Cardiomyopathies, Secondary/extrinsic

I9_CARDMSEC

cardiomyopathy: A disease of the heart muscle or myocardium proper. Cardiomyopathies may be classified as either primary or secondary, on the basis of etiology, or on the pathophysiology of the lesion: hypertrophic, dilated, or restrictive.

Suggest a new description

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 I42.6, I42.7#
  • Hospital discharge: ICD-9 4258A
  • Cause of death: ICD-10 I42.6, I42.7#
  • Cause of death: ICD-9 4258A

2 out of 7 registries used, show all original rules.

224

4. Check minimum number of events

None

224

5. Include endpoints

None

224

6. Filter based on genotype QC (FinnGen only)

224

Control definitions (FinnGen only)

Control exclude
I9_OTHHEART

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 4781 746 3926
Only index persons 2094 381 1713
Unadjusted period prevalence (%)
Whole population 0.10 0.02 0.11
Only index persons 0.06 0.01 0.07
Median age at first event (years)
Whole population 56.51 59.10 55.87
Only index persons 58.60 60.45 58.19

-FinnGen-

Key figures

All Female Male
Number of individuals 224 65 159
Unadjusted period prevalence (%) 0.06 0.02 0.07
Median age at first event (years) 60.19 55.59 62.07

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
200
Matched controls
1998
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
I42.6
ICD-10 Finland
Alcoholic cardiomyopathy
+∞
156.5
129
*
I50.9
ICD-10 Finland
Heart failure, unspecified
319.7
94.4
89
5
I42.0
ICD-10 Finland
Dilated cardiomyopathy
+∞
88.2
78
*
201
Kela drug reimbursment
Chronic cardiac insufficiency
119.6
77.2
80
11
I42.7
ICD-10 Finland
Cardiomyopathy due to drugs and other external agents
+∞
71.1
64
*
I48
ICD-10 Finland
Atrial fibrillation and flutter
69.3
58.7
66
14
I50.1
ICD-10 Finland
Left ventricular failure
+∞
54.7
50
*
I50.0
ICD-10 Finland
Congestive heart failure
330.4
51.6
50
*
C01AA05
ATC
digoxin; systemic
55.0
50.4
59
15
C03CA01
ATC
furosemide; systemic
10.9
49.0
118
233
C03DA01
ATC
spironolactone; oral
18.4
46.0
75
63
I42.9
ICD-10 Finland
Cardiomyopathy, unspecified
+∞
43.3
40
*
207
Kela drug reimbursment
Chronic arrhythmias
460.1
39.5
38
*
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
112.7
35.0
37
*
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
9.7
31.3
70
105
B01AA03
ATC
warfarin; systemic
9.6
29.7
66
97
C07AB07
ATC
bisoprolol; oral
5.7
29.3
127
466
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
+∞
27.7
26
*
I47.2
ICD-10 Finland
Ventricular tachycardia
+∞
23.4
22
*
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
258.0
23.1
23
*
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
258.0
23.1
23
*
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
+∞
22.3
21
*
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
5.8
21.9
72
177
K78
ICPC
Atrial fibrillation/flutter
30.9
20.6
27
10
C09DX04
ATC
valsartan and sacubitril; oral
+∞
20.1
19
*
289
Kela drug reimbursment
Combination product containing sacubitril and valsartan
+∞
20.1
19
*
C09AA05
ATC
ramipril; oral
4.5
19.4
85
280
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
5.9
19.4
60
135
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
8.1
19.1
45
69
C01BD01
ATC
amiodarone; systemic
208.5
18.9
19
*
TFP20
NOMESCO Finland
Cardiodefibrillation
73.5
18.1
20
*
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
9.9
17.1
35
42
I34.09
ICD-10 Finland
Mitral (valve) insufficiency
+∞
15.8
15
*
XF400
NOMESCO Finland
ECG with 12 standard connections
4.8
15.8
58
155
381
Kela drug reimbursment
Combination product containing sacubitril and valsartan
+∞
14.8
14
*
K70.0
ICD-10 Finland
Alcoholic fatty liver
24.5
14.5
20
9
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.9
14.3
50
126
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
12.2
13.4
24
22
I44.7
ICD-10 Finland
Left bundle-branch block, unspecified
+∞
12.6
12
*
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
138.1
12.6
13
*
GD1LA
NOMESCO Finland
GD
138.1
12.6
13
*
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
9.2
12.5
26
32
F10.40
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without seizures
24.6
11.8
16
7
AN1
HP
Coronary angiography
4.7
11.1
39
97
P15
ICPC
Chronic alcohol abuse
11.5
10.5
19
18
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
115.7
10.5
11
*
PH1AC
NOMESCO Finland
Flebography of over extremity with X-ray
115.7
10.5
11
*
N07BB01
ATC
disulfiram; oral
7.3
9.8
23
35
F10.31
ICD-10 Finland
Withdrawal symptoms caused by alcohol with seizures
18.6
9.5
14
8
A12BA01
ATC
potassium chloride; oral
10.3
9.5
18
19
FPG96
NOMESCO Finland
Other implantation of permanent cardioverter-defibrillator
+∞
9.4
9
*
I46.0
ICD-10 Finland
Cardiac arrest with successful resuscitation
+∞
9.4
9
*
4273A
ICD-9 Finland
Cardiac dysrhythmias, Atrial fibrillation and flutter
+∞
9.4
9
*
A98
ICPC
Health maint/preventive medicine
0.4
9.2
124
1634
K77
ICPC
Heart failure
38.5
9.1
11
*
Z2221
NOMESCO Finland
Medical doctor
2.9
9.0
62
264
F10.26
ICD-10 Finland
Alcohol dependence periodic alcoholism
14.9
8.8
14
10
F10.2
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Dependence syndrome
14.9
8.8
14
10
R56.8
ICD-10 Finland
Other and unspecified convulsions
7.0
8.7
21
33
F10.20
ICD-10 Finland
Alcohol dependence currently independent
12.3
8.7
15
13
I42.2
ICD-10 Finland
Other hypertrophic cardiomyopathy
+∞
8.4
8
*
I48.1
ICD-10 Finland
Persistent atrial fibrillation
+∞
8.4
8
*
FPG32
NOMESCO Finland
Implantation of cardioverter-defibrillator with atrial and ventricular electrodes
+∞
8.4
8
*
FPE96
NOMESCO Finland
Other implantation or replacement of transvenous cardiac pacemaker
+∞
8.4
8
*
4258A
ICD-9 Finland
Cardiomyopathy in other diseases classified elsewhere
+∞
8.4
8
*
I34.00
ICD-10 Finland
Mitral (valve) incompetence NOS or of specified cause, except rheumatic
+∞
8.4
8
*
FPE20
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with atrial and ventricular electrodes
+∞
8.4
8
*
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
12.4
8.2
14
12
F10.21
ICD-10 Finland
Alcohol dependence currently abstinent, but staying in restrictive environment
23.1
8.1
11
5
TPH07
NOMESCO Finland
Cathetrisation of artery
4.3
8.1
30
79
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.7
8.1
64
295
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
9.0
8.0
16
19
F10.25
ICD-10 Finland
Alcohol dependence continuous use
10.0
7.9
15
16
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.4
7.8
90
509
F10.24
ICD-10 Finland
Alcohol depence active use
12.5
7.7
13
11
ZX120
NOMESCO Finland
Intravenous
4.2
7.5
28
74
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.2
7.5
41
148
C07AB02
ATC
metoprolol; systemic
2.9
7.4
49
202
K70.3
ICD-10 Finland
Alcoholic cirrhosis of liver
11.5
7.4
13
12
I42.8
ICD-10 Finland
Other cardiomyopathies
+∞
7.3
7
*
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
+∞
7.3
7
*
1CX08
NOMESCO Finland
NA
+∞
7.3
7
*
N05CF01
ATC
zopiclone; oral
2.4
7.2
75
396
115
Kela drug reimbursment
Breast cancer
5.3
7.2
21
43
I47.1
ICD-10 Finland
Supraventricular tachycardia
31.2
7.2
9
*
Z3231
NOMESCO Finland
Registered nurse
2.5
7.2
62
299
C07AA07
ATC
sotalol; systemic
10.6
7.1
13
13
F10.09
ICD-10 Finland
Alcohol intoxication UNS
10.6
7.1
13
13
F10.0
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Acute intoxication
10.6
7.1
13
13
XF404
NOMESCO Finland
Ambulatory ECG
6.3
7.1
18
31
B01AF02
ATC
apixaban; oral
8.0
7.0
15
20
F10.39
ICD-10 Finland
Withdrawal symptoms caused by alcohol UNS
14.4
7.0
11
8
N05BA02
ATC
chlordiazepoxide; systemic
8.7
6.9
14
17
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
7.6
6.8
15
21
XFE00
NOMESCO Finland
Epicardial ultrasonography
23.4
6.7
9
*
M04AA01
ATC
allopurinol; systemic
3.2
6.7
37
134
L03AA02
ATC
filgrastim; parenteral
6.6
6.6
16
26
N05BA04
ATC
oxazepam; oral
2.6
6.6
54
250
R06.0
ICD-10 Finland
Dyspnoea
2.6
6.5
51
231
T36
ICD-10 Finland
Poisoning by systemic antibiotics
6.3
6.4
16
27
XF640
NOMESCO Finland
NA
11.5
6.4
11
10
I42.1
ICD-10 Finland
Obstructive hypertrophic cardiomyopathy
+∞
6.3
6
*
TFP30
NOMESCO Finland
Cathetric examination for cardiac arrythmia
+∞
6.3
6
*
FPJ24
NOMESCO Finland
Revision of biventricular cardioverter-defibrillator with atrial and ventricular electrodes
+∞
6.3
6
*
I44.2
ICD-10 Finland
Atrioventricular block, complete
+∞
6.3
6
*
2000B
ICD-9 Finland
Lymphosarcoma and reticulosarcoma, Reticulosarcoma[LYMPHOMA MALIGNUM DIFFUSUM]
+∞
6.3
6
*
42792
ICD-8 Finland
Symptomatic heart disease, Fibrillatio auricularis
+∞
6.3
6
*
I50
ICD-10 Finland
Heart failure
27.6
6.3
8
*
K70.4
ICD-10 Finland
Alcoholic hepatic failure
27.6
6.3
8
*
WX892
NOMESCO Finland
Monitored bed care
4.5
6.2
21
51
N05AA02
ATC
levomepromazine; systemic
4.9
6.2
19
42

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3003458) Phosphate [Moles/volume] in Serum or Plasma
59
178
4.14
17.80
7.9
4.5
mmol/l
1.1
1.0
0.82
54
166
(3000991) Gas panel - Venous blood
40
109
4.25
13.63
22.6
7.2
—
—
—
0
0
(3012441) Differential panel - Pleural fluid
14
13
11.42
12.98
1.4
1.4
—
—
—
0
0
(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma
34
97
3.95
10.81
3.3
2.1
ug/l
8.4
4.7
0.50
34
89
(3003396) Base excess in Arterial blood by calculation
44
151
3.38
10.65
17.6
6.5
mmol/l
1.5
1.1
0.30
39
117
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
124
1693
0.40
10.03
4.8
4.4
mmol/l
4.6
4.7
0.52
109
1554
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
129
1728
0.40
9.79
5.5
4.9
mmol/l
2.7
2.8
0.82
115
1577
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
123
1680
0.41
9.78
4.8
4.4
mmol/l
1.3
1.4
1.71
108
1527
(3002032) Base excess in Venous blood by calculation
39
133
3.34
9.49
8.4
2.9
mmol/l
2.4
1.7
0.54
31
101
(3012544) pH of Venous blood
38
134
3.21
8.74
8.4
3.0
—
—
—
0
0
(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay
16
29
5.86
8.63
1.3
1.3
—
—
—
0
0
(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay
16
29
5.86
8.63
1.3
1.3
—
—
—
0
0
(3014007) Fractional oxyhemoglobin in Arterial blood
29
87
3.68
8.55
24.7
8.1
%
93.2
94.2
0.35
29
87
(3006217) Methemoglobin/Hemoglobin.total in Arterial blood
28
86
3.58
7.96
25.4
8.1
%
0.6
0.7
1.12
28
86
(3045788) Cell count panel - Pleural fluid
12
8
15.75
7.80
1.8
1.0
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
30
98
3.38
7.77
1.8
1.4
—
—
—
0
0
(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma
70
361
2.37
7.65
2.8
1.8
mg/l
2.7
3.0
0.63
61
309
(3023368) Bacteria identified in Blood by Culture
82
453
2.28
7.63
7.1
4.0
—
—
—
0
0
(40768806) Pleura Pathology biopsy report
11
15
7.66
7.62
1.6
1.8
—
—
—
0
0
(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood
27
86
3.43
7.26
25.8
8.0
%
1.7
1.5
0.52
27
86
(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma
52
938
0.42
7.08
3.9
4.9
ug/l
1.9
2.7
0.83
42
838
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
124
1627
0.47
7.08
4.7
3.9
mmol/l
1.6
1.3
3.33
109
1473
(3022250) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Lactate to pyruvate reaction
39
158
2.78
6.98
15.2
5.1
u/l
238.6
249.3
0.23
39
149
(40761511) CBC panel - Blood by Automated count
144
1787
0.46
6.90
28.2
11.3
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
40
172
2.61
6.37
2.0
1.7
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
40
172
2.61
6.37
1.9
1.7
—
—
—
0
0
(3020891) Body temperature
19
52
3.90
6.35
8.2
3.6
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
15
34
4.66
6.34
5.1
2.6
u/ml
0.3
0.3
—
9
15
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
125
1613
0.49
6.23
6.5
5.8
mmol/mol
43.2
40.1
1.99
112
1484
(3042936) Bacteria identified in Isolate by Culture
51
251
2.34
6.07
3.8
1.9
—
—
—
0
0
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
133
1675
0.49
6.00
5.2
4.5
mmol/l
6.5
6.0
1.98
120
1519
(3016417) Amylase.pancreatic [Enzymatic activity/volume] in Serum or Plasma
35
149
2.60
5.67
3.3
2.5
u/l
32.7
30.0
0.20
30
127
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
49
245
2.28
5.60
2.4
1.7
—
—
—
0
0
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
20
62
3.44
5.60
8.9
2.2
%
1.5
1.2
0.57
20
62
(3018677) aPTT in Platelet poor plasma by Coagulation assay
47
231
2.31
5.59
5.1
2.0
s
30.8
29.2
1.21
47
226
(1761868) Lipid panel - Serum or Plasma
29
620
0.39
5.57
3.1
2.7
—
—
—
0
0
(3002173) Hemoglobin [Mass/volume] in Arterial blood
31
127
2.67
5.41
23.3
7.2
g/l
125.5
122.2
0.35
31
122
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
41
753
0.44
5.38
3.2
4.3
%
21.5
21.5
0.00
15
386
(3014891) Appearance of Pleural fluid
5
0
+∞
5.22
1.2
0.0
—
—
—
0
0
(3018418) pH of Serum or Plasma
75
463
1.93
4.85
5.9
3.8
ph
7.4
7.4
0.23
13
83
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
133
1640
0.53
4.80
33.4
11.8
ml/min/173m2
79.6
80.2
0.11
123
1332
(36304419) Bacteria [Presence] in Urine
73
449
1.93
4.76
3.2
2.9
—
—
—
0
0
(3001122) Ferritin [Mass/volume] in Serum or Plasma
89
597
1.81
4.36
3.8
2.3
ug/l
197.3
187.9
0.10
82
549
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
14
41
3.58
4.26
1.4
1.4
—
—
—
0
0
(3024891) Influenza virus A+B Ag [Presence] in Specimen
14
41
3.58
4.26
1.1
1.2
—
—
—
0
0
(3030467) Casts [#/volume] in Urine by Automated count
74
472
1.85
4.25
3.2
2.9
e6/l
0.7
0.6
0.20
62
341
(3018405) Lactate [Moles/volume] in Arterial blood
15
47
3.35
4.14
5.4
5.2
mmol/l
2.2
1.3
0.66
15
47
(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma
35
173
2.21
4.07
3.8
3.4
umol/l
16.4
9.1
0.46
28
156
(3032080) INR in Blood by Coagulation assay
88
599
1.77
4.04
19.7
4.7
inr
1.5
1.1
1.72
18
167
(3043409) Potassium [Moles/volume] in Arterial blood
13
38
3.57
3.96
6.1
4.3
mmol/l
4.2
3.8
2.43
13
38
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
23
95
2.58
3.95
1.4
1.3
—
—
—
0
0
(3036782) Glucose [Moles/volume] in Pleural fluid
8
11
7.49
3.89
1.4
1.5
mmol/l
5.3
6.0
—
8
11
(3007853) Bacteria identified in Skin by Aerobe culture
36
185
2.13
3.80
2.9
1.5
—
—
—
0
0
(1616796) Gas panel - Central venous blood
10
25
4.14
3.74
1.9
2.7
—
—
—
0
0
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
142
1680
0.58
3.66
36.1
12.3
mg/l
28.9
25.2
0.74
133
1296
(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma
10
26
3.98
3.56
1.8
1.3
—
—
—
0
0
(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma
31
553
0.49
3.43
2.4
3.0
ug/l
0.6
0.8
0.93
22
375
(40763082) Lactate dehydrogenase [Enzymatic activity/volume] in Pleural fluid by Lactate to pyruvate reaction
7
10
7.18
3.39
1.4
1.9
u/l
241.1
428.8
—
7
10
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
87
615
1.68
3.37
3.7
3.0
—
—
—
0
0
(3002582) Erythrocytes [#/volume] in Urine
75
519
1.67
3.11
3.2
3.1
e6/l
28.5
77.8
1.35
62
388
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
11
34
3.35
3.10
1.5
1.3
—
—
—
0
0
(3022806) Fractional oxyhemoglobin in Capillary blood
8
16
5.14
3.08
1.6
1.9
%
89.0
90.0
—
8
16
(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma
70
478
1.68
3.04
3.1
2.0
u/l
181.6
186.0
0.06
70
450
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
17
69
2.58
3.04
36.9
7.7
—
—
—
0
0
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
47
288
1.80
2.98
3.1
2.8
e6/l
1.1
1.2
0.02
32
167
(3019060) Gas panel - Arterial blood
19
83
2.41
2.93
5.2
3.7
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
68
935
0.61
2.92
2.9
2.7
—
—
—
0
0
(3001604) Monocytes [#/volume] in Blood
106
813
1.58
2.83
7.9
5.6
e9/l
0.6
0.6
1.04
93
700
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
57
376
1.69
2.79
4.1
2.2
—
—
—
0
0
(3019198) Lymphocytes [#/volume] in Blood
107
833
1.54
2.62
8.0
5.6
e9/l
1.7
1.9
1.76
96
742
(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay
9
25
3.71
2.60
1.2
1.2
—
—
—
0
0
(3006315) Basophils [#/volume] in Blood
105
815
1.54
2.60
8.0
5.6
e9/l
0.0
0.0
0.10
93
709
(3044941) Cell count panel - Synovial fluid
8
20
4.11
2.59
1.4
1.4
—
—
—
0
0
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
12
44
2.83
2.59
1.4
1.1
—
—
—
0
0
(3018095) Leukocytes [#/volume] in Urine
81
594
1.57
2.58
3.6
3.6
e6/l
80.9
96.2
0.09
66
414
(3009542) Hematocrit [Volume Fraction] of Blood
129
1515
0.65
2.52
39.9
13.4
%
39.3
40.0
0.64
93
1074
(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method
7
16
4.48
2.49
1.3
1.4
—
—
—
0
0
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
101
783
1.53
2.49
15.9
5.9
mmol/l
1.2
1.2
3.07
85
670
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
9
27
3.43
2.42
2.1
1.7
—
—
—
0
0
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
9
27
3.43
2.42
1.9
1.7
—
—
—
0
0
(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma
6
12
5.10
2.41
2.5
1.8
—
—
—
0
0
(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma
69
495
1.57
2.39
3.5
3.6
u/l
48.1
30.8
1.79
64
479
(40758558) Short blood count panel - Blood
59
408
1.61
2.39
9.8
7.0
—
—
—
0
0
(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection
8
23
3.57
2.29
1.1
1.3
—
—
—
0
0
(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
7
18
3.98
2.27
2.1
1.9
—
—
—
0
0
(3024928) Oxygen saturation in Venous blood
8
24
3.42
2.20
13.1
2.4
—
—
—
0
0
(3013115) Eosinophils [#/volume] in Blood
105
837
1.48
2.19
8.1
5.8
e9/l
0.1
0.2
4.13
93
742
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
48
324
1.61
2.13
8.8
1.8
mg/l
2.3
1.4
0.53
36
261
(3007080) Epstein Barr virus nuclear IgG Ab [Units/volume] in Serum
8
25
3.28
2.11
1.3
1.1
u/ml
278.9
312.1
—
8
15
(3016724) Homocysteine [Moles/volume] in Serum or Plasma
5
10
5.09
2.08
1.8
1.4
umol/l
15.6
13.4
—
5
10
(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection
5
10
5.09
2.08
2.6
1.6
—
—
—
0
0
(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection
5
10
5.09
2.08
2.6
1.6
—
—
—
0
0
(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection
5
10
5.09
2.08
2.6
1.6
—
—
—
0
0
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
127
1472
0.68
2.06
4.8
4.0
mu/l
2.0
1.9
0.34
118
1295
(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection
8
28
2.92
1.88
1.0
1.4
—
—
—
0
0
(3042111) Morphology [Interpretation] in Bone marrow Narrative
7
24
2.98
1.73
1.6
2.2
—
—
—
0
0
(3021788) Differential panel - Synovial fluid
7
24
2.98
1.73
1.3
1.6
—
—
—
0
0
(3027529) Toxoplasma gondii IgM Ab [Units/volume] in Serum
5
13
3.91
1.72
1.2
1.2
—
—
—
0
0
(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum
5
13
3.91
1.72
2.4
2.5
—
—
—
0
0
(3051387) C reactive protein [Mass/volume] in Capillary blood
0
48
0.00
1.72
0.0
3.5
—
23.1
—
0
27
(42870588) Differential panel, method unspecified - Blood
70
537
1.44
1.70
8.1
5.6
—
—
—
0
0
(3021879) Hepatitis B virus core Ab [Presence] in Serum
19
105
1.88
1.69
1.4
1.5
—
—
—
0
0
(3013650) Neutrophils [#/volume] in Blood by Automated count
114
955
1.39
1.68
12.7
9.6
e9/l
4.5
4.1
0.84
102
839
(3028271) Lactate [Moles/volume] in Capillary blood
6
19
3.21
1.67
1.7
1.9
mmol/l
2.0
1.5
—
6
19
(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection
6
19
3.21
1.67
1.0
1.3
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
33
216
1.62
1.66
2.0
1.8
—
—
—
0
0
(21494755) Public health laboratory ask at order entry panel
7
160
0.42
1.61
2.0
1.5
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
67
516
1.43
1.58
4.5
2.2
—
—
—
0
0
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
17
93
1.90
1.56
1.9
1.6
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
96
1138
0.73
1.55
5.3
3.8
—
—
—
0
0
(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay
0
44
0.00
1.53
0.0
2.3
—
—
—
0
0
(3027544) Mycobacterium sp identified in Sputum by Organism specific culture
6
21
2.91
1.51
3.5
3.2
—
—
—
0
0
(3028707) Methadone [Presence] in Urine by Screen method
6
21
2.91
1.51
2.5
1.1
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
48
636
0.69
1.49
5.1
3.4
—
—
—
0
0
(3036481) Cortisol [Moles/volume] in Serum or Plasma
23
141
1.70
1.48
2.6
2.2
nmol/l
425.6
359.4
1.38
23
131
(3050238) Crystals [Presence] in Synovial fluid by Light microscopy
9
38
2.42
1.47
1.0
1.6
—
—
—
0
0
(3048929) Epstein Barr virus Ab [Presence] in Serum
9
39
2.36
1.45
1.2
1.1
—
—
—
0
0
(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection
6
22
2.77
1.44
1.0
1.4
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
32
456
0.65
1.43
3.8
3.0
—
—
—
0
0
(3021589) Normoblasts [#/volume] in Blood
92
760
1.36
1.41
12.3
9.1
e9/l
0.0
0.0
0.15
72
619
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
39
278
1.49
1.37
3.3
3.0
e6/l
1.8
1.4
0.11
23
160
(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability
5
17
2.98
1.36
1.4
1.2
—
—
—
0
0
(3045142) Bone marrow Pathology biopsy report
5
17
2.98
1.36
2.0
1.4
—
—
—
0
0
(3016921) Smith extractable nuclear Ab [Units/volume] in Serum
0
37
0.00
1.35
0.0
1.3
—
3.4
—
0
7
(3006999) Ribonucleoprotein extractable nuclear Ab [Units/volume] in Serum
0
38
0.00
1.35
0.0
1.3
—
2.7
—
0
7
(3009261) Glucose [Presence] in Urine by Test strip
66
813
0.73
1.30
4.3
3.2
estimate
0.0
0.0
0.00
13
135
(3035637) Corticotropin [Mass/volume] in Plasma
5
18
2.82
1.29
1.2
1.3
—
—
—
0
0
(3000764) Benzodiazepines [Presence] in Urine
9
44
2.09
1.28
2.1
1.1
—
—
—
0
0
(3016650) Hepatitis A virus Ab [Presence] in Serum
8
35
2.33
1.28
1.1
1.1
—
—
—
0
0
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
99
1147
0.75
1.27
4.1
3.3
pmol/l
14.9
14.8
0.19
94
998
(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma
41
301
1.44
1.25
4.6
3.0
mmol/l
2.5
2.4
0.33
35
266
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
11
57
1.98
1.19
1.5
2.7
—
—
—
0
0
(3035350) Ketones [Presence] in Urine by Test strip
66
804
0.75
1.19
4.3
3.2
estimate
0.0
0.0
0.00
13
142
(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay
0
34
0.00
1.17
0.0
1.4
—
—
—
0
0
(3019230) Fractional oxyhemoglobin in Venous blood
5
20
2.53
1.15
17.4
2.3
%
64.4
61.7
—
5
20
(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay
0
36
0.00
1.15
0.0
1.1
—
—
—
0
0
(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay
0
36
0.00
1.15
0.0
1.3
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
26
177
1.53
1.14
1.6
1.5
—
—
—
0
0
(3021601) Nitrite [Presence] in Urine by Test strip
66
799
0.75
1.13
5.6
4.5
estimate
0.0
0.0
0.00
13
144
(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma
12
66
1.86
1.11
3.4
3.7
pmol/l
4.3
4.9
0.91
12
52
(3004588) Protein electrophoresis panel - Serum or Plasma
17
105
1.67
1.09
1.5
2.4
—
—
—
0
0
(3023520) Reticulocytes [#/volume] in Blood
19
122
1.61
1.06
4.4
2.5
e9/l
70.9
75.3
0.19
14
92
(3013707) Erythrocyte sedimentation rate by Westergren method
109
1229
0.78
1.06
4.5
3.8
mm/h
19.8
12.0
2.94
103
1121
(3027008) Opiates [Presence] in Urine
9
46
2.00
1.05
2.1
1.1
—
—
—
0
0
(3027944) Amphetamines [Presence] in Urine
9
46
2.00
1.05
2.1
1.2
—
—
—
0
0
(3028300) Cannabinoids [Presence] in Urine
9
46
2.00
1.05
2.1
1.1
—
—
—
0
0
(40758310) Human epididymis protein 4 [Moles/volume] in Serum or Plasma
5
22
2.30
1.04
2.4
1.3
pmol/l
103.8
77.6
—
5
22
(3015377) Calcium [Moles/volume] in Serum or Plasma
64
523
1.31
1.02
5.6
3.5
mmol/l
2.3
2.3
0.75
56
456
(3017143) Hepatitis C virus Ab [Presence] in Serum
24
166
1.50
0.99
1.6
1.6
—
—
—
0
0
(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma
5
23
2.20
0.98
1.2
1.3
ug/l
17.6
16.7
—
5
23
(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing
7
37
1.92
0.95
1.9
1.6
—
—
—
0
0
(3013512) EKG study
38
487
0.74
0.94
7.0
3.3
—
—
—
0
0
(40761535) Cells panel - Urine sediment
19
127
1.54
0.92
5.2
3.0
—
—
—
0
0
(3011288) Drugs identified in Urine by Screen method
6
29
2.10
0.90
1.5
1.3
—
—
—
0
0
(3016879) Cocaine [Presence] in Urine
8
43
1.89
0.88
2.3
1.1
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
53
431
1.30
0.87
3.3
2.9
—
—
—
0
0
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
72
613
1.26
0.83
6.1
2.6
ng/l
36.1
44.6
0.37
61
428
(3052851) Hemolysis interference index of Serum or Plasma
6
34
1.79
0.77
8.7
2.7
—
—
—
0
0
(4010399)
16
108
1.52
0.76
1.5
1.5
—
—
—
0
0
(4035726)
22
160
1.42
0.73
1.6
1.4
—
—
—
0
0
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
10
60
1.70
0.73
1.3
3.1
—
—
—
0
0
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
15
216
0.67
0.73
19.7
5.5
—
—
—
0
0
(3003327) Ova and parasites identified in Stool by Light microscopy
7
39
1.82
0.73
1.0
1.4
—
—
—
0
0
(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method
5
25
2.02
0.73
1.0
1.0
—
—
—
0
0
(3002256) Pathology report gross observation
30
231
1.34
0.72
1.3
1.3
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
35
436
0.77
0.72
1.7
1.3
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
26
196
1.37
0.71
2.3
1.4
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
42
341
1.29
0.71
5.5
4.7
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
16
224
0.69
0.68
1.5
1.5
—
—
—
0
0
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
10
62
1.64
0.66
3.6
1.8
—
—
—
0
0
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
11
165
0.65
0.66
1.6
1.5
—
—
—
0
0
(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum
7
44
1.61
0.65
1.3
1.1
—
—
—
0
0
(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum
5
29
1.74
0.64
1.0
1.1
—
—
—
0
0
(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence
5
29
1.74
0.64
1.0
1.0
—
—
—
0
0
(40768443) Skin Pathology biopsy report
10
63
1.61
0.63
1.0
1.4
—
—
—
0
0
(3017446) Testosterone [Moles/volume] in Serum or Plasma
12
174
0.67
0.62
2.7
2.1
nmol/l
7.4
13.9
2.10
12
157
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
23
175
1.35
0.61
5.5
2.8
—
—
—
0
0
(3000242) Tau protein [Mass/volume] in Cerebral spinal fluid
0
20
0.00
0.60
0.0
1.0
—
257.9
—
0
10
(3042810) Amyloid beta 42 peptide [Mass/volume] in Cerebral spinal fluid
0
20
0.00
0.60
0.0
1.0
—
511.7
—
0
10
(43055225) Phosphorylated tau 181 [Mass/volume] in Cerebral spinal fluid by Immunoassay
0
20
0.00
0.60
0.0
1.1
—
37.1
—
0
10
(3004616) Nuclear Ab [Presence] in Serum
0
21
0.00
0.60
0.0
1.2
—
—
—
0
0
(3039162) Centromere protein B Ab [Units/volume] in Serum
0
21
0.00
0.60
0.0
1.2
—
—
—
0
0
(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain
0
23
0.00
0.58
0.0
1.4
—
—
—
0
0
(3049717) Cytology report of Urine Cyto stain
5
90
0.55
0.57
2.4
3.1
—
—
—
0
0
(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum
8
55
1.47
0.56
1.0
1.0
—
—
—
0
0
(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection
6
37
1.64
0.56
1.8
2.7
—
—
—
0
0
(3029937) Albumin [Presence] in Urine by Test strip
36
432
0.80
0.55
5.4
3.3
estimate
0.0
0.0
0.50
12
140
(1001926) Buprenorphine [Presence] in Urine by Screen method
6
38
1.59
0.54
1.7
1.1
—
—
—
0
0
(44816559) Phosphatidylethanol [Mass/volume] in Blood
6
38
1.59
0.54
2.2
1.5
—
—
—
0
0
(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)
15
108
1.42
0.54
5.3
2.7
ml/min/173m2
53.4
68.0
—
5
43
(40760888) Immunoglobulin light chains.free panel - Serum
6
40
1.51
0.52
1.0
4.7
—
—
—
0
0
(3013826) Glucose [Moles/volume] in Serum or Plasma
104
956
1.16
0.51
13.9
3.9
mmol/l
6.9
6.8
0.32
99
885
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
7
45
1.57
0.49
1.0
1.2
—
—
—
0
0
(3019225) pH of Specimen
12
165
0.71
0.48
7.4
3.7
—
—
—
0
0
(3023024) Carbon dioxide [Partial pressure] in Capillary blood
13
94
1.41
0.47
4.1
2.3
kpa
5.0
5.0
0.03
13
87
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
83
755
1.16
0.46
5.9
3.8
—
—
—
0
0
(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection
5
31
1.63
0.43
1.8
2.7
—
—
—
0
0
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
8
56
1.44
0.43
2.6
1.7
—
—
—
0
0
(3007164) IgA [Mass/volume] in Serum or Plasma
25
302
0.81
0.42
1.2
1.3
g/l
3.4
2.6
—
9
178
(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
(40759836) Histone Ab [Presence] in Serum by Immunoblot
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
(3018387) Mycoplasma pneumoniae IgG Ab [Units/volume] in Serum
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma
135
1278
1.14
0.41
14.9
7.8
u/l
87.8
79.9
0.97
130
1190
(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay
0
17
0.00
0.41
0.0
1.0
—
—
—
0
0
(3047007) Chlamydophila sp Ab [Presence] in Serum
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
(3004490) Bicarbonate [Moles/volume] standard in Capillary blood
8
61
1.32
0.40
4.8
2.3
mmol/l
24.1
24.5
—
8
56
(40768804) Tissue Pathology biopsy report
59
655
0.87
0.39
2.4
2.2
—
—
—
0
0
(3009445) Proteinase 3 Ab [Units/volume] in Serum
9
67
1.36
0.38
1.2
1.2
—
—
—
0
0
(3005322) IgE [Units/volume] in Serum or Plasma
5
79
0.62
0.36
1.0
1.3
u/ml
397.6
151.0
—
5
74
(3020682) Albumin/Creatinine [Ratio] in Urine
49
546
0.87
0.34
4.2
3.8
mg/mmol
10.4
5.2
0.66
40
348
(3013139) Helicobacter pylori Ag [Presence] in Stool
6
87
0.68
0.33
1.3
1.2
—
—
—
0
0
(3019309) Folate [Moles/volume] in Red Blood Cells
35
307
1.17
0.31
2.2
1.7
nmol/l
1204.0
1125.8
0.13
27
221
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
74
689
1.11
0.28
2.1
2.0
pmol/l
83.6
94.7
1.27
45
362
(3022914) Cancer Ag 19-9 [Units/volume] in Serum or Plasma
5
73
0.68
0.26
4.4
3.6
u/ml
185.3
423.4
—
5
63
(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma
33
370
0.87
0.26
1.9
1.7
pmol/l
455.3
18874598.2
0.50
23
302
(3022313) Gas panel - Capillary blood
9
72
1.26
0.26
4.3
2.2
—
—
—
0
0
(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells
5
38
1.32
0.23
1.6
1.7
—
—
—
0
0
(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma
104
1088
0.92
0.23
4.7
3.1
u/l
105.4
55.4
2.85
97
1015
(3021440) Promyelocytes/100 leukocytes in Blood
15
125
1.21
0.23
6.3
4.8
%
0.0
0.1
—
8
35
(3047181) Lactate [Moles/volume] in Blood
5
40
1.26
0.22
1.8
3.9
mmol/l
1.1
1.2
—
5
34
(40766189) Gliadin peptide IgG Ab [Units/volume] in Serum by Immunoassay
5
41
1.22
0.22
1.0
1.0
—
0.7
—
0
5
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
8
104
0.76
0.21
3.4
1.9
—
—
—
0
0
(1617658) Protocol used for examination of sentinel lymph nodes
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
(4062490)
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(40766048) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum by Immunoassay
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(3023511) Choriogonadotropin [Units/volume] in Urine
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
(3043109) Cytology report of Tissue fine needle aspirate Cyto stain
5
43
1.17
0.21
1.2
1.1
—
—
—
0
0
(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
9
111
0.80
0.20
3.2
2.2
—
—
—
0
0
(3050129) First trimester maternal screen panel - Serum or Plasma
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
(3009340) Metanephrine [Moles/volume] in Serum or Plasma
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
(40766800) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells [Units/volume] corrected for background in Blood
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
(3044889) 12 lead EKG panel
113
1172
0.93
0.19
6.4
3.1
—
—
—
0
0
(3014765) Yersinia sp identified in Stool by Organism specific culture
6
53
1.14
0.19
1.5
1.2
—
—
—
0
0
(42529406) Shigella sp [Presence] in Stool by Culture
6
53
1.14
0.19
1.5
1.2
—
—
—
0
0
(3006418) Campylobacter sp identified in Tissue by Organism specific culture
6
53
1.14
0.19
1.5
1.2
—
—
—
0
0
(3025159) Blasts/100 leukocytes in Blood
14
119
1.19
0.18
5.5
4.8
%
0.0
0.0
—
7
29
(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood
14
121
1.17
0.15
4.4
4.0
mmol/l
1.2
1.2
1.97
14
111
(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma
22
243
0.90
0.14
1.0
1.2
iu/ml
17.6
40.6
—
6
77
(3000492) Spirometry study
15
170
0.87
0.14
1.7
1.5
—
—
—
0
0
(3022145) Colonoscopy Study observation
16
180
0.88
0.14
1.3
1.3
—
—
—
0
0
(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum
9
108
0.83
0.13
2.2
2.5
—
13.8
—
0
6
(3017181) Myelocytes/100 leukocytes in Blood
15
133
1.14
0.12
6.3
4.6
%
0.4
0.8
—
8
38
(3025941) Bacteria identified in Stool by Culture
10
86
1.17
0.11
1.4
1.3
—
—
—
0
0
(3009508) Creatinine [Moles/volume] in Urine
52
542
0.95
0.09
3.5
2.9
mmol/l
8.0
8.3
0.21
47
443
(3015171) Extractable nuclear Ab [Units/volume] in Serum
5
48
1.04
0.09
1.4
1.2
—
0.2
—
0
5
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
10
113
0.88
0.08
1.7
1.4
—
—
—
0
0
(4034850)
5
64
0.78
0.08
10.0
8.1
—
—
—
0
0
(3002179) Metamyelocytes/100 leukocytes in Blood
13
120
1.09
0.05
6.4
4.7
%
0.3
0.4
—
7
28
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
11
119
0.92
0.04
1.5
1.4
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
23
220
1.05
0.03
1.5
1.2
—
—
—
0
0
(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma
65
638
1.03
0.03
2.7
2.2
nmol/l
71.9
76.6
0.57
59
560
(3011397) Hemoglobin [Presence] in Urine by Test strip
37
360
1.03
0.03
4.3
3.2
—
—
—
0
0
(3012516) Albumin [Mass/volume] in Urine
50
510
0.97
0.02
3.8
3.1
mg/l
82.0
158.4
0.26
42
327
(3031040) Bacteria [#/volume] in Urine by Automated count
104
1050
0.98
0.02
5.2
4.0
—
42.8
—
0
20
(36660697) Celiac disease serology panel - Serum
11
117
0.94
0.02
1.1
1.2
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
13
128
1.02
0.00
4.8
2.9
—
—
—
0
0
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
24
237
1.01
0.00
1.0
1.2
u/ml
1.1
13.2
—
7
90
(3004716) Salmonella sp identified in Stool by Organism specific culture
7
73
0.96
0.00
1.4
1.4
—
—
—
0
0
(4211845)
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
(3022575) Varicella zoster virus IgG Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
1549.8
—
0
5
(42529582) MDA5 Ab [Presence] in Serum by Line blot
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3036432) Mycobacterium tuberculosis genotype [Identifier] in Isolate
0
5
0.00
0.00
0.0
6.0
—
—
—
0
0
(3005033) Fetal Nuchal fold Thickness US
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3047352) Trisomy 18 risk [Likelihood] in Fetus
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3053028) Streptococcus sp identified in Specimen by Organism specific culture
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(3022689) Creatine [Moles/volume] in Urine
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3013637) Mi-2 Ab [Presence] in Serum
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3015183) Erythrocyte sedimentation rate
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3035933) Granulocytes/100 leukocytes in Blood
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3008832) Norclozapine [Moles/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
10.3
—
879.3
—
0
9
(3029715) Chromosome analysis.interphase [Interpretation] in Bone marrow by FISH Narrative
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
(3012215) Mononuclear cells/100 leukocytes in Synovial fluid
0
6
0.00
0.00
0.0
1.0
—
30.7
—
0
6
(3019832) Treponema pallidum Ab [Presence] in Serum
8
84
0.95
0.00
2.6
1.7
—
—
—
0
0
(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
8
80
1.00
0.00
1.6
2.0
—
—
—
0
0
(3007847) Interleukin 2 Receptor Soluble [Units/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.8
—
1346.8
—
0
6
(3036669) Protein S actual/normal in Platelet poor plasma by Coagulation assay
0
5
0.00
0.00
0.0
1.4
—
109.2
—
0
5
(3037556) Urate [Mass/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3014271) Vancomycin [Susceptibility]
0
9
0.00
0.00
0.0
2.2
—
—
—
0
0
(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
(3020951) Lymphocytes/100 leukocytes in Cerebral spinal fluid
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3016244) Insulin [Units/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
3.5
—
18.1
—
0
6
(3036535) Thyroglobulin [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
6.8
—
—
—
0
0
(3029075) Extractable nuclear Ab panel - Serum
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3006695) Toxoplasma gondii DNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(42529598) SUMO-activating enzyme subunit 1 Ab [Presence] in Serum by Line blot
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3017704) Immunofixation for Urine
0
7
0.00
0.00
0.0
1.9
—
—
—
0
0
(3009306) Alpha-1-Fetoprotein [Mass/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
3.1
—
—
—
0
0
(3030429) Borrelia sp DNA [Identifier] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3013566) Clostridioides difficile [Presence] in Stool by Organism specific culture
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]
0
9
0.00
0.00
0.0
1.7
—
—
—
0
0
(3006462) Nitrate [Presence] in Urine
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3022192) Triglyceride [Mass/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3011363) Streptococcus pneumoniae Ag [Presence] in Urine
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(3050898) Methicillin resistant Staphylococcus aureus [Presence] in Genital specimen by Organism specific culture
0
9
0.00
0.00
0.0
2.7
—
—
—
0
0
(3043238) Trisomy 21 risk [Likelihood] in Fetus
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
(42868414) European tick borne encephalitis virus IgM Ab [Presence] in Serum by Immunoassay
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3033306) Mononuclear cells/100 leukocytes in Cerebral spinal fluid
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3049714) Procollagen type I.N-terminal propeptide [Mass/volume] in Serum
0
7
0.00
0.00
0.0
1.6
—
55.3
—
0
7
(3017895) Helicobacter pylori Ab [Units/volume] in Serum
5
55
0.91
0.00
1.4
1.6
—
—
—
0
0
(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(43055089) Myosin Ab [Presence] in Serum or Plasma by Immunoblot
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3007821) Glucose [Moles/volume] in Serum or Plasma --baseline
0
7
0.00
0.00
0.0
1.0
—
9.2
—
0
7
(42528593) TIF1-gamma Ab [Presence] in Serum by Line blot
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3026048) Bordetella pertussis IgG Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(4133840)
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint I9_CARDMSEC and mortality.

Females

Parameter HR [95% CI] p-value
I9_CARDMSEC 6.432 [4.18, 9.9] < 0.001
Birth year 0.995 [0.99, 1.0] 0.206

During the follow-up period (1.1.1998 — 31.12.2019), 110 out of 233 females with I9_CARDMSEC died.

Males

Parameter HR [95% CI] p-value
I9_CARDMSEC 7.233 [5.83, 8.98] < 0.001
Birth year 0.986 [0.98, 1.0] 0.003

During the follow-up period (1.1.1998 — 31.12.2019), 480 out of 782 males with I9_CARDMSEC died.

Mortality risk

Mortality risk for people of age

years, who have I9_CARDMSEC.

N-year risk Females Males
1 0.612% 1.675%
5 3.985% 8.275%
10 9.404% 18.906%
15 17.163% 33.051%
20 27.778% 49.542%

Relationships between endpoints

Index endpoint: I9_CARDMSEC – Cardiomyopathies, Secondary/extrinsic

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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