No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
1 out of 7 registries used, show all original rules. |
56 |
4. Check minimum number of eventsNone |
56 |
5. Include endpointsNone |
56 |
6. Filter based on genotype QC (FinnGen only) |
56 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- C
- First used in FinnGen datafreeze
- DF5
- Parent code in ICD-10
- G70
Similar endpoints
↥List of similar endpoints to
Myasthenia gravis, drug-induced
based on the number of shared cases.
Similar with more cases:
- Myasthenia gravis
- Diseases of the myoneural junction and muscle
- Autoimmune diseases
- Used for control exclusion in common control thyroid runs
- Neurological diseases
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (not available in FinRegistry).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 56 | 41 | 15 |
| Unadjusted period prevalence (%) | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | 42.83 | 38.91 | 53.53 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 52
- Matched controls
- 520
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G70.0
ICD-10 Finland
Myasthenia gravis
+∞
72.7
52
*
108
Kela drug reimbursment
Myasthenia gravis
+∞
69.3
50
*
N07AA02
ATC
pyridostigmine; systemic
+∞
67.1
49
*
N07AA03
ATC
distigmine; systemic
+∞
32.8
28
*
3580A
ICD-9 Finland
Myoneural disorders, Myasthenia gravis
+∞
23.8
21
*
R03CA02
ATC
ephedrine; oral
+∞
20.1
18
*
G70.9
ICD-10 Finland
Myoneural disorder, unspecified
+∞
20.1
18
*
A12BA01
ATC
potassium chloride; oral
38.5
19.8
25
12
5872
FHL
Thymic exploration or thymectomy
+∞
16.5
15
*
L04AX01
ATC
azathioprine; systemic
26.0
15.1
21
13
73300
ICD-8 Finland
Other diseases of muscle, tendon and fascia, Myasthenia gravis
+∞
14.2
13
*
G70
ICD-10 Finland
Myasthenia gravis and other myoneural disorders
+∞
8.6
8
*
GEC23
NOMESCO Finland
Transsternal thymectomy
+∞
8.6
8
*
H53.2
ICD-10 Finland
Diplopia
21.3
6.5
9
5
Mortality – FinRegistry
↥This endpoint is excluded (not available in FinRegistry).
Relationships between endpoints
↥Index endpoint: G6_MYASTHENIA_ADVERSE – Myasthenia gravis, drug-induced
GWS hits: -
This endpoint is excluded (not available in FinRegistry).