with ultrasound guidance not elsewhere classified
3.7
7.9
32
86
TNG10
NOMESCO Finland
Puncture of knee
2.7
7.9
52
197
N06AA09
ATC
amitriptyline; systemic
1.4
7.9
403
2976
XG467
NOMESCO Finland
Nocturnal CO2 monitoring
7.7
7.9
17
22
EB1CI
NOMESCO Finland
Cone beam imaging of teeth and jaws (3-4 quarters)
3.4
7.8
35
102
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
4.5
7.8
26
58
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
1.9
7.8
107
566
TFP20
NOMESCO Finland
Cardiodefibrillation
1.4
7.8
363
2636
L04AA37
ATC
baricitinib; oral
8.4
7.8
16
19
A91
ICPC
Abnormal result investigation NOS
1.6
7.8
174
1076
M01AH02
ATC
rofecoxib; oral
1.3
7.8
574
4492
5110B
ICD-9 Finland
Pleurisy, Without mention of effusion or current tuberculosis[PLEURA-ADHEESIOT]
4.8
7.7
24
50
R76.0
ICD-10 Finland
Raised antibody titre
6.3
7.7
19
30
NDG74
NOMESCO Finland
Fusion of first IP joint
5.5
7.7
21
38
C61
ICD-10 Finland
Malignant neoplasm of prostate
0.7
7.6
345
4603
D07AD01
ATC
clobetasol; topical
1.3
7.6
582
4573
R03BB06
ATC
glycopyrronium bromide; inhalant
3.5
7.6
33
94
SPAT1249
SPAT
Treatment-related counselling outside office
1.2
7.6
1632
14398
3AC01
NOMESCO Finland
NA
2.6
7.6
51
196
D83.0
ICD-10 Finland
Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
18.4
7.6
11
6
C02KX01
ATC
bosentan; oral
11.8
7.6
13
11
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.4
7.5
354
2576
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
0.7
7.5
328
4403
5823
FHL
Lung avobiopsy and wedge resection
8.8
7.5
15
17
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.4
7.5
428
3218
R03BB05
ATC
aclidinium bromide; inhalant
4.3
7.5
26
61
I84.1
ICD-10 Finland
Internal hemorrhoids with other complications
1.9
7.5
105
563
HA1AA
NOMESCO Finland
X-ray mammography
1.5
7.5
227
1512
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.4
7.5
427
3213
B01AB04
ATC
dalteparin; parenteral
1.5
7.5
216
1422
XX1VW
NOMESCO Finland
Written report from radiologist
3.2
7.4
36
112
K52.88
ICD-10 Finland
Other specified noninfective gastroenteritis and colitis
2.0
7.4
90
457
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
1.7
7.4
158
965
ZX114
NOMESCO Finland
Intramuscular
2.3
7.4
65
288
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
1.6
7.4
184
1169
S22.3
ICD-10 Finland
Fracture of rib
1.5
7.4
274
1908
F2682
NOMESCO Finland
NA
7.6
7.4
16
21
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.2
7.4
1028
8693
R06AX22
ATC
ebastine; oral
1.3
7.3
527
4107
R59.1
ICD-10 Finland
Generalized enlarged lymph nodes
2.4
7.3
59
251
GCA18
NOMESCO Finland
Bronchoscopic dilatation of bronchus
+∞
7.3
7
*
M05.3
ICD-10 Finland
Rheumatoid arthritis with involvement of other organs and systems
9.4
7.3
14
15
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.2
7.2
918
7680
C08CA02
ATC
felodipine; oral
1.3
7.2
467
3580
A07EC02
ATC
mesalazine; oral, rectal
1.6
7.2
184
1174
71239
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Arthritis rheumatoides NUD
2.9
7.2
42
147
WX723
NOMESCO Finland
CPAP therapy
1.8
7.2
114
635
SBA00
NOMESCO Finland
Microbiological examinations
1.9
7.2
94
489
7102A
ICD-9 Finland
Diffuse diseases of connective tissue, Sicca syndrome[SYNDROMA SICCUM PRIMARIUM]
15.7
7.2
11
7
T90
ICPC
Diabetes non-insulin dependent
1.2
7.2
1053
8940
R53
ICD-10 Finland
Malaise and fatigue
1.2
7.2
852
7073
J01DA06
ATC
[U] cefuroxime; systemic
1.3
7.2
543
4257
Z71.8
ICD-10 Finland
Other specified counselling
1.2
7.2
846
7016
NA1BA
NOMESCO Finland
Cervical spine extensive X-ray examination without contrast
2.9
7.2
42
148
EB1JA
NOMESCO Finland
Double panorama tomography of teeth and jaws or similar X-ray examination
3.1
7.2
37
121
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
1.6
7.2
177
1123
L17
ICPC
Foot/toe symptom/complaint
1.2
7.2
1005
8497
J93.9
ICD-10 Finland
Pneumothorax, unspecified
3.5
7.2
31
89
I50
ICD-10 Finland
Heart failure
1.6
7.1
169
1061
SBA10
NOMESCO Finland
Measurement of excretion of saliva
2.7
7.1
46
172
S29
ICPC
Skin symptom/complaint other
1.3
7.1
672
5432
M48.0
ICD-10 Finland
Spinal stenosis
1.3
7.1
570
4510
K07
ICPC
Swollen ankles/oedema
1.5
7.1
197
1288
R96
ICPC
Asthma
1.4
7.1
323
2338
F03
ICD-10 Finland
Unspecified dementia
0.6
7.1
88
1511
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
2.2
7.1
68
314
L27.0
ICD-10 Finland
Generalized skin eruption due to drugs and medicaments
2.5
7.1
50
198
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
1.6
7.0
193
1256
8041/3-C34.3
ICD-O-3
Small cell carcinoma, NOS, of lower lobe, lung
8.8
7.0
14
16
K29.7
ICD-10 Finland
Gastritis, unspecified
1.7
7.0
148
901
3A064
NOMESCO Finland
NA
3.7
7.0
28
75
C03EB01
ATC
furosemide and potassium-sparing agents; systemic
1.5
7.0
217
1451
L57.0
ICD-10 Finland
Actinic keratosis
1.3
7.0
486
3768
J01DA08
ATC
[U] cefaclor; oral
1.4
7.0
286
2030
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.2
7.0
1008
8549
R13
ICD-10 Finland
Dysphagia
1.4
7.0
270
1894
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
1.6
7.0
186
1205
M60.9
ICD-10 Finland
Myositis, unspecified
3.6
6.9
29
81
J20.5
ICD-10 Finland
Acute bronchitis due to respiratory syncytial virus
3.8
6.9
27
71
SPAT1060
SPAT
Administration of oxygen
3.7
6.9
28
76
J32.4
ICD-10 Finland
Chronic pansinusitis
2.5
6.9
52
211
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
1.7
6.9
121
699
B37.0
ICD-10 Finland
Candidal stomatitis
2.6
6.9
46
177
M10
ICD-10 Finland
Gout
1.5
6.9
205
1360
SPAT1310
SPAT
Counselling related to known health issue
1.2
6.9
1300
11318
N06DA03
ATC
rivastigmine; oral, transdermal
0.5
6.9
70
1267
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
1.9
6.9
89
463
N06DA02
ATC
donepezil; oral
0.6
6.8
129
2013
WX204
NOMESCO Finland
Axillary plexus blockaced
1.8
6.8
109
611
XG480
NOMESCO Finland
Histamine provocation of respiratroy tract
2.5
6.8
49
196
I35.0
ICD-10 Finland
Aortic (valve) stenosis
1.4
6.8
325
2373
WW500
NOMESCO Finland
Blood transfusion
1.6
6.8
172
1098
A06AD11
ATC
lactulose; oral
1.3
6.8
708
5787
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.2
6.8
1315
11468
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
1.6
6.8
167
1059
3005
Kela drug reimbursment
Tofacitinib
6.7
6.8
16
24
J86.9
ICD-10 Finland
Pyothorax without fistula
2.5
6.8
49
197
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
2.7
6.8
44
165
602
Kela drug reimbursment
Children's severe malnutrition
10.9
6.8
12
11
B25.8
ICD-10 Finland
Other cytomegaloviral diseases
5.0
6.8
20
40
D86.8
ICD-10 Finland
Sarcoidosis of other and combined sites
3.4
6.8
30
88
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
1.8
6.8
108
603
L01BB01
ATC
NA
5.3
6.8
19
36
C01AA05
ATC
digoxin; systemic
1.3
6.7
459
3546
J70.1
ICD-10 Finland
Chronic and other pulmonary manifestations due to radiation
16.7
6.7
10
6
207
Kela drug reimbursment
Chronic arrhythmias
1.2
6.7
764
6308
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
2.2
6.7
63
288
M80.8
ICD-10 Finland
Other osteoporosis with pathological fracture
3.5
6.7
29
84
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
2.1
6.7
72
349
M01AE03
ATC
ketoprofen; systemic, rectal
1.2
6.6
1645
14654
FN1YT
NOMESCO Finland
Percutaneous insertion of coronary artery stent
1.4
6.6
295
2127
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
1.8
6.6
111
633
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
1.6
6.6
170
1093
J43.1
ICD-10 Finland
Panlobular emphysema
7.8
6.6
14
18
SAA02
NOMESCO Finland
Basic examination of mouth
1.2
6.6
2308
21137
A02BA04
ATC
nizatidine; systemic
1.4
6.6
356
2656
F17.20
ICD-10 Finland
Addiction relationship caused by tobacco addiction relationship currently independent
3.4
6.6
29
85
-44
ICPC
Preventive immunization/medic
1.4
6.6
369
2771
J70.3
ICD-10 Finland
Chronic drug-induced interstitial lung disorders
12.2
6.6
11
9
Y88.3
ICD-10 Finland
Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.8
6.6
114
657
XJC00
NOMESCO Finland
Oesophageal manometry
4.0
6.6
24
60
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
2.3
6.6
54
233
B01AF02
ATC
apixaban; oral
1.3
6.5
473
3687
S02CA02
ATC
flumetasone and antiinfectives; otic
1.5
6.5
217
1480
D11
ICPC
Diarrhoea
1.4
6.5
324
2387
DHA10
NOMESCO Finland
Biopsy of cavity of nose
2.8
6.5
38
135
A11
ICPC
Chest pain NOS
1.4
6.5
301
2189
WVA20
NOMESCO Finland
Medicine administration
1.9
6.5
94
510
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
1.2
6.5
1623
14471
TEA00
NOMESCO Finland
Biopsy of lip
2.8
6.5
39
142
E13.9
ICD-10 Finland
Other specified diabetes mellitus, without complications
2.6
6.4
43
166
M01CC01
ATC
penicillamine; oral
5.7
6.4
17
30
UGC08
NOMESCO Finland
Rigid bronchoscopy with biopsy of lung
69.9
6.4
7
*
N06DX01
ATC
memantine; oral
0.7
6.4
166
2429
SAA01
NOMESCO Finland
Simple examination of mouth
1.2
6.4
2630
24359
NXL00
NOMESCO Finland
Biopsy of muscle
4.2
6.4
22
52
J17.3
ICD-10 Finland
Pneumonia in parasitic diseases
14.3
6.4
10
7
R05FA02
ATC
opium derivatives and expectorants; systemic
1.2
6.4
1628
14531
UJD02
NOMESCO Finland
Gastroscopy
1.5
6.4
208
1410
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
2.3
6.4
55
242
D07CC01
ATC
betamethasone and antibiotics; topical
1.3
6.4
474
3709
I26
ICD-10 Finland
Pulmonary embolism
2.6
6.4
42
161
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
1.3
6.3
451
3507
D70.89
ICD-10 Finland
Neutropenic splenomegaly
2.4
6.3
47
193
L08
ICPC
Shoulder symptom/complaint
1.2
6.3
724
5981
J92
ICD-10 Finland
Pleural plaque
6.5
6.3
15
23
L03AA02
ATC
filgrastim; parenteral
1.8
6.3
106
604
I20.09
ICD-10 Finland
Unstable angina
1.4
6.3
285
2063
4859X
ICD-9 Finland
Bronchopneumonia, organism unspecified[PNEUMONIA NUD]
1.8
6.3
97
540
R01AD01
ATC
beclometasone; nasal
1.3
6.3
517
4101
XG430
NOMESCO Finland
Spiroegometry
11.0
6.3
11
10
49099
ICD-8 Finland
Bronchitis, unspecified
2.5
6.3
45
180
S22.2
ICD-10 Finland
Fracture of sternum
3.1
6.3
32
105
L28
ICPC
Limited function/disability (L)
1.2
6.3
725
5996
M33
ICD-10 Finland
Dermatopolymyositis
+∞
6.2
6
*
6BB16
NOMESCO Finland
NA
+∞
6.2
6
*
S01GX01
ATC
cromoglicic acid; ophthalmic
1.3
6.2
560
4495
XV5WT
NOMESCO Finland
NA
26.7
6.2
8
*
J01CE02
ATC
phenoxymethylpenicillin; oral
1.2
6.2
2774
25831
A31.0
ICD-10 Finland
Pulmonary mycobacterial infection
4.3
6.2
21
49
UJF14
NOMESCO Finland
Enteroscopy of ileoanal anastomosis
4.3
6.2
21
49
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.2
6.2
994
8507
J98.6
ICD-10 Finland
Disorders of diaphragm
3.4
6.2
27
79
K76.9
ICD-10 Finland
Liver disease, unspecified
2.2
6.2
56
251
201
Kela drug reimbursment
Chronic cardiac insufficiency
1.4
6.2
261
1866
C34.32
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung adenocarcinoma
2.5
6.2
44
175
K29.3
ICD-10 Finland
Chronic superficial gastritis
1.6
6.1
139
865
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
2.1
6.1
64
308
KEC01
NOMESCO Finland
Percutaneous endoscopic radical prostatectomy
0.4
6.1
22
565
R03AC18
ATC
indacaterol; inhalant
2.5
6.1
45
184
N19
ICD-10 Finland
Unspecified kidney failure
1.5
6.1
169
1106
ECB20
NOMESCO Finland
Oral alveoplasty
2.5
6.1
42
166
B34.9
ICD-10 Finland
Viral infection, unspecified
1.9
6.1
77
400
WNF00
NOMESCO Finland
Infection source and contact determination
3.2
6.1
29
91
JF1CG
NOMESCO Finland
Extensive MRI of small bowel
4.0
6.1
22
55
P70
ICPC
Dementia
0.4
6.1
26
621
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
2.1
6.1
63
302
E66.01
ICD-10 Finland
Obesity due to excess calories
1.5
6.0
201
1370
J32.9
ICD-10 Finland
Chronic sinusitis, unspecified
2.7
6.0
37
137
J15.1
ICD-10 Finland
Pneumonia due to Pseudomonas
6.7
6.0
14
21
1243
FHL
Bronchoscopy and other therapeutic procedure
6.7
6.0
14
21
R04
ICPC
Breathing problem other
1.7
6.0
123
746

Mortality – FinRegistry

Association

Association between endpoint ILD_ENDPOINTS and mortality.

Females

Parameter HR [95% CI] p-value
ILD_ENDPOINTS 3.129 [2.83, 3.46] < 0.001
Birth year 0.998 [0.99, 1.01] 0.654

During the follow-up period (1.1.1998 — 31.12.2019), 5154 out of 10663 females with ILD_ENDPOINTS died.

Males

Parameter HR [95% CI] p-value
ILD_ENDPOINTS 3.447 [3.02, 3.93] < 0.001
Birth year 0.984 [0.98, 0.99] < 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 7550 out of 13773 males with ILD_ENDPOINTS died.

Mortality risk

Mortality risk for people of age

years, who have ILD_ENDPOINTS.

N-year risk Females Males
1 0.278% 0.578%
5 2.021% 3.367%
10 5.217% 8.484%
15 9.234% 15.625%
20 16.058% 25.4%

Relationships between endpoints

Index endpoint: ILD_ENDPOINTS – Interstitial lung disease endpoints

GWS hits: 15

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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