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This is a non-core endpoint: only basic statistics are computed.

Pseudomembranous colitis, drug-induced

COLITENTER_ADVERSE

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ATC codes for adverse effects of Drugs ANY
  • Hospital discharge: ICD-10 K52.80#

1 out of 7 registries used, show all original rules.

14

4. Check minimum number of events

None

14

5. Include endpoints

None

14

6. Filter based on genotype QC (FinnGen only)

14

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF5
Parent code in ICD-10
K52
Name in latin
Colitis [haemorrhagica] ex usu antibioticorum

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 14 9 5
Unadjusted period prevalence (%) 0.00 0.00 0.00
Median age at first event (years) 44.95 43.85 46.91

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3044640) Blood type and Crossmatch panel - Blood
0
36
0.00
1.39
0.0
2.5
—
—
—
0
0
(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma
7
32
3.34
1.33
2.4
3.0
u/l
49.6
60.5
—
7
27
(3013512) EKG study
0
30
0.00
1.14
0.0
3.2
—
—
—
0
0
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
7
100
0.40
0.89
2.4
3.8
mmol/l
1.5
1.2
—
7
89
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
0
25
0.00
0.89
0.0
2.6
—
—
—
0
0
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
0
24
0.00
0.89
0.0
4.9
—
18.6
—
0
11
(40760892) CBC W Ordered Manual Differential panel - Blood
5
28
2.21
0.74
11.6
3.9
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
0
22
0.00
0.65
0.0
1.3
—
—
—
0
0
(3006315) Basophils [#/volume] in Blood
7
46
2.03
0.62
9.9
5.6
e9/l
0.0
0.0
—
7
38
(3001604) Monocytes [#/volume] in Blood
7
46
2.03
0.62
9.9
5.6
e9/l
0.5
0.6
—
7
38
(3019198) Lymphocytes [#/volume] in Blood
7
47
1.97
0.61
9.7
5.7
e9/l
1.9
1.7
—
7
41
(3003338) MCHC [Mass/volume]
6
84
0.50
0.58
17.0
20.0
g/l
335.3
331.5
—
6
84
(3041096) Erythrocytes [Presence] in Urine by Automated
5
31
1.94
0.50
2.2
3.3
—
—
—
0
0
(3026493) Urate [Moles/volume] in Serum or Plasma
5
34
1.73
0.46
1.0
2.4
umol/l
348.8
359.5
—
5
27
(42870588) Differential panel, method unspecified - Blood
5
35
1.66
0.45
9.2
4.9
—
—
—
0
0
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
8
99
0.55
0.44
3.6
4.8
mmol/l
5.4
5.8
—
8
94
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
0
15
0.00
0.44
0.0
2.1
—
—
—
0
0
(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma
0
14
0.00
0.44
0.0
1.1
—
1.3
—
0
7
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
0
14
0.00
0.44
0.0
2.5
—
2.3
—
0
6
(4010399)
0
14
0.00
0.44
0.0
1.3
—
—
—
0
0
(4035726)
0
14
0.00
0.44
0.0
1.1
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
0
14
0.00
0.44
0.0
1.6
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
0
14
0.00
0.44
0.0
1.6
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
6
44
1.63
0.42
2.7
4.3
—
—
—
0
0
(3013115) Eosinophils [#/volume] in Blood
7
50
1.79
0.41
9.9
5.3
e9/l
0.1
0.2
—
7
43
(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma
7
50
1.79
0.41
1.9
2.3
nmol/l
65.4
76.9
—
7
43
(3026008) Bacteria identified in Urine by Culture
5
37
1.54
0.28
3.2
2.6
—
—
—
0
0
(3013650) Neutrophils [#/volume] in Blood by Automated count
8
66
1.49
0.24
7.3
7.8
e9/l
2.9
4.5
—
8
55
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
8
68
1.41
0.23
3.0
4.0
—
—
—
0
0
(3014111) Lactate [Moles/volume] in Serum or Plasma
0
11
0.00
0.22
0.0
8.3
—
1.3
—
0
11
(3000991) Gas panel - Venous blood
0
11
0.00
0.22
0.0
8.5
—
—
—
0
0
(3023024) Carbon dioxide [Partial pressure] in Capillary blood
0
11
0.00
0.22
0.0
1.6
—
4.8
—
0
11
(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)
0
10
0.00
0.22
0.0
2.1
—
71.0
—
0
5
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
0
10
0.00
0.22
0.0
1.7
—
—
—
0
0
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
0
12
0.00
0.22
0.0
13.7
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
0
12
0.00
0.22
0.0
1.4
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
0
13
0.00
0.21
0.0
1.7
—
—
—
0
0
(3021589) Normoblasts [#/volume] in Blood
5
59
0.76
0.11
16.6
9.7
e9/l
0.0
0.0
—
5
51
(3013707) Erythrocyte sedimentation rate by Westergren method
9
82
1.27
0.11
7.0
4.3
mm/h
10.1
10.7
—
9
71
(3037467) Urinalysis macro (dipstick) panel - Urine
8
71
1.29
0.11
4.4
4.3
—
—
—
0
0
(3044889) 12 lead EKG panel
7
76
0.84
0.10
3.6
4.9
—
—
—
0
0
(3021447) Carbon dioxide [Partial pressure] in Venous blood
0
8
0.00
0.00
0.0
2.0
—
6.4
—
0
8
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
0
8
0.00
0.00
0.0
2.1
—
—
—
0
0
(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma
6
65
0.87
0.00
5.2
3.6
u/l
50.8
58.9
—
6
60
(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
2.9
—
9.2
—
0
9
(3020891) Body temperature
0
9
0.00
0.00
0.0
3.4
—
—
—
0
0
(3005322) IgE [Units/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
1.0
—
68.8
—
0
8
(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
(3024354) Oxygen [Partial pressure] in Venous blood
0
8
0.00
0.00
0.0
2.0
—
3.0
—
0
8
(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood
0
8
0.00
0.00
0.0
2.5
—
34.5
—
0
8
(3017446) Testosterone [Moles/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
2.4
—
10.0
—
0
8
(3043238) Trisomy 21 risk [Likelihood] in Fetus
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
0
7
0.00
0.00
0.0
1.7
—
2.2
—
0
7
(3022621) pH of Urine by Test strip
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3012544) pH of Venous blood
0
7
0.00
0.00
0.0
2.1
—
—
—
0
0
(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
0
6
0.00
0.00
0.0
2.3
—
—
—
0
0
(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3015235) Bicarbonate [Moles/volume] in Capillary blood
0
6
0.00
0.00
0.0
1.5
—
24.0
—
0
6
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3009214) Lutropin [Units/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.4
—
5.4
—
0
5
(3043109) Cytology report of Tissue fine needle aspirate Cyto stain
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3024889) Methemoglobin/Hemoglobin.total in Venous blood
0
6
0.00
0.00
0.0
1.8
—
1.1
—
0
6
(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma
0
6
0.00
0.00
0.0
5.3
—
36.2
—
0
6
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
0
5
0.00
0.00
0.0
3.4
—
—
—
0
0
(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method
0
5
0.00
0.00
0.0
2.4
—
83.6
—
0
5
(3005229) Alpha 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
0
5
0.00
0.00
0.0
3.4
—
7.5
—
0
5
(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3021387) Prolactin [Units/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.4
—
281.8
—
0
5
(3001019) Free T4 and TSH panel - Serum or Plasma
0
5
0.00
0.00
0.0
4.8
—
—
—
0
0
(3030981) Hyaline casts [#/volume] in Urine by Automated count
0
7
0.00
0.00
0.0
5.1
—
0.2
—
0
7
(40768793) Breast Pathology biopsy report
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3027273) Bicarbonate [Moles/volume] in Venous blood
0
7
0.00
0.00
0.0
2.1
—
24.1
—
0
7
(3006217) Methemoglobin/Hemoglobin.total in Arterial blood
0
5
0.00
0.00
0.0
17.4
—
0.8
—
0
5
(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood
0
5
0.00
0.00
0.0
17.4
—
1.1
—
0
5
(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3004119) Hemoglobin [Mass/volume] in Venous blood
0
7
0.00
0.00
0.0
2.1
—
137.4
—
0
7
(3022313) Gas panel - Capillary blood
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
5
46
1.13
0.00
1.2
2.7
—
—
—
0
0
(3047352) Trisomy 18 risk [Likelihood] in Fetus
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
(3029713) Protein.monoclonal band 1 [Mass/volume] in Serum or Plasma by Electrophoresis
0
5
0.00
0.00
0.0
3.4
—
1.3
—
0
5
(3005033) Fetal Nuchal fold Thickness US
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
5
52
0.94
0.00
4.2
4.1
—
—
—
0
0
(3028626) Oxygen [Partial pressure] in Capillary blood
0
7
0.00
0.00
0.0
1.3
—
8.0
—
0
7
(3019225) pH of Specimen
0
6
0.00
0.00
0.0
4.0
—
—
—
0
0
(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum
0
7
0.00
0.00
0.0
2.1
—
—
—
0
0
(3036489) Thrombin time
0
6
0.00
0.00
0.0
2.5
—
19.7
—
0
6
(3021901) Oxygen saturation in Capillary blood
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(4034850)
0
6
0.00
0.00
0.0
16.5
—
—
—
0
0
(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(1002224) Polysomnography panel
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3004248) Sex hormone binding globulin [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
2.2
—
34.4
—
0
5

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: COLITENTER_ADVERSE – Pseudomembranous colitis, drug-induced

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).