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This is a non-core endpoint: only basic statistics are computed.

Duodenal ulcer - Acute with perforation, drug-induced

DUODENAL_ULCER_ACUTE_W_PERFORATION

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ATC codes for adverse effects of Drugs ANY
  • Hospital discharge: ICD-10 K26.1#

1 out of 7 registries used, show all original rules.

8

4. Check minimum number of events

None

8

5. Include endpoints

None

8

6. Filter based on genotype QC (FinnGen only)

8

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF5

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (not available in FinRegistry).

-FinnGen-

Key figures

All Female Male
Number of individuals 8 - 5
Unadjusted period prevalence (%) 0.00 - 0.00
Median age at first event (years) 50.80 - 50.92

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3031040) Bacteria [#/volume] in Urine by Automated count
8
45
+∞
1.71
6.0
4.7
—
—
—
0
0
(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma
0
30
0.00
1.33
0.0
2.0
—
74.7
—
0
23
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
0
15
0.00
0.47
0.0
1.8
—
0.2
—
0
9
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
8
70
+∞
0.23
26.1
17.6
mg/l
26.5
28.3
—
8
55
(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma
0
12
0.00
0.23
0.0
5.8
—
31.8
—
0
6
(3003694) ABO and Rh group [Type] in Blood
0
13
0.00
0.22
0.0
1.3
—
—
—
0
0
(3020564) Creatinine [Moles/volume] in Serum or Plasma
8
74
+∞
0.00
30.1
23.4
umol/l
69.6
89.7
—
8
74
(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum
0
8
0.00
0.00
0.0
2.3
—
—
—
0
0
(3020779) Urea [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
13.3
—
12.2
—
0
6
(3002256) Pathology report gross observation
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(40761511) CBC panel - Blood by Automated count
8
72
+∞
0.00
26.1
17.6
—
—
—
0
0
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
(3049717) Cytology report of Urine Cyto stain
0
6
0.00
0.00
0.0
4.5
—
—
—
0
0
(4010399)
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3000492) Spirometry study
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (not available in FinRegistry).

Relationships between endpoints

Index endpoint: DUODENAL_ULCER_ACUTE_W_PERFORATION – Duodenal ulcer - Acute with perforation, drug-induced

GWS hits: -

This endpoint is excluded (not available in FinRegistry).