Disorders of puberty

E4_DISPUB

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 E30
  • Cause of death: ICD-10 E30

2 out of 7 registries used, show all original rules.

585

4. Check minimum number of events

None

585

5. Include endpoints

621

6. Filter based on genotype QC (FinnGen only)

621

Control definitions (FinnGen only)

Control exclude
E4_ENDOGLAND

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
E20-E35
Name in latin
Perturbationes pubertatis non alibi classificatae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 13514 6222 7284
Only index persons 12248 5115 7133
Unadjusted period prevalence (%)
Whole population 0.19 0.18 0.20
Only index persons 0.24 0.19 0.27
Median age at first event (years)
Whole population 12.30 9.31 14.85
Only index persons 12.72 9.74 14.86

-FinnGen-

Key figures

All Female Male
Number of individuals 621 394 227
Unadjusted period prevalence (%) 0.12 0.13 0.10
Median age at first event (years) 12.18 10.60 14.92

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
560
Matched controls
5601
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
E30.1
ICD-10 Finland
Precocious puberty
+∞
173.1
157
*
E30.09
ICD-10 Finland
Delayed puberty NOS
+∞
170.8
155
*
E30.00
ICD-10 Finland
Familial delayed puberty
2024.3
161.7
149
*
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
23.8
106.8
157
90
E30.9
ICD-10 Finland
Disorder of puberty, unspecified
+∞
79.1
74
*
E30.8
ICD-10 Finland
Other disorders of puberty
731.2
67.4
65
*
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
36.2
63.0
81
26
E34.35
ICD-10 Finland
Abnormal growth retardation
+∞
55.1
52
*
E22.80
ICD-10 Finland
Central precocious puberty
426.7
40.6
40
*
L02AE02
ATC
leuprorelin; implant, parenteral
34.2
38.6
50
16
101
Kela drug reimbursment
Anterior pituitary hypofunction
+∞
35.8
34
*
H01AC01
ATC
somatropin; parenteral
330.4
31.1
31
*
Z51.80
ICD-10 Finland
Manipulation of puberty development with hormone therapy
+∞
30.5
29
*
E34.39
ICD-10 Finland
Short stature, not elsewhere classified
114.3
20.7
22
*
2590A
ICD-9 Finland
Other endocrine disorders, Delay in sexual development and puberty, not elsewhere classified
+∞
19.9
19
*
2591A
ICD-9 Finland
Other endocrine disorders, Precocious sexual development and puberty, not elsewhere classified
+∞
19.9
19
*
E23.01
ICD-10 Finland
Isolated deficiency of growth hormone
+∞
17.8
17
*
E27.0
ICD-10 Finland
Other adrenocortical overactivity
+∞
17.8
17
*
121
Kela drug reimbursment
Severe hypofunction of sexual glands
43.5
17.4
21
5
E23.04
ICD-10 Finland
Hypogonadotropic hypogonadism
153.8
14.5
15
*
AA4CG
NOMESCO Finland
Extensive MRI examination of sella turcica with high intensity magnet
28.0
14.4
19
7
H03AA01
ATC
levothyroxine sodium; systemic
2.9
13.2
87
338
N91.0
ICD-10 Finland
Primary amenorrhoea
29.1
13.0
17
6
ZXD10
NOMESCO Finland
Scheduled procedure
2.1
12.6
179
1027
E34.30
ICD-10 Finland
Short stature NOS
+∞
12.5
12
*
E34.45
ICD-10 Finland
Abnormal growth increase
+∞
12.5
12
*
301
Kela drug reimbursment
Growth hormone
+∞
12.5
12
*
R62.8
ICD-10 Finland
Other lack of expected normal physiological development
12.0
12.4
22
19
ZXE10
NOMESCO Finland
More than one and less than three hours
2.2
12.1
153
830
G03FB08
ATC
dydrogesterone and estrogen; systemic (progestogens and estrogens, sequential prep.)
12.2
10.9
19
16
G03DB01
ATC
dydrogesterone; oral
3.5
10.6
49
148
104
Kela drug reimbursment
Thyroid insufficiency
5.5
10.4
30
57
Z3231
NOMESCO Finland
Registered nurse
1.9
10.4
175
1059
E28.2
ICD-10 Finland
Polycystic ovarian syndrome
10.3
10.1
19
19
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
4.4
10.0
36
87
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.0
9.8
141
799
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
2.9
9.7
60
223
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
3.3
9.7
48
154
E30.0
ICD-10 Finland
Delayed puberty
+∞
9.4
9
*
E23.00
ICD-10 Finland
Panhypopituitarism
+∞
9.4
9
*
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
9.7
9.3
18
19
Z3226
NOMESCO Finland
Physiotherapist
2.1
9.1
111
590
602
Kela drug reimbursment
Children's severe malnutrition
5.4
8.7
25
48
E29.1
ICD-10 Finland
Testicular hypofunction
28.0
8.5
11
*
186
Kela drug reimbursment
Growth retardation associated with renal failure (growth hormone)
91.4
8.4
9
*
R1260
NOMESCO Finland
Evaluation of communicative skills
8.0
8.4
18
23
E28.3
ICD-10 Finland
Primary ovarian failure
+∞
8.4
8
*
L02AE04
ATC
triptorelin; parenteral
+∞
8.4
8
*
H02AB09
ATC
hydrocortisone; systemic
4.1
8.3
31
79
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
2.7
8.2
55
216
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.6
8.2
61
253
7806A
ICD-9 Finland
General symptoms, Pyrexia of unknown origin
22.4
8.0
11
5
RD210
NOMESCO Finland
NA
3.4
7.9
37
115
T10
ICPC
Growth delay
18.7
7.6
11
6
T99
ICPC
Endocr/metab/nutrit disease other
12.1
7.6
13
11
XA800
NOMESCO Finland
Neuropsychological investigation
3.2
7.6
38
124
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.3
7.5
68
315
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.1
7.4
93
495
E23.02
ICD-10 Finland
Neurosecretory dysfunction of the growth hormone
+∞
7.3
7
*
ZXE00
NOMESCO Finland
One hour or less
1.7
7.1
197
1369
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.6
7.1
50
204
F82
ICD-10 Finland
Specific developmental disorder of motor function
4.7
7.0
22
48
N91.1
ICD-10 Finland
Secondary amenorrhoea
4.0
6.9
26
68
TPH04
NOMESCO Finland
Cathetrisation of vein
2.1
6.8
83
435
L04AA01
ATC
[U] ciclosporin; systemic
11.1
6.8
12
11
R62.0
ICD-10 Finland
Delayed milestone
4.0
6.8
25
64
F83
ICD-10 Finland
Mixed specific developmental disorders
4.0
6.7
25
65
WX408
NOMESCO Finland
General anesthesy, balanced
1.8
6.6
133
839
KAC00
NOMESCO Finland
Nephrectomy
70.6
6.4
7
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.0
6.2
81
441
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.9
6.2
100
586
Z2446
NOMESCO Finland
Social worker
2.0
6.1
72
376
R4110
NOMESCO Finland
Physiotherapy
1.8
6.1
106
639
RK220
NOMESCO Finland
NA
10.2
6.1
11
11

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3009214) Lutropin [Units/volume] in Serum or Plasma
151
280
6.80
82.01
3.3
1.6
u/l
5.0
5.9
0.71
119
206
(3023323) Follitropin [Units/volume] in Serum or Plasma
144
267
6.72
78.00
3.2
1.6
iu/l
8.3
9.9
0.40
118
195
(43534046) Estradiol (E2) [Moles/volume] in Serum or Plasma by High sensitivity method
58
54
11.74
54.70
2.6
1.7
nmol/l
0.1
0.2
1.03
50
41
(3017446) Testosterone [Moles/volume] in Serum or Plasma
115
284
4.74
44.05
3.5
1.7
nmol/l
6.9
12.6
8.62
102
258
(3022411) Androstenedione [Moles/volume] in Serum or Plasma
29
19
15.96
33.30
2.1
2.0
nmol/l
4.7
3.5
0.70
29
19
(3035637) Corticotropin [Mass/volume] in Plasma
32
60
5.57
16.53
1.7
1.6
—
—
—
0
0
(3015377) Calcium [Moles/volume] in Serum or Plasma
183
994
2.19
16.40
2.6
2.4
mmol/l
2.4
2.4
0.15
170
891
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
454
3594
1.98
12.62
4.7
3.6
pmol/l
14.4
14.4
0.15
426
3251
(3026725) Estradiol (E2) [Moles/volume] in Serum or Plasma
41
119
3.62
12.29
1.9
1.4
nmol/l
0.3
0.4
0.24
34
98
(3036481) Cortisol [Moles/volume] in Serum or Plasma
91
413
2.41
12.20
2.8
2.1
nmol/l
368.5
389.6
0.49
86
386
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
243
1635
1.80
10.88
9.6
7.2
mmol/l
1.2
1.2
0.55
209
1434
(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma
246
1712
1.72
9.48
3.3
2.6
nmol/l
69.6
67.3
0.68
231
1603
(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma
221
1509
1.72
9.03
9.7
7.3
mmol/l
1.2
1.2
0.16
208
1405
(3047826) Mullerian inhibiting substance [Mass/volume] in Serum or Plasma
46
176
2.74
8.73
1.6
1.4
ug/l
8.4
3.5
1.33
40
169
(3021387) Prolactin [Units/volume] in Serum or Plasma
78
384
2.18
8.57
1.7
1.4
mu/l
349.9
325.5
0.23
73
336
(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma
349
2736
1.63
8.06
7.3
5.5
u/l
93.6
84.8
1.76
329
2551
(3024561) Albumin [Mass/volume] in Serum or Plasma
194
1312
1.70
8.04
5.9
5.4
g/l
37.9
38.2
0.42
183
1219
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
488
4177
1.79
8.01
5.4
4.0
mu/l
2.1
2.1
0.03
468
3917
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
246
1777
1.64
7.86
1.5
1.6
u/ml
1.8
2.2
0.15
53
389
(3007164) IgA [Mass/volume] in Serum or Plasma
222
1574
1.64
7.59
1.6
1.5
g/l
1.9
1.9
0.04
114
900
(3018418) pH of Serum or Plasma
135
857
1.74
6.92
4.6
3.1
ph
7.4
7.4
1.01
36
165
(3023103) Potassium [Moles/volume] in Serum or Plasma
488
4261
1.68
6.47
12.5
8.5
mmol/l
3.9
3.9
0.53
469
4076
(3026782) Osmolality of Urine
125
792
1.72
6.42
3.3
2.6
mosm/kgh2o
623.6
591.2
0.61
111
678
(40765089) Chromosome analysis panel - Blood by G-banded
19
51
3.81
6.40
1.0
1.0
—
—
—
0
0
(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma
531
4751
1.81
6.37
9.5
7.2
u/l
27.5
26.2
0.46
516
4561
(36660697) Celiac disease serology panel - Serum
108
658
1.78
6.36
1.1
1.2
—
—
—
0
0
(3019550) Sodium [Moles/volume] in Serum or Plasma
487
4257
1.67
6.35
12.7
8.5
mmol/l
139.5
139.5
0.07
470
4088
(3021901) Oxygen saturation in Capillary blood
21
62
3.47
6.19
3.7
2.7
—
—
—
0
0
(3000850) Epithelial cells [#/volume] in Urine
128
829
1.69
6.04
3.7
2.5
e6/l
5.1
8.4
2.32
108
715
(43055554) Base excess.100% oxygenated [Moles/volume] standard in Capillary blood by calculation
76
427
1.89
5.79
9.6
4.8
mmol/l
1.6
1.0
0.75
54
303
(3021589) Normoblasts [#/volume] in Blood
289
2281
1.50
5.73
9.9
8.6
e9/l
0.0
0.0
0.51
235
1820
(3022313) Gas panel - Capillary blood
65
348
1.97
5.71
10.3
5.3
—
—
—
0
0
(3009343) pH of Capillary blood
76
430
1.87
5.67
9.8
4.8
ph
7.4
7.4
—
9
30
(3022096) Basophils/100 leukocytes in Blood
285
2249
1.49
5.62
8.9
7.4
%
0.6
0.6
0.35
275
2128
(3019083) Insulin-like growth factor [Moles/volume] in Serum or Plasma
9
7
13.02
5.59
2.2
2.3
—
—
—
0
0
(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma
219
1638
1.52
5.58
5.4
5.4
umol/l
10.2
10.6
0.36
206
1506
(3002385) Erythrocyte distribution width [Ratio]
501
4461
1.64
5.51
15.5
11.4
%
13.2
13.1
1.37
493
4368
(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma
17
48
3.61
5.36
2.8
5.9
—
—
—
0
0
(40758558) Short blood count panel - Blood
168
1199
1.55
5.26
7.5
7.5
—
—
—
0
0
(3030467) Casts [#/volume] in Urine by Automated count
162
1148
1.56
5.24
3.7
3.1
e6/l
0.3
0.2
0.30
123
842
(3006504) Eosinophils/100 leukocytes in Blood
291
2333
1.47
5.16
8.9
7.2
%
3.0
2.9
0.17
281
2195
(3001604) Monocytes [#/volume] in Blood
301
2430
1.46
5.14
8.6
7.2
e9/l
0.6
0.5
1.66
265
2099
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
185
1356
1.52
5.11
4.3
3.3
—
—
—
0
0
(36032269) Testosterone Free [Moles/volume] in Serum or Plasma by calculation
24
87
2.83
5.09
1.7
1.5
pmol/l
113.6
212.2
2.86
24
82
(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma
115
759
1.63
5.00
2.8
2.3
u/l
184.0
217.9
0.33
109
719
(3019198) Lymphocytes [#/volume] in Blood
314
2569
1.45
4.93
8.5
7.0
e9/l
2.1
2.0
0.46
285
2275
(3006315) Basophils [#/volume] in Blood
300
2434
1.45
4.92
8.7
7.2
e9/l
0.0
0.0
0.03
267
2103
(3032080) INR in Blood by Coagulation assay
141
981
1.57
4.91
4.3
4.5
inr
1.1
1.1
0.60
55
349
(3013650) Neutrophils [#/volume] in Blood by Automated count
330
2727
1.45
4.90
10.2
8.8
e9/l
3.7
3.8
0.11
291
2342
(3007461) Platelets [#/volume] in Blood
594
5604
2.38
4.89
17.6
13.0
e9/l
265.1
262.4
0.44
574
5424
(3023368) Bacteria identified in Blood by Culture
108
706
1.64
4.87
4.4
3.8
—
—
—
0
0
(3024731) MCV [Entitic volume]
594
5611
2.35
4.75
17.6
12.9
fl
88.0
88.0
0.02
587
5524
(3035941) MCH [Entitic mass]
594
5612
2.34
4.73
17.6
12.9
pg
29.5
29.5
0.42
587
5526
(3026361) Erythrocytes [#/volume] in Blood
594
5613
2.34
4.71
17.7
13.0
e12/l
4.6
4.6
0.91
573
5421
(3002030) Lymphocytes/100 leukocytes in Blood
305
2497
1.44
4.69
8.8
6.9
%
32.3
32.2
0.04
294
2369
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
79
481
1.74
4.64
11.8
9.2
mmol/l
25.4
24.8
0.83
79
481
(3010813) Leukocytes [#/volume] in Blood
594
5618
2.32
4.61
17.7
13.0
e9/l
6.8
6.7
0.08
574
5430
(3000963) Hemoglobin [Mass/volume] in Blood
594
5619
2.31
4.59
17.8
13.1
g/l
135.1
136.5
1.75
587
5534
(3019069) Monocytes/100 leukocytes in Blood
289
2352
1.43
4.54
9.5
7.3
%
8.3
8.1
1.00
277
2227
(42870588) Differential panel, method unspecified - Blood
215
1657
1.46
4.54
8.6
7.5
—
—
—
0
0
(3016228) CD19 cells/100 cells in Blood
8
8
10.11
4.53
2.1
2.1
%
9.0
4.3
—
8
8
(21494814) CD8 cells/100 lymphocytes in Specimen
8
8
10.11
4.53
2.1
2.1
—
—
—
0
0
(3013115) Eosinophils [#/volume] in Blood
304
2500
1.42
4.49
9.4
7.6
e9/l
0.2
0.2
0.04
277
2195
(40763571) Iron/Transferrin [Ratio] in Serum or Plasma
72
431
1.76
4.48
3.8
2.5
%
25.3
24.2
0.19
66
389
(3013707) Erythrocyte sedimentation rate by Westergren method
358
3035
1.42
4.44
4.9
3.7
mm/h
8.4
7.4
0.97
334
2801
(3017181) Myelocytes/100 leukocytes in Blood
55
304
1.89
4.43
6.7
4.7
%
0.4
0.8
1.28
13
71
(3018010) Neutrophils/100 leukocytes in Blood
298
2447
1.42
4.42
8.4
6.8
%
52.9
53.6
0.48
287
2329
(3002582) Erythrocytes [#/volume] in Urine
168
1241
1.48
4.38
4.2
3.1
e6/l
18.1
119.3
1.07
126
921
(3042111) Morphology [Interpretation] in Bone marrow Narrative
10
22
4.60
4.31
1.5
2.3
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
159
1166
1.49
4.29
3.7
3.0
—
—
—
0
0
(3025159) Blasts/100 leukocytes in Blood
52
286
1.89
4.26
7.0
4.8
%
0.1
0.0
0.33
13
54
(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay
13
37
3.57
4.07
1.3
1.1
—
—
—
0
0
(3025547) Thyroglobulin Ab [Units/volume] in Serum or Plasma
14
42
3.39
4.06
3.5
3.1
u/ml
198.6
79.0
—
5
12
(3013826) Glucose [Moles/volume] in Serum or Plasma
272
2225
1.40
4.00
5.4
4.7
mmol/l
6.4
6.2
0.68
250
1971
(3018133) Calcium [Moles/volume] in Urine
15
48
3.18
3.95
2.9
3.6
mmol/l
2.3
2.4
0.03
15
48
(3000570) Elastase.pancreatic [Mass/mass] in Stool
21
82
2.62
3.92
1.4
1.3
ug/g
300.5
364.0
—
8
34
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
525
4837
1.55
3.83
12.3
9.0
mg/l
18.2
21.2
1.57
399
3439
(43055120) Cytomegalovirus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection
26
114
2.34
3.83
5.9
7.4
—
494.9
—
0
14
(3002179) Metamyelocytes/100 leukocytes in Blood
51
289
1.83
3.82
5.9
4.3
%
0.4
0.5
—
10
52
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
402
3534
1.39
3.70
9.0
6.4
ml/min/173m2
109.1
106.9
1.16
306
2537
(40767503) Oxygen content in Capillary blood by calculation
18
67
2.74
3.68
2.7
2.7
%
18.0
17.7
0.10
13
37
(3002032) Base excess in Venous blood by calculation
83
547
1.60
3.61
6.0
7.2
mmol/l
1.7
1.4
0.42
75
438
(3009508) Creatinine [Moles/volume] in Urine
143
1060
1.45
3.60
3.8
3.9
mmol/l
9.5
9.1
0.26
132
950
(3023520) Reticulocytes [#/volume] in Blood
45
252
1.85
3.52
4.4
4.5
e9/l
68.3
63.6
0.32
32
172
(3026389) Candida sp identified in Specimen by Organism specific culture
18
69
2.66
3.50
1.2
1.3
—
—
—
0
0
(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay
24
107
2.29
3.43
1.3
1.3
—
—
—
0
0
(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay
24
107
2.29
3.43
1.3
1.3
—
—
—
0
0
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
394
3474
1.37
3.42
3.1
2.4
mmol/l
5.5
5.4
0.31
373
3196
(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma
176
1370
1.40
3.36
3.8
3.2
u/l
32.9
29.7
0.56
171
1296
(3021440) Promyelocytes/100 leukocytes in Blood
50
294
1.76
3.35
7.3
4.7
%
0.1
0.1
0.04
12
64
(3013742) Prealbumin [Mass/volume] in Serum or Plasma
57
348
1.70
3.34
3.7
3.7
g/l
0.2
0.2
0.15
57
332
(3039000) Anion gap in Blood
11
32
3.48
3.34
5.2
19.1
mmol/l
12.6
11.4
0.43
11
25
(3022948) Iron [Moles/volume] in Serum or Plasma
80
533
1.58
3.33
3.6
2.4
umol/l
15.3
15.0
0.10
74
496
(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma
62
389
1.66
3.29
3.4
4.6
ng/l
282.3
1051.2
1.17
46
301
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
55
335
1.70
3.26
1.9
1.6
—
—
—
0
0
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
332
2865
1.34
3.25
4.1
3.1
mmol/mol
37.2
36.6
0.44
315
2694
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
149
1133
1.41
3.24
1.7
1.5
pmol/l
90.2
97.3
1.26
77
626
(3004789) Transferrin [Mass/volume] in Serum or Plasma
74
488
1.59
3.22
3.7
2.4
g/l
2.5
2.6
0.14
68
443
(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma
10
28
3.61
3.20
1.3
1.3
nmol/l
—
—
—
0
0
(3018572) Chloride [Moles/volume] in Blood
11
33
3.38
3.20
5.2
18.5
mmol/l
105.5
105.4
0.05
11
26
(3010503) CD19 cells [#/volume] in Blood
8
15
5.39
3.20
2.1
2.4
e9/l
0.1
0.1
—
8
15
(3045209) Lutropin/Follitropin [Ratio] in Serum or Plasma
7
11
6.42
3.19
1.1
1.0
—
—
—
0
0
(3018095) Leukocytes [#/volume] in Urine
196
1565
1.37
3.18
5.1
3.5
e6/l
38.0
65.9
0.89
131
986
(3012516) Albumin [Mass/volume] in Urine
75
498
1.58
3.17
4.4
4.0
mg/l
59.3
103.7
1.16
67
376
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
55
339
1.68
3.13
1.9
1.7
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
151
1161
1.40
3.07
2.5
2.3
—
—
—
0
0
(3020682) Albumin/Creatinine [Ratio] in Urine
76
514
1.55
2.98
5.0
4.8
mg/mmol
7.9
14.7
1.20
69
392
(3001788) Aldosterone [Moles/volume] in Serum or Plasma
11
35
3.18
2.94
1.5
1.2
pmol/l
329.3
339.8
—
6
30
(3048689) Calprotectin [Mass/mass] in Stool
124
929
1.42
2.92
2.9
2.8
ug/g
129.0
113.1
0.20
96
728
(3021960) Folate [Moles/volume] in Serum or Plasma
89
626
1.49
2.91
1.6
1.3
nmol/l
19.1
18.0
0.34
78
547
(1616796) Gas panel - Central venous blood
20
89
2.29
2.89
4.2
4.2
—
—
—
0
0
(3001820) Epstein Barr virus nuclear Ab [Presence] in Serum
6
9
6.72
2.87
1.0
1.3
—
—
—
0
0
(21494434) Karyotype in Bone marrow
8
18
4.49
2.80
1.4
1.4
—
—
—
0
0
(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma
63
415
1.58
2.78
2.2
2.1
mmol/l
2.4
2.4
1.57
54
342
(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain
33
182
1.86
2.75
1.5
1.6
—
—
—
0
0
(3003396) Base excess in Arterial blood by calculation
37
212
1.79
2.73
8.7
11.7
mmol/l
-0.1
0.3
0.17
26
168
(3008757) Leukocyte morphology finding [Identifier] in Blood
12
43
2.83
2.66
2.1
5.3
—
—
—
0
0
(3027238) Thyroperoxidase Ab [Units/volume] in Serum or Plasma
70
480
1.52
2.59
1.3
1.2
iu/ml
123.6
142.7
0.17
23
174
(40761511) CBC panel - Blood by Automated count
533
5018
1.44
2.58
11.1
7.4
—
—
—
0
0
(3017143) Hepatitis C virus Ab [Presence] in Serum
131
1012
1.37
2.57
1.8
1.6
—
—
—
0
0
(3012501) Base excess in Blood by calculation
18
81
2.26
2.56
4.2
3.9
mmol/l
1.4
2.0
0.66
13
39
(3013290) Carbon dioxide [Partial pressure] in Blood
18
81
2.26
2.56
4.2
3.9
kpa
5.3
4.8
2.42
18
81
(3027315) Oxygen [Partial pressure] in Blood
18
81
2.26
2.56
4.2
3.3
kpa
9.8
9.5
0.40
18
81
(3005719) IgG [Mass/volume] in Serum or Plasma
60
399
1.56
2.55
4.4
2.9
g/l
10.9
10.2
0.91
54
368
(3042936) Bacteria identified in Isolate by Culture
67
459
1.52
2.50
2.1
2.0
—
—
—
0
0
(3026493) Urate [Moles/volume] in Serum or Plasma
81
578
1.46
2.48
3.6
3.4
umol/l
316.6
2731.1
1.34
76
529
(3016407) Fibrinogen [Mass/volume] in Platelet poor plasma by Coagulation assay
35
204
1.76
2.46
3.6
6.8
g/l
4.0
3.1
1.81
35
197
(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma
136
1065
1.35
2.44
2.5
2.4
u/l
54.9
54.3
0.08
127
980
(3000991) Gas panel - Venous blood
70
488
1.49
2.41
9.4
9.6
—
—
—
0
0
(3036535) Thyroglobulin [Mass/volume] in Serum or Plasma
6
12
5.04
2.40
5.8
7.8
—
—
—
0
0
(1001509) Gas and Carbon monoxide and Electrolytes panel - Arterial blood
6
12
5.04
2.40
1.0
1.5
—
—
—
0
0
(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma
9
27
3.37
2.40
1.2
1.3
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
36
214
1.72
2.38
2.2
1.6
—
—
—
0
0
(3029080) Hemoglobin [Entitic mass] in Reticulocytes
8
22
3.67
2.37
2.1
1.5
pg
36.3
32.1
—
8
22
(3027831) CD3-CD16+CD56+ (Natural killer) cells/100 cells in Blood
15
65
2.34
2.33
2.3
2.7
%
12.7
9.3
—
7
57
(4306422)
15
65
2.34
2.33
1.4
1.2
—
—
—
0
0
(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma
140
1110
1.34
2.31
2.4
2.5
mg/l
2.8
2.6
0.70
114
959
(1175553) Vedolizumab and Vedolizumab Ab panel [Mass/volume] - Serum or Plasma
6
13
4.65
2.27
6.0
11.4
—
—
—
0
0
(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma
67
469
1.48
2.27
4.3
4.6
umol/l
5.1
7.2
0.87
59
374
(3009542) Hematocrit [Volume Fraction] of Blood
529
4999
1.39
2.27
13.6
10.1
%
39.6
40.6
2.79
446
4258
(3036489) Thrombin time
36
218
1.69
2.24
3.5
5.9
s
21.1
22.0
0.93
31
202
(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma
68
480
1.47
2.21
1.3
1.5
pmol/l
452.5
32692737.0
0.80
60
416
(46235128) Lupus anticoagulant aPTT and dRVVT screening panel W Reflex
8
24
3.36
2.18
1.5
1.1
—
—
—
0
0
(3009340) Metanephrine [Moles/volume] in Serum or Plasma
8
24
3.36
2.18
1.1
1.2
nmol/l
—
—
—
0
0
(3003101) Alpha 1 antitrypsin [Mass/mass] in Stool
6
14
4.32
2.15
3.0
3.1
ug/g
184.3
176.5
—
6
14
(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma
6
14
4.32
2.15
4.5
7.5
ug/l
14.1
24.1
—
6
14
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
69
494
1.45
2.09
2.0
1.8
—
—
—
0
0
(21493690) Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood
14
62
2.29
2.09
2.6
2.7
—
—
—
0
0
(3012565) Volume of 24 hour Urine
5
10
5.03
2.07
1.4
1.1
ml
2506.0
2912.5
—
5
10
(3039429) Cortisol [Moles/volume] in Saliva (oral fluid)
7
20
3.53
2.06
2.1
1.6
nmol/l
24.5
1.2
—
7
15
(3002173) Hemoglobin [Mass/volume] in Arterial blood
29
171
1.73
2.00
9.7
11.1
g/l
123.5
126.6
0.31
29
161
(3030905) Polymorphonuclear cells [#/volume] in Blood
20
105
1.93
1.97
5.0
3.7
e9/l
3.5
3.6
0.12
20
105
(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma
69
500
1.43
1.97
2.7
1.9
—
—
—
0
0
(3010421) pH of Blood
18
91
2.01
1.97
4.2
3.6
ph
7.4
7.4
0.21
18
81
(3007853) Bacteria identified in Skin by Aerobe culture
70
509
1.42
1.97
2.0
1.5
—
—
—
0
0
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
21
113
1.89
1.94
13.0
15.8
—
—
—
0
0
(3013327) Hepatitis A virus IgM Ab [Presence] in Serum
18
92
1.99
1.92
1.3
1.1
—
—
—
0
0
(3031040) Bacteria [#/volume] in Urine by Automated count
326
2928
1.24
1.91
5.4
3.7
e6/l
17.0
403.1
—
5
23
(3019473) Protein [Mass/volume] in Cerebral spinal fluid
22
121
1.85
1.90
1.2
3.0
mg/l
490.1
447.0
0.13
22
113
(3012110) Lysozyme [Mass/volume] in Serum or Plasma
14
65
2.18
1.89
1.1
2.0
mg/l
8.5
8.4
0.03
14
60
(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells
14
65
2.18
1.89
1.5
2.5
—
—
—
0
0
(3049714) Procollagen type I.N-terminal propeptide [Mass/volume] in Serum
7
22
3.21
1.88
3.3
4.8
ug/l
162.7
157.7
—
7
22
(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma
25
144
1.77
1.88
6.3
2.7
ng/l
201.5
119.9
0.37
20
126
(3044355) Beta 2 glycoprotein 1 IgG Ab [Units/volume] in Serum or Plasma by Immunoassay
17
86
2.00
1.86
1.5
1.2
u/ml
1.8
4.7
—
8
44
(44816844) Macroprolactin [Units/volume] in Serum or Plasma
21
115
1.86
1.85
1.4
1.5
—
—
—
0
0
(3032035) Polymorphonuclear cells/100 leukocytes in Blood
20
108
1.88
1.83
5.1
3.9
%
51.8
53.6
0.22
20
108
(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)
32
200
1.63
1.81
3.7
2.4
ml/min/173m2
88.7
93.9
0.25
12
66
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
87
667
1.35
1.80
2.8
2.7
e6/l
0.6
1.0
1.21
39
358
(3025941) Bacteria identified in Stool by Culture
43
289
1.52
1.80
1.4
1.2
—
—
—
0
0
(3021879) Hepatitis B virus core Ab [Presence] in Serum
82
623
1.36
1.80
1.6
1.5
—
—
—
0
0
(3003338) MCHC [Mass/volume]
497
4696
1.29
1.79
14.3
11.2
g/l
333.7
334.7
1.36
492
4639
(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection
10
41
2.46
1.76
3.6
1.5
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
54
384
1.44
1.73
1.6
1.9
—
—
—
0
0
(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma
101
797
1.32
1.73
1.5
1.6
%
1.4
1.4
0.64
91
735
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
85
654
1.35
1.72
3.0
2.8
e6/l
7.0
4.1
0.30
38
345
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
32
203
1.61
1.72
1.3
1.3
—
—
—
0
0
(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection
8
32
2.52
1.60
4.3
1.6
—
—
—
0
0
(3011391) Calcitriol [Moles/volume] in Serum or Plasma
8
32
2.52
1.60
1.1
1.2
—
—
—
0
0
(43055514) Macroprolactin [Presence] in Serum or Plasma
7
26
2.71
1.58
1.1
1.2
—
—
—
0
0
(3001467) Alkaline phosphatase.bone [Enzymatic activity/volume] in Serum or Plasma
7
26
2.71
1.58
1.0
1.0
u/l
206.6
118.3
—
7
17
(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma
31
200
1.58
1.57
1.9
1.7
—
—
—
0
0
(21494815) CD4 cells/100 lymphocytes in Specimen
13
64
2.05
1.55
2.4
2.7
—
41.8
—
0
5
(3008152) Bicarbonate [Moles/volume] in Arterial blood
18
100
1.82
1.54
3.9
11.9
mmol/l
25.0
23.5
0.76
18
90
(3051651) Icteric interference index of Serum or Plasma
8
33
2.44
1.54
3.9
4.7
—
—
—
0
0
(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection
5
15
3.35
1.52
4.4
1.7
—
—
—
0
0
(3004119) Hemoglobin [Mass/volume] in Venous blood
27
171
1.61
1.48
4.5
4.9
g/l
133.4
133.5
0.01
27
165
(3019060) Gas panel - Arterial blood
18
102
1.79
1.46
3.7
9.1
—
—
—
0
0
(3002222) Hepatitis E virus IgM Ab [Presence] in Serum
9
38
2.39
1.46
1.3
1.0
—
—
—
0
0
(3003181) Sodium [Moles/volume] in Urine
9
38
2.39
1.46
8.4
1.8
mmol/l
98.7
75.4
—
9
33
(3006922) Hepatitis E virus Ab [Presence] in Serum
9
39
2.33
1.43
1.3
1.1
—
—
—
0
0
(3006418) Campylobacter sp identified in Tissue by Organism specific culture
25
157
1.62
1.42
1.4
1.1
—
—
—
0
0
(3009041) Cardiolipin IgG Ab [Units/volume] in Serum by Immunoassay
15
81
1.87
1.41
1.4
1.2
u/ml
3.2
4.4
—
6
45
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
115
950
1.26
1.40
3.2
2.3
—
—
—
0
0
(3032185) JC virus DNA [#/volume] (viral load) in Serum or Plasma by NAA with probe detection
5
17
2.96
1.36
5.6
5.9
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
142
1206
1.23
1.35
3.2
2.3
—
—
—
0
0
(3008295) Osmolality of Serum or Plasma
10
47
2.15
1.34
4.5
2.0
mosm/kgh2o
297.9
296.6
—
10
41
(3000504) BK virus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection
6
24
2.51
1.30
11.3
7.9
—
—
—
0
0
(3022145) Colonoscopy Study observation
42
303
1.41
1.29
1.6
1.5
—
—
—
0
0
(3032390) JC virus DNA [#/volume] (viral load) in Urine by NAA with probe detection
5
18
2.79
1.28
4.2
6.3
—
—
—
0
0
(3003752) BK virus DNA [Units/volume] (viral load) in Urine by NAA with probe detection
5
18
2.79
1.28
4.2
6.5
—
—
—
0
0
(3016650) Hepatitis A virus Ab [Presence] in Serum
17
99
1.74
1.28
1.2
1.1
—
—
—
0
0
(3014111) Lactate [Moles/volume] in Serum or Plasma
41
295
1.42
1.28
8.8
8.6
mmol/l
1.6
1.3
0.91
34
279
(3014765) Yersinia sp identified in Stool by Organism specific culture
25
162
1.57
1.28
1.4
1.1
—
—
—
0
0
(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability
8
35
2.30
1.27
1.1
1.2
—
—
—
0
0
(3045142) Bone marrow Pathology biopsy report
6
25
2.41
1.24
1.5
1.8
—
—
—
0
0
(3001122) Ferritin [Mass/volume] in Serum or Plasma
282
2570
1.18
1.24
3.9
2.9
ug/l
61.5
56.2
0.29
258
2412
(3004588) Protein electrophoresis panel - Serum or Plasma
12
63
1.92
1.23
1.2
1.7
—
—
—
0
0
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
22
140
1.59
1.21
1.1
1.6
—
—
—
0
0
(42529406) Shigella sp [Presence] in Stool by Culture
25
165
1.54
1.19
1.4
1.2
—
—
—
0
0
(3029023) Hepatitis E virus IgG Ab [Presence] in Serum by Immunoassay
8
38
2.12
1.18
1.4
1.0
—
—
—
0
0
(4010399)
30
207
1.47
1.17
1.4
1.4
—
—
—
0
0
(3051611) Lipemic interference index of Serum or Plasma
8
39
2.06
1.15
4.0
4.3
—
—
—
0
0
(3016914) Bacteria identified in Cerebral spinal fluid by Culture
8
39
2.06
1.15
1.8
1.6
—
—
—
0
0
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
66
523
1.29
1.14
3.2
2.9
ng/l
177.9
1133.6
1.87
29
239
(3020044) Glucose [Moles/volume] in Cerebral spinal fluid
18
111
1.64
1.13
1.3
3.0
mmol/l
3.9
3.5
0.74
18
104
(3005570) Glucose [Moles/volume] in Urine
7
30
2.35
1.12
1.6
1.7
—
—
—
0
0
(3044290) Cell count panel - Cerebral spinal fluid
17
104
1.65
1.10
1.4
3.2
—
—
—
0
0
(3037121) Protein [Mass/volume] in Urine
27
185
1.48
1.10
5.4
5.9
g/l
0.3
0.3
0.26
20
128
(42870365) C reactive protein [Mass/volume] in Blood by High sensitivity method
5
21
2.39
1.09
3.4
1.3
—
23.3
—
0
7
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
103
866
1.23
1.09
2.9
2.3
ng/l
47.2
44.3
0.03
46
323
(3024891) Influenza virus A+B Ag [Presence] in Specimen
30
211
1.44
1.08
1.2
1.1
—
—
—
0
0
(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture
38
280
1.38
1.06
1.6
1.4
—
—
—
0
0
(3010130) Cytomegalovirus IgG Ab [Units/volume] in Serum or Plasma
28
195
1.46
1.06
2.0
1.7
u/ml
90.2
104.0
—
5
22
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
36
264
1.39
1.04
3.7
2.3
—
—
—
0
0
(3004809) Band form neutrophils/100 leukocytes in Blood
9
47
1.93
1.02
2.8
3.7
%
0.9
1.9
—
9
35
(40768797) Stomach Pathology biopsy report
50
389
1.31
1.00
1.2
1.3
—
—
—
0
0
(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing
9
49
1.85
0.99
1.0
1.1
—
—
—
0
0
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
356
3343
1.15
0.98
3.0
2.4
mmol/l
1.2
1.1
1.19
339
3160
(3011363) Streptococcus pneumoniae Ag [Presence] in Urine
5
23
2.18
0.98
1.0
1.1
—
—
—
0
0
(3034770) Mitochondria Ab [Titer] in Serum
20
132
1.53
0.98
1.7
1.5
—
—
—
0
0
(3013512) EKG study
79
654
1.24
0.97
3.1
2.4
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
329
3074
1.15
0.97
5.3
3.8
—
—
—
0
0
(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay
37
278
1.35
0.94
1.8
1.5
—
—
—
0
0
(3052851) Hemolysis interference index of Serum or Plasma
16
101
1.60
0.94
3.7
3.3
—
—
—
0
0
(3044889) 12 lead EKG panel
233
2129
1.15
0.94
2.7
2.2
—
—
—
0
0
(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection
9
52
1.74
0.92
3.9
1.4
—
—
—
0
0
(4268621)
10
55
1.83
0.92
2.4
2.1
—
—
—
0
0
(3016038) Potassium [Moles/volume] in Urine
6
28
2.15
0.91
10.7
2.0
mmol/l
22.6
31.2
—
6
28
(3013005) Retinol [Moles/volume] in Serum or Plasma
10
56
1.80
0.88
3.1
2.9
umol/l
1.8
1.8
—
10
56
(3008898) HLA-B27 [Presence]
21
298
0.69
0.87
1.0
1.1
—
—
—
0
0
(40768446) Kidney Pathology biopsy report
6
30
2.01
0.87
1.5
1.9
—
—
—
0
0
(3007080) Epstein Barr virus nuclear IgG Ab [Units/volume] in Serum
36
274
1.33
0.86
1.8
1.5
u/ml
180.2
187.7
0.10
22
145
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
15
96
1.58
0.85
3.1
1.7
—
—
—
0
0
(40758897) Direct antiglobulin test.IgG specific reagent [Presence] on Red Blood Cells
6
31
1.94
0.84
1.3
3.5
—
—
—
0
0
(40758895) Direct antiglobulin test.complement C3d specific reagent [Presence] on Red Blood Cells
6
31
1.94
0.84
1.3
3.5
—
—
—
0
0
(3016701) Glucose [Moles/volume] in Serum or Plasma --2 hours post dose glucose
12
73
1.66
0.82
1.5
1.7
mmol/l
5.2
6.8
—
6
45
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
8
47
1.71
0.81
2.6
2.1
—
—
—
0
0
(3000081) cloZAPine [Moles/volume] in Serum or Plasma
8
47
1.71
0.81
9.8
25.4
nmol/l
2120.5
1369.6
—
8
47
(3045424) Erythrocytes [Presence] in Urine
10
58
1.74
0.80
2.4
1.2
—
—
—
0
0
(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid
29
217
1.35
0.78
1.3
1.2
—
—
—
0
0
(40768443) Skin Pathology biopsy report
17
115
1.49
0.77
1.1
1.1
—
—
—
0
0
(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection
6
34
1.77
0.76
3.8
1.5
—
—
—
0
0
(4094501)
7
38
1.85
0.73
1.0
1.1
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
209
1925
1.13
0.73
4.4
4.1
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
142
1275
1.15
0.73
3.6
2.5
—
—
—
0
0
(3019601) Blood group antibody investigation [Interpretation] in Plasma or RBC
10
60
1.68
0.72
1.1
2.1
—
—
—
0
0
(3005082) Progesterone [Moles/volume] in Serum or Plasma
10
60
1.68
0.72
1.9
1.3
nmol/l
57.9
36.2
—
10
55
(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection
9
57
1.59
0.71
3.0
1.8
—
—
—
0
0
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
95
829
1.17
0.71
2.5
2.9
mg/l
1.0
1.0
0.11
63
539
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
374
3568
1.12
0.71
3.3
2.6
mmol/l
2.7
2.7
0.08
354
3341
(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection
5
26
1.93
0.70
4.6
1.5
—
—
—
0
0
(3007847) Interleukin 2 Receptor Soluble [Units/volume] in Serum or Plasma
5
26
1.93
0.70
2.4
2.9
u/ml
600.4
800.3
—
5
26
(3048929) Epstein Barr virus Ab [Presence] in Serum
66
558
1.20
0.70
1.6
1.5
—
—
—
0
0
(3023410) Appearance of Cerebral spinal fluid
9
58
1.56
0.70
1.7
4.8
—
—
—
0
0
(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma
31
396
0.77
0.69
1.6
1.5
—
—
—
0
0
(4035726)
25
187
1.35
0.69
1.6
1.6
—
—
—
0
0
(3000093) Morphology [Interpretation] in Blood Narrative
7
42
1.67
0.68
1.0
1.0
—
—
—
0
0
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
41
503
0.80
0.67
1.4
1.3
—
—
—
0
0
(37020300) Entamoeba histolytica DNA [Presence] in Stool by NAA with probe detection
5
28
1.79
0.66
1.8
1.3
—
—
—
0
0
(3035285) Chloride [Moles/volume] in Venous blood
5
28
1.79
0.66
2.2
2.3
mmol/l
107.8
106.4
—
5
28
(3029536) Hepatitis C virus RNA [Units/volume] (viral load) in Specimen by NAA with probe detection
5
28
1.79
0.66
1.8
1.9
—
1224630.0
—
0
5
(3041354) Potassium [Moles/volume] in Venous blood
5
28
1.79
0.66
2.2
2.3
mmol/l
4.0
3.9
—
5
28
(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay
12
78
1.55
0.66
1.4
1.3
—
—
—
0
0
(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection
11
70
1.58
0.65
1.4
1.2
—
—
—
0
0
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
370
3537
1.11
0.65
3.2
2.6
mmol/l
1.4
1.4
0.36
350
3343
(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection
10
62
1.62
0.65
2.8
1.8
—
—
—
0
0
(3050238) Crystals [Presence] in Synovial fluid by Light microscopy
7
44
1.60
0.65
1.0
1.7
—
—
—
0
0
(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method
13
87
1.50
0.63
1.3
1.0
—
—
—
0
0
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
373
3571
1.11
0.63
3.3
2.6
mmol/l
4.5
4.5
0.03
353
3382
(3025839) Triglyceride [Moles/volume] in Serum or Plasma
91
800
1.16
0.63
1.7
1.6
mmol/l
1.4
1.3
0.88
83
720
(40760892) CBC W Ordered Manual Differential panel - Blood
128
1156
1.14
0.61
5.9
4.4
—
—
—
0
0
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
14
97
1.45
0.59
3.0
1.6
—
—
—
0
0
(3019309) Folate [Moles/volume] in Red Blood Cells
45
374
1.22
0.58
1.6
1.6
nmol/l
1061.3
1094.9
0.10
40
288
(21494755) Public health laboratory ask at order entry panel
56
655
0.84
0.58
1.3
1.2
—
—
—
0
0
(44817194) Complement alternate pathway AH50 actual/normal in Serum by Immunoassay
6
36
1.67
0.57
1.0
1.1
%
83.2
89.3
—
6
36
(3018993) Complement total hemolytic CH100 [Units/volume] in Serum or Plasma
6
36
1.67
0.57
1.0
1.1
—
—
—
0
0
(3015736) pH of Urine
189
1760
1.11
0.54
3.8
2.9
—
—
—
0
0
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
63
546
1.17
0.53
1.1
1.1
—
—
—
0
0
(4198724)
13
91
1.44
0.53
2.2
1.9
—
—
—
0
0
(3009261) Glucose [Presence] in Urine by Test strip
234
2205
1.10
0.52
4.1
3.1
estimate
0.0
0.0
0.00
56
463
(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay
9
132
0.68
0.52
1.1
1.1
—
—
—
0
0
(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture
37
444
0.82
0.51
1.5
1.6
—
—
—
0
0
(3011648) Oxygen content in Venous blood
6
40
1.50
0.51
7.2
9.8
%
14.0
12.1
—
6
40
(3022756) Ceruloplasmin [Mass/volume] in Serum or Plasma
6
40
1.50
0.51
1.0
1.1
mg/l
257.0
304.0
—
6
35
(3016417) Amylase.pancreatic [Enzymatic activity/volume] in Serum or Plasma
46
390
1.19
0.50
3.2
2.3
u/l
29.5
157.1
0.51
39
326
(44816559) Phosphatidylethanol [Mass/volume] in Blood
21
162
1.31
0.50
1.0
1.2
—
—
—
0
0
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
192
2049
0.91
0.50
2.8
2.5
—
—
—
0
0
(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence
10
67
1.50
0.50
2.2
1.9
—
—
—
0
0
(3002256) Pathology report gross observation
43
363
1.20
0.50
1.2
1.1
—
—
—
0
0
(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay
16
119
1.35
0.48
4.1
1.9
—
—
—
0
0
(4027681)
7
46
1.53
0.48
1.1
1.3
—
—
—
0
0
(3010156) C reactive protein [Mass/volume] in Serum or Plasma by High sensitivity method
18
233
0.77
0.48
1.3
1.5
mg/l
3.9
3.7
0.05
11
143
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
15
111
1.36
0.47
2.5
2.0
—
—
—
0
0
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
13
94
1.39
0.46
1.5
1.5
—
—
—
0
0
(3015024) Glucose [Moles/volume] in Serum or Plasma --1 hour post dose glucose
17
129
1.33
0.46
1.5
1.7
mmol/l
7.3
7.1
0.11
11
72
(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum
5
82
0.61
0.46
1.0
1.1
—
—
—
0
0
(3028369) Herpes simplex virus 1+2 DNA [Presence] in Specimen by NAA with probe detection
11
77
1.44
0.45
1.0
1.4
—
—
—
0
0
(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma
14
103
1.37
0.45
1.9
1.5
ug/l
0.3
0.5
—
7
35
(3050129) First trimester maternal screen panel - Serum or Plasma
49
564
0.86
0.44
1.4
1.4
—
—
—
0
0
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
179
1905
0.92
0.44
2.5
2.4
—
—
—
0
0
(3047007) Chlamydophila sp Ab [Presence] in Serum
9
128
0.70
0.43
1.0
1.2
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
102
932
1.11
0.42
1.5
1.5
—
—
—
0
0
(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma
81
896
0.89
0.42
1.5
1.5
—
—
—
0
0
(40760109) Toxoplasma gondii IgG Ab avidity [Ratio] in Serum by Immunoassay
5
32
1.57
0.42
1.2
1.2
—
—
—
0
0
(3018921) Toxoplasma gondii IgA Ab [Units/volume] in Serum
5
32
1.57
0.42
1.2
1.2
—
—
—
0
0
(3029937) Albumin [Presence] in Urine by Test strip
126
1165
1.10
0.42
4.5
3.1
estimate
0.0
0.0
0.80
56
462
(3017732) Neutrophils [#/volume] in Blood
33
277
1.20
0.42
3.7
2.0
e9/l
4.5
4.1
0.43
27
250
(42868647) JC virus Ab [Presence] in Serum or Plasma by Immunoassay
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
(3014064) Pregnancy associated plasma protein A [Multiple of the median] in Serum or Plasma
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
(3035350) Ketones [Presence] in Urine by Test strip
230
2187
1.08
0.41
4.2
3.0
estimate
0.0
0.0
0.00
55
452
(44790049)
8
59
1.36
0.41
2.3
1.7
—
—
—
0
0
(44790048)
8
59
1.36
0.41
2.3
1.7
—
—
—
0
0
(44790047)
8
59
1.36
0.41
2.3
1.7
—
—
—
0
0
(44806118)
8
59
1.36
0.41
2.3
1.7
—
—
—
0
0
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
31
368
0.83
0.41
1.2
1.2
—
—
—
0
0
(3025245) SCL-70 extractable nuclear Ab [Units/volume] in Serum by Immunoassay
11
79
1.40
0.41
1.3
1.3
—
1.4
—
0
8
(3002619) Bacteria identified in Specimen by Culture
0
18
0.00
0.40
0.0
1.0
—
—
—
0
0
(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay
20
248
0.80
0.40
1.4
1.4
—
—
—
0
0
(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum
7
104
0.67
0.39
2.4
2.5
—
—
—
0
0
(3003327) Ova and parasites identified in Stool by Light microscopy
31
261
1.20
0.39
2.3
1.7
—
—
—
0
0
(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma
309
2980
1.07
0.37
3.9
3.1
u/l
33.3
28.4
0.89
297
2856
(3011288) Drugs identified in Urine by Screen method
60
536
1.13
0.37
1.9
3.0
—
—
—
0
0
(3000492) Spirometry study
50
441
1.15
0.37
1.5
1.3
—
—
—
0
0
(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
10
72
1.40
0.37
2.8
1.8
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
183
1732
1.08
0.37
2.0
1.8
—
—
—
0
0
(3019897) Erythrocyte distribution width [Ratio] by Automated count
9
71
1.27
0.36
7.8
1.4
%
13.3
12.8
—
9
71
(3021601) Nitrite [Presence] in Urine by Test strip
229
2188
1.07
0.36
5.8
4.2
estimate
0.0
0.0
0.00
56
476
(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection
6
42
1.43
0.35
1.7
1.2
—
—
—
0
0
(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection
6
43
1.40
0.35
1.7
1.2
—
—
—
0
0
(3022621) pH of Urine by Test strip
29
247
1.18
0.33
2.2
2.2
—
—
—
0
0
(4034850)
6
88
0.68
0.33
3.8
6.3
—
—
—
0
0
(40768793) Breast Pathology biopsy report
6
47
1.28
0.32
1.8
1.1
—
—
—
0
0
(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot
7
52
1.35
0.31
1.3
1.2
—
—
—
0
0
(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid
7
52
1.35
0.31
1.3
1.1
—
—
—
0
0
(3053028) Streptococcus sp identified in Specimen by Organism specific culture
7
52
1.35
0.31
1.0
1.4
—
—
—
0
0
(3027529) Toxoplasma gondii IgM Ab [Units/volume] in Serum
7
96
0.73
0.31
1.1
1.3
—
—
—
0
0
(3035933) Granulocytes/100 leukocytes in Blood
7
53
1.32
0.31
1.0
1.2
—
—
—
0
0
(3034274) Bile acid [Moles/volume] in Serum --fasting
28
240
1.17
0.30
2.6
3.1
umol/l
3.9
6.4
1.48
19
190
(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid
7
54
1.30
0.30
1.3
1.1
—
—
—
0
0
(3019150) Specific gravity of Urine by Refractometry
109
1019
1.08
0.30
3.6
2.9
kg/l
1.0
1.0
1.48
21
138
(3028707) Methadone [Presence] in Urine by Screen method
41
363
1.14
0.30
1.7
2.8
—
—
—
0
0
(1761482) Bacteria [#/volume] in Urine by Culture
7
55
1.28
0.30
2.0
2.8
—
—
—
0
0
(4062490)
7
55
1.28
0.30
1.0
1.4
—
—
—
0
0
(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid
7
55
1.28
0.30
1.3
1.1
—
—
—
0
0
(3014007) Fractional oxyhemoglobin in Arterial blood
17
139
1.23
0.29
14.6
12.6
%
96.3
95.0
1.77
17
139
(3006217) Methemoglobin/Hemoglobin.total in Arterial blood
17
139
1.23
0.29
14.6
12.6
%
0.5
0.7
1.13
17
139
(40768804) Tissue Pathology biopsy report
133
1257
1.07
0.28
1.9
1.7
—
—
—
0
0
(3027944) Amphetamines [Presence] in Urine
72
780
0.91
0.28
1.5
2.0
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
50
452
1.12
0.27
3.5
3.3
—
—
—
0
0
(3013139) Helicobacter pylori Ag [Presence] in Stool
30
262
1.15
0.27
1.2
1.1
—
—
—
0
0
(3032836) C peptide [Moles/volume] in Serum or Plasma --fasting
15
122
1.24
0.27
1.9
2.5
nmol/l
0.8
0.6
0.72
15
99
(3037551) Cancer Ag 125 [Units/volume] in Serum or Plasma
17
141
1.21
0.26
1.4
1.8
u/ml
21.8
48.3
1.13
17
136
(3019497) Choriogonadotropin.beta subunit free [Moles/volume] in Serum or Plasma
5
71
0.70
0.26
1.0
2.0
—
—
—
0
0
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
10
127
0.78
0.25
2.4
2.1
—
—
—
0
0
(3020148) Glutamate decarboxylase 65 Ab [Units/volume] in Serum
14
114
1.23
0.25
1.3
1.1
iu/ml
173.0
225.0
—
5
46
(3028300) Cannabinoids [Presence] in Urine
74
794
0.92
0.24
1.6
2.1
—
—
—
0
0
(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma
32
284
1.13
0.24
4.0
2.4
%
30.8
32.9
0.54
24
205
(3016879) Cocaine [Presence] in Urine
69
741
0.92
0.23
1.5
2.1
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
168
1613
1.06
0.23
1.9
1.8
—
—
—
0
0
(3027008) Opiates [Presence] in Urine
74
792
0.93
0.23
1.6
2.1
—
—
—
0
0
(40768441) Liver Pathology biopsy report
5
39
1.28
0.23
1.6
1.7
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
234
2268
1.05
0.22
2.4
2.2
—
—
—
0
0
(3000208) Alpha tocopherol [Moles/volume] in Serum or Plasma
5
40
1.25
0.22
3.8
3.7
umol/l
21.4
25.3
—
5
40
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
499
5049
0.94
0.22
4.4
4.0
—
—
—
0
0
(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay
10
79
1.27
0.22
1.8
1.6
—
—
—
0
0
(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection
5
41
1.22
0.22
1.6
1.8
—
—
—
0
0
(37021073) Hepatitis C virus genotype in Serum or Plasma by Sequencing
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
(3009871) Measles virus Ab [Titer] in Serum
0
11
0.00
0.21
0.0
2.0
—
—
—
0
0
(4133840)
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
(21494890) Protein electrophoresis panel - 24 hour Urine
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(42869858) Acute and chronic leukemia fusion transcript panel - Blood or Tissue by Molecular genetics method
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
(3036782) Glucose [Moles/volume] in Pleural fluid
0
10
0.00
0.21
0.0
1.1
—
6.6
—
0
10
(3042517) Benzodiazepines panel - Urine
0
10
0.00
0.21
0.0
3.0
—
—
—
0
0
(3041082) Glomerular basement membrane Ab [Titer] in Serum by Immunofluorescence
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
(3004716) Salmonella sp identified in Stool by Organism specific culture
54
499
1.09
0.21
1.3
1.3
—
—
—
0
0
(3014051) Protein [Presence] in Urine by Test strip
8
105
0.76
0.21
2.1
1.9
—
—
—
0
0
(3014133) Dog dander IgE Ab [Units/volume] in Serum
17
198
0.85
0.21
1.1
1.1
u/ml
7.7
6.8
0.09
11
98
(3007463) Buprenorphine [Presence] in Urine
0
13
0.00
0.21
0.0
3.9
—
—
—
0
0
(4281824)
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
(3000764) Benzodiazepines [Presence] in Urine
74
787
0.93
0.20
1.6
2.1
—
—
—
0
0
(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot
6
51
1.18
0.19
1.3
1.2
—
—
—
0
0
(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot
6
51
1.18
0.19
1.3
1.2
—
—
—
0
0
(3020891) Body temperature
11
90
1.23
0.19
1.5
5.6
—
—
—
0
0
(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection
6
52
1.16
0.19
1.2
1.6
—
—
—
0
0
(40759836) Histone Ab [Presence] in Serum by Immunoblot
6
52
1.16
0.19
1.3
1.2
—
—
—
0
0
(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot
6
52
1.16
0.19
1.3
1.2
—
—
—
0
0
(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot
6
52
1.16
0.19
1.3
1.2
—
—
—
0
0
(3017044) Thyrotropin receptor Ab [Units/volume] in Serum
16
137
1.17
0.19
1.6
2.0
iu/l
3.4
5.4
—
5
56
(3045683) HLA typing for celiac disease panel - Blood or Tissue
6
53
1.13
0.18
1.0
1.0
—
—
—
0
0
(3045414) Leukocytes [Presence] in Urine
20
175
1.15
0.18
2.1
1.6
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
170
1643
1.05
0.18
4.1
2.9
—
—
—
0
0
(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay
22
248
0.88
0.18
1.2
1.2
—
—
—
0
0
(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection
114
1091
1.06
0.18
2.1
2.0
—
—
—
0
0
(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay
33
362
0.91
0.18
1.9
2.0
—
—
—
0
0
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
8
68
1.18
0.16
2.4
1.2
—
—
—
0
0
(3025018) Bordetella pertussis Ab [Titer] in Serum
8
69
1.16
0.16
1.3
1.1
—
—
—
0
0
(3009445) Proteinase 3 Ab [Units/volume] in Serum
18
158
1.14
0.16
1.5
1.3
—
9.5
—
0
7
(1002224) Polysomnography panel
16
139
1.16
0.16
1.1
1.1
—
—
—
0
0
(3023511) Choriogonadotropin [Units/volume] in Urine
35
380
0.92
0.16
1.5
1.2
—
—
—
0
0
(3001019) Free T4 and TSH panel - Serum or Plasma
24
266
0.90
0.16
1.8
1.5
—
—
—
0
0
(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method
15
130
1.16
0.15
1.1
2.0
—
—
—
0
0
(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection
16
140
1.15
0.15
1.5
1.6
—
—
—
0
0
(3024928) Oxygen saturation in Venous blood
9
83
1.09
0.14
7.1
6.3
—
—
—
0
0
(3038177) Helicobacter pylori Ab [Presence] in Serum
7
89
0.78
0.14
1.0
1.1
—
—
—
0
0
(3041806) Other cells [#/volume] in Blood by Manual count
9
106
0.85
0.13
1.7
1.6
—
—
—
0
0
(3017895) Helicobacter pylori Ab [Units/volume] in Serum
16
179
0.89
0.12
1.6
1.7
—
—
—
0
0
(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma
38
405
0.93
0.12
1.8
1.7
—
—
—
0
0
(3003888) Timothy IgE Ab [Units/volume] in Serum
31
288
1.08
0.12
1.1
1.1
u/ml
9.7
8.9
0.07
19
202
(3023351) European house dust mite IgE Ab [Units/volume] in Serum
30
322
0.93
0.11
1.1
1.2
u/ml
8.4
3.0
0.45
16
169
(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma
61
638
0.95
0.11
1.2
1.2
iu/ml
13.6
17.0
0.40
15
155
(3011397) Hemoglobin [Presence] in Urine by Test strip
106
1028
1.04
0.10
4.0
3.1
—
—
—
0
0
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
30
280
1.08
0.10
1.7
1.4
—
—
—
0
0
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
53
506
1.05
0.10
1.8
2.0
—
—
—
0
0
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
135
1317
1.03
0.10
1.6
1.6
—
—
—
0
0
(1175556) inFLIXimab Ab [Units/volume] in Serum by Immunoassay
5
44
1.14
0.10
1.6
4.3
—
39.3
—
0
6
(1001926) Buprenorphine [Presence] in Urine by Screen method
66
636
1.04
0.09
1.5
2.2
—
—
—
0
0
(3016018) Differential panel - Cerebral spinal fluid
6
55
1.09
0.09
1.7
3.0
—
—
—
0
0
(3023421) Hepatitis B virus surface Ab [Units/volume] in Serum
38
361
1.06
0.08
1.3
1.4
miu/ml
217.6
253.7
0.25
21
187
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
10
113
0.88
0.08
2.4
2.1
—
—
—
0
0
(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence
5
60
0.83
0.08
1.6
1.1
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
181
1841
0.98
0.08
1.7
1.8
—
—
—
0
0
(3042975) Streptococcus sp identified in Isolate by Organism specific culture
17
156
1.09
0.08
1.2
1.3
—
—
—
0
0
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
58
601
0.96
0.08
1.2
1.2
u/ml
18.1
7.6
0.26
16
214
(1761868) Lipid panel - Serum or Plasma
133
1357
0.97
0.07
2.1
1.8
—
—
—
0
0
(3047352) Trisomy 18 risk [Likelihood] in Fetus
35
333
1.05
0.07
1.6
1.5
—
—
—
0
0
(3005033) Fetal Nuchal fold Thickness US
35
333
1.05
0.07
1.6
1.5
—
—
—
0
0
(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain
20
186
1.08
0.07
1.2
1.3
—
—
—
0
0
(3025130) Human papilloma virus identified in Specimen
7
81
0.86
0.07
1.9
1.8
—
—
—
0
0
(40761535) Cells panel - Urine sediment
22
234
0.94
0.06
5.1
3.3
—
—
—
0
0
(3030981) Hyaline casts [#/volume] in Urine by Automated count
15
138
1.09
0.06
8.3
2.3
e6/l
0.2
0.2
0.18
15
130
(3023939) Sjogrens syndrome-A extractable nuclear Ab [Units/volume] in Serum
9
100
0.90
0.06
1.1
1.3
—
31.8
—
0
8
(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay
17
158
1.08
0.06
1.2
1.1
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
226
2238
1.02
0.05
2.2
1.9
—
—
—
0
0
(3017766) Complement C4 [Mass/volume] in Serum or Plasma
17
160
1.06
0.04
3.3
1.6
g/l
0.2
0.2
0.24
17
151
(3043238) Trisomy 21 risk [Likelihood] in Fetus
35
339
1.03
0.03
1.7
1.5
—
—
—
0
0
(3000620) Complement C3 [Mass/volume] in Serum or Plasma
17
161
1.06
0.03
3.3
1.6
g/l
1.1
1.2
0.44
17
151
(3002523) Influenza virus A Ag [Presence] in Specimen
14
148
0.94
0.02
1.1
1.1
—
—
—
0
0
(3003740) Influenza virus B Ag [Presence] in Specimen
14
148
0.94
0.02
1.1
1.1
—
—
—
0
0
(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma
46
469
0.98
0.02
1.6
1.5
—
—
—
0
0
(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum
21
204
1.03
0.00
1.2
1.3
—
—
—
0
0
(3037522) Nuclear Ab [Titer] in Serum
65
656
0.99
0.00
1.5
1.5
titre
283.6
540.6
1.00
11
97
(3000330) Specific gravity of Urine by Test strip
16
156
1.03
0.00
2.3
2.5
—
—
—
0
0
(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay
26
255
1.02
0.00
1.9
2.0
—
—
—
0
0
(3010726) Horse dander IgE Ab [Units/volume] in Serum
27
275
0.98
0.00
1.0
1.2
u/ml
13.7
3.9
—
6
79
(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum
29
285
1.02
0.00
1.3
1.2
—
46.1
—
0
11
(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age
42
425
0.99
0.00
1.5
1.4
—
—
—
0
0
(3023430) Cat dander IgE Ab [Units/volume] in Serum
18
177
1.02
0.00
1.1
1.1
u/ml
18.6
8.9
—
7
97
(3034603) RHD gene allele [Genotype] in Blood or Tissue by Molecular genetics method Nominal
10
102
0.98
0.00
1.7
1.5
—
—
—
0
0
(3015171) Extractable nuclear Ab [Units/volume] in Serum
15
148
1.01
0.00
1.3
1.2
—
1.6
—
0
6
(3014148) Varicella zoster virus Ab [Titer] in Serum
15
152
0.99
0.00
1.4
1.1
—
—
—
0
0
(3018171) Choriogonadotropin [Units/volume] in Serum or Plasma
67
666
1.01
0.00
3.0
2.4
u/l
6664.5
5789.1
0.11
28
251
(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection
130
1296
1.00
0.00
2.5
2.2
—
—
—
0
0
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
29
288
1.01
0.00
4.6
4.0
—
—
—
0
0
(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma
42
422
0.99
0.00
1.5
1.4
—
—
—
0
0
(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight
42
422
0.99
0.00
1.5
1.5
—
—
—
0
0
(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma
42
422
0.99
0.00
1.5
1.5
—
—
—
0
0
(3027450) Sjogrens syndrome-B extractable nuclear Ab [Units/volume] in Serum
11
111
0.99
0.00
1.3
1.3
—
35.1
—
0
7
(44813793)
6
63
0.95
0.00
1.0
1.1
—
—
—
0
0
(3019230) Fractional oxyhemoglobin in Venous blood
7
71
0.99
0.00
6.4
6.5
%
76.6
67.0
—
7
71
(3013784) Calcium.ionized [Moles/volume] in Serum or Plasma by Ion-selective membrane electrode (ISE)
0
7
0.00
0.00
0.0
1.9
—
—
—
0
0
(40761539) Cells [Type] in Urine sediment by Light microscopy
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(40763082) Lactate dehydrogenase [Enzymatic activity/volume] in Pleural fluid by Lactate to pyruvate reaction
0
8
0.00
0.00
0.0
1.3
—
491.1
—
0
8
(3007302) Hemoglobin [Mass/volume] in Mixed venous blood
0
8
0.00
0.00
0.0
2.3
—
—
—
0
0
(3018405) Lactate [Moles/volume] in Arterial blood
6
69
0.87
0.00
1.3
4.6
mmol/l
1.5
1.5
—
6
69
(3000936) Kiwifruit IgE Ab [Units/volume] in Serum
0
6
0.00
0.00
0.0
1.0
—
3.8
—
0
6
(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing
5
56
0.89
0.00
1.2
1.5
—
—
—
0
0
(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood
0
8
0.00
0.00
0.0
1.8
—
—
—
0
0
(3046279) Procalcitonin [Mass/volume] in Serum or Plasma
6
65
0.92
0.00
3.3
1.7
ug/l
0.5
1.0
—
6
55
(3009677) Dengue virus Ab [Presence] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3010937) Rubella virus Ab [Presence] in Serum
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(723473) SARS-CoV-2 (COVID-19) IgA Ab [Presence] in Serum or Plasma by Immunoassay
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3035320) C reactive protein [Mass/volume] in Body fluid
5
49
1.02
0.00
1.8
1.9
—
—
—
0
0
(40768806) Pleura Pathology biopsy report
0
6
0.00
0.00
0.0
2.3
—
—
—
0
0
(3024263) Appearance of Synovial fluid
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay
0
8
0.00
0.00
0.0
4.5
—
142.8
—
0
8
(3036428) Adenosine deaminase [Enzymatic activity/volume] in Pleural fluid
0
5
0.00
0.00
0.0
1.0
—
8.6
—
0
5
(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence
5
52
0.96
0.00
1.0
1.1
—
—
—
0
0
(3008536) Aspergillus sp Ab [Presence] in Serum
0
7
0.00
0.00
0.0
2.4
—
—
—
0
0
(3008401) Mugwort IgE Ab [Units/volume] in Serum
28
280
1.00
0.00
1.1
1.2
u/ml
2.9
1.4
0.59
18
169
(3013166) Neutrophils/100 leukocytes in Synovial fluid
0
5
0.00
0.00
0.0
1.6
—
43.6
—
0
5
(3019225) pH of Specimen
23
230
1.00
0.00
4.9
4.1
—
—
—
0
0
(3027974) Hepatitis B virus e Ag [Presence] in Serum
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3043409) Potassium [Moles/volume] in Arterial blood
5
57
0.88
0.00
1.0
5.2
mmol/l
3.9
3.8
—
5
52
(3019174) dRVVT (LA screen)
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3002670) Multiple inhalant allergen IgE Ab [Units/volume] in Serum
5
58
0.86
0.00
1.8
2.5
—
—
—
0
0
(40758310) Human epididymis protein 4 [Moles/volume] in Serum or Plasma
8
81
0.99
0.00
1.5
1.3
pmol/l
33.4
44.5
—
8
76
(3038864) risperiDONE [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.2
—
19.8
—
0
6
(40763480) Human metapneumovirus Ag [Presence] in Specimen
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3024869) Neuronal Ab [Presence] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3046426) Aquaporin 4 water channel IgG Ab [Presence] in Serum or Plasma
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(40757578) FLT3 gene targeted mutation analysis in Bone marrow by Molecular genetics method
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood
0
8
0.00
0.00
0.0
1.8
—
—
—
0
0
(40763791) Oxygen content in Venous blood by calculation
0
5
0.00
0.00
0.0
1.0
—
13.8
—
0
5
(3044009) aPTT.lupus sensitive (LA screen)
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3007625) Streptococcus pneumoniae Ag [Presence] in Specimen
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(40762365) Oxygen content in Arterial blood by calculation
0
5
0.00
0.00
0.0
3.0
—
17.0
—
0
5
(3017461) Flecainide [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
2.4
—
0.5
—
0
5
(3044927) Protein electrophoresis panel - Urine
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
(3017704) Immunofixation for Urine
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
(3012320) Pathologist interpretation of Cerebral spinal fluid tests
0
9
0.00
-0.00
0.0
1.6
—
—
—
0
0
(3012984) Norclozapine [Mass/volume] in Serum or Plasma
0
9
0.00
-0.00
0.0
14.2
—
—
—
0
0
(40765096) Chromosome analysis panel by Banding
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint E4_DISPUB and mortality.

Females

Parameter HR [95% CI] p-value
E4_DISPUB 2.342 [1.77, 3.1] < 0.001
Birth year 0.993 [0.98, 1.0] 0.105

During the follow-up period (1.1.1998 — 31.12.2019), 167 out of 5264 females with E4_DISPUB died.

Males

Parameter HR [95% CI] p-value
E4_DISPUB 2.384 [1.66, 3.42] < 0.001
Birth year 0.985 [0.98, 0.99] 0.002

During the follow-up period (1.1.1998 — 31.12.2019), 143 out of 6399 males with E4_DISPUB died.

Mortality risk

Mortality risk for people of age

years, who have E4_DISPUB.

N-year risk Females Males
1 0.252% 0.451%
5 1.399% 2.825%
10 3.368% 6.764%
15 6.23% 12.543%
20 10.628% 20.128%

Relationships between endpoints

Index endpoint: E4_DISPUB – Disorders of puberty

GWS hits: 2

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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