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This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Ototoxic hearing loss, drug-induced

H8_HL_OTOTOX_ADVERSE

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ATC codes for adverse effects of Drugs ANY
  • Hospital discharge: ICD-10 H91.0#

1 out of 7 registries used, show all original rules.

5

4. Check minimum number of events

None

5

5. Include endpoints

None

5

6. Filter based on genotype QC (FinnGen only)

5

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF5
Parent code in ICD-10
H91
Name in latin
Hypacusis ototoxica

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (not available in FinRegistry).

-FinnGen-

Key figures

All Female Male
Number of individuals 5 - -
Unadjusted period prevalence (%) 0.00 - -
Median age at first event (years) 49.49 - -

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
0
18
0.00
0.80
0.0
4.5
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
0
16
0.00
0.51
0.0
2.1
—
—
—
0
0
(3002385) Erythrocyte distribution width [Ratio]
5
35
+∞
0.51
20.2
23.0
%
14.1
13.8
—
5
35
(3044640) Blood type and Crossmatch panel - Blood
0
11
0.00
0.24
0.0
4.6
—
—
—
0
0
(3018677) aPTT in Platelet poor plasma by Coagulation assay
0
9
0.00
0.24
0.0
1.8
—
26.6
—
0
9
(40761511) CBC panel - Blood by Automated count
5
41
+∞
0.24
20.8
19.6
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
0
9
0.00
0.24
0.0
1.2
—
—
—
0
0
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
5
41
+∞
0.24
22.6
16.3
mg/l
27.8
24.6
—
5
34
(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma
5
43
+∞
0.00
10.6
11.5
u/l
28.0
28.9
—
5
43
(3020564) Creatinine [Moles/volume] in Serum or Plasma
5
43
+∞
0.00
22.2
18.9
umol/l
86.0
83.4
—
5
43
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
0
8
0.00
0.00
0.0
4.1
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3022621) pH of Urine by Test strip
0
8
0.00
0.00
0.0
2.5
—
—
—
0
0
(3019150) Specific gravity of Urine by Refractometry
0
5
0.00
0.00
0.0
2.6
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (not available in FinRegistry).

Relationships between endpoints

Index endpoint: H8_HL_OTOTOX_ADVERSE – Ototoxic hearing loss, drug-induced

GWS hits: -

This endpoint is excluded (not available in FinRegistry).