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Disorders of brain, other and unspecified

DOID EFO Endpoint Browser PheWeb

G6_DISBROTHUNS

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — G93.8, G93.90, G93.99, G94.8*
  • Hospital discharge: ICD-9 — 348[8-9]
  • Hospital discharge: ICD-8 — 3479[8-9]
  • Cause of death: ICD-10 — G93.8, G93.90, G93.99, G94.8*
  • Cause of death: ICD-9 — 348[8-9]
  • Cause of death: ICD-8 — 3479[8-9]

2 out of 7 registries used, show all original rules.

351

4. Check minimum number of events

None

351

5. Include endpoints

None

351

6. Filter based on genotype QC (FinnGen only)

351

Control definitions (FinnGen only)

Control exclude
G6_OTHNEU

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 4808 2024 2697
Only index persons 2930 1376 1554
Unadjusted period prevalence (%)
Whole population 0.07 0.06 0.08
Only index persons 0.06 0.05 0.06
Median age at first event (years)
Whole population 48.81 47.92 49.20
Only index persons 41.61 43.17 40.23

-FinnGen-

Key figures

All Female Male
Number of individuals 351 153 198
Unadjusted period prevalence (%) 0.07 0.05 0.09
Median age at first event (years) 47.34 42.25 51.27

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
323
Matched controls
3228
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G93.99
ICD-10 Finland
Disorder of brain, unspecified
+∞
69.3
64
*
G93.8
ICD-10 Finland
Other specified disorders of brain
+∞
64.8
60
*
34799
ICD-8 Finland
Other disease of brain, Other and unspecified
+∞
63.7
59
*
34798
ICD-8 Finland
Other disease of brain, Alii definiti
+∞
53.6
50
*
G93.90
ICD-10 Finland
Brain death
+∞
42.6
40
*
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
9.1
27.0
59
77
3489X
ICD-9 Finland
Other conditions of brain, Unspecified condition of brain
+∞
21.1
20
*
3488X
ICD-9 Finland
Other conditions of brain
+∞
20.0
19
*
YKA02
NOMESCO Finland
Excision of kidneys from cadaver donor
+∞
20.0
19
*
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
74.4
18.9
21
*
G40.9
ICD-10 Finland
Epilepsy, unspecified
8.9
16.8
36
45
AA1AD
NOMESCO Finland
CT of head and brain
3.3
16.6
97
367
YJA10
NOMESCO Finland
Excision of liver from cadaver donor
+∞
12.6
12
*
G93.4
ICD-10 Finland
Encephalopathy, unspecified
124.2
11.5
12
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.2
11.3
66
243
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
4.6
11.2
39
93
TAB00
NOMESCO Finland
Lumbar puncture
6.9
11.1
27
42
N03AX14
ATC
levetiracetam; systemic
9.4
10.9
22
25
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
22.4
10.8
15
7
G93.9
ICD-10 Finland
Disorder of brain, unspecified
+∞
10.5
10
*
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
9.6
10.2
20
22
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
8.4
9.5
20
25
N05BA01
ATC
diazepam; systemic, rectal
2.9
9.4
58
223
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
3.8
9.2
39
113
R51.80
ICD-10 Finland
Headache
3.2
9.0
48
166
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
8.6
8.7
18
22
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
3.7
8.5
37
110
I46.0
ICD-10 Finland
Cardiac arrest with successful resuscitation
8.9
8.4
17
20
N03AF01
ATC
carbamazepine; oral, rectal
3.9
8.4
34
95
R42
ICD-10 Finland
Dizziness and giddiness
2.4
8.1
77
377
183
Kela drug reimbursment
Lamotrigin and topiramate
22.7
8.1
11
5
R56.8
ICD-10 Finland
Other and unspecified convulsions
4.3
7.9
28
69
XA800
NOMESCO Finland
Neuropsychological investigation
5.0
7.8
24
51
AA5BD
NOMESCO Finland
CT of cerebral ischaemia
12.2
7.6
13
11
N03AF02
ATC
oxcarbazepine; oral
5.8
7.5
20
36
G45.1
ICD-10 Finland
Carotid artery syndrome (hemispheric)
+∞
7.3
7
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.9
7.2
28
76
R41.0
ICD-10 Finland
Disorientation, unspecified
5.7
7.0
19
35
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.3
6.9
33
106
WX892
NOMESCO Finland
Monitored bed care
3.2
6.8
34
113
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.1
6.8
92
522
N06AB04
ATC
citalopram; systemic
2.2
6.6
74
388
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.4
6.6
30
93
N03AX09
ATC
lamotrigine; oral
4.8
6.4
20
44
N05AH03
ATC
olanzapine; systemic
3.6
6.4
27
79
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
6.2
6.4
16
27
N03AG01
ATC
valproic acid; systemic, rectal
3.7
6.4
26
74
G93.1
ICD-10 Finland
Anoxic brain damage, not elsewhere classified
+∞
6.3
6
*
G93.0
ICD-10 Finland
Cerebral cysts
+∞
6.3
6
*
YFA50
NOMESCO Finland
Excision of heart for preparation of homograft
+∞
6.3
6
*
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
2.7
6.2
42
169

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3044290) Cell count panel - Cerebral spinal fluid
27
45
6.42
15.83
1.6
1.3
—
—
—
0
0
(3016914) Bacteria identified in Cerebral spinal fluid by Culture
17
17
10.46
15.03
2.9
1.1
—
—
—
0
0
(3016018) Differential panel - Cerebral spinal fluid
15
13
12.01
14.51
1.4
1.0
—
—
—
0
0
(3016543) Leukocytes [#/volume] in Cerebral spinal fluid
27
53
5.44
13.38
2.3
1.2
e6/l
26.2
3.0
0.93
22
43
(3027475) Erythrocytes [#/volume] in Cerebral spinal fluid
27
53
5.44
13.38
2.3
1.3
e6/l
949.4
327.4
0.36
22
43
(3003458) Phosphate [Moles/volume] in Serum or Plasma
76
325
2.71
12.11
9.0
5.5
mmol/l
1.0
1.0
0.57
71
297
(3020891) Body temperature
34
92
3.98
11.42
13.6
4.8
—
—
—
0
0
(3003396) Base excess in Arterial blood by calculation
67
302
2.51
9.46
11.3
8.0
mmol/l
1.6
1.3
0.18
55
237
(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma
170
1171
1.88
7.66
12.0
5.7
mmol/l
1.2
1.2
2.68
156
1057
(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing
12
18
6.87
7.65
1.3
1.0
—
—
—
0
0
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
180
1282
1.83
7.12
10.6
6.5
mmol/l
1.2
1.2
1.37
153
1084
(3022217) INR in Platelet poor plasma by Coagulation assay
66
335
2.19
7.01
29.1
23.8
inr
1.4
1.4
—
8
43
(3019060) Gas panel - Arterial blood
42
174
2.61
7.00
11.8
7.1
—
—
—
0
0
(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method
24
77
3.27
6.29
4.7
2.4
%
89.0
91.4
0.17
24
71
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
22
67
3.44
6.25
4.5
2.6
u/ml
0.3
0.3
0.42
17
38
(3023368) Bacteria identified in Blood by Culture
113
721
1.84
6.22
5.0
4.0
—
—
—
0
0
(4027681)
11
19
5.94
6.14
1.7
1.2
—
—
—
0
0
(3026782) Osmolality of Urine
88
523
1.91
6.02
3.1
2.8
mosm/kgh2o
539.2
572.7
0.74
75
451
(3023410) Appearance of Cerebral spinal fluid
13
27
4.96
6.02
1.5
1.3
—
—
—
0
0
(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma
125
834
1.77
5.88
2.6
2.4
u/l
57.9
56.9
0.09
116
773
(3013826) Glucose [Moles/volume] in Serum or Plasma
201
1534
1.73
5.83
8.2
4.5
mmol/l
6.9
6.7
0.57
193
1422
(3037121) Protein [Mass/volume] in Urine
26
92
2.97
5.81
1.8
3.1
g/l
0.5
0.2
1.07
20
33
(42870588) Differential panel, method unspecified - Blood
125
837
1.77
5.79
8.4
5.5
—
—
—
0
0
(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid
12
25
4.93
5.53
1.1
1.0
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
134
934
1.70
5.28
5.1
3.1
—
—
—
0
0
(3000991) Gas panel - Venous blood
42
202
2.23
5.06
13.5
7.3
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
112
753
1.72
4.99
4.2
2.9
—
—
—
0
0
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
81
496
1.82
4.97
4.0
3.5
ng/l
1035.4
357.8
0.31
64
402
(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid
12
28
4.40
4.86
1.0
1.0
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
9
11
8.36
4.58
1.2
1.1
—
—
—
0
0
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
34
157
2.29
4.51
1.7
1.4
—
—
—
0
0
(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid
12
30
4.11
4.47
1.0
1.0
—
—
—
0
0
(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay
15
45
3.44
4.37
1.3
1.3
—
—
—
0
0
(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay
15
45
3.44
4.37
1.3
1.3
—
—
—
0
0
(3032080) INR in Blood by Coagulation assay
142
1044
1.60
4.36
11.0
8.7
inr
1.2
1.3
0.08
35
283
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
91
599
1.70
4.31
3.6
2.3
—
—
—
0
0
(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum
18
62
3.01
4.23
1.5
1.2
—
—
—
0
0
(3019309) Folate [Moles/volume] in Red Blood Cells
78
496
1.74
4.17
1.9
1.7
nmol/l
1147.5
1149.9
0.01
64
380
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
20
74
2.81
4.16
1.4
1.2
—
—
—
0
0
(3033386) Bacteria [Presence] in Cerebral spinal fluid by Light microscopy
7
7
10.17
4.02
1.7
1.0
—
—
—
0
0
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
86
567
1.68
4.02
2.5
1.7
mg/l
1.6
1.2
0.75
71
441
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
70
436
1.76
4.01
1.9
1.8
—
—
—
0
0
(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma
177
1389
1.55
4.00
8.1
6.4
umol/l
11.1
11.3
0.09
170
1314
(3002582) Erythrocytes [#/volume] in Urine
114
810
1.60
3.96
4.2
3.1
e6/l
17.8
164.2
1.14
94
626
(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay
12
33
3.73
3.95
1.2
1.1
—
—
—
0
0
(3000850) Epithelial cells [#/volume] in Urine
83
548
1.67
3.85
2.7
2.5
e6/l
6.6
5.2
0.28
75
490
(3008733) Herpes simplex virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
7
8
8.90
3.79
1.1
1.0
—
—
—
0
0
(3042733) HLA Ab [Presence] in Serum
6
5
12.17
3.77
5.2
4.4
—
—
—
0
0
(3024561) Albumin [Mass/volume] in Serum or Plasma
147
1120
1.54
3.72
7.6
4.5
g/l
33.6
35.4
2.95
135
1048
(3027529) Toxoplasma gondii IgM Ab [Units/volume] in Serum
9
17
5.40
3.53
1.2
1.2
—
—
—
0
0
(3022250) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Lactate to pyruvate reaction
49
285
1.84
3.52
5.6
3.8
u/l
298.7
234.1
0.48
44
271
(21494755) Public health laboratory ask at order entry panel
9
254
0.34
3.47
1.1
1.3
—
—
—
0
0
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
7
225
0.30
3.46
1.7
1.8
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
52
310
1.80
3.45
1.7
1.7
—
—
—
0
0
(3017766) Complement C4 [Mass/volume] in Serum or Plasma
20
82
2.53
3.45
2.0
1.6
g/l
0.2
0.2
0.23
20
82
(3018095) Leukocytes [#/volume] in Urine
125
932
1.53
3.44
5.6
3.6
e6/l
34.7
88.2
1.45
97
665
(3044640) Blood type and Crossmatch panel - Blood
111
809
1.54
3.38
4.2
2.4
—
—
—
0
0
(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection
10
27
3.78
3.37
1.8
1.8
—
—
—
0
0
(3016244) Insulin [Units/volume] in Serum or Plasma
8
14
5.82
3.36
3.3
2.9
mu/l
44.0
13.7
—
8
14
(3030467) Casts [#/volume] in Urine by Automated count
102
731
1.56
3.34
4.3
3.0
e6/l
0.3
0.4
0.51
84
548
(36304419) Bacteria [Presence] in Urine
99
707
1.56
3.29
4.2
2.9
—
—
—
0
0
(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum
9
19
4.83
3.26
2.4
2.2
—
—
—
0
0
(40758558) Short blood count panel - Blood
92
649
1.57
3.22
11.8
6.5
—
—
—
0
0
(3014148) Varicella zoster virus Ab [Titer] in Serum
10
28
3.65
3.22
1.2
1.1
—
—
—
0
0
(3000620) Complement C3 [Mass/volume] in Serum or Plasma
20
85
2.43
3.21
2.0
1.6
g/l
1.1
1.2
0.56
20
85
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
51
311
1.75
3.14
1.8
1.7
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
51
312
1.74
3.10
2.3
1.6
—
—
—
0
0
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
64
419
1.65
3.04
4.5
2.9
e6/l
1.6
2.1
0.43
38
231
(3005757) Coagulation factor V activity actual/normal in Platelet poor plasma by Coagulation assay
5
5
10.12
2.98
14.0
1.0
%
84.8
99.8
—
5
5
(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma
27
136
2.07
2.94
2.4
3.4
pmol/l
4.0
4.5
1.16
22
120
(46235355) HIV 1 and 2 tests - Meaningful Use set
61
400
1.64
2.88
2.1
1.7
—
—
—
0
0
(3012544) pH of Venous blood
42
250
1.77
2.81
8.3
3.5
—
—
—
0
0
(21493690) Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood
8
18
4.52
2.81
2.3
2.2
—
—
—
0
0
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
43
258
1.76
2.80
3.2
3.5
—
—
—
0
0
(3013005) Retinol [Moles/volume] in Serum or Plasma
5
6
8.43
2.76
3.4
1.8
umol/l
1.7
2.1
—
5
6
(3027945) Reticulocytes/100 erythrocytes in Blood
48
300
1.70
2.71
3.5
2.5
%
1.6
1.8
0.48
37
281
(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection
10
32
3.19
2.66
1.8
1.7
—
—
—
0
0
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
29
157
1.92
2.61
1.4
1.7
—
—
—
0
0
(3044355) Beta 2 glycoprotein 1 IgG Ab [Units/volume] in Serum or Plasma by Immunoassay
11
38
2.96
2.60
1.4
1.3
u/ml
2.2
1.4
—
5
13
(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma
90
661
1.49
2.57
2.7
2.0
mg/l
3.4
3.2
0.29
83
564
(40760888) Immunoglobulin light chains.free panel - Serum
13
50
2.66
2.56
1.2
3.5
—
—
—
0
0
(3006315) Basophils [#/volume] in Blood
158
1290
1.41
2.56
8.8
5.5
e9/l
0.0
0.0
0.07
141
1131
(3001604) Monocytes [#/volume] in Blood
157
1283
1.40
2.52
8.8
5.5
e9/l
0.6
0.6
0.03
141
1118
(3012516) Albumin [Mass/volume] in Urine
99
746
1.46
2.48
3.4
3.2
mg/l
77.7
317.8
0.96
63
495
(3018418) pH of Serum or Plasma
102
774
1.45
2.46
5.9
3.7
ph
7.4
7.4
0.99
26
137
(37020957) Sapovirus genogroups I+II+IV+V RNA [Presence] in Stool by NAA with probe detection
6
12
5.07
2.41
1.8
1.5
—
—
—
0
0
(42869457) Rotavirus RNA [Identifier] in Stool by NAA with probe detection
6
12
5.07
2.41
1.8
1.5
—
—
—
0
0
(3046896) Herpes virus 6 DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
6
12
5.07
2.41
1.2
1.1
—
—
—
0
0
(3045142) Bone marrow Pathology biopsy report
9
27
3.39
2.41
1.2
1.1
—
—
—
0
0
(3022096) Basophils/100 leukocytes in Blood
144
1173
1.39
2.30
9.8
5.7
%
0.7
0.7
0.04
135
1101
(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma
12
47
2.61
2.29
2.2
1.5
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
68
925
0.67
2.28
3.0
2.8
—
—
—
0
0
(3006504) Eosinophils/100 leukocytes in Blood
148
1213
1.38
2.27
9.6
5.6
%
2.9
2.8
0.14
138
1133
(3019069) Monocytes/100 leukocytes in Blood
149
1223
1.38
2.27
9.8
5.9
%
8.8
8.7
0.25
139
1152
(3019601) Blood group antibody investigation [Interpretation] in Plasma or RBC
7
18
3.94
2.26
1.4
1.4
—
—
—
0
0
(3016417) Amylase.pancreatic [Enzymatic activity/volume] in Serum or Plasma
37
227
1.70
2.25
1.6
2.5
u/l
30.1
32.5
0.29
32
187
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
16
73
2.25
2.24
1.6
1.6
—
—
—
0
0
(3026389) Candida sp identified in Specimen by Organism specific culture
9
29
3.16
2.24
1.1
1.1
—
—
—
0
0
(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum
27
151
1.85
2.23
1.1
1.3
—
47.4
—
0
9
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
147
1207
1.37
2.22
5.6
4.2
—
—
—
0
0
(3000067) Parathyrin.intact [Mass/volume] in Serum or Plasma
32
190
1.75
2.19
8.6
3.8
ng/l
101.3
84.5
0.40
26
165
(3013115) Eosinophils [#/volume] in Blood
161
1348
1.36
2.13
9.6
5.7
e9/l
0.2
0.2
0.11
148
1197
(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum
29
169
1.78
2.11
2.0
2.5
—
12.8
—
0
9
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
127
1025
1.37
2.11
4.0
3.6
ng/l
43.5
41.4
0.04
97
694
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
231
2550
0.72
2.11
4.8
4.3
mmol/l
1.4
1.5
0.98
207
2352
(4062490)
8
25
3.25
2.10
1.3
1.2
—
—
—
0
0
(3021197) Magnesium Ionized [Moles/volume] in Serum or Plasma
5
10
5.05
2.07
4.8
2.1
—
—
—
0
0
(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
13
56
2.37
2.07
1.7
1.6
—
—
—
0
0
(3023601) Vancomycin resistant enterococcus [Presence] in Specimen by Organism specific culture
7
20
3.55
2.06
1.9
1.8
—
—
—
0
0
(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection
12
50
2.45
2.04
1.1
1.6
—
—
—
0
0
(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells
15
70
2.19
2.01
2.1
1.8
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
56
392
1.51
2.01
2.4
2.0
—
—
—
0
0
(3037522) Nuclear Ab [Titer] in Serum
49
334
1.54
1.98
1.6
1.3
titre
443.6
517.1
0.18
11
82
(3009508) Creatinine [Moles/volume] in Urine
101
793
1.38
1.97
3.8
3.1
mmol/l
6.6
7.7
1.80
84
664
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
31
189
1.70
1.95
2.0
1.5
—
—
—
0
0
(37021247) Adenovirus 40+41 DNA [Presence] in Stool by NAA with probe detection
5
11
4.59
1.94
1.4
1.5
—
—
—
0
0
(37020445) Astrovirus RNA [Presence] in Stool by NAA with probe detection
5
11
4.59
1.94
1.4
1.5
—
—
—
0
0
(44790047)
9
33
2.77
1.94
1.2
1.4
—
—
—
0
0
(44790049)
9
33
2.77
1.94
1.2
1.4
—
—
—
0
0
(44790048)
9
33
2.77
1.94
1.2
1.4
—
—
—
0
0
(44806118)
9
33
2.77
1.94
1.2
1.4
—
—
—
0
0
(40758897) Direct antiglobulin test.IgG specific reagent [Presence] on Red Blood Cells
6
16
3.80
1.94
2.0
1.9
—
—
—
0
0
(40758895) Direct antiglobulin test.complement C3d specific reagent [Presence] on Red Blood Cells
6
16
3.80
1.94
2.0
1.9
—
—
—
0
0
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
224
2472
0.74
1.92
4.5
3.9
mmol/l
1.3
1.3
0.40
201
2271
(3019198) Lymphocytes [#/volume] in Blood
156
1316
1.33
1.90
8.8
5.7
e9/l
1.8
1.9
0.74
143
1181
(3009340) Metanephrine [Moles/volume] in Serum or Plasma
8
28
2.90
1.87
1.1
1.3
nmol/l
—
—
—
0
0
(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection
11
46
2.44
1.87
1.1
1.5
—
—
—
0
0
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
62
450
1.46
1.87
4.3
2.7
e6/l
0.5
1.0
1.98
37
260
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
18
94
1.96
1.83
1.3
1.9
—
—
—
0
0
(3002030) Lymphocytes/100 leukocytes in Blood
149
1255
1.33
1.82
9.9
5.8
%
27.3
27.5
0.10
138
1173
(3020630) Protein [Mass/volume] in Serum or Plasma
32
201
1.65
1.82
1.3
2.3
g/l
63.4
67.0
1.30
26
179
(3000093) Morphology [Interpretation] in Blood Narrative
7
23
3.08
1.81
1.1
1.1
—
—
—
0
0
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
241
2622
0.74
1.79
5.3
4.8
mmol/l
2.6
2.7
1.02
218
2416
(1001509) Gas and Carbon monoxide and Electrolytes panel - Arterial blood
6
18
3.37
1.75
1.3
1.8
—
—
—
0
0
(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection
9
36
2.54
1.75
1.1
1.6
—
—
—
0
0
(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma
125
1032
1.33
1.74
3.3
2.2
nmol/l
71.0
77.1
2.16
113
922
(3013650) Neutrophils [#/volume] in Blood by Automated count
175
1515
1.31
1.73
12.2
9.2
e9/l
4.4
4.2
0.74
162
1325
(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma
8
30
2.70
1.73
1.0
1.3
—
—
—
0
0
(3026179) Normetanephrine [Moles/volume] in Serum or Plasma
8
30
2.70
1.73
1.1
1.3
nmol/l
0.8
0.5
—
8
25
(3023420) DNA double strand Ab [Units/volume] in Serum
8
30
2.70
1.73
1.8
1.5
—
—
—
0
0
(3000963) Hemoglobin [Mass/volume] in Blood
275
2929
0.72
1.73
33.6
20.6
g/l
131.6
135.8
4.25
268
2882
(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection
5
13
3.88
1.72
1.0
1.5
—
—
—
0
0
(3018010) Neutrophils/100 leukocytes in Blood
146
1234
1.31
1.72
10.2
5.6
%
57.8
57.6
0.06
137
1160
(3028026) IgM [Mass/volume] in Serum or Plasma
26
157
1.71
1.71
2.0
1.9
g/l
1.1
2.0
1.03
26
145
(3010813) Leukocytes [#/volume] in Blood
275
2928
0.72
1.71
33.3
20.6
e9/l
7.2
6.7
2.66
263
2839
(3026361) Erythrocytes [#/volume] in Blood
275
2928
0.72
1.71
33.4
20.5
e12/l
4.4
4.5
3.21
262
2841
(3035941) MCH [Entitic mass]
275
2928
0.72
1.71
33.1
20.4
pg
30.3
30.3
0.01
268
2883
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
23
134
1.77
1.71
10.5
11.9
—
—
—
0
0
(3024731) MCV [Entitic volume]
275
2926
0.72
1.67
33.3
20.5
fl
91.0
91.1
0.02
268
2882
(4034850)
15
76
2.02
1.67
11.1
7.3
—
—
—
0
0
(3021788) Differential panel - Synovial fluid
8
31
2.62
1.67
1.5
1.6
—
—
—
0
0
(3008295) Osmolality of Serum or Plasma
6
19
3.19
1.67
1.3
1.7
mosm/kgh2o
277.5
282.1
—
6
11
(3007461) Platelets [#/volume] in Blood
275
2925
0.72
1.66
33.6
20.6
e9/l
246.8
246.1
0.05
264
2849
(3017143) Hepatitis C virus Ab [Presence] in Serum
41
281
1.52
1.64
1.8
1.5
—
—
—
0
0
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
23
136
1.74
1.63
2.3
2.4
—
—
—
0
0
(3023939) Sjogrens syndrome-A extractable nuclear Ab [Units/volume] in Serum
12
56
2.18
1.63
1.1
1.3
—
10.0
—
0
5
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
124
1031
1.31
1.63
2.6
2.0
pmol/l
92.3
94.2
0.18
77
539
(3007847) Interleukin 2 Receptor Soluble [Units/volume] in Serum or Plasma
5
14
3.61
1.62
1.2
2.1
u/ml
833.8
864.2
—
5
14
(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain
6
20
3.03
1.58
1.7
1.3
—
—
—
0
0
(3009542) Hematocrit [Volume Fraction] of Blood
220
2409
0.77
1.58
26.6
15.0
%
38.7
39.8
0.99
130
1754
(3005322) IgE [Units/volume] in Serum or Plasma
24
146
1.69
1.55
1.5
1.2
u/ml
785.1
253.9
0.39
24
130
(3007080) Epstein Barr virus nuclear IgG Ab [Units/volume] in Serum
10
44
2.31
1.54
1.2
1.1
u/ml
342.6
242.0
—
10
25
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
237
2567
0.76
1.54
4.7
4.3
mmol/l
4.4
4.6
2.18
214
2385
(40761511) CBC panel - Blood by Automated count
258
2761
0.75
1.52
21.8
13.2
—
—
—
0
0
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
14
72
1.98
1.51
1.5
1.2
—
—
—
0
0
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
13
65
2.04
1.50
1.7
1.5
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
74
578
1.36
1.47
5.5
3.5
—
—
—
0
0
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
14
73
1.96
1.46
1.7
1.6
—
—
—
0
0
(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay
6
22
2.76
1.44
1.3
1.2
—
—
—
0
0
(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing
10
46
2.21
1.41
2.0
1.4
—
—
—
0
0
(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay
10
46
2.21
1.41
1.2
1.2
—
—
—
0
0
(3007778) Kappa light chains/Lambda light chains [Mass Ratio] in Serum
14
74
1.93
1.41
1.2
2.8
—
1.5
—
0
7
(3021960) Folate [Moles/volume] in Serum or Plasma
76
601
1.34
1.40
1.8
1.6
nmol/l
19.1
20.6
0.42
64
514
(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay
6
23
2.64
1.37
1.0
1.0
—
—
—
0
0
(3020682) Albumin/Creatinine [Ratio] in Urine
97
797
1.30
1.36
4.4
3.9
mg/mmol
28.5
10.1
0.86
62
518
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
225
2438
0.79
1.35
20.4
12.9
ml/min/173m2
84.9
80.1
2.59
188
2003
(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay
12
61
2.00
1.34
1.2
1.2
—
—
—
0
0
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
12
216
0.54
1.29
2.1
1.3
—
—
—
0
0
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
17
99
1.75
1.29
1.9
1.9
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
84
682
1.30
1.29
1.4
1.4
—
—
—
0
0
(3042810) Amyloid beta 42 peptide [Mass/volume] in Cerebral spinal fluid
5
18
2.80
1.29
1.0
1.0
ng/l
805.2
540.0
—
5
11
(3000242) Tau protein [Mass/volume] in Cerebral spinal fluid
5
18
2.80
1.29
1.0
1.0
ng/l
5341.0
252.0
—
5
11
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
18
107
1.72
1.28
2.2
2.1
—
—
—
0
0
(43055554) Base excess.100% oxygenated [Moles/volume] standard in Capillary blood by calculation
27
179
1.55
1.28
5.4
3.6
mmol/l
2.0
2.1
0.04
19
134
(3028707) Methadone [Presence] in Urine by Screen method
8
35
2.31
1.27
4.3
1.9
—
—
—
0
0
(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability
8
36
2.25
1.25
1.6
1.3
—
—
—
0
0
(3029937) Albumin [Presence] in Urine by Test strip
81
660
1.30
1.21
5.0
3.8
estimate
0.0
0.0
0.50
21
212
(3021879) Hepatitis B virus core Ab [Presence] in Serum
26
174
1.53
1.19
1.4
1.4
—
—
—
0
0
(3004588) Protein electrophoresis panel - Serum or Plasma
24
158
1.56
1.18
1.5
2.2
—
—
—
0
0
(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma
222
2037
1.24
1.18
9.9
7.5
u/l
76.7
78.3
0.27
210
1894
(3048929) Epstein Barr virus Ab [Presence] in Serum
13
72
1.84
1.16
1.2
1.2
—
—
—
0
0
(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma
8
39
2.08
1.16
1.9
1.4
—
—
—
0
0
(3003740) Influenza virus B Ag [Presence] in Specimen
0
35
0.00
1.15
0.0
1.1
—
—
—
0
0
(3002523) Influenza virus A Ag [Presence] in Specimen
0
35
0.00
1.15
0.0
1.1
—
—
—
0
0
(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma
82
984
0.78
1.15
4.2
4.9
ug/l
1.9
2.7
1.16
71
873
(3027238) Thyroperoxidase Ab [Units/volume] in Serum or Plasma
23
151
1.56
1.15
1.3
1.2
iu/ml
47.1
142.0
—
6
63
(3052851) Hemolysis interference index of Serum or Plasma
14
80
1.78
1.14
4.9
3.3
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
45
340
1.37
1.12
2.0
1.6
—
—
—
0
0
(3019225) pH of Specimen
33
236
1.44
1.11
5.4
4.0
—
—
—
0
0
(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma
42
314
1.38
1.11
8.6
2.4
umol/l
8.8
8.5
0.03
35
275
(40761535) Cells panel - Urine sediment
30
211
1.46
1.10
6.4
3.1
—
—
—
0
0
(40766048) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum by Immunoassay
5
21
2.40
1.09
1.0
1.1
—
—
—
0
0
(3021589) Normoblasts [#/volume] in Blood
129
1128
1.23
1.05
12.5
9.3
e9/l
0.0
0.0
0.52
110
920
(1616796) Gas panel - Central venous blood
11
60
1.86
1.04
3.9
4.2
—
—
—
0
0
(3008757) Leukocyte morphology finding [Identifier] in Blood
7
34
2.08
1.03
2.7
3.2
—
—
—
0
0
(3001019) Free T4 and TSH panel - Serum or Plasma
5
109
0.45
1.02
3.8
1.8
—
—
—
0
0
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
20
131
1.56
1.02
4.0
2.5
%
1.0
1.4
1.21
20
131
(40763571) Iron/Transferrin [Ratio] in Serum or Plasma
47
364
1.34
1.01
3.7
2.4
%
21.6
23.8
0.61
40
316
(3037467) Urinalysis macro (dipstick) panel - Urine
196
1793
1.21
1.00
5.8
4.1
—
—
—
0
0
(3037756) Immunofixation for Serum or Plasma
9
49
1.86
0.99
1.1
1.6
—
—
—
0
0
(3032035) Polymorphonuclear cells/100 leukocytes in Blood
9
49
1.86
0.99
1.6
4.2
%
57.0
56.4
—
9
49
(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay
10
54
1.88
0.97
1.2
1.3
—
—
—
0
0
(3011288) Drugs identified in Urine by Screen method
9
50
1.82
0.97
6.7
2.2
—
—
—
0
0
(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum
9
51
1.78
0.95
1.3
1.2
—
—
—
0
0
(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma
45
567
0.76
0.92
3.0
3.0
ug/l
1.1
0.8
0.30
35
371
(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection
15
94
1.62
0.92
2.0
1.7
—
—
—
0
0
(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight
6
28
2.16
0.92
1.2
1.3
—
—
—
0
0
(3015377) Calcium [Moles/volume] in Serum or Plasma
100
863
1.22
0.91
3.6
3.4
mmol/l
2.3
2.3
0.60
86
752
(3017817) Protein [Mass] in Urine collected for unspecified duration
6
29
2.09
0.89
1.7
2.1
—
—
—
0
0
(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection
6
30
2.02
0.87
1.0
1.5
—
—
—
0
0
(3000570) Elastase.pancreatic [Mass/mass] in Stool
12
72
1.69
0.86
1.4
1.4
ug/g
267.4
333.2
—
7
38
(3035637) Corticotropin [Mass/volume] in Plasma
6
31
1.95
0.85
2.5
1.3
—
—
—
0
0
(3022313) Gas panel - Capillary blood
21
146
1.47
0.84
7.3
3.6
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
43
339
1.31
0.84
1.8
1.5
—
—
—
0
0
(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection
8
46
1.76
0.83
1.1
1.6
—
—
—
0
0
(3030905) Polymorphonuclear cells [#/volume] in Blood
8
47
1.72
0.81
1.4
3.6
e9/l
4.5
4.7
—
8
47
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
228
2414
0.84
0.80
6.6
5.8
mmol/mol
41.0
40.0
0.65
209
2247
(3015171) Extractable nuclear Ab [Units/volume] in Serum
15
98
1.55
0.80
1.3
1.2
—
3.3
—
0
8
(3004616) Nuclear Ab [Presence] in Serum
6
33
1.83
0.79
1.2
1.2
—
—
—
0
0
(3044941) Cell count panel - Synovial fluid
6
33
1.83
0.79
2.2
1.5
—
—
—
0
0
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
16
233
0.67
0.79
3.1
1.8
—
—
—
0
0
(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay
0
26
0.00
0.78
0.0
3.1
—
59.7
—
0
26
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
14
209
0.66
0.78
3.2
1.6
—
—
—
0
0
(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay
10
59
1.72
0.76
1.0
1.1
—
—
—
0
0
(3035350) Ketones [Presence] in Urine by Test strip
139
1257
1.18
0.75
4.9
3.6
estimate
0.0
0.0
0.00
26
221
(3038026) Centromere Ab [Units/volume] in Serum
5
24
2.10
0.75
1.0
1.1
—
—
—
0
0
(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma
267
2782
0.83
0.74
15.0
10.2
u/l
26.6
26.4
0.06
255
2677
(3001122) Ferritin [Mass/volume] in Serum or Plasma
124
1113
1.18
0.73
3.6
2.6
ug/l
119.5
144.5
0.59
113
1029
(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma
63
531
1.23
0.73
1.7
1.8
pmol/l
455.3
415.6
0.48
52
456
(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence
5
25
2.01
0.73
1.8
1.2
—
—
—
0
0
(3013327) Hepatitis A virus IgM Ab [Presence] in Serum
7
39
1.81
0.73
1.0
1.1
—
—
—
0
0
(3006418) Campylobacter sp identified in Tissue by Organism specific culture
12
76
1.60
0.72
1.1
1.2
—
—
—
0
0
(3014765) Yersinia sp identified in Stool by Organism specific culture
12
76
1.60
0.72
1.1
1.2
—
—
—
0
0
(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay
14
93
1.53
0.70
2.4
2.0
—
—
—
0
0
(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection
7
41
1.72
0.70
1.0
1.6
—
—
—
0
0
(40762485) Glomerular basement membrane Ab [Units/volume] in Serum by Immunoassay
5
27
1.86
0.68
1.4
1.1
—
—
—
0
0
(21494434) Karyotype in Bone marrow
5
27
1.86
0.68
1.6
1.1
—
—
—
0
0
(3027544) Mycobacterium sp identified in Sputum by Organism specific culture
5
27
1.86
0.68
5.0
5.2
—
—
—
0
0
(3022145) Colonoscopy Study observation
22
293
0.73
0.68
1.8
1.3
—
—
—
0
0
(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection
5
28
1.80
0.66
2.4
1.6
—
—
—
0
0
(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection
5
28
1.80
0.66
2.4
1.6
—
—
—
0
0
(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection
5
28
1.80
0.66
2.4
1.6
—
—
—
0
0
(42529406) Shigella sp [Presence] in Stool by Culture
12
78
1.56
0.66
1.1
1.2
—
—
—
0
0
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
202
1894
1.16
0.66
4.8
3.8
pmol/l
14.7
14.8
0.21
182
1709
(3050238) Crystals [Presence] in Synovial fluid by Light microscopy
10
62
1.63
0.65
1.7
1.2
—
—
—
0
0
(3025839) Triglyceride [Moles/volume] in Serum or Plasma
60
701
0.83
0.65
1.4
1.6
mmol/l
1.6
1.4
0.79
50
601
(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot
5
29
1.73
0.64
1.0
1.1
—
—
—
0
0
(40759836) Histone Ab [Presence] in Serum by Immunoblot
5
29
1.73
0.64
1.0
1.1
—
—
—
0
0
(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot
5
29
1.73
0.64
1.0
1.1
—
—
—
0
0
(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot
5
29
1.73
0.64
1.0
1.1
—
—
—
0
0
(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot
5
29
1.73
0.64
1.0
1.1
—
—
—
0
0
(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot
5
29
1.73
0.64
1.0
1.1
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
26
200
1.32
0.62
2.3
3.7
—
—
—
0
0
(3040151) Glucose [Moles/volume] in Capillary blood
5
30
1.68
0.61
1.0
9.4
mmol/l
6.8
6.4
—
5
23
(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma
56
476
1.21
0.61
3.7
2.8
mmol/l
2.5
2.4
0.07
47
418
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
68
779
0.84
0.60
4.3
4.4
%
22.9
21.4
0.29
28
377
(3020876) Protein [Mass/time] in 24 hour Urine
0
21
0.00
0.60
0.0
1.9
—
—
—
0
0
(4024509)
0
22
0.00
0.59
0.0
1.3
—
—
—
0
0
(3000492) Spirometry study
18
241
0.73
0.59
1.4
1.5
—
—
—
0
0
(4306422)
6
35
1.73
0.58
1.5
1.3
—
—
—
0
0
(3019150) Specific gravity of Urine by Refractometry
66
574
1.18
0.57
6.2
3.7
kg/l
1.0
1.0
0.15
11
84
(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence
6
37
1.63
0.56
1.0
1.1
—
—
—
0
0
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
37
305
1.24
0.54
10.0
6.6
—
—
—
0
0
(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma
185
1740
1.13
0.54
5.5
3.0
u/l
62.7
47.3
0.53
170
1635
(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma
87
779
1.16
0.53
2.5
3.1
ng/l
1409.5
1544.2
0.12
74
669
(1001926) Buprenorphine [Presence] in Urine by Screen method
9
63
1.44
0.52
4.3
1.6
—
—
—
0
0
(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection
6
40
1.51
0.52
1.2
1.7
—
—
—
0
0
(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay
6
40
1.51
0.52
1.3
1.6
—
—
—
0
0
(3021601) Nitrite [Presence] in Urine by Test strip
137
1268
1.13
0.51
6.7
5.0
estimate
0.0
0.0
0.00
24
222
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
148
1585
0.89
0.51
2.7
3.0
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
65
571
1.17
0.50
4.1
5.2
—
—
—
0
0
(3002385) Erythrocyte distribution width [Ratio]
210
2201
0.89
0.50
27.4
17.2
%
13.9
13.7
0.81
204
2152
(3017446) Testosterone [Moles/volume] in Serum or Plasma
17
222
0.75
0.49
1.7
2.0
nmol/l
11.2
13.1
—
10
205
(3009261) Glucose [Presence] in Urine by Test strip
138
1283
1.12
0.48
4.9
3.6
estimate
0.0
0.0
0.00
24
207
(3030366) Cystatin C [Mass/volume] in Serum or Plasma
12
85
1.43
0.47
14.2
3.3
mg/l
1.4
1.6
0.43
12
78
(3007164) IgA [Mass/volume] in Serum or Plasma
58
508
1.17
0.47
1.8
1.4
g/l
2.0
2.5
2.25
40
309
(3042111) Morphology [Interpretation] in Bone marrow Narrative
7
48
1.47
0.47
1.6
1.6
—
—
—
0
0
(3004716) Salmonella sp identified in Stool by Organism specific culture
16
120
1.35
0.47
1.2
1.3
—
—
—
0
0
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
21
264
0.78
0.46
2.0
1.6
—
—
—
0
0
(3016650) Hepatitis A virus Ab [Presence] in Serum
7
51
1.38
0.44
1.0
1.1
—
—
—
0
0
(3043109) Cytology report of Tissue fine needle aspirate Cyto stain
8
57
1.41
0.42
1.5
1.4
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
23
186
1.25
0.41
1.8
1.5
—
—
—
0
0
(3015024) Glucose [Moles/volume] in Serum or Plasma --1 hour post dose glucose
0
15
0.00
0.41
0.0
1.9
—
6.3
—
0
8
(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
(3012568) Campylobacter sp identified in Specimen by Organism specific culture
5
34
1.48
0.40
2.8
1.6
—
—
—
0
0
(3023419) Bacteria identified in Sputum by Culture
5
34
1.48
0.40
3.6
3.1
—
—
—
0
0
(3016750) Collection duration of Urine
0
18
0.00
0.40
0.0
2.8
—
507.1
—
0
12
(3044889) 12 lead EKG panel
172
1808
0.90
0.40
4.2
3.8
—
—
—
0
0
(3038177) Helicobacter pylori Ab [Presence] in Serum
5
35
1.43
0.39
1.2
1.2
—
—
—
0
0
(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma
5
35
1.43
0.39
1.6
1.5
ug/l
16.1
16.8
—
5
35
(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma
32
271
1.20
0.39
2.5
1.8
%
1.5
1.5
0.11
27
246
(4010399)
22
179
1.24
0.38
1.3
1.4
—
—
—
0
0
(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method
5
37
1.36
0.37
1.6
1.2
—
—
—
0
0
(3025130) Human papilloma virus identified in Specimen
5
37
1.36
0.37
2.6
1.8
—
—
—
0
0
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
9
70
1.29
0.37
1.0
1.3
—
—
—
0
0
(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma
6
43
1.40
0.35
1.2
3.0
—
—
—
0
0
(3041354) Potassium [Moles/volume] in Venous blood
6
44
1.37
0.34
2.0
2.9
mmol/l
3.8
4.1
—
6
44
(3035285) Chloride [Moles/volume] in Venous blood
6
44
1.37
0.34
2.0
2.9
mmol/l
105.7
105.2
—
6
44
(3033705) Calcium.ionized [Moles/volume] in Venous blood
6
44
1.37
0.34
2.0
2.9
—
—
—
0
0
(3003327) Ova and parasites identified in Stool by Light microscopy
6
86
0.69
0.33
1.5
1.4
—
—
—
0
0
(3008898) HLA-B27 [Presence]
6
87
0.68
0.33
1.2
1.1
—
—
—
0
0
(3004809) Band form neutrophils/100 leukocytes in Blood
6
46
1.31
0.33
2.7
3.2
%
0.7
1.0
—
6
36
(3023150) Myeloperoxidase Ab [Units/volume] in Serum
6
47
1.28
0.32
1.0
1.5
—
—
—
0
0
(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection
7
56
1.26
0.29
2.3
1.5
—
—
—
0
0
(3013139) Helicobacter pylori Ag [Presence] in Stool
11
140
0.78
0.28
1.3
1.2
—
—
—
0
0
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
12
95
1.27
0.26
2.2
2.8
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
39
349
1.13
0.26
1.5
1.4
—
—
—
0
0
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
247
2527
0.92
0.25
4.3
4.4
mmol/l
6.1
6.0
0.30
226
2307
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
38
422
0.89
0.25
1.7
1.4
—
—
—
0
0
(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma
30
337
0.88
0.23
5.4
4.3
%
31.0
31.6
0.09
22
231
(3016879) Cocaine [Presence] in Urine
10
79
1.27
0.22
4.1
1.5
—
—
—
0
0
(3019230) Fractional oxyhemoglobin in Venous blood
5
41
1.22
0.22
3.2
1.7
%
76.3
59.4
—
5
41
(4035726)
25
220
1.15
0.22
1.5
1.4
—
—
—
0
0
(3006462) Nitrate [Presence] in Urine
0
11
0.00
0.21
0.0
4.5
—
—
—
0
0
(3037556) Urate [Mass/volume] in Serum or Plasma
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
(36306090) Helicobacter pylori [Presence] in Tissue by Organism specific culture
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
(3010838) Calcium [Moles/time] in 24 hour Urine
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
(4211845)
0
13
0.00
0.21
0.0
3.9
—
—
—
0
0
(3015183) Erythrocyte sedimentation rate
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
(3028626) Oxygen [Partial pressure] in Capillary blood
10
80
1.26
0.20
7.2
2.7
kpa
9.1
8.2
—
10
72
(3000012) Reticulocyte production index
0
14
0.00
0.20
0.0
2.1
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
107
1022
1.07
0.20
2.5
2.0
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
105
1006
1.06
0.18
5.1
3.7
—
—
—
0
0
(3049717) Cytology report of Urine Cyto stain
12
101
1.19
0.17
1.7
2.6
—
—
—
0
0
(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection
8
72
1.11
0.16
2.6
1.7
—
—
—
0
0
(40766189) Gliadin peptide IgG Ab [Units/volume] in Serum by Immunoassay
6
76
0.79
0.16
1.2
1.1
—
11.0
—
0
10
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
60
567
1.07
0.15
1.4
1.3
u/ml
1.1
2.0
1.02
20
153
(3023323) Follitropin [Units/volume] in Serum or Plasma
7
87
0.80
0.14
1.4
1.4
iu/l
20.3
23.5
—
7
70
(3026493) Urate [Moles/volume] in Serum or Plasma
62
652
0.94
0.14
3.8
2.6
umol/l
312.9
7634.2
3.22
52
560
(3000764) Benzodiazepines [Presence] in Urine
10
84
1.20
0.14
4.2
1.5
—
—
—
0
0
(3027008) Opiates [Presence] in Urine
10
85
1.18
0.12
4.0
1.5
—
—
—
0
0
(3028300) Cannabinoids [Presence] in Urine
10
85
1.18
0.12
4.1
1.5
—
—
—
0
0
(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma
44
418
1.06
0.10
1.2
1.3
iu/ml
23.4
34.6
0.58
14
138
(3048689) Calprotectin [Mass/mass] in Stool
32
301
1.07
0.09
1.7
2.3
ug/g
129.3
120.7
0.06
20
242
(3021901) Oxygen saturation in Capillary blood
6
54
1.11
0.09
1.8
2.5
—
—
—
0
0
(3013512) EKG study
81
786
1.04
0.09
4.4
3.8
—
—
—
0
0
(44816559) Phosphatidylethanol [Mass/volume] in Blood
6
58
1.04
0.08
2.0
1.2
—
—
—
0
0
(3024891) Influenza virus A+B Ag [Presence] in Specimen
7
66
1.06
0.08
1.1
1.1
—
—
—
0
0
(3027944) Amphetamines [Presence] in Urine
9
86
1.05
0.07
4.7
1.5
—
—
—
0
0
(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay
9
86
1.05
0.07
1.3
1.7
—
—
—
0
0
(1761482) Bacteria [#/volume] in Urine by Culture
9
87
1.04
0.07
6.1
4.6
—
—
—
0
0
(3025941) Bacteria identified in Stool by Culture
15
138
1.09
0.06
1.3
1.2
—
—
—
0
0
(3002256) Pathology report gross observation
30
315
0.95
0.06
1.6
1.3
—
—
—
0
0
(3002179) Metamyelocytes/100 leukocytes in Blood
20
187
1.07
0.06
3.9
3.9
%
0.1
0.4
—
8
54
(3045414) Leukocytes [Presence] in Urine
9
104
0.86
0.06
1.8
1.8
—
—
—
0
0
(3025159) Blasts/100 leukocytes in Blood
18
192
0.93
0.05
4.0
4.2
%
0.0
0.2
—
8
60
(3023103) Potassium [Moles/volume] in Serum or Plasma
273
2715
1.02
0.04
25.7
16.0
mmol/l
3.9
4.0
2.06
266
2633
(3017895) Helicobacter pylori Ab [Units/volume] in Serum
10
91
1.10
0.04
1.8
1.6
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
70
714
0.98
0.04
3.6
3.3
—
—
—
0
0
(3003785) Carcinoembryonic Ag [Mass/volume] in Serum or Plasma
29
279
1.04
0.04
2.8
4.3
ug/l
40.0
53.8
0.11
22
233
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
236
2346
1.02
0.03
5.8
4.5
mu/l
2.0
1.9
0.72
215
2116
(3019550) Sodium [Moles/volume] in Serum or Plasma
272
2708
1.02
0.03
26.8
15.9
mmol/l
139.5
139.7
0.46
265
2630
(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)
21
201
1.05
0.03
3.3
2.7
ml/min/173m2
65.6
62.5
—
9
88
(3000330) Specific gravity of Urine by Test strip
14
148
0.94
0.02
5.1
3.8
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
20
208
0.96
0.02
1.3
1.2
—
—
—
0
0
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
14
133
1.05
0.01
1.0
1.0
—
—
—
0
0
(3017181) Myelocytes/100 leukocytes in Blood
22
213
1.04
0.01
3.9
4.0
%
0.8
0.7
—
9
76
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
263
2637
0.99
0.01
23.2
13.9
mg/l
30.0
23.4
1.74
218
2085
(3013707) Erythrocyte sedimentation rate by Westergren method
191
1909
1.00
0.00
4.9
3.9
mm/h
12.7
12.2
0.13
177
1751
(40768443) Skin Pathology biopsy report
11
113
0.97
0.00
1.4
1.3
—
—
—
0
0
(3022621) pH of Urine by Test strip
17
173
0.98
0.00
3.9
2.9
—
—
—
0
0
(1002224) Polysomnography panel
11
105
1.05
0.00
1.0
1.1
—
—
—
0
0
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
41
405
1.01
0.00
1.2
1.3
u/ml
1.4
14.6
—
9
153
(40768797) Stomach Pathology biopsy report
36
356
1.01
0.00
1.2
1.2
—
—
—
0
0
(3000213) Normetanephrine [Moles/time] in 24 hour Urine
0
5
0.00
0.00
0.0
1.4
—
1.9
—
0
5
(3021440) Promyelocytes/100 leukocytes in Blood
20
200
1.00
0.00
4.0
4.1
%
0.1
0.1
—
9
67
(3021513) Carbon dioxide [Partial pressure] in Mixed venous blood
0
6
0.00
0.00
0.0
7.8
—
—
—
0
0
(3042299) inFLIXimab [Mass/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
6.0
—
6.6
—
0
7
(3009306) Alpha-1-Fetoprotein [Mass/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
4.2
—
—
—
0
0
(3016845) Adenovirus Ag [Presence] in Specimen by Immunofluorescence
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(40765089) Chromosome analysis panel - Blood by G-banded
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3022689) Creatine [Moles/volume] in Urine
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3034037) Hematocrit [Volume Fraction] of Mixed venous blood
0
5
0.00
0.00
0.0
9.2
—
—
—
0
0
(3014891) Appearance of Pleural fluid
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3042602) Urea [Moles/volume] in Serum or Plasma --post dialysis
0
5
0.00
0.00
0.0
6.2
—
7.9
—
0
5
(3014043) Spermatozoa Nonprogressive/100 spermatozoa in Semen
0
5
0.00
0.00
0.0
8.0
—
—
—
0
0
(3015479) Mycobacterium sp identified in Blood by Organism specific culture
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3007695) Herpes simplex virus 2 IgG Ab [Presence] in Cerebral spinal fluid
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3014051) Protein [Presence] in Urine by Test strip
5
59
0.85
0.00
2.0
2.3
—
—
—
0
0
(3039602) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Capillary blood
0
6
0.00
0.00
0.0
2.0
—
1.2
—
0
6
(3034988) Calcium [Moles/volume] in Capillary blood
0
7
0.00
0.00
0.0
2.0
—
1.2
—
0
7
(3021162) Amylase [Enzymatic activity/volume] in Specimen
0
5
0.00
0.00
0.0
2.6
—
3706.6
—
0
5
(3009871) Measles virus Ab [Titer] in Serum
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3000285) Sodium [Moles/volume] in Blood
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3010254) Herpes simplex virus identified in Specimen by Organism specific culture
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3034603) RHD gene allele [Genotype] in Blood or Tissue by Molecular genetics method Nominal
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3031072) Herpes simplex virus 1 IgG Ab [Presence] in Cerebral spinal fluid
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(40761995) Spermatozoa Progressive [#/volume] in Semen
0
5
0.00
0.00
0.0
4.0
—
—
—
0
0
(4133840)
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3023659) Complement C1 esterase inhibitor.functional/Complement C1 esterase inhibitor.total in Serum or Plasma
0
7
0.00
0.00
0.0
1.1
—
121.1
—
0
7
(3005011) Chlamydia sp Ab [Titer] in Serum
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
(3011335) Digoxin [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
(3037826) lamoTRIgine [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
2.3
—
18.1
—
0
6
(3038071) Oxygen [Partial pressure] in Mixed venous blood
0
6
0.00
0.00
0.0
7.8
—
—
—
0
0
(3022192) Triglyceride [Mass/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
2.9
—
—
—
0
0
(3029715) Chromosome analysis.interphase [Interpretation] in Bone marrow by FISH Narrative
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3004446) Plasmodium sp identified in Blood by Light microscopy
0
5
0.00
0.00
0.0
3.0
—
—
—
0
0
(723474) SARS-CoV-2 (COVID-19) IgG Ab [Presence] in Serum or Plasma by Immunoassay
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection
7
74
0.94
0.00
1.3
1.4
—
—
—
0
0
(40763634) TCRG gene rearrangements [Presence] in Bone marrow by Molecular genetics method
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3051101) Glucose [Moles/volume] in Cord blood
0
7
0.00
0.00
0.0
5.3
—
—
—
0
0
(3028371) Actinomyces sp identified in Specimen by Organism specific culture
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3020650) Glucose [Presence] in Urine
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint G6_DISBROTHUNS and mortality.

Females

Parameter HR [95% CI] p-value
G6_DISBROTHUNS 3.99 [2.68, 5.94] < 0.001
Birth year 0.998 [0.99, 1.01] 0.697

During the follow-up period (1.1.1998 — 31.12.2019), 173 out of 487 females with G6_DISBROTHUNS died.

Males

Parameter HR [95% CI] p-value
G6_DISBROTHUNS 4.946 [3.66, 6.68] < 0.001
Birth year 0.99 [0.98, 1.0] 0.041

During the follow-up period (1.1.1998 — 31.12.2019), 227 out of 545 males with G6_DISBROTHUNS died.

Mortality risk

Mortality risk for people of age

years, who have G6_DISBROTHUNS.

N-year risk Females Males
1 0.44% 0.838%
5 2.171% 5.642%
10 6.164% 14.249%
15 11.626% 26.237%
20 20.3% 41.219%

Relationships between endpoints

↥

Index endpoint: G6_DISBROTHUNS – Disorders of brain, other and unspecified

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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