≡ Risteys
FG R12 + FR

Documentation Changelog GitHub Contact & Feedback

Delayed puberty

DOID EFO Endpoint Browser PheWeb

E4_DELPUB

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — E30.00, E30.09
  • Hospital discharge: ICD-9 — 2590
  • Cause of death: ICD-10 — E30.00, E30.09
  • Cause of death: ICD-9 — 2590

2 out of 7 registries used, show all original rules.

321

4. Check minimum number of events

None

321

5. Include endpoints

None

321

6. Filter based on genotype QC (FinnGen only)

321

Control definitions (FinnGen only)

Control exclude
E4_ENDOGLAND

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 7828 1705 6119
Only index persons 7752 1673 6079
Unadjusted period prevalence (%)
Whole population 0.14 0.05 0.17
Only index persons 0.20 0.06 0.23
Median age at first event (years)
Whole population 14.73 13.87 14.97
Only index persons 14.73 13.86 14.96

-FinnGen-

Key figures

All Female Male
Number of individuals 321 142 179
Unadjusted period prevalence (%) 0.07 0.05 0.08
Median age at first event (years) 14.62 14.15 14.99

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
293
Matched controls
2928
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
E30.09
ICD-10 Finland
Delayed puberty NOS
3254.5
179.6
155
*
E30.00
ICD-10 Finland
Familial delayed puberty
1485.8
169.8
149
*
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
41.3
73.5
92
32
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
65.9
68.6
78
16
E34.35
ICD-10 Finland
Abnormal growth retardation
470.7
42.3
41
*
101
Kela drug reimbursment
Anterior pituitary hypofunction
+∞
28.6
27
*
H01AC01
ATC
somatropin; parenteral
+∞
22.2
21
*
E30.9
ICD-10 Finland
Disorder of puberty, unspecified
+∞
20.0
19
*
2590A
ICD-9 Finland
Other endocrine disorders, Delay in sexual development and puberty, not elsewhere classified
+∞
20.0
19
*
E34.39
ICD-10 Finland
Short stature, not elsewhere classified
95.6
16.8
18
*
E23.04
ICD-10 Finland
Hypogonadotropic hypogonadism
48.8
12.0
14
*
121
Kela drug reimbursment
Severe hypofunction of sexual glands
24.1
11.7
16
7
E34.30
ICD-10 Finland
Short stature NOS
+∞
11.5
11
*
E23.01
ICD-10 Finland
Isolated deficiency of growth hormone
+∞
11.5
11
*
R62.8
ICD-10 Finland
Other lack of expected normal physiological development
16.8
10.5
16
10
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
5.5
10.2
30
60
N91.0
ICD-10 Finland
Primary amenorrhoea
17.5
10.0
15
9
E30.0
ICD-10 Finland
Delayed puberty
+∞
9.4
9
*
AA4CG
NOMESCO Finland
Extensive MRI examination of sella turcica with high intensity magnet
51.6
8.7
10
*
Z51.80
ICD-10 Finland
Manipulation of puberty development with hormone therapy
+∞
8.4
8
*
ZXD10
NOMESCO Finland
Scheduled procedure
2.3
8.2
97
528
E29.1
ICD-10 Finland
Testicular hypofunction
34.4
8.1
10
*
T10
ICPC
Growth delay
82.1
7.5
8
*
E28.3
ICD-10 Finland
Primary ovarian failure
+∞
7.3
7
*
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
10.4
7.1
13
13
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
5.3
6.9
20
40
G03FB08
ATC
dydrogesterone and estrogen; systemic (progestogens and estrogens, sequential prep.)
23.1
6.7
9
*
E30.8
ICD-10 Finland
Other disorders of puberty
71.3
6.5
7
*
301
Kela drug reimbursment
Growth hormone
+∞
6.3
6
*

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3023323) Follitropin [Units/volume] in Serum or Plasma
80
103
10.01
61.16
3.1
1.7
iu/l
8.0
8.1
0.01
67
82
(3009214) Lutropin [Units/volume] in Serum or Plasma
85
128
8.67
57.00
3.3
1.7
u/l
4.9
5.9
0.53
72
106
(3017446) Testosterone [Moles/volume] in Serum or Plasma
77
184
5.19
31.45
4.0
1.7
nmol/l
7.6
14.7
8.81
70
173
(3035637) Corticotropin [Mass/volume] in Plasma
18
27
7.00
11.59
1.8
1.6
—
—
—
0
0
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
234
1710
2.36
10.62
3.8
3.3
pmol/l
14.5
14.5
0.00
219
1536
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
136
826
2.12
9.57
1.5
1.5
u/ml
1.1
1.7
0.40
32
198
(40765089) Chromosome analysis panel - Blood by G-banded
16
28
5.96
8.89
1.0
1.0
—
—
—
0
0
(3007164) IgA [Mass/volume] in Serum or Plasma
118
726
1.99
7.66
1.6
1.5
g/l
1.8
2.0
0.75
61
452
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
120
754
1.94
7.25
8.4
7.5
mmol/l
1.2
1.2
0.31
98
657
(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma
126
808
1.92
7.15
3.2
2.6
nmol/l
63.9
67.0
0.82
116
753
(36660697) Celiac disease serology panel - Serum
59
286
2.30
7.06
1.2
1.2
—
—
—
0
0
(3015377) Calcium [Moles/volume] in Serum or Plasma
85
477
2.06
7.05
2.2
2.4
mmol/l
2.4
2.4
0.01
78
434
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
250
2013
2.09
7.03
4.5
3.8
mu/l
2.0
2.3
0.23
241
1878
(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma
12
20
6.19
6.95
2.8
7.4
—
—
—
0
0
(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma
109
686
1.89
6.42
8.7
7.5
mmol/l
1.2
1.2
0.01
100
637
(3022313) Gas panel - Capillary blood
32
129
2.64
5.65
7.4
5.1
—
—
—
0
0
(43055554) Base excess.100% oxygenated [Moles/volume] standard in Capillary blood by calculation
36
157
2.46
5.42
7.0
5.1
mmol/l
1.8
1.2
0.52
26
111
(3018418) pH of Serum or Plasma
70
416
1.87
4.77
4.0
3.2
ph
7.4
7.4
0.84
21
67
(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma
278
2439
2.04
4.65
8.8
7.0
u/l
28.3
28.7
0.07
270
2343
(3024561) Albumin [Mass/volume] in Serum or Plasma
94
633
1.69
4.14
5.3
5.5
g/l
37.9
38.7
0.79
88
598
(3022411) Androstenedione [Moles/volume] in Serum or Plasma
7
7
10.19
4.03
2.6
1.4
nmol/l
2.8
4.2
—
7
7
(3007461) Platelets [#/volume] in Blood
310
2881
3.22
3.93
16.0
12.3
e9/l
260.0
257.8
0.24
304
2792
(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma
177
1406
1.58
3.90
7.3
5.8
u/l
95.5
82.2
2.23
169
1314
(3026361) Erythrocytes [#/volume] in Blood
310
2887
3.15
3.79
16.2
12.3
e12/l
4.7
4.7
0.83
304
2797
(3019083) Insulin-like growth factor [Moles/volume] in Serum or Plasma
6
5
12.19
3.77
1.5
2.8
—
—
—
0
0
(3010813) Leukocytes [#/volume] in Blood
310
2890
3.12
3.72
16.3
12.3
e9/l
6.5
6.7
1.04
304
2798
(3023103) Potassium [Moles/volume] in Serum or Plasma
247
2140
1.67
3.65
11.7
8.3
mmol/l
3.9
3.9
0.68
236
2046
(3021901) Oxygen saturation in Capillary blood
10
26
3.94
3.55
5.1
3.5
—
—
—
0
0
(3027945) Reticulocytes/100 erythrocytes in Blood
31
156
2.09
3.38
3.8
7.2
%
1.8
1.4
0.42
31
146
(3005757) Coagulation factor V activity actual/normal in Platelet poor plasma by Coagulation assay
11
32
3.52
3.36
5.0
3.3
%
79.7
100.9
1.32
11
32
(3000850) Epithelial cells [#/volume] in Urine
59
375
1.70
3.16
3.7
2.5
e6/l
3.2
7.7
3.97
52
325
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
33
177
1.96
3.04
10.1
9.1
mmol/l
25.6
25.0
0.38
33
177
(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay
9
21
4.38
3.01
1.2
1.2
—
—
—
0
0
(3019550) Sodium [Moles/volume] in Serum or Plasma
244
2145
1.57
3.00
11.8
8.2
mmol/l
139.6
139.6
0.07
236
2059
(3012565) Volume of 24 hour Urine
5
5
10.13
2.99
1.4
1.0
ml
2506.0
3935.0
—
5
5
(3045209) Lutropin/Follitropin [Ratio] in Serum or Plasma
5
5
10.13
2.99
1.2
1.0
—
—
—
0
0
(3032773) Endomysium IgG Ab [Titer] in Serum
12
41
3.00
2.89
1.0
1.0
—
—
—
0
0
(3023368) Bacteria identified in Blood by Culture
55
352
1.68
2.87
4.7
4.0
—
—
—
0
0
(3030467) Casts [#/volume] in Urine by Automated count
74
511
1.58
2.86
2.9
3.0
e6/l
0.2
0.2
0.27
56
373
(3021960) Folate [Moles/volume] in Serum or Plasma
46
281
1.74
2.84
1.5
1.3
nmol/l
18.8
16.7
0.58
39
250
(3000570) Elastase.pancreatic [Mass/mass] in Stool
11
36
3.13
2.83
1.5
1.3
ug/g
286.5
403.6
—
5
14
(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma
7
14
5.08
2.74
1.3
1.3
—
—
—
0
0
(42870588) Differential panel, method unspecified - Blood
103
775
1.48
2.67
9.0
7.4
—
—
—
0
0
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
14
55
2.62
2.65
18.6
21.7
—
—
—
0
0
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
73
512
1.55
2.63
1.6
1.4
pmol/l
88.9
98.8
1.05
36
277
(3032080) INR in Blood by Coagulation assay
71
495
1.56
2.62
5.4
4.4
inr
1.0
1.1
0.78
30
181
(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma
7
15
4.74
2.61
1.3
1.3
nmol/l
—
—
—
0
0
(3021589) Normoblasts [#/volume] in Blood
137
1094
1.44
2.60
9.7
8.3
e9/l
0.0
0.0
0.42
111
878
(36304419) Bacteria [Presence] in Urine
74
522
1.54
2.60
3.0
2.9
—
—
—
0
0
(3018133) Calcium [Moles/volume] in Urine
9
25
3.67
2.59
3.3
2.6
mmol/l
2.5
2.6
—
9
25
(3049714) Procollagen type I.N-terminal propeptide [Mass/volume] in Serum
6
11
5.53
2.55
3.3
2.7
ug/l
133.0
112.7
—
6
11
(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma
31
174
1.87
2.53
4.3
5.8
ng/l
176.3
1399.7
0.67
24
121
(3027238) Thyroperoxidase Ab [Units/volume] in Serum or Plasma
36
214
1.77
2.45
1.2
1.3
iu/ml
169.9
141.8
0.15
13
77
(3027315) Oxygen [Partial pressure] in Blood
10
34
3.00
2.43
4.8
3.9
kpa
9.8
10.0
—
10
34
(3013290) Carbon dioxide [Partial pressure] in Blood
10
34
3.00
2.43
4.8
3.9
kpa
5.2
5.0
—
10
34
(3022096) Basophils/100 leukocytes in Blood
136
1095
1.42
2.43
9.5
7.4
%
0.6
0.6
0.14
131
1040
(3013707) Erythrocyte sedimentation rate by Westergren method
175
1473
1.41
2.42
4.5
3.5
mm/h
8.1
6.9
0.62
160
1364
(21494434) Karyotype in Bone marrow
5
8
6.33
2.38
1.4
1.0
—
—
—
0
0
(40761511) CBC panel - Blood by Automated count
278
2562
1.64
2.36
10.7
7.0
—
—
—
0
0
(40766189) Gliadin peptide IgG Ab [Units/volume] in Serum by Immunoassay
18
85
2.18
2.33
1.1
1.1
—
11.6
—
0
10
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
268
2454
1.56
2.28
11.8
8.8
mg/l
19.2
21.3
0.50
203
1703
(3009340) Metanephrine [Moles/volume] in Serum or Plasma
6
13
4.68
2.28
1.2
1.2
nmol/l
—
—
—
0
0
(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma
36
220
1.72
2.24
1.3
1.5
pmol/l
499.8
69035946.2
0.80
31
197
(3028369) Herpes simplex virus 1+2 DNA [Presence] in Specimen by NAA with probe detection
10
36
2.83
2.22
1.0
1.6
—
—
—
0
0
(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma
57
393
1.55
2.21
3.1
2.6
u/l
235.6
282.8
0.25
57
379
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
83
621
1.45
2.17
3.6
3.3
—
—
—
0
0
(3002582) Erythrocytes [#/volume] in Urine
77
569
1.46
2.15
3.8
3.0
e6/l
8.9
41.7
2.04
58
428
(40758558) Short blood count panel - Blood
76
561
1.46
2.13
6.0
7.2
—
—
—
0
0
(1616796) Gas panel - Central venous blood
10
37
2.76
2.12
5.3
5.0
—
—
—
0
0
(3006504) Eosinophils/100 leukocytes in Blood
138
1137
1.37
2.07
9.7
7.1
%
3.2
2.8
0.52
133
1072
(3030905) Polymorphonuclear cells [#/volume] in Blood
12
50
2.45
2.05
4.8
4.4
e9/l
4.0
3.5
0.31
12
50
(3032035) Polymorphonuclear cells/100 leukocytes in Blood
12
51
2.41
1.97
5.1
4.8
%
53.0
52.6
0.03
12
51
(3006315) Basophils [#/volume] in Blood
142
1186
1.35
1.92
9.0
7.1
e9/l
0.0
0.0
0.16
126
1035
(3001604) Monocytes [#/volume] in Blood
142
1186
1.35
1.92
9.1
7.0
e9/l
0.6
0.5
1.22
126
1035
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
20
107
1.93
1.91
1.9
1.6
—
—
—
0
0
(3012095) Magnesium [Moles/volume] in Serum or Plasma
38
248
1.60
1.87
5.7
7.1
mmol/l
0.8
0.8
0.45
38
237
(3017181) Myelocytes/100 leukocytes in Blood
26
153
1.76
1.86
6.0
5.2
%
0.5
0.8
—
6
43
(3010421) pH of Blood
10
40
2.55
1.85
4.8
3.5
ph
7.4
7.4
—
10
34
(3025941) Bacteria identified in Stool by Culture
24
139
1.79
1.81
1.5
1.1
—
—
—
0
0
(3013650) Neutrophils [#/volume] in Blood by Automated count
157
1340
1.34
1.81
10.3
8.8
e9/l
3.6
3.9
0.86
138
1161
(1175426) CD3 cells/100 lymphocytes in Blood
8
29
2.80
1.80
2.1
2.8
%
75.8
66.2
—
8
29
(3026389) Candida sp identified in Specimen by Organism specific culture
8
29
2.80
1.80
1.3
1.3
—
—
—
0
0
(3013115) Eosinophils [#/volume] in Blood
144
1218
1.33
1.75
9.5
7.5
e9/l
0.2
0.2
0.23
132
1078
(3025159) Blasts/100 leukocytes in Blood
24
141
1.76
1.74
6.5
5.4
%
0.2
0.0
—
6
32
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
211
1892
1.34
1.67
9.2
6.6
ml/min/173m2
110.3
107.9
1.00
157
1370
(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection
6
19
3.20
1.67
5.3
1.5
—
—
—
0
0
(3019069) Monocytes/100 leukocytes in Blood
136
1147
1.32
1.66
10.7
7.3
%
8.7
8.3
1.43
131
1092
(3009542) Hematocrit [Volume Fraction] of Blood
273
2554
1.46
1.64
12.6
9.5
%
40.3
41.5
2.22
225
2192
(37020300) Entamoeba histolytica DNA [Presence] in Stool by NAA with probe detection
5
14
3.61
1.62
1.8
1.1
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
30
192
1.62
1.61
1.9
2.1
—
—
—
0
0
(3019198) Lymphocytes [#/volume] in Blood
147
1259
1.31
1.59
9.0
6.9
e9/l
2.1
2.0
0.30
134
1125
(3008898) HLA-B27 [Presence]
7
159
0.43
1.59
1.0
1.1
—
—
—
0
0
(3000991) Gas panel - Venous blood
31
201
1.60
1.58
11.3
10.5
—
—
—
0
0
(3013742) Prealbumin [Mass/volume] in Serum or Plasma
27
170
1.64
1.55
3.5
3.3
g/l
0.2
0.2
0.52
27
158
(3042111) Morphology [Interpretation] in Bone marrow Narrative
5
15
3.37
1.53
2.0
2.1
—
—
—
0
0
(3051651) Icteric interference index of Serum or Plasma
5
15
3.37
1.53
5.4
5.5
—
—
—
0
0
(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection
5
15
3.37
1.53
6.2
1.6
—
—
—
0
0
(21493690) Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood
7
27
2.63
1.52
2.7
2.8
—
—
—
0
0
(3018095) Leukocytes [#/volume] in Urine
89
714
1.34
1.52
4.4
3.5
e6/l
26.8
49.3
0.79
62
452
(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay
9
37
2.47
1.49
1.2
1.2
—
—
—
0
0
(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay
9
37
2.47
1.49
1.2
1.2
—
—
—
0
0
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
170
1494
1.29
1.49
3.9
3.0
mmol/mol
37.3
36.8
0.25
161
1419
(3002179) Metamyelocytes/100 leukocytes in Blood
23
141
1.68
1.46
6.7
4.7
%
0.4
0.6
—
5
29
(3013327) Hepatitis A virus IgM Ab [Presence] in Serum
11
52
2.15
1.46
1.3
1.1
—
—
—
0
0
(4010399)
17
96
1.81
1.42
1.4
1.4
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
26
168
1.60
1.36
2.7
1.6
—
—
—
0
0
(3008757) Leukocyte morphology finding [Identifier] in Blood
5
17
2.97
1.36
2.0
7.2
—
—
—
0
0
(3051611) Lipemic interference index of Serum or Plasma
5
17
2.97
1.36
5.6
5.2
—
—
—
0
0
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
15
256
0.57
1.35
1.2
2.1
—
—
—
0
0
(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain
13
68
1.95
1.35
1.2
1.2
—
—
—
0
0
(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma
12
61
2.00
1.34
1.4
1.2
ug/l
0.3
0.3
—
6
17
(3002030) Lymphocytes/100 leukocytes in Blood
141
1222
1.27
1.34
9.8
6.9
%
32.3
31.7
0.26
136
1165
(3048689) Calprotectin [Mass/mass] in Stool
60
463
1.36
1.31
3.1
3.0
ug/g
139.7
134.6
0.03
49
357
(3013005) Retinol [Moles/volume] in Serum or Plasma
6
24
2.53
1.31
2.7
2.8
umol/l
1.5
1.7
—
6
24
(3003888) Timothy IgE Ab [Units/volume] in Serum
22
138
1.64
1.30
1.0
1.1
u/ml
9.1
11.3
0.21
13
101
(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid
5
18
2.80
1.29
1.4
1.1
—
—
—
0
0
(3018010) Neutrophils/100 leukocytes in Blood
138
1200
1.26
1.26
9.2
6.7
%
52.0
54.3
1.32
133
1149
(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection
5
19
2.66
1.22
1.8
1.1
—
—
—
0
0
(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid
5
19
2.66
1.22
1.4
1.1
—
—
—
0
0
(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma
63
496
1.34
1.21
2.1
2.3
mg/l
2.7
2.5
0.19
50
430
(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma
13
223
0.57
1.21
1.6
1.5
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
25
167
1.54
1.16
2.7
1.5
—
—
—
0
0
(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid
5
20
2.52
1.15
1.4
1.1
—
—
—
0
0
(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection
5
20
2.52
1.15
1.8
1.1
—
—
—
0
0
(3022145) Colonoscopy Study observation
25
168
1.53
1.13
1.5
1.5
—
—
—
0
0
(3043238) Trisomy 21 risk [Likelihood] in Fetus
9
165
0.53
1.11
1.8
1.5
—
—
—
0
0
(3003327) Ova and parasites identified in Stool by Light microscopy
19
120
1.62
1.11
1.8
1.7
—
—
—
0
0
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
196
1792
1.24
1.09
2.6
2.3
mmol/l
5.4
5.5
0.26
185
1636
(3023430) Cat dander IgE Ab [Units/volume] in Serum
14
82
1.74
1.07
1.1
1.1
u/ml
18.6
9.9
—
7
42
(3001122) Ferritin [Mass/volume] in Serum or Plasma
132
1160
1.23
1.06
3.0
2.9
ug/l
72.7
66.1
0.18
122
1095
(3044290) Cell count panel - Cerebral spinal fluid
9
46
1.98
1.04
1.1
3.0
—
—
—
0
0
(40768443) Skin Pathology biopsy report
11
60
1.86
1.04
1.1
1.1
—
—
—
0
0
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
5
22
2.29
1.03
2.8
1.7
—
—
—
0
0
(44816844) Macroprolactin [Units/volume] in Serum or Plasma
10
53
1.92
1.02
1.5
1.3
—
—
—
0
0
(3016502) Oxygen saturation in Arterial blood
16
99
1.65
1.02
17.1
15.5
%
97.0
96.9
0.03
16
94
(3005033) Fetal Nuchal fold Thickness US
9
161
0.55
1.01
1.7
1.4
—
—
—
0
0
(3047352) Trisomy 18 risk [Likelihood] in Fetus
9
161
0.55
1.01
1.7
1.4
—
—
—
0
0
(3015916) Alpha-1-Fetoprotein [Units/volume] in Serum or Plasma
7
35
2.02
1.00
3.0
3.8
u/ml
7.3
6.5
—
7
29
(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma
30
406
0.71
0.98
1.6
1.5
—
—
—
0
0
(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight
12
197
0.59
0.97
1.6
1.4
—
—
—
0
0
(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma
12
197
0.59
0.97
1.6
1.4
—
—
—
0
0
(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age
12
197
0.59
0.97
1.6
1.4
—
—
—
0
0
(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma
12
197
0.59
0.97
1.6
1.4
—
—
—
0
0
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
20
133
1.54
0.97
4.3
2.2
—
—
—
0
0
(3008401) Mugwort IgE Ab [Units/volume] in Serum
20
134
1.53
0.94
1.1
1.1
u/ml
4.0
1.3
0.75
12
82
(3009466) Valproate [Moles/volume] in Serum or Plasma
9
52
1.75
0.93
6.1
5.5
umol/l
368.7
398.4
—
9
46
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
6
28
2.16
0.92
1.2
1.1
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
34
255
1.37
0.91
1.9
1.5
—
—
—
0
0
(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma
66
545
1.27
0.91
2.7
2.5
u/l
57.7
54.4
0.30
61
506
(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells
6
29
2.09
0.89
1.5
3.0
—
—
—
0
0
(3023520) Reticulocytes [#/volume] in Blood
17
111
1.56
0.89
2.9
5.1
e9/l
66.7
64.0
0.10
11
80
(3025018) Bordetella pertussis Ab [Titer] in Serum
6
30
2.02
0.87
1.3
1.2
—
—
—
0
0
(3052851) Hemolysis interference index of Serum or Plasma
8
44
1.84
0.86
6.0
3.3
—
—
—
0
0
(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection
10
57
1.78
0.84
1.3
1.6
—
—
—
0
0
(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay
10
165
0.59
0.84
1.6
2.0
—
—
—
0
0
(3021440) Promyelocytes/100 leukocytes in Blood
21
147
1.46
0.82
7.1
5.3
%
0.0
0.1
—
5
39
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
38
296
1.32
0.81
2.1
2.7
e6/l
0.2
0.5
1.72
14
156
(3023351) European house dust mite IgE Ab [Units/volume] in Serum
22
156
1.44
0.81
1.1
1.2
u/ml
12.9
1.7
—
10
82
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
38
297
1.32
0.80
2.1
2.8
e6/l
3.6
3.0
0.12
16
157
(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)
15
98
1.56
0.80
2.3
2.4
ml/min/173m2
94.6
94.2
—
5
36
(3036071) Salmonella sp Ab [Titer] in Serum
0
24
0.00
0.79
0.0
1.2
—
—
—
0
0
(3004588) Protein electrophoresis panel - Serum or Plasma
6
33
1.83
0.79
1.3
2.1
—
—
—
0
0
(3041145) Herpes simplex virus IgM Ab [Presence] in Serum by Immunoassay
0
27
0.00
0.78
0.0
1.0
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
71
603
1.23
0.77
3.7
2.4
—
—
—
0
0
(3017143) Hepatitis C virus Ab [Presence] in Serum
64
538
1.24
0.76
1.7
1.6
—
—
—
0
0
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
14
91
1.56
0.76
1.6
1.4
—
26.3
—
0
9
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
31
237
1.34
0.76
1.1
1.0
—
—
—
0
0
(3009508) Creatinine [Moles/volume] in Urine
65
548
1.23
0.76
4.3
3.6
mmol/l
8.9
9.6
0.42
60
494
(3050129) First trimester maternal screen panel - Serum or Plasma
19
264
0.70
0.75
1.6
1.4
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
25
185
1.38
0.74
1.3
1.2
—
—
—
0
0
(40761535) Cells panel - Urine sediment
6
108
0.55
0.74
2.5
3.3
—
—
—
0
0
(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection
5
25
2.02
0.73
6.2
1.4
—
—
—
0
0
(4062490)
5
26
1.94
0.71
1.0
1.5
—
—
—
0
0
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
36
287
1.29
0.67
3.4
3.3
ng/l
183.2
1176.2
1.11
20
133
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
7
43
1.64
0.67
5.3
1.8
—
—
—
0
0
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
7
43
1.64
0.67
4.9
1.7
—
—
—
0
0
(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma
27
207
1.33
0.66
2.0
1.8
—
—
—
0
0
(3022621) pH of Urine by Test strip
15
103
1.48
0.66
2.1
2.1
—
—
—
0
0
(3027944) Amphetamines [Presence] in Urine
36
444
0.79
0.65
1.6
2.0
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
80
907
0.84
0.64
1.5
1.7
—
—
—
0
0
(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection
5
29
1.74
0.64
1.6
1.3
—
—
—
0
0
(3010726) Horse dander IgE Ab [Units/volume] in Serum
19
139
1.39
0.62
1.1
1.1
u/ml
13.7
4.1
—
6
34
(3046279) Procalcitonin [Mass/volume] in Serum or Plasma
5
30
1.68
0.61
3.8
1.8
ug/l
0.2
1.6
—
5
25
(3000492) Spirometry study
31
246
1.29
0.61
1.8
1.3
—
—
—
0
0
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
17
231
0.72
0.61
1.4
1.2
—
—
—
0
0
(3024522) Salmonella sp identified in Specimen by Organism specific culture
0
20
0.00
0.60
0.0
1.4
—
—
—
0
0
(3012568) Campylobacter sp identified in Specimen by Organism specific culture
0
20
0.00
0.60
0.0
1.4
—
—
—
0
0
(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection
0
20
0.00
0.60
0.0
1.4
—
—
—
0
0
(3050449) Albumin [Mass/time] in Urine collected for unspecified duration
0
21
0.00
0.60
0.0
2.6
—
89.4
—
0
16
(3014133) Dog dander IgE Ab [Units/volume] in Serum
14
97
1.46
0.60
1.1
1.1
u/ml
9.4
7.3
—
9
45
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
23
297
0.76
0.59
1.5
1.3
—
—
—
0
0
(3028679) Herpes simplex virus Ab [Presence] in Serum
0
22
0.00
0.59
0.0
1.1
—
—
—
0
0
(3013139) Helicobacter pylori Ag [Presence] in Stool
7
112
0.62
0.59
1.0
1.1
—
—
—
0
0
(3019897) Erythrocyte distribution width [Ratio] by Automated count
6
36
1.68
0.57
11.2
1.5
%
13.6
12.7
—
6
36
(3016879) Cocaine [Presence] in Urine
34
414
0.80
0.56
1.6
2.2
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
39
467
0.81
0.56
2.9
3.1
—
—
—
0
0
(3016650) Hepatitis A virus Ab [Presence] in Serum
9
60
1.51
0.55
1.2
1.1
—
—
—
0
0
(3006418) Campylobacter sp identified in Tissue by Organism specific culture
11
74
1.50
0.54
1.2
1.1
—
—
—
0
0
(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain
11
74
1.50
0.54
1.1
1.5
—
—
—
0
0
(3024891) Influenza virus A+B Ag [Presence] in Specimen
13
91
1.45
0.54
1.2
1.1
—
—
—
0
0
(43055120) Cytomegalovirus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection
9
62
1.46
0.53
5.7
6.6
—
868.4
—
0
7
(3042936) Bacteria identified in Isolate by Culture
29
233
1.27
0.53
1.9
2.1
—
—
—
0
0
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
10
66
1.53
0.53
1.2
1.7
—
—
—
0
0
(3013826) Glucose [Moles/volume] in Serum or Plasma
117
1072
1.14
0.53
6.3
5.1
mmol/l
6.9
6.2
0.70
102
950
(3028300) Cannabinoids [Presence] in Urine
38
453
0.82
0.52
1.7
2.1
—
—
—
0
0
(3014765) Yersinia sp identified in Stool by Organism specific culture
11
75
1.48
0.51
1.2
1.1
—
—
—
0
0
(3027008) Opiates [Presence] in Urine
38
451
0.82
0.50
1.7
2.1
—
—
—
0
0
(3042975) Streptococcus sp identified in Isolate by Organism specific culture
10
67
1.51
0.50
1.1
1.2
—
—
—
0
0
(3000764) Benzodiazepines [Presence] in Urine
38
449
0.83
0.49
1.7
2.2
—
—
—
0
0
(21494755) Public health laboratory ask at order entry panel
33
395
0.82
0.48
1.3
1.2
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
55
481
1.17
0.46
2.2
2.2
—
—
—
0
0
(42529406) Shigella sp [Presence] in Stool by Culture
11
77
1.44
0.46
1.2
1.2
—
—
—
0
0
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
7
50
1.41
0.45
1.4
1.5
—
—
—
0
0
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
93
1015
0.88
0.44
3.0
2.4
—
—
—
0
0
(3027475) Erythrocytes [#/volume] in Cerebral spinal fluid
7
51
1.38
0.44
1.4
2.8
e6/l
3807.4
59.2
—
7
42
(3016543) Leukocytes [#/volume] in Cerebral spinal fluid
7
51
1.38
0.44
1.4
2.8
e6/l
3.4
8.7
—
7
40
(3025271) CD3-CD16+CD56+ (Natural killer) cells [#/volume] in Blood
5
31
1.62
0.43
1.2
2.8
e9/l
0.2
0.2
—
5
21
(3019060) Gas panel - Arterial blood
8
57
1.41
0.42
6.3
12.8
—
—
—
0
0
(3001405) CD3+CD8+ (T8 suppressor) cells [#/volume] in Blood
5
32
1.57
0.42
1.2
2.8
e6/l
546.2
491.4
—
5
21
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
51
447
1.17
0.42
2.8
2.2
ng/l
62.9
15.7
0.46
24
156
(40768446) Kidney Pathology biopsy report
0
15
0.00
0.41
0.0
1.5
—
—
—
0
0
(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid
7
102
0.68
0.40
1.3
1.2
—
—
—
0
0
(3025468) Yersinia sp identified in Specimen by Organism specific culture
0
18
0.00
0.40
0.0
1.4
—
—
—
0
0
(3005988) Vibrio sp identified in Specimen by Organism specific culture
0
18
0.00
0.40
0.0
1.4
—
—
—
0
0
(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection
0
18
0.00
0.40
0.0
1.4
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
30
252
1.21
0.39
2.8
1.8
—
—
—
0
0
(4306422)
5
37
1.36
0.37
1.6
1.2
—
—
—
0
0
(3014007) Fractional oxyhemoglobin in Arterial blood
9
71
1.28
0.36
24.7
13.5
%
96.2
94.4
—
9
71
(44816559) Phosphatidylethanol [Mass/volume] in Blood
11
82
1.35
0.34
1.1
1.2
—
—
—
0
0
(3023511) Choriogonadotropin [Units/volume] in Urine
12
155
0.77
0.34
1.6
1.2
—
—
—
0
0
(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection
54
599
0.88
0.33
2.7
2.2
—
—
—
0
0
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
87
938
0.90
0.33
2.8
2.3
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
24
201
1.21
0.33
3.3
3.1
—
—
—
0
0
(40766183) Gliadin peptide IgA Ab [Units/volume] in Serum by Immunoassay
6
46
1.31
0.33
1.3
1.1
—
2.4
—
0
23
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
37
421
0.86
0.33
3.5
2.8
mg/l
1.0
1.0
0.02
24
274
(3004716) Salmonella sp identified in Stool by Organism specific culture
21
250
0.83
0.31
1.3
1.3
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
55
605
0.89
0.30
2.3
2.4
—
—
—
0
0
(3032836) C peptide [Moles/volume] in Serum or Plasma --fasting
7
55
1.28
0.30
1.7
3.1
nmol/l
0.8
0.7
—
7
43
(3013512) EKG study
36
317
1.15
0.30
2.9
2.2
—
—
—
0
0
(3019150) Specific gravity of Urine by Refractometry
46
510
0.89
0.29
3.7
2.9
kg/l
1.0
1.0
—
10
60
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
13
103
1.27
0.28
1.1
1.4
—
—
—
0
0
(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum
9
118
0.76
0.28
1.3
1.4
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
122
1160
1.08
0.26
2.4
2.2
—
—
—
0
0
(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma
50
455
1.12
0.26
1.5
1.7
%
1.5
1.4
0.40
45
422
(3034780) Angiotensin converting enzyme [Enzymatic activity/volume] in Serum or Plasma
5
75
0.66
0.26
1.0
2.0
u/l
36.0
37.5
—
5
70
(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture
15
123
1.23
0.26
1.7
1.4
—
—
—
0
0
(3006217) Methemoglobin/Hemoglobin.total in Arterial blood
9
73
1.24
0.25
24.7
13.1
%
0.5
0.7
—
9
73
(3030981) Hyaline casts [#/volume] in Urine by Automated count
9
77
1.17
0.24
8.8
2.6
e6/l
0.1
0.1
—
9
72
(3044889) 12 lead EKG panel
115
1095
1.08
0.24
2.5
2.2
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
44
400
1.12
0.24
1.5
1.5
—
—
—
0
0
(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma
13
106
1.24
0.23
1.8
1.5
—
—
—
0
0
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
14
168
0.83
0.23
1.6
1.4
—
—
—
0
0
(3021879) Hepatitis B virus core Ab [Presence] in Serum
38
343
1.12
0.23
1.6
1.6
—
—
—
0
0
(3037826) lamoTRIgine [Moles/volume] in Serum or Plasma
0
11
0.00
0.21
0.0
2.7
—
17.1
—
0
11
(4211845)
0
10
0.00
0.21
0.0
2.1
—
—
—
0
0
(40760888) Immunoglobulin light chains.free panel - Serum
0
10
0.00
0.21
0.0
1.8
—
—
—
0
0
(3006462) Nitrate [Presence] in Urine
0
10
0.00
0.21
0.0
2.1
—
—
—
0
0
(3032868) Hemoglobin electrophoresis panel in Blood
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
(3023659) Complement C1 esterase inhibitor.functional/Complement C1 esterase inhibitor.total in Serum or Plasma
0
12
0.00
0.21
0.0
1.3
—
99.5
—
0
12
(3003740) Influenza virus B Ag [Presence] in Specimen
10
80
1.26
0.20
1.0
1.1
—
—
—
0
0
(3002523) Influenza virus A Ag [Presence] in Specimen
10
80
1.26
0.20
1.0
1.1
—
—
—
0
0
(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture
18
208
0.86
0.20
1.6
1.6
—
—
—
0
0
(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay
19
218
0.86
0.20
1.7
2.0
—
—
—
0
0
(3012336) Haptoglobin [Mass/volume] in Serum or Plasma
6
49
1.23
0.20
4.7
2.7
g/l
1.0
1.0
—
6
44
(4198724)
6
50
1.20
0.20
3.2
2.3
—
—
—
0
0
(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum
16
137
1.18
0.19
1.3
1.2
—
61.1
—
0
6
(3043849) Epstein Barr virus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection
6
53
1.13
0.19
7.5
8.2
—
4633.4
—
0
5
(40760892) CBC W Ordered Manual Differential panel - Blood
63
592
1.08
0.18
6.4
4.4
—
—
—
0
0
(1001926) Buprenorphine [Presence] in Urine by Screen method
32
349
0.91
0.16
1.6
2.3
—
—
—
0
0
(1002224) Polysomnography panel
11
92
1.20
0.16
1.1
1.1
—
—
—
0
0
(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood
8
73
1.10
0.16
26.6
13.1
%
1.1
1.5
—
8
73
(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay
6
79
0.75
0.15
1.0
1.1
—
—
—
0
0
(3014148) Varicella zoster virus Ab [Titer] in Serum
6
80
0.75
0.15
1.2
1.1
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
81
774
1.06
0.15
3.8
2.8
—
—
—
0
0
(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma
15
171
0.87
0.15
1.5
1.5
—
—
—
0
0
(3018171) Choriogonadotropin [Units/volume] in Serum or Plasma
26
283
0.91
0.13
2.3
2.5
u/l
9543.7
4991.7
—
9
129
(3028707) Methadone [Presence] in Urine by Screen method
17
188
0.90
0.11
2.0
3.1
—
—
—
0
0
(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma
17
188
0.90
0.11
1.5
1.7
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
62
646
0.95
0.10
1.6
1.7
—
—
—
0
0
(3019225) pH of Specimen
13
115
1.14
0.10
1.8
4.4
—
—
—
0
0
(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method
5
47
1.06
0.09
1.4
1.1
—
—
—
0
0
(3001019) Free T4 and TSH panel - Serum or Plasma
11
124
0.88
0.09
1.9
1.5
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
113
1104
1.04
0.09
2.1
1.8
—
—
—
0
0
(3035350) Ketones [Presence] in Urine by Test strip
105
1025
1.04
0.08
3.7
2.9
estimate
0.0
0.0
0.00
26
208
(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay
10
113
0.88
0.08
1.4
1.2
—
—
—
0
0
(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum
16
146
1.10
0.08
2.5
2.2
—
24.1
—
0
15
(3000330) Specific gravity of Urine by Test strip
5
62
0.80
0.08
2.2
2.2
—
—
—
0
0
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
194
1915
1.03
0.08
3.2
2.6
mmol/l
2.7
2.8
1.33
185
1795
(3045414) Leukocytes [Presence] in Urine
6
74
0.81
0.07
2.0
1.6
—
—
—
0
0
(3009261) Glucose [Presence] in Urine by Test strip
106
1038
1.03
0.07
3.7
2.9
estimate
0.0
0.0
0.00
25
213
(3007566) Smooth muscle Ab [Titer] in Serum
9
85
1.06
0.07
1.7
1.5
—
57.3
—
0
11
(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay
10
111
0.90
0.06
1.6
1.4
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
45
465
0.96
0.05
2.2
2.4
—
—
—
0
0
(3007080) Epstein Barr virus nuclear IgG Ab [Units/volume] in Serum
15
139
1.08
0.05
2.2
1.5
u/ml
167.4
185.2
—
9
76
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
182
1802
1.02
0.05
2.9
2.4
mmol/l
1.1
1.2
0.11
176
1711
(3037467) Urinalysis macro (dipstick) panel - Urine
147
1453
1.02
0.04
4.6
3.5
—
—
—
0
0
(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma
162
1635
0.98
0.04
3.6
2.8
u/l
38.2
30.3
0.81
157
1574
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
264
2652
0.97
0.03
4.1
3.8
—
—
—
0
0
(3015736) pH of Urine
85
837
1.02
0.03
3.5
2.8
—
—
—
0
0
(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection
51
499
1.03
0.03
2.4
2.0
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
79
800
0.98
0.02
1.9
1.8
—
—
—
0
0
(3021601) Nitrite [Presence] in Urine by Test strip
104
1030
1.01
0.02
5.1
4.0
estimate
0.0
0.0
0.00
25
223
(3017895) Helicobacter pylori Ab [Units/volume] in Serum
10
93
1.08
0.02
1.5
1.7
—
—
—
0
0
(3011288) Drugs identified in Urine by Screen method
29
298
0.97
0.02
2.1
3.0
—
—
—
0
0
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
14
133
1.06
0.01
4.3
4.0
—
—
—
0
0
(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay
15
143
1.05
0.01
2.1
1.5
—
—
—
0
0
(3023421) Hepatitis B virus surface Ab [Units/volume] in Serum
19
183
1.04
0.01
1.2
1.4
miu/ml
346.8
291.3
—
8
95
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
193
1922
1.01
0.01
3.2
2.6
mmol/l
4.4
4.5
0.51
186
1818
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
191
1902
1.01
0.01
3.1
2.5
mmol/l
1.5
1.4
2.43
184
1798
(3029937) Albumin [Presence] in Urine by Test strip
55
543
1.02
0.01
4.4
3.1
estimate
0.0
0.0
0.50
25
215
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
64
633
1.01
0.01
1.6
1.5
—
—
—
0
0
(3048929) Epstein Barr virus Ab [Presence] in Serum
29
288
1.01
0.00
1.8
1.4
—
—
—
0
0
(3002256) Pathology report gross observation
18
183
0.98
0.00
1.2
1.2
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
75
753
0.99
0.00
2.0
1.8
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
94
944
0.99
0.00
3.6
4.2
—
—
—
0
0
(3006441) Cardiolipin IgM Ab [Presence] in Serum by Immunoassay
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3043410) Blood group antigens tested for on Red Blood Cells
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(42870298) TPMT gene c.238G>C+460G>A+719A>G [Identifier] in Blood or Tissue by Molecular genetics method Narrative
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(42869547) Procollagen type III.N-terminal propeptide [Mass/volume] in Serum
0
7
0.00
0.00
0.0
1.0
—
9.1
—
0
7
(3042517) Benzodiazepines panel - Urine
0
8
0.00
0.00
0.0
3.4
—
—
—
0
0
(40758292) HTLV I+II Ab panel - Serum
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3041365) Herpes simplex virus IgG Ab [Units/volume] in Serum by Immunoassay
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood
5
58
0.86
0.00
11.8
4.9
%
49.8
52.4
—
5
58
(3044927) Protein electrophoresis panel - Urine
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3036535) Thyroglobulin [Mass/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
10.6
—
—
—
0
0
(3034891) Synovial lining cells/100 cells in Synovial fluid
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3013784) Calcium.ionized [Moles/volume] in Serum or Plasma by Ion-selective membrane electrode (ISE)
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
(37021073) Hepatitis C virus genotype in Serum or Plasma by Sequencing
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3044212) Herpes simplex virus 1+2 IgM Ab [Presence] in Cerebral spinal fluid
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3011436) Histone Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3022689) Creatine [Moles/volume] in Urine
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3009871) Measles virus Ab [Titer] in Serum
0
7
0.00
0.00
0.0
2.3
—
—
—
0
0
(3010156) C reactive protein [Mass/volume] in Serum or Plasma by High sensitivity method
12
120
1.00
0.00
1.3
1.7
mg/l
4.7
2.8
—
6
68
(3012984) Norclozapine [Mass/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
14.0
—
—
—
0
0
(3002619) Bacteria identified in Specimen by Culture
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3022058) Hepatitis B virus DNA [Presence] in Serum or Plasma by NAA with probe detection
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3012320) Pathologist interpretation of Cerebral spinal fluid tests
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(40761539) Cells [Type] in Urine sediment by Light microscopy
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3017509) Phencyclidine [Presence] in Urine
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3014300) Beta 2 glycoprotein 1 IgM Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count
0
7
0.00
0.00
0.0
10.4
—
—
—
0
0
(3033888) Pepsinogen I [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.0
—
75.1
—
0
5
(4133840)
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(40765096) Chromosome analysis panel by Banding
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3001964) Herpes simplex virus Ag [Presence] in Specimen
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
(3037677) Mycoplasma pneumoniae IgM Ab [Titer] in Cerebral spinal fluid
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(42868647) JC virus Ab [Presence] in Serum or Plasma by Immunoassay
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3010015) Selenium [Moles/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
3.3
—
1.2
—
0
7
(3004446) Plasmodium sp identified in Blood by Light microscopy
0
8
0.00
0.00
0.0
3.1
—
—
—
0
0
(43055222) Platelet function.collagen + Adenosine diphosphate induced and EPINEPHrine induced panel - Blood
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(40760847) Basement membrane Ab [Titer] in Serum by Immunofluorescence
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3031072) Herpes simplex virus 1 IgG Ab [Presence] in Cerebral spinal fluid
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3038864) risperiDONE [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.2
—
21.9
—
0
5
(40760435) Tropomyosin IgE Ab [Units/volume] in Serum
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3041082) Glomerular basement membrane Ab [Titer] in Serum by Immunofluorescence
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(40771527) Human papilloma virus E6+E7 mRNA [Presence] in Cervix by NAA with probe detection
0
7
0.00
0.00
0.0
2.1
—
—
—
0
0
(3034770) Mitochondria Ab [Titer] in Serum
8
87
0.92
0.00
1.6
1.5
—
—
—
0
0
(42868421) Varicella zoster virus IgM Ab [Presence] in Cerebral spinal fluid by Immunoassay
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
(3010254) Herpes simplex virus identified in Specimen by Organism specific culture
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(40761849) Varicella zoster virus IgG Ab [Units/volume] in Cerebral spinal fluid by Immunoassay
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
(4035726)
9
91
0.99
0.00
1.7
1.7
—
—
—
0
0
(3017704) Immunofixation for Urine
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
88
880
1.00
0.00
1.8
1.7
—
—
—
0
0
(3007463) Buprenorphine [Presence] in Urine
0
8
0.00
0.00
0.0
4.9
—
—
—
0
0
(3022192) Triglyceride [Mass/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
2.3
—
—
—
0
0
(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3002823) Mycoplasma pneumoniae IgG Ab [Units/volume] in Cerebral spinal fluid
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
2.0
—
12.0
—
0
5

Mortality – FinRegistry

↥

Association

Association between endpoint E4_DELPUB and mortality.

Females

No data

Males

Parameter HR [95% CI] p-value
E4_DELPUB 1.963 [1.44, 2.68] < 0.001
Birth year 0.985 [0.98, 1.0] 0.003

During the follow-up period (1.1.1998 — 31.12.2019), 74 out of 5417 males with E4_DELPUB died.

Mortality risk

Mortality risk for people of age

years, who have E4_DELPUB.

N-year risk Females Males
1 No data 0.338%
5 No data 2.166%
10 No data 5.179%
15 No data 10.013%
20 No data 16.731%

Relationships between endpoints

↥

Index endpoint: E4_DELPUB – Delayed puberty

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data