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Lesion of medial popliteal nerve

DOID Endpoint Browser PheWeb

G6_FEMMEPOP

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — G57.4
  • Hospital discharge: ICD-9 — 3554
  • Cause of death: ICD-10 — G57.4
  • Cause of death: ICD-9 — 3554

2 out of 7 registries used, show all original rules.

139

4. Check minimum number of events

None

139

5. Include endpoints

None

139

6. Filter based on genotype QC (FinnGen only)

139

Control definitions (FinnGen only)

Control exclude
G6_NERPLEX

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
G57
Name in latin
Morbositas nervi tibialis

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 945 503 441
Only index persons 875 470 405
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.01
Only index persons 0.02 0.02 0.02
Median age at first event (years)
Whole population 50.49 52.31 48.40
Only index persons 49.98 51.67 48.03

-FinnGen-

Key figures

All Female Male
Number of individuals 139 91 48
Unadjusted period prevalence (%) 0.03 0.03 0.02
Median age at first event (years) 54.13 54.17 54.05

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
121
Matched controls
1208
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G57.4
ICD-10 Finland
Lesion of medial popliteal nerve
+∞
148.3
110
*
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
+∞
26.0
24
*
G57.3
ICD-10 Finland
Lesion of lateral popliteal nerve
148.2
23.5
24
*
G56.0
ICD-10 Finland
Carpal tunnel syndrome
22.6
16.8
24
13
N03AX16
ATC
pregabalin; oral
5.8
15.6
53
143
M79.6
ICD-10 Finland
Pain in limb
4.2
12.5
69
290
N02AX02
ATC
tramadol; systemic, rectal
3.7
10.6
69
321
3554A
ICD-9 Finland
Mononeuritis of lower limb, Lesion of medial popliteal nerve
+∞
10.6
10
*
N03AX12
ATC
gabapentin; oral
4.8
10.0
36
98
ZXD10
NOMESCO Finland
Scheduled procedure
3.4
9.4
65
306
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
3.3
9.2
76
407
ZXA05
NOMESCO Finland
Left side
3.7
9.1
47
176
ACC51
NOMESCO Finland
Release of median nerve
36.0
8.2
10
*
G57.5
ICD-10 Finland
Tarsal tunnel syndrome
85.1
7.5
8
*
G57.8
ICD-10 Finland
Other mononeuropathies of lower limb
85.1
7.5
8
*
M25.5
ICD-10 Finland
Pain in joint
3.1
7.4
50
223
J01MA14
ATC
moxifloxacin; systemic
4.9
7.3
24
58
XA402
NOMESCO Finland
ENMG
21.6
7.3
10
5
G57.6
ICD-10 Finland
Lesion of plantar nerve
32.1
7.3
9
*
M19.0
ICD-10 Finland
Primary arthrosis of other joints
5.4
7.1
21
45
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
3.8
7.1
32
105
M77.4
ICD-10 Finland
Metatarsalgia
6.2
6.9
18
33
Z3231
NOMESCO Finland
Registered nurse
3.0
6.7
45
197
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
3.8
6.5
28
88
ZXA00
NOMESCO Finland
Right side
3.0
6.4
44
196
ACB19
NOMESCO Finland
Excision of lesion of peripheral nerve other or unspecified
+∞
6.3
6
*

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
81
531
2.26
5.20
5.2
6.0
mmol/l
1.2
1.2
0.12
75
447
(42870588) Differential panel, method unspecified - Blood
60
349
2.27
5.14
3.6
6.0
—
—
—
0
0
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
39
197
2.36
4.57
3.9
3.5
ng/l
35.4
325.0
1.03
27
149
(3018418) pH of Serum or Plasma
57
339
2.16
4.50
2.8
3.7
ph
7.4
7.4
—
8
69
(3006315) Basophils [#/volume] in Blood
80
545
2.10
4.39
4.6
6.0
e9/l
0.0
0.0
0.39
66
482
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
13
36
3.88
4.32
1.4
1.4
—
—
—
0
0
(3013115) Eosinophils [#/volume] in Blood
81
562
2.06
4.15
4.7
6.3
e9/l
0.2
0.2
0.38
70
499
(3001604) Monocytes [#/volume] in Blood
79
544
2.05
4.12
4.5
6.0
e9/l
0.6
0.6
0.26
65
481
(3019198) Lymphocytes [#/volume] in Blood
80
554
2.05
4.10
4.5
6.0
e9/l
1.9
2.0
0.21
68
498
(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum
8
11
7.64
3.91
1.4
1.1
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
26
117
2.50
3.87
1.8
1.4
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
31
154
2.30
3.72
1.3
1.3
—
—
—
0
0
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
65
433
1.94
3.58
2.2
1.8
pmol/l
92.9
98.1
0.34
33
191
(3042936) Bacteria identified in Isolate by Culture
31
157
2.25
3.55
2.5
1.8
—
—
—
0
0
(3013650) Neutrophils [#/volume] in Blood by Automated count
88
652
1.95
3.50
5.3
9.4
e9/l
4.3
3.9
0.64
72
564
(3023368) Bacteria identified in Blood by Culture
45
269
1.99
3.35
4.0
4.0
—
—
—
0
0
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
131
1162
3.21
3.32
19.1
12.1
mg/l
23.0
22.8
0.03
116
871
(3021589) Normoblasts [#/volume] in Blood
71
500
1.86
3.20
6.6
9.1
e9/l
0.0
0.0
0.47
53
409
(3004588) Protein electrophoresis panel - Serum or Plasma
17
70
2.63
3.01
1.4
2.0
—
—
—
0
0
(40758558) Short blood count panel - Blood
45
278
1.91
3.01
3.5
6.7
—
—
—
0
0
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
42
254
1.94
2.99
2.0
1.7
mg/l
0.6
1.1
1.86
28
206
(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma
41
246
1.95
2.99
2.6
1.9
mg/l
2.9
3.2
0.39
35
211
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
24
119
2.23
2.87
2.2
1.8
—
—
—
0
0
(3029338) Protein.monoclonal band 3 [Mass/volume] in Serum or Plasma by Electrophoresis
9
24
3.93
2.72
1.6
1.2
g/l
0.0
0.0
—
9
24
(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis
9
24
3.93
2.72
1.6
1.2
g/l
0.0
0.0
—
9
24
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
68
491
1.75
2.69
4.9
3.8
—
—
—
0
0
(3021879) Hepatitis B virus core Ab [Presence] in Serum
16
68
2.53
2.67
1.3
1.6
—
—
—
0
0
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
125
1094
2.42
2.61
5.0
4.5
mu/l
2.0
1.9
0.13
120
986
(3035797) Protein.monoclonal band 2 [Mass/volume] in Serum or Plasma by Electrophoresis
9
26
3.63
2.53
1.6
1.3
g/l
0.0
0.0
—
9
26
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
127
1124
2.50
2.49
15.7
11.4
ml/min/173m2
82.3
81.5
0.17
107
900
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
40
252
1.82
2.47
1.3
1.2
u/ml
1.0
1.5
0.35
14
80
(36660697) Celiac disease serology panel - Serum
17
78
2.34
2.43
1.5
1.2
—
—
—
0
0
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
8
22
3.79
2.40
1.5
1.1
—
—
—
0
0
(3022621) pH of Urine by Test strip
16
72
2.38
2.38
2.4
2.3
—
—
—
0
0
(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum
11
41
2.83
2.34
1.1
1.1
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
25
138
1.99
2.28
1.4
1.4
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
22
116
2.07
2.26
2.5
1.8
—
—
—
0
0
(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum
17
81
2.25
2.23
2.6
2.4
—
6.8
—
0
5
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
29
170
1.89
2.23
2.4
1.9
—
—
—
0
0
(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay
6
14
4.43
2.17
2.2
1.0
—
—
—
0
0
(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay
6
14
4.43
2.17
2.2
1.0
—
—
—
0
0
(3018095) Leukocytes [#/volume] in Urine
56
402
1.66
2.15
4.4
3.3
e6/l
150.5
107.2
0.12
40
279
(3044889) 12 lead EKG panel
99
823
1.71
2.12
3.4
3.6
—
—
—
0
0
(3017143) Hepatitis C virus Ab [Presence] in Serum
21
112
2.03
2.10
1.6
1.7
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
48
333
1.67
2.09
3.2
2.1
—
—
—
0
0
(3002582) Erythrocytes [#/volume] in Urine
48
333
1.67
2.09
3.4
2.8
e6/l
14.4
52.2
1.16
37
247
(3044927) Protein electrophoresis panel - Urine
5
10
5.14
2.09
1.0
1.1
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
54
389
1.63
2.02
3.3
2.8
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
47
329
1.65
1.96
3.6
2.7
—
—
—
0
0
(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain
5
11
4.67
1.96
1.2
1.2
—
—
—
0
0
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
8
28
2.97
1.89
1.5
1.5
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
38
254
1.68
1.88
4.0
2.0
—
—
—
0
0
(3007164) IgA [Mass/volume] in Serum or Plasma
35
230
1.70
1.84
1.3
1.4
g/l
2.9
2.2
1.08
19
143
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
15
74
2.15
1.83
1.4
1.6
—
—
—
0
0
(3052851) Hemolysis interference index of Serum or Plasma
8
29
2.86
1.82
3.6
3.5
—
—
—
0
0
(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing
7
24
3.01
1.74
2.1
1.3
—
—
—
0
0
(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma
7
24
3.01
1.74
1.9
2.6
—
—
—
0
0
(3023410) Appearance of Cerebral spinal fluid
5
13
3.95
1.73
1.2
1.1
—
—
—
0
0
(3009508) Creatinine [Moles/volume] in Urine
46
331
1.58
1.69
3.3
3.0
mmol/l
7.7
7.6
0.06
39
274
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
127
1163
2.07
1.62
4.8
4.4
mmol/l
6.2
5.9
1.22
122
1058
(3012516) Albumin [Mass/volume] in Urine
44
317
1.57
1.60
3.8
3.1
mg/l
1165.4
467.5
0.26
33
202
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
25
156
1.73
1.57
3.3
2.6
e6/l
2.5
2.9
—
9
78
(3011397) Hemoglobin [Presence] in Urine by Test strip
36
248
1.61
1.57
3.6
3.1
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
92
780
1.53
1.55
4.6
3.9
—
—
—
0
0
(3023511) Choriogonadotropin [Units/volume] in Urine
5
15
3.42
1.53
1.2
1.4
—
—
—
0
0
(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma
6
21
2.94
1.52
3.8
1.6
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
87
731
1.51
1.52
2.9
2.9
—
—
—
0
0
(3019309) Folate [Moles/volume] in Red Blood Cells
28
184
1.65
1.47
1.5
1.7
nmol/l
936.4
1242.2
1.55
22
134
(3030467) Casts [#/volume] in Urine by Automated count
42
305
1.54
1.46
3.4
2.6
e6/l
0.3
0.4
0.46
31
218
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
27
176
1.66
1.46
3.2
2.3
e6/l
0.7
0.8
0.17
11
97
(3021901) Oxygen saturation in Capillary blood
5
16
3.20
1.45
2.2
2.7
—
—
—
0
0
(3028271) Lactate [Moles/volume] in Capillary blood
5
16
3.20
1.45
1.4
2.3
mmol/l
2.8
1.4
—
5
16
(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma
60
471
1.48
1.44
2.4
2.2
nmol/l
89.8
78.8
1.55
55
419
(3020682) Albumin/Creatinine [Ratio] in Urine
46
342
1.52
1.44
4.0
3.9
mg/mmol
4.0
6.1
0.41
33
211
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
129
1199
2.05
1.39
5.3
4.9
mmol/l
2.8
2.8
0.14
122
1100
(3033658) Prothrombin time (PT) actual/Normal
38
273
1.54
1.38
4.4
3.2
%
91.1
94.1
0.35
38
266
(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay
6
23
2.68
1.38
1.2
1.3
—
—
—
0
0
(3044290) Cell count panel - Cerebral spinal fluid
6
23
2.68
1.38
1.0
1.0
—
—
—
0
0
(3024928) Oxygen saturation in Venous blood
5
17
3.01
1.37
1.2
3.4
—
—
—
0
0
(3042111) Morphology [Interpretation] in Bone marrow Narrative
5
17
3.01
1.37
1.2
2.6
—
—
—
0
0
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
127
1176
1.93
1.36
4.5
4.4
mmol/l
4.8
4.7
0.22
121
1086
(3007628) Bicarbonate [Moles/volume] standard in Venous blood
9
43
2.17
1.33
1.8
4.0
mmol/l
24.7
24.6
—
9
37
(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection
9
43
2.17
1.33
2.1
1.6
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
21
131
1.71
1.33
1.9
1.5
—
—
—
0
0
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
28
189
1.60
1.32
1.3
1.3
u/ml
1.3
11.4
1.80
14
76
(3014051) Protein [Presence] in Urine by Test strip
5
18
2.84
1.29
1.6
1.9
—
—
—
0
0
(3022250) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Lactate to pyruvate reaction
18
109
1.75
1.26
2.4
5.5
u/l
226.2
242.2
0.20
18
102
(3024891) Influenza virus A+B Ag [Presence] in Specimen
6
25
2.46
1.25
1.7
1.1
—
—
—
0
0
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
123
1134
1.74
1.25
3.9
3.9
mmol/l
1.5
1.3
2.63
117
1041
(3021447) Carbon dioxide [Partial pressure] in Venous blood
16
94
1.79
1.23
2.1
4.0
kpa
5.6
5.9
0.53
16
94
(3045414) Leukocytes [Presence] in Urine
8
37
2.23
1.23
1.5
1.6
—
—
—
0
0
(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection
5
19
2.69
1.22
1.4
1.9
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
28
193
1.56
1.22
1.3
1.4
—
—
—
0
0
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
8
38
2.17
1.20
1.6
1.9
—
—
—
0
0
(3008037) Lactate [Moles/volume] in Venous blood
6
26
2.36
1.20
1.7
3.3
mmol/l
1.1
1.3
—
6
26
(4035726)
5
113
0.42
1.19
1.4
1.4
—
—
—
0
0
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
12
65
1.93
1.17
1.9
1.7
—
—
—
0
0
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
8
40
2.06
1.14
1.8
2.2
—
—
—
0
0
(3013290) Carbon dioxide [Partial pressure] in Blood
5
21
2.43
1.10
3.6
3.2
kpa
5.0
5.2
—
5
21
(1001926) Buprenorphine [Presence] in Urine by Screen method
5
21
2.43
1.10
1.6
1.3
—
—
—
0
0
(3027315) Oxygen [Partial pressure] in Blood
5
21
2.43
1.10
3.6
3.2
kpa
8.9
7.9
—
5
21
(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection
7
33
2.18
1.07
1.6
1.5
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
40
306
1.43
1.06
3.4
2.5
—
—
—
0
0
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
51
408
1.39
1.05
3.6
3.6
ng/l
1232.0
33.1
0.50
38
278
(3012336) Haptoglobin [Mass/volume] in Serum or Plasma
9
47
1.98
1.04
1.3
2.4
g/l
1.5
1.5
—
9
42
(3023939) Sjogrens syndrome-A extractable nuclear Ab [Units/volume] in Serum
5
22
2.32
1.04
1.4
1.4
—
20.2
—
0
5
(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection
5
22
2.32
1.04
1.4
1.9
—
—
—
0
0
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
10
53
1.96
1.04
15.2
8.0
—
—
—
0
0
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
125
1170
1.68
1.03
4.4
4.4
mmol/l
1.5
1.5
0.20
118
1075
(3000330) Specific gravity of Urine by Test strip
9
49
1.89
1.01
3.4
3.4
—
—
—
0
0
(3032080) INR in Blood by Coagulation assay
52
422
1.37
0.98
5.1
6.8
inr
1.1
1.2
0.54
18
121
(3024354) Oxygen [Partial pressure] in Venous blood
13
78
1.74
0.95
2.1
2.8
kpa
4.5
4.3
0.32
13
78
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
5
102
0.47
0.94
1.2
1.6
—
—
—
0
0
(3016879) Cocaine [Presence] in Urine
6
28
2.19
0.92
1.5
1.3
—
—
—
0
0
(3012544) pH of Venous blood
15
97
1.61
0.85
1.7
4.0
—
—
—
0
0
(3028300) Cannabinoids [Presence] in Urine
6
31
1.98
0.85
1.5
1.3
—
—
—
0
0
(3027008) Opiates [Presence] in Urine
6
31
1.98
0.85
1.5
1.3
—
—
—
0
0
(3017895) Helicobacter pylori Ab [Units/volume] in Serum
6
32
1.91
0.83
1.5
1.6
—
—
—
0
0
(3027944) Amphetamines [Presence] in Urine
6
32
1.91
0.83
1.5
1.3
—
—
—
0
0
(3000764) Benzodiazepines [Presence] in Urine
6
32
1.91
0.83
1.5
1.3
—
—
—
0
0
(3049717) Cytology report of Urine Cyto stain
6
33
1.85
0.80
2.0
2.9
—
—
—
0
0
(3026782) Osmolality of Urine
27
203
1.41
0.78
2.5
2.6
mosm/kgh2o
549.8
548.9
0.01
21
174
(46235355) HIV 1 and 2 tests - Meaningful Use set
23
168
1.44
0.78
2.3
1.7
—
—
—
0
0
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
9
53
1.75
0.77
13.3
6.3
mmol/l
25.8
25.1
—
9
53
(40761511) CBC panel - Blood by Automated count
128
1220
1.62
0.76
12.6
11.6
—
—
—
0
0
(3051387) C reactive protein [Mass/volume] in Capillary blood
5
24
2.12
0.75
2.4
4.8
mg/l
17.0
34.4
—
5
16
(3038515) Glucose [Moles/volume] in Venous blood
5
24
2.12
0.75
1.8
3.5
mmol/l
7.0
8.1
—
5
24
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
9
142
0.61
0.74
7.1
6.5
—
—
—
0
0
(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection
7
39
1.84
0.73
1.0
1.3
—
—
—
0
0
(3022145) Colonoscopy Study observation
18
127
1.48
0.72
1.2
1.3
—
—
—
0
0
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
16
110
1.51
0.72
2.2
3.2
—
—
—
0
0
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
9
58
1.59
0.71
1.2
1.3
—
—
—
0
0
(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma
10
61
1.69
0.70
2.7
2.9
pmol/l
4.6
4.4
—
10
54
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
5
27
1.88
0.69
1.8
1.4
—
—
—
0
0
(3037756) Immunofixation for Serum or Plasma
5
28
1.81
0.67
1.0
1.7
—
—
—
0
0
(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay
5
28
1.81
0.67
1.8
1.4
—
—
—
0
0
(3000991) Gas panel - Venous blood
12
79
1.57
0.65
13.8
6.7
—
—
—
0
0
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
5
29
1.75
0.64
1.4
1.9
—
—
—
0
0
(3022217) INR in Platelet poor plasma by Coagulation assay
19
140
1.41
0.62
26.2
19.5
inr
1.2
1.5
—
7
16
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
5
30
1.69
0.62
1.4
1.8
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
33
268
1.30
0.60
1.3
1.3
—
—
—
0
0
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
6
35
1.75
0.58
3.3
2.4
—
—
—
0
0
(3015736) pH of Urine
51
443
1.24
0.54
3.8
2.9
—
—
—
0
0
(1002224) Polysomnography panel
9
62
1.48
0.54
1.2
1.1
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
6
97
0.60
0.54
6.2
3.2
—
—
—
0
0
(3029937) Albumin [Presence] in Urine by Test strip
25
308
0.77
0.52
5.4
3.4
estimate
0.0
0.0
—
6
104
(3002256) Pathology report gross observation
20
157
1.32
0.46
1.6
1.3
—
—
—
0
0
(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma
12
86
1.43
0.46
4.8
2.6
ug/l
6.0
8.1
0.21
12
77
(3008898) HLA-B27 [Presence]
7
50
1.42
0.46
1.1
1.1
—
—
—
0
0
(3001019) Free T4 and TSH panel - Serum or Plasma
7
51
1.39
0.44
2.4
1.5
—
—
—
0
0
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
5
31
1.64
0.43
1.4
1.3
—
—
—
0
0
(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells
5
32
1.58
0.42
1.0
2.3
—
—
—
0
0
(3028026) IgM [Mass/volume] in Serum or Plasma
11
79
1.43
0.42
1.3
1.6
g/l
0.9
1.6
1.08
11
70
(1617658) Protocol used for examination of sentinel lymph nodes
0
17
0.00
0.41
0.0
1.2
—
—
—
0
0
(3028167) CD3+CD4+ (T4 helper) cells [#/volume] in Blood
0
18
0.00
0.40
0.0
2.1
—
711.0
—
0
8
(40768795) Lymph node Pathology biopsy report
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
(3013139) Helicobacter pylori Ag [Presence] in Stool
9
66
1.39
0.39
1.2
1.2
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
41
461
0.84
0.36
3.0
2.9
—
—
—
0
0
(3004248) Sex hormone binding globulin [Moles/volume] in Serum or Plasma
6
42
1.45
0.36
1.7
1.9
nmol/l
42.3
38.8
—
6
42
(3019832) Treponema pallidum Ab [Presence] in Serum
10
73
1.40
0.35
2.8
1.5
—
—
—
0
0
(3022313) Gas panel - Capillary blood
6
43
1.41
0.35
2.8
3.4
—
—
—
0
0
(21494755) Public health laboratory ask at order entry panel
10
132
0.74
0.34
1.8
1.3
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
54
492
1.16
0.32
2.6
2.1
—
—
—
0
0
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
7
54
1.31
0.31
2.0
2.4
%
1.2
1.1
—
7
54
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
7
54
1.31
0.31
1.0
1.0
—
—
—
0
0
(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood
7
54
1.31
0.31
3.1
3.4
%
41.7
48.2
—
7
54
(3041096) Erythrocytes [Presence] in Urine by Automated
29
330
0.85
0.29
4.8
2.9
—
—
—
0
0
(3009343) pH of Capillary blood
8
62
1.31
0.28
2.4
3.2
—
7.4
—
0
9
(3035350) Ketones [Presence] in Urine by Test strip
61
566
1.14
0.28
4.3
3.2
estimate
0.0
0.0
—
5
106
(3019060) Gas panel - Arterial blood
8
64
1.27
0.28
4.8
4.8
—
—
—
0
0
(3000492) Spirometry study
13
104
1.28
0.27
1.4
1.3
—
—
—
0
0
(3009542) Hematocrit [Volume Fraction] of Blood
113
1094
1.18
0.26
19.7
12.7
%
40.5
40.6
0.04
88
806
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
41
448
0.88
0.24
5.0
3.2
—
—
—
0
0
(3003327) Ova and parasites identified in Stool by Light microscopy
5
37
1.36
0.24
1.0
1.7
—
—
—
0
0
(3014765) Yersinia sp identified in Stool by Organism specific culture
5
42
1.20
0.21
1.2
1.2
—
—
—
0
0
(3006418) Campylobacter sp identified in Tissue by Organism specific culture
5
42
1.20
0.21
1.2
1.2
—
—
—
0
0
(3014702) Chromogranin A [Moles/volume] in Serum or Plasma
0
11
0.00
0.21
0.0
3.1
—
2.9
—
0
11
(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count
0
11
0.00
0.21
0.0
4.2
—
—
—
0
0
(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection
0
11
0.00
0.21
0.0
2.5
—
—
—
0
0
(4281824)
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
(3000081) cloZAPine [Moles/volume] in Serum or Plasma
0
10
0.00
0.21
0.0
21.0
—
1568.8
—
0
10
(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
(3027529) Toxoplasma gondii IgM Ab [Units/volume] in Serum
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
(3008832) Norclozapine [Moles/volume] in Serum or Plasma
0
10
0.00
0.21
0.0
13.2
—
882.2
—
0
10
(3012447) Hantavirus puumala IgG Ab [Titer] in Serum
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(3028369) Herpes simplex virus 1+2 DNA [Presence] in Specimen by NAA with probe detection
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
(3013512) EKG study
30
332
0.88
0.21
4.1
3.7
—
—
—
0
0
(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum
0
12
0.00
0.21
0.0
2.3
—
—
—
0
0
(3029080) Hemoglobin [Entitic mass] in Reticulocytes
0
12
0.00
0.21
0.0
3.1
—
32.6
—
0
12
(3001467) Alkaline phosphatase.bone [Enzymatic activity/volume] in Serum or Plasma
0
12
0.00
0.21
0.0
1.1
—
64.9
—
0
7
(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
(3032773) Endomysium IgG Ab [Titer] in Serum
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection
0
12
0.00
0.21
0.0
2.3
—
—
—
0
0
(40766183) Gliadin peptide IgA Ab [Units/volume] in Serum by Immunoassay
0
12
0.00
0.21
0.0
1.2
—
3.3
—
0
7
(3020717) Zinc [Moles/volume] in Serum or Plasma
0
12
0.00
0.21
0.0
1.2
—
19.3
—
0
12
(40768800) Prostate Pathology biopsy report
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
(3005570) Glucose [Moles/volume] in Urine
0
13
0.00
0.21
0.0
2.2
—
—
—
0
0
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
9
113
0.78
0.21
1.9
1.9
—
—
—
0
0
(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
(3008757) Leukocyte morphology finding [Identifier] in Blood
0
14
0.00
0.20
0.0
4.1
—
—
—
0
0
(40761535) Cells panel - Urine sediment
10
81
1.25
0.19
3.6
3.3
—
—
—
0
0
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
7
62
1.14
0.17
2.4
2.3
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
30
274
1.12
0.17
5.1
5.7
—
—
—
0
0
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
6
80
0.74
0.16
1.7
1.5
—
—
—
0
0
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
26
237
1.12
0.15
3.7
4.0
%
23.8
22.0
—
9
103
(3021601) Nitrite [Presence] in Urine by Test strip
60
572
1.09
0.15
6.7
4.3
estimate
0.0
0.0
—
5
104
(3013742) Prealbumin [Mass/volume] in Serum or Plasma
9
105
0.85
0.13
1.0
2.2
g/l
0.2
0.2
—
9
98
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
11
96
1.16
0.10
1.6
1.3
—
—
—
0
0
(42529406) Shigella sp [Presence] in Stool by Culture
5
43
1.17
0.10
1.2
1.2
—
—
—
0
0
(3027273) Bicarbonate [Moles/volume] in Venous blood
6
56
1.07
0.09
2.7
3.6
mmol/l
24.3
25.2
—
6
56
(3017732) Neutrophils [#/volume] in Blood
6
73
0.81
0.08
1.0
1.7
e9/l
3.5
4.1
—
6
53
(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood
9
100
0.89
0.06
3.8
3.8
mmol/l
1.2
1.2
—
9
90
(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma
17
177
0.95
0.01
1.8
2.7
ug/l
0.6
0.7
—
10
111
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
10
94
1.07
0.01
4.0
1.7
—
—
—
0
0
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
10
104
0.96
0.00
4.3
1.9
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
19
194
0.98
0.00
2.1
1.5
—
—
—
0
0
(3019150) Specific gravity of Urine by Refractometry
25
246
1.02
0.00
4.4
3.4
kg/l
1.0
1.0
—
5
27
(3019225) pH of Specimen
10
102
0.98
0.00
2.1
3.8
—
—
—
0
0
(3037556) Urate [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3005156) Respiratory syncytial virus A RNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
2.7
—
—
—
0
0
(3028433) Virus identified in Specimen by Culture
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(21493690) Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood
0
7
0.00
0.00
0.0
2.9
—
—
—
0
0
(3022058) Hepatitis B virus DNA [Presence] in Serum or Plasma by NAA with probe detection
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3023601) Vancomycin resistant enterococcus [Presence] in Specimen by Organism specific culture
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection
0
8
0.00
0.00
0.0
2.3
—
—
—
0
0
(3020876) Protein [Mass/time] in 24 hour Urine
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
(3000108) Respiratory syncytial virus B RNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
2.7
—
—
—
0
0
(3025941) Bacteria identified in Stool by Culture
7
73
0.96
0.00
1.3
1.2
—
—
—
0
0
(3035933) Granulocytes/100 leukocytes in Blood
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3010838) Calcium [Moles/time] in 24 hour Urine
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
(3008536) Aspergillus sp Ab [Presence] in Serum
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3014271) Vancomycin [Susceptibility]
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
(3000012) Reticulocyte production index
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
(3004446) Plasmodium sp identified in Blood by Light microscopy
0
5
0.00
0.00
0.0
3.0
—
—
—
0
0
(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection
0
8
0.00
0.00
0.0
2.3
—
—
—
0
0
(3019897) Erythrocyte distribution width [Ratio] by Automated count
0
8
0.00
0.00
0.0
2.0
—
12.9
—
0
8
(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3045066) Thymidine kinase [Enzymatic activity/volume] in Serum
0
8
0.00
0.00
0.0
1.6
—
15.2
—
0
8
(3035880) pH of Pleural fluid
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3019420) Tryptase [Mass/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.6
—
8.8
—
0
7
(3022575) Varicella zoster virus IgG Ab [Units/volume] in Serum
0
6
0.00
0.00
0.0
1.0
—
1265.7
—
0
6
(40757349) CD3+CD4+ (T4 helper) cells/CD3+CD8+ (T8 suppressor cells) cells [# Ratio] in Blood
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
(40768441) Liver Pathology biopsy report
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3012565) Volume of 24 hour Urine
0
6
0.00
0.00
0.0
1.8
—
1815.8
—
0
6
(3036428) Adenosine deaminase [Enzymatic activity/volume] in Pleural fluid
0
6
0.00
0.00
0.0
1.5
—
7.7
—
0
6
(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection
0
8
0.00
0.00
0.0
2.3
—
—
—
0
0
(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection
0
8
0.00
0.00
0.0
2.3
—
—
—
0
0
(3004716) Salmonella sp identified in Stool by Organism specific culture
7
73
0.96
0.00
1.3
1.3
—
—
—
0
0
(3007821) Glucose [Moles/volume] in Serum or Plasma --baseline
0
6
0.00
0.00
0.0
1.2
—
9.9
—
0
6
(4010399)
9
89
1.01
0.00
1.9
1.5
—
—
—
0
0
(3026515) Parvovirus B19 IgM Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(40760847) Basement membrane Ab [Titer] in Serum by Immunofluorescence
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(3009550) Parvovirus B19 IgG Ab [Titer] in Serum
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3035947) Staphylolysin Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3052649) Adenosine deaminase [Enzymatic activity/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
2.2
—
10.7
—
0
6
(3036669) Protein S actual/normal in Platelet poor plasma by Coagulation assay
0
5
0.00
0.00
0.0
1.2
—
120.8
—
0
5
(3013727) Leukocytes other/100 leukocytes in Blood
0
7
0.00
0.00
0.0
4.3
—
45.1
—
0
7
(21493195) Respiratory pathogens DNA and RNA tested for in Respiratory system specimen by NAA with probe detection
0
6
0.00
0.00
0.0
2.7
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint G6_FEMMEPOP and mortality.

Females

Parameter HR [95% CI] p-value
G6_FEMMEPOP 1.318 [0.96, 1.81] 0.09
Birth year 0.994 [0.99, 1.0] 0.183

During the follow-up period (1.1.1998 — 31.12.2019), 52 out of 398 females with G6_FEMMEPOP died.

Males

Parameter HR [95% CI] p-value
G6_FEMMEPOP 1.459 [1.03, 2.06] 0.033
Birth year 0.989 [0.98, 1.0] 0.025

During the follow-up period (1.1.1998 — 31.12.2019), 65 out of 344 males with G6_FEMMEPOP died.

Mortality risk

Mortality risk for people of age

years, who have G6_FEMMEPOP.

N-year risk Females Males
1 0.125% 0.326%
5 0.826% 1.77%
10 1.935% 4.382%
15 3.731% 8.464%
20 6.789% 14.152%

Relationships between endpoints

↥

Index endpoint: G6_FEMMEPOP – Lesion of medial popliteal nerve

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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