No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
1 out of 7 registries used, show all original rules. |
435 |
4. Check minimum number of eventsNone |
435 |
5. Include endpointsNone |
435 |
6. Filter based on genotype QC (FinnGen only) |
435 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- C
- First used in FinnGen datafreeze
- DF5
- Parent code in ICD-10
- G43
- Name in latin
- Hemicrania sine aura
Similar endpoints
↥List of similar endpoints to
Migraine without aura, drug-induced
based on the number of shared cases.
Similar with more cases:
- Migraine without aura
- Migraine
- Episodal and paroxysmal disorders
- Neurological diseases
- Neurological diseases, wide definition
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (not available in FinRegistry).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 435 | 348 | 87 |
| Unadjusted period prevalence (%) | 0.10 | 0.12 | 0.04 |
| Median age at first event (years) | 31.29 | 32.91 | 24.80 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 399
- Matched controls
- 3989
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
+∞
323.0
399
129
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
10.9
94.0
223
416
N02CC03
ATC
zolmitriptan; nasal, oral
10.2
53.7
115
152
N02CC04
ATC
rizatriptan; oral
9.1
50.2
115
169
G43.9
ICD-10 Finland
Migraine, unspecified
9.4
48.4
108
151
N02CX04
ATC
NA
24.8
39.6
56
26
C07AA05
ATC
propranolol; systemic
4.1
32.7
165
590
N02CC06
ATC
eletriptan; oral
8.5
27.4
62
84
A03FA01
ATC
metoclopramide; systemic, rectal
3.7
25.6
137
494
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
5.5
25.6
81
175
M01AG02
ATC
tolfenamic acid; oral, rectal
3.8
25.5
132
464
M01AE02
ATC
naproxen; oral, rectal
3.2
24.5
293
1856
N02CC02
ATC
naratriptan; oral
12.5
24.3
44
39
N02CC05
ATC
almotriptan; oral
7.1
23.6
60
97
N06AA09
ATC
amitriptyline; systemic
5.1
22.1
75
174
N06CA01
ATC
amitriptyline and psycholeptics; systemic
4.8
22.1
80
199
N02CA52
ATC
ergotamine, combinations excl. psycholeptics; oral
24.8
21.6
30
13
N03AX11
ATC
topiramate; oral
9.6
21.2
44
51
N05AB04
ATC
prochlorperazine; systemic, rectal
13.2
19.0
33
27
M01AE03
ATC
ketoprofen; systemic, rectal
2.7
18.6
175
890
G43
ICD-10 Finland
Migraine
5.4
17.8
56
118
R51.80
ICD-10 Finland
Headache
3.2
17.1
105
403
N03AG01
ATC
valproic acid; systemic, rectal
4.9
17.0
58
134
G43.3
ICD-10 Finland
Complicated migraine
10.4
16.5
32
33
N02CC07
ATC
frovatriptan; oral
4.9
16.2
55
126
C07AB02
ATC
metoprolol; systemic
3.3
15.4
88
318
R51
ICD-10 Finland
Headache
4.6
15.2
54
130
G44.2
ICD-10 Finland
Tension-type headache
3.1
14.7
92
352
G43.8
ICD-10 Finland
Other migraine
13.2
14.6
25
20
C07AB07
ATC
bisoprolol; oral
2.4
14.3
159
856
C09CA06
ATC
candesartan; oral
2.7
13.3
105
464
N05BA01
ATC
diazepam; systemic, rectal
3.2
13.1
76
274
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.3
13.0
179
1056
M03BX02
ATC
tizanidine; oral
2.2
12.4
280
2047
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.1
11.2
204
1336
3007
Kela drug reimbursment
Erenumab and fremanezumab
9.6
11.1
22
24
N89
ICPC
Migraine
5.0
11.0
35
75
N02CD01
ATC
erenumab; parenteral
11.7
10.7
19
17
M03BC01
ATC
orphenadrine (citrate); systemic
2.2
10.2
122
662
C08DA01
ATC
verapamil; systemic
5.6
9.9
28
53
A02BC01
ATC
omeprazole; systemic
2.2
9.2
110
592
N02AX02
ATC
tramadol; systemic, rectal
2.0
9.1
157
980
N03AX12
ATC
gabapentin; oral
2.5
8.9
75
338
N02BE01
ATC
paracetamol; systemic, rectal
2.2
8.2
342
2913
R518
ICD-10 Finland
NA
17.6
8.1
12
7
G43.2
ICD-10 Finland
Status migrainosus
34.1
8.1
10
*
A02BC02
ATC
pantoprazole; systemic
1.8
7.9
248
1881
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.1
7.9
107
601
N06AX11
ATC
mirtazapine; oral
1.9
7.8
135
835
A02BA02
ATC
ranitidine; systemic
2.2
7.0
79
407
UJF32
NOMESCO Finland
Coloscopy
2.0
7.0
94
523
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.9
7.0
114
685
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.0
6.9
39
139
A02BC03
ATC
lansoprazole; oral
1.9
6.8
115
700
H02AB06
ATC
prednisolone; systemic
1.8
6.8
179
1261
N06AB04
ATC
citalopram; systemic
2.0
6.7
100
581
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.9
6.5
110
666
A02BC05
ATC
esomeprazole; systemic
1.7
6.3
162
1122
N02CD03
ATC
fremanezumab; systemic
9.5
6.3
12
13
G44.8
ICD-10 Finland
Other specified headache syndromes
9.5
6.3
12
13
J01FA10
ATC
azithromycin; systemic
1.7
6.3
260
2076
N03AX16
ATC
pregabalin; oral
1.9
6.1
93
543
R42
ICD-10 Finland
Dizziness and giddiness
2.1
6.1
75
404
J01AA02
ATC
doxycycline; systemic
1.8
6.1
298
2488
A03DA02
ATC
pitofenone and analgesics; systemic
6.9
6.1
14
21
Mortality – FinRegistry
↥This endpoint is excluded (not available in FinRegistry).
Relationships between endpoints
↥Index endpoint: G6_MIGRAINE_NO_AURA_ADVERSE – Migraine without aura, drug-induced
GWS hits: 1
This endpoint is excluded (not available in FinRegistry).