This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Cystic fibrosis with pulmonary manifestations
E4_CYSFIBRO_PUL
obsolete_cystic fibrosis: ['A congenital metabolic disorder affecting the exocrine glands, inherited as an autosomal trait. The secretions of exocrine glands are abnormal, resulting in excessively viscid mucus production which causes obstruction of passageways (including pancreatic and bile ducts, intestines, and bronchi). The sweat sodium and chloride content are increased. Symptoms usually appear in childhood and include meconium ileus, poor growth despite good appetite, malabsorption and foul bulky stools, chronic bronchitis with cough, recurrent pneumonia, bronchiectasis, emphysema, clubbing of the fingers, and salt depletion in hot weather. -- 2003', 'A congenital metabolic disorder affecting the exocrine glands, inherited as an autosomal trait. The secretions of exocrine glands are abnormal, resulting in excessively viscid mucus production which causes obstruction of passageways (including pancreatic and bile ducts, intestines, and bronchi). The sweat sodium and chloride content are increased. Symptoms usually appear in childhood and include meconium ileus, poor growth despite good appetite, malabsorption and foul bulky stools, chronic bronchitis with cough, recurrent pneumonia, bronchiectasis, emphysema, clubbing of the fingers, and salt depletion in hot weather.']
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
47 |
4. Check minimum number of eventsNone |
47 |
5. Include endpointsNone |
47 |
6. Filter based on genotype QC (FinnGen only) |
47 |
Control definitions (FinnGen only)
- Control exclude
- E4_METABOLIA
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- E84
- Name in latin
- Fibrosis cystica cum manifestationibus pulmonalibus
Similar endpoints
↥List of similar endpoints to
Cystic fibrosis with pulmonary manifestations
based on the number of shared cases.
Similar with more cases:
- Cystic fibrosis
- Metabolic disorders
- Endocrine, nutritional and metabolic diseases
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 234 | 117 | 115 |
| Only index persons | 195 | 103 | 92 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.00 | 0.00 | 0.00 |
| Only index persons | 0.00 | 0.00 | 0.00 |
| Median age at first event (years) | |||
| Whole population | 26.39 | 33.91 | 18.12 |
| Only index persons | 27.69 | 33.91 | 20.71 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 47 | 24 | 23 |
| Unadjusted period prevalence (%) | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | 14.05 | 12.63 | 15.52 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
No data
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
No data available
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3020779) Urea [Moles/volume] in Serum or Plasma
35
20
65.63
47.79
20.6
6.5
mmol/l
7.3
5.3
1.20
35
20
(3000494) Fungus identified in Specimen by Culture
37
31
52.40
42.13
14.3
1.3
—
—
—
0
0
(3023419) Bacteria identified in Sputum by Culture
31
0
+∞
37.63
23.2
0.0
—
—
—
0
0
(3005322) IgE [Units/volume] in Serum or Plasma
31
26
33.09
34.40
3.7
1.2
u/ml
113.7
1010.4
0.55
31
26
(4010399)
27
20
30.38
31.56
3.8
1.1
—
—
—
0
0
(3005719) IgG [Mass/volume] in Serum or Plasma
27
22
27.49
29.95
5.5
4.1
g/l
10.1
10.2
0.07
27
22
(43055120) Cytomegalovirus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection
21
10
37.15
29.35
26.0
2.9
iu/ml
107.4
—
—
5
0
(3016407) Fibrinogen [Mass/volume] in Platelet poor plasma by Coagulation assay
30
7
112.39
29.26
5.5
1.6
g/l
3.6
3.0
—
30
7
(3042936) Bacteria identified in Isolate by Culture
32
37
24.97
29.12
5.2
2.1
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
29
29
24.50
28.68
4.9
1.5
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
29
30
23.63
28.06
5.3
1.5
—
—
—
0
0
(3019250) Coagulation factor VIII activity actual/normal in Platelet poor plasma by Coagulation assay
28
5
132.16
28.03
5.9
3.8
%
168.1
141.6
—
28
5
(3020717) Zinc [Moles/volume] in Serum or Plasma
24
0
+∞
27.89
3.5
0.0
umol/l
13.1
—
—
24
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
33
44
22.82
27.21
6.4
1.9
—
—
—
0
0
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
27
5
121.27
26.72
6.4
1.0
—
—
—
0
0
(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method
29
9
79.95
26.67
5.9
1.7
%
92.9
93.1
—
29
9
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
25
5
102.39
24.16
4.9
1.6
—
—
—
0
0
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
25
5
102.39
24.16
5.6
1.6
—
—
—
0
0
(3028026) IgM [Mass/volume] in Serum or Plasma
22
18
22.10
23.83
3.5
2.6
g/l
1.2
1.4
0.15
22
18
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
24
5
94.15
22.91
4.9
1.2
—
—
—
0
0
(3018418) pH of Serum or Plasma
36
69
19.02
22.25
12.4
2.9
ph
7.4
7.4
0.73
14
12
(3000492) Spirometry study
28
38
16.75
22.19
3.9
1.4
—
—
—
0
0
(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
22
5
79.59
20.48
4.9
1.6
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
23
27
15.72
19.83
4.5
1.4
—
—
—
0
0
(3015377) Calcium [Moles/volume] in Serum or Plasma
40
88
24.59
19.36
9.9
2.4
mmol/l
2.3
2.4
1.72
40
81
(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection
21
5
73.13
19.29
5.4
1.0
—
—
—
0
0
(3033658) Prothrombin time (PT) actual/Normal
34
74
14.00
18.30
15.7
2.7
%
97.4
95.7
0.17
34
74
(42870588) Differential panel, method unspecified - Blood
41
109
22.46
17.58
31.9
5.5
—
—
—
0
0
(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma
42
122
23.81
17.15
10.6
2.3
nmol/l
74.0
72.1
0.20
42
110
(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma
41
115
20.94
16.81
19.4
4.3
mmol/l
1.2
1.2
0.09
41
102
(3035509) Tobramycin [Mass/volume] in Serum or Plasma
15
0
+∞
16.62
6.3
0.0
mg/l
0.7
—
—
10
0
(3049714) Procollagen type I.N-terminal propeptide [Mass/volume] in Serum
15
0
+∞
16.62
3.7
0.0
ug/l
54.2
—
—
15
0
(3032080) INR in Blood by Coagulation assay
35
89
12.49
16.06
7.3
3.3
inr
1.1
1.0
0.38
17
27
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
33
79
11.67
15.94
5.5
1.3
mg/l
0.7
0.7
0.06
22
47
(3020630) Protein [Mass/volume] in Serum or Plasma
15
12
17.89
15.92
2.0
4.1
g/l
69.1
66.2
0.65
15
12
(3002179) Metamyelocytes/100 leukocytes in Blood
19
24
12.61
15.20
10.4
4.5
%
0.9
0.3
—
7
7
(3017181) Myelocytes/100 leukocytes in Blood
19
26
11.59
14.28
11.1
4.3
%
0.8
0.5
—
9
11
(3008536) Aspergillus sp Ab [Presence] in Serum
13
0
+∞
14.27
1.3
0.0
—
—
—
0
0
(3006695) Toxoplasma gondii DNA [Presence] in Specimen by NAA with probe detection
13
0
+∞
14.27
4.5
0.0
—
—
—
0
0
(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma
39
120
14.13
14.03
9.7
2.0
u/l
25.6
26.6
0.21
39
113
(3025159) Blasts/100 leukocytes in Blood
18
24
11.53
13.74
11.2
4.5
%
0.0
0.0
—
7
8
(3021440) Promyelocytes/100 leukocytes in Blood
18
26
10.60
12.87
11.7
4.3
%
0.0
0.2
—
8
10
(3023368) Bacteria identified in Blood by Culture
27
64
8.56
12.61
12.9
4.0
—
—
—
0
0
(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma
30
80
8.60
12.51
4.0
1.8
mg/l
3.0
2.7
0.41
30
65
(3012516) Albumin [Mass/volume] in Urine
26
60
8.46
12.43
4.0
2.9
mg/l
162.8
157.3
0.02
21
37
(3019069) Monocytes/100 leukocytes in Blood
41
165
12.58
11.58
39.5
5.4
%
8.4
8.4
0.02
41
158
(3006504) Eosinophils/100 leukocytes in Blood
41
166
12.46
11.50
39.3
5.3
%
2.9
2.6
0.33
41
155
(3001604) Monocytes [#/volume] in Blood
42
176
13.97
11.45
38.2
5.7
e9/l
0.6
0.6
1.09
42
161
(3006315) Basophils [#/volume] in Blood
42
177
13.84
11.41
38.2
5.7
e9/l
0.0
0.0
0.61
42
162
(3013115) Eosinophils [#/volume] in Blood
42
183
13.12
11.03
40.3
5.9
e9/l
0.2
0.2
0.83
42
168
(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection
14
6
32.22
11.01
2.7
1.5
—
—
—
0
0
(3022096) Basophils/100 leukocytes in Blood
40
161
10.92
10.97
40.0
5.4
%
0.6
0.6
0.03
40
154
(3036432) Mycobacterium tuberculosis genotype [Identifier] in Isolate
10
0
+∞
10.82
21.6
0.0
—
—
—
0
0
(40758558) Short blood count panel - Blood
30
90
7.45
10.79
21.3
6.0
—
—
—
0
0
(3018010) Neutrophils/100 leukocytes in Blood
41
174
11.58
10.76
36.3
4.9
%
58.2
55.9
0.86
41
167
(3002030) Lymphocytes/100 leukocytes in Blood
41
177
11.27
10.55
39.4
5.2
%
27.7
30.2
0.93
41
171
(3019060) Gas panel - Arterial blood
12
13
12.05
10.33
1.7
2.0
—
—
—
0
0
(40757373) Influenza virus identified in Isolate
9
0
+∞
9.70
3.9
0.0
—
—
—
0
0
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
12
15
10.40
9.30
2.3
1.9
—
—
—
0
0
(3032035) Polymorphonuclear cells/100 leukocytes in Blood
10
10
12.43
8.96
10.5
4.6
%
62.9
51.1
—
10
10
(3030905) Polymorphonuclear cells [#/volume] in Blood
10
10
12.43
8.96
10.3
4.5
e9/l
6.1
2.8
—
10
10
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
13
22
7.79
7.86
4.2
1.5
—
—
—
0
0
(3042733) HLA Ab [Presence] in Serum
7
0
+∞
7.48
2.4
0.0
—
—
—
0
0
(3012544) pH of Venous blood
13
25
6.81
6.94
10.3
4.6
—
—
—
0
0
(3027653) Mycophenolate [Mass/volume] in Serum or Plasma
6
0
+∞
6.38
4.8
0.0
mg/l
2.0
—
—
6
0
(36659890) Mycobacterial identification panel - Specimen by Molecular genetics method
6
0
+∞
6.38
6.0
0.0
—
—
—
0
0
(3001122) Ferritin [Mass/volume] in Serum or Plasma
34
161
5.02
6.19
6.0
2.4
ug/l
92.1
71.8
0.44
34
146
(36304419) Bacteria [Presence] in Urine
25
96
4.43
5.97
8.7
2.7
—
—
—
0
0
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
23
83
4.47
5.96
4.6
2.4
ng/l
50.4
30.9
0.25
16
42
(3044889) 12 lead EKG panel
37
191
5.40
5.93
11.7
3.0
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
28
121
4.25
5.61
10.9
3.1
—
—
—
0
0
(4035726)
10
19
6.42
5.30
1.9
1.6
—
—
—
0
0
(3024932) HLA-DR beta [Type]
5
0
+∞
5.29
1.0
0.0
—
—
—
0
0
(3020229) Cytomegalovirus DNA [Presence] in Specimen by NAA with probe detection
5
0
+∞
5.29
1.2
0.0
—
—
—
0
0
(3013803) Aspergillus fumigatus IgG Ab [Mass/volume] in Serum
5
0
+∞
5.29
1.2
0.0
—
—
—
0
0
(3035400) Alkaline phosphatase.liver [Enzymatic activity/volume] in Serum or Plasma
5
0
+∞
5.29
2.6
0.0
u/l
177.2
—
—
5
0
(3016273) Islet cell 512 Ab [Units/volume] in Serum
5
0
+∞
5.29
1.0
0.0
—
—
—
0
0
(3024471) HLA-A [Type]
5
0
+∞
5.29
1.0
0.0
—
—
—
0
0
(3045684) Alkaline phosphatase.other fractions [Enzymatic activity/volume] in Serum or Plasma
5
0
+∞
5.29
2.6
0.0
u/l
40.4
—
—
5
0
(40760892) CBC W Ordered Manual Differential panel - Blood
22
84
4.04
5.16
24.3
5.2
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
26
113
3.91
5.04
3.8
1.8
—
—
—
0
0
(3000850) Epithelial cells [#/volume] in Urine
20
74
3.96
4.86
6.8
2.0
e6/l
3.5
5.7
0.88
20
66
(3000991) Gas panel - Venous blood
11
26
5.22
4.64
19.5
5.7
—
—
—
0
0
(3026782) Osmolality of Urine
19
71
3.81
4.50
7.5
2.2
mosm/kgh2o
484.5
567.9
1.01
19
60
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
10
23
5.25
4.32
5.6
2.7
—
—
—
0
0
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
13
38
4.35
4.26
1.8
2.0
—
—
—
0
0
(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay
9
14
7.65
4.21
1.2
1.1
—
—
—
0
0
(3030366) Cystatin C [Mass/volume] in Serum or Plasma
8
11
8.49
4.04
6.1
7.0
mg/l
1.7
1.2
—
8
11
(3011397) Hemoglobin [Presence] in Urine by Test strip
19
76
3.52
4.01
3.7
3.4
—
—
—
0
0
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
24
112
3.34
3.96
1.9
1.5
u/ml
0.5
1.5
—
5
16
(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay
7
8
10.01
3.91
1.1
1.3
—
—
—
0
0
(3014148) Varicella zoster virus Ab [Titer] in Serum
7
8
10.01
3.91
1.1
1.4
—
—
—
0
0
(4268621)
6
5
13.45
3.87
2.3
2.6
—
—
—
0
0
(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma
14
47
3.82
3.79
1.9
1.5
pmol/l
629.6
450.3
0.90
14
38
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
8
13
7.16
3.67
2.8
1.3
—
—
—
0
0
(3035350) Ketones [Presence] in Urine by Test strip
30
166
3.23
3.64
5.7
3.1
estimate
0.0
0.0
—
10
35
(3004588) Protein electrophoresis panel - Serum or Plasma
6
6
11.20
3.60
1.3
6.8
—
—
—
0
0
(3021601) Nitrite [Presence] in Urine by Test strip
30
167
3.20
3.58
8.2
4.2
estimate
0.0
0.0
0.00
12
34
(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma
39
262
3.86
3.56
11.3
2.4
u/l
38.4
32.3
0.35
39
251
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
8
14
6.64
3.51
18.8
4.9
mmol/l
24.5
25.5
—
8
14
(3009261) Glucose [Presence] in Urine by Test strip
30
171
3.09
3.37
5.6
3.2
estimate
0.0
0.0
0.00
12
33
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
39
269
3.63
3.30
6.2
3.2
pmol/l
14.1
14.4
0.30
39
249
(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma
7
12
6.63
3.14
1.6
1.0
—
—
—
0
0
(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma
7
12
6.63
3.14
1.6
1.0
—
—
—
0
0
(3022313) Gas panel - Capillary blood
7
12
6.63
3.14
12.3
3.3
—
—
—
0
0
(3022145) Colonoscopy Study observation
10
30
3.96
3.10
1.0
1.5
—
—
—
0
0
(1616796) Gas panel - Central venous blood
5
5
10.96
3.05
9.0
1.4
—
—
—
0
0
(3025941) Bacteria identified in Stool by Culture
7
13
6.11
2.99
1.4
1.3
—
—
—
0
0
(3048929) Epstein Barr virus Ab [Presence] in Serum
10
31
3.83
2.97
1.3
1.3
—
—
—
0
0
(3015736) pH of Urine
24
128
2.79
2.94
4.5
3.1
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
19
90
2.87
2.90
5.0
2.4
—
—
—
0
0
(3021960) Folate [Moles/volume] in Serum or Plasma
14
58
3.01
2.67
2.6
1.3
nmol/l
24.3
20.5
0.48
14
51
(3004490) Bicarbonate [Moles/volume] standard in Capillary blood
6
11
6.07
2.63
10.2
3.6
mmol/l
24.7
24.0
—
6
11
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
19
95
2.68
2.57
2.5
1.6
pmol/l
85.8
101.1
0.89
14
53
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
6
12
5.55
2.48
16.3
3.0
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
34
230
2.73
2.44
11.4
3.9
—
—
—
0
0
(3052851) Hemolysis interference index of Serum or Plasma
5
8
6.83
2.43
1.6
3.3
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
19
99
2.54
2.34
4.9
2.4
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
23
132
2.45
2.30
5.1
2.9
—
—
—
0
0
(3017766) Complement C4 [Mass/volume] in Serum or Plasma
6
14
4.74
2.22
2.3
1.3
g/l
0.2
0.2
—
6
14
(3000620) Complement C3 [Mass/volume] in Serum or Plasma
6
14
4.74
2.22
2.3
1.3
g/l
1.0
1.2
—
6
14
(40768797) Stomach Pathology biopsy report
9
34
3.03
1.99
1.2
1.1
—
—
—
0
0
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
5
11
4.94
1.99
2.4
1.1
—
—
—
0
0
(3020891) Body temperature
5
11
4.94
1.99
1.2
4.9
—
—
—
0
0
(3029937) Albumin [Presence] in Urine by Test strip
17
93
2.30
1.82
5.3
3.4
estimate
0.0
0.0
—
9
31
(3024891) Influenza virus A+B Ag [Presence] in Specimen
5
13
4.17
1.76
1.0
1.0
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
13
64
2.43
1.74
5.4
2.4
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
6
132
0.38
1.62
1.7
1.8
—
—
—
0
0
(3014007) Fractional oxyhemoglobin in Arterial blood
5
15
3.60
1.56
23.0
4.8
%
95.8
91.2
—
5
15
(3006217) Methemoglobin/Hemoglobin.total in Arterial blood
5
15
3.60
1.56
23.0
4.7
%
0.9
0.8
—
5
15
(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood
5
16
3.37
1.47
23.0
4.6
%
1.1
2.0
—
5
16
(40761536) Microorganisms panel - Urine sediment
8
34
2.62
1.37
5.5
2.6
—
—
—
0
0
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
39
320
2.28
1.35
6.7
3.0
mmol/l
6.2
5.6
1.41
39
295
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
22
152
1.84
1.18
7.2
3.6
—
—
—
0
0
(3013512) EKG study
13
75
2.01
1.17
6.1
2.8
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
9
48
2.08
1.08
1.7
1.1
—
—
—
0
0
(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma
0
29
0.00
1.02
0.0
1.6
—
—
—
0
0
(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma
0
31
0.00
1.00
0.0
1.7
—
—
—
0
0
(3021879) Hepatitis B virus core Ab [Presence] in Serum
8
47
1.84
0.86
2.5
1.7
—
—
—
0
0
(3047352) Trisomy 18 risk [Likelihood] in Fetus
0
24
0.00
0.82
0.0
1.5
—
—
—
0
0
(3005033) Fetal Nuchal fold Thickness US
0
24
0.00
0.82
0.0
1.5
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
40
354
1.87
0.82
4.7
3.6
—
—
—
0
0
(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma
0
25
0.00
0.82
0.0
1.7
—
—
—
0
0
(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age
0
26
0.00
0.81
0.0
1.5
—
—
—
0
0
(3043238) Trisomy 21 risk [Likelihood] in Fetus
0
26
0.00
0.81
0.0
1.5
—
—
—
0
0
(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma
0
26
0.00
0.81
0.0
1.5
—
—
—
0
0
(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma
0
26
0.00
0.81
0.0
1.5
—
—
—
0
0
(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight
0
26
0.00
0.81
0.0
1.5
—
—
—
0
0
(3002256) Pathology report gross observation
5
28
1.88
0.68
1.0
1.3
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
16
116
1.58
0.66
2.9
2.0
—
—
—
0
0
(3001019) Free T4 and TSH panel - Serum or Plasma
0
19
0.00
0.62
0.0
1.5
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
19
146
1.51
0.60
2.3
2.4
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
13
93
1.55
0.56
3.2
2.5
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
15
118
1.40
0.40
2.3
1.8
—
—
—
0
0
(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma
5
36
1.43
0.39
5.0
3.6
%
32.6
30.7
—
5
26
(3027944) Amphetamines [Presence] in Urine
6
43
1.45
0.37
1.0
2.3
—
—
—
0
0
(3027008) Opiates [Presence] in Urine
6
44
1.42
0.36
1.0
2.3
—
—
—
0
0
(3028300) Cannabinoids [Presence] in Urine
6
44
1.42
0.36
1.0
2.3
—
—
—
0
0
(3000764) Benzodiazepines [Presence] in Urine
6
44
1.42
0.36
1.0
2.3
—
—
—
0
0
(3004716) Salmonella sp identified in Stool by Organism specific culture
5
38
1.35
0.24
1.2
1.3
—
—
—
0
0
(3016879) Cocaine [Presence] in Urine
5
40
1.28
0.23
1.0
2.4
—
—
—
0
0
(44816844) Macroprolactin [Units/volume] in Serum or Plasma
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
(3017143) Hepatitis C virus Ab [Presence] in Serum
10
81
1.30
0.21
2.8
1.6
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
12
100
1.27
0.20
1.2
1.9
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
14
120
1.24
0.19
1.4
1.7
—
—
—
0
0
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
10
118
0.81
0.16
1.6
2.8
—
—
—
0
0
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
11
106
1.05
0.00
1.5
2.6
—
—
—
0
0
(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
8
78
1.03
0.00
1.6
1.3
—
—
—
0
0
(3000081) cloZAPine [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
17.6
—
1328.8
—
0
5
(3019897) Erythrocyte distribution width [Ratio] by Automated count
0
6
0.00
0.00
0.0
1.0
—
13.8
—
0
6
(3042975) Streptococcus sp identified in Isolate by Organism specific culture
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3045142) Bone marrow Pathology biopsy report
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3050238) Crystals [Presence] in Synovial fluid by Light microscopy
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3019497) Choriogonadotropin.beta subunit free [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3035947) Staphylolysin Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(36032269) Testosterone Free [Moles/volume] in Serum or Plasma by calculation
0
6
0.00
0.00
0.0
1.0
—
326.5
—
0
6
(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3013201) Beta-2-Microglobulin [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.0
—
5.1
—
0
5
(3043109) Cytology report of Tissue fine needle aspirate Cyto stain
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(3023420) DNA double strand Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3049717) Cytology report of Urine Cyto stain
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3042111) Morphology [Interpretation] in Bone marrow Narrative
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3025018) Bordetella pertussis Ab [Titer] in Serum
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
(3041806) Other cells [#/volume] in Blood by Manual count
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.5
—
94.7
—
0
6
(3024666) Lithium, Blood [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
12.6
—
0.6
—
0
5
(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3008832) Norclozapine [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
17.6
—
792.2
—
0
5
(3047007) Chlamydophila sp Ab [Presence] in Serum
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint E4_CYSFIBRO_PUL and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have E4_CYSFIBRO_PUL.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: E4_CYSFIBRO_PUL – Cystic fibrosis with pulmonary manifestations
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data