No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
1 out of 7 registries used, show all original rules. |
402 |
4. Check minimum number of eventsNone |
402 |
5. Include endpointsNone |
402 |
6. Filter based on genotype QC (FinnGen only) |
402 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- C
- First used in FinnGen datafreeze
- DF5
- Parent code in ICD-10
- G43
- Name in latin
- Hemicrania cum aura
Similar endpoints
↥List of similar endpoints to
Migraine with aura, drug-induced
based on the number of shared cases.
Similar with more cases:
- Migraine with aura
- Migraine
- Episodal and paroxysmal disorders
- Neurological diseases
- Neurological diseases, wide definition
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (not available in FinRegistry).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 402 | 325 | 77 |
| Unadjusted period prevalence (%) | 0.10 | 0.11 | 0.03 |
| Median age at first event (years) | 36.04 | 35.51 | 38.29 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 365
- Matched controls
- 3649
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
+∞
323.0
365
148
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
8.5
65.8
175
357
G43.9
ICD-10 Finland
Migraine, unspecified
8.0
37.5
92
147
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
8.2
33.7
80
120
N02CX04
ATC
NA
17.2
29.5
47
31
N02CC04
ATC
rizatriptan; oral
6.2
26.2
76
149
N02CC03
ATC
zolmitriptan; nasal, oral
6.1
25.9
76
151
N03AG01
ATC
valproic acid; systemic, rectal
6.9
24.4
64
109
N03AX11
ATC
topiramate; oral
8.9
21.2
46
58
G43.3
ICD-10 Finland
Complicated migraine
12.3
21.0
38
34
M01AG02
ATC
tolfenamic acid; oral, rectal
3.5
20.6
113
411
N02CC06
ATC
eletriptan; oral
6.7
18.5
48
80
A03FA01
ATC
metoclopramide; systemic, rectal
3.0
18.2
128
550
C07AA05
ATC
propranolol; systemic
3.0
18.1
127
545
N02CC02
ATC
naratriptan; oral
12.4
17.9
32
28
N02CC05
ATC
almotriptan; oral
6.2
16.7
46
83
N02CC07
ATC
frovatriptan; oral
5.5
15.9
48
97
R51.80
ICD-10 Finland
Headache
3.0
14.3
96
388
G43
ICD-10 Finland
Migraine
5.0
14.3
47
105
N02CA52
ATC
ergotamine, combinations excl. psycholeptics; oral
11.6
13.7
25
23
M01AE02
ATC
naproxen; oral, rectal
2.4
13.6
243
1670
N05AB04
ATC
prochlorperazine; systemic, rectal
9.9
13.2
26
28
C08DA01
ATC
verapamil; systemic
6.0
13.1
36
65
N06CA01
ATC
amitriptyline and psycholeptics; systemic
3.4
12.6
65
219
N89
ICPC
Migraine
5.4
11.1
33
66
C07AB02
ATC
metoprolol; systemic
2.7
10.6
79
336
N01
ICPC
Headache
3.3
10.4
54
182
R07.4
ICD-10 Finland
Chest pain, unspecified
2.3
10.4
110
568
N06AA09
ATC
amitriptyline; systemic
3.0
9.3
54
197
C07AB07
ATC
bisoprolol; oral
2.0
9.2
160
1016
A02BC05
ATC
esomeprazole; systemic
2.0
9.2
169
1095
G43.8
ICD-10 Finland
Other migraine
7.4
9.2
21
30
G44.0
ICD-10 Finland
Cluster headache syndrome
11.9
9.2
16
14
N03AX12
ATC
gabapentin; oral
2.5
9.1
77
352
G44.2
ICD-10 Finland
Tension-type headache
2.5
8.7
75
346
C09CA06
ATC
candesartan; oral
2.3
8.7
92
470
M01AE03
ATC
ketoprofen; systemic, rectal
2.0
8.7
148
928
H53.1
ICD-10 Finland
Subjective visual disturbances
3.6
8.2
37
112
M03BX02
ATC
tizanidine; oral
2.0
8.2
257
1999
3460A
ICD-9 Finland
Migraine, Classical migraine
34.2
8.1
10
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.9
7.8
151
979
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.9
7.5
44
162
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
3.8
7.5
30
83
G43.2
ICD-10 Finland
Status migrainosus
13.7
7.4
12
9
A02BA02
ATC
ranitidine; systemic
2.2
7.3
77
390
C08CA06
ATC
nimodipine; systemic
30.7
7.2
9
*
M25.5
ICD-10 Finland
Pain in joint
1.9
7.2
127
793
A02BC01
ATC
omeprazole; systemic
2.0
7.1
107
631
H02AB06
ATC
prednisolone; systemic
1.8
7.0
176
1242
P01AB01
ATC
metronidazole; oral, rectal
1.8
6.8
169
1178
UJF32
NOMESCO Finland
Coloscopy
2.0
6.7
98
567
N06AX21
ATC
duloxetine; oral
2.3
6.6
61
287
R03AC03
ATC
terbutaline; inhalant
2.2
6.5
65
322
AA1AD
NOMESCO Finland
CT of head and brain
2.1
6.4
73
383
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.8
6.4
192
1415
3007
Kela drug reimbursment
Erenumab and fremanezumab
6.5
6.2
15
24
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.1
6.2
75
402
SHA02
NOMESCO Finland
Correction of physiology of bite - basic therapy visit
2.7
6.1
42
169
Mortality – FinRegistry
↥This endpoint is excluded (not available in FinRegistry).
Relationships between endpoints
↥Index endpoint: G6_MIGRAINE_WITH_AURA_ADVERSE – Migraine with aura, drug-induced
GWS hits: -
This endpoint is excluded (not available in FinRegistry).